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Inflammation patents

      

This page is updated frequently with new Inflammation-related patent applications.




 Identification of inflammation in tissue images patent thumbnailIdentification of inflammation in tissue images
Systems and methods are provided for identifying markers for inflammation in a tissue image. The tissue image is captured as an image of a histology slide.
University Of California


 Therapeutic antibodies patent thumbnailTherapeutic antibodies
The present invention concerns human antibodies recognising the human c5a receptor. By binding to c5ar the antibodies inhibit c5a signalling, whereby the pro-inflammatory signal is inhibited.
Novo Nordisk A/s


 Pyridone and aza-pyridone compounds and methods of use patent thumbnailPyridone and aza-pyridone compounds and methods of use
Pyridone and aza-pyridone compounds of formula i are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting btk kinase, and for treating immune disorders such as inflammation mediated by btk kinase. Methods of using compounds of formula i for in intro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed..
Genentch Inc.


 Heterocyclyl-butanamide derivatives patent thumbnailHeterocyclyl-butanamide derivatives
In which w, x and y have the meanings indicated in claim 1, are inhibitors of tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.. .

 Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses patent thumbnailCycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses
The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, alzheimer's disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, syndrome x, thrombotic disorder. Compounds and methods of the invention can also be used to modulate c reactive protein or enhance bile production in a patient.
Esperion Therapeutics, Inc.


 Inflammation-enabling polypeptides and uses thereof patent thumbnailInflammation-enabling polypeptides and uses thereof
This present technology relates to the use of inflammation-enabling polypeptides (or their coding sequences) to screen for agents useful for the prevention, treatment and/or alleviations of symptoms associated with an inflammatory disorder, to identify individuals susceptible of developing an exacerbated inflammatory response as well as to determine if a therapeutic regimen is capable of preventing, treating or alleviating the symptoms associated to an inflammatory disorder in an individual. The present technology also provides methods for preventing, treating and/or alleviating the symptoms associated to an inflammatory condition based on the inhibition of expression or activity of the inflammation-enabling targets..
The Royal Institution For The Advancement Of Learning/mcgill University


 Treatment of metabolic disorders in equine animals patent thumbnailTreatment of metabolic disorders in equine animals
A sglt2 inhibitor or a pharmaceutically acceptable form thereof is provided for use in the treatment and/or prevention of a metabolic disorder of an equine animal. In particular, a sglt2 inhibitor or a pharmaceutically acceptable form thereof is provided for use in the treatment and/or prevention of insulin resistance, hyperinsulinemia, impaired glucose tolerance, dyslipidemia, dysadipokinemia, subclinical inflammation, systemic inflammation, low grade systemic inflammation, obesity, and/or regional adiposity in an equine animal..
Boehringer Ingelheim Vetmedica Gmbh


 Ultrapure tetrahydrocannabinol-11-oic-acids patent thumbnailUltrapure tetrahydrocannabinol-11-oic-acids
This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.. .
Corbus Pharmaceuticals, Inc.


 Ultrapure tetrahydrocannabinol-11-oic acids patent thumbnailUltrapure tetrahydrocannabinol-11-oic acids
This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.. .
Corbus Pharmaceuticals, Inc.


 Ultrapure tetrahydrocannabinol-11-oic acids patent thumbnailUltrapure tetrahydrocannabinol-11-oic acids
This application is in the field of medicinal chemistry and relates to ultrapure ajulemic acid, its synthesis, pharmaceutical compositions and methods of use thereof for the treatment and/or prevention of inflammation, pain, and fibrotic diseases including scleroderma, systemic sclerosis, scleroderma-like disorders, sine scleroderma, liver cirrhosis, interstitial pulmonary fibrosis, idiopathic pulmonary fibrosis, dupuytren's contracture, keloids, chronic kidney disease, chronic graft rejection, and other scarring-wound healing abnormalities, post-operative adhesions, and reactive fibrosis.. .
Corbus Pharmaceuticals, Inc.


Orally administered corticosteroid compositions

The present invention is directed to orally administered corticosteroid compositions. The present invention also provides a method for treating a condition associated with inflammation of the gastrointestinal tract in an individual.
Adare Pharmaceuticals, Inc.

Minimally-invasive measurement of esophageal inflammation

The methods and apparatus of the present invention allow the evaluation of inflammation of the esophagus. Measurements may be utilized, for example, to diagnose a disease of the esophagus, to monitor inflammation of the esophagus, or to access the treatment of a disease of the esophagus.
The Board Of Trustees Of The University Of Illinois

Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier

Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of treating or preventing autoimmune disorders, inhibiting inflammatory mechanisms in the gut, and/or tightening gut mucosal barrier function are disclosed.. .
Synlogic, Inc.

Analogs of fexaramine and methods of making and using

Embodiments of a method of making the same, and of a composition comprising them are disclosed herein. Also disclosed are embodiments of a method of treating or preventing a metabolic disorder in a subject, comprising administering to a subject (e.g., via the gastrointestinal tract) a therapeutically effective amount of one or more of the disclosed compounds, thereby activating fxr receptors in the intestines, and treating or preventing a metabolic disorder in the subject.

Par-1 activation by metalloproteinase-1 (mmp-1)

Matrix metalloproteases (mmps) play many important roles in normal and pathological remodeling processes including atherothrombotic disease, inflammation, angiogenesis and cancer. This invention relates to the activation of protease-activated receptor-1 (par-1) by endogenous platelet mmp-1 collagenase on the surface of platelets.
Tufts Medical Center, Inc.

Nutraceutical composition and use thereof

A nutraceutical composition comprising water having an alkaline ph and a plurality of members of the group consisting of orange extract, vanilla extract, apple honey, agave syrup, apple cider vinegar, olive oil, coconut oil, liquid multivitamin, aloe vera juice, flax seed oil, hemp oil, and elephant garlic, wherein each of the plurality of members is present in an amount effective to ameliorate the effects of inflammation and raise energy levels when administered to a mammal.. .

Regenerative cell therapy for central nervous system (cns) disorders and ptsd

Provided herein are compositions comprising regenerative cells (e.g., from adipose tissue), for therapy for central nervous system (cns) disorders, including disorders characterized by excitotoxicity, neuroinflammation, neurodegeneration, and compromise of the blood brain barrier.. .
Cytori Therapeutics, Inc.

Treatments of ocular allergy with alcaftadine

Compositions, kits and methods for the treatment or prevention of ocular allergies and inflammation and the symptoms thereof comprising alcaftadine or a pharmaceutically acceptable salt thereof.. .
Vistakon Pharmaceuticals, Llc

Pharmaceutical use of 3, 4-bis-benzylsulfonylbutyronitrile

The present invention is directed to a method of treating inflammation or pain. The present invention is also directed to a method of treating an inflammatory skin disease or disorder, such as dermatitis, psoriasis, acne, or rosacea.
Olatec Therapeutics Llc

Compositions for anti-inflammatory, antioxidant effects and improved respiratory function by specific histone deacetylase inhibition

Compositions comprising lsf compositions and treatment regiments comprising administration of lsf containing compositions are disclosed. Compositions and/or regiments may optionally include the administration of vitamins, minerals, and anti-oxidants.

Pharmaceutical composition

The present invention is directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and ω-(methylsulfonyl)alkylamine or ω-(methylsulfonyl)alkylamide. The present invention is also directed to a method for treating inflammation, inflammatory-related disorders, or pain, by administering ω-(methylsulfonyl)alkylamine or ω-(methyl sulfonyl)alkylamide, or a pharmaceutically acceptable salt or solvate thereof to a subject in need thereof..
Olatec Therapeutics Llc

Light inhibitors for asthma, lung and airway inflammation, respiratory, interstitial, pulmonary and fibrotic disease treatment

Methods of treating inflammatory conditions, disease and disorders are provided. Method include, for example, contacting or administering a sufficient amount of a light inhibitor to a subject to treat the inflammatory condition, disease or disorder..
La Jolla Institute For Allergy And Immunology

Macrocyclic therapeutic agents, methods of manufacture, and methods of treatment

The instant invention describes macrocyclic compounds having therapeutic activity, and the mechanism and methods of treating disorders such as autoimmune diseases, inflammation, and cancer, tumors and cell proliferation related disorders.. .
University Of Florida Research Foundation, Incorporated

Substituted pyridazines as prostacyclin receptor modulators

Cyclohexane derivatives of formula ia and pharmaceutical compositions thereof that modulate the activity of the pgi2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pulmonary arterial hypertension (pah) and related disorders; platelet aggregation; coronary artery disease; myocardial infarction; transient ischemic attack; angina; stroke; ischemia-reperfusion injury; restenosis; atrial fibrillation; blood clot formation in an angioplasty or coronary bypass surgery individual or in an individual suffering from atrial fibrillation; atherosclerosis; atherothrombosis; asthma or a symptom thereof; a diabetic-related disorder such as diabetic peripheral neuropathy, diabetic nephropathy or diabetic retinopathy; glaucoma or other disease of the eye with abnormal intraocular pressure; hypertension; inflammation; psoriasis; psoriatic arthritis; rheumatoid arthritis; crohn's disease; transplant rejection; multiple sclerosis; systemic lupus erythematosus (sle); ulcerative colitis; ischemia-reperfusion injury; restenosis; atherosclerosis; acne; type 1 diabetes; type 2 diabetes; sepsis; and chronic obstructive pulmonary disorder (copd)..
Arena Pharmaceuticals, Inc.

Treating infection

The present invention relates to surfactant protein d (sp-d) or nucleic acids encoding sp-d or variants thereof such as surfactant protein a or mannan binding lectin for use in the treatment and/or prevention of a parasitic infection. Methods for determining the presence of a parasitic infection by determining levels of sp-d in a sample are also disclosed.
University Of Cape Town

Therapeutic compositions

A therapeutic topical composition comprising achillea millefolium (yarrow) extract, aloe vera, arnica montana flowers, annatto seed extract, boswellia serrate extract, marigold flower extract, cetearyl olivate, cetyl myristoleate, sunflower seed oil, sorbitan olivate, turmeric root extract, methylsulfonylmethane (msm), emu oil, devil's claw root extract, yerba mate leaf extract, magnesium sulfate, peppermint oil, menthol, skullcap root extract, vitamin e, and yucca root extract useful for treatment of localized pain, inflammation, and/or swelling, and methods for making and using the composition.. .
Anc Products, Llc

Use of a composition comprising arabic gum (ag) for improving gut impermeability

The use of a nutritional composition including arabic gum (ag) improves gut impermeability. The nutritional composition also improves conditions like abdominal pain, chronic or not, insomnia, bloating, flatulence, shortness of breath, gluten intolerance, malnutrition, muscle cramps, multiple chemical sensitivities, muscle pain, myofascial pain, mood swings, poor exercise tolerance, poor immunity, poor memory, recurrent skin rashes, brittle nails, hair loss, food allergies, constipation, diarrhea, liver dysfunction, brain fatigue, abdominal spasms, constant hunger pains, depleted appetite, irritable bowel syndrome, chemotherapy, food allergies, acne, liver dysfunction or inflammation of the bowel..
Nexira International

Application of fructus schisandrae total polysaccharides in preparatoin of medicine or nutraceuticals used for treating coughing

The present invention relates to a new application of fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals for treating coughing, and more specifically to a new application of fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals for preventing and relieving coughing and eliminating airway inflammation. Experiments demonstrate that the fructus schisandrae total polysaccharides can remarkably reduce the coughing times of a guinea pig with increased cough sensitivity induced by cigarette smoke and an acute cough guinea pig induced by citric acid smoke, prolong the latent period of cough, and significantly reduce the airway inflammation of the guinea pig with increased cough susceptibility induced by cigarette smoke, so that the fructus schisandrae total polysaccharides can be used for preparing drugs for preventing cough, relieving cough and eliminating airway inflammation..
State Key Laboratory Of Respiratory Disease

Method of dietary treatment for genetic and epigenetic diseases and disorders

Genetic and epigenetic diseases and disorders are treated with fda approved dietary compositions in the form of dietary supplements and nutraceuticals. The diseases and disorders to be treated include rett syndrome, trinucleotide repeat diseases such as fragile x syndrome, memory impairment, chronic inflammation, pre-cancerous conditions which involve cancer stem cells, and post-cancerous conditions which involve cancer stem cells which have survived in spite of cancer treatment.

Autoimmune disorder treatment using rxr agonists

The present specification provides rxr agonist compounds, compositions comprising such rxr agonists, and methods using such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection as well as use of such rxr agonists to manufacture a medicament and use of such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection.. .
Dartmouth College

Medicant eluting adjuncts and methods of using medicant eluting adjuncts

Various exemplary devices and methods are provided for performing surgical procedures. In general, one or more adjuncts can be used in conjunction with surgical instruments.
Ethicon Endo-surgery, Llc

Matrix metalloproteinase inhibiting adjuncts for surgical devices

Various exemplary matrix metalloproteinase (mmp) inhibiting adjuncts for surgical devices are provided. In general, an implantable adjunct can be configured to be applied to tissue by a surgical stapler in conjunction with staples.
Ethicon Endo-surgery, Llc

Method and system for simultaneous evaluation of airway wall density and airway wall inflammation

A method of evaluating airway wall density and inflammation including: segmenting a bronchial tree to create an airway wall map; for each branch, taking a set of locations that form the wall of each branch from the map and sampling the value in a virtual non-contrast image of the bronchial tree and, given a set of samples of pre-contrast densities, computing a value to yield a bronchial wall density for each branch to yield density measures; for each branch, taking the set of locations that form the wall of each branch from the map and sampling the value in a contrast agent map of the bronchial tree and, given the set of samples of contrast agent intake, computing a value to yield a bronchial wall uptake for each branch to yield inflammation measures; and using the density and inflammation measures to determine treatment or predict outcome for a patient.. .
Siemens Healthcare Gmbh

Automated comparison of 3d images

A method and apparatus for automated comparison of 3d images, such as specific shapes in images, for example, for detecting vascular changes and aneurysm growth. The method comprises an adaptive geodesic active contour (gac) approach which can be performed in a single pass, or across multiple iterations.
The Regents Of The University Of California

Methods and materials for characterizing intestinal barrier function

The present invention the present invention provides methods and materials related to the characterization of intestinal barrier function, and related methods for preventing and/or treating intestinal barrier dysfunction. In particular, the present invention provides methods and materials for characterizing intestinal barrier function within mammals (e.g., humans) through determining the level, presence, and/or frequency of biomarkers for intestinal function (e.g., functional enterocyte mass, enterocyte integrity, paracellular tight junction function, gut inflammation) within a biological sample..
The Arizona Board Of Regents On Behalf Of The University Of Arizona

Inhibitors of nf kappa-b activity for treatment of diseases and disorders

Peptides and methods of use thereof, are disclosed for use in treating various disease and disorders, including inflammation, pain, oral mucositis, oral lesions, and cancer. The peptides modulate the activity of the transcription factor nf κb..

Small molecule inhibitors of g protein coupled receptor 6 kinases polypeptides

This document relates to inhibitors of g protein coupled receptor 6 kinase (grk6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.. .
Mayo Foundation For Medical Education And Research

Ganciclovir derivatives for modulating innate and adaptive immunity and for use in immunotherapy

Compositions and methods for modulating innate and adaptive immunity and for use in immunotherapy are disclosed. In particular, the invention relates to novel ganciclovir derivatives and methods of using them for the treatment of immune-related disorders, including inflammation, autoimmunity, and infections, and neurological disorders, and cancer..
The Board Of Trustees Of The Leland Stanford Junior University

Small molecule inhibitors of g protein coupled receptor 6 kinase polypeptides

This document relates to inhibitors of g protein coupled receptor 6 kinase (grk6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.. .
Mayo Foundation For Medical Education And Research

Heteroaryl compounds useful as inhibitors of e1 activating enzymes

This invention relates to compounds that inhibit e1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia..
Millennium Pharmaceuticals, Inc.

Compositions containing extracts of curcuma longa and echinacea angustifolia which are useful to reduce peripheral inflammation and pain

The present invention relates to compositions containing, as their only active ingredients, an extract of curcuma spp, optionally as curcumin in the form of a complex with phospholipids, and an extract selected from echinacea spp extract or lipophilic extract of zanthoxylum spp, which are useful in the topical and systemic treatment of peripheral pain and of superficial and deep inflammatory and painful conditions. The compositions according to the invention are particularly effective in the treatment of osteoarthritis and rheumatoid arthritis in patients unable to tolerate long-term treatment with nsaids or steroids..
Indena S.p.a.

Method of treating inflammation, allergy and asthma with a purified extract (atc1) isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient

The present invention relates to inventive novel industrialized method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of pseudolysimachion rotundum var subintegrum than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory, allergic or asthmatic disease. The purified extract showed more potent anti-inflammatory, anti-allergy and anti-asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinophil, the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and goblet cell hyperplasia in a ova-sensitized/challenged mouse model..
Korea Research Institute Of Bioscience And Biotechnology

Method of treating inflammation, allergy and asthma with a purified extract (atc2) isolated from pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient

The present invention relates to inventive novel industrialized method for preparing purified extract containing more abundant active ingredients such as catalpol derivatives from the extract of pseudolysimachion rotundum var subintegrum than that prepared by the conventional preparation method disclosed in the prior art and the therapeutics or functional health food comprising the purified extract for treating and preventing inflammatory, allergic or asthmatic disease. The purified extract showed more potent anti-inflammatory, anti-allergy and anti-asthma activity than that prepared by the conventional preparation method disclosed in the prior art through various in vivo tests such as inhibition test on the reproduction of eosinophil, the release of immunoglobulin and inflammatory chemokines in plasma and bronchoalveolar fluid as well as the suppression of airway hyperresponsiveness and goblet cell hyperplasia in a ova-sensitized/challenged mouse model..
Korea Research Institute Of Bioscience And Technology

Oral compositions and route of administration for the delivery of a thylakoid extract

A new use or method of use of a thylakoid extract, for oral route of administration, and a composition comprising the thylakoid extract in adjunction with an acceptable carrier for oral administration. Also described is a method for treating or preventing a disease or disorder involving the formation of reactive oxygen species inflammation in an individual, which comprises the step of orally administering an effective dose of a thylakoid extract.
Groupe Sante Devonian

Strontium based compositions and formulations for pain, pruritus, and inflammation

Therapeutically-active compositions and formulations for treating pain, pruritus, irritation, inflammation, and tissue damage due to the irritation and inflammation, and therapeutically-active compositions and formulations for wound management, including wounds that are at high risk for infection. Strontium and beta hydroxybutyrate based compositions and formulations which can be topically applied..
Cosmederm Bioscience, Inc.

Process for sustained neuromodulation of the nervous system

A water soluble polymer thin film of polyvinyl alcohol is manufactured and placed in contact with the skin, or through a buffering layer of cream, and then lightly sprayed on the exposed side with water to achieve conformal contact with the skin microstructures by transition from a solid state to a partial liquid/solid or gel state, and then upon drying back to a solid state. As the polymer thin film dries it contracts over a prolonged period, thereby producing a tightening effect of sustained tensile and compressive forces propagating through the skin surface layers with concurrent modulation of sensory nerve endings of the peripheral nervous system, with certain therapeutic effects depending upon the applied area, including reducing pain associated with arthritis or soreness of joint areas, inducing a relaxed and attentive cognitive state, inducing inflammation control or relief of cellular hydrostatic pressure, and reducing gastric reflex..
Transfer Devices, Inc.

Fast acting joint relief formulations

The instant invention provides a method and composition for treating or preventing osteoarthritis, joint effusion, joint inflammation and pain, synovitis, lameness, post operative arthroscopic surgery, deterioration of proper joint function including joint mobility, the reduction or inhibition of metabolic activity of chondrocytes, the activity of enzymes that degrade cartilage, said method comprising administering effective amounts of boswellia serrata, effective amounts of freeze dried green lipped mussle, effective amounts of white willow bark extract containing salicin, effective amounts of angelica root, effective amounts of glucosamine and salts thereof, effective amounts of chondroitin and salts thereof and effective amounts of omega 3 fatty acids.. .

Inhibitors of human phosphatidylinositol 3-kinase delta

Methods of inhibiting phosphotidylinositol 3-kinase delta isoform (pi3kδ) activity, and methods of treating disease, such as disorders of immunity and inflammation, in which pi3kδ plays a role in leukocyte function are disclosed. Preferably, the methods employ active agents that selectively inhibit pi3kδ, while not significantly inhibiting activity of other pi3k isoforms.
Icos Corporation

Surface-modified hybrid surface implant and manufacturing the same

The present invention relates to an implant having a nanotube on a surface thereof and a method for manufacturing the same, and more particularly, to an implant having excellent stability and effectiveness because a nanotube is provided on the surface of the implant and a nanocapsule loaded with a medicine or the like is attached to the nanotube, thereby strengthening the adhesive force with the peripheral soft tissue and allowing to stably load factors related to osteogenesis and inflammation prevention and treatment or the like, thus not making them lost during an implant procedure and therefore not only having an increased lifespan but also preventing almost all occurrences of side effects caused by the implant.. .

Otoscope and otoscopic method based on spectral analysis

The invention relates to an otoscope device (10), especially configured to be manipulated by a layperson during its application, comprising a radiation sensing unit (40.1) configured for detecting radiation reflected by the patient's outer ear, especially by the eardrum; wherein the otoscope device further comprises electronic and/or optic means (44) configured for determining spectral information of reflected radiation, especially with respect to wavelengths shorter than 500 nm to 480 nm, and configured for determining a ratio of radiation in the spectrum below 480 nm to 500 nm to radiation in the spectrum above 480 nm to 500 nm, especially based on a specific intensity of reflected radiation within the spectrum of blue light and/or uv radiation. Further, the invention relates to a method of identifying and/or locating objects in a subject's ear or to a method of identifying or characterizing an eardrum.
Helen Of Troy Limited

Icariin derivatives

Disclosed are derivatives of icariin. Disclosed are compounds having formula i-viii as defined herein.
H. Lee Moffitt Cancer Center And Research Institute, Inc.

Semicarbazide-sensitive amine oxidase inhibitors for use as analgesics in traumatic neuropathy and neurogenic inflammation

The invention relates to a compound having ssao/vap-1 inhibitor activity for use in the treatment of hyperalgesia and allodynia implicated in traumatic neuropathy or neurogenic inflammation. Accordingly, the invention relates to a compound having ssao/vap-1 inhibitor activity for use in the inhibition of pathological activation and dysfunctions of peptidergic sensory nerves caused by mechanical damage or chemical activation of peptidergic sensory nerves in neurogenic inflammation..
PÉcsi TudomÁnyegyetem



Inflammation topics:
  • Inflammation
  • Hypertension
  • Nephropathy
  • Pharmaceutically Acceptable Salt
  • Syndrome X
  • Therapeutics
  • Proliferation
  • Immune Disorder
  • Pathologic
  • Uterine Bleeding
  • Uterine Fibroids
  • Osteoporosis
  • Endometrial
  • Restenosis
  • Dysfunctional Uterine Bleeding


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    This listing is a sample listing of patent applications related to Inflammation for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Inflammation with additional patents listed. Browse our RSS directory or Search for other possible listings.


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