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Inflammatory Disease

Inflammatory Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Receptor trem (triggering receptor expressed on myeloid cells) and uses thereof
Novo Nordisk A/s
November 09, 2017 - N°20170320946

Novel activating receptors of the ig super-family expressed on human myeloid cells, called trem(s) (triggering receptor expressed on myeloid cells) are provided. Specifically, two (2) members of trems, trem-1 and trem-2 are disclosed. Trem-1 is a transmembrane glycoprotein expressed selectively on blood neutrophils and a subset of monocytes but not on lymphocytes and other cell types and is upregulated by ...
Administration of a selective il-6-trans-signalling inhibitor
Ferring B.v.
November 09, 2017 - N°20170320932

A selective il-6-trans-signalling inhibitor can be used to treat a variety of il-6-mediated conditions, including inflammatory diseases and cancer. The inhibitor can safely be administered to humans at a variety of doses. Moreover, the inhibitor lessens deleterious effects associated with other il-6 inhibitors such as lowering neutrophil counts, platelet counts and levels of c-reactive protein.
Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases
Allergan, Inc.
November 09, 2017 - N°20170320897

The present invention relates to a method for treating ocular inflammatory diseases in a subject in need of such treatment, which comprises administering a pharmaceutical composition comprising a therapeutically effective amount of at least one agonist of formyl peptide receptor 2.
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Inflammatory Disease Patent Applications
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  • 291+ full patent PDF documents of Inflammatory Disease-related inventions.
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Pharmaceutical compositions containing a pde4 inhibitor and a pi3 delta or dual pi3 delta-gamma kinase ...
Rhizen Pharmaceuticals Sa
November 09, 2017 - N°20170319558

This present invention relates to a method of treating a autoimmune, respiratory and/or inflammatory disease or condition (e. G., psoriasis, rheumatoid arthritis, asthma, copd). The method comprises administering a pi3k delta inhibitor or a dual pi3k delta-gamma inhibitor and a pde4 inhibitor. The present invention also relates to pharmaceutical compositions containing a pi3k delta or dual ...
Compounds and methods for modulating vascular injury
The Regents Of The University Of California
November 09, 2017 - N°20170319529

Methods of modulating healing response to vascular injury and/or vascular scarring in a subject are provided. As such, aspects of the disclosure relate to the use of pro-resolving lipid mediators to modulate inflammation and/or restenosis of a vascular wall. Another aspect of the disclosure relates to the use of pro-resolving lipid mediators to modulate a biological activity of ...
Method of diagnosing and treating brain endothelial inflammation related disease
The Regents Of The University Of California
November 02, 2017 - N°20170315133

The presently claimed invention relates to materials and methods for diagnosing a chronic inflammatory disease in a patient comprising testing a biological sample from the patient for a level of a first neurovascular biomarker of lymphatic activation and diagnosing the patient as having the chronic inflammatory disease if the tested level of the first neurovascular biomarker of lymphatic activation is ...
Inflammatory Disease Patent Pack
Download 291+ patent application PDFs
Inflammatory Disease Patent Applications
Download 291+ Inflammatory Disease-related PDFs
For professional research & prior art discovery
inventor
  • 291+ full patent PDF documents of Inflammatory Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Isoindoline derivative, intermediate, preparation method, pharmaceutical composition and use thereof
The Regents Of The University Of California
November 02, 2017 - N°20170313676

Provided are an isoindoline derivative, intermediate, preparation method, pharmaceutical composition and use thereof. The isoindoline derivative and the pharmaceutical composition thereof can regulate the production or activity of immunological cytokines, thus effectively treating cancer and inflammatory disease.
Lactone compounds and methods of making and using same
The Regents Of The University Of California
November 02, 2017 - N°20170313669

Provided herein are lactone compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as inhibitors of serine hydrolases, such as abhd16a. Furthermore, the subject compounds and compositions may be useful for the treatment of, for example, pharc and other neuroinflammatory diseases.
Method for the synthesis of hydroxy-triglycerides and uses thereof for the prevention and treament of ...
The Regents Of The University Of California
November 02, 2017 - N°20170313646

The present invention relates to hydroxy-triglycerides, their synthesis, a pharmaceutical and/or nutraceutical composition which comprises at least one of said hydroxy-triglycerides, and a method which comprises the administration to a patient of a therapeutically effective quantity of at least one of said hydroxy-triglycerides or at least one of said pharmaceutical and/or nutraceutical compositions, for the prevention and/or ...
Use of recombinant lymphocyte activation gene-3 as a companion therapeutic for patients at risk for ...
The Regents Of The University Of California
November 02, 2017 - N°20170312338

A method for classifying patients at risk for cardiovascular disease, other chronic inflammatory diseases, cardiovascular and/or non-cardiovascular morbidity and mortality based on a risk assessment for lymphocyte activation gene 3 (lag3) protein deficiency, and for mediating the risk using recombinant lymphocyte activation gene-3 or lag3 mimetic as a companion therapeutic alone or in combination with a statin and/or an ...
Tyrosine kinase inhibitor formulations for the treatment of mast cell-mediated inflammatory diseases and methods of ...
The Regents Of The University Of California
November 02, 2017 - N°20170312282

Methods of treating mast cell-mediated inflammatory diseases are provided by local administration a therapeutically effective amount of a tyrosine kinase inhibitor to a patient in need thereof.
Pyrimidine compounds as jak kinase inhibitors
The Regents Of The University Of California
November 02, 2017 - N°20170312280

Wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of jak kinases. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat gastrointestinal and other inflammatory diseases, and processes and intermediates useful for preparing such compounds.
1-pyrazolyl-3-(4-((2-anilinopyrimidin-4 -yl) oxy) napththalen-1 - yl) ureas as p38 map knase inhibitors
The Regents Of The University Of California
November 02, 2017 - N°20170312279

There are provided compounds of formula (i) which are inhibitors of the family of p38 mitogen-activated protein kinase enzymes, and to their use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, such as asthma and copd.
Inflammatory Disease Patent Pack
Download 291+ patent application PDFs
Inflammatory Disease Patent Applications
Download 291+ Inflammatory Disease-related PDFs
For professional research & prior art discovery
inventor
  • 291+ full patent PDF documents of Inflammatory Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Pharmaceutical composition for cancer prevention and treatment, containing ndrg3 expression or activity inhibitor as active ...
Korea Research Institute Of Bioscience And Biotechnology
October 26, 2017 - N°20170306047

The present invention relates to a pharmaceutical composition for preventing and treating cancer or inflammatory disease, containing an ndrg3 expression or activity inhibitor as an active ingredient. Furthermore, the present invention relates to an ndrg3 protein-specific antibody and a use thereof. Specifically, the antibody to the ndrg3 protein is prepared, and the antibody is used to verify that ndrg3 mediated ...
Anti-cd100 antibodies and methods for using the same
Vaccinex, Inc.
October 26, 2017 - N°20170306017

Compositions and methods are provided for treating diseases associated with cd100, including certain autoimmune diseases, inflammatory diseases, and cancers. In particular, anti-cd100 monoclonal antibodies have been developed to neutralize cd100.
Modified pigment epithelium-derived factor (pedf) peptides and uses thereof for treating neovascular diseases, inflammatory diseases, ...
Northwestern University
October 26, 2017 - N°20170305998

Disclosed are modified pigment epithelium-derived factor (pedf) peptides, particulate carrier prodrugs thereof, and pharmaceutical compositions comprising the peptides or particulate carrier prodrugs. The peptides, particulate carrier prodrugs, and pharmaceutical compositions may be used to treat diseases and disorders that are amenable to treatment with anti-angiogenic agents, anti-tumorigenic agents, anti-fibrotic agents, chemotherapy-protecting agents, and immune stimulating agents
Antagonistic dr3 ligands
Novo Nordisk A/s
October 26, 2017 - N°20170305994

The present invention relates to treatment of inflammatory diseases. In particular, the present invention relates to antagonistic dr3 ligands useful for treating inflammatory diseases.
Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
Glycomimetics, Inc.
October 26, 2017 - N°20170305951

Compounds, compositions, and methods for treatment and/or prevention of cancer and inflammatory diseases, and for releasing cells such as stem cells (e. G., bone marrow progenitor cells) into circulating blood and enhancing retention of the cells in the blood are disclosed. For example, heterobifunctional compounds that inhibit both e-selectins and cxcr4 chemokine receptors are described and pharmaceutical compositions comprising ...
Crystalline forms of a bruton's tyrosine kinase inhibitor
Pharmacyclics Llc
October 26, 2017 - N°20170305919

Described herein is the bruton's tyrosine kinase (btk) inhibitor 1-((r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the btk inhibitor, as well as methods of using the btk inhibitor, alone or in combination with other ...
Antigen binding proteins that bind wisp1
Sorrento Therapeutics, Inc.
October 26, 2017 - N°20170304442

There is disclosed compositions and methods relating to or derived from anti-wisp1 antibodies. More specifically, there is disclosed fully human antibodies that bind wisp1, wisp1-binding fragments and derivatives of such antibodies, and wisp1 binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods ...
Methods of modulating immune system responses
The Governing Council Of The University Of Toronto
October 26, 2017 - N°20170304435

Novel methods and uses for modulating immune responses are provided. The methods and uses involve the use of a tifa activator such heptose-1,7-5 bisphosphate or an analogue or derivative thereof. The methods may be used to activate, inhibit or otherwise modify an immune response so as to either prevent or treat infectious or inflammatory diseases or cancer. Also provided ...
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