|| List of recent Molecular-related patents
|Computational methods for analysis and molecular design of antibodies, antibody humanization, and epitope mapping coupled to a user-interactive web browser with embedded three- dimensional rendering|
This disclosure relates in general to the field of antibody modeling and analysis. The disclosed subject matter describes a single online workspace to model and analyze antibody sequences or structures.
|Solid-phase polymerization method for preparing high-molecular-weight aliphatic polyester|
A solid-phase polymerization method of high-molecular-weight aliphatic polyester conducts the solid-phase polymerization of aliphatic polyester prepolymer under a gas stream containing sulfonic acid catalyst. The method features preparing metal free aliphatic polyester with high molecular weight, good color and luster and perfect thermal stability efficiently.
|Process for making low viscosity, fast curing silane terminated polymers|
Methods of producing a composition comprising a crosslinkable silane-terminated polymer having at least one cross-linkable silyl group in each molecule are provided. The method may comprise providing a polymer having at least one unsaturated group and at least one alcohol hydroxyl group in each molecule and having a number average molecular weight between about 100 and about 5,000, adding to the polymer a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule and a hydrosilylation catalyst to thereby carry out a hydrosilylation reaction to form a composition comprising hydrosilylated polymers, wherein the hydrosilylation reaction has a hydrosilylation efficiency greater than 50% as determined by 1h-nmr, capping the hydrosilylated polymers by adding the hydrosilylated polymer to at least one isocyanate at an index of between about 100 and about 250, and reacting the isocyanate capped hydrosilylated polymer with a polyol having a nominal functionality of at least 2 to form the composition comprising a crosslinkable silane-terminated polymer..
|Sponge polymer with controlled long chain branching and broad molecular weight distribution|
A process and the resultant product from the process for continuously making an epdm utilizing ethylene, propylene, and dienes. This process allows for the creation of products with high diene contents and broad molecular weight distributions while utilizing a continuous flow reactor and a known catalyst.
|Process for creating an ethylene elastomer|
A process for continuously making a terpolymer or a tetrapolymer utilizing ethylene, an alpha olefin, and at least one polyene. This process allows for the creation of products with high polyene contents and broad molecular weight distributions while utilizing a continuous flow reactor and a known catalyst.
|Thermoplastic elastomer compositions having biorenewable content|
Thermoplastic elastomer compositions, in particular derived from one or more styrenic block copolymers wherein at least one styrenic block copolymer comprises a controlled distribution copolymer block including a conjugated diene and a mono alkenyl arene, a plurality of biorenewable materials, preferably a softener and one or more synergistic additives such as a polar polymer; a synergistic block copolymer such as a relatively high molecular weight styrenic block copolymer; and/or filler. Numerous desirable articles can be formed from the compositions.
|Thermoplastic elastomer compositions having biorenewable content|
Thermoplastic elastomer compositions, in particular derived from one or more styrenic block copolymers, a plurality of biorenewable materials, preferably a softener and one or more synergistic additives such as a polar polymer; a synergistic block copolymer such as a relatively high molecular weight styrenic block copolymer; and/or filler. In one preferred embodiment, the styrenic block copolymer comprises a controlled distribution copolymer block including a conjugated diene and a mono alkenyl arene.
|Method of diagnosing and treating epstein barr virus-based myalgic encephalomyelitis chronic fatigue syndrome patients|
A method of diagnosing a subset of epstein barr virus, myalgic encephalomyelitis chronic fatigue syndrome (me/cfs) patients through a multi-prong clinical/serological analysis is provided wherein epstein barr virus abortive lytic replication (ebv) is determined as the specific causal agent through the use of serum antibodies to ebv encoded dutpase and serum antibodies to ebv dna polymerase as molecular markers. A method of treating patients diagnosed with epstein barr virus abortive lytic replication (ebv), myalgic encephalomyelitis chronic fatigue syndrome (me/cfs) with specific antiviral nucleosides is also provided, to alleviate the condition..
|Methods and compositions for the diagnosis of ovarian cancer|
A diagnostic reagent or device comprises at least one ligand capable of specifically complexing with, binding to, or quantitatively detecting or identifying the biomarker chloride intracellular channel protein 4 (clic4) or an isoform, pro-form, modified molecular form including posttranslational modification, or unique peptide fragment or nucleic acid fragment thereof. An alternative diagnostic reagent or device comprises ligand or ligands capable of specifically complexing with, binding to, or quantitatively detecting or identifying multiple tropomyosin biomarkers.
|Soybean event dp-305423-1 and compositions and methods for the identification and/or detection thereor|
Compositions and methods related to transgenic high oleic acid/als inhibitor-tolerant soybean plants are provided. Specifically, the present invention provides soybean plants having a dp-305423-1 event which imparts a high oleic acid phenotype and tolerance to at least one als-inhibiting herbicide.
|Devices and methods for cell lysis and sample preparation through centrifugation|
Methods and devices for molecular analysis are disclosed, based on centrifugation. A centrifuge device comprises strips of centrifuge tubes and elements to create a magnetic field.
|Panel for the detection and differentiation of renal cortical neoplasms|
The present invention provides a novel, highly sensitive and specific probe panel which detects the type of renal cortical neoplasm present in a biopsy sample. As such, the invention permits diagnosis of the predominant subtypes of renal cortical neoplasms without the use of invasive methods.
|Brassica gat event and compositions and methods for the identification and/or detection thereof|
Compositions and methods related to transgenic glyphosate tolerant brassica plants are provided. Specifically, the present invention provides brassica plants having a dp-073496-4 event which imparts tolerance to glyphosate.
|Fuel cell comprising a proton-exchange membrane, having an increased service life|
A fuel cell having a proton-exchange membrane, an anode, and a cathode. The anode and cathode are fixed on opposing sides of the proton-exchange membrane.
|Processing method for fiber material used to form biocomposite component|
The present invention is directed to plant fiber-reinforced biocomposite thermoplastic and/or resin compositions and a method for reinforcing thermoplastic resins. The present invention provides a use for the cellulose portion of a plant material, which is the portion left over after processing the selected plant materials to separate the cellulose in a mechanical process that does not damage the internal molecular structure of the cellulose fraction, enabling the cellulose fraction to chemically bond with the thermoplastic resin to enhance the reinforcement of the resin or thermoplastic biocomposite composition..
|D1363 bt radiation curable primary coatings on optical fiber|
Radiation curable coatings for use as a primary coating for optical fibers, optical fibers coated with said coatings and methods for the preparation of coated optical fibers. The radiation curable coating comprises at least one (meth)acrylate functional oligomer and a photoinitiator, wherein the urethane-(meth)acrylate oligomer ca/cr comprises (meth)acrylate groups, at least one polyol backbone and urethane groups, wherein about 15% or more of the urethane groups are derived from one or both of 2,4- and 2,6-toluene diisocyanate, wherein at least 15% of the urethane groups are derived from a cyclic or branched aliphatic isocyanate, and wherein said (meth)acrylate functional oligomer has a number average molecular weight of from at least about 4000 g/mol to less than or equal to about 15,000 g/mol; and wherein a cured film of the radiation curable primary coating composition has a modulus of less than or equal to about 1.2 mpa..
|Electroconductive polymer, electroconductive polymer aqueous solution, electroconductive polymer film, solid electrolytic capacitor and method for producing the same|
An electroconductive polymer having high electroconductivity, an electroconductive polymer aqueous solution, and an electroconductive polymer film are provided. Further, a solid electrolytic capacitor having a reduced esr and a method for producing the same are provided.
|Inkjet ink with non-swellable latex particles|
An inkjet ink includes a non-polar carrier, a colorant dispersed in the non-polar carrier, a dispersant, and non-swellable latex particles of a cross-linked polymer dispersed in the non-polar carrier. The colorant is chosen from a pigment, a dye, or a combination of a pigment and a dye.
|Xcl power producer|
The xcl power producer works by moving molecules to said bodies and continues to move at uniform velocities acted upon vacuum pressures by force, which creates an acceleration of energy production. Produces 45,000 volts @ 300 amps every 4 minutes for a 14 year cycle, continually, as a main power source or back-up system.
|Process for preparing crosslinked polymer-carbon sorbent|
A polymer-carbon sorbent for removing at least one of carbon dioxide, heavy metals or toxic materials from a flue gas from a combustion process, such as coal-fired power plants, is described. The sorbent comprises a carbonaceous sorbent material and a cured amine-containing polymer, and sulfur.
|Mass spectrometer, system comprising the same, and methods for determining isotopic anatomy of compounds|
A first mass spectrometer includes a first introduction device configured to select between a reference material and a first portion of an analyte and introduce the selected one of the reference material or the first portion of the analyte to an ion source, the first mass spectrometer being configured to provide third molecular analyte ions to a detector at a first mass resolution of about 30,000 or greater. A system includes the first mass spectrometer and a second mass spectrometer.
|Methods for production of proteins|
The current invention provides methods for producing a polypeptide as inclusion bodies in bacterial host cells. The present methods are carried out by forming a gene construct comprising the genetic sequence encoding a polypeptide operatively linked to that of an inclusion partner protein, such that host cells comprising the gene construct produce the polypeptide as intracellular inclusion bodies thereby facilitating rapid isolation and purification of recombinant proteins.
A molecular fan for dissipating heat, the fan having a chemically functionalized molecular fan thin film coating affixed to a surface in need of heat dissipation. A nanocoating for dissipating heat, the coating having a thin film coating affixed to a surface in need of heat dissipation.
|Method and apparatus for fabricating an ultra-high molecular weight polymer structure|
A polymer laminate is fabricated by laying down layers of an ultra-high molecular weight polymer material on top of each other, and fusing the layers to each other by cross-linking molecular chains of adjoining layers.. .
|Biomass conversion systems and methods for use thereof|
Digestion of cellulosic biomass solids to form a hydrolysate may be accompanied by decomposition if the soluble carbohydrates produced from the biomass under hydrothermal digestion conditions are not transformed into a more stable reaction product. Biomass conversion systems may be configured to address this issue and others.
|Contact lens products|
The present invention relates to improved contact lens products which not only have initial insertion comfort but also are comfortable to wear for more than about 6 hours. The invention is achieved by packaging and storing a hydrogel lens with two or more leachable polymeric lubricants incorporated therein in a relatively viscous packaging solution including a relatively low molecular weight polyethylene glycol (peg) and a viscosity-enhancing hydrophilic polymer.
|Microsomal omega6 oleate desaturases|
The present invention relates to the field of plant molecular biology, more particularly jatropha microsomal co6 oleate desaturases. The present invention also relates to jatropha plants or plants of other oil crops having seeds with altered ratios of monosaturated and polyunsaturated fats.
|Plants having enhanced yield-related traits and a method for making the same|
The present invention relates generally to the field of molecular biology and concerns a method for enhancing various yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding a tcp1 or a tcp2 transcription factor, an epsin-like polypeptide, a trna delta(2)-isopentenylpyrophosphate transferase (ippt) polypeptide, or a short-root (shr) polypeptide. The present invention also concerns plants having modulated expression of a nucleic acid encoding a tcp1 or tcp2 polypeptide, an epsin-like polypeptide, a trna delta(2)-isopentenylpyrophosphate transferase (ippt) polypeptide, or a short-root (shr) polypeptide, which plants have enhanced yield-related traits relative to corresponding wild type plants or other control plants.
|Method of identifying airborne molecular contamination source|
The present disclosure provides a method of identifying an airborne molecular contamination (amc) leaking source in a fab. The method includes distributing a sensor in the fab, executing a forward computational fluid dynamics (cfd) simulation of an air flow in the fab, setting an inversed modeling of the forward cfd simulation of the air flow in the fab, building up a database of a spatial response probability distribution matrix of the sensor using an amc measurement data in the fab, and identifying the amc leaking source using the database of the spatial response probability distribution matrix of the sensor..
|Fluidic channel coated with metal catalysts and devices and methods relating thereto|
The invention provides a method for coating fluidic channels, particularly millifluidic channels, with a catalyst coating having controlled dimensions and morphology, and methods for preparing such channels, and devices that can be used in combination with the channels. The invention further provides portable, hand-held millifluidic devices applicable for a wide variety of uses including molecular reduction reactions, in situ material characterization, in situ reaction catalysis characterization, in situ reaction mechanism characterization, nanomaterial synthesis, nanostructured metal and metal oxide growth and coating of channels, continuous flow cell culturing, enzymatic catalysis, biomolecular catalysis, combinatorial chemistry, reactions involving homogeneous catalysts bound to channel walls, peptide synthesis, nucleic acid synthesis, synthesis of pharmaceutical intermediates, biofunctionalization of nanomaterials or a combination thereof..
|Phosphorus-silicon synergistic flame retardants and the prepartion method and use thereof|
The present invention discloses a phosphorus-silicon synergistic flame retardant and the preparation method and use thereof. The phosphorus-silicon synergistic flame retardant provided by the present invention has a structural general formula shown as formula i.
|Fluorocarbon anti-shrinkage leveling agent for coating and ink|
A fluorocarbon leveling agent (fluoride-containing surfactant) for coating and ink has the surface tension of the leveling agent of 21-24 dynes, the number-average molecular weight of 1500-4500, the weight-average molecular weight of 3000-15000, and the polydispersity of 1.5-2.8. The present invention can reduce the surface tension of the coating system and has strong anti-shrinkage capability and excellent long wave leveling..
|Polyolefin and preparation method thereof|
A polyolefin has 1) a density in the range of 0.93 to 0.97 g/cm3, 2) a bocd (broad orthogonal co-monomer distribution) index defined by a given equation in the range of 1 to 5, and 3) a molecular weight distribution (weight average molecular weight/number average molecular weight) in the range of 4 to 10. A supported hybrid metallocene catalyst comprises a first metallocene compound represented by a first given formulae, a second metallocene compound represented by one of three given formulae, and a support..
|Method for producing siloxane oligomers|
[solving means] an embodiment of the present invention is a method for producing siloxane oligomers which includes using a 2-hydroxycarboxylic acid compound represented by a predetermined formula as a catalyst and subjecting an alkoxysilane to hydrolysis and condensation. According to the production method of the present invention, it is possible to synthesize siloxane oligomers with a low content of siloxanes having cyclic structures and a high molecular weight..
The present invention provides a curable composition useful as a contact adhesive which has a high rate of initial tack development, high tack strength, and long retention time of the developed tack. The curable composition includes an organic polymer (q) containing a reactive silyl group, and a linear organic polymer (p) having a number average molecular weight larger than that of the polymer (q) and having a reactive silyl group containing three hydrolyzable groups at only one terminal.
|Thermoplastic elastomer compounds exhibiting superior compression set properties|
A blend of polyisobutylene-based thermoplastic vulcanizate, styrene-ethylene-ethylene-propylene-styrene, low molecular weight liquid polybutene, polyolefin, polyphenylene ether, and, optionally, filler is disclosed which has good processability, lower compression set, and more effective barrier properties for oxygen than the same blend without the styrene-ethylene-ethylene-propylene-styrene and the polyphenylene ether. The blend is superior in oxygen transmission rate properties than a conventional styrenic block copolymer containing thermoplastic elastomer..
|Molecular containers and methods of making and using same|
Acyclic cb[n]-type compounds, methods of making such compounds, and uses of the compounds. For example, these compounds can be used as nanocontainers to solubilize pharmaceutical agents.
|Method of utilizing azelaic acid esters to modulate communications mediated by biological molecules|
The treatment of disease in organisms using macromolecular interaction modulators and membrane active immunomodulators, particularly selected azelaic acid esters, individually and in combinations, to modulate communications between biological molecules.. .
|Use of dextran sulfate|
A method of inhibiting instant blood-mediated inflammatory reaction (ibmir) in a patient, comprises administering a therapeutically effective amount of dextran sulfate, or a pharmaceutically acceptable salt thereof. A method of inhibiting morphological disruption of a transplanted cell transplant in a patient comprises administering a therapeutically effective amount of dextran sulfate, or a pharmaceutically acceptable salt thereof, to a patient.
|Hyaluronic acid compositions stabilised against the degrading effect of heat or enzymes|
The invention relates to the use of an additive to stabilise hyaluronic acid formulated in an aqueous composition against the degrading effect of heat or of enzymes such as hyaluronidase, characterised in that said additive comprises one or more polysaccharides having a molecular weight equal to or greater than 20,000 daltons and solubility in water at least equal to or greater than 1 g/l, the total concentration of said polysaccharide(s) and hyaluronic acid in the composition giving it a viscosity of at least 500 cp, which is particularly suitable for intra-articular, intradermal or intraocular administration to humans or animals.. .
|Method of manufacturing an organic semiconductor thin film|
A method of manufacturing an organic semiconductor thin film includes coating an organic semiconductor solution on a substrate, and shearing the organic semiconductor solution in a direction that results in a shearing stress being applied to the organic semiconductor solution to form the organic semiconductor thin film, wherein a speed of the shearing is controlled such that an intermolecular distance of the organic semiconductor solution is adjusted.. .
|Cell differentiation inducer and differentiation inducing method|
The objective of the present invention is to provide a cell differentiation inducer which is a low-molecular compound, which can be chemically synthesized easily and which can efficiently induce a differentiation of an undifferentiated cell into a nervous system cell with high selectivity. In addition, the objective of the present invention is to provide use of a specific catechol derivative for efficiently inducing a differentiation of an undifferentiated cell into a nervous system cell with high selectivity, and a method for efficiently inducing a differentiation of an undifferentiated cell into a nervous system cell with high selectivity using a specific catechol derivative.
|Tannase, gene encoding same, and process for producing same|
Disclosed is a thermostable tannase derived from a microorganism. Specifically disclosed is a thermostable tannase derived from aspergillus awamori or aspergillus niger.
|Protein removal agent|
The present invention provides compositions, methods and kits for the removal of proteins from complex reaction mixtures useful in majority workflows of molecular biology research experiments. More specifically, such compositions, methods and kits are useful in such processes as purification of nucleic acids from biological samples or after their treatment with specific enzymes, when residual enzyme activity in reaction mixture is not compatible with downstream applications..
|Fluorescent probes for monitoring voltage by photo-induced electron transfer|
Compounds and methods for determining transmembrane potential, monitoring changes in transmembrane potential, and/or drug screening are provided. In one aspect, compounds of the invention have a structure according to the formula: e-m-a, wherein a is a fluorophore, selected from xanthenes, eoumarins, cyanines, bimanes, and difluoroboradizaindacenes, charged at physiological ph; m is a molecular wire; and e is a hydrophobic moiety, wherein a and e are capable of being involved in a photo-induced, intramolecular electron transfer that quenches the fluorescence of a in response to a voltage condition.
|Method and apparatus for generating thermal melting curves in a microfluidic device|
The present invention provides novel methods and devices that employ microfluidic technology to generate molecular melt curves. In particular, the devices and methods in accordance with the invention are useful in providing for the analysis of pcr amplification products..
|Resist pattern formation method and resist composition|
A resist pattern formation method including formation of a resist film, exposure, development, and subsequent rinsing using a resist composition containing a high-molecular compound having a constituent unit represented by the formula (a0-1), a constituent unit containing an acid decomposable group whose polarity increases by the action of an acid, and a constituent unit containing a group represented by the formula (a2-r-1). R represents a hydrogen atom, an alkyl group, or a halogenated alkyl group; ra01 represents a lactone-containing polycyclic group, an —so2-containing polycyclic group, or a cyano group-containing polycyclic group; ra′21 represents a hydrogen atom, an alkyl group, an alkoxy group, a halogen atom, a halogenated alkyl group, a hydroxyl group, —coor″, —oc(═o)r″, a hydroxyalkyl group, or a cyano group; r″ represents a hydrogen atom or an alkyl group; and n′ represents an integer of from 0 to 2..
|Nonaqueous electrolyte secondary battery|
To realize high capacity of batteries, an object of the invention is to provide nonaqueous electrolyte secondary batteries which are unlikely to become swollen when charged to a high voltage and allowed to stand in a high temperature atmosphere. The nonaqueous electrolyte secondary battery includes a positive electrode including a positive electrode active material, a negative electrode including a negative electrode active material, a nonaqueous electrolyte, and a separator disposed between the positive electrode and the negative electrode.
|Irradiation assisted nucleation of quantum confinements by atomic layer deposition|
A method of fabricating quantum confinements is provided. The method includes depositing, using a deposition apparatus, a material layer on a substrate, where the depositing includes irradiating the layer, before a cycle, during a cycle, and/or after a cycle of the deposition to alter nucleation of quantum confinements in the material layer to control a size and/or a shape of the quantum confinements.
|Repellent surfacing solutions and mixtures for treatment of surfaces|
The invention describes methodological approach and process for preparation of variable compositions of water-(hydrophobic), oil- and dust-repellent multi-component mixtures containing non-cyclic silanes, siloxanes, hydrocarbons, silane-carbons), cyclic molecular compounds (cyclic-silanes, hydrocarbons, silane-carbons and their derivatives) and other hydrophobic molecular components (as separate molecular substances or as molecular substitutes within the silanes and/or the cyclic compound molecules). Such methodological approach offers best flexibility for repellant mixtures preparation in achieving highly repellant properties, durability and long-lasting (permanent) bonding for specific surface applications and for preparation of other subsequent types of repellant surfacing solutions such as paints or sealing agents, textiles and else..
The present invention relates generally to the fields of molecular biology and growth factor regulation. More specifically, the invention relates to therapies for the treatment of pathological conditions, such as cancer..
|Molecular sieves and related methods and structure directing agents|
Method for preparing molecular sieves and molecular sieves obtained thereby are described. The method includes preparing a reaction mixture, comprising a structure directing agent, at least one source of at least one oxide of a tetravalent element, optionally, one or more sources of one or more oxides selected from the group consisting of oxides of trivalent elements, pentavalent elements, and mixtures thereof, optionally, at least one source of an element selected from groups 1 and 2 of the periodic table; and optionally, hydroxide ions or fluoride ions, and maintaining the reaction mixture under conditions sufficient to form crystals of the molecular sieve.
|Chitosan-based hemostatic textile|
A microfibrillar high molecular weight chitosan-based textile can be used as a hemostat. The chitosan has been treated in a nitrogen field by applying energy to ionize nitrogen in and around the chitosan textile.
|Preparation of nanoparticle materials|
A method of producing nanoparticles comprises effecting conversion of a nanoparticle precursor composition to the material of the nanoparticles. The precursor composition comprises a first precursor species containing a first ion to be incorporated into the growing nanoparticles and a separate second precursor species containing a second ion to be incorporated into the growing nanoparticles.
|Transition-metal free reductive cleavage of aromatic c-o, c-n, and c-s bonds by activated silanes|
The present invention describes chemical systems and methods for reducing c—o, c—n, and c—s bonds, said system comprising a mixture of (a) at least one organosilane and (b) at least one strong base, said system being substantially free of a transition-metal compound, and said system optionally comprising at least one molecular hydrogen donor compound, molecular hydrogen, or both.. .
|Ink deposition processes for thin film cigs absorbers|
Efficient processes for making thin film cigs photovoltaic light absorber materials on a substrate. The processes involve depositing cigs polymeric precursor inks in combination with depositing indium gallium selenide molecular precursor inks onto a substrate..
|Compositions and methods for enhancing the structure of hair fibers|
Disclosed are compositions and methods that are able to increase the amount of molecular structure within the cortex of hair fibers. As result, hair fiber diameter, cross sectional area, elasticity and stiffness are all increased.
|Molecular genetic diagnostic system|
A computer-implemented bioinformatics program annotates human genetic variants by integrating multiple sources of information. The program rapidly filters variants that are unlikely to play a role in the etiology of particular diseases.
|Intra-operative molecular imaging|
A system for detecting tumor margins includes a topical protease-specific, fluorescence imaging probe that is activatable by enzymatic activation to produce a visually differentiated signal upon topical application to a targeted cancer cell that secretes an enzyme that activates the protease-specific, fluorescence imaging probe, means for topically administering the imaging probe to the cancer cell; and an imaging device to detect activation of the imaging probe administered to the cancer cell.. .
|Biomass conversion systems having a single-vessel hydrothermal digestion unit/catalytic reduction reactor unit for integrated stabilization of a hydrolysate and methods for use thereof|
Digestion of cellulosic biomass solids may be conducted in a pressure vessel that contains both a hydrothermal digestion unit and a catalytic reduction reactor unit. Biomass conversion systems incorporating such a feature may comprise: a pressure vessel that comprises a first section comprising a hydrothermal digestion unit and a second section comprising a first catalytic reduction reactor unit that contains a first catalyst capable of activating molecular hydrogen; wherein the hydrothermal digestion unit and the first catalytic reduction reactor unit are in fluid communication with one another; a biomass feed mechanism that is operatively connected to the pressure vessel, the biomass feed mechanism being capable of introducing cellulosic biomass solids to the pressure vessel and also capable of withdrawing a reaction product from the first catalytic reduction reactor unit; and a hydrogen feed line that is operatively connected to the first catalytic reduction reactor unit..
|Process of epoxidising cyclohexane|
A process of oxidizing cyclohexane, comprising feeding cyclohexane, an aqueous hydrogen peroxide solution and optionally an organic solvent into a reaction zone through a feed inlet thereof under the oxidation reaction conditions for contact, and providing all or most of the oxidation product at the reaction zone bottom, wherein a part or all of the packing in the reaction zone is a titanium silicate molecular sieve-containing catalyst. The process of oxidizing cyclohexane according to the present invention carries out the oxidation in the reaction zone, which, firstly, utilizes the latent heat from reaction sufficiently so as to achieve energy-saving; secondly, increases the yield of target product and the availability of oxidizer; and thirdly, allows the separation of the oxidation product from the raw material cyclohexane as the reaction proceeds, such that the cost for subsequent separations can be saved..
|Method for producing peptide|
(1) removing n-terminal fmoc group of n-fmoc c-protected amino acid or n-fmoc c-protected peptide wherein a c-terminal carboxy group is protected by an anchor group derived from an anchor soluble in halogenated solvents or ether solvents, insoluble in polar solvents and having a molecular weight of not less than 300, with a non-nucleophilic organic base in a halogenated solvent or ether solvent to give a c-protected amino acid or c-protected peptide, neutralizing with an acid, adding n-fmoc amino acid or n-fmoc peptide, a condensing agent and a condensation accelerator to the reaction solution after neutralization, and condensing the n-terminal of the c-protected amino acid or c-protected peptide with n-fmoc amino acid or n-fmoc peptide to give an n-fmoc c-protected peptide.. .
|Supramolecular initiator for latent cationic epoxy polymerization|
A mixture may include at least one polymerizable species and at least one thermoresponsive supramolecular initiator complex involving a host-guest interaction. Processes for making resins may include mixing at least one polymerizable species with at least one thermoresponsive supramolecular initiator complex involving a host-guest interaction; subjecting the mixture to a temperature above about 30° c.
|Metallocene and half sandwich dual catalyst systems for producing broad molecular weight distribution polymers|
Disclosed herein are polymerization processes for the production of olefin polymers. These polymerization processes can use a dual catalyst system containing a zirconium or hafnium based metallocene compound and a titanium based half-metallocene compound containing an indenyl group..
|Methods for controlling dual catalyst olefin polymerizations|
Methods for controlling the weight ratio of a higher molecular weight component to a lower molecular weight component of an olefin polymer are disclosed. This weight ratio can be increased as polymerization reaction temperature and/or catalyst system residence time are increased..
|Method for polymerisation of (meth)acrylic acid in solution, polymer solutions obtained and their uses|
The present invention relates to a new solvent-free preparation method of a (meth)acrylic acid polymer in solution, where said polymer has a molecular weight less than 8,000 g/mol and a polydispersity ip index between 2 and 3 by radical polymerisation, the polymers obtained by this means, and their applications in industry.. .
|Aqueous polyurethane resin dispersion and coating composition comprising the same|
The present invention is to provide an aqueous polyurethane resin dispersion in which a polyurethane resin s dispersed in an aqueous medium, wherein the polyurethane resin is obtained by reacting (a) a polyurethane prepolymer which is obtained by reacting (a) a polyisocyanate compound, (b) a polyol compound containing a polycarbonate polyol having a number average molecular weight of 800 to 3500, and (c) an acidic group-containing polyol compound, and (b) a chain extender, being dispersed in an aqueous medium, (b) the chain extender contains a polyamine compound having three or more in total of an amino group(s) and/or an imino group(s) per molecule, and the polyurethane resin has, each based on a solid content, a content of urethane bonds of 5 to 10% by weight, a content of urea bonds of 2 to 7% by weight, a content of carbonate bonds of 15 to 40% by weight, has neither ether bond nor ester bond, has a density of cross-linking points of 1.0×10−4 to 1.0×10−3 mol/g, an acid value of 12 to 20 mg koh/g, and a weight average molecular weight of 100,000 or more.. .
|Biobased modifiers for polyvinylchloride blends|
Compositions of polymer blends of polyvinylchloride (pvc), a low molecular weight plasticizer and polyhydroxyalkanoate (pha) are described. In certain embodiments, the pha is a poly-3-hydroxybutyrate-co-4-hydroxybutyrate copolymer having a weight percent 4-hydroxybutyrate of 30-45%.
|Thermoset/supramolecular hybrid composites and resins that can be hot-formed and recycled|
Thermoset/supramolecular hybrid composites and resins, resulting from bringing at least one thermosetting resin precursor, this thermosetting resin precursor comprising hydroxyl functions and/or epoxy groups, and optionally ester functions, into contact with at least one hardener chosen from carboxylic acids and acid anhydrides, and with at least one compound comprising, on the one hand, at least one associative group, and on the other hand at least one function enabling the grafting thereof to the thermosetting resin precursor, to the hardener or to the product resulting from the reaction of the thermosetting resin precursor and the hardener, in the presence of at least one transesterification catalyst. Process for manufacturing these materials, process for transforming and process for recycling these materials.
|Differentially expressed microrna molecules for the treatment and diagnosis of cancer|
A significant challenge in cancer research field is to define molecular features that distinguish cancer stem cells from normal stem cells. In this study, microrna (mirna) expression profiles in human glioblastoma stem cells were compared to that of normal neural stem cells using combined microarray and deep sequencing analyses.
|Extended risk assessment panel for individualized treatment of cardiovascular disease, and methods related thereto|
Disclosed is a personalized diagnostic and treatment solution for cardiovascular disease. The invention comprises an extended cvd risk assessment panel, combining tests for traditional and new important risk markers, and methods for devising a personalized treatment plan for a patient via the use of a cvd diagnosis and treatment protocol algorithm.