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Monoclonal Antibody

Monoclonal Antibody-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Test object detection method, and immunoassay instrument and monoclonal antibody for same
Denka Seiken Co., Ltd.
June 14, 2018 - N°20180164316

Disclosed is a novel method of detecting a test subject by an immunoassay, in which low sensitivity due to using a monoclonal antibody is improved in spite of using a monoclonal antibody in the immunoassay. The method of detecting a test subject is a method of detecting a test subject having two or more kinds of antigens which enable detection ...
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
Immunomedics, Inc.
June 14, 2018 - N°20180162945

The present invention concerns compositions and methods of use of anti-hla-dr antibodies or fragments thereof. In preferred embodiments, the antibodies are subcutaneously administered to a human patient with a hematologic cancer or autoimmune disease.
Optimizing diagnostics for galactofuranose containing antigens
The Johns Hopkins University
June 07, 2018 - N°20180156797

Disclosed herein are methods of detecting microbial infection in mammalian subjects comprising treatment of a sample and detection of galactofuranose (galf)-containing antigenic components utilizing monoclonal antibodies. The methods disclosed provide for pretreatment of biological samples, such as urine samples, to maximize detection of galf antigens and improvement of sensitivity of galf antigen detection assays.
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Monoclonal Antibody Patent Applications
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  • 139+ full patent PDF documents of Monoclonal Antibody-related inventions.
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Diagnosis and treatment of cancer using anti-itm2a antibody
Chugai Seiyaku Kabushiki Kaisha
June 07, 2018 - N°20180155438

Disclosed is a monoclonal antibody binding to an itm2a protein. This antibody is useful in the diagnosis, prevention, and treatment of cancer such as ewing's sarcoma, t cell leukemia, t cell lymphoma, acute myeloid leukemia, b cell tumor, and multiple myeloma.
Combination therapies with recombinant listeria strains
Advaxis, Inc.
June 07, 2018 - N°20180153974

The disclosure is directed to compositions comprising an oncolytic virus, chimeric antigen receptor t cells (car t cells), a therapeutic or immunomodulating monoclonal antibody, a targeting thymidine kinase inhibitor (tki), or an adoptively transferred cells incorporating engineered t cell receptors, and a live attenuated recombinant listeria strain comprising a fusion protein of a truncated llo, a truncated acta or a ...
Method for quantifying monoclonal antibody
National Cancer Center
May 31, 2018 - N°20180148763

The present invention provides a method for quantifying a monoclonal antibody, the method including: a step of performing selective protease digestion of a monoclonal antibody as a measurement target by bringing a porous body in which the monoclonal antibody is immobilized in pores into contact with fine particles onto which a specific protease is immobilized; and a step of detecting ...
Monoclonal Antibody Patent Pack
Download 139+ patent application PDFs
Monoclonal Antibody Patent Applications
Download 139+ Monoclonal Antibody-related PDFs
For professional research & prior art discovery
inventor
  • 139+ full patent PDF documents of Monoclonal Antibody-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Ca6 antigen-specific cytotoxic conjugate and methods of using the same
Sanofi
May 10, 2018 - N°20180127511

Cytotoxic conjugates comprising a cell binding agent and a cytotoxic agent, therapeutic compositions comprising the conjugate, methods for using the conjugates in the inhibition of cell growth and the treatment of disease, and a kit comprising the cytotoxic conjugate are disclosed are all embodiments of the invention. In particular, the cell binding agent is a monoclonal antibody, and epitope-binding fragments ...
Human monoclonal antibodies fragments inhibiting both the cath-d catalytic activity and its binding to the ...
Institut Regional Du Cancer De Montpellier
May 10, 2018 - N°20180127510

The invention relates to human anti-cath-d neutralizing monoclonal antibodies and uses thereof. More particularly, the invention relates to an isolated human monoclonal antibody or a fragment thereof comprising a heavy chain variable region comprising seq id no: 2 in the h-cdr1 region, seq id no: 3 in the h-cdr2 region and seq id no: 4 in the h-cdr3 region; and a light chain ...
Treating refractory migraine
Teva Pharmaceuticals International Gmbh
May 10, 2018 - N°20180127490

Disclosed herein are methods of treating or reducing incidence of migraine and/or at least one secondary symptom associated with refractory migraine in a subject having refractory migraine comprising administering to the subject a monoclonal antibody that modulates the cgrp pathway. Compositions for use in the disclosed methods are also provided.
Immunoglobulins and uses thereof
Janssen Pharmaceutica Nv
May 10, 2018 - N°20180125998

The present invention relates to a monoclonal antibody platform designed to be coupled to therapeutic peptides to increase the half-life of the therapeutic peptide in a subject. The invention also relates to pharmaceutical compositions and methods for use thereof..
Antibody-coupled cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide y receptors
Janssen Pharmaceutica Nv
May 03, 2018 - N°20180117170

The present invention comprises conjugates comprising a monoclonal antibody conjugated to a cyclic pyy peptide. The invention also relates to pharmaceutical compositions and methods for use thereof.
Quantifying monoclonal antibody therapeutics by lc-ms/ms
Mayo Foundation For Medical Education And Research
April 19, 2018 - N°20180106815

This document relates to methods for quantifying antibody therapeutics using mass spectrometry techniques.. .
Antibody directed against immunoglobulin-binding proteins of s. aureus
Arsanis Biosciences Gmbh
April 19, 2018 - N°20180105584

A monoclonal antibody that counteracts staphylococcus aureus by specifically binding to wild-type immunoglobulin-binding proteins (igbp) of s. Aureus comprising a cross-specific cdr binding site recognizing at least three of the igbp domains selected from the group consisting of protein a (spa) domains and immunoglobulin-binding protein (sbi) domains spa-a, spa-b, spa-c, spa-d, spa-e, sbi-i, and sbi-ii, wherein the antibody has an ...
Monoclonal Antibody Patent Pack
Download 139+ patent application PDFs
Monoclonal Antibody Patent Applications
Download 139+ Monoclonal Antibody-related PDFs
For professional research & prior art discovery
inventor
  • 139+ full patent PDF documents of Monoclonal Antibody-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Monoclonal antibodies to fibroblast growth factor receptor 2
Galaxy Biotech, Llc
April 05, 2018 - N°20180094063

The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and methods of treatment comprising administering such a pharmaceutical composition to a patient.. .
Igf-1r antibody and its use for the diagnosis of cancer
Pierre Fabre Medicament
April 05, 2018 - N°20180094060

The present disclosure relates to a novel antibody, in particular a monoclonal antibody, capable of binding to igf-1r, as well as the amino and nucleic acid sequences coding for said antibody.. .
Lung cancer diagnosis marker, antibody and application thereof
April 05, 2018 - N°20180094042

A human lung cancer marker n3g4, and use of the same as human lung cancer marker is disclosed. Hybridoma cells which produce anti-n3g4 monoclonal antibodies, and the secreted monoclonal antibody lc128, and use of lc128 for the preparation of a diagnostic agent for lung cancer are also disclosed.
Novel monoclonal antibody inhibitors targeting potassium channel kcnk9
The Johns Hopkins University
April 05, 2018 - N°20180092977

The presently disclosed subject matter relates to antibodies, antibody fragments or derivatives thereof, which specifically bind to and/or interact with at least one epitope of the extracellular domain of the mammalian kcnk9 potassium channel, and to nucleic acid molecules encoding the same, as well as to vectors comprising said nucleic acid molecules. The presently disclosed subject matter provides methods ...
Methods for suppressing allergic reactions
Children's Hospital Medical Center
April 05, 2018 - N°20180092929

A method of treating a subject suffering from an allergic disorder is provided, the method including inducing rapid desensitization to an allergen, the rapid desensitization effectuated by: administering to the subject a plurality of equal doses of a first anti-fcεriα monoclonal antibody, wherein the plurality of equal doses are administered over a 6 to 8 hour period ...
Oncolytic adenoviruses coding for bi-specific antibodies and methods and uses related thereto
Tilt Biotherapeutics Oy
March 15, 2018 - N°20180072809

The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to cancer therapies of humans.
Novel anti-netrin-1 antibody
Netris Pharma
March 15, 2018 - N°20180072800

The application discloses a linear or substantially linear epitope on netrin-1 that likely corresponds to the specific binding region of netrin-1 to receptor, in particular of the unc5 class, especially unc5b and unc5a, or alternatively corresponds to a region nearby the specific binding region of netrin-1 to receptor that when bound to an antibody prevents netrin-1/receptor interaction. ...
Method for detecting monoclonal antibody using mass spectrometry
March 01, 2018 - N°20180059074

In the method, a porous body in which a monoclonal antibody is immobilized in pores and nanoparticles on which a protease is immobilized are brought into contact with each other in a liquid to perform selective proteolysis of the monoclonal antibody, and a resulting peptide fragment is detected using liquid chromatography-mass spectrometry (lc-ms), and a peptide having an amino acid ...
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