This page is updated frequently with new Noma-related patent applications.
| Distributed machine learning analytics framework for the analysis of streaming data sets from a computer environment|
Embodiments of the present innovation relate to a host device that includes a configured to receive a set of data elements from a computer infrastructure, the set of data elements relating to at least one attribute of at least one computer environment resource of the computer infrastructure. The controller is configured to assign each data element of the set of data elements to a data retention location based upon a time statistic identifier associated with each data element of the set of data elements and to compare a training data set and the data elements associated with a selected data retention location to detect a data anomaly associated with the set of data elements.
Sios Technology Corporation
| System and energy sample forecasting of hvac-r systems|
A technique for energy sample forecasting of heating, venting and air conditioning-refrigeration (hvac-r) systems is disclosed. In an example, a first expected energy sample of a hvac-r system at a first time period is forecasted by modelling actual energy samples of the hvac-r system at previous time periods using a statistically-based seasonal-autoregressive integrated moving average (sarima) model.
Tata Consultancy Services Limited
| Method for analyzing time series activity streams and devices thereof|
A method, non-transitory computer readable medium, and data manager computing device comprises retrieving a time series data of a monitored asset based on one or more tags in response to a request. Further, a heterogeneous data based on the one or more tags is retrieved.
| Apparatus and leveraging semi-supervised machine learning principals to perform root cause analysis and derivation for remediation of issues in a computer environment|
Embodiments of the innovation relate to a host device having a memory and a processor, the host device configured to determine an anomaly associated with an attribute of a computer environment resource of the computer infrastructure. The host device is configured to correlate an object associated with the attribute of the detected anomaly with a related object of the computer infrastructure.
Sios Technology Corporation
| Method for detection of human papillomavirus|
The invention provides compositions and methods for the differential detection of high risk forms of hpv from a urine sample provided by a patient. Specifically, the invention provides primers and probes that specifically recognize and bind sequences within the e1 gene of hpv.
| Dual targeting antisense oligonucleotides as apoptotic inhibtor therapeutic compostions and methods for their use in the treatment of cancer|
Provided herein are compositions, method and uses for modulating iap activity or for the treatment of cancer. The compositions comprise dual-targeting antisense oligonucleotides (daso) for administration to a cancer cell, wherein the cancer cell may be characterized by elevated expression of one of more of birc6, ciap1 or survivin.
| 6-aryl-4-phenylamino-quinazoline analogs as phosphoinositide-3-kinase inhibitors|
The present invention relates to 6-aryl-4-phenylamino quinazolines of formula i wherein, r and r″ are as herein described. The present invention particularly relates to synthesis and anticancer and phoshpoinositide-3-kinase-α (pi3k-α) inhibitory activity.
Council Of Scientific & Industrial Research
| Shallow water anchor|
A shallow water anchor is provided. The shallow water anchor comprises a first anchor extension and a second anchor extension axially received by a housing.
Johnson Outdoors Inc.
| Preparation fluorine-doped lamellar black titanium dioxide nano material|
The method for preparing fluorine-doped lamellar black tio2 nanomaterials includes mixing a solution of tetra-n-butyl titanate, n-propanol and hydrofluoric acid together, and then stir the solutions for a period of time. The solution is transferred into an autoclave and reacts at a certain temperature for a period of time.
North China Electric Power University
| Induction of thyroid iodide-handling gene expression in human cancers|
Dual suppression of the map kinase and pi3k/akt pathways showed synergistic or greatly enhanced anti-melanoma cell effects, compared to suppression of a single pathway, including the inhibition of cell proliferation, transformation and invasion, induction of g0/g1 cell cycle arrest and, importantly, cell apoptosis. Remarkably, suppression of either pathway induces the expression of thyroid iodide-handling genes and dual suppression of the two pathways synergistically and robustly induces expression of these genes, accompanied by uptake of radioiodine in the cells.
The Johns Hopkins University
Medicament for suppressing malignant tumor metastasis
Provided are a novel medicament for suppressing or preventing the metastasis of a malignant tumor such as carcinoma, a novel treatment or prevention method for suppressing or preventing the metastasis of a malignant tumor, etc. The medicament comprises a non-peptidic angiotensin type 2 receptor agonist as an active ingredient.
Mitsubishi Tanabe Pharma Corporation
Zeaxanthin for tumor treatment
A composition comprising a pharmaceutically effective amount of zeaxanthin or its derivative for use in treating a malignant tumor and a method of using a pharmaceutically effective amount of zeaxanthin or its derivative either alone or together with one or more pharmaceutical agents for treating a malignant tumor. The tumor may be, but is not limited to breast cancer, cervix cancer, colon cancer, cutaneous melanoma, cutaneous squamous carcinoma, hepatocellular carcinoma, lung cancer, osteosarcoma, prostate cancer, and uveal melanoma.
The New York Eye And Ear Infirmary
Data usage monitoring
Systems and methods for capturing and monitoring the health, safety, and/or activity of a user are described. In one aspect, the system generates a data usage pattern for the user and monitors the user's current data usage activity to detect data usage deviations from the user's usage pattern.
Comcast Cable Communications, Llc
System and consistency based anomaly detection in an in-vehicle communication network
A system and method for providing security to a network may include monitoring, by a processor, traffic on a first and second network portions of an in-vehicle communication network; determining whether or not a first message detected on the first network portion is anomalous based on at least one of: an attribute of a second message detected on the second network portion and an absence of a second message from the second network portion over a predefined time period; and, if it is determined the first message is anomalous then performing at least one action.. .
Argus Cyber Security Ltd.
Methods and systems for api proxy based adaptive security
The invention concerns api proxy based adaptive security. The invention implements adaptive security for api servers, while avoiding data bottlenecks and maintaining client experience.
Elastic Beam, Inc.
Open-circuit detection in a switching structure
A power supply device, including: a switching structure for controlling a continuous current in an inductive load on the basis of at least one control signal of a power switch; and anomaly detection elements, generating at least one item of information about the detection of an anomaly of the open circuit type in the wiring from the load to the switching structure. The anomaly detection elements include: elements for measuring the current flowing in the inductive load; elements for comparing the measured current continuously with a threshold value; and elements for counting a time interval during which the measured current remains continuously below the threshold value, delivering the anomaly detection information if the counted time interval>a reference time interval, which is k times greater than a period of the control signal, where k>1, and if the duty cycle of the control signal>a threshold value..
Continental Automotive Gmbh
Lamination transfer films including oriented dimensionally anisotropic inorganic nanomaterials
A transfer film is provided which includes a sacrificial template layer having a first surface and a second surface opposite the first surface, wherein the second surface comprises a non-planar structured surface and a thermally stable backfill layer applied to the second surface of the sacrificial template layer, wherein the backfill layer has a structured surface corresponding with and applied to the non-planar structured surface of the sacrificial template layer. The sacrificial template layer comprises oriented dimensionally anisotropic inorganic nanomaterials and is capable of being removed from the backfill layer while leaving the structured surface of the backfill layer and the oriented dimensionally anisotropic inorganic nanomaterials substantially intact..
3m Innovative Properties Company
Systems, methods, and computer program products for detecting billing anomalies
Systems, methods, and computer program products for validating billing data and detecting anomalies in billing data are provided. In one embodiment a method is provided, the method comprising: receiving historical billing data for a customer, the historical billing data organized into a plurality of historical data sets; calculating a plurality of statistical representations of each of the plurality of historical data sets; generating a historical profile for the customer based on the plurality of statistical representations of the historical billing data; receiving current billing data for the customer; generating a current profile for the customer; comparing the current profile to the historical profile, the current profile and the historical profile being associated with the same at least one category attribute; and, based at least in part on the result of the comparison, determining whether one or more anomalies are present in the current billing data for the customer..
United Parcel Service Of America, Inc.
Anomaly detection method, program, and system
A method providing an analytical technique introducing label information into an anomaly detection model. Effective utilization of label information is based on introducing the degree of similarity between samples.
International Business Machines Corporation
Correctly identifying potential anomalies in a distributed storage system
A method for assisting evaluation of anomalies in a distributed storage system is disclosed. The method includes a step of monitoring at least one system metric of the distributed storage system.
Cisco Technology, Inc.
Interactive mechanism to view logs and metrics upon an anomaly in a distributed storage system
A method for assisting evaluation of anomalies in a distributed storage system is disclosed. The method includes monitoring at least one system metric of the system and creating a mapping between values and/or patterns of the system metric and one or more services configured to generate logs for the system.
Cisco Technology, Inc.
Method, system and predicting abnormality
A method, a system and an apparatus for predicting abnormalities are provided. A controller analyzes a plurality of command logs to obtain a predictive rule for accessing a storage device.
Information processing apparatus, controlling the same, and storage medium
An information processing apparatus divides a screen of a display unit into a first display area for displaying a list of application items for a user to select an executable application and a second display area for displaying information regarding a state of the screen or a state of the information processing apparatus, and decides a display position of the first display area when the occurrence of an anomaly is detected. The apparatus displays the list of application items in the decided first display area whose display position is decided, and displays information regarding the anomaly in the second display area.
Canon Kabushiki Kaisha
Shon as a prognostic biomarker for cancer and as a predictor of response to endocrine therapy
An estrogen-regulated gene sequence shon has been characterised, and found to be a novel oncogene in mammary carcinoma and significantly associated with estrogen and progesterone receptor expression in breast cancer. The present invention encompasses methods for predicting the responsiveness to endocrine therapy for breast cancer and providing a prognosis for disease-free and/or distant metastasis-free survival of a cancer patient..
Anti-metalloprotease antibody for diagnosis and treatment of cancers
Expression of proteolytically active, high molecular weight adam protease is relatively increased in tumour cells that also express the putative tumour stem cell marker cd133. An antibody or antibody fragment such as 8c7 monoclonal antibody may be used to selectively bind to proteolytically active, high molecular weight adam10 protease to thereby detect tumour cells and also as a therapeutic agent for treating cancers, tumours and other malignancies inclusive of leukemia, lymphoma, lung cancer, colon cancer, adenoma, neuroblastoma, brain tumour, renal tumour, prostate cancer, sarcoma and/or melanoma..
Ludwig Institute For Cancer Research Ltd
Sensor data anomaly detector
Technologies are generally described for methods and systems effective to generate an alarm for a vehicle. The methods may include receiving, by a device, a first sensor value from a first sensor for the vehicle.
Empire Technology Development, Llc
Powder distribution for laser sintering systems
There is provided improved laser sintering systems that increase the powder density and reduce anomalies of the powder layers that are sintered, that measure the laser power within the build chamber for automatic calibration during a build process, that deposit powder into the build chamber through a chute to minimize dusting, and that scrubs the air and cools the radiant heaters with recirculated scrubbed air. The improvements enable the laser sintering systems to make parts that are of higher and more consistent quality, precision, and strength, while enabling the user of the laser sintering systems to reuse greater proportions of previously used but unsintered powder..
3d Systems, Inc.
Methods and compositions for gene delivery to on bipolar cells
Disclosed are capsid-modified raav expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations that include them. Also disclosed are methods of preparing and using novel capsid-protein-mutated raav vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration of one or more diseases, disorders, or dysfunctions of the mammalian eye.
University Of Florida Research Foundation, Inc.
Duocarmycin adcs for use in treatment of endometrial cancer
The present invention relates to duocarmycin-containing antibody-drug conjugates (adcs) for use in the treatment of human solid tumours expressing her2, wherein the human solid tumour expressing her2 is endometrial cancer, in particular uterine serous carcinoma (usc). In particular, the present invention relates to duocarmycin-containing adcs for use in the treatment of endometrial cancer, notably usc, with her2 ihc 2− or 1+ and her2 fish negative tumour tissue status..
Nsd3 inhibitors for treatment of cancers
The present invention relates to the use of nsd3i inhibitors for the treatment of cancer. In particular, the present invention relates to methods, kits and compositions comprising nsd3 inhibitors to treat cancers dependent on nsd3, in particular subjects with nut midline carcinoma (nmc) and subjects with nsd3/nut or brd4/nut or brd3/nut fusion genes, as well as subjects with brd4-dependent (but nut-independent cancers).
President And Fellows Of Harvard College
Contemporaneous, heterogeneously-oriented, multi-targeted therapeutic modification and/or modulation of disease by administration of sulfur-containing, amino acid-specific small molecules
The present invention discloses and claims novel pharmaceutical compositions, methods, and kits used for the contemporaneous, heterogeneously-oriented, multi-targeted therapeutic modification and/or modulation of cellular metabolic anomalies or other undesirable physiological conditions, including cancer, where the normal cellular biochemical function and/or the expression levels of various proteins/enzymes (i.e., the target molecules) are abnormal and must be modified and/or modulated in order to treat these metabolic anomalies or other undesirable physiological conditions, including cancer. The aforementioned target molecules, by way of non-limiting example, include: anaplastic lymphoma kinase (alk), mesenchymal epithelial transition (met) kinase, the receptor tyrosine kinase (ros1), epidermal growth factor receptor (egfr), peroxiredoxin (prx), excision repair cross-complementing protein 1 (ercc1), insulin growth factor 1 receptor (igf1r), ribonucleotide reductase (rnr), tubulin, farnesyltransferase, and various other classes of proteins/enzymes.
Bionumerik Pharmaceuticals, Inc.
Fast scaning based on magnetic resonance history
During operation, a system iteratively captures mr signals of one or more types of nuclei in one or more portions of a biological lifeform based on scanning instructions that correspond to a dynamic scan plan. The mr signals in a given iteration may be associated with voxels having associated sizes at three-dimensional (3d) positions in at least a corresponding portion of the biological lifeform.
Tesla Health, Inc
Apparatus and monitoring airing events in humidors
Methods and apparatus are described herein related to an environmental monitoring system configured to avoid spoilage of goods by alerting a supervisor to hazardous conditions. A cigar humidor may be monitored by placing a cigar-shaped and cigar-sized sensor-equipped component made from metal or cedar wood inside the humidor amongst the cigars.
System and generating rules for detecting modified or corrupted external devices
Disclosed are systems and methods for generating rules for detecting modified or corrupted external devices connected to a computer system. An exemplary method includes analyzing data associated with the external device connected to the computer system based on stored data associated with one or more other devices; identifying at least one anomaly associated with the analyzed data that indicates the detected external device is modified or corrupted; generating at least one rule in response to the identified anomaly, wherein the at least one rule is based on the external device; and storing the at least one rule in a database accessible to the computer system..
Ao Kaspersky Lab
Unsupervised multisource temporal anomaly detection
In one embodiment, a computer-implemented method includes observing one or more entities by way of two or more data sources. A plurality of detection scores are computed by one or more detectors.
International Business Machines Corporation
Novel marker for detection of bladder cancer and/or inflammatory conditions of the bladder
This invention relates to the use of human neutrophil marker interleukin 8 receptor b (il8rb) for detection of bladder cancer, and more particularly to the use of el8rb for discriminating between transitional cell carcinoma of the bladder (tcc) and inflammatory conditions of the bladder.. .
Pacific Edge Limited
Methods of using anti-lgr5 antibodies
Provided herein are methods of using anti-lgr5 antibodies, for example, for treating a hedgehog-related disease including basal cell carcinoma.. .
Epha2 t-cell epitope agonists and uses therefore
Epha2 t-cell epitope are provided herein. The epitopes include peptides corresponding to specific fragments of human epha2 protein containing one or more t-cell epitopes, and conservative derivatives thereof.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education