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Inflammation

Inflammation-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Compositions and methods for monitoring, diagnosis, prognosis, detection, and treatment of cancer
Glax Llc
January 11, 2018 - N°20180010195

The present invention relates to the field of cancer and inflammation, and in particular methods of monitoring, diagnosis, prognosis, detecting, treating and preventing cancer and inflammation conditions. The use of composition comprises method of monitoring, diagnosis, prognosis, and detecting cancer and inflammation with en2 and/or satb2 expression and/or activity. The pharmaceutical composition will further comprise agents that inhibit ...
Methods for the treatment of disease using immunoglobulins having fc regions with altered affinities for ...
Macrogenics, Inc.
January 11, 2018 - N°20180009902

The present invention relates to methods of treating or preventing cancer and other diseases using molecules, particularly polypeptides, more particularly immunoglobulins (e. G., antibodies), comprising a variant fc region, wherein said variant fc region comprises at least one amino acid modification relative to a wild-type fc region, which variant fc region binds an fcγr that activates a ...
Anti-cd154 antibodies having impaired fcr binding and/or complement binding properties and use in therapy
The Trustees Of Dartmouth College
January 11, 2018 - N°20180009896

Improved anti-cd154 antibodies are provided herein which have ablated fcr binding and/or complement binding/activation. The use of these antibodies for inducing tolerance and treating immune diseases including autoimmunity, inflammation and allergic disorders is disclosed herein.
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Inflammation Patent Applications
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Mutant chicken interleukin-1beta protein as chicken interleukin-1beta antagonist and uses thereof
National Tsing Hua University
January 11, 2018 - N°20180009867

The present invention provides a mutant chicken interleukin-1β protein as a chicken interleukin-1β antagonist, which has a substituted peptide at position 117 and/or 118 of wild-type chicken interleukin-1β peptides. The mutant chicken interleukin-1β protein is created by using point mutation in a method genetic engineering; it can significantly inhibit proliferation of avian virus, ...
Compositions and methods of using islet neogenesis peptides and analogs thereof
Shenzhen Hightide Biopharmaceutical, Ltd.
January 11, 2018 - N°20180009861

The invention provides peptides and analogs of ingap and hip peptides. The peptides and analogs can be used in methods for treating various diseases and conditions. Such diseases and conditions can include impaired pancreatic function, treating a metabolic disease, for example, diabetes, both type 1 and type 2 diabetes, islets induction, expansion and proliferation for trans plantation, promoting neuroprotection or nerve regeneration, ...
Inhibitors of trka kinase
Gvk Biosciences Private Limited
January 11, 2018 - N°20180009781

The present invention is directed to the compounds of formula i which are inhibitors of tropomyosin-related kinase a (trka): formula (i) or steroisomers, tautomers or a pharmaceutically acceptable salts, metabolites, isotopes, solvates or prodrugs thereof, wherein, ra, rb, rc, rd, r1, r2, l and het-ar are as defined herein. These compounds can be used for the preventive and/or therapeutic ...
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Inflammation Patent Applications
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  • 558+ full patent PDF documents of Inflammation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Probiotic for infantile colic
Venpharma Laboratorios, S. A.
January 11, 2018 - N°20180008652

The invention provides a bacterial composition which comprises from 104 to 1012 cfu/g of pediococcus pentosaceus cells which have the ability to induce the production of interleukin-10 to reduce inflammation in the intestinal tract among other features. Thus, the bacterial composition is useful in the amelioration of excessive crying in infants. Particularly, pediococcus pentosaceus cells are from the strain deposited as ...
Nutritional compositions comprising human milk oligosaccharides and nucleotides and uses thereof for treating and/or ...
Abbott Laboratories
January 11, 2018 - N°20180008623

Disclosed are nutritional compositions including human milk oligosaccharides and nucleotides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
Methods of treating neurological inflammatory disorders
Mayo Foundation For Medical Education And Research
January 11, 2018 - N°20180008620

Methods of treating neurological inflammatory disease or seizures caused by neuroinflammation by administering cpmp are described. Treating neuroinflammatory and neurometabolic diseases with cpmp is described so as to override dyshomeostasis in the moco synthesis pathway and control synaptic inhibition in the gephyrin-gabar pathway. This is a novel strategy for preventing neural circuit dyshomeostasis by stabilizing inhibitory synapses.
Oral pharmacological composition including 5--2,2-dimethyl-4-(3-fluorophenyl)-3(2h)-furanone having crystalline structure with ...
Crystalgenomics, Inc.
January 11, 2018 - N°20180008571

The present invention relates to a pharmaceutical composition including (i) as a major ingredient, a novel 5-{4-(aminosulfonyl)phenyl}-2,2-dimethyl-4-(3-fluorophenyl)-3(2h)-furanone compound (formula 1) or a pharmaceutically acceptable salt thereof, which has a crystalline form a or g, or a mixed form thereof and has a 50% volume particle diameter (d(0. 5)) of 3 μm to 9 &#...
Use of short chain fatty acids in cancer prevention
Temple University-of The Commonwealth System Of Higher Education
January 11, 2018 - N°20180008565

The invention relates to compositions for preventing or delaying the onset of hepatocellular cancer. The compositions of the invention may comprise short chain fatty acids. The compositions of the invention may also comprise probiotic bacteria. The compositions of the invention include compositions for preventing or delaying the onset of hepatocellular cancer by treating or preventing liver inflammation, liver disease, and ...
Inflammatory disease diagnosis and methods of treatment using lipopolysaccharide-responsive beige-like anchor
University Of South Florida
January 04, 2018 - N°20180002413

Anti-cytokine therapy has revolutionized immunological disease treatment, but is not always effective and subject to treatment resistance as the cytokine cascade is highly redundant and multiple cytokines are involved in inflammation. Targeting a critical common regulator of inflammatory effectors is desirable. Lipopolysaccharide (lps)-responsive beige-like anchor (lrba) is a master regulator of multiple genes important for inflammation. Subcellular localization shows ...
Cyclic dinucleotides useful for the treatment of inter alia cancer
University Of South Florida
January 04, 2018 - N°20180002369

Or a pharmaceutically acceptable salt and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases and conditions in which modulation of sting (stimulator of interferon genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious ...
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Inflammation Patent Applications
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  • 558+ full patent PDF documents of Inflammation-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Antioxidant inflammation modulators: oleanolic acid derivatives with amino and other modifications at c-17
Acturum Real Estate Ab
January 04, 2018 - N°20180002277

Wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.
Method for producing a horseshoe
Value Feet
January 04, 2018 - N°20180001371

Disclosed is a method for producing a horseshoe, wherein the following steps are carried out: a) at least partially viewing the hoof (16) to be shod in order to determine the required measurements for producing a shoe that fits the hoof, b) processing the measurements in order to deduce a provisional shape of the horseshoe, c) recording definitive parameters of the ...
Genetically modified mesenchymal stem cells expressing alpha-1 antitrypsin (aat)
Apceth Gmbh & Co. Kg
January 04, 2018 - N°20180000969

Genetically modified mesenchymal stem cells can be used as a medicament in the treatment of medical conditions associated with inflammation and/or an unwanted immune response in subjects without an alpha1-antitrypsin (aat) deficiency. The stem cells include an exogenous nucleic acid, which includes (i) an alpha-1 antitrypsin (aat) encoding region operably linked to (ii) a promoter or promoter/enhancer ...
Viral rna segments as immunomodulatory agents and vaccine components
The University Of Iowa Research Foundation
January 04, 2018 - N°20180000925

The disclosure provides compositions and methods involving viral rna segments for use in modulating immune responses, including inhibition inflammation related to pathogenic t-cell activation. In addition, modification of the viral sequences responsible for modulating immune response provides for improved vaccine formulations.
Compositions containing combinations of bioactive molecules derived from microbiota for treatment of disease
Riken
January 04, 2018 - N°20180000921

Compositions consisting of bioactive molecules derived from the microbiota of a mammal are provided herein. When administered orally with a colonic delivery system, the compositions are useful for the prophylaxis and treatment of diseases, in particular inflammatory, autoimmune and infectious diseases. The compositions comprise combinations of small molecules and bacterial antigens formulated in colonic delivery systems. Use of the compositions ...
Composition and methods for treating ischemic wounds and inflammatory conditions
Southwest Technologies, Inc.
January 04, 2018 - N°20180000905

Methods, compositions, and treatment protocols for treating ischemic wounds and inflammatory conditions in a patient. The treatment protocols comprise or consist of using a modified collagen gel (mcg) to promote healing of ischemic wounds and reduce inflammation at the wound site and in other inflammatory conditions. The modified collagen gel comprises generally a dispersion of collagens in an aqueous matrix ...
Systems andmethods to improve organor tissue function andorganor tissue transplant longevity
Proterris, Inc.
January 04, 2018 - N°20180000859

The present invention provides for systems and methods for inhaled co therapy to prevent, attenuate, or delay processes that accelerate the loss of organ or tissue function, thereby increasing the lifespan of transplanted organs or tissues, or slowing the decline of native organs or tissues, or delaying the need for replacement of diseased native organs with organ transplants. Such biological ...
Antioxidant agent, and antioxidant cosmetic and uv care cosmetic
Ezaki Glico Co., Ltd.
January 04, 2018 - N°20180000856

The present invention provides an antioxidant, an ros inhibitor, an antioxidant enzyme production promoter, an antioxidant cosmetic, a uv care cosmetic, a prophylactic or therapeutic agent for gastrointestinal tract inflammation, and an antioxidant food or beverage, each containing an enzymatically synthesized glycogen (esg) or an α-amylase digest (rg) thereof, as well as use for enhancing an antioxidative effect ...
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