Images List Premium Download Classic

Neoplasm

Neoplasm-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


loading
Method of diagnosing neoplasms
Commonwealth Scientific And Industrial Research Organisation
April 12, 2018 - N°20180100200

The present invention relates generally to nucleic acid molecules, the rna and protein expression profiles of which are indicative of the onset, predisposition to the onset and/or progression of a neoplasm. More particularly, the present invention is directed to nucleic acid molecules, the expression profiles of which are indicative of the onset and/or progression of a large intestine ...
Compositions and methods for prognosis and treatment of neoplasm
Novazoi Theranostics, Inc.
April 05, 2018 - N°20180095070

A protocol for assessing the prognosis for a patient diagnosed with a neoplasm or suspected of having a neoplasm is provided herein. The protocol involves the steps of determining a mitotic cells to proliferating cells ratio (m:p ratio) in a neoplastic tissue sample obtained from the patient and producing a prognosis for the neoplasm based on the m:p ...
Anti-cd303 monoclonal antibodies
Laboratoire Francais Du Fractionnement Et Des Biotechnologies
March 29, 2018 - N°20180086834

The invention relates to chimeric or humanised anti-cd303 antibodies to nucleic acids coding for the heavy and light chains of these antibodies, expression vectors, host cells, transgenic non-human animals or transgenic plants expressing said antibodies, as well as to the uses thereof in the treatment or prevention of blastic plasmacytoid dendritic cell neoplasms (bpdcn) or inflammatory diseases, in particular autoimmune ...
Neoplasm Patent Pack
Download + patent application PDFs
Neoplasm Patent Applications
Download + Neoplasm-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Neoplasm-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Combination of panobinostat and ruxolitinib in the treatment of cancer such as a myeloproliferative neoplasm
March 29, 2018 - N°20180085371

For simultaneous, concurrent, separate or sequential use, especially for use in the treatment of proliferative diseases. The invention also relates to pharmaceutical compositions comprising such a combination and to a method of treating proliferative diseases, in a mammal, particularly a human, with such a combination. The present invention further also relates to a commercial package or product comprising such a ...
Combined composition for preventing or treating cancer comprising a benzophenone thiazole derivatives as a vda ...
National Cancer Center
March 29, 2018 - N°20180085363

The present invention relates to a pharmaceutical combined composition for preventing or treating cancer comprising a compound of formula 1 or a pharmaceutically acceptable salt thereof and topoisomerase inhibitor as active ingredients. The pharmaceutical combined composition of the present invention specifically inhibits cell proliferation and induces apoptosis as to various cancers such as colorectal cancer and ovarian cancer that a vascular ...
Monitoring health and disease status using clonotype profiles
Adaptive Biotechnologies Corp.
March 22, 2018 - N°20180080090

There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer, especially lymphoid neoplasms, such as lymphomas and leukemias. Provided herein are methods for using dna sequencing to identify personalized, or patient-specific biomarkers in patients with lymphoid neoplasms, autoimmune disease and other conditions. Identified biomarkers can be used to ...
Neoplasm Patent Pack
Download + patent application PDFs
Neoplasm Patent Applications
Download + Neoplasm-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Neoplasm-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Combination therapy comprising an inhibitor of jak, cdk, and pim
Novartis Ag
March 15, 2018 - N°20180071296

The present invention relates to a pharmaceutical combination which comprises (a) a jak inhibitor compound, (b) a cdk inhibitor, and (c) a pim kinase inhibitor compound, and optionally, at least one pharmaceutically acceptable carrier for simultaneous, separate or sequential use, in particular for the treatment of a myeloid neoplasm or leukemia; a pharmaceutical composition comprising such a combination; the use ...
1-amino-triazolo(1,5-a)pyridine-substituted urea derivative and uses thereof
Kala Pharmaceuticals, Inc.
March 01, 2018 - N°20180057489

Provided herein is a compound, 1-(4-(3-amino-[1,2,3]triazolo[1,5-a]pyridin-4-yl)phenyl)-3-(3-chlorophenyl)urea, pharmaceutical compositions thereof and crystal forms thereof. Also provided are particles (e. G., nanoparticles) comprising the compound, and pharmaceutical compositions thereof that are mucus penetrating. Also provided herein are methods and kits for using the compound, and pharmaceutical compositions thereof for treating and/...
T cell receptor knock out engineered immune cells, endowed with chimeric antigen receptors binding to ...
Cellectis
February 22, 2018 - N°20180051089

The present invention relates to a tcr ko—or tcr ko and dck ko—engineered immune cells expressing a chimeric antigen receptors (car) specific for cd123 that is a recombinant chimeric protein able to redirect immune cell specificity and reactivity toward cd123-expressing cells, and more particularly in which extracellular ligand binding is a scfv derived from a ...
Urea derivatives and uses thereof
Kala Pharmaceuticals, Inc.
February 08, 2018 - N°20180037573

The present invention provides novel compounds of any one of formulae (i)-(iii), and pharmaceutical compositions thereof. Also provided are particles (e. G., nanoparticles) comprising compounds of formula (i)-(iii) and pharmaceutical compositions thereof that are mucus penetrating. The invention also provides methods and kits for using the inventive compounds, and pharmaceutical compositions thereof, for treating and/or ...
Urea derivatives and uses thereof
Kala Pharmaceuticals, Inc.
February 08, 2018 - N°20180037572

The present invention provides novel compounds of any one of formulae (i)-(iii), and pharmaceutical compositions thereof. Also provided are particles (e. G., nanoparticles) comprising compounds of formula (i)-(iii) and pharmaceutical compositions thereof that are mucus penetrating. The invention also provides methods and kits for using the inventive compounds, and pharmaceutical compositions thereof, for treating and/or ...
Methods of increasing delivery of anti-cancer agents to targets
Oncoquest, Inc.
January 04, 2018 - N°20180002441

The present invention provides compositions and methods for increasing the permeability of a stroma around a neoplasm, and particularly to cancer cells associated with solid tumors. In one embodiment, combining a therapeutic ige antibody with an anti-cancer agent in accordance with the invention increases the delivery of the anticancer agent to the site of, for example, a solid tumor in ...
Rapid quantitative detection of single nucleotide polymorphisms or somatic variants and methods to identify malignant ...
The General Hospital Corporation
December 28, 2017 - N°20170369939

Provided are systems, kits, and methods for the quantitative detection of single nucleotide polymorphisms or variants to identify malignant neoplasms. The methods include use of modified oligonucleotide blockers with peptide nucleic acid backbones that hybridize to and block logarithmic amplification of the wild-type alleles of a target, and incorporation of locked nucleic acids into probes that are complementary to a ...
Neoplasm Patent Pack
Download + patent application PDFs
Neoplasm Patent Applications
Download + Neoplasm-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Neoplasm-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Monitoring health and disease status using clonotype profiles
Adaptive Biotechnologies Corp.
December 07, 2017 - N°20170349954

There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer, especially lymphoid neoplasms, such as lymphomas and leukemias. Provided herein are methods for using dna sequencing to identify personalized, or patient-specific biomarkers in patients with lymphoid neoplasms, autoimmune disease and other conditions. Identified biomarkers can be used to ...
Methods and compositions for single chain variable region enox2 antibodies for cancer detection and diagnosis
Mor-nuco Enterprises, Inc.
November 30, 2017 - N°20170343555

Cancers of different cellular or tissue origins express different enox2 cancer isoforms or combinations of isoforms and shed these proteins into the circulation. Herein are disclosed methods both for cancer detection and diagnosis of particular origin, based on the patterns and molecular weights of the isoforms which allow the identification of the cell type and or tissue of origin of ...
Amino-substituted isothiazoles
Bayer Pharma Aktiengesellschaft
November 23, 2017 - N°20170334899

The present invention relates to amino-substituted isothiazoles of general formula (i): in which a, r1 and r2 are as defined in the claims, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment ...
Inhibitors of cyclin-dependent kinase 7 (cdk7)
November 16, 2017 - N°20170327496

The present invention provides novel compounds of formula (i) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e. G., cancers (e. G., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in ...
Benzimidazol-2-amines as midh1 inhibitors
Bayer Pharma Aktiengesellschaft
November 09, 2017 - N°20170320861

The present invention relates to benzim-idazol-2-amines of general formula (i) in which r1, r2, r3, r4, r5, r6, r7, r8, r9, r10, r11 and r12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for ...
1-cyclohexyl-2-phenylaminobenzimidazoles as midh1 inhibitors for the treatment of tumors
Bayer Pharma Aktiengesellschaft
November 09, 2017 - N°20170319549

The present invention relates to benzimidazol-2-amines of general formula (i) in which r1, r2, r3, r4, r5, r6, r7, r8, r9, r10, r11 and r12 are as defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for ...
Substituted tetracycline compounds
Paratek Pharmaceuticals, Inc.
October 26, 2017 - N°20170305840

The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
Combinations for the treatment of neoplasms using quiescent cell targeting and inhibitors of mitosis
October 19, 2017 - N°20170296542

The present invention provides compositions and methods for the treatment of neoplasms, in particular, by targeting of quiescent cancer cells with therapeutic agents in combination with other treatments effective against certain neoplastic conditions, in particular, anti-cancer treatment with therapeutic agents that are inhibitors of mitosis (a mitotic inhibitor).
Loading