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Mass Spectrometry

Mass Spectrometry-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Mass spectrometry analysis of biomolecules by multiple charge state selection using a concurrent precursor isolation ...
Thermo Finnigan Llc
December 07, 2017 - N°20170352529

A method is described for the analysis of biological polymers, for example, intact proteins or oligonucleotides, by mass spectrometry. This method produces sample ions from a sample containing biological polymers, and ion species are selected that correspond to different charge states of a biological polymer molecule. The ion species are concurrently isolated from the sample ions to generate precursor ions ...
Apparatus and method for static gas mass spectrometry
Thermo Fisher Scientific (bremen) Gmbh
December 07, 2017 - N°20170352528

A method of static gas mass spectrometry is provided. The method includes the steps of: introducing a sample gas comprising two or more isotopes to be analyzed into a static vacuum mass spectrometer at a time, t0; operating an electron impact ionization source of the mass spectrometer with a first electron energy below the ionization potential of the sample gas ...
Method for validating existence of urinary exosome, non-invasive method for identifying urothelial cancer, and method ...
China Medical University
December 07, 2017 - N°20170350902

The present disclosure relates to a method for validating an existence of a urinary exosome including steps as follows. A urine sample is obtained from a subject. The urine sample is performing a serially centrifugation step to obtain a third precipitate. The third precipitate is resuspended with an extraction solvent to obtain a third mixture, and the third mixture is ...
Mass Spectrometry Patent Pack
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Mass Spectrometry Patent Applications
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  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
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Determination of glycosaminoglycan levels by mass spectrometry
Shire Human Genetic Therapies, Inc.
December 07, 2017 - N°20170350900

Detecting glycosaminoglycans (gags) and/or determining the level of one or more glycosaminoglycans can be useful, e. G., in identifying or monitoring various medical conditions, the status of patients having various medical conditions, and/or the response to treatment of individuals having various medical conditions. The present invention provides methods for detecting glycosaminoglycans and/or determining the level of glycosaminoglycans ...
Analyzing a complex sample by ms/ms using isotopically-labeled standards
Thermo Finnigan Llc
November 30, 2017 - N°20170345632

A method and corresponding apparatus are disclosed for analysis of a peptide-containing sample. The sample is prepared by adding isotopically-labeled peptides corresponding to endogenous peptides of interest, and the prepared sample is analyzed by liquid chromatography-mass spectrometry (lcms). Detection in a high-resolution, accurate mass (hram) ms1 spectrum of a precursor ion matching an isotopically-labeled peptide triggers acquisition of an ms/...
Method for quantitative analysis of complex proteomic data
Thermo Finnigan Llc
November 30, 2017 - N°20170344700

This invention is a novel method for analysis of data that is produced by test equipment. The preferred embodiment is data produced by liquid chromatography tandem mass spectrometry (lc-ms/ms) equipment, using industry standard methods to generate the initial data from the test equipment. The invention is a method for processing of the data to promptly produce accurate, reliable, and ...
Mass Spectrometry Patent Pack
Download 279+ patent application PDFs
Mass Spectrometry Patent Applications
Download 279+ Mass Spectrometry-related PDFs
For professional research & prior art discovery
inventor
  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Analysis method and analysis device
Hitachi High-technologies Corporation
November 30, 2017 - N°20170343540

Provided is a high-accuracy analysis method utilizing an enzyme-lined immunoassay. The presence of an analyte 3 can be detected or the abundance of the analyte 3 can be analyzed by: bonding an antibody 5 that is capable of specifically bonding to the analyte 3 immobilized on a solid phase 1 and has an enzyme 7 bonded thereto; then decomposing an enzyme substrate 8, which can generate decomposition ...
Single cell analysis using secondary ion mass spectrometry
The Board Of Trustees Of The Leland Stanford Junior University
November 30, 2017 - N°20170343529

A method of analyzing a population of cells is disclosed. In certain embodiments, the method includes i) obtaining an array of cells on a substrate, wherein the cells are labeled with one or more mass tags and are separated from one another, ii) measuring, using secondary ion mass spectrometry (sims), the abundance of the one or more mass tags at ...
Methods of analyzing crude oil
Purdue Research Foundation
November 30, 2017 - N°20170343526

The invention generally relates to methods of analyzing crude oil. In certain embodiments, methods of the invention involve obtaining a crude oil sample, and subjecting the crude oil sample to mass spectrometry analysis. In certain embodiments, the method is performed without any sample pre-purification steps.
Systems and methods for sample comparison and classification
Thermo Finnigan Llc
November 23, 2017 - N°20170338089

A system includes a database server and a plurality of processing nodes. The plurality of processing nodes are configured to receive mass spectrometry data from a plurality of samples; align the mass spectrometry data to correct for changes in retention time to generate a reference alignment; cluster compounds across the plurality of samples; store the reference alignment and clustered compound ...
Methods and systems for assembly of protein sequences
Bioinformatics Solutions Inc.
November 23, 2017 - N°20170336419

Methods and systems for determining amino acid sequence of a polypeptide or protein from mass spectrometry data is provided, using a weighted de bruijn graph. Extracted and purified protein is cleaved into a mixture of peptide and then analyzed using mass spectrometry. A list of peptide sequences is derived from mass spectrometry fragment data by de novo sequencing, and amino ...
Methods for detecting hormones and other analytes
Sanis Biomedical, Llc
November 16, 2017 - N°20170328921

The present application relates to methods for determining the concentration of one or more hormones in a sample by liquid chromatography-tandem mass spectrometry (lc-ms/ms).
Systems and methods for discovery and analysis of markers
Sanis Biomedical, Llc
November 16, 2017 - N°20170328885

A business method for use in classifying patient samples. The method includes steps of collecting case samples representing a clinical phenotypic state and control samples representing patients without said clinical phenotypic state. Preferably the system uses a mass spectrometry platform system to identify patterns of polypeptides in said case samples and in the control samples without regard to the specific ...
Mass Spectrometry Patent Pack
Download 279+ patent application PDFs
Mass Spectrometry Patent Applications
Download 279+ Mass Spectrometry-related PDFs
For professional research & prior art discovery
inventor
  • 279+ full patent PDF documents of Mass Spectrometry-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Method for specific cleavage of c alpha-c bond and side chain of protein and peptide, ...
National University Of Corporation Hiroshima University
November 16, 2017 - N°20170327533

The present invention provides a method for specifically cleaving a cα-c bond of a peptide backbone and/or a side chain of a protein and a peptide, and a method for determining amino acid sequences of protein and peptide. A method for specifically cleaving a cα-c bond of a peptide backbone and/or a ...
Methods, apparatus, and system for mass spectrometry
National University Of Corporation Hiroshima University
November 02, 2017 - N°20170316928

A miniature, low cost mass spectrometer capable of unit resolution over a mass range of 10 to 50 amu. The mass spectrometer incorporates several features that enhance the performance of the design over comparable instruments. An efficient ion source enables relatively low power consumption without sacrificing measurement resolution. Variable geometry mechanical filters allow for variable resolution. An onboard ion pump removes the ...
Sampling interface for mass spectrometry systems and methods
National University Of Corporation Hiroshima University
November 02, 2017 - N°20170316926

Methods and systems for delivering a liquid sample to an ion source for the generation of ions and subsequent analysis by mass spectrometry are provided herein. In accordance with various aspects of the present teachings, ms-based systems and methods are provided in which a desorption solvent utilized in a sampling interface to desorb one or more analyte species from an ...
Gel electrophoresis chip
National University Of Corporation Hiroshima University
November 02, 2017 - N°20170315089

The present invention discloses a gel electrophoresis chip, comprising a first substrate, a first plurality of parallel gel strips formed on the first substrate, respectively extending along a first direction and having a certain width; and a second plurality of isolation segments formed on the first substrate, respectively located between adjacent gel strips and extending along a second direction different ...
Determination of ligninases activities by nano-structure initiator mass spectrometry
National University Of Corporation Hiroshima University
November 02, 2017 - N°20170314058

A method for rapid, high throughput screening of the activities of enzymes, especially ligninases and its enzyme cocktails, using nanostructure initiator mass spectrometry (nims) surfaces, substrates and methodology.
Mass spectrometry analysis of microorganisms in samples
Purdue Research Foundation
October 26, 2017 - N°20170309462

The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
Ion transfer tube with sheath gas flow
Smiths Detection Inc.
October 26, 2017 - N°20170309461

An ion transfer tube assembly, a mass spectrometry system, and a method for providing an ion stream to an ion detection device are described that include using an ion transfer tube that provides a coaxial sheath gas flow. In an implementation, an ion transfer tube assembly includes an ion transfer tube for delivering the ion stream, where a sheath gas ...
Effect-directed identification of targeted and non-targeted androgen disruptors
Nanjing University
October 26, 2017 - N°20170307589

Implementations herein relates to effect-directed identification of targeted and non-targeted androgen disruptors. The implementations include primary separation, androgenic activity testing, high throughput separation and preparation of toxicants, active component scanning based on high performance liquid chromatography-time of flight mass spectrometry, targeted screening of suspicious androgenic substances, non-target identification of androgenic compounds combining mass spectrum, chromatography and toxicity characteristics and toxicity ...
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