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Kinetic patents



      

This page is updated frequently with new Kinetic-related patent applications.




Date/App# patent app List of recent Kinetic-related patents
07/21/16
20160211981 
 System and  multicast over highly mobile mesh networks patent thumbnailSystem and multicast over highly mobile mesh networks
Systems, devices, and methodology for removing echo and reducing congestion in multicast (broadcast) over a dynamic self-healing mobile mesh network, by use of discrete embedded computers synchronously tracking mesh connections and link quality across multiple rf connections, keeping multicast both efficient and effective in a highly kinetic, ever changing, mesh topology.. .
Rajant Corporation


07/21/16
20160211445 
 Method for making mram with small dimension and high qulity patent thumbnailMethod for making mram with small dimension and high qulity
This invention is about a method to make an mram element with small dimension, by making an mtj as close as possible to the via, ideally aligning the mtj and the via in a direction perpendicular to the wafer surface, for making the mram element dimension as small as possible. The invention provides a process scheme to flatten the interface of bottom electrode during film deposition, which ensures a good deposition of atomically smooth mtj multilayer as close as possible to an associated via which otherwise might be atomically rough.
T3memory, Inc.


07/21/16
20160210436 
 System and  ranking options for medical treatments patent thumbnailSystem and ranking options for medical treatments
A computer system, computer program product and method for determining a probability of attaining a pk-pd target associated with efficacy for a patient that includes a processor obtaining information identifying an infection and based on the information, generating and displaying, by the processor, a list comprising one or more pathogens consistent with the information, the processor then obtaining a first indication designating at least one pathogen from the list comprising one or more pathogens and based on at the obtaining of the least one pathogen, generating a list comprising one or more drug therapies utilized to treat the at least one pathogen. The method also includes the processor obtaining, descriptive information relating to a patient and based on the one or more drug therapies, selecting a pharmacokinetic model and the processor applying the pharmacokinetic model and utilizing the information relating to the patient to determine, for each of the one or more drug therapies, a probability of attaining a pk-pd target associated with efficacy for the patient with the infection..
Institute For Clinical Pharmacodynamics


07/21/16
20160210401 
 Method and system for selecting drug on basis of individual protein damage information for preventing side effects of drug patent thumbnailMethod and system for selecting drug on basis of individual protein damage information for preventing side effects of drug
The present invention relates to a method and a system for selecting a drug customized on the basis of individual protein information by using individual genome sequences. The method and the system of the present invention can predict the individual side effects or danger of a certain drug by analyzing the sequence of the exon region of a gene encoding various proteins involved in the pharmacokinetics or pharmacodynamics of a predetermined drug or drug group, and have high reliability and are widely applicable and universal..
Cipherome, Inc.


07/21/16
20160209403 
 Componential analyzer, drug efficacy analyzer, and analysis method patent thumbnailComponential analyzer, drug efficacy analyzer, and analysis method
Application of the present invention enables quantification of fractions of candidate pharmaceutical compounds (a parent compound and its metabolites), one excreted to the basolateral (basal/basolateral)-side via transporters and by diffusion, one excreted to the lumen (apical)-side, and one remained in the cells. This enables determination of the total amount of the administered candidate pharmaceutical compounds and the distribution ratio of the fractions.
Hitachi High-technologies Corporation


07/21/16
20160208686 
 Energy storage and conversion in free-piston combustion engines patent thumbnailEnergy storage and conversion in free-piston combustion engines
Various embodiments of the present disclosure are directed towards free-piston combustion engines. As described herein, a driver section may be provided in a free-piston combustion engine for storing energy during an expansion stroke.
Etagen, Inc.


07/21/16
20160208233 
 Evolved sortases and use thereof patent thumbnailEvolved sortases and use thereof
Evolved sortases exhibiting enhanced reaction kinetics and/or altered substrate preferences are provided herein, for example evolved sortases that bind recognitions motifs comprising a laxt or lpxs sequence. Also provided are methods (e.g., orthogonal transpeptidation and diagnostics methods) for using such sortases.
President And Fellows Of Harvard College


07/21/16
20160207902 
 Tocopherol and tocopheryl quinone derivatives as correctors of lysosomal storage disorders patent thumbnailTocopherol and tocopheryl quinone derivatives as correctors of lysosomal storage disorders
The subject invention relates to improved tocopheryl quinone derivatives and tocopherol derivatives having improved pharmacokinetics in vivo that can, in some embodiments, be useful in the treatment of lysosomal storage disorders, restoration of normal mitochondrial atp production, modulation of intracellular calcium ion concentration and other treatments or therapies. The tocopheryl quinone derivatives and tocopherol derivatives have side chains that have terminally halogenated carbon atoms..
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv


07/21/16
20160207883 
 Novel aromatic compound and use thereof patent thumbnailNovel aromatic compound and use thereof
[wherein each substituent is as defined in the description], has low toxicity, shows good pharmacokinetics, has an action to promote bone formation, and is useful for the prophylaxis or to treatment of metabolic bone diseases (osteoporosis, fibrous osteitis (hyperparathyroidism), osteomalacia, paget's disease that influences the systemic bone metabolism parameter etc.) associated with a decrease in the bone formation ability as compared to the bone resorption capacity.. .

07/21/16
20160207600 
 Hydro-compressed gas powered marine engine, marine vessels using such engine and method patent thumbnailHydro-compressed gas powered marine engine, marine vessels using such engine and method
A marine vessel is propelled through water using a hydro-compress gas powered engine including a chamber having a hydropower motor in an upper section and a compressed gas motor in a lower section. In a first cycle of the engine water is introduced into the hydropower motor that driving a drives a crankshaft using the kinetic energy of falling water.

07/21/16
20160206912 

Kinetic resistance apparatus


A portable and kinetic motion resistance upper body invention that can be used for a variety of exercises. This invention combines dial tension adjustment clutch sheaves, a variable linear tract bearing and a one piece resistance shock-cord, together these core components achieve a unique minimal impact work-out.

07/14/16
20160201860 

Self-powered wearable luminous device


A self-powered wearable luminous device belongs to a technical field of the self-powered wearable device which is capable of achieving self-powering by collecting kinetic energy of the human body. A power generation module, an electronic component and a luminous component are connected with each other via wires and are installed within a wearable unit.

07/14/16
20160201664 

Long-stroke pumping unit


A long-stroke pumping unit includes: a tower; a counterweight assembly movable along the tower; a drum connected to an upper end of the tower and rotatable relative thereto; a belt having a first end connected to the counterweight assembly, extending over the drum, and having a second end connectable to a rod string; a prime mover for reciprocating the counterweight assembly along the tower; a sensor for detecting sudden acceleration of the counterweight assembly due to failure of the rod string; at least one of: a braking system for halting free-fall of the counterweight assembly; and an arrestor system for absorbing kinetic energy of the falling counterweight assembly; and a controller in communication with the sensor and operable to activate the braking or arrestor system in response to detection of the sudden acceleration.. .
Weatherford Technology Holdings, Llc


07/14/16
20160201647 

Translating foil system for harvesting kinetic energy from wind and flowing water


Consistent kinetic energy is harvested from wind and from flowing water in streams, rivers and tidal flows using a translating large sail, foil or wing which is permitted to translate in one direction, followed by translating in the opposite direction while pushing or pulling a cable, rod, or tether which in turn turns a pulley, wheel or other device from which traditional sources of power can be generated. The pulley wheel can be used to generate electricity, create hydrogen from water by electrolysis, compress air for transmission or storage, charge batteries, or perform work such as pumping water, heating water, moving objects, etc..

07/14/16
20160201639 

Onshore hydroelectric power generation device


An onshore hydroelectric power generation device is disposed above a flow to obtain and convert the energy of flow into electricity, comprising a body unit, a water wheel unit, a mobile energy transmitting unit, and an electricity power generating unit. The kinetic energy of the flow is obtained by the water wheel unit, and is transmitted to the power generation unit adapted to the height of water level by the mobile energy transmitting unit..
Tzoo Ying Enterprise Co., Ltd.


07/14/16
20160201423 

Blowout preventer stack and supply system


The invention relates to a blowout preventer stack comprising blowout preventer stack components. A part of the blowout preventer stack components has a blowout preventer with an electric blowout preventer drive means for operating the blowout preventer.

07/14/16
20160201409 

Method for putting together of a drilling device and drilling device


A method for assembling a drilling device. A first drilling member is power transittingly, coupled with a second drilling member during drilling for rotational, feeding and/or hammering motion, and removably coupled to remove the first drilling member from a hole.
Oy Atlas Copco Rotex Ab


07/14/16
20160200968 

Water treatment


The present invention relates to a method of treating aqueous fluid and apparatus therefor. The method comprises adding an organic compound to a mass of aqueous fluid comprising at least one kinetic hydrate inhibitor (khi).
Hydrafact Limited


07/14/16
20160200730 

Polyfluorinated compounds acting as bruton tyrosine kinase inhibitors


Described herein is a novel series of multi-fluoro-substituted pyrazolopyrimidine compounds or salts thereof. These compounds are bruton's tyrosine kinase (btk) inhibitors.
Zhejiang Dtrm Biopharma Co. Ltd.


07/14/16
20160200458 

Converging/diverging magnetic nozzle


A magnetic nozzle having a converging/diverging contour shape that converts the thermal energy of a propellant into directed kinetic energy, but uses magnetic fields instead of a physical boundary to direct the flow of particles.. .
The Regents Of The University Of Michigan


07/14/16
20160200005 

Method of operating a temperature-controlled thermokinetic mixer for regenerating vulcanized rubber


A method of operating a temperature-controlled k-mixer for thermally and kinetically regenerating vulcanized crumb rubber is provided. The k-mixer includes a chamber and a shaft provided with a plurality of blades.
Phoenix Innovation Technology Inc.


07/14/16
20160199392 

Method for individualized drug therapy


Methods for individualized therapy of arthritic pain using a non-steroidal anti-inflammatory drug (nsaid). Said methods comprise basing nsaid dose on each patient's pharmacokinetic and pharmacodynamic response to said nsaid..
Autotelic Llc


07/14/16
20160199354 

Methods for olmesartan dosing by auc


Methods for antihypertensive drug dosing by pharmacokinetic parameter determination. In one embodiment, the antihypertensive drug is olmesartan and the pharmacokinetic parameter is auc.
Autotelic Llc


07/14/16
20160198989 

Implantable devices and methods for the evaluation of active agents


Devices for the local delivery of microdose amounts of one or more active agents, alone or in combination, in one or more dosages, to selected tissue of a patient are described. The devices generally include multiple microwells arranged on or within a support structure.
Kibur Medical, Inc.


07/07/16
20160195518 

Experimental methods for conducting competitive binding assays


The present disclosure is directed toward improved methods of conducting a competitive binding assay or experiment. The methodology includes utilizing either a positive control, a negative control, or both in order to scale experimentation results to results that can be utilized to obtain a precise measurement of the kinetic rate constant (the off rate denoted as koff) describing the dissociation of a non-covalent complex such as an antibody antigen complex, receptor ligand complex, etc..
Sapidyne Instruments Inc.


07/07/16
20160194879 

Automatic retractable downspout system


An automatic retractable gutter assembly (10) dispenses rainwater collected in a gutter (14). A short down-tube (26) is attached to the gutter (14).

07/07/16
20160194702 

Device, system, and depositing processed immiscible-fluid-discrete-volumes


Various embodiments relate to systems and/or methods for sample preparation that can be used for biochemical and/or molecular biology procedures involving small volumes, for example, micro volumes or smaller. Methods and systems that can reduce sample size requirements and increase the number of samples on a substrate are provided.
Applied Biosystems, Llc


07/07/16
20160194574 

Segmented copolymer compositions and coatings incorporating these compositions


Some variations provide a segmented copolymer composition comprising: fluoropolymer first soft segments that are (α,ω)-hydroxyl-terminated and/or (α,ω)-amine-terminated; polyester or polyether second soft segments that are (α,ω)-hydroxyl-terminated and/or (α,ω)-amine-terminated; isocyanate species possessing an isocyanate functionality of 2 or greater; and polyol or polyamine chain extenders or crosslinkers, wherein the molar ratio of the second soft segments to the first soft segments is less than 2.0. Exemplary segmented copolymers are disclosed.
Hrl Laboratories, Llc


07/07/16
20160194437 

New formulation methodology for distortional thermosets


And a diamine curing agent. The resultant distortional thermoset compositions possess superior out-life requirements and advantageous reaction kinetics for preparing prepreg compositions and materials..

07/07/16
20160194370 

Fusion protein of therapeutic polypeptide with improved pharmacokinetic profile and use therof


The present invention provides a fusion protein comprising a therapeutic polypeptide fused to one or more flexible unstructured polypeptides and a trimeric scaffold protein. The flexible unstructured polypeptide sequence within the fusion protein is exhibited as one or more pcloud sequences derived from human fibrinogen alpha chain, and may be flanked by a proteinous connecting moiety of human origin.
Beijing Anxinhuaide Biotech. Co., Ltd.


07/07/16
20160193734 

Kinetic and dimensional optimization for a tendon-driven gripper


A tendon-driven robotic gripper is disclosed for performing fingertip and enveloping grasps. One embodiment comprises two fingers, each with two links, and is actuated using a single active tendon.
Willow Garage, Inc.


07/07/16
20160193604 

Systems for operating electrokinetic devices


A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device.
Berkeley Lights, Inc.


07/07/16
20160193372 

Methods of identifying surrogate imaging agents for alpha emitter radiopharmaceuticals and their use in treatment of disease


In accordance with one or more embodiments, the present invention provides a series of identified radiopharmaceuticals herein termed “imaging surrogates” whose pharmacokinetic behavior matches that of the alpharpt for several alpharpts currently under investigation as cancer therapeutics. Methods for identifying imaging surrogates are also provided.
The Johns Hopkins University


07/07/16
20160193354 

Antisense oligonucleotides with improved pharmacokinetic properties


In addition, the pharmaceutical composition or pharmaceutical kit or conjugate can be used for the treatment of a disease or disorder that can be at least in part alleviated by therapy, wherein the disease or disorder is selected from the group consisting of bacterial infections, viral infections, cancer, metabolic diseases and immunological disorders and preferably cancer.. .

07/07/16
20160193351 

Conjugate based systems for controlled drug delivery


Conjugates which comprise a drug and a ligand which includes a first saccharide; wherein the conjugate is characterized in that, when the conjugate is administered to a mammal, at least one pharmacokinetic or pharmacodynamic property of the conjugate is sensitive to serum concentration of a second saccharide. Exemplary conjugates and sustained release formulations are provided in addition to methods of use and preparation..
Smartcells, Inc.


07/07/16
20160193151 

Dosage form incorporating an amorphous drug solid solution


The dissolution of active pharmaceutical ingredients in polymeric melts plays an important role in the manufacturing of drugs that use polymers as excipients. The dissolution kinetics is essential for designing the processing equipment, describing the operating conditions, and defining material properties, for example, the appropriate api-polymer(s) pair.

07/07/16
20160192872 

Using kinetic cyclic voltammetry to evaluate analyte kinetics and concentrations


Materials and methods for using kinetic cyclic voltammetry to measure analyte levels and assess analyte kinetics.. .
Mayo Foundation For Medical Education And Research


06/30/16
20160190866 

Power control device


A power control device for controlling electrical power transferred between an ac power grid and a load or between the ac power grid and an auxiliary power source. For example, the power control device may be configured to monitor an electrical characteristic of electrical energy supplied by the ac power grid to the load and to adjust a consumption of the electrical energy by the load when the electrical characteristic indicates that the ac power grid is no longer in a state of balance.

06/30/16
20160186782 

Ejector


In an ejector, a substantially conical passage formation member is disposed in the interior of a body forming a space therein to define a nozzle passage functioning as a nozzle, a mixing passage in which an ejection refrigerant ejected from the nozzle passage and a suction refrigerant drawn from a suction passage are mixed together, and a diffuser passage that converts a kinetic energy of the refrigerant that has flowed out of the mixing passage into a pressure energy, between an inner peripheral surface of the body and the passage formation member. The passage formation member is configured so that a spread angle of a portion forming an outlet side of the nozzle passage is smaller than a spread angle of a portion forming an inlet side of the nozzle passage in a cross-section parallel to an axial direction of the passage formation member..

06/30/16
20160186719 

Psp wind-powered generator comprising blades at dihedral angles


The invention relates to a wind-powered generator comprising blades at dihedral angles (psp), characterised by an aerodynamic, semi-flat blade having, on one if its sides, a bent section measuring approximately a quarter of the total width of the blade and forming a dihedral angle of less than 30°, the interior space of which captures the kinetic power of the wind impacting on the blade, thereby generating a powerful rotary movement in that direction. The blades form a diametrical set of two blades generating a strong and effective rotary movement at a 90° angle to the linear movement of the wind.

06/30/16
20160185874 

Serum albumin binding peptides for tumor targeting


Peptide ligands having affinity for serum albumin are useful for tumor targeting. Conjugate molecules comprising a serum albumin binding peptide fused to a biologically active molecule demonstrate modified pharmacokinetic properties as compared with the biologically active molecule alone, including tissue (e.g., tumor) uptake, infiltration, and diffusion..

06/30/16
20160185752 

Piperidine and azepine derivatives as prokineticin receptor modulators


The present invention provides compounds of formula (i) and pharmaceutically acceptable salts thereof (formula (i)) in which m, x, r1, r2, r3 and r5 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.. .

06/30/16
20160185108 

Liquid ejection control device, liquid ejection system, and control method


In a liquid ejection control device, an operation unit includes an energy dial for inputting an energy instructing value related to kinetic energy of a pulsed liquid jet ejected from a liquid ejection device, and a repetitive frequency dial for inputting a repetitive frequency instructing value related to the number of times ejection of the pulsed liquid occurs per unit time. In addition, a controller includes a rising frequency setting section that sets rising frequency as a rising index value related to rising of a drive voltage waveform such that the kinetic energy becomes the energy instructing value, based on voltage magnitude of the drive voltage waveform and the repetitive frequency instructing value..

06/30/16
20160185106 

Liquid ejection control device, liquid ejection system, and control method


In a liquid ejection control device, an operation unit includes an energy dial for inputting an energy instructing value related to kinetic energy of a pulsed liquid jet ejected from a liquid ejection device, and a repetitive frequency dial for inputting a repetitive frequency instructing value related to the number of times ejection of the pulsed liquid occurs per unit time. In addition, a controller includes a voltage magnitude setting section that sets voltage magnitude of the drive voltage waveform such that the kinetic energy becomes the energy instructing value, based on a rising index value related to rising of the drive voltage waveform and the repetitive frequency instructing value..

06/30/16
20160185081 

Kinetically limited nano-scale diffusion bond structures and methods


Bulk materials having a kinetically limited nano-scale diffusion bond is provided. The bulk materials having a kinetically limited nano-scale diffusion bond includes transparent material, absorbent opaque material and a diffusion bond.

06/30/16
20160184821 

Lateral/vertical transistor structures and process of making and using same


A microfluidic device can include a base an outer surface of which forms one or more enclosures for containing a fluidic medium. The base can include an array of individually controllable transistor structures each of which can comprise both a lateral transistor and a vertical transistor.

06/30/16
20160184345 

Polymer-conjugated metap2 inhibitors, and therapeutic methods of use thereof


One aspect of the invention provides polymer conjugated metap2 inhibitors. While not being bound by any particular theory, it is believed that coupling the metap2 inhibitory core via the linkers described herein provides compounds with superior efficacy to the parent small molecules and superior pharmacokinetic profiles.

06/30/16
20160184082 

Bionic muscle


The present invention provides an electromagnetic device comprising: a power circuit, and a contact initiated electro-magnet having an electrical coil in operable connection with the power circuit, wherein one end of the electrical coil is directly connected to the power circuit and the other is connected to the magnetic core of the electromagnet such that, in use, the magnetic core performs the dual purposes of (i) focusing the electromagnetic field created by the coil and (ii) forms part of the electrical circuit that energizes the magnetic core of the electromagnet. Multiple electromagnetic devices may be combined to form a kinetic device capable of creating an electrically-based movement device that mimics the form and function of the skeletal muscle through the use of multiple contact initiated electromagnets held within elastic tubes..

06/23/16
20160178289 

Kinetic heat-sink with interdigitated heat-transfer fins


A kinetic heat sink has a stationary portion with a first heat-conducting surface and a second heat-conducting surface to conduct heat therebetween. To cool heat generating devices devices, the stationary portion is mountable to a heat-generating component and has a first plurality of fins extending therefrom.

06/23/16
20160177925 

Method for controlling wind power plants


A method for supplying electrical energy into an electrical supply network by means of a wind power plant or wind farm, where the wind power plant or wind farm converts kinetic energy from wind with variable speed to electrical energy, the wind power plant or wind farm is prepared for supplying active power and reactive power and the reactive power to be fed in is set based on the wind velocity.. .

06/23/16
20160177912 

Reciprocating motion energy conversion apparatus


A reciprocating motion energy conversion apparatus is adapted to capture kinetic energy of wind, waves, or other reciprocating or turbulent motion in order to generate electricity. A rolling shaft rests on a shaft guide frame, with the rolling shaft being coupled to the input shaft of at least one electric generator.

06/23/16
20160177520 

Working device


The invention relates to a working device for a ground-processing device having a milling drum with a milling drum tube on whose surface working tools are mounted in a projecting manner and are intended to come into contact with the material to be milled during the milling process, wherein the working device has a powertrain for driving the milling drum. In order to improve the running smoothness of a ground-processing machine, provision is made according to the invention for at least one load weight to be arranged, preferably interchangeably, on the powertrain and/or on the milling drum to increase the kinetic energy..

06/23/16
20160177384 

Sequencing systems with two slow-step polymerase enzymes


Systems for nucleotide sequencing comprising producing polymerase reactions that exhibit two kinetically observable steps within an observable phase of the polymerase reaction. Two slow step systems can be produced, for example, by selecting the appropriate polymerase enzyme, polymerase reaction conditions including cofactors, and polymerase reaction substrates including the primed template and nucleotides..

06/23/16
20160177382 

Devices and methods for controlling reversible chemical reactions at solid-liquid interfaces by rapid preconcentration and phase replacement


Devices and methods for controlling reversible chemical reactions at solid-liquid interfaces are disclosed. In particular, the invention relates to a method of increasing reaction rates by concentrating a target molecule in a liquid phase in the region of a reactant or ligand immobilized on a solid followed by removal of the liquid phase and replacement with an immiscible phase, such as an immiscible gas or liquid to impede the reverse reaction.

06/23/16
20160176899 

Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2h)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same


Co-crystals of formula i compounds and their pharmaceutical compositions are novel therapeutics for the treatment of diseases, such as human immunodeficiency virus (hiv) infection, hepatitis b virus (hbv) infection, hepatitis c virus (hcv) infection and cancer. The co-crystal are more stable to oxidation and aqueous degradation, have a better pharmacokinetic profile and superior biological activity than the corresponding tosylate salt form of formula i compound..

06/23/16
20160174534 

Genetically modified rat models for pharmacokinetics


The present invention provides a desired rat or a rat cell which contains a predefined, specific and desired alteration rendering the rat or rat cell predisposed to drug transport sensitivity or resistance drug transport resistance or sensitivity. Specifically, the invention pertains to a genetically altered rat, or a rat cell in culture, that is defective in at least one of two alleles of a drug transporter gene such as the slc7a11 (nc_005101.2) gene, the abcb1 (nc_005103.2) gene, etc.

06/16/16
20160173017 

Method for controlling wind turbines


A method for feeding electrical energy into an electrical supply grid by means of a wind turbine or wind farm, where the wind turbine or wind farm converts kinetic energy from wind with variable speed to electrical energy, a wind speed is predicted based on a wind forecast and a reactive power to be fed in is calculated as predicted reactive power based on the predicted wind speed.. .
Wobben Properties Gmbh


06/16/16
20160172955 

Fluid ferfereh


In this device, the nozzles that often used in order to make a linear motion, so they can be helpful in rotating the disc if they are placed at the external ring of disc. In addition, in this case, apart from generating electricity from the discharging fluid of the nozzle by ionization method, the kinetic energy of the discharging fluid can be used for rotating the disc as well..

06/16/16
20160172934 

Contra rotor wind turbine system using a hydraulic power transmission device


The present invention provides a system for an energy efficient contra rotor wind turbines comprises of two dual aerodynamic rotors composed of plurality of either radially extended blades or axially extended helically contoured blades. The blades on the upwind or outer rotor are set to spin in the first direction about the outer shaft, while the blades on the downwind or inner rotor are set to spin in a second direction about the co-axially mounted center shaft.

06/16/16
20160172155 

Device and detecting and generating combined modulated particle wave-fronts


The present disclosure relates to a particle and energy detection system. More particularly, the present disclosure relates to coherent particle generation/detection devices configured to detect a plurality of particles (or energy quanta) which are caused to be combined by superposition upon impacting the detector and imparting a portion of their kinetic energy to the detection process.

06/16/16
20160171183 

Simulation of endogenous and exogenous glucose/insulin/glucagon interplay in type 1 diabetic patients


A simulator for in-silico testing of type 1 diabetes patients uses a model that puts in relation plasma concentrations, i.e., glucose g and insulin /, with glucose fluxes, i.e. Endogenous glucose production (egp), glucose rate of appearance (ra), glucose utilization by the tissues (u), renal extraction (e), and insulin fluxes, i.e., rate of insulin appearance from the subcutaneous tissues (sc) and insulin degradation (d).
University Of Virginia Patent Foundation


06/16/16
20160169914 

Kinetics biomarkers for neurodegeneration


The present invention relates to novel diagnostic, prognostic, predictive and pharmacodynamic properties with regard to amyotrophic lateral sclerosis (als) and/or parkinson's disease (pd) with and without dementia components. The methods described herein will prove very useful in the development of diagnostic as well as treatment strategies for patients with amyotrophic lateral sclerosis (als) and/or parkinson's disease (pd)..
Kinemed, Inc.


06/16/16
20160169565 

Ejector


In an ejector, a passage formation member is disposed inside a body forming a space therein. Provided between an inner peripheral surface of the body and the passage formation member are a nozzle passage functioning as a nozzle, a mixing passage in which an ejection refrigerant ejected from the nozzle passage and a suction refrigerant drawn through a suction passage are mixed together, and a diffuser passage that converts a kinetic energy of the refrigerant that has flowed out of the mixing passage into a pressure energy.
Denso Corporation


06/16/16
20160169323 

Flywheels for energy storage and methods of manufacture thereof


A flywheel for kinetic energy storage and its construction using composite materials. The present invention provides a flywheel assembly having a longitudinal axis and comprising an annular rotor and a rotor support for coupling the rotor to an axial shaft, wherein the rotor comprises fibres in a matrix material, and a ring comprising fibres in a matrix material is mounted on the outer circumference of the rotor support and the rotor is mounted on the outer circumference of the ring, the rotor, rotor support and ring each having longitudinal axes which are coincident with the longitudinal axis of the assembly.
Gkn Hybrid Power Limited


06/16/16
20160169189 

Engine for conversion of thermal energy to kinetic energy


An engine for converting thermal energy to kinetic energy is provided. The engine includes a first zone and a second zone and a movable loop, which extends between the first zone and the second zone.

06/16/16
20160168633 

Apparatus and methods for kinetic analysis and determination of nucleic acid sequences


A system for determining nucleic acid sequences, including (a) an array of nucleic acid features; (b) a fluidic apparatus configured to deliver sequencing reagents, including polymerases and nucleotides, to the array; (c) a detector configured to obtain pre-equilibrium kinetic measurements from the array at a resolution that distinguishes individual nucleic acid features; (d) a control module having instructions for (i) directing the fluidic apparatus to deliver the sequencing reagents to the array, and (ii) directing the detection apparatus to obtain the kinetic measurements; and (e) an analysis module having instructions for (i) processing the kinetic measurements to determine binding of the polymerase molecules to the nucleic acid features at several pre-equilibrium time points, thereby determining a transient state of the polymerase molecules at the nucleic acid features, and (ii) identifying nucleic acid features that correctly incorporate the nucleotide molecules based on the transient state of the polymerase molecules.. .
Illumina, Inc.


06/16/16
20160166695 

Rapid-acting insulin compositions


The invention is a composition of human insulin or insulin analog that includes specific concentrations of citrate, chloride, in some cases including the addition of sodium chloride, zinc and, optionally, magnesium chloride and/or surfactant, and that has faster pharmacokinetic and/or pharmacodynamic action than commercial formulations of existing insulin analog products.. .
Eli Lilly And Company


06/09/16
20160164373 

Automobile roller-type power generating device


An automobile roller-type power generating device installed at the bottom of a vehicle body includes: a roller pivotally coupled to a camshaft and having a notch; a push slider having an arc bottom and installed in the notch of the roller, and the notch being in a shape corresponsive to the push slider and slightly greater than the push slider to allow the push slider to slide up and down; and a power generating mechanism installed above the pushrod. When the motor vehicle moves to roll the roller, the arc bottom presses the ground and slides into the roller to allow the push slider to slide up and down to transmit kinetic energy to the power generating mechanism, and the power generating mechanism converts the kinetic energy into electric energy to achieve the effect of generating power generation and storing electric energy into the battery..

06/09/16
20160163970 

Method for makinga magnetic random access memory element with small dimension and high qulity


This invention is about a method to make an mram element with small dimension, by building an mtj as close as possible to an associated via connecting an associated circuitry in a semiconductor wafer. The invention provides a process scheme to flatten the interface of bottom electrode during film deposition, which ensures a good deposition of atomically smooth mtj multilayer as close as possible to an associated via which otherwise might be atomically rough.
Shanghai Ciyu Information Technologies Co., Ltd


06/09/16
20160161514 

Simultaneous assay of target and target-drug binding


Whole cell, simultaneous target and drug-target assay using differentially labeled antibodies and flow cytometry. First antibody binds to total target and second antibody binds to the drug binding site of the target, thus drug binding will competitively inhibit the second antibody allowing for a competitive inhibition assay of drug-target binding.
Laboratory Corporation Of America Holdings


06/09/16
20160161379 

In situ chemical transformation and ionization of inorganic perchlorates on surfaces


A method for providing in situ chemical transformation and ionization of a portion (e.g., inorganic oxidizer) of a sample via an analyte detection system is disclosed herein. The method includes introducing a gas into an ionization source of the analyte detection system via an inlet.
Smiths Detection Montreal Inc.


06/09/16
20160160978 

Torque converter and hydrokinetic torque coupling device having turbine-piston lockup clutch, and related methods


A hydrodynamic torque coupling device with lockup clutch is provided that includes an impeller, an axially displaceable turbine-piston, and a stop feature. The turbine-piston includes a turbine-piston shell and a turbine-piston flange.
Valeo Embrayages


06/09/16
20160160977 

Torque converter and hydrokinetic torque coupling device having core lockup clutch, and related methods


A hydrokinetic torque converter includes an impeller, an axially displaceable turbine piston, and impeller and turbine-piston lockup clutch core plates. The impeller lockup clutch core plate is situated between the impeller shell and the turbine-piston shell, is connected to an impeller core ring, and has a first surface.
Valeo Embrayages


06/09/16
20160160976 

Hydrokinetic torque coupling device having turbine-piston lockup clutch, and related methods


A hydrokinetic torque coupling device features an impeller, a casing having a first engagement surface, a damper assembly, a turbine-piston including a drive component with a second engagement surface, and a clutch plate having clutch plate engagement surfaces interposed between and axially movable relative to at least one of the first and second clutch plate engagement surfaces. The turbine-piston is axially displaceable relative to the casing to move the second engagement surface axially towards and away from the first engagement surface for positioning the hydrokinetic torque coupling device into and out of a lockup mode in which the first and second engagement surfaces and the clutch plate engagement surfaces frictionally interlock with one another to non-rotatably lock the casing relative to the input part of the damper assembly..
Valeo Embrayages


06/09/16
20160160975 

Torque converter and hydrokinetic torque coupling device having turbine-piston lockup clutch, and related methods


A torque converter is provided that includes an impeller having an impeller shell with a first surface, an axially displaceable turbine-piston hydrodynamically drivable by the impeller and including a turbine-piston shell and a turbine-piston flange with a second surface, and a clutch plate interposed between and axially displaceable relative to at least one of the first and second surfaces. The turbine-piston is axially movable relative to the impeller to move the second surface of the turbine-piston flange towards and away from the first surface for positioning the torque converter into and out of a lockup mode in which the first and second surfaces and the clutch plate surfaces frictionally interlock with one another so that the impeller is mechanically locked to and non-rotatable relative to the turbine-piston..
Valeo Embrayages


06/09/16
20160160974 

Hydrokinetic torque coupling device having turbine-piston lockup clutch, and related methods


A hydrokinetic torque coupling device includes an impeller, a casing having a first engagement surface, a turbine-piston hydrodynamically drivable by the impeller, and a bearing device. The turbine-piston is axially displaceable into and out of a lockup mode.
Valeo Embrayages


06/09/16
20160160973 

Hydrokinetic torque coupling device having turbine-piston lockup clutch, and related methods


A hydrokinetic torque coupling device includes an impeller, a casing having a first engagement surface, a turbine-piston hydrodynamically drivable by the impeller, and a biasing device. The turbine-piston is hydrodynamically drivable by the impeller and includes a turbine-piston shell having a second engagement surface facing the first engagement surface.
Valeo Embrayages


06/09/16
20160160972 

Torque converter and hydrokinetic torque coupling device having turbine-piston lockup clutch with lockup resistance member


A torque converter includes an impeller, a turbine-piston hydrodynamically drivable by the impeller, a stator, and an annular lockup resistance member. The impeller includes an impeller shell.
Valeo Embrayages


06/09/16
20160160971 

Torque converter and hydrokinetic torque coupling device having turbine-piston lockup clutch, and related methods


A hydrokinetic torque coupling device features an impeller including an impeller shell and impeller blades, and a turbine-piston including a turbine-piston shell and turbine blades. The turbine-piston is movable axially toward and away from the impeller shell to position the torque converter (or a hydrokinetic torque coupling device containing the torque converter) into and out of lockup mode..
Valeo Embrayages


06/09/16
20160160826 

High pressure fuel supply pump with electromagnetic suction valve


To reduce collision noise created by the operation of an electromagnetic suction valve provided on a high pressure fuel supply pump. In the present invention, in order to achieve the above object, the mass of a member which collides by magnetic attractive force is reduced to reduce the noise to be generated.
Hitachi Automotive Systems, Ltd.


06/09/16
20160159915 

Antibody constant region variant


By means of amino acid sequence alterations, the present inventors succeeded in providing constant regions that can confer antibodies with favorable properties, particularly as pharmaceuticals. The variants of the constant regions provided by the present invention will remarkably reduce heterogeneity when applied to antibody production.
Chugai Seiyaku Kabushiki Kaisha


06/09/16
20160158167 

Therapeutic agents for use in the propylaxis and/or treatment of hyperkinetic movement disorders


(rs)-[2-(3,4-dimethoxyphenyl)ethyl][2-hydroxy-3-(3-methylphenoxy)propyllamine having the formula (ia), or a pharmaceutically acceptable salt thereof for the formulation of a pharmaceutical composition is useful for the prophylaxis and/or the treatment of hyperkinetic movement disorders associated with huntington's disease, wilson's disease, tourette syndrome, restless leg syndrome, and tardive dyskinesia.. .
Som Innovation Biotech, S.l.


06/09/16
20160157971 

Controlling of sintering kinetics of oxide ceramics


The invention relates to multi-layer oxide ceramic bodies and in particular to presintered multi-layer oxide ceramic blanks and oxide ceramic green bodies suitable for dental applications. These bodies can be thermally densified by further sintering without distortion and are thus particularly suitable for the manufacture of dental restorations.
Ivoclar Vivadent Ag


06/09/16
20160157417 

Method for metering granular material and metering granular material


Disclosed are a method for metering granular material, such as seeds, fertilizer, or the like, in particular within a distribution unit or sowing unit of a distribution machine or sowing machine as well as a corresponding metering apparatus. By way of the method, the granular material being carried and conveyed by an airflow and/or by its own kinetic energy is directed through a feed tube into a metering unit, where it is guided along an approximately circular arc path and tangentially directed into an outlet tube, which is adjacent to the metering unit and which runs, at least in a section, slightly curved.
Horsch Maschinen Gmbh




Kinetic topics: Spectrometer, Mass Spectrometer, Physiologic, Ion Channel, Communication Channel, Rectilinear, Storage Device, Generators, Downstream, Coordinates, Transverse, Energy Absorber, Connecting Rod, Biomolecule, Magnetic Field

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