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 Methods and systems for automated anonymous crowdsourcing of characterized device behaviors patent thumbnailMethods and systems for automated anonymous crowdsourcing of characterized device behaviors
Methods, and devices implementing the methods, use device-specific classifiers in a privacy-preserving behavioral monitoring and analysis system for crowd-sourcing of device behaviors. Diverse devices having varying degrees of “smart” capabilities may monitor operational behaviors.
Qualcomm Incorporated


 Malware detection based on training using automatic feature pruning with anomaly detection of execution graphs patent thumbnailMalware detection based on training using automatic feature pruning with anomaly detection of execution graphs
A threat detection system for detecting malware can automatically decide, without manual expert-level interaction, the best set of features on which to train a classifier, which can result in the automatic creation of a signature-less malware detection engine. The system can use a combination of execution graphs, anomaly detection and automatic feature pruning.
Threattrack Security, Inc.


 Probability-distribution-based log-file analysis patent thumbnailProbability-distribution-based log-file analysis
The current document is directed to systems, and methods incorporated within the systems, that carry out probability-distribution-based analysis of log-file entries. A monitoring subsystem within a distributed computer system uses probability-distribution-based analysis of log-file entries to detect changes in the state of the distributed computer system.
Vmware, Inc.


 Provisioning resources for datacenters patent thumbnailProvisioning resources for datacenters
Improved techniques involve creating a feedback cycle between a framework for managing many data storage arrays and system for provisioning a data storage array using real-time usage statistics from the framework. Along these lines, a multi-system provisioning tool provides an initial configuration of storage systems in a datacenter; such an initial configuration includes provisioning of logical disks for each system.
Emc Corporation


 Digital manufacturing system patent thumbnailDigital manufacturing system
A digital manufacturing system collects data from manufacturing plants, users, applications and business processes associated with a manufacturing enterprise. Anomalies in the collected data are detected and automated actions based on rules such as affecting the operation of the machines or sending messages to responsible parties are executed.
Accenture Global Services Limited


 Time based anomaly analysis in digital documents patent thumbnailTime based anomaly analysis in digital documents
A document metadata analysis system may analyze a digital document's metadata structure to identify consistencies or inconsistencies in the metadata. The analysis system may further compare a group of documents to identify consistencies or inconsistencies across multiple documents.
Pixai Us Patent Holdco, Llc


 Unsupervised anomaly-based malware detection using hardware features patent thumbnailUnsupervised anomaly-based malware detection using hardware features
Disclosed are devices, systems, apparatus, methods, products, media and other implementations, including a method that includes obtaining current hardware performance data, including hardware performance counter data, for a hardware device executing a first process associated with pre-recorded hardware performance data representative of the first process' normal behavior, and determining whether a malicious process is affecting performance of the first process based on a determination of an extent of deviation of the obtained current hardware performance data corresponding to the first process from the pre-recorded hardware performance data representative of the normal behavior of the first process.. .
The Trustees Of Columbia University In The City Of New York


 Bladder carcinoma biomarkers patent thumbnailBladder carcinoma biomarkers
Disclosed are bladder cancer protein biomarkers, methods of determining whether a patient suffers from or shows recurrence of bladder cancer or early stage bladder cancer, or late stage bladder cancer using the bladder cancer protein biomarkers, a detection system, and kits thereof. Said bladder cancer biomarkers comprise at least one of coronin-ia, apolipoprotein a-iv, semenogelin-2, gamma-synuclein and dj-1, and variants thereof..
Agency For Science, Technology And Research


 Diagnostic test for predicting metastasis and recurrence in cutaneous melanoma patent thumbnailDiagnostic test for predicting metastasis and recurrence in cutaneous melanoma
The invention as disclosed herein in encompasses a method for predicting the risk of metastasis of a primary cutaneous melanoma tumor, the method encompassing measuring the gene-expression levels of at least eight genes selected from a specific gene set in a sample taken from the primary cutaneous melanoma tumor; determining a gene-expression profile signature from the gene expression levels of the at least eight genes; comparing the gene-expression profile to the gene-expression profile of a predictive training set; and providing an indication as to whether the primary cutaneous melanoma tumor is a certain class of metastasis or treatment risk when the gene expression profile indicates that expression levels of at least eight genes are altered in a predictive manner as compared to the gene expression profile of the predictive training set.. .
Castle Biosciences, Inc.


 Method and  implantable cardiac lead integrity analysis patent thumbnailMethod and implantable cardiac lead integrity analysis
The present invention relates, generally, to scientific and medical system methods for diagnosis of implantable cardioverter defibrillator (icd) lead conductor anomalies, in particular conductor migration and externalization within an icd implantable cardiac lead. The method uses an “imaginary” component of the high frequency transmission line impedance having certain spectral changes that correspond to movements of the conductor or an “imaginary impedance”.

Inhibition of a lncrna for treatment of melanoma


This disclosure relates to the field of cancer, particularly the field of melanoma. It was found that a particular long non-coding rna (lncrna) is specifically up-regulated in melanoma (but not other tumor) cells as compared to melanocytes.
Universiteit Gent


Novel compounds as rearranged during transfection (ret) inhibitors


This invention relates to novel compounds which are inhibitors of the rearranged during transfection (ret) kinase, to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy, alone or in combination, for the normalization of gastrointestinal sensitivity, motility and/or secretion and/or abdominal disorders or diseases and/or treatment related to diseases related to ret dysfunction or where modulation of ret activity may have therapeutic benefit including but not limited to all classifications of irritable bowel syndrome (ibs) including diarrhea-predominant, constipation-predominant or alternating stool pattern, functional bloating, functional constipation, functional diarrhea, unspecified functional bowel disorder, functional abdominal pain syndrome, chronic idiopathic constipation, functional esophageal disorders, functional gastroduodenal disorders, functional anorectal pain, inflammatory bowel disease, proliferative diseases such as non-small cell lung cancer, hepatocellular carcinoma, colorectal cancer, medullary thyroid cancer, follicular thyroid cancer, anaplastic thyroid cancer, papillary thyroid cancer, brain tumors, peritoneal cavity cancer, solid tumors, other lung cancer, head and neck cancer, gliomas, neuroblastomas, von hippel-lindau syndrome and kidney tumors, breast cancer, fallopian tube cancer, ovarian cancer, transitional cell cancer, prostate cancer, cancer of the esophagus and gastroesophageal junction, biliary cancer, adenocarcinoma, and any malignancy with increased ret kinase activity.. .
Glaxosmithkline Intellectual Property Development Limited


Medical device with acoustic sensor


In at least one example, a medical device is provided. The medical device includes at least one therapy electrode, at least one electrocardiogram (ecg) electrode, at least one acoustic sensor, and at least one processor coupled with the at least one acoustic sensor, the at least one ecg electrode, and the at least one therapy electrode.
Zoll Medical Corporation


Monitoring and feedback of physiological and physical characteristics using wearable devices


Embodiments herein relate generally to sensory input for wearable devices and, more particularly, to monitor and provide feedback from wearable devices. In one example, a method for monitoring and feedback can include receiving data representing a physiological reference profile, associating the data representing the physiological reference profile with a first physiological state, acquiring data representing a physical characteristic or a physiological characteristic, or both, from one or more sensors disposed in a wearable device, correlating data representing the physical characteristic or the physiological characteristic, or both, with data representing the physiological reference profile to determine a physiological anomaly, associating the physiological anomaly with a second physiological state, and determining data representing a first amount of a remedy based on the physiological anomaly to effectuate a change from the second physiological state to the first physiological state..
Aliphcom


Systems, structures, and processes for interconnected devices and risk management


Techniques are provided that produce a risk profile consisting of a risk score and trends of risk scores across devices and sensors in a machine-to-machine (m2m) or internet of things (iot) environment. For example, a device is assigned a risk score which is based on baseline factors such as expected network packets between two devices, normal network packets, access to critical devices, authorized access requests from one device to another device, normal communications to a device, and the critical ports of a device; access to and conflicts across physical, logical, and operational systems; historical and current usage of these systems, and anomalies from normal behavior patterns.
Alert Enterprise


High temperature composite inner fixed structure


An inner fixed structure for an aircraft nacelle may comprise a nanoreinforced polyimide composite skin. The nanomaterials may increase thermal conductivity and decrease microcracking in the inner fixed structure.
Rohr, Inc.


Breast cancer biomarker signatures for invasiveness and prognosis


Microrna profiles transition from normal breast to ductal carcinoma in situ and transition to invasive ductal carcinoma (idc) and methods of use thereof are described. Methods of diagnosis and prognosis using microrna signatures to differentiate invasive from in situ carcinoma are described.
The Ohio State University


Tyrp1, a natural mirna sponge, and its use in managing human melanoma aggressiveness


The present invention relates to methods and reagents for the treatment of melanoma and/or of metastatic melanoma that directly or indirectly target tyrp1 rna transcript. The invention also relates to methods for predicting if a melanoma patient will be therapeutically responsive to such methods of treatment and reagents, and to methods for assessing the effectiveness of such methods of treatment and reagents.
Centre Hospitalier Universitaire Pontchaillou


Disease therapy by inducing immune response to trop-2 expressing cells


The present invention concerns compositions and methods of use of bispecific antibodies comprising at least one binding site for trop-2 (egp-1) and at least one binding site for cd3. The bispecific antibodies are of use for inducing an immune response against a trop-2 expressing tumor, such as carcinoma of the esophagus, pancreas, lung, stomach, colon, rectum, urinary bladder, breast, ovary, uterus, kidney or prostate.
Ibc Pharmaceuticals, Inc.


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Antibodies for treatment of cancer expressing claudin 6


The present invention provides antibodies useful as therapeutics for treating and/or preventing diseases associated with cells expressing cldn6, including tumor-related diseases such as ovarian cancer, lung cancer, gastric cancer, breast cancer, hepatic cancer, pancreatic cancer, skin cancer, malignant melanoma, head and neck cancer, sarcoma, bile duct cancer, cancer of the urinary bladder, kidney cancer, colon cancer, placental choriocarcinoma, cervical cancer, testicular cancer, and uterine cancer.. .
Johannes Gutenberg-universitat Mainz


Costimulatory b7-h1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target


The invention features methods of diagnosis by assessing b7-h1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with b7-h1-receptor interaction, methods of selecting candidate subjects likely to benefit from cancer immunotherapy, and methods of inhibiting expression of b7-h1.. .
Mayo Foundation For Medical Education And Research


Pyrrolo pyrimidine derivative


A compound represented by the general formula (1) has a pyridone ring structure introduced into a pyrrolo pyrimidine skeleton, so that the compound has a strong axl inhibitory activity. Consequently, the compound can be used as a therapeutic agent for axl-related diseases including cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases..
Ono Pharmaceutical Co., Ltd.


Polycyclic inhibitors of cyclin-dependent kinase 7 (cdk7)


The present invention provides novel compounds of formula (i), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, lymphoma, melanoma, multiple myeloma, breast cancer, ewing's sarcoma, osteosarcoma, brain cancer, neuroblastoma, lung cancer), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject.
Dana-farber Cancer Institute, Inc.


Heteromaromatic compounds useful for the treatment of prolferative diseases


The present invention provides novel compounds of formula (i) and formula (ii), and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject.
Syros Pharmaceuticals, Inc.


Heteroaromatic compounds useful for the treatment of prolferative diseases


The present invention provides novel compounds of formula (i), and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject.
Dana-farber Cancer Institute, Inc.


Collaborative robot for visually inspecting an aircraft


A device for visually inspecting the external surfaces of an aircraft includes an inspection area to receive an aircraft, at least one visual inspection robot, and a control center. A movable platform of the robot supports a turret having an observation unit.
Airbus Group Sas


Space, luminous ceiling conducting photodynamic therapy


A space for conducting photodynamic therapy (pdt) for treatment of skin diseases, especially for treatment of superficial skin tumors such as actinic keratoses, basal cell carcinomas, and initial carcinomas, wherein an active ingredient is applied to a skin area to be treated in order to form porphyrins and irradiation with light is conducted to form singlet oxygen based on the porphyrins in order to destroy diseased skin cells, wherein the space has side walls, a ceiling, and a floor, as well as at least two lighting fixtures, which are separated from one another by at least 50 cm and illuminate at least a subregion of the space, wherein there is an illuminance of at least 8,000 lux at every point in the subregion and the subregion has horizontal dimensions of at least 1 m2 and a vertical height of at least 40 cm. This invention also relates to a luminous ceiling system and method for conducting pdt..
Swiss Red Ag


T cell receptors directed against the preferentially expressed antigen of melanoma and uses thereof


The technology relates in part to compositions and methods for inducing an immune response against the preferentially expressed antigen of melanoma (prame). Provided are methods for treating hyperproliferative diseases by inducing an immune response against prame antigen; the immune response may be induced by specifically targeting prame-expressing cells using t cell receptors directed against prame..
Leiden University Medical Center


Modular head assembly


A low profile orthopedic device is used to fix and stabilize bones to correct anomalies in skeletal structure occurring naturally or by trauma. Bone screws are screwed into bones by application of torque.
Spinal Llc


Interactive virtual care


An interactive virtual care system may include a user sensory module to acquire multi-modal user data related to user movement. A data analysis module may compare the multi-modal user data to predetermined historical user data and/or statistical norm data for users to identify an anomaly in the user movement..
Accenture Global Services Limited


Anomaly detection based on cluster transitions


Systems and methods may include receiving first data of components, which may represent performance characteristics of the components at a first time. The systems and methods may include performing a first cluster analysis of the first data to identify clusters of the components with similar characteristics.
Ca, Inc.


Anomaly detection in industrial communications networks


An anomaly detection system installed in a plant communications network detects unexpected changes or anomalies in the traffic patterns over the communications network to detect infected or potentially infected nodes. The anomaly detection system includes various data collection modules at each of the nodes of the network which operate to view the message traffic into and out of the node and to generate metadata pertaining to the message traffic.
Fisher-rosemount Systems, Inc.


Behavioral analysis to automate direct and indirect local monitoring of internet of things device health


The disclosure generally relates to behavioral analysis to automate monitoring internet of things (iot) device health in a direct and/or indirect manner. In particular, normal behavior associated with an iot device in a local iot network may be modeled such that behaviors observed at the iot device may be compared to the modeled normal behavior to determine whether the behaviors observed at the iot device are normal or anomalous.
Qualcomm Incorporated


Switching power supply device


A switching power supply device having a synchronous rectifier ic on a secondary side, responds to an anomaly on a primary side based on detecting an occurrence of the anomaly on the secondary side. When a secondary side synchronous rectifier ic detects an anomaly, a current is output from the anomaly-time current output terminal of the secondary side synchronous rectifier ic.
Fuji Electric Co., Ltd.


Optical amplifier


The present embodiment relates to an optical amplifier which can perform an amplification operation equivalent to a normal operation even with an increase of dark current in a pd forming a part of a light detection circuit for monitoring signal light as an amplification object. In the optical amplifier, a detection controller performs an anomaly determination on a light detection circuit due to an increase of dark current in the pd based on a difference between temporal change amounts of a signal component of a voltage of output signal from a light receiving unit including the pd, and a voltage component in a high frequency region included in the signal component.
Sei Optifrontier Co., Ltd.


Detecting road condition changes from probe data


Systems, methods, and apparatuses are disclosed for identifying anomalies or changes in road conditions on a roadway location. An initial low rank data matrix of initial vehicle probe data at a plurality of different times for a roadway location is provided, where the initial low rank data matrix represents a baseline of road conditions for the roadway location.
Here Global B.v.


Multi-component and mixed-reality simulation environments


Systems and methods may include receiving real-time data from real components operating in a real-world environment. The systems and methods may further include generating a virtual representation of the real components based on the real-time data received from the real components and historical data associated with the real components.
Ca, Inc.


Shopping facility assistance systems, devices, and methods to identify security and safety anomalies


A central computer system is configured to simultaneously task various ones of a plurality of motorized transport units to temporarily attach to a corresponding mobile item container and to move the temporarily-attached mobile item container in a retail shopping facility in correspondence to the movement of an authorized consumer while also receiving and analyzing video input provided by video cameras that are included with at least some of the motorized transport units to identify security and safety anomalies in the retail shopping facility. By one approach, the central computer system identifies security and safety anomalies in the retail shopping center by characterizing contents of images as being either expected or unexpected and as being either potentially harmful or not potentially harmful.
Wal-mart Stores, Inc.


Estimating temperature values at field level based on less granular data


A method for temperature interpolation is provided. In an embodiment climatology records and temperature observations are received by a weather computing system over a network from an outside source.
The Climate Corporation


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Anomaly detection method, program, and system


A method providing an analytical technique introducing label information into an anomaly detection model. The method includes the steps of: inputting measurement data having an anomalous or normal label and measurement data having no label as samples; determining a similarity matrix indicating the relationship between the samples based on the samples; defining a penalty based on the similarity matrix and calculating parameters in accordance with an updating equation having a term reducing the penalty; and calculating a degree of anomaly based on the calculated parameters.
International Business Machines Corporation


Anomaly detection method, program, and system


A method providing an analytical technique introducing label information into an anomaly detection model. The method includes the steps of: inputting measurement data having an anomalous or normal label and measurement data having no label as samples; determining a similarity matrix indicating the relationship between the samples based on the samples; defining a penalty based on the similarity matrix and calculating parameters in accordance with an updating equation having a term reducing the penalty; and calculating a degree of anomaly based on the calculated parameters.
International Business Machines Corporation


Costimulatory b7-h1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target


The invention features methods of diagnosis by assessing b7-h1 expression in a tissue from a subject that has, or is suspected of having, cancer, methods of treatment with agents that interfere with b7-h1-receptor interaction, methods of selecting candidate subjects likely to benefit from cancer immunotherapy, and methods of inhibiting expression of b7-h1.. .
Mayo Foundation For Medical Education And Research


Human fibrolamellar hepatocellular carcinomas (hfl-hccs)


The present disclosure provides a model of human fibrolamellar hepatocellular carcinoma (fl-hcc) cells maintained as a transplantable tumor line in a host and a method to establish a transplantable human fl-hcc tumor line. Methods of ex vivo cultures of the fl-hcc are provided.
University Of North Carolina At Chapel Hill


Antibody therapeutics that bind jag1


There is disclosed compositions and methods relating to or derived from anti-jag1 antibodies. More specifically, there is disclosed fully human antibodies that bind jag1, jag1-binding fragments and derivatives of such antibodies, and jag1-binding polypeptides comprising such fragments.
Sorrento Therapeutics, Inc.


Combination therapy


The present invention relates to a combination therapy of propane-1-sulfonic acid {3-[5-(4-chloro-phenyl)-1h-pyrrolo [2,3-b] pyridine-3-carbonyl-2,4-difluoro-phenyl]-amide}, or a pharmaceutically acceptable salt thereof, and an interferon for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example, colorectal cancer, melanoma, and thyroid cancer. In particular, the present invention relates to such a therapy wherein the interferon is peginterferon alfa-2a and the disorder is melanoma containing the v600e b-raf mutation..
Hoffmann-la Roche Inc.


Combination liposomal pharmaceutical formulations


Docetaxel and doxorubicin can be formulated in liposomal pharmaceutical compositions. In various embodiments, the pharmaceutical compositions include (i) a first liposome type comprising a first lipid layer comprising an unsaturated phospholipid, cholesterol or a cholesterol derivative, dc-cholesterol, a cationic lipid, and preferably a pegylated phospholipid, and a first active pharmaceutical ingredient (api) comprising docetaxel in the first lipid layer; and (ii) a second liposome type comprising a second lipid layer, an aqueous interior, and a second api comprising doxorubicin crystallized in the aqueous interior, (iii) where the first liposome type does not comprise doxorubicin and the second liposome type does not comprise docetaxel.
Cureport, Inc.


System and methods for computer network security involving user confirmation of network connections


Systems and methods for detecting anomalies in network traffic and providing notification to the users of the computers that generated the network traffic for confirmation of the activities that resulted in the network traffic are described herein. According to particular embodiments, the system is configured to collect data regarding network activity (e.g., via sensors), generate inquiries to users regarding that activity, receive the user's response to those inquiries, and provide the user's response along with the network activity to a security analyst..
Lancope Llc


System, method, apparatus and machine-readable media for enterprise wireless calling


Embodiments include receiving one or more packets of a wi-fi calling session via a secure tunnel from a user device, where the user device is connected to a source network via a wi-fi access point. Embodiments also include determining whether the wi-fi calling session is a threat based, at least in part, on identifying an anomaly of at least one packet of the one or more packets.
Cisco Technology, Inc.


Classification of detected network anomalies using additional data


A network anomaly detector detects a network anomaly by monitoring a communication network and provides an indication of the detected network anomaly to a network anomaly analyzer. The network anomaly analyzer receives the indication of the detected network anomaly and, on the basis of data representing the detected network anomaly and additional data, e.g., from outside the communication network, performs classification of the detected network anomaly.
Telefonaktiebolaget L M Ericsson (publ)


Systems, methods, and computer-readable media for electronic report tracking


Exemplary embodiments are disclosed herein for processing one or more sheets of sheet material in a deposit include various systems and processes. The systems and processes include receiving a sheet in a sheet-accepting device.
Giesecke & Devrient America, Inc.


Systems, methods, and computer-readable media for electronic report tracking


Exemplary embodiments are disclosed herein for processing one or more sheets of sheet material in a deposit include various systems and processes. The systems and processes include receiving a sheet in a sheet-accepting device.
Giesecke & Devrient America, Inc.


Systems, methods, and computer-readable media for reconciling deposits


Exemplary embodiments are disclosed herein for processing one or more sheets of sheet material in a deposit include various systems and processes. The systems and processes include receiving a sheet in a sheet-accepting device.
Giesecke & Devrient America, Inc.


Large-scale anomaly detection with relative density-ratio estimation


In one embodiment, a set of training data consisting of inliers may be obtained. A supervised classification model may be trained using the set of training data to identify outliers.
Yahoo! Inc.


Return oriented programming attack detection via memory monitoring


Aspects include computing devices, systems, and methods for implementing detecting return oriented programming (rop) attacks on a computing device. A memory traversal map for a program called to run on the computing device may be loaded.
Qualcomm Incorporated


Contextual graph matching based anomaly detection


Contextual graph matching based anomaly detection may include evaluating computer-generated log file data to create a master directed graph that specifies known events and transitions between the known events. The master directed graph may be processed to determine a plurality of decomposed master graph walks.
Accenture Global Services Limited


Methods and devices for nasopharyngeal carcinoma screening


Methods and devices for nasopharyngeal carcinoma screening are disclosed. The method comprises providing a nasopharyngeal sample from a subject, isolating dna from the sample, amplifying and detecting at least one ebv target sequence from the dna using real-time pcr, wherein a real-time pcr cycle threshold number of less than or equal to 31.5 is indicative of the subject having nasopharyngeal carcinoma or a risk of developing nasopharyngeal carcinoma.
Advance Sentry Corporation


Systems and methods for formation and harvesting of nanofibrous materials


A system that receives nanomaterials, forms nanofibrous materials therefrom, and collects these nanofibrous materials for subsequent applications. The system is coupled to a chamber that generates nanomaterials, typically carbon nanotubes produced from chemical vapor deposition, and includes a mechanism for spinning the nanotubes into yarns or tows.
Nanocomp Technologies, Inc.


Surface mechanical attrition treatment (smat) methods and systems for modifying nanostructures


Described herein are systems and methods for performing a surface mechanical attrition treatment (smat) to the surface of a variety of materials including thin films, nanomaterials, and other delicate and brittle materials. In an aspect, a surface of a material is modified to a modified surface and from an original state to a modified state, wherein the modified state comprises a physical modification, a chemical modification, or a biological modification.
City University Of Hong Kong


Processes for producing and treating thin-films composed of nanomaterials


Processes for producing and treating thin-films comprising nanomaterials are provided. A process of producing a transparent conducting film includes printing nanomaterials on a substrate, and directing a laser beam onto the nanomaterials to weld junctions between the nanomaterials.
Purdue Research Foundation


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Method for detecting and localizing insulation failures of implantable device leads


The invention relates to a method and apparatus for diagnosis of conductor anomalies, such as insulation failures, in an implantable medical device, such as an implantable cardioverter defibrillator (icd), a pacemaker, or a neurostimulator. Insulation failures are detected and localized by identifying changes in electrical fields via surface (skin) potentials.
Lambda Nu Technology Llc


Galectin-3 as immunological target


Annexina2 (anxa2), a member of the annexin family of calcium-dependent, phospholipid binding proteins, is one of a panel of identified antigens recognized by the post-vaccination sera of patients who demonstrated prolonged disease-free survival following multiple vaccinations. Annexina2 is abundantly expressed in pancreatic adenocarcinomas and cell surface/membrane annexina2 increases with the progression from premalignant lesions to invasive pancreatic adenocarcinomas.
The Johns Hopkins University


Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (hcc) and other cancers


The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer.
Immatics Biotechnologies Gmbh


Method of treating a malignancy in a subject and a pharmaceutical composition for use in same


There is a disclosed a method of killing abnormal cells such as malignant cells including melanoma cells, using a virus recognising at least one of a cell adhesion molecule and a complement regulatory protein. The virus may be a member of the picornaviridae family.
Viralytics Limited


Pkc delta inhibitors for use as therapeutics


The invention is directed to compounds that are specific inhibitors of pkc delta, and methods and compositions for the treatment and prevention of cancers and other disorders. Compositions comprising compounds of the invention are used to treat cancers such as, for example, carcinoid and neuroendocrine tumors, malignant melanomas, pancreatic, gastrointestinal and lung cancers.





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