Follow us on Twitter
twitter icon@FreshPatents


Kinetics patents

      

This page is updated frequently with new Kinetics-related patent applications.




 Methods for detecting a biomarker by alternating current electrokinetics patent thumbnailMethods for detecting a biomarker by alternating current electrokinetics
Methods are described for detecting pathogens, infectious diseases, and physiological conditions by quantifying change of impedance over time of when a biological sample is applied onto a lab-on-a-chip. The lab-on-a-chip utilizes alternating-current electrokinetic (acek) phenomena such that molecules move or are carried in an electric field generated by the application of an electrical signal of predetermined magnitude and frequency to an electrode array of the lab-on-a-chip..
University Of Tennessee Research Foundation


 Assessment of blood coagulation using an acoustic radiation force based optical coherence elastography (arf-oce) patent thumbnailAssessment of blood coagulation using an acoustic radiation force based optical coherence elastography (arf-oce)
An apparatus and method of using an optical coherence elastography (oce) under acoustic radiation force (arf) excitation includes the steps of inducing an excitation wave in a blood sample by use of an ultrasound beam from an ultrasonic transducer; measuring an elastic property of the blood sample by use of an optical coherence tomography (oct) beam transverse to the ultrasound beam to dynamically measure the elastic property of the blood sample during coagulation and assessing the clot formation/dissolution kinetics and strength.. .
The Regents Of The University Of California


 Electrical power generation systems and methods regarding same patent thumbnailElectrical power generation systems and methods regarding same
A solid or liquid fuel to plasma to electricity power source that provides at leas; one of electrical and thermal power comprising (i) at least one reaction cell for the catalysis of atomic hydrogen to form hydrinos, (ii) a chemical feel mixture comprising at least two components chosen from: a source of h2o catalyst or h2o catalyst; a source of atomic hydrogen or atomic hydrogen; reactants to form the source of h2o catalyst or h2o catalyst and a source of atomic hydrogen or atomic hydrogen; one or more reactants to initiate the catalysis of atomic hydrogen; and a material to cause the feel to be highly conductive, (iii) a fuel injection system such as a railgun shot injector, (iv) at least one set of electrodes that confine the fuel and an electrical power source that provides repetitive short bursts of low-voltage, high-current electrical energy to initiate rapid kinetics of the hydrino reaction and an energy gain due to forming hydrinos to torn! a brilliant-light emitting plasma, (v) a product recovery system such as at least one of an augmented plasma railgun recovery system and a gravity recovery system (vi) a fuel pelletizer or shot maker comprising a s me her. A source or hydrogen and a source of h2o, a dripper and a water bath to form fuel pellets or shot, and an agitator to teed shot into the injector, and (vii) a power converter capable of converting the high-power light output of the cell into electricity such as a concentrated solar power device comprising a plurality of ultraviolet (uv) photoelectric cells or a plurality of photoelectric cells, and a uv window..
Brilliant Light Power, Inc


 Formulation methodology for distortional thermosets patent thumbnailFormulation methodology for distortional thermosets
And a diamine curing agent. The resultant distortional thermoset compositions possess superior out-life requirements and advantageous reaction kinetics for preparing prepreg compositions and materials..

 Optimized variants of anti-vegf antibodies patent thumbnailOptimized variants of anti-vegf antibodies
The present invention provides anti-vegf antibodies and compositions that include anti-vegf antibodies (e.g., antibody conjugates, fusion proteins, and polymeric formulations), and uses thereof, for example for treatment of disorders associated with pathological angiogenesis. The present invention also provides methods of identifying antibody variants with improved properties, for example, enhanced binding affinity, stability, pharmacokinetics, and/or expression..
Genentech, Inc.


 Physical self-organizing hydrogel system for biotechnological applications patent thumbnailPhysical self-organizing hydrogel system for biotechnological applications
A physical self-organizing hydrogel system for biotechnological applications composed of a non-covalent network on the basis of a protein-ligand interaction includes a tetrameric protein and biotin or a derivative thereof as a ligand, wherein biotin or derivative is covalently conjugated to an end of a polymer chain or a linear or multi-arm synthetic polymer of a single-or double-strand oligonucleotide and wherein the solid content in relation to the entire hydrogel is at least 3% and the conjugates are crosslinked by the tetrameric protein. A mixture ratio is a molar equivalent ratio between the protein and the number of terminal biotinylated ends of the polymer chains in the biotin-polymer conjugate of 1:2 to 1:8.
Technische UniversitÄt Dresden


 Modified antibiotic peptides having variable systemic release patent thumbnailModified antibiotic peptides having variable systemic release
The invention relates to modified antibiotic peptides, in particular derivatives of apidaecin and oncocin, preferably having increased stability, reduced immunoreaction, and improved pharmacokinetics. In the invention, the peptide antibiotics are reversibly protected by means of a linker having the polymer polyethylene glycol (peg).
Universitat Leipzig


 Method and composition for the treatment of opioid induced constipation patent thumbnailMethod and composition for the treatment of opioid induced constipation
The invention relates to a method of treatment using a solid oral pharmaceutical dosage form comprising an opioid receptor antagonist for use in the treatment of opioid induced constipation comprising the opioid antagonist equivalent to 24 mg of naloxone hydrochloride as twice daily formulation or equivalent to 48 mg of naloxone hydrochloride as once daily formulation, characterized in that the opioid antagonist has a rapid first pass metabolism with a plasma half-life of 2 hours or less in humans within the first 3 hours of oral administration of a solution, wherein the steady state pharmacokinetics result in a constant level of naloxone in the bloodstream, wherein the pharmacokinetics are independent of whether the dosage is administered once or twice daily, wherein the oral dosage form releases the opioid antagonist in a prolonged manner, wherein the in vitro release rate of the opioid antagonist measured using the paddle stirrer method according to ph. Eur.
Develco Pharma Schweiz Ag


 Formulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2 patent thumbnailFormulations pharmacokinetics of deuterated benzoquinoline inhibitors of vesicular monoamine transporter 2
The present invention relates to new pharmaceutical compositions comprising benzoquinoline compounds, and methods to inhibit vesicular monoamine transporter 2 (vmat2) activity in a subject for the treatment of chronic hyperkinetic movement disorders.. .
Auspex Pharmaceuticals, Inc.


 Controlled release and taste masking oral pharmaceutical composition patent thumbnailControlled release and taste masking oral pharmaceutical composition
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. A structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices.
Cosmo Technologies Limited


Compositions and methods for modified dendrimer nanoparticle delivery

Compositions and methods for modified dendrimer nanoparticle (“mdnp”) delivery of therapeutic, prophylactic and/or diagnostic agent such as large reprna molecules to the cells of a subject have been developed. Mdnps efficiently drive proliferation of antigen-specific t cells against intracellular antigen, and potentiate antigen-specific antibody responses.
Whitehead Institute For Biomedical Research

Hybrid system for storing solar energy as heat and electricity

A photoelectrochemical system and method utilizing the photons having energies above the bandgaps of a p-type semiconductor photocathode and an n-type semiconductor photoanode with redox couples having fast electron transfer kinetics to keep overpotentials under 0.15 volts, and redox potentials energetically located within the band gaps, for storing energy in photodriven oxidation and reduction reactions separated by less than 1.6 volts using a redox flow battery configuration, are described. The photoelectrochemical system can also store heat in the flow battery generated from the inefficiencies of the photoredox reactions and from impinging photons having energies below the band gaps.
University Of Wyoming

Apparatus and assessing tissue treatment

The invention relates to a tissue monitoring apparatus, a tissue monitoring method and an ablation lesion monitoring, measuring, and controlling automated algorithm incorporating diffuse reflectance spectroscopy (drs) and/or arrhenius model thermal denaturation kinetics for determining the characteristics of the lesion or the tissue, especially for identifying the transmurality of the ablation lesion. The invention pertains to a device for and method of real time monitoring of lesion formation as ablation is being carried out..

Photovoltaic power generation systems and methods regarding same

A solid fuel power source that provides at least one of electrical and thermal power comprising (i) at least one reaction, cell for the catalysis of atomic hydrogen to form hydrinos, (ii) a chemical fuel mixture comprising at least two components chosen from: a source of h2o catalyst or h2o catalyst; a source of atomic hydrogen or atomic hydrogen; reactants to form the source of h2o catalyst or h2o catalyst and a source of atomic hydrogen or atomic hydrogen; one or more reactants to initiate the catalysis of atomic hydrogen; and a material to cause the fuel to be highly conductive, (iii) at least one set of electrodes that confine the fuel and an electrical power source that provides a short burst of low-voltage, high-current electrical energy to initiate rapid kinetics of the hydrino reaction and an energy gain due to forming hydrinos, (iv) a product recovery systems such as a vapor condenser, (v) a reloading system, (vi) at least one of hydration, thermal, chemical, and electrochemical systems to regenerate the fuel from the reaction products, (vii) a heat sink that accepts the heat from the power-producing reactions, (viii) a photovoltaic power converter comprising at least one of a concentrated solar power device, and at least one triple-junction photovoltaic cell, monocrystalline cell, polycrystalline cell, amorphous cell, string/ribbon silicon cell, multi-junction cell, homojunction cell, heterojunction cell, p-i-n device, thin-film cells, dye-sensitized cell, and an organic photovoltaic cell, and an antireflection coating, an optical impedance matching coating, and a protective coating.. .
Brilliant Light Power, Inc.

N-terminal derivatisation of proteins with polysaccharides

The present invention relates to methods for producing n-terminal derivatives of proteins in which a polysaccharide, preferably having at least terminal sialic units, and preferably consisting essentially only of sialic acid units, is reacted at the n-terminus of a protein or peptide under controlled conditions to produce an n-terminal derivative. The controlled conditions include use of acidic ph for the derivatisation step and a higher ph for purification.
Lipoxen Technologies Limited

Tetrameric cytokines with improved biological activity

The present invention concerns methods and compositions for forming cytokine-antibody complexes using dock-and-lock technology. In preferred embodiments, the cytokine-mab dnl complex comprises an igg antibody attached to two ad (anchor domain) moieties and four cytokines, each attached to a ddd (docking and dimerization domain) moiety.
Ibc Pharmaceuticals, Inc.

Method of providing sustained analgesia with buprenorphine

A method of effectively treating pain in humans is achieved by administering buprenorphine in accordance with first order kinetics over an initial three-day dosing interval, such that a maximum plasma concentration from about 20 pg/ml to about 1052 pg/ml is attained, and thereafter maintaining the administration of buprenorphine for at least an additional two-day dosing interval in accordance with substantially zero order kinetics, such that the patients experience analgesia throughout the at least two-day additional dosing interval.. .
Purdue Pharma L.p.

Bioreactor for the in situ study of microbial biofilms inducing corrosion on metal surfaces

A portable bioreactor is provided for the in situ study of mesophilic and thermophilic corrosion inducing microbial biofilms on metal surfaces used in any industry, such as oil, chemical, petrochemical, oil refining, food, metallurgical, paper. The bioreactor's configuration is a “batch” type for turbulent and piston-driven laminar flow, operating by cycles, with the continuous circulation of fluid.
Instituto Mexicano Del Petroleo

Programmable mip catch and release technology

Programmable molecular imprinted polymers (mips) that have modified binding site kinetics for target imprintable entities (ties) that operate to control the adsorption, binding, release and equilibrium distribution of related materials into and out of the mips, which are useful for the controlled adsorption, controlled release and control of concentrations of such materials in media including gases, liquids, fluids, biological systems, solutions and other environments. When a collective plurality of the mips with modified binding site kinetics are combined, the resulting mip systems can be tailored to exhibit pseudo zero- and first-order kinetics, as well as higher kinetic profiles, and when further combined with time-delay functionality, can be tailored to exhibit delayed uptake and release, ramped uptake and release of materials, step functions, polynomial, geometric, exponential and other unique kinetic profiles of material exchange between the novel mips and a fluid media that are not readily achievable by other means..
The Decaf Company, Llc

Programmable mip catch and release technology

Programmable molecular imprinted polymers (mips) that have modified binding site kinetics for target imprintable entities (ties) that operate to control the adsorption, binding, release and equilibrium distribution of related materials into and out of the mips, which are useful for the controlled adsorption, controlled release and control of concentrations of such materials in media including gases, liquids, fluids, biological systems, solutions and other environments. When a collective plurality of the mips with modified binding site kinetics are combined, the resulting mip systems can be tailored to exhibit pseudo zero- and first-order kinetics, as well as higher kinetic profiles, and when further combined with time-delay functionality, can be tailored to exhibit delayed uptake and release, ramped uptake and release of materials, step functions, polynomial, geometric, exponential and other unique kinetic profiles of material exchange between the novel mips and a fluid media that are not readily achievable by other means..
The Decaf Company, Llc

Programmable mip catch and release technology

Programmable molecular imprinted polymers (mips) that have modified binding site kinetics for target imprintable entities (ties) that operate to control the adsorption, binding, release and equilibrium distribution of related materials into and out of the mips, which are useful for the controlled adsorption, controlled release and control of concentrations of such materials in media including gases, liquids, fluids, biological systems, solutions and other environments. When a collective plurality of the mips with modified binding site kinetics are combined, the resulting mip systems can be tailored to exhibit pseudo zero- and first-order kinetics, as well as higher kinetic profiles, and when further combined with time-delay functionality, can be tailored to exhibit delayed uptake and release, ramped uptake and release of materials, step functions, polynomial, geometric, exponential and other unique kinetic profiles of material exchange between the novel mips and a fluid media that are not readily achievable by other means..
The Decaf Company, Llc

Integrated microarray printing and detection system for molecular binding analysis

A method and system for analysis of protein interaction kinetics in microarray or whole-cell based formats includes positioning a sensor chip on a prism. The sensor chip is spotted with a plurality of target molecules.
Arizona Board Of Regents On Behalf Of Arizona State University

Nmr in kinetics of hydrocarbon generation

Disclosed are methods of characterizing kerogen and its hydrocarbon generation potential using nmr as the primary analytical tool, and using such data to derive the kinetics of hydrocarbon generation and alteration, thus predicting the hydrocarbon potential of source rock in geological setting, which can then be used in petroleum exploration and production.. .
Conocophillips Company

Manufacturing of a ceramic article from a metal preform or metal matrix composite preform provided by 3d-printing or 3d-weaving

The present invention relates to a method of manufacturing a ceramic article (3) from a metal or metal matrix composite preform (1) provided by 3d-printing or by 3d-weaving. The preform (1) is placed in a heating chamber (2), and a predetermined time-temperature profile is applied in order to controllably react the preform (1) with a gas introduced into the heating chamber (2).
European Space Agency

Abuse and misuse deterrent transdermal systems

An abuse deterrent and misuse deterrent transdermal patch comprising aversive agents incorporated in the backing layer of the patch. The aversive agents can exhibit biphasic or sustained kinetics of release with an immediate portion released rapidly and an extended portion released in a prolonged manner when exposed to a dissolution medium.
4p Therapeutics

Antibodies with modified affinity to fcrn that promote antigen clearance

The present inventors discovered that antigen uptake into cells is facilitated by an antibody having human fcrn-binding activity at the plasma ph and a lower antigen-binding activity at the early endosomal ph than at the plasma ph; such antibodies can increase the number of antigens to which a single antibody molecule can bind; the reduction of antigen in plasma can be facilitated by administering such an antibody; and antibody pharmacokinetics can be improved by using such antibodies.. .

Antibodies with modified affinity to fcrn that promote antigen clearance

The present inventors discovered that antigen uptake into cells is facilitated by an antibody having human fcrn-binding activity at the plasma ph and a lower antigen-binding activity at the early endosomal ph than at the plasma ph; such antibodies can increase the number of antigens to which a single antibody molecule can bind; the reduction of antigen in plasma can be facilitated by administering such an antibody; and antibody pharmacokinetics can be improved by using such antibodies.. .

Electronic measurements of monolayers following homogenous reactions of their components

The disclosure relates to novel methods for performing a solution based assay reaction with an electroactive active moiety (eam) that subsequently forms a self-assembled monolayer (sam) utilizing the advantages of faster solution reaction kinetics, sam protected electrode and surface based electrochemistry for electronic measurement.. .
Ohmx Corporation

Method for printing three-dimensional parts with crystallization kinetics control

A method for printing a three-dimensional part with an additive manufacturing system, which includes providing a part material that compositionally has one or more semi-crystalline polymers and one or more secondary materials that are configured to retard crystallization of the one or more semi-crystalline polymers, where the one or more secondary materials are substantially miscible with the one or more semi-crystalline polymers. The method also includes melting the part material in the additive manufacturing system, forming at least a portion of a layer of the three-dimensional part from the melted part material in a build environment, and maintaining the build environment at an annealing temperature that is between a glass transition temperature of the part material and a cold crystallization temperature of the part material..
Stratasys, Inc.

Compositions and methods of use of immunotoxins comprising ranpirnase (rap) show potent cytotoxic activity

The present invention concerns methods and compositions for forming immunotoxin complexes having a high efficacy and low systemic toxicity. In preferred embodiments, the toxin moiety is a ranpirnase (rap), such as rap(q).
Ibc Pharmaceuticals, Inc.

3'-oh unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing

The present invention relates generally to 3′-oh unblocked nucleotides and nucleosides labeled and unlabeled with 5-methoxy-substituted nitrobenzyl-based photocleavable terminating groups for use in methods and systems related to dna and rna sequencing and analysis. These compounds may be used as reversible terminators as they exhibit fast nucleotide incorporation kinetics, single-base termination, high nucleotide selectivity, and rapid terminating group cleavage that results in a naturally occurring nucleotide..
Lasergen, Inc.

In-line detection of chemical compounds in beer

Apparatus, methods, and systems for in-line detection of chemical compounds in beer are provided. In these apparatus, methods, and systems, a small sample of wort is removed from a fermentation vessel, heated, analyzed by infrared attenuated total reflectance (ir-atr) spectroscopy, and returned to the fermentation vessel.

Implantable polymeric device for sustained release of buprenorphine

The present invention provides compositions, methods, and kits for treatment of opiate addiction and pain. The invention provides a biocompatible nonerodible polymeric device which releases buprenorphine continuously with generally linear release kinetics for extended periods of time.
Titan Pharmaceuticals, Inc.

April variants

The present invention provides a variant proliferation-inducing ligand (april), which has a higher binding affinity to bcma than wild-type april; and/or altered binding kinetics compared with wild-type april, and/or a higher bcma:taci (transmembrane activator and calcium modulator and cyclophilin ligand interactor) binding ratio than wild-type april and which comprises mutations at one or more of the following positions: a125, v174, t175, m200, p201, s202, h203, d205 and r206.. .
Ucl Business Plc

Pharmacokinetics of s-adenosylmethionine formulations

Compositions and methods to improve the pharmacokinetic profile of s-adenosylmethionine (same) are provided, as are methods of treating various disorders using same formulations with improved pharmacokinetic profiles. More specifically, the invention is directed to methods of treating a disease or disorder in a subject and/or improving the nutritional status of a subject by administering formulations exhibiting improved pharmacokinetic profiles of exogenous same.
Methylation Sciences International Srl

Compositions and methods for inhibiting cytochrome p450

Methods of inhibiting cytochrome p450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome p450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome p450 enzymes..
Sequoia Pharmaceuticals, Inc.

Uniform, high basis weight nanofiber fabrics for medical applications

Described herein are devices, compositions and methods relating to the production of high basis weight, non-woven nanofiber polymer fabrics. In certain embodiments, described herein are modifications to free-surface, needle-less or nozzle-less electrospinning devices that permit the production of such high basis weight, non-woven nanofiber polymer fabrics.
University Of Washington

In vitro pharmacokinetics/pharmacodynamics bellows perfusion system for enhancing effectiveness of cancer chemotherapy

Provided herein is a continuous cell perfusion model system that provides useful pharmacokinetic and pharmacodynamic information on the application of new drugs or combinations of various agents in vitro to human cancer cell lines. Also provided are methods of using this system to individualize cancer treatment..

Metal hydride alloys with improved rate performance

Methods of preparing improved metal hydride alloy materials are provided. The alloys include a mixture of at least four of vanadium, titanium, nickel, chromium, and iron.
California Institute Of Technology

Multimeric complexes with improved in vivo stability, pharmacokinetics and efficacy

The present invention concerns multimeric complexes based on antibody fusion proteins comprising an ad moiety attached to the c-terminal end of each antibody light chain. The complexes further comprise effector moities attached to ddd moieties.
Ibc Pharmaceuticals, Inc.

Infusion pump drug delivery profiles, systems, and methods

Embodiments relate generally to drug delivery infusion profiles that can be transferred and executed on infusion pumps without the need for loading new firmware. Particularly, embodiments relate to integrating and/or editing delivery profiles for execution infusion systems.
Smiths Medical Asd, Inc.

Poly(vinyl benzoate) nanoparticles for molecular delivery

The present invention comprises poly(vinyl benzoate) nanoparticle suspensions as molecular carriers. These nanoparticles can be formed by nanoprecipitation of poly(vinyl benzoate) in water using pluronic f68 as surfactant, to create spherical nanostructures measuring about 200-250 nm in diameter which are stable in phosphate buffer and blood serum, and only slowly degrade in the presence of esterases.
University Of South Florida

Enhancing the physical properties of semi-crystalline polymers via solid-state shear pulverization

Solid-state shear pulverization of semi-crystalline polymers and copolymers thereof and related methods for enhanced crystallization kinetics and physical/mechanical properties.. .

Paired laser and electrokinetic separation, manipulation, and analysis device

The combined value of integrating optical forces and electrokinetics allows for the pooled separation vectors of each to be applied, providing for separation based on combinations of features such as size, shape, refractive index, charge, charge distribution, charge mobility, permittivity, and deformability. The interplay of these separation vectors allow for the selective manipulation of analytes with a finer degree of variation.
The Government Of The United States Of America, As Represented By The Secretary Of The Navy

Catalytic effects of oxygen carrier based chemicl-looping reforming of ch4 with co2

The invention relates to ceo2 and la2o3 for catalyzing fe2o3—al2o3 based chemical-looping reforming of ch4 with co2 (cl-drm). The reaction performance of all the composite oxygen carriers was evaluated in a fixed-bed reactor at atmospheric pressure condition.
University Of Wyoming



Kinetics topics:
  • Medical Device
  • Polypeptide
  • Nucleic Acid
  • Nucleic Acids
  • Specificity
  • Surfactant
  • Enhancement
  • Scattering
  • Electrolyte
  • Conductive Elements
  • Amplification
  • Red Blood Cell
  • Red Blood Cells
  • Antibodies
  • Luciferase


  • Follow us on Twitter
    twitter icon@FreshPatents

    ###

    This listing is a sample listing of patent applications related to Kinetics for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Kinetics with additional patents listed. Browse our RSS directory or Search for other possible listings.


    0.4397

    file did exist - 2345

    2 - 1 - 52