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Metered Dose Inhaler

Metered Dose Inhaler-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Dose indicator for a metered dose inhaler
3m Innovative Properties Company
June 22, 2017 - N°20170173280

The present disclosure relates to a dose indicator comprising, a chassis comprising a 42 chassis frame and a displacement portion, an indexable first display unit, mountable on the chassis, the first display unit being indexable about a first display axis, the indexable first display unit comprising a plurality of indexing teeth, a first display non-return arm, and a drive pawl connected ...
Particulate materials
Nektar Therapeutics
June 22, 2017 - N°20170173006

Embodiments of the invention relate to particles of active substances, methods for preparing the particles, formulations containing the particles, and metered dose inhalers containing such particles or formulations. In one embodiment, a composition of an aerosol formulation is provided and contains a particulate active substance of non-micronized, solid particles having a mass median aerodynamic diameter of less than 10 μ...
Compositions comprising salbutamol sulphate
Mexichem Amanco Holding S.a. De C.v.
June 15, 2017 - N°20170165367

A pharmaceutical composition is described that is suitable for delivery from a pressurised container. The composition is free of polar excipients and comprises: (a) a propellant component that consists essentially of 1,1-difluoroethane (r-152a); (b) a surfactant component that comprises oleic acid; and (c) a drug component that consists of salbutamol sulphate. The pharmaceutical composition can be delivered using a ...
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Methods, devices and systems for pulmonary delivery of active agents
Syqe Medical Ltd.
June 08, 2017 - N°20170157343

Provided herein is a method of pulmonary delivering to a subject at least one pharmacologically active agent being in a plant material, which is effected by pulmonary delivering the agent to the subject using a metered dose inhaler device that is configured to vaporize at least one pre-determined vaporized amount of the agent upon controllably heating the plant material, wherein ...
Methods, devices and systems for pulmonary delivery of active agents
Syqe Medical Ltd.
May 11, 2017 - N°20170127727

Provided herein is a system that includes a metered dose inhaler device for pulmonary delivering to a subject at least one pre-determined vaporized amount of at least one pharmacologically active agent being in a plant material, wherein vaporization is effected by controllably heating the plant material so as to vaporize a pre-determined vaporized amount of the agent; the system further ...
Compositions for pulmonary delivery of long-acting muscarinic antagonists and associated methods and systems
Pearl Therapeutics, Inc.
April 27, 2017 - N°20170112759

Compositions, methods and systems are provided for pulmonary delivery of long-acting muscarinic antagonists and long-acting β2 adrenergic receptor agonists via a metered dose inhaler. In particular embodiments, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
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Metered-dose inhaler counter with switch and metered-dose inhaler including such a counter
Presspart Gmbh & Co. Kg
March 30, 2017 - N°20170087312

A dose counter includes a triggering unit having at least a first and a second trigger member thereon. The triggering unit is configured interact with the canister of a metered-dose inhaler when the canister moves in a longitudinal direction from a rest position to an activation position. A circuit assembly includes a substrate with at least a first and a ...
Combination therapy for copd
Chiesi Farmaceutici S.p.a.
March 23, 2017 - N°20170079949

Aerosol formulations comprising glycopyrronium chloride in combination with formoterol may be administered by means of a pressurized metered dose inhaler (pmdi) for the prevention or treatment of chronic obstructive pulmonary disease. The formulation further comprises a hfa propellant, a co-solvent, and an amount of inorganic acid sufficient to stabilize both the glycopyrronium chloride and the formoterol components. Optionally, the formulation ...
Compositions for respiratory delivery of active agents and associated methods and systems
Pearl Therapeutics, Inc.
March 16, 2017 - N°20170071850

Compositions, methods and systems are provided for pulmonary or nasal delivery of active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
Pharmaceutical solution formulations for pressurised metered dose inhalers
Chiesi Farmaceutici S.p.a.
March 09, 2017 - N°20170065518

The invention relates to the prevention and/or treatment of a severe broncho-pulmonary disease by administering a solution formulation from a pressurized metered dose inhaler capable of providing therapeutical doses of two or more active drug substances to the lung, wherein all the active drug substances are fully dissolved in the formulation as well as the two or more active ...
Pharmaceutical compositions
Mexichem Amanco Holding S.a. De C.v.
February 02, 2017 - N°20170027867

A pharmaceutical solution for a medication delivery apparatus, especially a metered dose inhaler, is described. The pharmaceutical solution comprises: (a) a liquefied propellant component consisting essentially of and preferably consisting entirely of 1,1-difluoroethane (r-152a); (b) ethanol; and (c) a drug component dissolved in the propellant/ethanol mixture consisting of at least one drug selected from the group consisting of ...
Inhalation devices and systems and methods including the same
Fsc Laboratories, Inc.
January 26, 2017 - N°20170021118

A collapsible inhalation device for use with a metered dose inhaler (mdi) dispenser includes an outlet end member, an inlet end member and a tubular, pliable, collapsible sleeve member attached at either end to the inlet and outlet members. The outlet end member includes a mouthpiece. The inlet end member includes an inlet port and an mdi dispenser mount structure ...
Dose counter for metered dose inhaler
3m Innovative Properties Company
January 26, 2017 - N°20170021117

The present disclosure relates to a dose indicator comprising, a chassis comprising a chassis frame and a displacement portion comprising a drive part to engage an indexable first display unit indexable about a first display axis, the indexable first display unit comprising a drive tooth to drive an indexable second display unit indexable about a second display axis, the second ...
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Dose counter with lockout mechanism
Map Pharmaceuticals, Inc.
January 12, 2017 - N°20170007786

A medicament dispenser, in particular a metered dose inhaler, which is able to count the number of time the dispenser is activated and then disable the device, which then prevents any additional medicament from being dispensed. Additional embodiments include a medicament dispenser which are adapted to display either the number of activations that have occurred or the number of activations ...
Pharmaceutical compositions
Mexichem Amanco Holdings S.a. De C.v.
January 12, 2017 - N°20170007701

A pharmaceutical solution for a medication delivery apparatus, especially a metered dose inhaler, is described. The pharmaceutical solution comprises: (a) a liquefied propellant component consisting essentially of and preferably consisting entirely of 1,1-difluoroethane (r-152a); (b) ethanol; and (c) a drug component dissolved in the propellant/ethanol mixture consisting of at least one drug selected from the group consisting of ...
Compositions, methods & systems for respiratory delivery of two or more active agents
Pearl Therapeutics, Inc.
January 05, 2017 - N°20170000725

Compositions, methods and systems are provided for pulmonary or nasal delivery of two or more active agents via a metered dose inhaler. In one embodiment, the compositions include a suspension medium, active agent particles, and suspending particles, in which the active agent particles and suspending particles form a co-suspension within the suspension medium.
Levalbuterol salt
Sunovion Pharmaceuticals Inc.
December 22, 2016 - N°20160368858

Levalbuterol l-tartrate affords crystals possessing properties desirable for use in a metered dose inhaler.
Pressurised metered dose inhalers and method of manufacture
Cardiff Scintigraphics Limited
December 08, 2016 - N°20160354564

The invention relates to a method for the manufacture of a pressurised metered dose inhaler (pmdi) and components for use in said method, in particular, a pmdi compatible tablet (i. E. One that is able to be dispersed or disintegrates within a liquid phase, such as a propellant, used in a pmdi formulation) which contains at least one active pharmaceutical ...
Aerosol formulations comprising formoterol fumarate dihydrate
Jagotec Ag
October 27, 2016 - N°20160310452

The invention provides a method of producing a highly stable pharmaceutical aerosol suspension formulation suitable for use in a metered dose inhaler, the formulation comprising formoterol fumarate di-hydrate in suspension, a steroid in suspension, a propellant and ethanol, the method comprising the steps of drying the formoterol fumarate di-hydrate to a water content of 4. 8 to 4. 28%.
Stable pressurized aerosol solution composition of glycopyrronium bromide and formoterol combination
Chiesi Farmaceutici S.p.a
October 20, 2016 - N°20160303045

Aerosol solution compositions intended for use with a pressurized metered dose inhaler, comprising glycopyrronium bromide and formoterol, or a salt thereof or a solvate of said salt, optionally in combination with one or more additional active ingredients, and stabilized by a selected amount of a mineral acid, exhibit improved stability when contained in a can internally coated by a resin ...
Stable pressurized aerosol solution composition of glycopyrronium bromide and formoterol combination
Chiesi Farmaceutici S.p.a.
October 20, 2016 - N°20160303044

Aerosol solution compositions intended for use with a pressurized metered dose inhaler, comprising glycopyrronium bromide and formoterol, or a salt thereof, optionally in combination with one or more additional active ingredients, and stabilized by a selected amount of a mineral acid, exhibit improved stability when contained in an aerosol can provided with a metering valve having at least a butyl ...
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