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Metabolism

Metabolism-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Methods for treating hyperlipidemia with an angptl8 inhibitor and an angptl3 inhibitor
Regeneron Pharmaceuticals, Inc.
October 12, 2017 - N°20170291937

The present invention provides methods for treating patients suffering from hyperlipidaemia, wherein the patient is non-responsive to, inadequately controlled by, or intolerant to treatment with a standard lipid modifying therapy. The methods of the invention provide for lowering at least one lipid parameter in the patient by administering a therapeutically effective amount of an antibody or antigen-binding fragment thereof that ...
Plasminogen activator inhibitor-1 inhibitors and methods of use thereof
Eastern Michigan University
October 12, 2017 - N°20170291893

The invention relates to plasminogen activator-1 (pai-1) inhibitor compounds and uses thereof in the treatment of any disease or disorder associated with elevated pai-1. The invention includes, but is not limited to, the use of such compounds to prevent or reduce thrombosis and fibrosis, to promote thrombolysis, and to modulate lipid metabolism and treat diseases or disorders associated with elevated ...
Reprogramming cells
The Scripps Research Institute
October 05, 2017 - N°20170283776

The present invention provides for methods, compositions, and kits for producing an induced pluripotent stem cell from a non-pluripotent mammalian cell using a 3′-phosphoinositide-dependent kinase-1 (pdk1) activator or a compound that promotes glycolytic metabolism as well as other small molecules.
Metabolism Patent Pack
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Metabolism Patent Applications
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  • 177+ full patent PDF documents of Metabolism-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Metabolism probes for therapy and diagnosis
Vanderbilt University
October 05, 2017 - N°20170283387

Novel 2-substituted glutamylanides useful as modulators of asct2 inhibitors. Compounds of the present invention can be used to treat patients suffering from diseases caused or influenced by abnormal asct2 transporter dysfunction.
Peptide and method for reducing the phosphate requirement and excretiion from farm animals
Wisconsin Alumni Research Foundation
October 05, 2017 - N°20170281741

Disclosed are methods of altering metabolism of phosphate in a livestock via an antibody. The methods involve the development of an antibody against fgf-23 for the purpose of reducing phosphate excretion by an animal.
Cyclic urea compounds as tropomyosin-related kinase (trk) inhibitors
Genzyme Corporation
October 05, 2017 - N°20170281641

Tropomyosin-related kinase inhibitors (trk inhibitors) are small molecule compounds useful in the treatment of disease. Trk inhibitors can be used as pharmaceutical agents and in pharmaceutical compositions. Trk inhibitors are useful in the treatment of inflammatory diseases, autoimmune disease, defects of bone metabolism and/or cancer, and are particularly useful in the treatment of osteoarthritis (oa), pain, and pain associated ...
Metabolism Patent Pack
Download 177+ patent application PDFs
Metabolism Patent Applications
Download 177+ Metabolism-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Metabolism-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Enhanced erythropoiesis and iron metabolism
Fibrogen, Inc.
September 21, 2017 - N°20170267641

The present invention relates to methods and compounds for regulating or enhancing ethropoiesis and iron metabolism, and for treating or preventing iron deficiency and anemia of chronic disease.
Methods for increasing intracellular activity of hsp70
Orphazyme Aps
September 21, 2017 - N°20170266263

The present invention relates to a bioactive agent capable of increasing the intracellular concentration and/or activity of hsp70 for use in the treatment of a lysosomal storage disease which arise from a defect in an enzyme whose activity is not directly associated with the presence of lysosomal bmp as a co-factor; such as glycogen storage diseases, gangliosidoses, neuronal ceroid ...
Methods and compositions for weight control
4life Patents, Llc
September 21, 2017 - N°20170266249

Methods and compositions for providing control over a subject's body, include methods and compositions for enhancing the ability of a subject's body to lose weight, or for inducing weight loss in the subject's body. Such methods and compositions may induce thermogenesis in the adipocytes of a subject's body, enhancing the subject's metabolism, inhibit adipogenesis in adipocytes of the individual, and ...
A novel synergistic herbal formulation for degenerative disease cardiovascular diseases, autoimmune, inflammatory and metabolism disorder ...
4life Patents, Llc
September 21, 2017 - N°20170266247

The present invention relates to a novel synergistic herbal formulation for degenerative disease, cardiovascular diseases, autoimmune, inflammatory and infectious diseases and metabolism disorder etc. Of man, animal and plants more particularly, the present invention relates to the herbal formulation for degenerative disease, cardiovascular diseases, autoimmune, inflammatory and infectious diseases etc which is prepared by using preparation of pongamia pinnata, dalbergia ...
Method for treating alzheimer's disease and 2, 3-biphosphoglycerate metabolism disorder induced
National Sun Yat-sen University
September 21, 2017 - N°20170266154

The present invention relates to a method for treating alzheimer's disease and 2,3-bpg metabolic disorder induced morbidities, comprising administrating a phthalide compound to an alzheimer's disease patient or a patient having 2,3-bpg metabolic disorder induced morbidities, wherein the method is characterized by that the phthalide compound has the same effect as 2,3-bpg on modulating hemoglobin to reduce its oxygen affinity ...
Palatable compositions including sodium phenylbutyrate and uses thereof
Acer Therapeutics Inc.
September 21, 2017 - N°20170266115

The present invention features palatable pharmaceutical compositions including sodium phenylbutyrate and methods for the treatment of inborn errors of metabolism (e. G., maple syrup urine disease or urea cycle disorders), neurodegenerative disorders such as parkinson's disease, spinal muscular atrophy, dystonia, or inclusion-body myositis with such compositions.
Thienopyrroles as histone demethylase inhibitors
Istituto Europeo Di Oncologia S.r.l.
September 14, 2017 - N°20170260197

The present application relates to thienopyrrole derivatives, compounds of formulas (i) and (ia), wherein r, r1, r2 and r3 are as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy. The compounds of the application can be useful for inhibiting kdm1 and the prevention and/or treatment of cancer, infectious disease, or a disease ...
Metabolism Patent Pack
Download 177+ patent application PDFs
Metabolism Patent Applications
Download 177+ Metabolism-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Metabolism-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Methods for treating patients with hyperlipidemia by administering a pcsk9 inhibitor in combination with an ...
Regeneron Pharmaceuticals, Inc.
September 07, 2017 - N°20170253666

The present invention provides methods for treating patients suffering from hypercholesterolemia, wherein the patient is non-responsive to, inadequately controlled by, or intolerant to treatment with a standard lipid modifying therapy. The methods of the invention provide for lowering at least one lipid parameter in the patient by administering a therapeutically effective amount of an antibody or antigen-binding fragment thereof that ...
Psma-related therapies
Memorial Sloan Kettering Cancer Center
September 07, 2017 - N°20170252433

The present invention provides methods of treating disease by modulation of psma activity. Such modulations can lead to, for example, alterations in cancer tumor metabolism, oxygenation, vascularization, and metastasis. The present invention encompasses the recognition that psma, through its role in a complex signaling cascade, can affect cancer progression, angiogenesis, and neovascularization. The present invention provides, among other things, methods ...
Therapeutic method and medicament for cancer patients by folr1-targeting drug and an antagonist for ...
Kyowa Hakko Kirin Co., Ltd
August 31, 2017 - N°20170247449

The invention provides a method for treating a cancer with a human folr1-targeting drug by increasing an expression of folate receptor α (hereinafter abbreviated to folr1) by using an antagonist for folic acid metabolism, a medicament for a cancer containing a human folr1-targeting drug for increasing an expression of folr1 by using an antagonist for folic acid ...
Quinolinone compound and use thereof
Sunshine Lake Pharma Co., Ltd.
August 31, 2017 - N°20170247332

Provided herein are a quinolinone compound, pharmaceutical composition thereof, and use of the compound or the pharmaceutical composition in drug preparation, the drug being used to prevent, manage, treat or relieve diseases related to hif and/or epo of a patient, including anemia, vascular disease, myocardial ischemia, dysmetabolism, or for wound healing.
Compositions and methods of use for treating metabolic disorders
Ngm Biopharmaceuticals, Inc.
August 31, 2017 - N°20170246249

Methods of treating individuals with a glucose metabolism disorder and/or a body weight disorder, and compositions associated therewith, are provided.
Extracts of nannochloropsis sp. and their applications
Cutech Srl
August 31, 2017 - N°20170246229

New extracts of nannochloropsis sp. And related species of nannochloropsis are suggested, obtainable by treating said microalgae with a solvent selected from the group consisting of c1-c1 aliphatic alcohols, ethyl acetate, water or their mixtures, removing the dissolved extracts from the residues and recovering the pure extracts from the solvent. The extracts show excellent properties particularly in modulating the ...
Compositions and methods for treating microbial infections
Vanderbilt University
August 31, 2017 - N°20170246149

Embodiments of the presently-disclosed subject matter include activators of hssrs that induce endogenous heme biosynthesis by perturbing central metabolism. These molecules are toxic to fermenting s. Aureus, including clinically relevant small colony variants (scvs). The utility of targeting fermenting bacteria is exemplified by the fact that this compound prevents the emergence of antibiotic resistance, enhances phagocyte killing, and reduces s. ...
Biocatalytic processes and materials for enhanced carbon utilization
Invista North America S.a.r.l.
August 24, 2017 - N°20170240936

The present disclosure describes biocatalytic processes for producing a product, comprising providing an aqueous stream (as) comprising at least one fermentable substrate and a gaseous stream (gs) comprising at least one of co2/h2, h2, methane, and/or co to a fermentation zone, wherein the gs and as stream are optionally contacted and/or mixed; the fermentation zone comprising at ...
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