|| List of recent Noma-related patents
|System for automated computer support|
Systems and methods for providing automated computer support are described herein. One described method comprises receiving a plurality of snapshots from a plurality of computers, storing the plurality of snapshots in a data store, and creating an adaptive reference model based at least in part on the plurality of snapshots.
|Amino acid sequence for inhibiting ptx3 to treat nasopharyngeal carcinoma|
The invention relates to an amino acid sequence for inhibiting ptx3 to treat nasopharyngeal carcinoma. It can be used to inhibit ptx3 from promoting the migration and invasion of nasopharyngeal carcinoma cells, promoting angiogenesis and inhibiting macrophage phagocytosis to further treat nasopharyngeal carcinoma..
|Methods and compositions for diagnosis and prognosis of renal injury and renal failure|
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a one or more assays configured to detect a kidney injury marker selected from the group consisting of growth/differentiation factor 2, catalase, vascular endothelial growth factor c, and melanoma-derived growth regulatory protein as diagnostic and prognostic biomarkers in renal injuries..
|Genetic marker for detection of human papillomavirus|
The invention provides compositions and methods for the differential detection of high risk forms of hpv from a urine sample provided by a patient. Specifically, the invention provides primers and probes that specifically recognize and bind sequences within the e1 gene of hpv.
|Identifying anomalies in original metrics of a system|
An anomalous component within a processing system is identified. One or more transformed metrics of a processing system being monitored are analyzed, and an anomaly in the processing system is detected.
|Detecting electricity theft via meter tampering using statistical methods|
A method for detecting anomalous energy usage of building or household entities. The method applies a number of successively stringent anomaly detection techniques to isolate households that are highly suspect for having engaged in electricity theft via meter tampering.
|Detecting electricity theft via meter tampering using statistical methods|
A system and method for detecting anomalous energy usage of building or household entities. The method applies a number of successively stringent anomaly detection techniques to isolate households that are highly suspect for having engaged in electricity theft via meter tampering.
|Computer readable medium for enabling a computer to carry out provision of information on hepatocellular carcinoma and marker and kit for obtaining information on hepatocellular carcinoma|
The above object is achieved by obtaining the analysis result on methylation status of a cpg site located in a promoter region of at least one gene selected from celf6 and rnf135 in a dna sample derived from the subject and providing information on hepatocellular carcinoma in the subject based on the resulting analysis result.. .
|Automated doppler pulse cycle selection|
A device (308) is configured for examining pulsatile flow, for deriving, based on the examined flow, spectral characteristics and for, based on the derived characteristics, determining which one or more pulse cycles are to be selected as representative of the flow. The cycles selected can be consecutive and amount to a predetermined number of cycles, such as five.
|Spiroindoline derivatives as gonadotropin- releasing hormone receptor antagonists|
Spiroindoline derivatives, process for their preparation and pharmaceutical compositions thereof, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially sex-hormone-related diseases in both men and women, in particularly those selected from the group of endometriosis, uterine fibroids, polycystic ovarian disease, hirsutism, precocious puberty, gonadal steroid-dependent neoplasia such as cancers of the prostate, breast and ovary, gonadotrope pituitary adenomas, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hypertrophy, contraception and infertility (e.g., assisted reproductive therapy such as in vitro fertilization). The present application relates in particular to spiroindoline derivatives as gonadotropin-releasing hormone (gnrh) receptor antagonists..
|Prognostic assay for squamous cell lung carcinoma|
Methods for predicting clinical outcome for a human subject diagnosed with squamous cell lung carcinoma using a panel of molecular markers that includes cdkn2a and ccnd1. The markers are related to the subject's increased likelihood of a negative clinical outcome..
|Automatic analyzer and method for detecting measurement value abnormalities|
An automatic analyzer detects measurement value abnormalities stemming from reaction process anomalies caused by the presence of foreign matter or bubbles. It is determined whether the results of concentration calculation based on light quantity data from multiple target detectors each fall within an applicable determination range.
|Methods and compositions for somatic cell proliferation and viability|
Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding protein isolated from a medium conditioned by growth of pluripotent stem cells, such as, human embryonic stem cells, human embryonic carcinoma cells.
|Method for checking the self-healing process carried out by the immune system of a test subject infected with human papilloma virus|
A method and device for checking the self-healing process carried out by the immune system of a test subject infected with human papillomavirus (hpv) using one or more cell-containing samples taken from the test subject, to prevent the formation of an hpv-induced carcinoma. The method involves: (1) determining whether hpv with at least one hpv-specific stimulus molecule, stimulating the test subject's immune system, is contained in at least one of the samples; (2) determining whether innate hpv antibodies with the stimulus molecule are in the sample or at least one of the other samples; (3) analyzing results from (1) and (2) to determine whether the self-healing process has started based on the presence of the stimulus molecule and/or the antibodies..
|Combination therapy to prevent dcis formation and progression to breast cancer|
A method of treating a ductal carcinoma in situ (dcis) lesion in a subject in need thereof is disclosed. The method comprises administering to the subject a therapeutically effective amount of a first agent capable of down-regulating activity and/or expression of at least one component participating in a notch pathway, and a second agent capable of down-regulating an activity and/or expression of her2, thereby treating the dcis lesion..
|Computer implemented method for tracking and checking measures and computer programs thereof|
A computer implemented method for tracking and checking measures and computer programs thereof. A master node receiving from a plurality of slaves nodes messages related with measures generated by the slaves nodes, the method including: capturing, a traffic driver unit, the messages sent by the slaves nodes and further sending them to a monitor unit; analyzing, the monitor unit, the received messages so as to detect, by a behavioral learning technique, anomalies in the messages; when an anomaly is detected, sending, the monitor unit, the detected anomaly to a regenerator unit for regenerating at least the detected anomaly by a prediction technique; and injecting, said traffic drive unit, measures regenerated by the regenerator unit to the transport network..
|Separation of luminescent nanomaterials|
The invention relates to analysis of photon upconversion luminescent inorganic lanthanide-doped nanomaterials and/or separation and/or purification of them from other materials such as biomolecules and/or chemicals used e.g. For bioconjugation in preparation of reagents based on upconverting lanthanide nanoparticles for bioanalytical assays.
|System and method for alleviating sleep apnea|
A system and method for controlling a device to alleviate sleep apnea comprises determining whether a user of the device is asleep by a microcontroller operatively connected to the device. Using a sensor operatively connected to the microcontroller, it is determined whether a breathing anomaly of the user is detected while the user is asleep.
|Device and system for ultrasonic inspection|
This disclosure describes embodiments of a probe assembly and an inspection system for ultrasonic inspection. Designs for the probe assembly package components to fit into a bore of a hollow target.
|Device for ultrasonic inspection|
This disclosure describes embodiments of a probe device that can replace the multiple probes now required to perform inspection of hollow targets. These embodiments can generate acoustic waves as both shear waves and compression waves.
|Mirnas useful to reduce lung cancer tumorigenesis and chemotherapy resistance and related compositions and methods|
Disclosed are compositions, such as nucleic acids, vectors, cells, animal models and the like, useful to reduce tumor growth, cancer cell migration and various other cancer pathologies associated with egfr (epidermal growth factor receptor) and met (the receptor tyrosine kinase for hepatocyte growth factors) dyregulation, particularly in non-small cell lung carcinoma.. .
|Anomaly diagnosis system|
Any one of ecus that are operating detects a present power supply voltage repeatedly. When the voltage detected at the present time is changed from the voltage detected at the previous time, a difference is calculated as a variation value and the repeatedly calculated variation values are integrated to provide a voltage variation integrated value.
|Nanofluids and methods of use for drilling and completion fluids|
Nanomaterial compositions are useful for applications in drilling and completion fluids as enhancers of electrical and thermal conductivity, emulsion stabilizers, wellbore strength improvers, drag reduction agents, wettability changers, corrosion coating compositions and the like these nanomaterials may be dispersed in the liquid phase in low volumetric fraction, particularly as compared to corresponding agents of larger size. Nanofluids (fluids containing nano-sized particles) may be used to drill at least part of the wellbore.
|Methods of detecting lung cancer|
Methods of detecting lung cancer, such as non-small cell lung cancer, including squamous cell carcinoma and adenocarcinoma, are provided. Methods of detecting changes in the levels of one or more small rnas associated with lung cancer are also provided.
|Methods for controlling heat generation of magnetic nanoparticles and heat generating nanomaterials|
The present invention relates to a method for controlling heat generation of a magnetic nanomaterial, comprising the steps of: (a) mixing (i) a nanomaterial precursor comprising a metal precursor material and a predetermined amount of a zinc precursor with (ii) a reaction solvent; and (b) preparing a zinc-containing magnetic nanomaterial from the mixture of step (a) comprising a zinc doped metal oxide nanomaterial matrix; and wherein a specific loss power of the zinc-containing magnetic nanomaterial is varied depending an amount of zinc to be doped, whereby the heat generation of the magnetic nanomaterial is controlled. In addition, the present invention relates to a heat-generating nanoparticle and a composition for hyperthermia.
|Combinatorial methods and compositions for treatment of melanoma|
The invention relates to combining targeted therapies with selected chemotherapeutics for the treatment of melanoma. The invention provides a method for inducing apoptosis in a melanoma tumor cell by reducing akt3 activity, a method for inducing apoptosis in a melanoma tumor cell comprising contacting a melanoma tumor cell with an agent that reduces akt3 activity to restore normal apoptotic sensitivity to a melanoma tumor cell, allowing a lower concentration of chemotherapeutic agents resulting in decreased toxicity to a patient.
|Predictive biomarker of survival in the treatment of renal cell carcinoma|
Methods and compositions are disclosed for predicting and treating the clinical benefit to a human renal cell carcinoma patient prior to their treatment with a vegfr inhibitor and an ang2 inhibitor.. .
|Methods to reduce polyposis and colorectal cancer|
Methods for reducing or inhibiting polyposis or colorectal cancer are provided. The methods comprise administering to a mammal a bacterium modified to decrease the display of lipoteichoic acid on the cell surface.
|Orientation imaging using wide angle convergent beam diffraction in transmission electron microscopy|
Methods of orientation imaging microscopy (oim) techniques generally performed using transition electron microscopy (tem) for nanomaterials using dynamical theory is presented. Methods disclosed may use a wide angle convergent beam electron diffraction for performing oim by generating a diffraction pattern having at least three diffraction discs that may provide additional information that is not available otherwise..
|Cooking appliance for processing and preparing foods|
A cooking appliance for processing and preparing foods that includes a base structure (48) on which a support suitable for holding a container (2) containing foods to be processed is assembled, a motorized driving device suitable for rotating a detachable stirring or cutting device inside the container (2), an electronic circuit for powering and controlling the driving device and a heat energy transferring device which is controlled by an appliance microcontroller, and a dedicated computing device (85) integrating a user interface and a telecommunication interface, which, depending on the instructions provided by a user, is suitable for at least sending instructions containing cooking parameters and/or programs to the appliance microcontroller through a data bus and for displaying any anomaly detected by the appliance microcontroller through a multifunction touch screen.. .
|Scalable log analytics|
Large amounts of unstructured log data generated by software and infrastructure components of a computing system are processed and analyzed in real time to identify anomalies and potential problems within the computing system. A log analytics module reduces both the volume and level of detail of log data by first classifying log messages into message types based on their content similarity.
|Systems and methods for asynchronous schema changes|
This disclosure provides systems and methods for updating database servers with schema changes to avoid concurrency anomalies. The system may receive a snapshot of a table to be updated with a new schema, wherein the snapshot is taken at a given time, and wherein the table includes a number of rows.
|Method and apparatus for normalizing and predicting time series data|
A computer implemented method and apparatus for normalizing and predicting time series data. The method comprises accessing collected data comprising a plurality of intervals; defining a variation for each interval in the plurality of intervals, wherein each variation is a cost value; clustering the cost values, wherein clustering identifies anomalies in the collected data; correcting the anomalies in the collected data; and creating a set of normalized data from the corrected data..
|Systems and methods for data mining and modeling|
Techniques for prediction of financial instrument returns, identifying statistical history, the discovery of pricing anomalies, and financial instrument visualization are disclosed. In one particular exemplary embodiment, the techniques may be realized as a method for identifying financial instrument returns and pricing anomalies including matching, using at least one computer processor one or more portions of current market data associated with a financial instrument with historical market data, averaging outcomes of matched historical market data, and providing a probabilistic outcome for financial instrument returns, pricing anomalies, or other metrics based on the matched historical market data and the current market data.
|Data analytics platform using social network and web data to identify a pattern or anomaly among relevant events and entities|
Disclosed is a technique that intakes data from an initial court case and relevant court cases to identify relevant events and entities (e.g. An individual or an organization).
|Method for reducing expression of downregulated in renal cell carcinoma in malignant gliomas|
The present invention relates to novel compositions and therapeutic methods for the treatment of cancer, in particular malignant glioma. The compositions include antisense oligonucleotides or rnas or vectors encoding them which reduce expression of downregulated in renal cell carcinoma (drr) in tumor cells, and inhibit malignant glioma cell invasion..
|Compositions and methods for treating cancer|
The instant invention provides a method of treating a cancer, selected from the group consisting of breast cancer, melanoma, colorectal cancer, non-small cell lung cancer and ovarian cancer, by administering a combination of a wee1 inhibitor and a chk1 inhibitor, wherein the wee1 inhibitor is mk-1775 or a pharmaceutically acceptable salt thereof, or mk-3652 or a pharmaceutically acceptable salt thereof, and the chk1 inhibitor is mk-8776 or a pharmaceutically acceptable salt thereof, or sch900444 or a pharmaceutically acceptable salt thereof.. .
|Diagnostic tests for predicting prognosis, recurrence, resistance or sensitivity to therapy and metastatic status in cancer|
The present invention describes a method utilizing a set of genes or gene products whose altered expression in cancer tissue, particularly head and neck cancer and other carcinomas, or its adjacent normal tissues predicts (a) probability of recurrence in time after treatment (b) sensitivity or resistance to therapies or (c) probability of metastasis at the time of initial discovery of the tumor. Furthermore, the invention describes methods of determining the molecular signature in tumor tissues, tissues adjacent to the tumor, or in saliva by using dna microarray techniques, quantitative real-time pcr, immunohistochemistry or other methods that are used for determining gene or gene product expression levels..
|Biomarkers of high-grade serious ovarian carcinomas|
The present disclosure provides biomarkers useful for determining the prognosis of conditions such as ovarian cancer. The presently disclosed subject matter provides angiogenic biomarkers and methods and compositions for predicting overall survival (os) in women with high-grade serious carcinomas (hgscs).
|Composition for targeting dendritic cells|
The present invention relates to a composition for targeting dendritic cells. In particular, the present invention relates to a composition comprising: a) one or more antigens; b) an anti-dc-sign immunoglobulin single variable domain; and c) a carrier which carries a) and b).
|Therapeutic combinations and methods of treating melanoma|
The invention provides therapeutic combinations of anti-etbr antibodies and map kinase inhibitors and methods of using the same to treat melanoma.. .
|Anomaly detector and environmental tester including the same|
A controlling section 41 receives determined temperature and humidity values, set temperature and humidity values, a heating electric power value, and a humidifying electric power value from a body controller 30. A comparison and determination section 46 compares the heating electric power value and the humidifying electric power value with respective predetermined reference electric power values, and when at least one of the heating electric power value or the humidifying electric power value is less than a corresponding one of the reference electric power values, the comparison and determination section 46 outputs an anomaly signal indicating that the cooling capacity of a refrigeration apparatus 22 has been reduced..
|Piracy prevention in digital rights management systems|
A method in a multimedia device (130) including obtaining protected content having a limited exercisable right associated therewith, obtaining an extension of the limited exercisable right when a condition is satisfied, for example, when the device enters a drm system different than the drm system from which the protected content originated, wherein the extension of the limited exercisable right is obtained from an entity other than the multimedia device, for example, from an anomaly detector.. .
|Method for vehicle intrusion detection with mobile router|
A method of operating a mobile router installed in a vehicle is provided. The vehicle comprises a vehicle network bus coupled to a plurality of electronic control units.
|Crc counter normalization|
The ability to accurately and efficiently calculate and report communication errors is becoming more important than ever in today's communications environment. More specifically calculating and reporting crc anomalies in a consistent manner across a plurality of communications connections in a network is crucial to accurate error reporting.
|Multipath data streaming over multiple wireless networks|
Embodiments described herein relate to real-time streaming of large quantities of time critical data over multiple distinct networks from a wireless communications device. More specifically, embodiments described herein may address challenges and problems of maintaining consistent data reception quality when faced with the anomalies of a moving sender that is sending data using a relatively unstable radio frequency (rf) method.
Nodes of a database service may receive a read request to perform a read of a record stored by the database service and a transaction request to perform a transaction to the record. First and second indications of time may be associated with the read and transaction, respectively.
|Detecting occurrence of abnormality|
A method, apparatus and computer program for detecting occurrence of an anomaly. The method can exclude arbitrariness and objectively judge whether a variation of a physical quantity to be detected is abnormal or not even when an external environment is fluctuating.
|Tyrosine, serine and threonine phosphorylation sites|
The invention discloses 155 novel phosphorylation sites identified in carcinoma and leukemia, peptides (including aqua peptides) comprising a phosphorylation site of the invention, antibodies specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.. .
|Solution based polymer nanofiller-composites synthesis|
A solution based polymer nanofiller composite processing method to improve mechanical, electrical, thermal and/or chemical properties. The solution based synthesis method may include the steps of surface functionalizing carbon nanomaterials and dissolving a polymer in a solvent.
|Molecular signatures of invasive cancer subpopulations|
Carcinomas typically invade as a cohesive multicellular unit, a process termed collective invasion. It remains unclear how different subpopulations of cancer cells contribute to this process.
|Compositions and methods for screening and treatment of sturge-weber syndrome, klippel-trenaunay-weber syndrome, and port-wine stains (pwss)|
Compositions and methods for treatment of sturge-weber syndrome, klippel-trenaunay-weber syndrome, port-wine stains and related neurocutaneous disorders are provided. Cell lines having the somatic mutation gnaq p.arg183gln amino acid substitution, which was found to be the cause of port-wine stains (prevalence 1 in 300) and sturge-weber syndrome are also provided.
|Polypeptides targeting glycosylated muc2 proteins, methods of synthesis, their nucleic acids and uses thereof|
The invention relates to polypeptides, defined through a consensus sequence, having a length from 10 to 80 amino-acid residues, and whose polypeptidic sequence comprises or consists of the consensus sequence p1(xa)p3(xb)p5(xc)p6(xd)p7 (seq id no: 1), presenting specific patterns. The polypeptides of the invention target glycosylated muc2 proteins.