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Mass Spectrometry

Mass Spectrometry-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Methods for mass spectrometry of mixtures of protein or polypeptides using proton transfer reaction
Thermo Finnigan Llc
April 12, 2018 - N°20180102243

A method comprises: (1) making an extract of a biological sample; (2) repeatedly: (a) choosing a respective one of a plurality of pre-determined protein or polypeptide analyte compounds; (b) introducing a portion of the extract into an electrospray ionization source, thereby generating positive ions comprising a plurality of ion species; (c) isolating a plurality of subsets of the ion species comprising respective ...
Systems and methods for ambient surface cleaning and sampling with mass spectrometric analysis
Purdue Research Foundation
April 12, 2018 - N°20180102242

The invention generally relates to systems and methods for continuous or batch wise sampling of a surface for analysis of trace chemical constituents that may be present on the surface by mass spectrometry. Integration of time and place of the sampling and analysis processes allows real-time on-the-spot response to the analytical data and can take into account that material is ...
Reagents and methods for simultaneously detecting absolute concentrations of a plurality of elements in a ...
New York University
April 12, 2018 - N°20180102240

Disclosed herein are internal standard compositions, a plurality of calibration standards, and one or more kits for use with mass spectrometry, particularly for use with an inductively coupled plasma mass spectrometer capable of simultaneous detection of a large number of ionization products over a large range of masses. Methods of using these reagent materials for the simultaneously detection of absolute ...
Mass Spectrometry Patent Pack
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Mass Spectrometry Patent Applications
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  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
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Systems and methods for using variable mass selection window widths in tandem mass spectrometry
Dh Technologies Development Pte. Ltd.
April 05, 2018 - N°20180096830

Systems and methods are used to analyze a sample using variable mass selection window widths. A tandem mass spectrometer is instructed to perform at least two fragmentation scans of a sample with different mass selection window widths using a processor. The tandem mass spectrometer includes a mass analyzer that allows variable mass selection window widths. The selection of the different ...
Detection method for quaternary ammonium compound having y-carboxyl group
Kaohsiung Medical University
March 29, 2018 - N°20180088124

The invention discloses a detection method for a quaternary ammonium compound having a γ-carboxyl group. The quaternary ammonium compound converts to a fluorophore labeled-quaternary ammonium compound; and therefore can be easily detected by reverse-phase liquid chromatography, fluorescence spectrometry or mass spectrometry. The invention also discloses a diagnostic method for carnitine deficiency which can be used to evaluate whether ...
Multiple attribute monitoring methodologies for complex samples
Waters Technologies Corporation
March 29, 2018 - N°20180088094

The present disclosure relates generally to a method of multiple attribute monitoring for biological and other complex compounds using a chromatography-optical detector-mass spectrometry method. The mass spectrometry method can use a high resolution mass spectrometer. The methodology utilizes similar analytical techniques and instruments for both the characterization and the monitoring of biological and other complex compounds.
Mass Spectrometry Patent Pack
Download 279+ patent application PDFs
Mass Spectrometry Patent Applications
Download 279+ Mass Spectrometry-related PDFs
For professional research & prior art discovery
inventor
  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Accelerator mass spectrometry device for simultaneously measuring isotopes
China Institute Of Atomic Energy
March 22, 2018 - N°20180082828

The present invention provides an accelerator mass spectrometry device for simultaneously measuring isotopes. In one embodiment, the device comprises a sputtering negative ion source for generating negative ions; the sputtering negative ion source being connected to an accelerating tube for simultaneously accelerating a plurality of isotopic ions; an output end of the accelerating tube being connected to an isotope mass ...
Nanopatterned extracellular matrices enable cell-based assays with a mass spectrometric readout
Northwestern University
March 22, 2018 - N°20180080058

The present disclosure provides methods in which adherent cells are treated with small molecules, cultured, lysed, and then analyzed by mass spectrometry to measure the activities of endogenous enzymes. The implementation of this method relies on the use of surfaces that are nanopatterned with cell adhesion ligands to mediate cell attachment and a peptide that is a substrate for the ...
Method for examining a gas by mass spectrometry and mass spectrometer
Carl Zeiss Smt Gmbh
March 08, 2018 - N°20180068842

A method for examining a gas by mass spectrometry includes: ionizing the gas for producing ions; and storing, exciting and detecting at least some of the produced ions in an ft ion trap. Producing and storing the ions in the ft ion trap and/or exciting the ions prior to the detection of the ions in the ft ion trap ...
Apparatus for mass analysis of analytes by simultaneous positive and negative ionization
Meridion, Llc
March 08, 2018 - N°20180068841

Among other things, we describe methods and apparatus for the ionization of target molecular analytes of interest, e. G., for use in mass spectrometry. In some implementations, a thin molecular stream is emitted in either single or a split mode and encounters both an electron-impact ion source and trochoidal electron monochromator placed sequentially or coincidently. The first ion source emits ...
Ion transfer device for mass spectrometry
Agilent Technologies, Inc.
March 08, 2018 - N°20180068840

An ion transfer device for transferring ions from one chamber to another, reduced-pressure chamber includes an inlet section and a main capillary section. The inlet section has a lumen and the main capillary section has a bore communicating with the lumen. The inside diameter of the lumen is less than that of the bore. The inlet section may be removable ...
Molecular markers and methods for sample analysis via mass spectrometry
Board Of Regents, The University Of Texas System
March 08, 2018 - N°20180067097

Methods for detecting cancer cells, or aggressive cancers, by measuring levels of cardiolipin molecules are provided. Methods of treating identified cancers are likewise provided
Integrated mass spectrometry systems
908 Devices Inc.
March 01, 2018 - N°20180061623

The disclosure features mass spectrometry systems that include: an ion source; a module featuring an ion trap, an ion detector, and a module housing that at least partially surrounds the ion trap and the ion detector; and a vacuum pump featuring a housing having a recess dimensioned to receive the module, so that when the module is positioned within the ...
Mass Spectrometry Patent Pack
Download 279+ patent application PDFs
Mass Spectrometry Patent Applications
Download 279+ Mass Spectrometry-related PDFs
For professional research & prior art discovery
inventor
  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Cell population analysis
Micromass Uk Limited
March 01, 2018 - N°20180059126

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed comprising: (a) using a first device to generate smoke, aerosol or vapour from a target in vitro or ex vivo cell population; (b) mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and (...
Inlet instrumentation for ion analyser coupled to rapid evaporative ionisation mass spectrometry ("reims") device
Micromass Uk Limited
March 01, 2018 - N°20180059119

An apparatus is disclosed comprising a first device for generating aerosol, smoke or vapour from one or more regions of a target, an inlet conduit to an ion analyser or mass spectrometer, the inlet conduit having an inlet through which the aerosol, smoke or vapour passes, and a venturi pump arrangement arranged and adapted to direct the aerosol, smoke or ...
Method of preparing sample for analysis and analysis method
Shimadzu Corporation
March 01, 2018 - N°20180059094

In the method of preparing a sample for analysis, a reaction is performed that produces different modified product depending on the sialic acid linkage type when a sialic acid is bound to a sugar chain of an analyte. In this reaction, an analyte containing a sugar chain, an amine containing two or more carbon atoms, and a dehydration-condensation agent are ...
Method of analyzing compound including amine group by using boc compound
Korea Institute Of Science And Technology
March 01, 2018 - N°20180059075

Provided is an amine group-derivatized composition including a boc compound for liquid chromatography-mass spectrometry (lc-ms) analysis, and when the amine group-derivatized composition is used in analysis using reverse-phase lc-ms, it is possible to effectively analyze compounds including an amine group and an amino acid at a low cost in a short time.
Method for detecting monoclonal antibody using mass spectrometry
March 01, 2018 - N°20180059074

In the method, a porous body in which a monoclonal antibody is immobilized in pores and nanoparticles on which a protease is immobilized are brought into contact with each other in a liquid to perform selective proteolysis of the monoclonal antibody, and a resulting peptide fragment is detected using liquid chromatography-mass spectrometry (lc-ms), and a peptide having an amino acid ...
Spectrometric analysis of microbes
Micromass Uk Limited
March 01, 2018 - N°20180057852

A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and ...
Improved ionisation of gaseous samples
Micromass Uk Limited
February 22, 2018 - N°20180053644

A method of mass spectrometry or ion mobility spectrometry is disclosed comprising: providing an analyte; supplying a matrix compound to said analyte such that said analyte dissolves in said matrix; forming first droplets of the dissolved analyte; and colliding said first droplets with a collision surface. The use of matrix improves the analyte ion signal.
Assays for recombinant expression systems
Janssen Vaccines & Prevention B.v.
February 22, 2018 - N°20180052173

The invention is a method for assessing protein expression by recombinant expression systems. The method uses mass spectrometry to quantify protein expression. The method has particular application in potency testing of vaccine compositions.
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