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Metabolism patents

      

This page is updated frequently with new Metabolism-related patent applications.




 Apparatus and  brain training patent thumbnailApparatus and brain training
An apparatus and method for brain training, including at least one first vibratory stimulation unit configured to generate vibratory stimuli with the user's skull; at least one second vibratory stimulation unit configured to generate vibratory stimuli with the user's body movement senses; at least one brain wave detecting unit configured to detect the brain wave of the user; and a controlling unit configured to connect with and control the visual stimulation unit, the first vibratory stimulation unit, the second vibratory stimulation unit and the brain wave detecting unit. By using the apparatus, the user can trigger active different parts area of brain to respond to the stimulations in a non-invasive way to improve the metabolism of brain tissue and help the neurons-to-neurons communication, which would be used in different occasions to improve the learning ability of users..

 Method for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl trna synthetase patent thumbnailMethod for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl trna synthetase
The present invention relates to a novel function of lysyl trna synthetase, that is, lysyl trna synthetase interacts with 67lr through translocation of krs into plasma membrane, and so enhances tumor (or cancer) cell migration, thereby having an effect on cancer metastasis. More specifically, it relates to method for controlling cancer metastasis or cancer cell migration by modulating an cellular level of lysyl trna synthetase, an use of an expression vector comprising a construct inhibiting krs expression for preventing or treating cancer, an use of an agent inhibiting krs activity for preventing or treating cancer, a method for screening an agent which modulates cancer metastasis or cancer cell migration, a method for screening an agent inhibiting an interaction between krs and 67lr.
Medicinal Bioconvergence Research Center


 Determining cancer aggressiveness, prognosis and responsiveness to treatment patent thumbnailDetermining cancer aggressiveness, prognosis and responsiveness to treatment
The invention provides methods of determining the aggressiveness, prognosis and response to therapy for particular cancers, which include comparing the expression levels of one or a plurality of differentially expressed genes from one or more 5 functional metagenes, including a carbohydrate/lipid metabolism metagene, a cell signalling metagene, a cellular development metagene, a cellular growth metagene, a chromosome segregation metagene, a dna replication/recombination metagene, an immune system metagene, a metabolic disease metagene, a nucleic acid metabolism metagene, a post-translational modification metagene, a protein 10 synthesis/modification metagene and a multiple networks metagene. The method disclosed herein may be particularly suitable as a companion diagnostic for cancer therapies..
The Council Of The Queensland Institute Of Medical Research


 Genomic instability markers in fanconi anemia patent thumbnailGenomic instability markers in fanconi anemia
Markers for genomic instability in fanconi anemia (fa) and other pathologies for therapeutic and diagnostic uses. In one embodiment, glycosphingolipid metabolism is altered in the fa deficient squamous cell carcinoma (scc) cells, based on analysis of a metabolomics/lipidomics platform.
Children's Hospital Medical Center


 Compatible composition containing chinese medicine cichorium glandulosum boiss et hout as lipid-lowering active ingredient patent thumbnailCompatible composition containing chinese medicine cichorium glandulosum boiss et hout as lipid-lowering active ingredient
Disclosed are a compound pharmaceutical composition containing cichorium glandulosum boiss et hout as a lipid-lowering active ingredient and the use of the composition for preparing a drug for treating or preventing lipid metabolism disorders, wherein the composition comprises a pharmaceutically active ingredient and a pharmaceutically acceptable carrier, wherein the pharmaceutically active ingredient consists of quercetin-3-o-β-d-glucuronoside, isoquercitrin and quercetin at a molar ratio of 1.1-2.4:1.3-3.3:1.2-3.1.. .
Nanjing Ruiying Runze Biopharmaceutical Technology Co., Inc.


 Extracts of agricultural husks used to modify the metabolism of plants patent thumbnailExtracts of agricultural husks used to modify the metabolism of plants
The invention relates to a non-toxic composition prepared from agricultural waste, including steps of a) hydrolysing the plant matter in acidic conditions; b) nitrating the released phenolic compounds; c) stimulating the coupling between the phenolic compounds which are nitrated or not; d) insolubilizing and separating the coupled compounds; and e) drying the precipitated insoluble solids. The resulting composition, when applied to plants, has phytoregulating properties that induces favorable metabolic and physiological changes which promote increases in the mass of the roots and the photosynthetic capacity, in the resistance to biotic factors, in the tolerance to abiotic stress factors and/or in the productivity of the crops..

 Genetic based health management systems for weight and nutrition control patent thumbnailGenetic based health management systems for weight and nutrition control
Systems have been devised for health management based upon genetic markers. Specifically, systems are arranged to compute genetic risk for several factors relating to metabolism and weight gain in view of various genotypes at particular markers in an individual's genome.
Pathway Genomics Corporation


 Use of tanac2 protein and encoding gene thereof patent thumbnailUse of tanac2 protein and encoding gene thereof
The tanac2 gene can promote uptake and utilization of nitrogen in a plant. A method for improving the uptake, transport and/or assimilation of nitrogen element in the plant includes: introducing a gene encoding a protein represented by seq id no:4 into a primary plant to obtain a transgenic plant.
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences


 Method and composition for the treatment of opioid induced constipation patent thumbnailMethod and composition for the treatment of opioid induced constipation
The invention relates to a method of treatment using a solid oral pharmaceutical dosage form comprising an opioid receptor antagonist for use in the treatment of opioid induced constipation comprising the opioid antagonist equivalent to 24 mg of naloxone hydrochloride as twice daily formulation or equivalent to 48 mg of naloxone hydrochloride as once daily formulation, characterized in that the opioid antagonist has a rapid first pass metabolism with a plasma half-life of 2 hours or less in humans within the first 3 hours of oral administration of a solution, wherein the steady state pharmacokinetics result in a constant level of naloxone in the bloodstream, wherein the pharmacokinetics are independent of whether the dosage is administered once or twice daily, wherein the oral dosage form releases the opioid antagonist in a prolonged manner, wherein the in vitro release rate of the opioid antagonist measured using the paddle stirrer method according to ph. Eur.
Develco Pharma Schweiz Ag


 Method for detecting genes sensitive to low-level ionizing radiation, and gene detected by the method patent thumbnailMethod for detecting genes sensitive to low-level ionizing radiation, and gene detected by the method
A method for detecting genes sensitive to low-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to low-level ionizing radiation, discovered in a carcinogenic entity and verified in a normal entity are detected by subjecting a cancerous akr/j mouse and a normal icr mouse to low-level radiation.
Korea Hydro & Nuclear Power Co., Ltd.


Guanidine compounds and use thereof

The present invention relates to guanidine compounds for inhibiting mitochondrial oxidative phosphorylation (oxphos) and use thereof. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating a oxphos-related disease, particularly cancer, by inhibiting mitochondrial oxidative phosphorylation and reprogramming cellular metabolism..
Immunomet Therapeutics Inc.

Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses

The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, alzheimer's disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, syndrome x, thrombotic disorder. Compounds and methods of the invention can also be used to modulate c reactive protein or enhance bile production in a patient.
Esperion Therapeutics, Inc.

Memory improving composition, preparation method and use thereof

The present invention relates to the technical field of health food, and discloses a memory improving composition and the preparation method and use thereof. The composition is made from arillus longan, poria, semen nelumbinis, enzymatic extract of semen juglandis, phosphatidylserine and taurine.
Infinitus (china) Company Ltd.

Expression vector system comprising two selection markers

Wherein the activity of the selectable marker (sm i) or (sm ii) is at least partially influenced by the activity of the other selectable marker and wherein the selectable markers (sm i) and (sm ii) are involved in the folate metabolism. Also provided are suitable host cells, selection methods and methods for producing polypeptides with high yield..

Gene products of bacillus licheniformis which form odorous substances and improved biotechnological production methods based thereon

The present invention relates to 25 hitherto undescribed genes of b. Licheniformis and gene products derived thereform and all sufficiently homologous nucleic acids and proteins thereof.
Basf Se

Composition for imaging atherosclerosis and diagnosing atherosclerosis by using same

The present disclosure relates to a composition for imaging atherosclerosis and a method for diagnosing atherosclerosis using the same. The composition for imaging atherosclerosis according to the present disclosure shows excellent atherosclerosis diagnosis accuracy, enables diagnosis of atherosclerosis even for a person with diseases of glucose metabolism such as diabetes and enables effective diagnosis even for atherosclerosis occurring in the brain and heart.
Seoul National University R&db Foundation

Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof

The present invention provides novel compositions for the delivery of a hypnotic agent across the oral mucosa. In particular, the buffer system in the compositions of the present invention raises the ph of saliva to a ph greater than about 7.8, thereby facilitating the substantially complete conversion of the hypnotic agent from its ionized to its un-ionized form.
Paratek Pharmaceuticals, Inc.

Method for detecting genes sensitive to low-level ionizing radiation, and gene detected by the method

A method for detecting genes sensitive to low-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to low-level ionizing radiation, discovered in a carcinogenic entity and verified in a normal entity are detected by subjecting a cancerous akr/j mouse and a normal icr mouse to low-level radiation.
Korea Hydro & Nuclear Power Co., Ltd.

Method for detecting genes sensitive to low-level ionizing radiation, and gene detected by the method

A method for detecting genes sensitive to low-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to low-level ionizing radiation, discovered in a carcinogenic entity and verified in a normal entity are detected by subjecting a cancerous akr/j mouse and a normal icr mouse to low-level radiation.
Korea Hydro & Nuclear Power Co., Ltd.

Plant genes involved in nitrate uptake and metabolism

The present invention relates nucleic acid molecules that are modulated (e.g., upregulated) by nitrogen in corn, to proteins or polypeptides encoded by these nucleic acid molecules, and promoters of these nucleic acid molecules. The present invention relates to a nucleic acid construct having a nucleic acid molecule that is modulated by nitrogen in corn, as well as to expression systems, host cells, plants, and plant seeds having the nucleic acid construct.
Iowa State University Research Foundation, Inc.

Systems, apparatus, and methods related to modeling, monitoring, and/or managing metabolism

Systems, apparatus, and methods related to modeling, monitoring, and/or managing metabolism of a subject include measuring a respiratory quotient (rq) level in a subject and/or optimizing and executing a nonlinear feedback model to model energy substrate utilization in the subject based on at least one of a macronutrient composition and caloric value of food consumed by the subject, an intensity and duration of activity by the subject, a rate and maximum capacity of glycogen storage in the subject, a rate and maximum capacity of de novo lipogenesis in the subject, a quality and duration of sleep by the subject, and/or an rq level in the subject.. .
Massachusetts Institute Of Technology

Management of propionate metabolism disorders

Described is a nutritional formula, also referred to as a nutritional formulation, for dietary management of a propionic metabolism disorder, such as propionic acidemia.. .

Method for detecting genes sensitive to low-level ionizing radiation, and gene detected by the method

A method for detecting genes sensitive to low-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to low-level ionizing radiation, discovered in a carcinogenic entity and verified in a normal entity are detected by subjecting a cancerous akr/j mouse and a normal icr mouse to low-level radiation.
Korea Hydro & Nuclear Power Co., Ltd.

The production of hydrogen and other gaseous or liquid products in an accelerated bioprocess

Method and apparatus for the production of hydrogen and other gaseous or liquid substances (such as 2,3-butanediol) formed with the help of microbes in conditions where the normal microbial metabolism (catabolism and anabolism) has been restricted by ph or temperature, for example. Then carbon is not liberated into gaseous phase as fast as in more common microbial reactions.

Thermophilic and thermoacidophilic metabolism genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods

Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from alicyclobacillus acidocaldarius are provided. Further provided are methods for modulating or altering metabolism in a cell using isolated and/or purified polypeptides and nucleic acid sequences from alicyclobacillus acidocaldarius..
Battelle Energy Alliance, Llc

Novel alpha-galactosidase a derivatives

Fabry disease is a rare (incidence approximately 1 in 20,000) x-linked inborn error of glycolipid metabolism caused by a deficiency of the lysosomal enzyme, α-galactosidase a, that leads to early death in affected males due to occlusive disease of the heart, kidney, and brain. The present invention provides a modified alpha-galactosidase a enzyme derivative with improved stability and catalytic properties.
Research Foundation Of The City University Of New York

Hepcidin mimetic peptides and uses thereof

Compounds and methods are described herein that can be used to treat subjects for conditions related to hepcidin activity, such as but not limited diseases of iron metabolism, beta thalassemia, hemochromatosis, iron-loading anemias, alcoholic liver disease, or chronic hepatitis c.. .
Merganser Biotech, Inc.

Certain chemical entities, compositions, and methods

Chemical entities that are effective as kinase inhibitors, pharmaceutical compositions and methods of treatment are disclosed. The chemical entities disclosed specifically inhibit signal transduction and cellular proliferation by modulating the activity of protein kinases to regulate and modulate abnormal or inappropriate cell proliferation, differentiation, or metabolism.
Neupharma, Inc.

Mitochondrial-derived peptide mots3 regulates metabolism and cell survival

Mots3 is a novel polypeptide. Methods of treating diseases such as diabetes, obesity, fatty liver, and cancer using mots3 and pharmaceutical compositions thereof are disclosed herein..
The Regents Of The University Of California

Method for medical treatment

The disclosure provides improved methods for treating or preventing a class of undesired health events including multiple related maladies, such as a disease, condition, or syndrome or the like. The improvement results from optimization of energy metabolism by administering a therapeutically effective compound selected to a) modulate mitochondrial activity to correct for deficiencies resulting from the disease, b) to boost cell energy metabolism thereby improving the original method's efficacy, and/or c) to correct for metabolic disruptions resulting from therapies or medicaments used in the method to be improved.

Physiological sensors, systems, kits and methods therefor

A combination physiologic status sensor system is described. It integrates a highly efficient reflectance oximeter, acquisition of a 2-lead electrocardiogram (“ecg”) heart rate signal, a photonic indicator of molecular products of anaerobic metabolism, and a skin temperature sensor.
Reveal Biosensors, Inc.

Health care apparatus and operating the same

A health care apparatus and a method of operating the same is provided. The method may include: generating a temperature waveform from a skin temperature of a user; determining, from the generated temperature waveform, a dietary temperature waveform based on food; and determining, from the dietary temperature waveform, diet metabolism information of the user..
Samsung Electronics Co., Ltd.

Systems, apparatus, and methods for analyzing and predicting cellular pathways

Integrative analysis of metabolites is essential to obtain a comprehensive view of dysregulated biological pathways leading to a disease. Despite the great potential of metabolites their system level analysis has been limited.

Methods for improving fertility and selectivity for desired offspring sex in artificial insemination

A method for providing semen optimized for use in artificial insemination is described. Methods involve monitoring sperm cell metabolism by assays that produce results in real time, while sperm are still being processed into doses for use in insemination.

Novel prodrugs and methods of use thereof

The invention relates to compounds of use as targeted cytotoxic agents and methods of use thereof. In particular, the invention relates to prodrugs that are substantially resistant to human akr1c3 enzyme metabolism, methods of cell ablation using said compounds and methods of treatment of cancer and other hyperproliferative disorders using said compounds..
Health Innovation Ventures B.v.

Methods targeting mir-128 for regulating cholesterol/lipid metabolism

Methods for targeting microrna 128 (mir-128) for regulating cholesterol/lipid metabolism and insulin sensitivity.. .
The General Hospital Corporation

Preparation for improving the action of receptors

The present invention relates to the use of polyunsaturated fatty acids and one or more components which have a beneficial effect on total methionine metabolism selected from the group consisting of vitamin b 12 and precursors thereof, vitamin b6 and derivatives thereof, folic acid, zinc and magnesium, in the manufacture of a preparation for improving the action of receptors. This preparation is advantageously applied in patients suffering from parkinson's disease, huntington's chorea, epilepsy, schizophrenia, paranoia, depression, sleep disorders, impaired memory function, psychoses, dementia and adhd..
N.v. Nutricia

Horizontal single use pressurizable modular multi-atitator microbial fermentor

A scalable horizontal single use pressurizable modular multi-agitated portable fermentor for culturing microorganisms is provided. The fermentor is suitable for use in laboratories, research and development facilities and large scale production facilities, particularly modular portable clean room facilities.

Pyrimidine compound and medical use thereof

Wherein each symbol is as defined in the specification and a method of therapeutically or prophylactically treating an undesirable cell proliferation, comprising administering such a compound. The compound of the present invention has superior activity in suppressing undesirable cell proliferation, particularly, an antitumor activity, and is useful as an antitumor agent for the prophylaxis or treatment of cancer, rheumatism, and the like.

Tubular container having applicator

The present invention disclosed herein relates to a tubular container having an applicator. According to the tubular container having an applicator, an applicator made of metal material that comes into contact with the skin is disposed at an upper portion of the tubular container, such that it is possible to transfer warmth and coldness to the skin when contents are applied, thereby promoting the metabolism and elasticity of the skin..
Yonwoo Co., Ltd.

Compositions and methods for controling carbohydrate and fat metabolism

This composition is particularly useful as a nutritional product or health product for preventing and/or combating carbohydrate and/or fat metabolism disorders in humans and animals.. .

Nutritional compositions

In some aspects, the disclosure relates to compositions useful for the dietary management of inborn errors of metabolism (e.g., pku, msud, hcu, iva, and mma/pa). In some embodiments, the disclosure provides a composition comprising a protein source, a fat source, a carbohydrate source, at least one vitamin, and at least one mineral, wherein the protein source comprises at least six free amino acids.
Cambrooke Therapeutics, Inc.

Methods of treating coronavirus infection

The present invention provides methods for treating a coronavirus infection. For example, treatment may be effected by administering a neurotransmitter inhibitor, a signaling kinase inhibitor, an estrogen receptor inhibitor, a dna metabolism inhibitor or an anti-parasitic agent.
United States Government As Represented By The Secretary, Department Of Health And Human Services

Methods for sterilization and/or disinfection

Methods for killing spores include contacting the spores with an aqueous solution containing performic acid. The contacting occurs at a temperature of less than or equal to about 35° c.
Performance Packaging Of Nevada, Llc

Animal cell culture medium and culture container

A culture medium for animal cells for enhancing a metabolism activity of the tca cycle (tricarboxylic acid cycle) in respiration of the animal cells includes, as effective components, amino acids metabolized to succinyl coa that is an element constituting the tca cycle at a concentration of 2.3 mmol/l to 6.0 mmol/l.. .
Toyo Seikan Group Holdings, Ltd.

Micro- and nano-quantity sleep enhancing nutrient composition and enhancing central nervous system protein clearance using same

The present invention relates to a dietary supplement, composition, nutraceutical, and/or system for inducing or treating biological responses or conditions (namely sleep or sleep disorders) which utilize ultra-low dosage amounts of vitamins, minerals, amino acids, co-enzymes, stimulants, and/or similar ingredients in a highly bio-active delivery system which bypasses first pass metabolism. In particular, the present invention relates to a nutraceutical composition/formulation which substantially bypasses first pass metabolism and such as, but not limited to, activation of the glymphatic system to facilitate clearance of neuronal metabolites from the csf and interstitial fluids in the brain..
Foundational Biosystems, Llc

Cosmetic uses of swertiamarin

The present invention relates to the uses of swertiamarin or of a plant extract enriched with swertiamarin, for stimulating the formation or regeneration of the epidermis and/or for stimulating the metabolism of the dermis mainly in the cosmetics field.. .
Lucas Meyer Cosmetics



Metabolism topics:
  • Metabolism
  • Antibodies
  • Vascular Disease
  • Lipoprotein
  • C Syndrome
  • Pancreatitis
  • Metabolic Syndrome
  • Dyslipidemia
  • Cardiovascular Disease
  • Cardiovascular
  • Recombinant
  • Differentiation
  • Modulation
  • Ubiquitination
  • Hypertension


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    This listing is a sample listing of patent applications related to Metabolism for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Metabolism with additional patents listed. Browse our RSS directory or Search for other possible listings.


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