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Mammal

Mammal-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Use of soluble cd146 as a biomarker to select in vitro-fertilized embryo for implantation in ...
Assistance Publique Hopitaux De Marseille
June 14, 2018 - N°20180164323

The present invention relates to the field of human fertility treatment. The present invention more specifically relates to the identification of soluble cd146 (scd146) as a biomarker which, when measured in an embryo culture medium, can be used to determine whether the embryo can be selected for implantation in the uterus of a mammal or not.
Detection of allergens using surface-enhanced raman scattering
General Mills, Inc.
June 14, 2018 - N°20180164297

A technique can be used to detect and/or quantify allergens in foods. In some examples, the technique involves adding magnetic particles that carry antibodies and surface-enhanced raman scattering (sers) tags complexed with antibodies to the sample.
Methods and products for producing engineered mammalian cell lines with amplified transgenes
Precision Biosciences, Inc.
June 14, 2018 - N°20180163233

Methods of inserting genes into defined locations in the chromosomal dna of cultured mammalian cell lines which are subject to gene amplification are disclosed. In particular, sequences of interest (e.g., genes encoding biotherapeutic proteins) are inserted proximal to selectable genes in amplifiable loci, and the transformed cells are subjected to selection to induce co-amplification of the selectable gene and ...
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Antibodies against the rgm a protein and uses thereof
Abbvie Inc.
June 14, 2018 - N°20180162933

The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind and neutralize rgm a protein. Specifically, these antibodies have the ability to inhibit the binding of rgm a to its receptor and/or coreceptors.
Drug delivery and imaging chemical conjugate, formulations and methods of use thereof
Nanophagix Llc
June 14, 2018 - N°20180162869

The present invention relates to compounds, and methods of use thereof, capable of entering macrophages. The invention further relates to compounds capable of modulating (for example inhibiting) the activity of the mammalian target of rapamycin (mtor), treating mtor-associated diseases, in particular, but not limited to, related to mtor in macrophages.
Use of the irritating principal oleocanthal in olive oil, as well as structurally and functionally ...
The Trustees Of The University Of Pennsylvania
June 14, 2018 - N°20180162800

The invention provides methods of synthesizing the purified enantiomers of oleocanthal. The invention further provides methods of using oleocanthals in various formulations including, food additives; pharmaceuticals; cosmetics; animal repellants; and discovery tools for mammalian irritation receptor genes, gene products, alleles, splice variants, alternate transcripts and the like..
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Mammal Patent Applications
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  • 1087+ full patent PDF documents of Mammal-related inventions.
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Antidiabetic oral insulin biguanide combination
Emisphere Technologies, Inc.
June 14, 2018 - N°20180161400

Pharmaceutical dosage forms, comprising insulin, a delivery agent that facilitates insulin transport in a therapeutically effective amount to the bloodstream and a biguanide, such as metformin, are disclosed for oral administration to a patient for the treatment of diabetes. Also disclosed are methods for achieving improved glucose tolerance and glycemic control in a diabetic mammal without any statistically significant increase ...
Methods and related kits for treating and regenerating tooth pulp and periapical tissues in a ...
University Of Southern California
June 14, 2018 - N°20180161394

In one embodiment, a method of regenerating tooth pulp in a mammal is provided. The method comprises removing at least a portion the existing tooth pulp of a mammal and adding amelogenin protein to the existing tooth pulp of the mammal to regenerate tooth pulp in a mammal.
R-spondin agonist-mediated hair growth
Ulixa, Inc.
June 14, 2018 - N°20180161389

Cosmetic skin and hair care compositions for enhancing the growth and appearance of mammalian hair in an individual are provided, which compositions comprise a dose of an r-spondin agonist effective to promote anagen phase of the hair cycle.. .
Using autologous mesenchymal stem cells to treat multiple system atrophy
Mayo Foundation For Medical Education And Research
June 14, 2018 - N°20180161374

This document provides methods and materials for treating multiple system atrophy in a mammal. Specifically, the methods comprises intrathecally administering to the mammal a composition comprising autologous mesenchymal stem cells (e.g.
Estriol therapy for treatment of multiple sclerosis
The Regents Of The University Of California
June 14, 2018 - N°20180161346

The present invention discloses administering steroid hormones to mammals to treat autoimmune related diseases, including post-partum auto immune diseases. Most preferably the invention uses estrogens, estranges, estriol or estrogen receptor active agents to prevent or ameliorate clinical symptoms of these th1-mediated (cell-mediated) autoimmune diseases known to either have an initial onset following the birth of a child or which ...
Essential nutrients and related methods
Balchem Corporation
June 14, 2018 - N°20180161299

The present disclosure relates to pharmaceutical compositions for mammalian consumption containing essential fatty acids, protein, vitamins and choline, or combinations thereof, so constituted to optimize absorption and/or transport and/or efficiency of the co-ingredients of the composition. The pharmaceutical compositions are useful as supplements to provide nutrients to nutritionally deficient patients.
Stable personal care compositions containing a retinoid
The Procter & Gamble Company
June 14, 2018 - N°20180161259

Personal care compositions that include a stable o/w emulsion, a stable retinoid, an oil, a fatty alcohol, and an emulsifier and methods of using such compositions to regulate a condition of mammalian keratinous tissue. By combining the oil and retinoid at a particular ratio in the personal care composition, the stability of the retinoid can be improved..
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Mammal Patent Applications
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  • 1087+ full patent PDF documents of Mammal-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Optimizing diagnostics for galactofuranose containing antigens
The Johns Hopkins University
June 07, 2018 - N°20180156797

Disclosed herein are methods of detecting microbial infection in mammalian subjects comprising treatment of a sample and detection of galactofuranose (galf)-containing antigenic components utilizing monoclonal antibodies. The methods disclosed provide for pretreatment of biological samples, such as urine samples, to maximize detection of galf antigens and improvement of sensitivity of galf antigen detection assays.
Manganese supplementation for control of glycosylation in mammalian cell culture process
Biogen Ma Inc.
June 07, 2018 - N°20180155753

The present invention pertains to a cell culture medium comprising manganese as a media supplement, which was shown to control recombinant protein glycosylation and methods of using thereof. The present invention further pertains to a method of controlling or manipulating glycosylation of a recombinant protein of interest in a large scale cell culture..
Neural progenitor cell differentiation
Wake Forest University Health Sciences
June 07, 2018 - N°20180155684

Differentiation and stability of neural stem cells can be enhanced by in vitro or in vivo culturing with one or more extracellular matrix (ecm) compositions, such as collagen i, iv, laminin and/or a heparan sulfate proteoglycan. In one aspect of the invention, adult mammalian enteric neuronal progenitor cells can be induced to differentiate on various substrates derived from components ...
Low surface energy coatings for mammalian cell culture
Trustees Of Tufts College
June 07, 2018 - N°20180155666

A cultureware system is directed to maintaining viability of mammalian cells, and includes a disposable holding container having a cell receiver with a cell-receiving surface. The cell receiver consists of a cell-adhesion inducement material including a polystyrene material and a glass material.
Regulating il-4 and il-13 levels by blocking high affinity binding by il-3, il-5 and gm-csf ...
Newcastle Innovation Ltd.
June 07, 2018 - N°20180155435

A method of reducing il-4 and/or il-13 levels in the lung of a mammal with elevated levels thereof, includes the step of administering to the mammal an effective amount of a βc receptor blocker capable of blocking the binding of all three of il-3, il-5 and gm-csf to the βc common chain to thereby reduce ...
Cysteine-modifying substrate analogue inhibitors of ribose 5-phosphate isomerase for parasitic diseases, along with methods of ...
University Of South Carolina
June 07, 2018 - N°20180155373

Compounds are generally provided, along with pharmaceutical compositions including such compounds. Methods are also generally provided for inhibiting ribose 5-phosphate isomerase in a human, such as via administering to the human the pharmaceutical composition that includes such a compound.
Substituted heterocyclyl derivatives as cdk inhibitors
Aurigene Discovery Technologies Limited
June 07, 2018 - N°20180155293

The present invention provides substituted heterocyclyl derivatives of formula (i), which are therapeutically useful, particularly as selective transcriptional cdk inhibitors including cdk7, cdk9, cdk12, cdk13 and cdk18, more particularly transcriptional cdk7 inhibitors. These compounds are useful in the treatment and prevention of diseases and/or disorders associated with selective transcriptional cdks in a mammal.
Methods and apparatus for hygromorphic shape control
Massachusetts Institute Of Technology
June 07, 2018 - N°20180154627

A composite film includes a substrate that is not responsive to relative humidity, and also one or more layers of hygromorphic material. The hygromorphic material expands in response to an increase in relative humidity and contracts in response to a decrease in relative humidity.
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