Follow us on Twitter
twitter icon@FreshPatents


Kinetics patents

      

This page is updated frequently with new Kinetics-related patent applications.




 Nmr in kinetics of hydrocarbon generation patent thumbnailNmr in kinetics of hydrocarbon generation
Disclosed are methods of characterizing kerogen and its hydrocarbon generation potential using nmr as the primary analytical tool, and using such data to derive the kinetics of hydrocarbon generation and alteration, thus predicting the hydrocarbon potential of source rock in geological setting, which can then be used in petroleum exploration and production.. .
Conocophillips Company


 Manufacturing of a ceramic article from a metal preform or metal matrix composite preform provided by 3d-printing or 3d-weaving patent thumbnailManufacturing of a ceramic article from a metal preform or metal matrix composite preform provided by 3d-printing or 3d-weaving
The present invention relates to a method of manufacturing a ceramic article (3) from a metal or metal matrix composite preform (1) provided by 3d-printing or by 3d-weaving. The preform (1) is placed in a heating chamber (2), and a predetermined time-temperature profile is applied in order to controllably react the preform (1) with a gas introduced into the heating chamber (2).
European Space Agency


 Abuse and misuse deterrent transdermal systems patent thumbnailAbuse and misuse deterrent transdermal systems
An abuse deterrent and misuse deterrent transdermal patch comprising aversive agents incorporated in the backing layer of the patch. The aversive agents can exhibit biphasic or sustained kinetics of release with an immediate portion released rapidly and an extended portion released in a prolonged manner when exposed to a dissolution medium.
4p Therapeutics


 Antibodies with modified affinity to fcrn that promote antigen clearance patent thumbnailAntibodies with modified affinity to fcrn that promote antigen clearance
The present inventors discovered that antigen uptake into cells is facilitated by an antibody having human fcrn-binding activity at the plasma ph and a lower antigen-binding activity at the early endosomal ph than at the plasma ph; such antibodies can increase the number of antigens to which a single antibody molecule can bind; the reduction of antigen in plasma can be facilitated by administering such an antibody; and antibody pharmacokinetics can be improved by using such antibodies.. .

 Antibodies with modified affinity to fcrn that promote antigen clearance patent thumbnailAntibodies with modified affinity to fcrn that promote antigen clearance
The present inventors discovered that antigen uptake into cells is facilitated by an antibody having human fcrn-binding activity at the plasma ph and a lower antigen-binding activity at the early endosomal ph than at the plasma ph; such antibodies can increase the number of antigens to which a single antibody molecule can bind; the reduction of antigen in plasma can be facilitated by administering such an antibody; and antibody pharmacokinetics can be improved by using such antibodies.. .

 Electronic measurements of monolayers following homogenous reactions of their components patent thumbnailElectronic measurements of monolayers following homogenous reactions of their components
The disclosure relates to novel methods for performing a solution based assay reaction with an electroactive active moiety (eam) that subsequently forms a self-assembled monolayer (sam) utilizing the advantages of faster solution reaction kinetics, sam protected electrode and surface based electrochemistry for electronic measurement.. .
Ohmx Corporation


 Method for printing three-dimensional parts with crystallization kinetics control patent thumbnailMethod for printing three-dimensional parts with crystallization kinetics control
A method for printing a three-dimensional part with an additive manufacturing system, which includes providing a part material that compositionally has one or more semi-crystalline polymers and one or more secondary materials that are configured to retard crystallization of the one or more semi-crystalline polymers, where the one or more secondary materials are substantially miscible with the one or more semi-crystalline polymers. The method also includes melting the part material in the additive manufacturing system, forming at least a portion of a layer of the three-dimensional part from the melted part material in a build environment, and maintaining the build environment at an annealing temperature that is between a glass transition temperature of the part material and a cold crystallization temperature of the part material..
Stratasys, Inc.


 Compositions and methods of use of immunotoxins comprising ranpirnase (rap) show potent cytotoxic activity patent thumbnailCompositions and methods of use of immunotoxins comprising ranpirnase (rap) show potent cytotoxic activity
The present invention concerns methods and compositions for forming immunotoxin complexes having a high efficacy and low systemic toxicity. In preferred embodiments, the toxin moiety is a ranpirnase (rap), such as rap(q).
Ibc Pharmaceuticals, Inc.


 3'-oh unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing patent thumbnail3'-oh unblocked, fast photocleavable terminating nucleotides and methods for nucleic acid sequencing
The present invention relates generally to 3′-oh unblocked nucleotides and nucleosides labeled and unlabeled with 5-methoxy-substituted nitrobenzyl-based photocleavable terminating groups for use in methods and systems related to dna and rna sequencing and analysis. These compounds may be used as reversible terminators as they exhibit fast nucleotide incorporation kinetics, single-base termination, high nucleotide selectivity, and rapid terminating group cleavage that results in a naturally occurring nucleotide..
Lasergen, Inc.


 In-line detection of chemical compounds in beer patent thumbnailIn-line detection of chemical compounds in beer
Apparatus, methods, and systems for in-line detection of chemical compounds in beer are provided. In these apparatus, methods, and systems, a small sample of wort is removed from a fermentation vessel, heated, analyzed by infrared attenuated total reflectance (ir-atr) spectroscopy, and returned to the fermentation vessel.

Implantable polymeric device for sustained release of buprenorphine

The present invention provides compositions, methods, and kits for treatment of opiate addiction and pain. The invention provides a biocompatible nonerodible polymeric device which releases buprenorphine continuously with generally linear release kinetics for extended periods of time.
Titan Pharmaceuticals, Inc.

April variants

The present invention provides a variant proliferation-inducing ligand (april), which has a higher binding affinity to bcma than wild-type april; and/or altered binding kinetics compared with wild-type april, and/or a higher bcma:taci (transmembrane activator and calcium modulator and cyclophilin ligand interactor) binding ratio than wild-type april and which comprises mutations at one or more of the following positions: a125, v174, t175, m200, p201, s202, h203, d205 and r206.. .
Ucl Business Plc

Pharmacokinetics of s-adenosylmethionine formulations

Compositions and methods to improve the pharmacokinetic profile of s-adenosylmethionine (same) are provided, as are methods of treating various disorders using same formulations with improved pharmacokinetic profiles. More specifically, the invention is directed to methods of treating a disease or disorder in a subject and/or improving the nutritional status of a subject by administering formulations exhibiting improved pharmacokinetic profiles of exogenous same.
Methylation Sciences International Srl

Compositions and methods for inhibiting cytochrome p450

Methods of inhibiting cytochrome p450 enzymes are provided that can be used for improving the treatment of diseases by preventing degradation of drugs or other molecules by cytochrome p450. Pharmaceutical compositions are provided that can act as boosters to improve the pharmacokinetics, enhance the bioavailability, and enhance the therapeutic effect of drugs that undergo in vivo degradation by cytochrome p450 enzymes..
Sequoia Pharmaceuticals, Inc.

Uniform, high basis weight nanofiber fabrics for medical applications

Described herein are devices, compositions and methods relating to the production of high basis weight, non-woven nanofiber polymer fabrics. In certain embodiments, described herein are modifications to free-surface, needle-less or nozzle-less electrospinning devices that permit the production of such high basis weight, non-woven nanofiber polymer fabrics.
University Of Washington

In vitro pharmacokinetics/pharmacodynamics bellows perfusion system for enhancing effectiveness of cancer chemotherapy

Provided herein is a continuous cell perfusion model system that provides useful pharmacokinetic and pharmacodynamic information on the application of new drugs or combinations of various agents in vitro to human cancer cell lines. Also provided are methods of using this system to individualize cancer treatment..

Metal hydride alloys with improved rate performance

Methods of preparing improved metal hydride alloy materials are provided. The alloys include a mixture of at least four of vanadium, titanium, nickel, chromium, and iron.
California Institute Of Technology

Multimeric complexes with improved in vivo stability, pharmacokinetics and efficacy

The present invention concerns multimeric complexes based on antibody fusion proteins comprising an ad moiety attached to the c-terminal end of each antibody light chain. The complexes further comprise effector moities attached to ddd moieties.
Ibc Pharmaceuticals, Inc.

Infusion pump drug delivery profiles, systems, and methods

Embodiments relate generally to drug delivery infusion profiles that can be transferred and executed on infusion pumps without the need for loading new firmware. Particularly, embodiments relate to integrating and/or editing delivery profiles for execution infusion systems.
Smiths Medical Asd, Inc.

Poly(vinyl benzoate) nanoparticles for molecular delivery

The present invention comprises poly(vinyl benzoate) nanoparticle suspensions as molecular carriers. These nanoparticles can be formed by nanoprecipitation of poly(vinyl benzoate) in water using pluronic f68 as surfactant, to create spherical nanostructures measuring about 200-250 nm in diameter which are stable in phosphate buffer and blood serum, and only slowly degrade in the presence of esterases.
University Of South Florida

Enhancing the physical properties of semi-crystalline polymers via solid-state shear pulverization

Solid-state shear pulverization of semi-crystalline polymers and copolymers thereof and related methods for enhanced crystallization kinetics and physical/mechanical properties.. .

Paired laser and electrokinetic separation, manipulation, and analysis device

The combined value of integrating optical forces and electrokinetics allows for the pooled separation vectors of each to be applied, providing for separation based on combinations of features such as size, shape, refractive index, charge, charge distribution, charge mobility, permittivity, and deformability. The interplay of these separation vectors allow for the selective manipulation of analytes with a finer degree of variation.
The Government Of The United States Of America, As Represented By The Secretary Of The Navy

Catalytic effects of oxygen carrier based chemicl-looping reforming of ch4 with co2

The invention relates to ceo2 and la2o3 for catalyzing fe2o3—al2o3 based chemical-looping reforming of ch4 with co2 (cl-drm). The reaction performance of all the composite oxygen carriers was evaluated in a fixed-bed reactor at atmospheric pressure condition.
University Of Wyoming

All natural, non-toxic sublingual drug delievery systems

All natural non-toxic sublingual delivery systems improve absorption and onset profiles for numerous actives, along with bioavailability and pharmacokinetics results that are better than expected for families of moieties compounds and legacy-patented formulations.. .
Scilabs Pharmaceuticals

Particle based immunoassay with alternating current electrokinetics

Disclosed are methods, devices and systems of an immunoassay using an alternate current electrokinetic platform. Also disclosed are methods of separating and detecting analytes from a sample using the disclosed methods..
Biological Dynamics, Inc.

Parenteral formulations of dopamine agonists

This invention relates to stable pharmaceutical compositions for parenteral administration comprising dopamine agonists and peripheral acting agents useful for treatment of metabolic disorders or key elements thereof. The parenteral dosage forms exhibit long stable shelf life and distinct pharmacokinetics..
Veroscience Llc

Process for dyeing keratin materials using powder from indigo-producing plants and alkaline agent(s)

The invention relates (i) to a process for dyeing keratin materials, in particular keratin fibres, preferably human keratin fibres such as the hair, using i) indigo-producing plant powder, ii) at least one alkaline agent as a post-treatment, preferably an alkali metal or alkaline-earth metal (bi) carbonate and iii) optionally a chemical oxidizing agent such as hydrogen peroxide or a hydrogen peroxide-generating system in co-treatment with i), and it being understood that the composition comprising the alkaline agent(s) is at a ph inclusively between 7.5 and 11.5; and (ii) to the use iii) of alkaline agent(s) for fixing the blue colour of and/or for improving the dyeing kinetics of keratin materials dyed with indigo.. .
L'oreal

Pharmacokinetics of iontophoretic sumatriptan administration

Improved pharmacokinetic profiles for the iontophoretic delivery of sumatriptan are described.. .
Teva Pharmaceuticals International Gmbh

Sphingosine kinase type 1 inhibitors and uses thereof

Provided are inhibitors of sphingosine kinase type i that are useful in a number of applications, indications and diseases, as well as for monitoring pharmacokinetics and patient management. These compounds are applicable to treating tumors of the central nervous system, such as glioblastoma multiforme (gbm)..
Virginia Commonwealth University

Yeast strains for producing first-generation ethanol

The present invention concerns yeast strains that have improved properties relative to the specialised strains that are used in the production of first-generation ethanol. In particular, the strains of the invention have an increased ethanol yield, a lower production of glycerol and ethanol production kinetics that are similar or slightly slower than standard strain d1b.
Lesaffre Et Compagnie

Pegylated drug-linkers for improved ligand-drug conjugate pharmacokinetics

The present invention provides ligand-drug conjugates comprising a peg unit in a parallel orientation to the drug unit. The invention provides inter alia, ligand-drug conjugates (ldcs), methods of preparing and using them, and intermediates thereof.
Seattle Genetics, Inc.

Controlled release and taste masking oral pharmaceutical composition

Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. A structure formed by successive amphiphilic, lipophilic or inert matrices and finally inglobated or dispersed in hydrophilic matrices.
Cosmo Technologies Limited

High performance knee prostheses

Knee prostheses that more faithfully replicate the structure and function of the human knee joint in order to provide, among other benefits: greater flexion of the knee in a more natural way by promoting or accommodating internal tibial rotation, replication of the natural screw home mechanism, and controlled articulation of the tibia and femur respective to each other in a natural way. Such prostheses may include an insert component disposed between a femoral component and a tibial component, the insert component featuring, among other things, a reversely contoured posterolateral bearing surface that helps impart internal rotation to the tibia as the knee flexes.
The Trustees Of The University Of Pennsylvania

Population pharmacokinetics tools and uses thereof

The present invention is directed to computer based pharmacokinetics systems, such as. Web-based pharmacokinetics systems, and their use to predict a dose and a dosing interval for a patient in need of a clotting factor therapy..
Biogen Ma Inc.

Solid form of abiraterone acetate

Combinations of (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-yl acetate (abiraterone acetate) with acidic substances such as citric acid, ascorbic acid, methyl-4-hydroxy benzoate, saccharin, vanillic acid, adipic acid, maleic acid, malic acid, tartaric acidare useful as pharmaceutical preparations and show improved properties such as aqueous solubility and dissolution kinetics, especially in the form of cocrystals or their combination with a suitable acid.. .
Basf Se

Method of making modified activated carbon

An activated carbon substrate which is pre-treated to make an exposed surface of the activated carbon substrate substantially hydrophilic, coated with a carbon precursor to form a coated activated carbon, and then the coated activated carbon substrate is heated to carbonize the carbon precursor to from the modified activated carbon. The modified activated carbon comprises a uniform porous carbon membrane formed on an exposed surface of the activated carbon substrate.
Philip Morris Usa Inc.

Aryl linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug

The present invention relates to aryl linked imidazole and triazole derivatives, compositions comprising said compounds, alone or in combination with other drugs, and methods of using the compounds for improving the pharmacokinetics of a drug. The compounds of the invention are useful in human and veterinary medicine for inhibiting cyp3a4 and for improving the pharmacokinetics of a therapeutic compound that is metabolized by cyp3a4..
Merck Sharp & Dohme Corp.

Piperidine or piperazine linked imidazole and triazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug

The present invention relates to piperidine or piperazine linked imidazole and triazole derivatives, compositions comprising said compounds, alone or in combination with other drugs, and methods of using the compounds for improving the pharmacokinetics of a drug. The compounds of the invention are useful in human and veterinary medicine for inhibiting cyp3a4 and for improving the pharmacokinetics of a therapeutic compound that is metabolized by cyp3a4..
Merck Sharp & Dohme Corp.

Methods for determining differences in alpha-4 integrin activity by correlating differences in svcam and/or smadcam levels

Provided herein is a method of monitoring the change of the alpha-4 integrin activities in an individual by correlating with the soluble vascular cell adhesion molecule (svcam) and/or soluble mucosal addressin cell adhesion molecule (smadcam) levels. Particularly, this method can be used, for example, to evaluate the pharmacokinetics and pharmacodynamics (pk/pd) of an alpha-4 integrin inhibitor used to treat a disease associated with pathological or chronic inflammation..
Biogen Inc.

Power generation systems and methods regarding same

A solid fuel power source that provides at least one of thermal and electrical power such as direct electricity or thermal to electricity is further provided that powers a power system comprising (i) at least one reaction cell for the catalysis of atomic hydrogen to form hydrinos, (ii) a chemical fuel mixture comprising at least two components chosen from: a source of h20 catalyst or h20 catalyst; a source of atomic hydrogen or atomic hydrogen; reactants to form the source of h20 catalyst or h20 catalyst and a source of atomic hydrogen or atomic hydrogen; one or more reactants to initiate the catalysis of atomic hydrogen; and a material to cause the solid fuel to be highly conductive, (iii) at least one set of electrodes that confine the fuel and an electrical power source that provides a short burst of low-voltage, high-current electrical energy to initiate rapid kinetics of the hydrino reaction and an energy gain due to forming hydrinos, (iv) a product recovery systems such as a condenser (v) a reloading system, (vi) at least one of hydration, thermal, chemical, and electrochemical systems to regenerate the fuel from the reaction products, (vii) a heat sink that accepts the heat from the power-producing reactions, (viii) a power conversion system that may comprise a direct plasma to electric converter such as a plasmadynamic converter, magnetohydrodynamic converter, electromagnetic direct (crossed field or drift) converter, direct converter, and charge drift converter or a thermal to electric power converter such as a rankine or brayton-type power plant.. .
Brilliant Light Power, Inc.

Aerosol fluoroquinolone formulations for improved pharmacokinetics

The present invention relates to the field of antimicrobial agents. In particular, the present invention relates to the use of aerosolized fluoroquinolones formulated with divalent or trivalent cations and having improved pulmonary availability for the treatment and management of bacterial infections of the lung and upper respiratory tract..
Raptor Pharmaceuticals Inc.

Method for determining interaction kinetics with rapid dissociation

The invention relates to a method for determining interaction kinetics for an analyte. The method comprises first contacting a solution containing the analyte with immobilized ligand, or analogue thereof, immobilized on an optical sensor surface; monitoring the binding of the analyte to the immobilized ligand or analogue, wherein the binding is measured as a resulting change in a property of the surface; and automatically determining the interaction kinetics, which determining step includes first defining parts of the dissociation phase that contains kinetic information for fitting.
Ge Healthcare Bio-sciences Ab

Fuel injector

A fuel injector includes fixed metal components, in particular an injector body, a solenoid actuator equipped with a retaining spring that holds a control valve stem, a control valve body including a seat for the control valve stem, a spacer between the body of the control valve and an injection nozzle, a control chamber, and an injection needle seat. The fuel injector also includes movable metal components, in particular the control valve stem and an armature thereof and an injection needle.
Delphi International Operations Luxembourg S.À R.l.

Composition of excipients and pharmaceutical forms with sustained release and increased bioavailability of antibacterial drugs, anticoccidial drugs and other drugs for commercial poultry and pigs

The invention relates to a composition of excipients and pharmaceutical forms of sustained release and increased drug bioavailability for poultry and pigs and to a method of producing the same, said composition comprises: pharmaceutically active agents, bioavailability promoting agents, polymers for prolonged release of the drug, colouring agents, and flavouring agents. The composition of excipients and pharmaceutical forms of the invention optimizes the dosing of the drug dosage and generates resistant strains of bacteria by optimizing the ratio between pharmacokinetics/pharmacodynamics of drugs.
Universidad Nacional AutÓnoma De MÉxico

Assays for measuring binding kinetics and binding capacity of acceptors for lipophilic or amphilphilic molecules

Aspects of the invention relate to methods for measuring the binding constant of a lipophilic or amphiphilic molecule acceptor for a lipophilic or amphiphilic molecule. Methods involve rapid, cell-free competition assays including a labeled lipophilic or amphiphilic molecule and nanoparticle..
Northwestern University



Kinetics topics:
  • Medical Device
  • Polypeptide
  • Nucleic Acid
  • Nucleic Acids
  • Specificity
  • Surfactant
  • Enhancement
  • Scattering
  • Electrolyte
  • Conductive Elements
  • Amplification
  • Red Blood Cell
  • Red Blood Cells
  • Antibodies
  • Luciferase


  • Follow us on Twitter
    twitter icon@FreshPatents

    ###

    This listing is a sample listing of patent applications related to Kinetics for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Kinetics with additional patents listed. Browse our RSS directory or Search for other possible listings.


    1.3202

    file did exist - 2292

    0 - 1 - 51