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Intestinal Diseases patents

      

This page is updated frequently with new Intestinal Diseases-related patent applications.




 Substituted prolines / piperidines as orexin receptor antagonists patent thumbnailSubstituted prolines / piperidines as orexin receptor antagonists
The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as ox1 or ox2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. For example, orexin receptor-modulatory compounds of the present invention can be used in treatment of an eating disorder, obesity, alcoholism or an alcohol-related disorder, drug abuse or addiction including addiction to cocaine, opiates, amphetamines, or nicotine, a sleep disorder, a cognitive dysfunction in a psychiatric or neurologic disorder, depression, anxiety, panic disorder, schizophrenia, alzheimer's disease, parkinson's disease, huntington's chorea, headache, migraine, pain, gastrointestinal diseases, epilepsy, inflammations, immune-related diseases, endocrine-related diseases, cancer, hypertension, behavior disorder, mood disorder, manic depression, dementia, sex disorder, psychosexual disorder, or renal disease..
Eolas Therapeutics, Inc.


 Bacterial phospholipase inhibitors as modulator of colonic bacterial flora patent thumbnailBacterial phospholipase inhibitors as modulator of colonic bacterial flora
The present invention relates to the field of gastroenterology and, more particular, to the field of intestinal diseases. More specifically, it concerns uses and methods for the treatment of inflammatory bacterial diseases of the intestine.
Universitaetsklinikum Heidelberg


 Novel lactobacillus plantarum and composition containing the same patent thumbnailNovel lactobacillus plantarum and composition containing the same
The present invention provides lactobacillus plantarum cjlp56 kctc 11402bp, a composition containing the lactobacillus for treating intestinal diseases, and a composition containing the lactobacillus for enhancing immunity.. .
Cj Cheiljedang Corp.


 Piperidine compounds, pharmaceutical composition comprising the same and its use patent thumbnailPiperidine compounds, pharmaceutical composition comprising the same and its use
Piperidine compounds and pharmaceutically useful salts thereof, a pharmaceutical composition including an effective amount of the racemic or enantiomerically enriched piperidine compounds to treat gastrointestinal diseases, and a method of treating gastrointestinal diseases in a mammal are provided.. .
Sk Biopharmaceuticals Co., Ltd.


 Fluorinated arylalkylaminocarboxamide derivatives patent thumbnailFluorinated arylalkylaminocarboxamide derivatives
Fluorinated arylalkylaminocarboxamide derivatives of formula (i) are described wherein w, j, n, r1, r2, r2′, r3, r4, r5 and r6 have the meanings as defined in the specification and pharmaceutically salts thereof, pharmaceutical compositions containing them as active ingredients and their use as sodium and/or calcium channel modulators useful in preventing, alleviating and curing a wide range of pathologies, including neurological, psychiatric, cardiovascular, inflammatory, ophthalmic, urolological, and gastrointestinal diseases, where the above mechanisms have been described as playing a pathological role.. .
Newron Pharmaceuticals S.p.a.


 Use and identification of biomarkers for gastrointestinal diseases patent thumbnailUse and identification of biomarkers for gastrointestinal diseases
The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug discovery, monitoring of treatment efficacy, and diagnostics. The invention further provides methods for identifying a therapeutic target to treat ulcerative colitis, colorectal cancer, and crohn's disease..
Alfagene Bioscience, Inc.


 Drug for disease caused by expression of periostin except eye disease, and use thereof patent thumbnailDrug for disease caused by expression of periostin except eye disease, and use thereof
The present invention is intended to provide a novel molecule that inhibits the expression of the periostin gene that is effective in treatment of diseases caused by the expression of periostin except for eye diseases. A drug for a disease caused by the expression of periostin except for an eye disease includes, as an expression inhibitory sequence for the periostin gene, a nucleic acid molecule including a nucleotide that has a base sequence represented by any one of seq id nos: 1 to 19.
Aqua Therapeutics Co., Ltd.


 Compositions and methods to image and quantify inflammation patent thumbnailCompositions and methods to image and quantify inflammation
Compositions and methods for assessing inflammation in a subject. The present disclosure provides compositions for labeling leukocytes with a 19f-containing perfluoropolyether molecule ex vivo.
Celsense, Inc.


 Methods of using diaminopyrimidine p2x3 and p2x2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases patent thumbnailMethods of using diaminopyrimidine p2x3 and p2x2/3 receptor modulators for treatment of respiratory and gastrointestinal diseases
Wherein d, x, y, r1, r2, r3, r4, r5, r6, r7 and r8 are as defined herein.. .

 Quinine compounds, and optical isomers, preparation method and medical use thereof patent thumbnailQuinine compounds, and optical isomers, preparation method and medical use thereof
The present invention discloses a class of quinine compounds and pharmaceutically acceptable salts, solvates, prodrugs or optical isomers thereof. Also disclosed in the present invention are that the above compounds have a selective antagonistic effect on the receptor subtypes of m1 and m3, but have no significant effect on m2 receptor subtype, and the above compounds are characterized by rapid action, long-lasting efficacy, and low toxic and side-effects when used to treat rhinitis, post-cold rhinitis, chronic trachitis, airway hyperresponsiveness, asthma, chronic obstructive pulmonary diseases, cough, urinary incontinence, frequent urination, unstable bladder syndrome, bladder spasms, bladder inflammation and gastrointestinal diseases such as irritable bowel syndrome, spastic colitis, as well as duodenal and gastric ulcers..
Beijing Fswelcome Technology Development Co., Ltd


Compositions and methods to image and quantify inflammation

Compositions and methods for assessing inflammation in a subject. The preset disclosure provides compositions for labeling leukocytes with a 19f-containing perfluoropolyether molecule ex vivo.
Celsense, Inc.

Compositions and methods for treatment and prophylaxis of gastrointestinal diseases

Methods and compositions for treating inflammatory bowel disease, irritable bowel syndrome, and travelers' diarrhea involve the use of targeted antibiotics in combination with probiotic formulations. The probiotics mitigate many of the deleterious side effects associated with antibiotic use and permit the antibiotic to be administered at a higher dose and for a longer duration than would otherwise be possible in the absence of the probiotic.

Compositions and methods

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .
Seres Therapeutics, Inc.

Compositions and methods

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .

Pharmaceutical cyclosporin compositions

An oral cyclosporin composition comprises minicapsules having a core containing a cyclosporin, especially cyclosporin a in a solubilised liquid form. The minicapsules have a release profile to release the pre-solubilised cyclosporin, at least in the colon.
Sigmoid Pharma Limited

Multi-tailed lipids and uses thereof

The present invention provides multi-tailed lipid compounds, and salts and stereoisomers thereof, and methods of preparing the compounds. Also provided are compositions including a compound of the invention and an agent (e.g., an sirna, mrna, plasmid dna, small molecule, protein, peptide).
Massachusetts Institute Of Technology

Composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit

The present invention relates to a composition for preventing and treating gastrointestinal diseases by using litsea japonica, and specifically, to a composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit as an active ingredient. According to the present invention, the essential oils extracted from litsea japonica fruits (pure fruit, seed fruit, and seeds) and used as the active ingredient of the composition for preventing and treating gastrointestinal diseases have been confirmed to have excellent effects in an efficacy evaluation for relieving gastrointestinal diseases caused by helicobacter pylori, which is a gastrointestinal disease factor, physical factors induced by stress, and chemical factors induced by indomethacin.
Jeju Technopark

Compositions and methods for the treatment of inflammatory bowel disease

The invention relates to the compounds of formula i and formula ii or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i or formula ii; and methods for treating or preventing inflammatory bowel disease may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.
Cellix Bio Private Limited

Compositions and methods for the treatment of inflammatory bowel disease

The invention relates to the compounds of formula i and formula ii or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i or formula ii; and methods for treating or preventing inflammatory bowel disease may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection.

Bicyclic derivative containing pyrimidine ring, and preparation method therefor

The present invention provides: a bicyclic derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof; a preparation method therefor, a pharmaceutical composition comprising the same; and a use therefor. According to the present invention, the bicyclic compound derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof acts as a 5-ht4 receptor agonist, and thus can be usefully applied to the prevention or treatment of dysfunction in gastrointestinal motility, for example, gastrointestinal diseases such as gastroesophageal reflux disease (gerd), constipation, irritable bowel syndrome (ibs), dyspepsia, post-operative ileus, delayed gastric emptying, gastroparesis, intestinal pseudo-obstruction, drug-induced delayed transit, diabetic gastric atony and the like..
Yuhan Corporation

Brush-poly (glycoamidoamine)-lipids and uses thereof

Which may assist the pgal and/or a complex of the pgal and an agent to pass through cell membranes or be taken up by cells. Also provided are compositions including a described pgal and an agent (e.g., polynucleotide, small molecule, peptide, or protein).

Compositions and methods for binding cysteinyl leukotrienes (cyslts) for treatment of disease

Methods are provided for using antibodies and antibody fragments that bind one or more cysteinyl leukotrienes (cyslts) for treatment of diseases, including inflammatory, respiratory and gastrointestinal diseases and conditions associated with aberrant levels of one or more cyslts. Anti-cyslt antibodies and antigen-binding antibody fragments, and compositions containing such antibodies and antibody fragments, are also provided..
Lpath, Inc.

Method for producing monoclonal iga antibody

The present invention provides a component having effects in vivo of improving or optimizing the intestinal environment, suppressing intestinal putrefaction, or suppressing alternation of intestinal bacterial growth and/or pathological changes of intestinal bacterial growth in gut microbiota. The invention also provides an active ingredient suitably used for treating intestinal diseases.
Kansai Bunri Sogo Gakuen

Lipid compositions for the treatment of gastro-intestinal disorders and the promotion of intestinal development and maturation

The present invention provides a use of a lipid composition for the preparation of a nutritional, pharmaceutical or nutraceutical composition or a functional food, for the prevention and treatment of gastrointestinal diseases and disorders, and for promoting intestinal development, maturation, adaptation and differentiation.. .
Enzymotec Ltd.

Methods, compounds, and compositions for the treatment of angiotensin-related diseases

Disclosed are small molecule non-peptidic compounds, as well as methods and compositions for the treatment of angiotensin-related diseases and disorders, including cardiovascular diseases, metabolic diseases, gastrointestinal diseases, renal diseases, inflammatory/autoimmune diseases, neurological diseases, bone marrow diseases and cancer.. .
University Of Southern California

Polyamine-fatty acid derived lipidoids and uses thereof

The present disclosure provides polyamine-fatty acid derived lipidoids (e.g., compounds of formula (i) or (ii)) and methods of preparing the lipidoids. A described lipidoid includes r—c(═o)—o— moieties (where r is a lipid moiety), which may be hydrolyzed into non-toxic fatty acids.
Massachusetts Institute Of Technology

Hydroxyindalpine derivatives and their medical use

The present invention relates to hydroxyindalpine derivatives of formula (i) as defined herein and pharmaceutical compositions comprising these compounds, as well as their medical use, particularly in the treatment or prevention of gastrointestinal diseases/disorders, such as constipation and functional dyspepsia.. .
Technische UniversitÄt MÜnchen

Novel lactobacillus plantarum and composition comprising same

The present invention provides lactobacillus plantarum cjlp133 kctc 11403bp, a composition for treating intestinal diseases comprising the lactic acid bacteria, and a composition for enhancing immunity comprising the lactic acid bacteria.. .
Cj Cheiljedang Corp

Use of microorganisms for the prevention and treatment of intestinal diseases

The invention relates to acetylcholine-producing microorganisms for use in the prevention and/or treatment of intestinal diseases, and/or reduction of risks of intestinal diseases, and/or improvement of intestinal health as well as promoting healthy gut flora. The acetylcholine-producing microorganisms may be provided as a pharmaceutical dosage form or as additive to functional food or food supplemental products.
Ludwig Stocker Hofpfisterei Gmbh

Pyridine derivatives as soft rock inhibitors

The present invention relates to new kinase inhibitors of formula (i) or a stereoisomer, tautomer, racemic, salt, hydrate, or solvate thereof, and more specifically to rock inhibitors, compositions, in particular pharmaceuticals, comprising such inhibitors, and to uses of such inhibitors in the treatment and prophylaxis of disease. In addition, the invention relates to methods of treatment and use of said compounds in the manufacture of a medicament for the application to a number of therapeutic indications including respiratory and gastro-intestinal diseases..
Amakem Nv



Intestinal Diseases topics:
  • Intestinal Diseases
  • Gastrointestinal Diseases
  • Gastrointestinal Disease
  • Gastrointestinal
  • Budesonide
  • Pharmaceutically Acceptable Salt
  • Neurological
  • Inflammatory Bowel Disease
  • Bowel Disease
  • Pharmaceutically Acceptable Salts
  • Psychiatric
  • Urogenital
  • Pathologic
  • Antagonist
  • Inflammation


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    This listing is a sample listing of patent applications related to Intestinal Diseases for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Intestinal Diseases with additional patents listed. Browse our RSS directory or Search for other possible listings.


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