Images List Premium Download Classic

Leukocyte

Leukocyte-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


loading
Igg subtyping assay for identifying transplantable tissue samples
Nj Sharing Network
June 08, 2017 - N°20170160278

The disclosure relates to methods for assessing the suitability of a tissue obtained from a vertebrate (e. G., human) donor for grafting to a recipient, such as another vertebrate of the same species. The method involves contacting leukocytes obtained from the donor with serum from the recipient. Binding between recipient antibodies and the leukocytes is assessed, specifically focusing on the ...
Erythrocyte aggregation and leukocyte isolation
General Electric Company
June 01, 2017 - N°20170153223

A device and/or methodology are described that include a mechanism for separating erythrocytes from other constituents of blood and for purifying leukocytes from blood. The separation and purification aspects may be provided in separate components or within the same component. The separation aspect assists in separating erythrocytes (red blood cells) from other cells in blood, such as by aggregation ...
Microfluidic device
California Institute Of Technology
May 18, 2017 - N°20170136463

Described herein are particular embodiments relating to a microfluidic device that may be utilized for cell sensing, counting, and/or sorting. Particular aspects relate to a microfabricated device that is capable of differentiating single cell types from dense cell populations. One particular embodiment relates a device and methods of using the same for sensing, counting, and/or sorting leukocytes from ...
Leukocyte Patent Pack
Download + patent application PDFs
Leukocyte Patent Applications
Download + Leukocyte-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Leukocyte-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Humanized mouse models and uses thereof
Champions Biotechnology, Inc
May 04, 2017 - N°20170118965

The invention relates generally to a humanized mouse model and uses thereof. Specifically, the invention relates to methods for generating, maintaining, and expanding a culture of leukocytes in heterologous animals. This invention also relates to use of these animals as models of human immune system for testing molecules in order to treat a disease or disorder such as cancer.
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
Immunomedics, Inc.
April 27, 2017 - N°20170114126

Severe glomerulonephritis involves cell necrosis as well as netosis, programmed neutrophil death leading to expulsion of nuclear chromatin and neutrophil extracellular traps (nets). Histones released by neutrophils undergoing netosis killed glomerular endothelial cells, podocytes, and parietal epithelial cells. This was prevented by histone-neutralizing agents anti-histone igg, activated protein c and heparin. Histone toxicity on glomeruli was tlr2/4-dependent. Anti-gbm glomerulonephritis ...
Pharmaceutical composition for treating cancer in an individual subject suffering cancer
Ma Shen Kai Ruei Co., Ltd.
April 27, 2017 - N°20170112856

A pharmaceutical composition for treating cancer in an individual, comprising at least a pharmaceutically effective amount of a novel target hcc reversal signal substance, and a pharmaceutically acceptable ingredient comprising a vehicle, a carrier, a diluent or an excipient; and the novel target hcc reversal signal substance is a mixture that consisting of antroquinonol (aql), antrocinnamonin a (aca), antroquinonol b (...
Leukocyte Patent Pack
Download + patent application PDFs
Leukocyte Patent Applications
Download + Leukocyte-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Leukocyte-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Detection of shed cd31, diagnosis of atherothrombosis and autoimmune disorders, and methods for analyzing signaling ...
Institut National De La Sante Et De La Recherche Medicale (inserm)
March 16, 2017 - N°20170074891

The present invention stems from the finding that the extracellular domain of cd31 proteins present on blood leukocytes is shed and released in the circulation as a soluble form of cd31. A method for detecting shed cd31 is further disclosed. The invention therefore relates to a method for detecting a shed ectodomain of a transmembrane protein such as cd31 and ...
Integrated leukocyte, oxygen and/or co2 depletion, and plasma separation filter device
New Health Sciences, Inc.
March 16, 2017 - N°20170072339

A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein the membrane forms an inner chamber; a leukocyte and oxygen and/or carbon dioxide depletion media disposed wherein the inner chamber, the leukocyte and oxygen and/...
Peptides that block leukocyte recruitment and methods of use
Arch Cancer Therapeutics, Inc.
March 16, 2017 - N°20170072006

Disclosed are novel peptides comprising seq id no: 1 and modifications thereof, which are effective in blocking leukocyte recruitment. The disclosed peptides are useful for treating diseases associated with leukocyte recruitment for example inhibiting metastasis of a solid tumor to the liver and lungs and for treating sepsis. Also disclosed are methods of screening for compounds having the ability to block ...
Pharmaceutical composition comprising an anti-cd6 monoclonal antibody used in the diagnosis and treatment of rheumatoid ...
Centro De Inmunologia Molecular
March 09, 2017 - N°20170066835

The present invention is related to the branch of immunology and particularly with the generation of pharmaceutical compositions containing a humanized monoclonal antibody recognizing the leukocyte differentiation antigen cd6. Accordingly with that statement, the purpose of this invention is to provide pharmaceutical compositions which contain a humanized anti-monoclonal antibody for the diagnosis and treatment of autoimmune diseases, particularly the rheumatoid ...
Metabolic and genetic biomarkers for memory loss
University Of Rochester
February 23, 2017 - N°20170052204

The present invention relates to methods of determining if a subject has an increased risk of suffering from memory impairment. The methods comprise analyzing at least one plasma sample from the subject to determine a value of the subject's lipidomic profile, and also analyzing the gene expression profile from leukocytes and comparing the value of the subject's biomarker profile (lipidomic ...
Method and device for conserving viable and functional human polymorphonuclear neutrophils
Institut National De La Sante Et De La Recherche Medicale (inserm)
February 23, 2017 - N°20170051253

A method for keeping leukocytes alive ex vivo or in vitro, comprising maintaining the leukocytes in a medium comprising from 3 to 10 mm of glucose, in hypoxic conditions with p(02)≦10 mm hg.
Inhibitors of human phosphatidylinositol 3-kinase delta
Icos Corporation
February 23, 2017 - N°20170049772

Methods of inhibiting phosphotidylinositol 3-kinase delta isoform (pi3kδ) activity, and methods of treating disease, such as disorders of immunity and inflammation, in which pi3kδ plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit pi3kδ, while not significantly inhibiting activity of other pi3k ...
Leukocyte Patent Pack
Download + patent application PDFs
Leukocyte Patent Applications
Download + Leukocyte-related PDFs
For professional research & prior art discovery
inventor
  • + full patent PDF documents of Leukocyte-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Methods of treating and preventing staphylococcus aureus infections and associated conditions
New York University
January 12, 2017 - N°20170008953

The present invention relates to methods and compositions for preventing and treating staphylococcus aureus in a subject. Therapeutic compositions of the present invention comprise leukocidin e and/or d proteins or polypeptides and anti-leukocidin e and/or d antibodies. The invention further relates to methods of identifying inhibitors of luke/d cytotoxicity and inhibitors of luke/d-leukocyte binding.
Protease-resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
Mesoblast International Sàrl
December 29, 2016 - N°20160375100

The present invention features mutant stromal cell derived factor-1 (sdf-1) peptides that have been mutated to make them resistant to digestion by, for example, the proteases dipeptidyl peptidase iv (dppiv), matrix metalloproteinase-2 (mmp-2), matrix metalloproteinase-9 (mmp-9), leukocyte elastase, cathepsin g, carboxypeptidase m, and carboxypeptidase n, but which retain chemoattractant activity.
Cancer vaccine composition
International Institute Of Cancer Immunology, Inc.
December 22, 2016 - N°20160367649

A cancer vaccine composition for human leukocyte antigen (hla)-a*0206-positive persons, comprising a protein product of the tumor suppressor gene wt1 or a partial peptide thereof.
Methods and compounds for modulating the secretion or expression of adhesion proteins or angiopoietins of ...
Pacific Arrow Limited
December 08, 2016 - N°20160354397

This invention provides methods, processes, compounds and compositions for modulating the gene expression or secretion of adhesion proteins, angiopoietins or their receptors to cure diseases, for anti-angiogenesis and for treating parasites, wherein the adhesion proteins or receptors comprise fibronectin, integrins family, myosin, vitronectin, collagen, laminin, glycosylation cell surface proteins, polyglycans, cadherin, heparin, tenascin, cd 54, cam, elastin and fak; wherein the ...
Integrated electrical profiling system for measuring leukocytes activation from whole blood
Massachusetts Institute Of Technology
November 17, 2016 - N°20160331297

A system includes a microfluidic device configured to isolate one or more particles from a mixture, a flow rate matching device configured to match flow rate of the microfluidic device with flow rate of an electrical measurement device configured to measure an electrical property of the isolated particles, and an electrical measurement device configured to measure an electrical property of ...
Substituted aminopyrimidine compounds and methods of use
Sunshine Lake Pharma Co., Ltd.
November 03, 2016 - N°20160318914

The invention relates to the preparation and use of new aminopyrimidine derivatives as drug candidates in free form or in pharmaceutically acceptable salt form and formulations thereof for the modulation of a disorder or disease which is mediated by the activity of the pi3k enzymes. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using ...
Substituted aminopyrimidine compounds and methods of use
Calitor Sciences, Llc
November 03, 2016 - N°20160318913

The invention relates to the preparation and use of new aminopyrimidine derivatives as drug candidates in free form or in pharmaceutically acceptable salt form and formulations thereof for the modulation of a disorder or disease which is mediated by the activity of the pi3k enzymes. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using ...
T cell modulator
Calitor Sciences, Llc
November 03, 2016 - N°20160317615

Compositions, methods of use, and pharmaceutical preparations useful for modulation of immune responses are disclosed herein. In one embodiment a composition is extracted from immune organs or leukocytes derived from members of the chondrichthyes family through dialysis. Said immune modulator is useful for treatment of conditions requiring stimulations or regulation of immunity. In one embodiment, said immunomodulator controls t cell ...
Loading