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|| List of recent Neublastin-related patents
|Compositions and methods for increasing vascularization|
Disclosed are methods of increasing vascularization in a tissue by administering a neublastin polypeptide to a mammal exhibiting impaired or inadequate blood flow in the tissue. The methods can be used to in the treatment or prevention of a disorder characterized by impaired or inadequate blood flow or to increase vascularization in an organ that has been transplanted into a subject..
|Treatment using neublastin polypeptides|
The invention relates to treatments of neuropathic pain, including tactile allodynia, and to treatments for reducing loss of pain sensitivity associated with neuropathy. The present treatments involve the use of neublastin (nbn) polypeptides..
|Novel neurotrophic factors|
The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as methods of making and methods of using the same.. .
Variant neublastin polypeptides having substitutions at selected amino acid residues are disclosed. Substitution at one or more selected amino acid residues decreases heparin binding and increases serum exposure of variant neublastin polypeptides.
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Neublastin topics: Neublastin, Polypeptide, Transplant, Neuropathy, Treatments, Neuropathic Pain, Neurotrophic Factors, Nucleic Acids, Nucleic Acid, Antibodies, Amino Acid
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