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Malignant Cells patents
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|| List of recent Malignant Cells-related patents
|System for detecting, actively targeting and selectively treating malignant cells in human body by non-invasive procedure|
The embodiments herein provide a system and method for detecting, actively targeting and selectively treating the biological targets in a human body by a non-invasive procedure. The system comprises an electromagnetic inductor supported at a predetermined height and rotated to generate a high frequency magnetic field.
|Diagnosing cancer using genomic sequencing|
Methods, systems, and apparatus determine whether a first chromosomal region exhibits a deletion or an amplification associated with cancer in a sample from a subject (e.g., where the sample includes a mixture of cell-free dna from tumor cells and non-malignant cells. Nucleic acid molecules of the biological sample are sequenced.
|Diagnostic tests using gene expression ratios|
The invention provides methods for diagnosing biological states or conditions based on ratios of gene expression data from cell or tissue samples, such as cancer cell or tissue samples. The invention also provides sets of genes that are expressed differentially in normal and cancer lung cells and tissues.
|Use of tri-substituted glycerol compounds for the treatment of hematological malignancies|
The present invention relates to the use of a tri-substituted glycerol compound for the manufacture of a medicament for the treatment of hematological malignancies. The invention also refers to a kit-of-parts comprising such a medicament.
|Novel n- and c- terminal substituted antagonistic analogs of gh-rh|
There is provided a novel series of synthetic analogs of hgh-rh(1-29)nh2 (seq id no: 96) and hgh-rh(1-30)nh2. Of particular interest are those carrying phac, n-me-aib, dca, ac-ada, fer, ac-amc, me-nh-sub, phac-ada, ac-ada-d-phe, ac-ada-phe, dca-ada, dca-amc, nac-ada, ada-ada, or ch3—(ch2)10—co-ada, at the n-terminus and β-ala, amc, apa, ada, ae2a, ae4p, ε-lys(α-nh2), agm, lys(oct) or ahx, at the c-terminus.
|Targeting of cyp1b1 in the treatment of head and neck cancer and lung cancer|
Methods for inhibiting the motility or proliferation of premalignant and malignant cells are provided. Methods for treating a malignancy of the head and neck and for treating a malignancy of the lung are also provided..
|Oncolytic measles virus|
The present invention pertains to a pharmaceutical composition comprising a recombinant measles virus encoding a suicide gene for use in the treatment of malignant cells with primary or secondary resistances against an oncolytic measles virus without suicide gene activity. Further, the present invention pertains to a recombinant measles virus based on measles vaccine strain schwarz encoding a suicide gene, which comprises a fusion of a cytosine deaminase, particularly yeast cytosine deaminase, and a uracil phosphoribosyltransferase, particularly yeast uracil phosphoribosyltransferase, to a method and a kit for preparing the recombinant measles virus as claimed herein..
|Methods for screening compounds for capability to inhibit premalignant squamous epithelial cell progression to a malignant state|
Methods for screening compounds for their capability to inhibit cyp1b1-mediated proliferation and motility of and/or to reverse estrogen-induced reduction in apoptosis of premalignant or malignant cells are provided. Kits for practicing the screening methods are also provided..
|Methods and compositions for treatment of hematologic cancers|
The present invention relates to oncolytic picornaviruses and methods and compositions for treating subjects having hematologic cancers. These include methods and compositions for treatment of myeloma, using disclosed picornavirus such as coxsackievirus, in methods of direct or indirect administration to subjects and ex vivo purging of malignant cells within auto grafts prior to transplantation..
|Methods of generating oligodendrocytes and cell populations comprising same|
A method of generating a population of cells useful for treating a brain disorder in a subject is disclosed. The method comprises contacting mesenchymal stem cells (mscs) with at least one exogenous mirna having a nucleic acid sequence at least 90% identical to a sequence selected from the group consisting of seq id nos: 15-19 and 27-35, thereby generating the population of cells and/or generating neurotrophic factors that may provide important signals to damaged tissues or locally residing stem cells.
Mammography-apparatus for detecting malignant cells in a breast comprising an x-ray source and an x-ray detector that cooperates with the x-ray source for providing an x-ray image of said breast, and further comprising a paddle for flattening the breast by pressing it against said x-ray detector, wherein at least one sensor is applied for measuring a parameter that is used for determining the pressure at which the paddle compresses the breast, and wherein a control system is provided which controls the actuation of the paddle depending on the pressure that is applied to the breast, wherein there is a contact area measuring unit for measuring the contact area between the breast and the paddle.. .
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Malignant Cells topics: Malignant Cells, Malignant Cell, Proliferation, Premalignant, Recombinant, Stem Cells, Endogenous, Malignancy, Proliferative Disorder, Antagonist, Amino Acid, Growth Hormone, Proliferative, Amino Acids, Lung Cancer
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