Lms

Lms-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).

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Oral films
Dinect Sarl
October 20, 2016 - N°20160303038

The invention relates to an oral film made from a copolymer of polyvinyl alcohol and polyethylene glycol and at least one gum. The oral films may further contain a medicated active and a non-medicated component. The film upon application, depending upon the quantity of gum and other additives may quickly disintegrate releasing its contents in the mouth or stay adhered ...
Antigen-binding proteins specific for hla-a2-restricted wilms tumor 1 peptide
Memorial Sloan-kettering Cancer Center
June 02, 2016 - N°20160152725

Antigen-binding proteins specific for hla-a2-restricted wilms tumor 1 peptide are disclosed. The antigen-binding proteins encompass antibodies in a variety of forms, including full-length antibodies, substantially intact antibodies, fab fragments, f(ab′)2 fragments, and single chain fv (scfv) fragments, as well as chimeric antigen receptors. Fusion proteins, such as scfv fusions with immunoglobulin or t-cell receptor domains, incorporating the antigen-binding ...
T cell immunotherapy specific for wt-1
Fred Hutchinson Cancer Research Center
March 24, 2016 - N°20160083449

The present disclosure provides high affinity and enhanced affinity t cell receptors specific for human wilms tumor protein 1 (wt-1) epitopes for use in treating diseases or disorders, such as cancer cells that overexpress wt-1.
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Organic compositions to treat beta-catenin-related diseases
Fred Hutchinson Cancer Research Center
October 15, 2015 - N°20150291954

The present disclosure relates to rnai agents useful in methods of treating beta-catenin-related diseases such as adenomatous polyposis of the colon, colorectal cancer, basal cell carcinoma, breast cancer, kidney cancer, wilms tumors, medulloblastoma, ovarian cancer, adrenocortical tumors, gastric cancer, liver cancer, melanoma, pancreatic cancers, prostate cancer, renal cancer, ectopic teeth and taste papillae, skin cancer, pilomatrixoma, anaplastic thyroid carcinoma, and ...
Disintegrable oral films
Novartis Ag
April 23, 2015 - N°20150111928

A water soluble film that is disintegrable in the oral cavity to deliver an active agent is provided. The disintegrable film includes at least one water soluble polymer and an active agent. Also provided are methods for preparing the disintegrable oral film and for using the disintegrable film to administer an effective dosage of an active agent into the oral ...
Packaging structure for biomedical films
Altergon Sa
January 22, 2015 - N°20150021222

A multilayer structure for the packaging of biomedical films, in particular oral films, is described, said multilayer structure comprising cold-adhesive laminates and at least partly non-adhesive supporting layers which are organized in a specific stratified structure. The film packaged therein is effectively isolated from the external environment and protected from accidental mechanical stresses; the packaging process is low-cost and particularly ...
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Cell for use in immunotherapy which contains modified nucleic acid construct encoding wilms tumor gene ...
Altergon Sa
June 26, 2014 - N°20140179004

A cell of the present invention contains a nucleic acid construct encoding a wt1 gene product or a fragment of the wt1 gene product. The nucleic acid construct contains (i) a region encoding a desired fragment of the wt1 gene product and (ii) only aug as a functional start codon. The present invention can provide a cell into which the ...
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