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Mammal

Mammal-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Raav-guanylate cyclase compositions and methods for treating leber's congenital amaurosis-1 (lca1)
University Of Florida Research Foundation, Incorporated
April 12, 2018 - N°20180100165

Disclosed are viral vector compositions comprising polynucleotide sequences that express one or more biologically-active mammalian guanylate cyclase proteins. Also disclosed are methods for their use in preventing, treating, and/or ameliorating at least one or more symptoms of a disease, disorder, abnormal condition, or dysfunction resulting at least in part from a guanylate cyclase deficiency in vivo. In particular embodiments, ...
Protein kinase inhibitors
Princeton Drug Discovery Inc
April 12, 2018 - N°20180099961

The present invention concerns novel deuterated and non-deuterated cyclic chemical compounds and their corresponding salts thereof active on protein kinases in general, and in particular as inhibitors of protein kinases. Additionally, methods of treating mammals with protein kinase-mediated diseases or conditions by administering a therapeutically effective amount of the novel deuterated or non-deuterated cyclic chemical compound and their corresponding salts ...
Protein kinase inhibitors
Princeton Drug Discovery Inc
April 12, 2018 - N°20180099960

The present invention concerns novel deuterated and non-deuterated cyclic chemical compounds and their corresponding salts thereof active on protein kinases in general, and in particular as inhibitors of protein kinases. Additionally, methods of treating mammals with protein kinase-mediated diseases or conditions by administering a therapeutically effective amount of the novel deuterated or non-deuterated cyclic chemical compound and their corresponding salts ...
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Mammal Patent Applications
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Flanged self-closing microchannel array
The Florida International University Board Of Trustees
April 12, 2018 - N°20180099139

Devices and methods for implanting neural interface technology in mammals are provided. A device can include an array of self-closing channels; two flanges that flank the array of channels, the flanges can be used to open the self-closing channels; and a plurality of cuff electrodes disposed at a circumference of each self-closing channel, the plurality of cuff electrodes being optimally ...
Biocompatible containment member for bone augmentation surgery made of processed natural membrane from an animal ...
Osseous Technologies Of America
April 12, 2018 - N°20180099073

A surgically implantable containment member for maintaining a bone augmentation material in a desired location and/or configuration following implantation in a human or other mammalian patient, in which the containment member is made of a natural membrane, such as pericardium, isolated from an animal donor and processed to avoid inflammation or tissue rejection, and a method of bone augmentation ...
Vaccine compositions and methods of use thereof
University Of Miami
April 12, 2018 - N°20180099032

Nanoparticle-based vaccines, compositions, kits and methods are used for the effective delivery of one or more antigens in vivo for vaccination and antibody (e. G., monoclonal antibody) production, and for the effective delivery of peptides, proteins, sirna, rna or dna to papcs or mhc class ii positive cells (e. G. Tumor cells). Antigens may be, for example, dna that results ...
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Mammal Patent Applications
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  • 1087+ full patent PDF documents of Mammal-related inventions.
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Compositions and methods for treating chronic fatigue syndrome and related disorders
Crestovo Holdings Llc
April 12, 2018 - N°20180099013

The present disclosure is in the field of pharmaceutical compositions suitable for the treatment of diseases in mammals. The disclosure provides novel compositions comprising non-pathogenic fecal microbes for treating chronic fatigue syndrome and related diseases. The disclosure also provides methods for treating a subject with the compositions disclosed herein.
Compositions and methods for treating irritable bowel syndrome and related disorders
Crestovo Holdings Llc
April 12, 2018 - N°20180099011

The present disclosure is in the field of pharmaceutical compositions suitable for the treatment of diseases in mammals. The disclosure provides novel compositions comprising non-pathogenic fecal microbes for treating irritable bowel syndrome and related diseases. The disclosure also provides methods for treating a subject with the compositions disclosed herein.
Compositions and methods for treating multiple sclerosis and related disorders
Crestovo Holdings Llc
April 12, 2018 - N°20180099010

The present disclosure is in the field of pharmaceutical compositions suitable for the treatment of diseases in mammals. The disclosure provides novel compositions comprising non-pathogenic fecal microbes for treating multiple sclerosis and related diseases. The disclosure also provides methods for treating a subject with the compositions disclosed herein.
Magnesium picolinate compositions and methods of use
Jds Therapeutics, Llc
April 12, 2018 - N°20180098976

The present application relates to magnesium picolinate compositions and methods of use. The methods and compositions disclosed herein are particularly useful for providing bioavailable magnesium to mammals and treating or preventing symptoms of magnesium deficiency.
Inhibitors of abeta and synuclein aggregation
The Feinstein Institute For Medical Research
April 12, 2018 - N°20180098950

Provided are methods of inhibiting aggregation of amyloid-beta (aβ) or accumulation of aggregated aβ using certain guanylhydrazone compounds. Also provided are methods of treating or preventing an amyloid-related disease in a mammal, methods of treating a subject having alzheimer's disease, methods of treating a subject at risk for alzheimer's disease, methods of inhibiting aggregation or accumulation ...
Screening method, a kit, a method of treatment and a compound for use in a ...
Atrogi Ab
April 05, 2018 - N°20180095072

A method of screening for a candidate compound for the treatment of a condition involving dysregulation of metabolism in a mammal, said method comprising bringing a compound into contact with at least one population of cells, comprising cells that express mtor and akt and that are capable of activating mtorc2 and akt; determining mtorc2 activity and akt activity in cells ...
Method for recombinant protein production in mammalian cells
Universität Bielefeld
April 05, 2018 - N°20180094258

Some embodiments relate to methods for the recombinant expression of a protein of interest in a mammalian host cell, use of an shrna or an sirna directed against the galectin-1 gene for increasing the expression of a protein of interest in a mammalian host cell and kits comprising an shrna or an sirna and a cho cell.
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Mammal Patent Applications
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  • 1087+ full patent PDF documents of Mammal-related inventions.
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Compositions and methods for the induction and tuning of gene expression
Duke University
April 05, 2018 - N°20180094238

Disclosed herein are compositions of transcription activator-like effectors transcription factors and methods of using said compositions for inducing gene expression of mammalian genes.
Methods for the cryopreservation of mammalian cells
The General Hospital Corporation
April 05, 2018 - N°20180094232

Manufactured capillary tubes can include: a tubular member; and a coating applied partially covering the tubular member, the coating defining a window where the tubular member is free of the coating. Kits containing and methods related to the capillary tubes can be used for the cryopreservation of cells.
Microcarriers, matrices and scaffolds for culturing mammalian cells and methods of manufacture
Howard University
April 05, 2018 - N°20180094080

Microcarriers, matrices and scaffolds for growing mammalian cells are provided which include copolymer particles and matrices comprising of polysaccharide-polyamine copolymers. The copolymeric particles and matrices have a pore size of at least 50 microns and permit the mammalian cells to grow both on an exterior surface of the particles and matrices and within an interior of the particles and matrices. Methods ...
Anti-human papillomavirus 16 e6 t cell receptors
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv
April 05, 2018 - N°20180094041

Disclosed is a t cell receptor (tcr) having antigenic specificity for an hla-a2-restricted epitope of human papillomavirus (hpv) 16 e6, e629-38. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and populations of cells are also provided. Antibodies, or an antigen binding portion thereof, and pharmaceutical compositions relating to the tcrs of the ...
Inhibition of axl/gas6 signaling in the treatment of liver fibrosis
Aravive Biologics, Inc
April 05, 2018 - N°20180094034

Compositions and methods are provided for alleviating endometriosis, kidney disease, inflammatory disease and/or transplant rejection in a mammal by administering a therapeutic dose of a pharmaceutical composition that inhibits axl, mer or tyro3 protein activity, for example by competitive or non-competitive inhibition of the binding interaction between axl, mer or tyro3 and its ligand gas6.
Method of inhibiting apolipoprotein-e expression while increasing expression of at least one of ldl-receptor protein ...
Mayo Foundation For Medical Education And Research
April 05, 2018 - N°20180093960

This invention offers an effective method of decreasing expression of apolipoprotein e and increasing expression of at least one of either ldl-receptor protein or abca1 protein including selecting mammalian cells expressing apoe and at least one of either ldl-receptor protein or abca1 protein, contacting the mammalian cell with an effective amount of a compound having general formula (i) or general ...
Kit and method for topical delivery of benefits
Johnson & Johnson Consumer Inc.
April 05, 2018 - N°20180093106

A system for delivering energy to an isolated part of a mammalian body includes an electrically powered patch and a self-supporting adhesive film. The patch has a major surface and comprises a matrix of at least one flexible, biocompatible material which is capable of conforming to the isolated body part. The self-supporting adhesive film has a first non-tacky surface arranged ...
Method and apparatus for supplying energy to a medical device
April 05, 2018 - N°20180093100

An apparatus is disclosed, configured to control transmission of wireless energy supplied to an electrically operable medical device adapted to be implanted in a mammal patient. The apparatus comprises an external energy source adapted to be located outside the mammal patient and comprising an external control unit, wherein the external energy source is adapted to transmit wireless energy. Further, the ...
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