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Kinetics

Kinetics-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Antibodies with modified isoelectric points
Xencor, Inc.
June 22, 2017 - N°20170174757

The invention relates generally to compositions and methods for altering the isoelectric point of an antibody, and in some cases, resulting in improved plasma pharmacokinetics, e. G. Increased serum half-life in vivo.
NEW Long-acting recombinant human follicle-stimulating hormone-fc fusion protein
Unicomed Pharma Co. Ltd.
June 22, 2017 - N°20170174736

Recombinant fc fusion proteins of human follicle-stimulating hormone (hfsh) with in vivo biological activities comparable to those of human follicle-stimulating hormone are disclosed. A recombinant hfsh-fc fusion protein comprises β subunit of hfsh (hfsh β), ctp, α subunit of hfsh (hfsh α), a flexible peptide linker, and human igg2 fe variant (vigg2fc). A method is ...
Modular method to prepare tetrameric cytokines with improved pharmacokinetics by the dock-and-lock (dnl) technology
Ibc Pharmaceuticals, Inc.
June 15, 2017 - N°20170166651

The present invention concerns methods and compositions for forming cytokine-antibody complexes using dock-and-lock technology. In preferred embodiments, the cytokine-mab dnl complex comprises an igg antibody attached to two ad (anchor domain) moieties and four cytokines, each attached to a ddd (docking and dimerization domain) moiety. The ddd moieties form dimers that bind to the ad moieties, resulting in a 2:1 ratio ...
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Novel indocyanine compound, synthesis method and purification method thereof, diagnostic composition using the indocyanine compound, ...
National University Corporation Nagoya University
June 08, 2017 - N°20170157273

The present invention aims at providing a novel indocyanine compound solving problems of conventionally used indocyanine green, such as solubility in water or physiological saline, a synthesis method and a purification method thereof, and a diagnostic composition including the novel indocyanine compound. Further, provided are a method for evaluating biokinetics of the novel indocyanine compound and a device for measuring ...
Methods of improving the pharmacokinetics of doxepin
Pernix Sleep, Inc.
June 08, 2017 - N°20170157140

Methods of improving the pharmacokinetics of doxepin in a patient.
Method of determining concentration values of an analyte
Pernix Sleep, Inc.
May 25, 2017 - N°20170146512

A method for calibrating a measurement signal and/or for tracking a quantitative variable comprises the measuring of an analyte which exists in a solution with a certain concentration and has predetermined decay kinetics and the generating of a continuous measurement signal having decay kinetics at least corresponding to those of the analyte. The decay kinetics of the measurement signal ...
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Kinetics Patent Applications
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  • 99+ full patent PDF documents of Kinetics-related inventions.
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Polynucleotides encoding mutant hydrolase proteins with enhanced kinetics and functional expression
Promega Corporation
May 18, 2017 - N°20170137793

The invention provides a mutant hydrolase protein with enhanced kinetics and functional expression, as well as polynucleotides encoding the mutant proteins and methods of using the polynucleotides and mutant proteins.
Microfluidic electrokinetic paper based devices
Technion Research & Development Foundation Limited
May 18, 2017 - N°20170136457

A paper-based micro fluidic device suitable for electrokinetics and particularly isotachophoresis (itp) and a kit comprising same is provided. Further, a method for the preparation of said paper-based micro fluidic device and a method of use thereof for the detection and/or separation of molecules of interest are provided.
Sorbents for carbon dioxide reduction from indoor air
Enverid Systems, Inc.
May 18, 2017 - N°20170136399

A sorbent for co2 reduction from indoor air from an enclosed space. In some embodiments, the sorbent comprises a solid support and an amine-based compound being supported by the support. The sorbent captures at least a portion of the co2 within the indoor air. The sorbent may be regenerated by streaming outdoor air through the sorbent to release at least ...
Formulations of active agents for sustained release
Phasebio Pharmaceuticals, Inc.
May 18, 2017 - N°20170136092

The present invention provides pharmaceutical formulations for sustained release when administered at cold temperatures, and methods for delivering a treatment regimen with a combination of sustained release and long half-life formulations. The invention provides improved pharmacokinetics for peptide and small molecule drugs.
Ige antibodies for the inhibition of tumor metastasis
The Board Of Trustees Of The Leland Stanford Junior University
May 11, 2017 - N°20170129965

The present invention provides novel ige antibodies useful for inhibiting or preventing metastatic cancer. Also provided are methods to inhibit tumor metastasis by modulating the activity of at least one non-tumor cell, treating a patient to inhibit or prevent tumor metastases of a primary solid tumor, treating metastatic carcinoma, reducing metastasis of carcinoma cells, and reducing the growth kinetics of ...
Apparatus and method for measurements of growth or dissolution kinetics of colloidal particles
Manta Instruments, Inc.
May 04, 2017 - N°20170122860

A system for determining the growth/dissolution rate of colloidal particles is disclosed and includes multiple light sources and multiple sensors. A light source is constructed to emit a beam of electromagnetic radiation at a specimen chamber that holds the colloidal particles. The chamber allows a portion of the combined beam to scatter perpendicularly or at some other angle to ...
Photo-controlled removal of targets in vitro and in vivo
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv
May 04, 2017 - N°20170122853

This disclosure provides ir700-molecule conjugates and methods of their use to remove (e. G., separate or isolate) a target from a sample in vivo or from a subject in vitro. It is shown herein that exposure of ir700 to near infrared (nir) light removes a portion of ir700, changing it from a hydrophilic molecule, to one that is hydrophobic, ...
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  • 99+ full patent PDF documents of Kinetics-related inventions.
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Method for improving pharmacokinetics
Roche Palo Alto Llc
May 04, 2017 - N°20170119739

The object of the present invention is to inhibit oxidative metabolism of a compound of formula i by co-administration with ritonavir, a cytochrome p450 inhibitor.
Methods for quantitative and enhanced-contrast molecular medical imaging using cross-modality correction for differing tracer kinetics
The Trustees Of Dartmouth College
May 04, 2017 - N°20170119330

An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of ...
Silicone hydrogels having a structure formed via controlled reaction kinetics
Johnson & Johnson Vision Care, Inc.
April 27, 2017 - N°20170114174

The present invention relates to a process comprising the steps of reacting a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component, and at least one diluent to form an ophthalmic device having an advancing contact angle of less than about 80°; and contacting the ophthalmic device with an aqueous extraction solution at an elevated extraction ...
Timed, pulsatile release systems
Adare Pharmaceuticals, Inc.
April 27, 2017 - N°20170112774

A unit multiparticulate dosage form for delivering one or more basic, active pharmaceutical ingredients into the body in need of such medications to achieve target pk (pharmacokinetics) profiles is described. The dosage form comprises one or more multicoated drug particles (beads, pellets, mini-/micro-tablets) having a barrier coating and a lag-time coating. Each timed pulsatile release (tpr) bead population exhibits ...
Motion capture and analysis system for assessing mammalian kinetics
Kinetisense Inc.
April 27, 2017 - N°20170112418

Computer-implemented methods and systems for con-currently capturing video imagery with a 3d infrared camera, an audio commentary, and at least one set of physiological data during a mammalian subject's performance of one or more selected musculoskeletal movements for use in assessments of their range of motions.
Methods for detecting a biomarker by alternating current electrokinetics
University Of Tennessee Research Foundation
April 20, 2017 - N°20170108493

Methods are described for detecting pathogens, infectious diseases, and physiological conditions by quantifying change of impedance over time of when a biological sample is applied onto a lab-on-a-chip. The lab-on-a-chip utilizes alternating-current electrokinetic (acek) phenomena such that molecules move or are carried in an electric field generated by the application of an electrical signal of predetermined magnitude and frequency to ...
Assessment of blood coagulation using an acoustic radiation force based optical coherence elastography (arf-oce)
The Regents Of The University Of California
April 20, 2017 - N°20170107558

An apparatus and method of using an optical coherence elastography (oce) under acoustic radiation force (arf) excitation includes the steps of inducing an excitation wave in a blood sample by use of an ultrasound beam from an ultrasonic transducer; measuring an elastic property of the blood sample by use of an optical coherence tomography (oct) beam transverse to the ultrasound ...
Electrical power generation systems and methods regarding same
Brilliant Light Power, Inc
April 13, 2017 - N°20170104426

A solid or liquid fuel to plasma to electricity power source that provides at leas; one of electrical and thermal power comprising (i) at least one reaction cell for the catalysis of atomic hydrogen to form hydrinos, (ii) a chemical feel mixture comprising at least two components chosen from: a source of h2o catalyst or h2o catalyst; a ...
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