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Intraperitoneal

Intraperitoneal-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Insulin analogues with a glucose-regulated conformational switch
Case Western Reserve University
March 01, 2018 - N°20180057559

A two-chain insulin analogue contains an a chain modified by (i) a monomeric glucose-binding element at or near its n terminus and (ii) a b chain modified by at or near its c terminus by an element that reversibly binds to the monomeric glucose-binding element such that this linkage is displaceable by glucose. The monomeric glucose-binding element may be phenylboronic ...
Substituted 2,3-dihydroimidazo[1,2-c]quinazoline-containing combinations
Bayer Healthcare Pharmaceuticals Inc.
March 01, 2018 - N°20180055851

The present invention relates to combinations of: component a: one or more 2,3-dihydroimidazo[1,2-c]quinazoline compounds of general formula (a1) or (a2), or a physiologically acceptable salt, solvate, hydrate or stereoisomer thereof; component b: one or more substituted 5-(1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]-triazin-4-amine compounds of general formula (b), or a physiologically acceptable salt, solvate, hydrate or stereoisomer thereof; ...
Adaptive peritoneal dialysis intra-session adjustments for overall session optimization
Medtronic, Inc.
February 15, 2018 - N°20180043078

The invention relates to systems and methods for adjusting one or more dialysis parameters for delivering a peritoneal dialysis cycle to a patient based on patient or system parameters. The systems and methods include various sensors, flow paths, and processors to adjust the dialysis parameters used to deliver peritoneal dialysis therapy, for a specific peritoneal dialysis cycle. For example, a ...
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Nanoparticle conjugates of highly potent toxins and intraperitoneal administration of nanoparticles for treating or imaging ...
Massachusetts Institute Of Technology
January 11, 2018 - N°20180008687

Disclosed are methods of treating cancer of the intraperitoneal cavity using compositions comprising nanoparticles without targeting agents. In addition, nanoparticles are described that comprise a highly toxic anticancer agent (e. G., an anticancer agent having an ic50 less than 1 nm) covalently bound via a linker to a triblock copolymer. Other nanoparticles that comprise pt(iv) and an anticancer agent are ...
Composition and methods based on neutralizing antibodies delivered intranasally for enhanced therapeutic efficacy
Contrafect Corporation
November 23, 2017 - N°20170334974

The present invention provides methods for treatment or prophylaxis of viruses, particularly influenza virus, by administration of agents, particularly neutralizing antibodies or active fragments thereof, directly to the respiratory tract, including by intranasal or inhalation administration. The invention provides compositions suitable for intranasal or inhalation treatment and administration. The invention includes methods for treatment or prophylaxis combining intranasal or inhalation ...
Metallic gold cluster molecules as therapeutic agents for arthritic animals
October 26, 2017 - N°20170304408

A therapeutic method for attenuating symptoms of inflammation and autoimmune diseases. This method includes preparing and administering to animals intraperitoneally or orally a metallic gold cluster complex preparation.
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Method of quickly producing antibodies against avian influenza and maintain antibody titer of duck
South China Agricultural University
August 31, 2017 - N°20170246289

The present invention provides a method for enabling ducklings to quickly produce anti-avian influenza antibodies and maintain antibody titer, including: step 1) the first immunization is performed on ducklings at the age of 5 to 15 days: each duckling is inoculated with an avian influenza inactivated antigen in an abdomen, and simultaneously intramuscularly or subcutaneously immunized with an avian influenza inactivated oil-emulsion vaccine. ...
Compositions for the treatment of peritonitis
Reponex Pharmaceuticals Aps
August 17, 2017 - N°20170232069

The present invention provides compositions comprising granulocyte-macrophage colony-stimulating factor and antimicrobial agents for the treatment, pre-emptive treatment or prevention of infectious peritonitis or intra-abdominal infection by intraperitoneal administration of the compositions.
Reducing post-operative adhesion formation with intraperitoneal glutamine
Adetherapeutics Inc.
July 20, 2017 - N°20170203013

Intraperitoneal administration of glutamine to reduce adhesions in the peritoneum of a patient.
Intraperitoneal chemotherapy medical devices, kits, and methods
Cook Medical Technologies Llc
June 08, 2017 - N°20170157359

Medical devices useful in the delivery of chemotherapeutic agents, kits and methods are described. An example catheter comprises an elongate member having an elongate member proximal end, an elongate member distal end, and an elongate member main body extending between the elongate member proximal end and the elongate member distal end. The elongate member main body defines an elongate member ...
Medical treatment system and methods using a plurality of fluid lines
Deka Products Limited Partnership
June 08, 2017 - N°20170157310

A medical treatment system, such as peritoneal dialysis system, may include control and other features to enhance patient comfort and ease of use. For example, a peritoneal dialysis system may include a control system that can adjust the volume of fluid infused into the peritoneal cavity to prevent the intraperitoneal fluid volume from exceeding a pre-determined amount. The control system ...
Blood glucose control system
The General Hospital Corporation
April 06, 2017 - N°20170095612

Techniques are used for adaptation of drug-administration parameters that control insulin delivery in a blood glucose control system. One technique provides long-term adaptation of a nominal basal infusion rate, adapting to longer-term changes in a patient's needs due to growth, illness, hormonal fluctuations, physical activity, aging, etc. Another technique provides adaptation of priming dose size at mealtimes for overall better ...
Animal model for evaluating filoviruses
The Board Of Regents Of The University Of Texas System
March 30, 2017 - N°20170089884

The present invention includes methods of making, and compositions comprising, a uniformly lethal filovirus for outbred small mammals by mutation of the viral genome through serial passages in a small mammal, the method comprising the steps of: obtaining a filovirus strain from a human subject; passing the filovirus strain one or more times by intramuscular injection of one or more ...
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Composition and methods based on neutralizing antibodies delivered intranasally for enhanced therapeutic efficacy
Contrafect Corporation
January 05, 2017 - N°20170002062

The present invention provides methods for treatment or prophylaxis of viruses, particularly influenza virus, by administration of agents, particularly neutralizing antibodies or active fragments thereof, directly to the respiratory tract, including by intranasal or inhalation administration. The invention provides compositions suitable for intranasal or inhalation treatment and administration. The invention includes methods for treatment or prophylaxis combining intranasal or inhalation ...
Methods for producing high concentration lyophilized pharmaceutical formulations
Merck Sharp & Dohme Corp.
December 29, 2016 - N°20160375133

The present invention relates to methods of producing lyophilized pharmaceutical compositions comprising a high concentration of therapeutic protein or antibody prior to lyophilization, wherein the lyophilized formulation can be reconstituted with a diluent in about 15 minutes or less. The invention also relates to the high concentration lyophilized formulations produced by the methods described herein. The lyophilized formulations produced by the ...
Compositions and methods for treating ovarian cancer including preventing the recurrence thereof
University Of Southern California
November 03, 2016 - N°20160317610

A method of treating ovarian cancer (oc) includes administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising vicrostatin and/or a protein substantially similar to vicrostatin. The administration is preferably performed intraperitoneally. The methods may include concurrently or sequentially administering to the patient one or more additional treatments for ovarian cancer. A pharmaceutical composition ...
Electromyography with prosthetic or orthotic devices
Össur Iceland Ehf
October 20, 2016 - N°20160302686

Systems, devices and methods for control of a prosthetic or orthotic device (pod) based on electromyography (emg) signals are described. The pod may be a lower or upper limb pod having one or more joints. One or more emg sensors may detect the emg signals. The emg sensors may be external, subcutaneous, intraperitoneal, epimysial, intramuscular, or other types. Control of ...
Method and system for producing and delivering airless medical ice slurry to induce hypothemia
June 23, 2016 - N°20160175141

The present invention relates to a method and system for producing and delivering sterile, airless, and highly loaded ice slurry for inducing therapeutic hypothermia. The method is capable of producing and delivering ice slurry in a patient to induce hypothermia through internal and external cooling methods such as subcutaneous, intravascular, intraperitoneal, gastrointestinal, and lung methods. The method is capable of ...
Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
Insmed Incorporated
June 16, 2016 - N°20160166608

One aspect of the invention relates to methods of treating cancer in a patient comprising administering intraperitoneally to a patient in need thereof a cancer treating effective amount of a composition comprising a lipid-complexed platinum compound wherein the concentration of the platinum compound of the lipid-complexed platinum compound composition is greater than about 1. 2 mg/ml. Another aspect of the invention ...
Method for inducing artificial ovulation and spawning of fresh-water eels
Googol Holdings Co., Ltd
May 19, 2016 - N°20160135436

According to an example, artificial ovulation and spawning of freshwater eels may be induced to promote artificial ovulation without employing intraperitoneal injection, by feeding a feminization-inducing material (e. G., 17β-estradiol) for inducing feminization during a predetermined period into a raising bath in which broodfish are raised and, when an ovulation induction period arrives, adding pituitary extracts of catadromous ...
Medical treatment system and methods using a plurality of fluid lines
April 14, 2016 - N°20160101278

Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination ...
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