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Metabolism-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).

Method for treating, stabilizing or slowing down brain glucose metabolism deficit
N.v. Nutricia
June 08, 2017 - N°20170157163

The invention pertains to the use of (i) one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof, and (ii) a lipid fraction comprising at least one of docosahexaenoic acid (22:6; dha), eicosapentaenoic acid (20:5; epa) and docosapentaenoic acid (22:5; dpa), or esters thereof in the manufacture of a composition for use in a method for treating, stabilizing ...
Methods and compositions for treatment of disorders associated with damage induced by free radicals
Glycadia, Inc.
June 08, 2017 - N°20170157010

The present invention relates to treatment of various disorders, diseases or conditions associated with or mediated by oxidative stress arising from an imbalance between the production of and the ability to neutralize reactive free radicals. The present invention is directed to methods and compositions capable of scavenging reactive free radicals for therapeutically or prophylactically treating disorders associated with free radical-induced ...
A method of screening for a compound capable of stimulating glucose transport into brown and/...
Atrogi Ab
June 01, 2017 - N°20170153225

A method of screening for a candidate compound for use in the treatment of a condition involving dysregulation of metabolism in a mammal by identifying a compound capable of stimulating de novo synthesis of glut1 (glucose transporter 1) in brown and/or brite adipocytes of the mammal and/or capable of stimulating translocation of glut1 in brown and/or brite adipocytes ...
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Metabolism Patent Applications
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Oxygenation mask with integrated end-tidal carbon dioxide monitoring
B&t Healthcare Solutions Llc
June 01, 2017 - N°20170151406

Various embodiments are directed to oxygenation masks having a plurality of tubes detachably secured to the oxygenation mask, wherein the plurality of tubes comprise an oxygen tube configured to supply oxygen gas received from an oxygen source to the patient via the oxygenation mask and an end-tidal carbon dioxide return tube configured to direct a portion of the patient's exhaled ...
Buprenorphine nanoparticle composition and methods thereof
Auburn University
June 01, 2017 - N°20170151180

Stable nanoparticle compositions comprising buprenorphine and at least one biodegradable polymer. The disclosure also provides methods of controlling pain in an animal and methods of treating addiction in a human utilizing the stable nanoparticle compositions, as well as pharmaceutical formulations comprising the stable nanoparticle compositions. The stable nanoparticle compositions are capable of releasing buprenorphine over several days, weeks, or months ...
Infant nutrition with lipid globules to increase energy expenditure and metabolic flexibility later in life
N.v. Nutricia
June 01, 2017 - N°20170151175

The present invention relates to nutrition for infants and young children with particular lipid globules, resulting in programming the metabolism to an increased energy expenditure and improved mitochondrial functioning later in life when exposed to a high fat, high energy diet.
Metabolism Patent Pack
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Metabolism Patent Applications
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  • 177+ full patent PDF documents of Metabolism-related inventions.
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Antibody to gdf8 and uses thereof
N.v. Nutricia
May 25, 2017 - N°20170145084

The disclosure provides novel molecules related to growth and differentiation factor-8 (gdf8), in particular epitopes specific to gdf8 and other specific antagonists of gdf8 in particular anti-gdf8 antibodies or antigen binding protein or fragment thereof which may inhibit gdf8 activity and signal in vitro and/or in vivo. The disclosure also provides for an immunoassay used to detect and quantitate ...
Carbohydrate metabolism-ameliorating agent
N.v. Nutricia
May 25, 2017 - N°20170143701

Provided is a safe carbohydrate metabolism-ameliorating agent having an excellent carbohydrate metabolism-ameliorating action, and a safe glp-1 secretion accelerator having an excellent glp-1 secretion-accelerating action. The carbohydrate metabolism-ameliorating agent or glp-1 secretion accelerator according to the present invention, which contains a specific cyclic dipeptide or a salt thereof as an active ingredient, is advantageous in that it has an excellent ...
Physiogenomic method for predicting drug metabolism reserve for antidepressants and stimulants
Genomas, Inc.
May 18, 2017 - N°20170137886

Disclosed herein are compositions and methods relevant to a novel drug metabolism reserve physiotype to determine the metabolic capacity of a human individual. The drug metabolism reserve physiotype allows the determination of the innate metabolic capacity of the patient relevant to antidepressant and stimulant treatment and can be predicted and diagnosed simply from a blood sample. In the disclosed method, ...
Recombinant cells and methods for nonphosphorylative metabolism
Regents Of The University Of Minnesota
May 18, 2017 - N°20170137855

This disclosure describes methods for screening heterologous coding regions (e. G., a single gene coding region, and operon, or other gene cluster) for the ability to genetically modify a host cell to perform nonphosphorylative biosynthesis of 2,5-dioxopentanoate and downstream derivatives thereof (e. G., 1,4-butanediol, glutamate, or glutaconate. This disclosure further describes recombinant cells modified to increase nonphosphorylative biosynthesis of 2,5-dioxopentanoate ...
Organic compositions to treat apoc3-related diseases
Arrowhead Pharmaceuticals, Inc.
May 18, 2017 - N°20170137814

The present disclosure relates to compositions and methods for treating apoc3-related diseases such as: hypertriglyceridemia (e. G., type v hypertriglyceridemia), abnormal lipid metabolism, abnormal cholesterol metabolism, atherosclerosis, hyperlipidemia, diabetes, including type 2 diabetes, obesity, cardiovascular disease, and coronary artery disease, among other disorders relating to abnormal metabolism or otherwise, using a therapeutically effective amount of a rnai agent to apoc3.
Mouth rinse for prevention of periodontal disease
Arrowhead Pharmaceuticals, Inc.
May 18, 2017 - N°20170135934

The present invention causes the tissues in the gingiva to be less permeable to the products of bacterial metabolism produced from dental plaque. In addition, chemicals derived from the ingestion of foods and beverages are blocked from entry into the gingival tissues. This results in the prevention of oral infections and, most importantly, the loss of teeth. In addition to ...
Agents and mechanisms for treating hypercholesterolemia
Arrowhead Pharmaceuticals, Inc.
May 18, 2017 - N°20170135391

A method of treating hypercholesterolemia in mammals, by administering an effective amount of a microbial fermentation product, and regulating genes involved in lipoprotein metabolism. A method of regulating cholesterol levels in a patient by administering an effective amount of a composition chosen from the group consisting of paz, specific components isolated from paz, chemically synthesized analogues of the components of ...
Metabolism Patent Pack
Download 177+ patent application PDFs
Metabolism Patent Applications
Download 177+ Metabolism-related PDFs
For professional research & prior art discovery
  • 177+ full patent PDF documents of Metabolism-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Dynamic knockdown of central metabolism for redirecting glucose-6-phosphate fluxes
Massachusetts Institute Of Technology
May 11, 2017 - N°20170130210

Described herein are methods for dynamic redirection of metabolic flux in a cell from central metabolism towards production of heterologous products.
Method of treating hyperlipidemia and atherosclerosis with mir-30c
The Research Foundation For The State University Of New York
May 04, 2017 - N°20170121713

This disclosure provides a novel role for microrna (mir) regulation of lipid metabolism via the mtp pathway, leading to reductions in apob secretion and blood lipid levels. Mir regulation of the mtp pathway is shown herein to reduce hyperlipidemia and atherosclerosis in vivo. Therefore, inhibition of mtp expression and activity by mir regulation is identified as a new therapeutic target ...
Compositions and methods for rapid and dynamic flux control using synthetic metabolic valves
Duke University
May 04, 2017 - N°20170121707

This invention relates to metabolically engineered microorganisms, such as bacterial and or fungal strains, and bioprocesses utilizing such strains. These strains enable the dynamic control of metabolic pathways, which can be used to optimize production. Dynamic control over metabolism is accomplished via a combination of methodologies including but not limited to transcriptional silencing and controlled enzyme proteolysis. These microbial strains ...
Lipid metabolism and/or sugar metabolism improver containing lactic acid bacterium or treatment product thereof
Asahi Group Holdings, Ltd.
May 04, 2017 - N°20170119828

This invention provides the use of a microorganism capable of improving both lipid metabolism and sugar metabolism. Specifically, the invention relates to: a lipid metabolism and/or sugar metabolism improver comprising, as an active ingredient, a bacterial cell selected from bacteria belonging to the genus lactobacillus and the genus bifidobacterium, a treated product of the bacterial cell, or a mixture ...
Method for improving pharmacokinetics
Roche Palo Alto Llc
May 04, 2017 - N°20170119739

The object of the present invention is to inhibit oxidative metabolism of a compound of formula i by co-administration with ritonavir, a cytochrome p450 inhibitor.
Compounds influencing fatty acid uptake and metabolism and the production of inflammatory agents and methods ...
The Hershey Company
May 04, 2017 - N°20170119729

The invention provides compounds and plant extract compositions that inhibit pancreatic enzymes, such as lipases and amylases, and most particularly pancreatic lipase and phospholipase a2 (pla2), and cox-2 enzyme, and improve the inflammatory state or response conditions in animals. The compounds and plant extracts can be used in methods and administration regimens to treat animals for obesity-related conditions, diabetes and ...
Homogeneous formulation comprising omega-3 polyunsatured fatty acid and resveratrol for oral administration
Sigma-tau Industrie Farmaceutiche Riunite S.p.a.
May 04, 2017 - N°20170119720

The present invention relates to homogeneous formulations comprising omega-3 polyunsaturated fatty acids (n-3 pufa) and resveratrol for oral administration, in which the resveratrol is solubilized in a solvent system consisting of omega-3 polyunsaturated fatty acids (n-3 pufa), or their alkyl esters, and a ionic emulsifier. The composition according to the present invention can be formulated as food or nutritional supplement ...
Regulation of glucose metabolism using anti-cgrp antibodies
Alderbio Holdings Llc
April 27, 2017 - N°20170114122

The present disclosure provides methods for the prevention or treatment of metabolic disorders. In exemplary embodiments, methods of administering an anti-cgrp antibody are provided, optionally in combination with a second agent, wherein peripheral and/or hepatic glucose utilization is increased, thereby preventing or treating diseases and disorders associated with insulin resistance. Compositions comprising an anti-cgrp antibody are also provided, optionally ...