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Liver Disease

Liver Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Energy malnutrition evaluation for liver disease test subject
Otsuka Pharmaceutical Co., Ltd.
July 13, 2017 - N°20170199172

A method for measuring energy malnutrition in a liver disease test subject, a method for determining whether a liver disease test subject is in an energy malnutrition state, a method for determining the necessity of nutrition therapy for a liver disease test subject having energy malnutrition, a composition usable in these methods, and the like are provided. The method for ...
Prevention and treatment of non-alcoholic fatty liver disease
Ohio University
July 13, 2017 - N°20170196845

Methods for preventing, treating, and/or reducing the risk of developing non-alcoholic fatty liver disease in a subject in need thereof and pharmaceutical compositions for the prevention or treatment of non-alcoholic fatty liver disease. Methods for inhibiting excessive accumulation of fat in liver tissue. The methods include administering to the subject or contacting the liver tissue with a therapeutically effective ...
Treatment and prevention of liver disease associated with parenteral nutrition (pn)
Children's Medical Center Corporation
July 06, 2017 - N°20170189365

The present invention is based on the discovery that parenteral nutrition (pn) induced liver disease, e. G. Fatty liver disease, can be prevented and even reversed by administration of primarily omega-3-fatty acid with pn rather than the administration of the standard intravenous lipid emulsions that contain primarily plant derived omega-6 fatty acid. Thus, the present invention provides a method ...
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Breath test for assessing liver disease
Exalenz Bioscience Ltd.
June 29, 2017 - N°20170181686

There is provided herein a method and a device for measuring, using one or more breath sensors, a metabolic product of a fatty acid, a salt or a derivative thereof, in the subject's breath after administering to the subject an isotope labeled fatty acid, a salt or a derivative thereof, obtaining the subject's level of insulin, glucose, glucagon or a ...
Methods for assessing liver pathologies
The Chinese University Of Hong Kong
June 22, 2017 - N°20170175195

The present invention provides a new method for detecting or monitoring a liver disease in a subject that has no indication of any liver pathologies, by measuring the amount of concentration of albumin mrna in an acellular blood sample from the subject, and then comparing the amount or concentration of albumin mrna with a standard control.
Apoptosis signal-regulating kinase inhibitors
The Chinese University Of Hong Kong
June 22, 2017 - N°20170173031

Wherein variables are as defined above. The compounds have apoptosis signal-regulating kinase (“ask1”) inhibitory activity, and are thus useful in the treatment of ask1-mediated conditions, including autoimmune disorders, inflammatory diseases, cardiovascular diseases, diabetes, diabetic nephropathy, cardio-renal diseases, including kidney disease, fibrotic diseases, respiratory diseases, copd, idiopathic pulmonary fibrosis, acute lung injury, acute and chronic liver ...
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Liver Disease Patent Applications
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inventor
  • 100+ full patent PDF documents of Liver Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Treating liver diseases
Mayo Foundation For Medical Education And Research
June 08, 2017 - N°20170157205

This document provides methods and materials related to treating liver conditions. For example, the methods and materials relating to the use of camp inhibitors to treat liver conditions are provided.
Methods and compositions for diagnosis of inflammatory liver disease
Medizinische Hochschule Hannover
June 01, 2017 - N°20170153251

The present disclosure provides methods and compositions that find use in facilitating a diagnosis of inflammatory liver disease in a subject. The methods and compositions generally involve detection of eotaxin-3 (e3) levels, either alone or with levels of eotaxin-1 (e1), and optionally, with levels of ccl22 and, further optionally, with levels of il15. These levels can be used to facilitate ...
Inhibitors of the farnesoid x receptor and uses in medicine
The Penn State Research Foundation
June 01, 2017 - N°20170152283

Disclosed are inhibitors of the farnesoid x receptor, for example of formula (i), wherein r1, r2, r4, x, y, z, m, and n are as defined herein, which are useful in treating or preventing obesity, type 2 diabetes/insulin resistance and non-alcoholic fatty liver disease in a mammal in need thereof. Also disclosed is a composition comprising a pharmaceutically suitable carrier ...
A novel pharmaceutical composition of sofosbuvir and ribavirin
Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi
June 01, 2017 - N°20170151272

This invention is a novel pharmaceutical composition comprising sofosbuvir and ribavirin as active agents with at least one pharmaceutically acceptable excipient, wherein at least one of the active agents is in the form of controlled release, for use in the treatment of hepatitis c virus infections, chronic hepatitis c, hepatocellular carcinoma or patients with end-stage liver disease awaiting liver transplantation.
Calcitonin mimetics for treating diseases and disorders
Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi
May 25, 2017 - N°20170143800

Calcitonin mimetic peptides having an amino acid sequence in accordance with seq id no:8 or seq id no:53, each of which may be carboxylated at its n-terminal or otherwise modified to reduce the positive charge of the first amino acid and independently of that may be amidated at its c-terminal, and in each of which the 1 and 7 position cysteine residues ...
Orally administered adsorbent, therapeutic agent for renal disease, and therapeutic agent for liver disease
Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi
May 25, 2017 - N°20170143763

An object of the present invention is to provide an orally administered adsorbent capable of adsorbing large quantities of tryptophan or indoxyl sulfate in the presence of bile acid. Accordingly, the above object can be solved by an orally administered adsorbent characterized by containing surface-modified spherical activated carbon having bulk density from 0. 30 g/ml to 0. 46 g/ml, a specific surface ...
Apremilast for the treatment of a liver disease or a liver function abnormality
Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi
May 25, 2017 - N°20170143671

Methods of treating, managing or preventing liver disease are disclosed. Specific methods encompass the administration of apremilast, alone or in combination with additional active agents or treatment regimens.
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Liver Disease Patent Applications
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inventor
  • 100+ full patent PDF documents of Liver Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Method for diagnosing the risk of preneoplastic and neoplastic liver disease in subjects affected by ...
Universita' Degli Studi Della Basilicata
May 18, 2017 - N°20170138949

The invention herein described relates to an early and specific diagnosis method based on the use of the peptide fragment 75-99 of the urg7 protein. This peptide is used as an antigen to determine the presence of anti-urg7 antibodies in the sera of carrier subjects of the hepatitis virus, of hepatitis b in particular.
Pharmaceutical compositions of berberine with epa and dha, and methods thereof
Shenzhen Hightide Biopharmaceutical, Ltd.
May 18, 2017 - N°20170135995

The invention provides various novel compositions of berberine in combination with pharmacologically active epa and dha, and related methods of their use in treating various diseases or disorders. The pharmaceutical compositions of the invention are useful in treating and/or preventing various diseases or disorders, including metabolic diseases or disorders such as dyslipidemia, hyperglycemia, hypertriglyceridemia, hyperlipidemia, diabetic dyslipidemia, diabetic hyperlipidemia, ...
Formulations of l-ornithine phenylacetate
Ocera Therapeutics, Inc.
May 18, 2017 - N°20170135973

Some embodiments of the present application are directed to oral formulations of l-ornithine phenylacetate and methods of using the same. These oral formulations offer alternative administration route than the standard intravenous administration of l-ornithine phenylacetate for treating hyperammonemia in patients having various acute and chronic liver diseases and disorders, for example, acute liver failure, liver cirrhosis, liver decompensation, portal hypertension, ...
Modified release pharmaceutical compositions of sofosbuvir and ribavirin
Sanovel Ilac Sanayi Ve Ticaret A.s.
May 11, 2017 - N°20170128482

This invention is a novel modified release pharmaceutical composition comprising sofosbuvir and ribavirin and at least one pharmaceutically acceptable excipient for use in the treatment of hepatitis c virus infections, chronic hepatitis c (chc), hepatocellular carcinoma or patients with end-stage liver disease awaiting liver transplantation.
Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
Genfit
May 11, 2017 - N°20170128399

The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of general formula (i) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, ...
7-hydroxy cannabidiol (7-oh-cbd) for use in the treatment of non-alcoholic fatty liver disease (nafld)
Gw Pharma Limited
May 11, 2017 - N°20170128385

The liver plays a key role in regulating total body energy homeostasis and its ability to do so is greatly affected by the occurrence of pathological conditions such as hepatosteatosis or non-alcoholic fatty liver disease (nafld), which contributes to hepatic insulin resistance and potentially end-stage liver disease-related mortality. Triglyceride accumulation in hepatocytes of steatotic livers results from the incorporation of ...
Engineered polypeptides having enhanced duration of action
Astrazeneca Pharmaceuticals Lp
April 27, 2017 - N°20170114114

Compounds are provided having inter alia good duration of action, high potency and/or convenient dosing regimens including oral administration. The compounds are engineered polypeptides which incorporate an albumin binding domain in combination with one or more biologically active polypeptides. Also provided are pharmaceutical compositions and methods of treatment for diseases and disorders including obesity and overweight, diabetes, dyslipidemia, hyperlipidemia, ...
Pharmaceutical combinations of sofosbuvir and ribavirin
Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi
April 27, 2017 - N°20170112867

This invention is a novel pharmaceutical composition comprising sofosbuvir and ribavirin and at least one pharmaceutically acceptable excipient for use in the treatment of hepatitis c virus infections, chronic hepatitis c (chc), hepatocellular carcinoma or patients with end-stage liver disease awaiting liver transplantation.
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