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Metabolic Syndrome

Metabolic Syndrome-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Nutritional compositions containing butyrate and uses thereof
Mead Johnson Nutrition Company
June 14, 2018 - N°20180160714

Provided are nutritional compositions containing dietary butyrate. Further disclosed are methods for reducing the incidence of obesity and metabolic syndrome in a target subject via administering the nutritional composition containing dietary butyrate to the target subject.
Compounds as peptidic glp1/glucagon/gip receptor agonists
Sanofi
June 07, 2018 - N°20180155407

The present invention relates to trigonal glp-1/glucagon/gip receptor agonists and their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as for reduction of excess food intake.. .
Compounds as peptidic trigonal glp1/glucagon/gip receptor agonists
Sanofi
June 07, 2018 - N°20180155406

The present invention relates to trigonal glp-1/glucagon/gip receptor agonists and their medical use, for example in the treatment of disorders of the metabolic syndrome, including diabetes and obesity, as well as for reduction of excess food intake.. .
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Methods and compositions for treating diabetes, metabolic syndrome and other conditions
Cortendo Ab (publ)
June 07, 2018 - N°20180153883

Pharmaceuticals compositions comprising the 2s, 4r, ketoconazole enantiomer or its pharmaceutically acceptable salts, hydrates, and solvates, that are substantially free of the 2r, 4s ketoconazole enantiomer are useful to reduce cortisol synthese and for the treatment of type 2 diabetes, hyperglycemia, obesity, insulin resistance, dyslipidemia, hyperlipidemia, hypertension, metabolic syndrome, and other diseases and conditions, including but not limited to cushing's syndrome, ...
Bisamide derivative of dicarboxylic acid as an agent for stimulating tissue regeneration and recovery of ...
Obschestvo S Ogranichennoi Otvetstvennostiyu "pharmenterprises"
May 31, 2018 - N°20180147184

The invention relates to the field of medicine and concerns an agent that stimulates tissue regeneration and the recovery of diminished tissue and organ function. A medicinal agent for the treatment and/or prophylaxis of a pathological condition selected from the group including metabolic syndrome, impaired glucose tolerance, hepatitis, particularly chronic hepatitis and toxic hepatitis, idiopathic pulmonary fibrosis (ipf), emphysema ...
A method for predicting the risk of incidence of chronic kidney diseases
Sphingotec Gmbh
May 10, 2018 - N°20180128838

The present invention relates to means and methods suitable for risk prediction of chronic kidney disease (ckd) using pro-enkephalin or fragments thereof as biomarker. The risk prediction methods of the invention are intended for healthy subjects and for subjects suffering from diseases such as hypertension, cardiovascular diseases and events, diabetes, metabolic syndrome, obesity, or autoimmune diseases.
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Cyclic peptide tyrosine tyrosine compounds as modulators of neuropeptide y receptors
May 10, 2018 - N°20180127476

Z4, z7, z9, z11, z22, z23, z26, z30, z34, z35, p, m, n, q, and bridge are defined in the specification. The invention also relates to pharmaceutical compositions and methods for use thereof.
Probiotic compositions for improving metabolism and immunity
New York University
May 10, 2018 - N°20180125900

The application relates to methods based on modulating mammalian intestinal microbiota and related probiotic and prebiotic compositions. Specifically, the application relates to the use of novel bacterial genera ileibacterium and dubosiella, including their species i.
Compositions, methods of treatment and diagnostics for treatment of hepatic steatosis alone or in combination ...
Volant Holdings Gmbh
May 10, 2018 - N°20180125870

The present invention is directed to pharmaceutical compositions and methods of treatment that relate to the inhibition, resolution and/or prevention of an array of the manifestations of metabolic syndromes, including type 2 diabetes, hyperlipidemia, weight gain, obesity, insulin resistance, hypertension, atherosclerosis, fatty liver diseases and certain chronic inflammatory states that lead to these manifestations, among others. In additional aspects, the ...
Methods and formulations for modulating lyn kinase activity and treating related disorders
Melior Pharmaceuticals I, Inc.
May 10, 2018 - N°20180125845

The present invention relates to compounds and pharmaceutically acceptable salts thereof and formulations comprising the compounds or a pharmaceutically acceptable salts thereof that are useful in modulating lyn kinase activity. In particular, the compounds or a pharmaceutically acceptable salts thereof are useful for treating or preventing a disease or disorder including cardiovascular disease, dyslipidemia, dyslipoproteinemia, a disorder of glucose metabolism, ...
Induced expression of brain derived neurotrophic factor (bdnf) for treatment of neuromuscular, neurodegenerative, autoimmune, developmental ...
Mitochon Pharmaceuticals, Inc.
May 10, 2018 - N°20180125794

A method of treating a host of neuromuscular, neurodegenerative, developmental, autoimmune and metabolic diseases/disorders related to aging, such as traumatic injury, stroke, huntington's disease, epilepsy, multiple sclerosis (ms), lupus, type-1 and type-2 diabetes, maturity onset diabetes of the young (mody), myasthenia gravis (mg), rheumatoid arthritis (ra), graves' disease, guillain-barré syndrome (gb s), metabolic syndrome, muscular dystrophy or duchenne ...
Peptide analogs for treating diseases and disorders
Keybioscience Ag
April 19, 2018 - N°20180105568

Provided herein are methods for the treatment of type i diabetes, type ii diabetes, metabolic syndrome, or obesity, or of appetite suppression, or for mitigating insulin resistance, or for reducing an undesirably high fasting serum glucose level, or for reducing an undesirably high peak serum glucose level, or for reducing an undesirably high peak serum insulin level, or for reducing ...
Methods for preventing or treating metabolic syndrome
Cornell University
April 19, 2018 - N°20180104304

The invention provides methods of preventing or treating metabolic syndrome in a mammalian subject. The methods comprise administering to the subject an effective amount of an aromatic-cationic peptide to subjects in need thereof..
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Diagnostics and methods for treatment of non-alcoholic hepatic steatosis and hepatic steatohepatitis, and prevention of ...
Volant Holdings Gmbh
April 12, 2018 - N°20180099001

The present invention is directed to a system characterization of nash that combines modeling and biomarkers, enabling pharmaceutical compositions and methods of treatment that relate to the inhibition, resolution and/or prevention of non alcoholic fatty liver disease (nafld) and non alcoholic steatohepatitis (nash). Said conditions are liver related complications among the array of manifestations of metabolic syndromes, including type 2 ...
Methods of treating pediatric metabolic syndrome
Amarin Pharmaceuticals Ireland Limited
March 29, 2018 - N°20180085334

In various embodiments, the present invention provides methods of treating and/or preventing pediatric metabolic syndrome comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.. .
Animal models for cardiomyopathy
Recombinetics, Inc.
March 29, 2018 - N°20180084767

Genomically modified livestock animals having a modification in one or more genes implicated in heart failure are provided. The animals provide models for various pathologies in heart failure including dilated cardiomyopathy and hypertrophic cardiomyopathy and can be used for investigation of new treatment methods including interventional devices, biologics and pharmaceuticals.
Inhibitors of histone deacetylase
March 15, 2018 - N°20180072671

Or a pharmaceutically acceptable salt, hydrate, solvate, or prodrug thereof, wherein x1, x2, x3, x4, x5, w1, w2, w3, and w4 are as described herein. The present invention relates generally to inhibitors of histone deacetylase and to methods of making and using them.
Carbazole-containing sulfonamides as cryptochrome modulators
Reset Therapeutics, Inc.
March 15, 2018 - N°20180071306

The subject matter herein is directed to carbazole-containing sulfonamide derivatives and pharmaceutically acceptable salts or hydrates thereof of structural formula i wherein the variable r1, r2, r3, r4, r5, r6, r7, a, b, c′, d, e, f, g, h′, a, and b are accordingly described. Also provided are pharmaceutical compositions comprising the compounds of formula i to treat ...
Methods of preventing progression to type 2 diabetes mellitus
Vivus, Inc.
March 01, 2018 - N°20180055818

The present invention provides compositions and methods for delaying or preventing progression to type 2 diabetes mellitus in individuals with prediabetes and metabolic syndrome.. .
Treating conditions associated with metabolic syndrome
Tla Targeted Immunotherapies Ab
February 22, 2018 - N°20180052160

A method for treating a condition associated with metabolic syndrome or for treating adiposis dolorosa (ad) comprises applying peripheral blood from a patient or subject to an apheresis column loaded with a solid support comprising one or more binding reagents capable of specifically binding to a chemokine receptor, optionally the chemokine receptor ccr2, ccr1, ccr3, ccr4 or ccr5 immobilized directly ...
Compositions and methods for treating and preventing hyperlipidemia, fatty liver, atherosclerosis and other disorders associated ...
Vanderbilt University
February 22, 2018 - N°20180050083

The present invention relates to compositions and methods for treating diseases associated with dyslipidemia, including hypercholesterolemia, hypertriglyceridemia, steatohepatitis, atherosclerosis, obesity, hyperglycemia, metabolic syndrome, and related aspects of and conditions associated with metabolic syndrome. The compositions and methods disclosed herein are useful for regulating the lipid balance (lipid homeostasis) in a subject.
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