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Intestinal Diseases

Intestinal Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Compositions and methods
Seres Therapeutics, Inc.
July 13, 2017 - N°20170196914

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
Bacterial phospholipase inhibitors as modulator of colonic bacterial flora
Universitaetsklinikum Heidelberg
June 22, 2017 - N°20170173165

The present invention relates to the field of gastroenterology and, more particular, to the field of intestinal diseases. More specifically, it concerns uses and methods for the treatment of inflammatory bacterial diseases of the intestine. In particular, it relates to diseases that are associated with bacterial invasion of the intestinal mucus, including, inflammatory bowel diseases, and infectious bacterial diseases. Therefore, ...
Substituted prolines / piperidines as orexin receptor antagonists
Eolas Therapeutics, Inc.
April 13, 2017 - N°20170101410

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as ox1 or ox2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. ...
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Novel lactobacillus plantarum and composition containing the same
Cj Cheiljedang Corp.
December 22, 2016 - N°20160367608

The present invention provides lactobacillus plantarum cjlp56 kctc 11402bp, a composition containing the lactobacillus for treating intestinal diseases, and a composition containing the lactobacillus for enhancing immunity.
Piperidine compounds, pharmaceutical composition comprising the same and its use
Sk Biopharmaceuticals Co., Ltd.
December 15, 2016 - N°20160362374

Piperidine compounds and pharmaceutically useful salts thereof, a pharmaceutical composition including an effective amount of the racemic or enantiomerically enriched piperidine compounds to treat gastrointestinal diseases, and a method of treating gastrointestinal diseases in a mammal are provided.
Fluorinated arylalkylaminocarboxamide derivatives
Newron Pharmaceuticals S.p.a.
November 17, 2016 - N°20160332959

Fluorinated arylalkylaminocarboxamide derivatives of formula (i) are described wherein w, j, n, r1, r2, r2′, r3, r4, r5 and r6 have the meanings as defined in the specification and pharmaceutically salts thereof, pharmaceutical compositions containing them as active ingredients and their use as sodium and/or calcium channel modulators useful in preventing, alleviating and curing a wide range of ...
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Drug for disease caused by expression of periostin except eye disease, and use thereof
Aqua Therapeutics Co., Ltd.
October 20, 2016 - N°20160304866

The present invention is intended to provide a novel molecule that inhibits the expression of the periostin gene that is effective in treatment of diseases caused by the expression of periostin except for eye diseases. A drug for a disease caused by the expression of periostin except for an eye disease includes, as an expression inhibitory sequence for the periostin ...
Compositions and methods to image and quantify inflammation
Celsense, Inc.
October 13, 2016 - N°20160296642

Compositions and methods for assessing inflammation in a subject. The present disclosure provides compositions for labeling leukocytes with a 19f-containing perfluoropolyether molecule ex vivo. In some examples, the leukocytes are obtained from the patient, enriched in a whole blood fraction, and then labeled. The labeled cells may be re-introduced into the patient. The leukocytes may accumulate at a site of ...
Quinine compounds, and optical isomers, preparation method and medical use thereof
Beijing Fswelcome Technology Development Co., Ltd
August 25, 2016 - N°20160244439

The present invention discloses a class of quinine compounds and pharmaceutically acceptable salts, solvates, prodrugs or optical isomers thereof. Also disclosed in the present invention are that the above compounds have a selective antagonistic effect on the receptor subtypes of m1 and m3, but have no significant effect on m2 receptor subtype, and the above compounds are characterized by rapid ...
Compositions and methods to image and quantify inflammation
Celsense, Inc.
August 18, 2016 - N°20160235872

Compositions and methods for assessing inflammation in a subject. The preset disclosure provides compositions for labeling leukocytes with a 19f-containing perfluoropolyether molecule ex vivo. In some examples, the leukocytes are obtained from the patient, enriched in a whole blood fraction, and then labeled. The labeled cells may be re-introduced into the patient. The leukocytes may accumulate at a site of ...
Compositions and methods for treatment and prophylaxis of gastrointestinal diseases
Celsense, Inc.
July 21, 2016 - N°20160206564

Methods and compositions for treating inflammatory bowel disease, irritable bowel syndrome, and travelers' diarrhea involve the use of targeted antibiotics in combination with probiotic formulations. The probiotics mitigate many of the deleterious side effects associated with antibiotic use and permit the antibiotic to be administered at a higher dose and for a longer duration than would otherwise be possible in ...
Compositions and methods
Seres Therapeutics, Inc.
July 14, 2016 - N°20160199423

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
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Intestinal Diseases Patent Applications
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Pharmaceutical cyclosporin compositions
Sigmoid Pharma Limited
June 16, 2016 - N°20160166635

An oral cyclosporin composition comprises minicapsules having a core containing a cyclosporin, especially cyclosporin a in a solubilised liquid form. The minicapsules have a release profile to release the pre-solubilised cyclosporin, at least in the colon. The composition may be used for treating a range of intestinal diseases [fig. 10].
Multi-tailed lipids and uses thereof
Massachusetts Institute Of Technology
June 09, 2016 - N°20160158363

The present invention provides multi-tailed lipid compounds, and salts and stereoisomers thereof, and methods of preparing the compounds. Also provided are compositions including a compound of the invention and an agent (e. G., an sirna, mrna, plasmid dna, small molecule, protein, peptide). The present invention also provides methods, and kits using the compositions for delivering an agent to a subject (...
Composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit
Jeju Technopark
May 12, 2016 - N°20160129065

The present invention relates to a composition for preventing and treating gastrointestinal diseases by using litsea japonica, and specifically, to a composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit as an active ingredient. According to the present invention, the essential oils extracted from litsea japonica fruits (pure fruit, seed fruit, and seeds) and ...
Compositions and methods for the treatment of inflammatory bowel disease
Cellix Bio Private Limited
May 05, 2016 - N°20160120839

The invention relates to the compounds of formula i and formula ii or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i or formula ii; and methods for treating or preventing inflammatory bowel disease may be formulated for oral, buccal, rectal, topical, transdermal, ...
Compositions and methods for the treatment of inflammatory bowel disease
Cellix Bio Private Limited
May 05, 2016 - N°20160120838

The invention relates to the compounds of formula i and formula ii or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i or formula ii; and methods for treating or preventing inflammatory bowel disease may be formulated for oral, buccal, rectal, topical, transdermal, ...
Bicyclic derivative containing pyrimidine ring, and preparation method therefor
Yuhan Corporation
March 31, 2016 - N°20160090374

The present invention provides: a bicyclic derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof; a preparation method therefor, a pharmaceutical composition comprising the same; and a use therefor. According to the present invention, the bicyclic compound derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof acts as a 5-ht4 receptor agonist, and thus can be ...
Brush-poly (glycoamidoamine)-lipids and uses thereof
Yuhan Corporation
March 10, 2016 - N°20160067346

Which may assist the pgal and/or a complex of the pgal and an agent to pass through cell membranes or be taken up by cells. Also provided are compositions including a described pgal and an agent (e. G., polynucleotide, small molecule, peptide, or protein). The present disclosure also provides methods, kits, and uses that include or involve the pgals ...
Compositions and methods for binding cysteinyl leukotrienes (cyslts) for treatment of disease
Lpath, Inc.
March 03, 2016 - N°20160060328

Methods are provided for using antibodies and antibody fragments that bind one or more cysteinyl leukotrienes (cyslts) for treatment of diseases, including inflammatory, respiratory and gastrointestinal diseases and conditions associated with aberrant levels of one or more cyslts. Anti-cyslt antibodies and antigen-binding antibody fragments, and compositions containing such antibodies and antibody fragments, are also provided.
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