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|| List of recent L Amino Acid-related patents
|Compositions and methods for controlling the weight of animals|
Compositions are provided comprising a balance between lysine and essential amino acids and metabolizable enemy. The compositions are useful in methods to prevent or treat obesity in an animal without concomitant loss of lean muscle mass.
|Derivatives of growth hormone and related proteins, and methods of use thereof|
The growth hormone supergene family comprises greater than 20 structurally related cytokines and growth factors. A general method is provided for creating site-specific, biologically active conjugates of these proteins.
|Charged nutritive proteins and methods|
Charged nutritive proteins are provided. In some embodiments the nutritive proteins an aqueous solubility of at least 12.5 g/l at ph 7.
|Culture medium for eukaryotic cells|
The invention pertains to the use of amino acid derivatives selected from n-acetyl amino acids, γ-glutamyl amino acids, pyroglutamyl amino acids, glutamate-containing or proline-containing dipeptides, oxo-aminoacids, homo-aminoacids, and glycyl-glycine, as a growth- and production promoting ingredient, in culture media for culturing eukaryotic cells. The invention further pertains to culture media containing these amino acid derivatives at levels of at least 0.001 mg/l..
|Method of enhancing muscle protein synthesis|
The present invention relates to a method of enhancing muscle protein synthesis following physical exertion comprising administering to a human a composition comprising protein or essential amino acids and carbohydrates 30 minutes or less prior to, during, or within 30 minutes of running repeated sprints. Further, the invention relates to a program for enhancing muscle adaptation resulting from repeated sprints training..
|Culture medium composition for culturing amnion-derived mesenchymal stem cell, and method for culturing amnion-derived mesenchymal stem cell by using same|
The present invention relates to a medium for culturing mesenchymal stem cells, and more particularly to a medium composition for culturing mesenchymal stem cells, which contains basal medium, l-ascorbic acid 2-phosphate, fetal bovine serum, basic fibroblast growth factor (b-fgf), non-essential amino acids (neaas), insulin, n-acetyl-l-cysteine, calcium chloride, and hydrocortisone, and a method of culturing mesenchymal stem cells using the same. According to the present invention, a number of mesenchymal stem cells required for stem cell therapy can be obtained in a short time, and the ability of mesenchymal stem cells to differentiate is improved so that they are useful for stem cell therapy..
|High protein supplement|
The present disclosure relates to high protein dietary supplements for treating various symptoms and diseases associated with protein deficiency including weight gain, obesity, catabolic diseases, fibromyalgia, anxiety reactions, posttraumatic stress and chronic fatigue syndrome. Embodiments of dietary supplements comprise combinations of proteins, essential and semi-essential amino acids including l-lysine, l-arginine, and/or l-histidine..
|Low protein infant formula with increased essential amino acids|
The present invention concerns an improved balance of the essential branched chain amino acids leucine, isoleucine and valine in infant formula.. .
|Human epidermis-derived mesenchymal stem cell-like pluripotent cells and preparation method thereof|
The invention discloses a cell culture medium, human epidermis-derived mesenchymal stem cell-like pluripotent cells and a preparation method thereof. The culture medium is formed by adding fetal bovine serum, hbfgf, hscf, non-essential amino acids, l-glutamine and gentamicin into a dmem culture medium with the glucose content of 0.5-5 g/l, wherein every 100 ml of the final culture medium contains 10-25% by volume percent of fetal bovine serum, 100-4000 ng of the hbfgf, 10-2000 ng of hscf, 0.1-2 ml of 100× non-essential amino acids, 0.1-2 ml of pbs solution containing 3% by mass percent of l-glutamine and 1000-8000 u of gentamicin.
|Stem cell defined media for xeno-free and feeder free conditions and uses thereof|
The invention provides a defined low protein culture medium for maintaining cells in an undifferentiated state, the medium comprising: a basal medium, an organic acid from the tricarboxylic acid cycle, nonessential amino acids, a combination of growth factors selected from the group consisting of fgf-2 protein, an igf-1 protein or insulin, a transferrin protein, and a tgf beta 1 protein, wherein the medium is essentially feeder-free, essentially xeno-free, essentially free of beta-mercaptoethanol, and essentially free of animal-derived or human-derived proteins.. .
|Metabolic maturation in stem cell-derived tissue cells|
The present invention concerns methods and compositions for promoting a conversion in stem cells or cells derived therefrom from glycolysis to aerobic respiration and its associated pathways, including oxidative phosphorylation, the tca cycle, fatty acid oxidation, and pyruvate decarboxylation, for example. In specific embodiments, certain media is employed to improve metabolic maturation of particular stem cell-derived cells, including human embryonic stem cells and human induced pluripotent stem cells, for example.
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L Amino Acid topics: Amino Acid, Amino Acid Sequence, Amino Acids, Recombinant, Polypeptide, Nucleotide, Nucleic Acid, Hla Antigen, Lymphocyte, Cytotoxic T Lymphocyte, Immunogenic, Oligonucleotide, Antidiabetic Agent, Immobilize, Chemical Reaction
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