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Inflammation

Inflammation-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Novel pentadienoyl piperidine derivative and use thereof
Snu R&db Foundation
November 09, 2017 - N°20170320825

The present invention relates to a novel pentadienoyl piperidine derivative, a pharmaceutical composition containing the same for prevention or treatment of metabolic diseases, and a functional food composition using the same for improvement or relief of metabolic diseases. The pentadienoyl piperidine derivative of the present invention inhibits the differentiation of preadipocytes, reduces body weight, visceral fat, blood lipid levels, and ...
Fap-activated therapeutic agents, and uses related thereto
Trustees Of Tufts College
November 09, 2017 - N°20170319609

Disclosed are prodrugs of anthracyclines (such as doxorubicin) and derivatives thereof that are selectively cleaved and activated by fibroblast activating protein (fap). The prodrugs are useful for targeted delivery of “warhead” anthracycline or anthracycline derivative to fap-expressing tissues, including cancer (e. G., solid tumors). Also provided are pharmaceutical compositions comprising the prodrugs, as well as methods ...
Compounds and methods for modulating vascular injury
The Regents Of The University Of California
November 09, 2017 - N°20170319529

Methods of modulating healing response to vascular injury and/or vascular scarring in a subject are provided. As such, aspects of the disclosure relate to the use of pro-resolving lipid mediators to modulate inflammation and/or restenosis of a vascular wall. Another aspect of the disclosure relates to the use of pro-resolving lipid mediators to modulate a biological activity of ...
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Inflammation Patent Applications
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Method and apparatus for heated massage therapy
Elc Management Llc
November 09, 2017 - N°20170319419

A method and apparatus for the treatment of, and reduction of inflammation caused by, carpal tunnel syndrome.
Methods and devices for protective filtration and delivery of respirable compounds
Elc Management Llc
November 09, 2017 - N°20170318874

The present invention relates generally to methods for the delivery of beneficial respirable compounds such as moisture, anti-inflammation compounds, anti-irritants, fragrances, aromatherapy compounds, and low dose medications slowly and continuously over time using a mask containing a thickened aqueous gel media delivery system combined with, supported by, and coating solid bodies inside the filter. The present invention also relates generally ...
Method of diagnosing and treating brain endothelial inflammation related disease
Elc Management Llc
November 02, 2017 - N°20170315133

The presently claimed invention relates to materials and methods for diagnosing a chronic inflammatory disease in a patient comprising testing a biological sample from the patient for a level of a first neurovascular biomarker of lymphatic activation and diagnosing the patient as having the chronic inflammatory disease if the tested level of the first neurovascular biomarker of lymphatic activation is ...
Inflammation Patent Pack
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Inflammation Patent Applications
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For professional research & prior art discovery
inventor
  • 558+ full patent PDF documents of Inflammation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Fused heterocyclic compounds as selective bmp inhibitors
Elc Management Llc
November 02, 2017 - N°20170313701

The present invention provides small molecule inhibitors of bmp signaling. These compounds may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with bmp signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as for modulating cellular differentiation and/or proliferation.
Isoquinolin-3-yl carboxamides and preparation and use thereof
Elc Management Llc
November 02, 2017 - N°20170313681

Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of wnt pathway signaling (e. G., cancer, abnormal cellular proliferation, angiogenesis, alzheimer's disease, lung disease, inflammation, auto-immune diseases and osteoarthritis), the modulation of cellular events mediated ...
Novel carboxylic acid compounds useful for inhibiting microsomal prostaglandin e2 synthase-1
Elc Management Llc
November 02, 2017 - N°20170313679

The present invention provides compounds of formula 1, or a pharmaceutically acceptable salts, thereof, where r, x, a, e, and g are as described herein, methods of preparing the compounds, and use of the compounds to treat pain and/or inflammation.
Bis(sulfonamide) derivatives and their use as mpges inhibitors
Elc Management Llc
November 02, 2017 - N°20170313672

The present invention relates to bis(sulfonamide) compounds and pharmaceutically acceptable salts thereof. The present invention also relates to pharmaceutical compositions comprising these compounds and to their use as a medicament for the treatment and/or prevention of a disease, disorder or condition in which modulation of microsomal prostaglandin e synthase-1 activity is beneficial, such as pain, inflammation and cancer.
Use of recombinant lymphocyte activation gene-3 as a companion therapeutic for patients at risk for ...
Elc Management Llc
November 02, 2017 - N°20170312338

A method for classifying patients at risk for cardiovascular disease, other chronic inflammatory diseases, cardiovascular and/or non-cardiovascular morbidity and mortality based on a risk assessment for lymphocyte activation gene 3 (lag3) protein deficiency, and for mediating the risk using recombinant lymphocyte activation gene-3 or lag3 mimetic as a companion therapeutic alone or in combination with a statin and/or an ...
Topical use of prg4 for treatment of allergy and symptoms of inflammation
Elc Management Llc
November 02, 2017 - N°20170312335

Disclosed are methods involving the therapeutic use of human prg4 (prg4) protein, to ameliorate the symptoms associated with allergies and/or respiratory infections.
Methods and compositions for treating inflammatory disorders
Elc Management Llc
November 02, 2017 - N°20170312334

Disclosed herein, in certain embodiments, are methods and compositions for treating inflammatory disorders. In some embodiments, the methods comprise co-administering synergistic combinations of modulators of inflammation.
Inflammation Patent Pack
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Inflammation Patent Applications
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For professional research & prior art discovery
inventor
  • 558+ full patent PDF documents of Inflammation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Compositions and methods for lipid metabolism disorder
Elc Management Llc
November 02, 2017 - N°20170312286

A method for inhibiting a lipid metabolism disorder of a warm-blooded animal includes administering a therapeutically effective amount of a compound being one selected from the group consisting of phosphodiesterase 5 (pde-5) inhibitors of the first type and second type and a statin analogue to a warm-blooded animal suffering from the lipid metabolism disorder. The method may treat the disease selected ...
Cosmetic composition for improving anti-oxidation, anti-inflammation and atopic skin by using fermented black tea liquid ...
Elc Management Llc
November 02, 2017 - N°20170312216

Disclosed are a cosmetic composition for improving anti-oxidation, anti-inflammation and atopic skin by using fermented liquid of black tea as an effective ingredient and a method of preparing the same. The cosmetic composition includes the fermented black tea liquid obtained by primarily fermenting black tea with saccharomyces, secondarily fermenting the black tea with gluconacetobacter and tertiarily fermenting the black tea ...
Pharmaceutical composition for cancer prevention and treatment, containing ndrg3 expression or activity inhibitor as active ...
Korea Research Institute Of Bioscience And Biotechnology
October 26, 2017 - N°20170306047

The present invention relates to a pharmaceutical composition for preventing and treating cancer or inflammatory disease, containing an ndrg3 expression or activity inhibitor as an active ingredient. Furthermore, the present invention relates to an ndrg3 protein-specific antibody and a use thereof. Specifically, the antibody to the ndrg3 protein is prepared, and the antibody is used to verify that ndrg3 mediated ...
Administration of agents for the treatment of inflammation
Biogen Idec Ma, Inc.
October 26, 2017 - N°20170306026

A method of chronically reducing a patient's pathological inflammation via the administration of an agent that specifically binds to an alpha-4 integrin or a dimer comprising an alpha-4 integrin is disclosed. The agent provided must have a binding affinity such that administration is sufficient to suppress pathological inflammation, and the agent is administered chronically to provide long-term suppression of pathological ...
Selective nav protein binders
Kymab Limited
October 26, 2017 - N°20170306013

The invention provides antibodies and fragments thereof which bind to human nav1. 7, as well as nucleic acids, vectors, host cells and hybridomas for making the same. Further provided are pharmaceutical compositions for use in treating, preventing and/or reducing the risk of a nav1. 7-mediated conditions or diseases, such as pain, inflammation, and metabolic/chronic diseases. The invention additionally provides ...
Compositions and methods for inhibiting bmp
University Of Houston System
October 26, 2017 - N°20170305883

The present invention provides small molecule inhibitors of bmp signaling and compositions and methods for inhibiting bmp signaling. These compounds and compositions may be used to modulate cell growth, differentiation, proliferation, and apoptosis, and thus may be useful for treating diseases or conditions associated with bmp signaling, including inflammation, cardiovascular disease, hematological disease, cancer, and bone disorders, as well as ...
Systems and methods for preventing, mitigating, and/or treating dementia
University Of Houston System
October 26, 2017 - N°20170304584

The present disclosure provides systems and methods for at least one of preventing, reducing, and treating a level of or change in at least one of amyloid-β (aβ) peptide, c-terminal fragment-β (β-ctf), β-secretase (bace1), γ-secretase, neuroinflammation, and/or dementia (e. G., alzheimer's disease or age-related decline) in a ...
Extracellular matrix sheet structures
Aziyo Med, Llc
October 26, 2017 - N°20170304507

A sheet structure formed from an extracellular matrix (ecm) composition that includes acellular ecm derived from small intestine submucosa (sis) tissue, gentamicin and vancomycin. The sheet structure is configured to modulate inflammation of damaged biological tissue and induce cell and tissue proliferation, bioremodeling of the damaged biological tissue, and regeneration of new tissue and tissue structures with site-specific structural and ...
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