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|| List of recent Lycopene-related patents
|Cells and methods for producing lutein|
Provided herein are recombinant cells (e.g., recombinant bacteria or plant, insect, mammalian, and yeast cells) containing a nucleic acid encoding a cyp97a protein or a nucleic acid encoding a cyp97b protein; a nucleic acid encoding a cyp97c protein; a nucleic acid encoding a geranylgeranyl pyrophosphate synthase protein; a nucleic acid encoding a phytoene synthase protein; a nucleic acid encoding a phytoene desaturase protein; a nucleic acid encoding a lycopene β-cyclase protein; and a nucleic acid encoding a lycopene ε-cyclase protein. Also provided are methods of producing lutein that include culturing these recombinant cells (e.g., recombinant bacteria and yeast cells), and methods of generating these recombinant cells (e.g., recombinant bacteria and yeast cells).
The Research Foundation Of The City University Of New York
|Efficient process for the preparation of lycopene containing oleoresin and lycopene crystals for human consumption|
The present invention provides a process for the preparation of lycopene containing oleoresin and lycopene crystals for human consumption. The present invention provides an efficient process for the preparation of lycopene crystals from lycopene containing oleoresin with at least 85% by weight lycopene, containing at least 90% by weight trans-lycopene and trace amounts of cis-lycopene and other carotenoids.
Omniactive Health Technologies Limited
|Apparatus for optical analysis of an associated tissue|
The present invention relates to an apparatus 100 and, a method and a computer program for determining a first parameter indicative of a concentration of lycopene. In particular, the invention relates to an apparatus 100 comprising a spectrometer 02, which spectrometer comprises a light source 104 and a detector 106, 108 arranged to measure an optical spectrum via an interventional device 112.
Koninklijke Philips N.v.
|Preparation 3,7,11- trimethyldodec -2,4,6,10-tetraene-1-yl-phosphonic salt|
Provided in the present invention is a preparation method for a phosphonic salt, comprising the step of: reacting 3,7,11-trimethyldodec-1,4,6,10-tetraene-3-ol with triarylphosphine and an acid in an alcohol solvent at 50-100° c. To form the phosphonic salt, wherein the acid is a sulfamic acid or methanesulfonic acid, and the alcohol solvent is a straight chain monohydric alcohol containing 1-5 carbon atoms.
Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory
|Preparation lycopene intermediate 3-methyl-4,4-dialkoxy-1-butaldehyde|
Disclosed is a preparation method of the lycopene intermediate 3-methyl-4,4-dialkoxy-1-butaldehyde. The preparation method comprises the following steps: (1) reacting 2-methyl-3,3-dialkoxy-1-halopropane with magnesium powder in the solvent of anhydrous tetrahydrofuran at a temperature of 45˜65° c.
|Formulations of lycopene in combination with bisphosphonates bone resorption inhibitors|
The present invention provides a pharmaceutical formulation suitable for filling softgel capsules comprising: (a) from about 1% to about 90% by weight of a bisphosphonic acid or a pharmaceutically acceptable salt; (b) from 1% to about 99% by weight of lycopene and (c) from about 40% to about 80% by weight of a liquid carrier comprising 50% to 80% by weight polyethylene glycol; 5% to 15% by weight of glycerin; and 5% to 20% by weight water. The invention also describes a method for preparing alendronate or its pharmaceutical acceptable salts in encapsulated therapeutic dosage form in combination with lycopene..
|Process for extracting lycopene|
A process for extracting lycopene, comprising the following steps: pressing and dehydrating tomato pomace which is the by-products of tomato processing production, then drying it to control the water content in the range from 10% to 20%; crushing the dried tomato pomace, and separating tomato skins and tomato seeds by air blast process, granulating the separated tomato skins and extracting them, then purifying by removing impurity from the extracted lycopene with active carbon. The process uses the by-products of tomato production as raw material, thus increasing the utilization ratio of tomatoes; the way of separating the seeds and skins after dehydrating and drying can save water and reduce the discharge of pollutant; the addition of antioxidant in the process of drying avoids the impact of high temperature on lycopene; extracting after granulating the tomato skins significantly increases the extracting efficiency; treating the extracting solution with active carbon effectively can remove the pesticide residues, impurities, odor etc., and thus increase the quality of lycopene..
|Volatile distillate by-product of mint oil that promotes absorption and/or bioavailability of compounds of bio-medical and nutritional interest|
Disclosed is an adjuvant for improving the bioavailability of bioactive compositions. The adjuvant is prepared from a byproduct of mint flavor production.
|Hybrid variety h1176 with high lycopene|
Hybrid tomato variety ‘h1176’ is described. The ‘h1176’ tomato variety is a ground-culture hybrid tomato variety suitable for machine harvest and has high levels of lycopene..
|Intermediate of lycopene and preparation intermediate|
The present invention relates to 2,6,10-trimethyl-3,5,9-undecatrienyl-1-aldehyde represented by formula (3), and a method for preparing this intermediate. The process route of the present invention is simple, the starting materials are available easily, and the cost is low..
Intermediate of lycopene and preparation intermediate thereof
The present invention relates to an intermediate (12) of lycopene of 2,6,10-trimethyl-1,1-dialkoxyl-3,5,9-undecantriene of formula, (12) and its intermediate of 4-methyl-5,5-dialkoxyl-1-pentenyl-1-phosphonic acid dialkyl ester of formula (10), and their preparation methods. The process route is simple, the starting materials are available easily, the cost is low, and it is valuable in industry..
Stable and bioavailable lycopene formulations and associate methods
Stable and bioavailable formulations and methods for lycopene extraction are disclosed and described. In particular, methods to extract plant lycopene without the use of organic (chemical) solvents, to produce a water soluble food ingredient and colorantant, which are stabilized by natural, antioxidants (vit e, vit c, beta-carotene).
Carotenoid particles and uses thereof
This invention relates to the incorporation of bioactive cargo molecules into particles with carotenoids, such as lycopene. The incorporation of a cargo molecule into a carotenoid particle may for example increase the bioavailability of the cargo molecule in the bloodstream compared to other delivery systems.
Skin anti-oxidant enhancing formulation and associated method
The present invention describes novel applications of an oil formulation rich in carotenoids and poly-unsaturated fatty acids (pufa) for skin care, lip care and cosmetic use. The formulation contains natural oil extract of momordica cochinchinensis spreng also known as gac, spiny melon, redmelon™.
Natural lycopene concentrate and production thereof
Natural lycopene concentrate obtained from a plant structure after alkalinization, solid-liquid separation, acidification and a second solid-liquid separation. The concentrate obtained is highly bioavailable and water-soluble at room temperature..
Combined absorption-reflection based instrument and technique to measure antioxidants (including carotenoids) in human tissue
A combined absorption-reflection based instrument and methods are introduced here to measure antioxidant carotenoids and similar compounds such as: beta-carotene, lycopene and lutein, along with others in living human tissue (e.g. Skin).
Treating male infertility secondary to sperm oxidative stress
A profertility composition for administration to infertile men with sperm oxidative stress is disclosed. The composition comprises a unique combination of a pharmaceutically acceptable vitamin e, vitamin c, selenium, zinc, folic acid, lycopene and at least one carnitine source..
Tomato-derived thickening agent
The present invention provides a tomato-derived thickening agent, said agent being characterized in that, on a dry n weight basis, it contains: 0.1-3 wt. % of lycopene; 14-34 wt.
High lycopene content tomato plants and markers for use in breeding for same
Solanum pimpinellifolium plants which are exceptionally high in fruit lycopene content (˜300-390 μg lycopene/g fresh fruit) are disclosed herein, which may be used in plant breeding to make the tomato plants of the present invention. The invention also discloses genetic markers, which are associated with the trait which may be used in marker-assisted selection for development of plants, lines, or varieties with the trait..
Process for production of high purity beta-carotene and lycopene crystals from fungal biomass
The present invention relates to a simple and economic method of extracting a crystalline carotenoid compound, such as beta-carotene, lycopene, with a purity of at least 99%. The present invention further describes a process to prepare such a highly pure crystalline carotenoid compound from microbial biomass, using an anti-purity compound removal process followed by a mono-solvent extraction method.
1-methoxyl-2, 6, 10-trimethyl-1, 3, 5, 9-undec-tetraene, and preparation method and uses thereof
The invention discloses an intermediate 1-methoxyl-2,6,10-trimethyl-1,3,5,9-undec-tetraene, and a preparation method and uses thereof. In the synthesis method for the current lycopene intermediate 2-pos double bond c-14 aldehyde (2,6,10-trimethyl-2,5,9-undecatriene-1-aldehyde), expensive methyl iodide, polluting dimethyl sulphide and dangerous strong base are needed, so that the method is hardly applied to industrial production.
Nutritional supplement for use under physiologically stressful conditions
In one embodiment of the present invention, a pharmaceutically-acceptable single-dosage formulation consists essentially of about 500 mg of vitamin c; about 400 ius of vitamin d3; about 125 ius of vitamin e; about 25 mg of vitamin b1; about 3.4 mg of vitamin b2; about 35 mg of niacin; about 35 mg of vitamin b6; about 1.25 mg of folic acid; about 70 mcg of vitamin b12; about 5 mg of pantothenic acid; about 75 mcg of biotin; about 35 mg of magnesium; about 35 mg of zinc; about 1 mg of copper; about 125 mcg of selenium; about 150 mcg of chromium; about 10 mg of alpha lipoic acid; about 35 mg of co-enzyme q-10; about 400 mcg of lutein; about 125 mcg of lycopene; and at least one or more excipients.. .
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Lycopene topics: Folic Acid, Carotenoids, Carotenoid, Vitamin B1, Vitamin B2, Vitamin B6, Pantothenic Acid, Nutritional Supplement, Vitamin B12, Phosphonate, Antioxidants, Antioxidant, Infertility, Male Infertility, Oxidative Stress
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