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Mass Spectrometry

Mass Spectrometry-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Microscale mass spectrometry systems, devices and related methods
The University Of North Carolina At Chapel Hill
June 15, 2017 - N°20170170001

Mass spectrometry systems or assemblies therefore include an ionizer that includes at least one planar conductor, a mass analyzer with a planar electrode assembly, and a detector comprising at least one planar conductor. The ionizer, the mass analyzer and the detector are attached together in a compact stack assembly. The stack assembly has a perimeter that bounds an area that ...
Srm assays to chemotherapy targets
Expression Pathology, Inc.
June 15, 2017 - N°20170168057

Methods are provided for quantifying the ent1, ercc1, folr1, rrm1, tubb3, topo1, and/or topo2a proteins directly in biological samples that have been fixed in formalin by the method of selected reaction monitoring (srm)/multiple reaction monitoring (mrm) mass spectrometry. The biological samples are treated with formaldehyde containing agents/fixatives including formalin-fixed tissue/cells, formalin-fixed/paraffin embedded (ffpe) tissue/...
Srm/mrm assays
Expression Pathology, Inc.
June 15, 2017 - N°20170168055

Methods are provided for quantifying specific proteins directly in biological samples that have been fixed in formalin by the method of selected reaction monitoring (srm) mass spectrometry, or what can also be termed as multiple reaction monitoring (mrm) mass spectrometry. Such biological samples are chemically preserved and fixed and can be tissues and cells treated with formaldehyde containing agents/fixatives ...
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Mass Spectrometry Patent Applications
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  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
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Polyacrylic acid (salt), polyacrylic acid (salt)-based water-absorbing resin, and process for producing same
Nippon Shokubai Co., Ltd.
June 15, 2017 - N°20170166670

A polyacrylic acid (salt), or a polyacrylic acid (salt)-based water-absorbing resin, contains a tracer for detecting various troubles in the water-absorbing resin during the period from the production of the water-absorbing resin to the use and discard thereof by a consumer. The polyacrylic acid (salt)-based water-absorbing resin has a stable carbon isotope ratio, as determined by accelerator mass ...
Mass spectrometry device
Hitachi High-technologies Corporation
June 08, 2017 - N°20170162375

A mass spectrometry device that can perform highly robust, highly sensitive, and low-noise analysis and addresses the problems of preventing reductions in ion transfer efficiency and of suppressing the introduction of noise components from droplets, etc. An ion source generates ions, a vacuum chamber is evacuated by an evacuation means and for analyzing the mass of ions, and an ion ...
Methods for mass spectrometry of mixtures of protein or polypeptides using proton transfer reaction
Thermo Finnigan Llc
June 08, 2017 - N°20170162372

Applications of ion-ion reaction chemistry are disclosed in which proton transfer reactions (ptr) are used to (1) simplify complex mixture analysis of samples introduced into a mass spectrometer, and (2) improve resolution and sensitivity for the analysis of large proteins in excess of 50 kda by removing charge and reducing the collisional cross section.
Mass Spectrometry Patent Pack
Download 279+ patent application PDFs
Mass Spectrometry Patent Applications
Download 279+ Mass Spectrometry-related PDFs
For professional research & prior art discovery
inventor
  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Polyacrylic acid (salt), polyacrylic acid (salt)-based water-absorbing resin, and process for producing same
Nippon Shokubai Co., Ltd.
June 08, 2017 - N°20170158791

Disclosed are a polyacrylate (salt) and a polyacrylate (salt) water-absorbent resin containing a tracer which can be verified back to the manufacturing process of the water-absorbent resin when dealing with various problems with the water-absorbent resin which can occur from the manufacturing process of the water-resistant resin, during the use thereof by a consumer, up until the disposal thereof. The ...
Metabolomic prediction of congenital heart defect during pregnancy, newborn and pediatric stages
King's College Hospital Nhs Foundation Trust
June 08, 2017 - N°20170156627

Particular aspects of the invention are methods for assaying metabolite levels in samples from a patient during pregnancy using nuclear magnetic resonance and direct flow injection mass spectrometry. In various methods, the assayed metabolites may be acylcarnitine or one or more of c3-oh (hydroxypropionylcarnitine), c5-oh (c3dc), c10, c5:1-dc (glutaconylcarnitine), c14:1-oh (hydroxytetradecenoylcarnitine) and c14:2-oh. One ...
Mass spectrometry system and method for contaminant identification in semiconductor fabrication
Globalfoundries Inc.
June 01, 2017 - N°20170154763

A mass spectrometer system includes a chamber configured to receive a sample; a gas source coupled to the chamber for delivering a gas across the sample; and a desorption energy source configured to desorb a contaminant from a test area of the sample. The system may also include a mass spectrometer including a vacuum source, an ion source, a mass ...
Particle beam treatment
The University Court Of The University Of Glasgow
June 01, 2017 - N°20170154760

A method of treating a particle beam is disclosed, of interest in particular for mass spectrometry for 14c. A particle beam including positive ions is passed through a charge exchange cell containing a target gas. The target gas is electrically insulating at room temperature and pressure. At least some of the positive ions of the particle beam are converted to ...
Mass spectrometry imaging of benign melanocytic nevi and malignant melanomas
Yale University
June 01, 2017 - N°20170154759

A method of differentiating benign melanocytic nevi from malignant melanomas is disclosed. The method generally includes subjecting a skin lesion sample from a patient to mass spectrometry to obtain a mass spectrometry protein profile. This profile is compared to mass spectrometry protein profiles of reference samples, which include known normal, benign melanocytic nevi, and/or malignant melanomas. Classification of the ...
Data processing device and method for the evaluation of mass spectrometry data
Thermo Fisher Scientific (bremen) Gmbh
June 01, 2017 - N°20170154169

A data processing device comprises a processor unit adapted to process a plurality of initial data vectors provided by a chromatograph and/or a mass spectrometer, the processing being carried out in one, two or more processing steps producing items of processed data, and a storage unit adapted to save and retrieve initial data vectors and/or items of processed ...
Reduction of oxidated methionine peptides for mass spectrometry
California Institute Of Technology
June 01, 2017 - N°20170152541

A method for preparing a methionine-containing peptide or protein for analysis by mass spectrometry includes incubating the methionine-containing peptide or protein with a heterologous methionine sulfoxide reductase a (msra), msrb, or msrab enzyme resulting in the reduction of oxidized methionine-containing peptides or proteins.
Mass Spectrometry Patent Pack
Download 279+ patent application PDFs
Mass Spectrometry Patent Applications
Download 279+ Mass Spectrometry-related PDFs
For professional research & prior art discovery
inventor
  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Laser ablation cell
California Institute Of Technology
May 25, 2017 - N°20170148619

A laser ablation cell (1) comprises a flow channel (11) having an essentially constant cross-sectional area so as to ensure a strictly laminar flow in the flow channel. A sample chamber (21) is provided adjacent to a lateral opening (14) of the flow channel. A laser beam (41) enters the sample chamber (21) through a lateral window (16) and impinges on a surface (24) of a sample (23) to ...
System and method for matrix-coating samples for mass spectrometry
California Institute Of Technology
May 25, 2017 - N°20170148618

Disclosed herein are embodiments of a system and method for preparing matrix-coated samples for analysis using mass spectrometry. In particular disclosed embodiments, the system and methods of using the system utilize an electric field to enhance results obtained from mass spectrometric analysis of the matrix-coated samples. The methods disclosed herein can be used to prepare biological samples that have improved ...
Alysine monomethylated derivative and corresponding antibody and use thereof
California Institute Of Technology
May 25, 2017 - N°20170146550

Provided are artificially synthesized modified mono-methylated lysines and modified mono-methylated lysine derivatized polypeptides. Also provided is an antibody produced by using this modified mono-methylated lysine and modified monomethylated lysine derivatized polypeptide as an antigen, the antibody can be used in recognizing and enriching the modified polypeptide after the lysine mono-methylated polypeptide being derivatized in vitro. Also provided are a preparation ...
Isobaric mass labels
California Institute Of Technology
May 25, 2017 - N°20170146549

The present invention relates to a set of two or more mass labels, wherein each mass label comprises the formula: x-l-m-re wherein x is a reporter moiety having an exact mass, l is a bond cleavable by collision in a mass spectrometer, m is a mass modifier, and re is a) a reactive functionality for attaching the mass label to ...
Mass spectrometric quantitation
California Institute Of Technology
May 25, 2017 - N°20170146544

Provided is a method of assaying for an analyte, including combining a test sample having the analyte, with a calibration sample having at least two different aliquots of the analyte, each aliquot having a different known quantity of the analyte. The test sample and each aliquot are differentially labeled with one or more isobaric mass labels each with a mass ...
Addition of reactive species to icp source in a mass spectrometer
Thermo Fisher Scientific (bremen) Gmbh
May 18, 2017 - N°20170140914

Disclosed is a method of inductively coupled plasma mass spectrometry (icp-ms), comprising steps of introducing at least one sample comprising at least one sample species, and at least one reactive species, into an inductively coupled plasma source, such that at least one molecular adduct ion of the at least one reactive species and the at least one sample species is ...
Photo-dissociation of proteins and peptides in a mass spectrometer
Micromass Uk Limited
May 18, 2017 - N°20170140910

A method of mass spectrometry is disclosed comprising directing first photons from a laser onto ions located within a 2d or linear ion guide or ion trap. The frequency of the first photons is scanned and first photons and/or second photons emitted by the ions are detected. The ions are then mass analysed using a time of flight mass ...
Quantitative peptide analysis by mass spectrometry
Anderson Forschung Group Llc
May 18, 2017 - N°20170138955

A method for determining the concentration ratio in a sample of a target peptide to a reference peptide that is chemically identical with the target peptide, but labeled by isotopes, acquires mass spectra of the target and reference peptides. One of a plurality of families of superimposed bell-shaped curves which is a best fit to ion current peak groups of ...
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