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Mammal

Mammal-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Cell identification method
Centre National De La Recherche Scientifique (cnrs)
December 07, 2017 - N°20170350889

The present invention relates to the use of a nucleic acid molecule encoding a first reporter gene, bordered by at least one first pair and one second pair of sequences targeting a site-specific recombinase in order to detect cells of a mammal infected with a virus responsible for an immunodeficiency.
Compositions and methods for diagnosing thyroid cancer
Diaxonhit
December 07, 2017 - N°20170349951

The present application relates to methods and compositions for detecting thyroid cancer in mammals, in particular in humans. The invention provides novel biomarkers which, in combination, allow effective, specific and sensitive detection of thyroid cancer, particularly to assist in the diagnosis of thyroid lesions in human subjects. The invention further relates to tools and/or kits (such as reagents, probes, ...
Production of differentiated enteroendocrine cells and insulin producing cells
The Brigham And Women's Hospital, Inc.
December 07, 2017 - N°20170349884

A population of enteroendocrine cells (eec) is obtained from a mammalian post-natal cell population, such as a population including post-natal stem cells, by treating the population with a plurality of small molecules that upregulate chga and promote differentiation of the cells to form the enteroendocrine cells. The upregulation of chga is such that the fraction of cells expressing cga in ...
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Novel hybrid galactoside inhibitor of galectins
Galecto Biotech Ab
December 07, 2017 - N°20170349622

The present invention relates to a compound of the general formula (1). The compound of formula (1) is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore the present invention concerns a method for treatment of a disorder relating to ...
Alpha-d-galactoside inhibitors of galectins
Galecto Biotech Ab
December 07, 2017 - N°20170349619

An embodiment of the present invention relates to a compound of the general formula. The compound of formula is suitable for use in a method for treating a disorder relating to the binding of a galectin, such as galectin-3 to a ligand in a mammal, such as a human. Furthermore an embodiment of the present invention concerns a method for ...
Graft scaffold for cartilage repair and process for making same
Eth Zurich
December 07, 2017 - N°20170348458

The present invention relates to a method of providing a graft scaffold for cartilage repair, particularly in a human patient. The method of the invention comprising the steps of providing particles and/or fibres; providing an aqueous solution of a gelling polysaccharide; providing mammalian cells; mixing said particles and/or fibres, said aqueous solution of a gelling polysaccharide and said ...
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Vaccination methods
Turnstone Limited Partnership
December 07, 2017 - N°20170348404

In one aspect, a method of treating cancer in a mammal is provided. The method comprises administering to the mammal an oncolytic vector that expresses a tumour antigen to which the mammal has a pre-existing immunity. In another aspect, a method of boosting immune response in a mammal having a pre-existing immunity to an antigen is provided comprising intravenous administration ...
Medicinal composition of extract of seed of emblica officinalis and method of preparing the same
Turnstone Limited Partnership
December 07, 2017 - N°20170348368

A composition having an extract of seed of emblica officinalis. Methods of preparing extract of seed of emblica officinalis. An amla seed blend composition having various ratios of extracts of seeds of emblica officinalis. Nutraceutical or pharmaceutical methods for decreasing the total cholesterol, decreasing triglyceride, decreasing blood glucose level, enhancing hdl-c levels, increasing the hdl-c level to total cholesterol ratio, ...
Compositions and methods for treating inflammatory bowel diseases (ibds) and other disorders
Crestovo Llc
December 07, 2017 - N°20170348360

The present disclosure is in the field of pharmaceutical compositions suitable for the treatment of diseases in mammals. This application provides novel compositions and methods for treating various disorders or conditions that are associated with a dysfunctional intestinal microbiota. In particular, this application provides compositions and methods that can treat or cure gastrointestinal (gi) disorders such as inflammatory bowel disease (...
Serine/threonine kinase inhibitors
Genentech, Inc.
December 07, 2017 - N°20170348310

Compounds of formula i or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of formula i or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian ...
Soothing composition for animals, comprising at least one fatty acid and nepetalactone
Virbac
December 07, 2017 - N°20170348267

The invention relates to novel soothing compositions for animals, particularly for cats. It specifically relates to soothing compositions for non-human mammals, comprising between 1% and 50% w/w of at least one fatty acid comprising between 5 and 22 carbon atoms and between 0. 01% and 5% w/w of nepetalactone, such that said at least one fatty acid and said nepetalactone are dissolved in a solvent. ...
Bakuchiol compositions for treatment of post inflammatory hyperpigmentation
Unigen, Inc.
December 07, 2017 - N°20170348250

Methods for treating excess pigmentation, including treatment of post inflammatory hyperpigmentation (pih), are disclosed. The disclosed methods comprise administration of a composition comprising bakuchiol substantially free of furanocoumarins to a mammal. Compositions comprising bakuchiol and methods for their preparation are also disclosed.
Method and composition for targeted delivery of therapeutic agents
Memorial Sloan-kettering Cancer Center
December 07, 2017 - N°20170348234

Functionalized single walled or multi-walled carbon nanotubes (f-cnts) can be delivered into mammals to targeted organs, such as the kidney and the liver. These f-cnts may be non-covalently linked or covalently linked to therapeutic agents. In particular, the application delivers carbon nanotube-therapeutic agent conjugates to a target organ, thereby preventing or reducing damages to the organ caused by other agents ...
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Calcium phosphate polymer composite and method
The University Of Connecticut
December 07, 2017 - N°20170348104

A bone-repair composite includes a core and a sheath. The core is a first primary unit including a combination of a first set of yarns coated with a calcium phosphate mineral layer. The first set of yarns being made from a first group of one or more polymers. The sheath is a second primary unit a combination of a second ...
Method, device, and system for shaving and shaping of a joint
The University Of Connecticut
December 07, 2017 - N°20170348011

Described herein are methods and devices useful for reaming and shaping the surfaces of a joint in a mammalian body. The reaming and shaping devices and methods are particularly useful in preparation of a joint for a minimally invasive joint replacement or resurfacing, though they may be used as part of any appropriate arthroplasty procedure.
Ship-towed hydrophone volumetric array system apparatus
The University Of Connecticut
November 30, 2017 - N°20170343687

This invention provides a system apparatus and method for ship-towed deployment of a non-linear volumetric array of hydrophones, allowing line-intersect or line-transect sampling of marine mammal populations through passive acoustic monitoring, enabling unambiguous real-time three-dimensional localization of single sounds received through a low-cost, modular, robust, stable, small, light, neutrally to slightly negatively buoyant volumetric array having low self-noise and low ...
Biomarkers for seizures
The Trustees Of The University Of Pennsylvania
November 30, 2017 - N°20170343565

The application relates to markers for seizures and epilepsy. Polypeptide expression panels or arrays are provided, comprising one or more probes capable of binding specific polypeptides in blood plasma or blood serum of a mammalian subject. Also provided are methods for detecting seizure, methods for predicting seizure, use of sicam-5 in the treatment of seizure, methods for assessing the effectiveness ...
Method for the determination of anti-drug antibodies against an effector function suppressed human or humanized ...
Hoffmann-la Roche Inc.
November 30, 2017 - N°20170343560

Herein is reported an anti-drug antibody immunoassay for the determination of the presence of an anti-drug antibody against an effector function suppressed human or humanized drug antibody in a sample comprising the incubation of a sample comprising mammalian blood serum with full length human fcgamma receptor i or an fc-region binding fragment thereof so that a complex between the anti-drug ...
Methods, devices, kits and compositions for detecting roundworm, whipworm and hookworm
Monsanto Company
November 30, 2017 - N°20170343544

Methods, devices, kits and compositions for detecting the presence or absence of one or more helminthic coproantigens in a sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of roundworm, whipworm and/or hookworm in a fecal sample from a mammal and may also be able ...
Hepatocyte based insulin gene therapy for diabetes
Wisconsin Alumni Research Foundation
November 30, 2017 - N°20170342441

A method and vectors for controlling blood glucose levels in a mammal are disclosed. In one embodiment, the method comprises the steps of: treating the hepatocyte cells of a patient with a first, second or third vector, wherein the first vector comprises a promoter enhancer, glucose inducible regulatory elements, a liver-specific promoter, a gene encoding human insulin with modified peptidase ...
Chloroplast expressing colostrum or milk polypeptides
The Regents Of The University Of California
November 30, 2017 - N°20170342434

Provided are chloroplasts engineered to recombinantly express mammalian colostrum and milk polypeptides photosynthetic organisms containing such chloroplasts, and compositions comprising such organisms and methods for producing such organisms. In certain embodiments, provided is a chloroplast comprising one or more polynucleotides encoding one or more mammalian milk or colostrum polypeptides selected from osteopontin, lactadherin, cathelicidin-1, lysozyme, lactoperoxidase, lingual antimicrobial peptide (lap), ...
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