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|| List of recent Minox-related patents
|Finasteride and minoxidil polymeric nonoparticle, its process of preparation, aqueous suspension containing the same, pharmaceutical composition, and its use|
The present invention relates to a pharmaceutical composition for topical application for the treatment of alopecia, said composition comprising polymeric nanoparticles, preferably nanocapsules containing two active ingredients, finasteride and minoxidil, additives and a pharmaceutically acceptable carrier. The invention further includes a process for the preparation of polymeric nanoparticles, preferably nanocapsules of finasteride and minoxidil, a composition suitable for topical application for the treatment of alopecia, as well as the use of said nanocapsules for the preparation of a pharmaceutical composition..
Universidade Federal Do Ria Grande Do Sul -ufrgs
|Composition for agent for external use|
Upon attempting to design a pharmaceutical preparation by mixing minoxidil with a general thickening agent during a process for considering a minoxidil-containing composition for an agent for external use in which dripping is inhibited, it was discovered that the pharmaceutical preparation would have sediments or would cloud and that a sufficient viscosity of the pharmaceutical preparation could not be obtained. The minoxidil-containing composition for an agent for external use of the present invention is characterized by containing minoxidil (a), a hydroxypropyl cellulose and hypromellose (b), ethanol (c), and water (d).
Taisho Pharmaceutical Co., Ltd
|Compositions and methods for treatment of hair loss|
The present invention is directed to compositions and methods suitable for the treatment of alopecia by topical application include minoxidil sulfate, finasteride, and 17α-estradiol. The combination is characterized by low alcohol content to minimize skin irritation and may be enhanced with the addition of vitamins, minerals, and peptides.
|Method and delivery of a measured dosage of a non-aerosol, non-spray foam composition of minoxidil|
A non-pressurized container that contains one or more of: a foamable composition of minoxidil, or a pharmaceutically acceptable salt thereof, and a dihydrotestosterone blocker in a formulation with a precise density and viscosity to yield a foam with a temperature sensitivity and shear strength designed for inverted application and immediate targeted release at body temperature under a minimal hand applied pressure to the scalp.. .
|Hair growth and/or regrowth compositions|
The present disclosure relates to compositions containing certain pyrimidine compounds such as minoxidil and/or certain pyrimidine sulfate (inner salt) compounds such as minoxidil sulfate and especially compositions containing pyrimidine compounds in combination with an admixtures comprising at least one antioxidant, at least one organic acid and a select fatty acid mixture. The present disclosure also relates to use of the compositions to grow and/or regrow hair and/or prevent hair loss in mammals and particularly in humans..
|Method for manufacturing a small particle diameter product of solid polymethylaluminoxane composition|
A solid polymethylaluminoxane composition is provided having uniform particle diameter in the form of fine particles of less than 5 μm employed to polymerize olefins with high polymerization activity without silica. A method for manufacturing thereof, a polymerization catalyst, and a method for manufacturing a polyolefin are also provided.
Tosoh Finechem Corporation
|Systems and methods for predicting response to minoxidil for the treatment of androgenetic alopecia|
Methods, processes, systems, and apparatuses are disclosed for predicting minoxidil response in the treatment of androgenetic alopecia based on colorimetric assay for sulfotransferase activity. In particular, sult1a1 activity may be used as an indicator of minoxidil response.
|Topical application of dihydrotestosterone for promoting hair growth containing formulations|
The present invention relates to the composition and method of use for the topical application of the potent androgen hormone dihydrotestosterone (dht), used alone or in fixed combination with other hair growth medications; including other androgens, bimatoprost, other prostamides, prostaglandins, minoxidil or apocrine hair growth factors to promote and enhance hair growth of terminal mustache hair, beard hair, also chest hair, and other male androgen sensitive or dependent hair growth in humans or animals.. .
|Composition for topical application for preventing hair loss and stimulating hair growth|
The present invention relates to a composition for topical application for preventing hair loss and stimulating hair growth having a 5α-reductase suppressant and minoxidil. The composition for topical application for preventing hair loss and stimulating hair growth according to the present invention provides equal or superior hair loss prevention and hair growth stimulation effects while using a much smaller dosage than conventional compositions which use oral 5α-reductase inhibitors and minoxidil alone or together..
|Restoration of hair|
A nonirritant composition which is useful in restoring hair and which comprises a normally solid, water-insoluble hair restorer, for example, minoxidil, a normally solid hsieh dermal penetration-facilitator for the hair restorer, for example, pentadecalactone, and a solvent or co-solvent in which the hair restorer and the facilitator are solubilized and which does not impart to the composition irritant properties, and wherein, upon application to the surface of the skin of a recipient, the hair restorer penetrates the dermal layer of the skin and with minimal systemic delivery of the hair restorer into the blood stream of the recipient.. .
Methods of making cocrystals
Disclosed are processes for preparing cocrystals, including processes for scaling up of cocrystal formation, as well as scalable processes for preparing cocrystals. Also disclosed are processes for scaled-up preparation of pterostilbene, progesterone, p-coumaric, and minoxidil cocrystals.
Solid support-polymethylaluminoxane complex, producing same, olefin polymerization catalyst, and producing polyolefin
Disclosed is a solid support-polymethylaluminoxane complex exhibiting a higher polymerization activity than a conventional substance and being homogeneous. Also disclosed is a method for producing an olefin-based polymer having a favorable quality using the complex and a transition metal compound.
Catalyst composition for oligomerization of ethylene and processes of oligomerization
The present invention provides a catalyst composition for the ethylene oligomerization, which comprises 2-imino-1,10-phenanthroline coordinated iron (ii), cobalt (ii) or nickel (ii) chloride as main catalyst and triethylaluminum as cocatalyst. The present invention also provides a process for oligomerization of ethylene is provided, wherein a catalyst composition comprising 2-imino-1,10-phenanthroline coordinated iron (ii), cobalt (ii) or nickel (ii) chloride as main catalyst and triethylaluminum as cocatalyst is used, and the molar ratio of aluminum in the cocatalyst to central metal in the main catalyst ranges from 30 to less than 200.
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