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Infectious-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).

Leukocyte esterase detection from throat swab
February 15, 2018 - N°20180044713

The present invention relates to the field of infectious diseases. The invention specifically relates to the diagnostic test for acute bacterial pharyngitis. The test is used in screening for group a beta haemolytic streptococcus by the identifying the presence of leukocyte esterase in the throat. The leukocyte esterase throat swab test is compared to the rapid step test for efficiency ...
Method and system for tissue treatment with critical/supercritical carbon dioxide
Warsaw Orthopedic, Inc.
February 15, 2018 - N°20180044639

Methods of decontaminating bone tissue and an apparatus or system for the same are provided. The methods can be multi-batch processes and include contacting the bone tissue having contaminants with carbon dioxide to decontaminate the bone tissue and to form carbon dioxide having contaminants. The contaminated carbon dioxide is collected and the contaminants are removed to obtain purified carbon dioxide ...
Immunomodulatory fusion proteins and uses thereof
Fred Hutchinson Cancer Research Center
February 15, 2018 - N°20180044404

The present disclosure relates to immunomodulatory fusion proteins containing an extracellular binding domain and an intracellular signaling domain, wherein binding of a target can generate a modulatory signal in a host cell, such as a t cell. The present disclosure also relates to uses of immune cells expressing such immunomodulatory fusion proteins to treat certain diseases, such as cancer or ...
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Infectious Patent Applications
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  • 268+ full patent PDF documents of Infectious-related inventions.
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Methods and apparatus to inactivate infectious agents on a drainage catheter residing in a body ...
February 15, 2018 - N°20180043180

Methods and apparatus for the inactivation of infectious agents in, on or around a catheter residing in a patient's body cavity. The method comprises a coupling adapter for facilitating the transmission of non-ultraviolet sterilizing electromagnetic radiation (emr) substantially axially along an optical element into the catheter body. Through delivery of the sterilizing emr to particular areas of highest infection, the ...
Vacuum assisted skin penetrating appliance with external interface
Viaderm, Llc
February 15, 2018 - N°20180043069

A system and method for a modular external interface for a skin penetrating appliance is provided. The modular device prevents internalization of bacteria, other infectious agents, or other unwanted materials from entering the access point for a catheter, steinman pin, kirschner wires, or other percutaneous instruments. The modular external interface provides for the hermaticity in the vicinity of the skin-appliance ...
Glucocerebroside treatment of disease
Enzo Therapeutics, Inc.
February 15, 2018 - N°20180042959

The present invention provides a method for the treatment of immune mediated or immune related diseases or disorders, infectious diseases, metabolic disorders and cancer in mammalian subjects. This method comprises the administration of a naturally occurring, mammalian intermediary metabolite or t cell receptor ligand, preferably a glucosylceramide, to a mammalian subject. In a preferred embodiment, such mammalian subjects are human ...
Infectious Patent Pack
Download 268+ patent application PDFs
Infectious Patent Applications
Download 268+ Infectious-related PDFs
For professional research & prior art discovery
  • 268+ full patent PDF documents of Infectious-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Multiplex immuno screening assay
Institut Pasteur
February 08, 2018 - N°20180038852

The present invention provides kits and assay methods for the early detection of pathogens, precise identification of the etiologic agent, and improved disease surveillance. More specifically, the present invention discloses an immunoassay leading to the rapid and simultaneous detection of antibodies to a wide range of infectious pathogens in biological fluids of infected patients. This immunoassay involves the covalent and ...
Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing
Fred Hutchinson Cancer Research Center
February 08, 2018 - N°20180037953

Methods are provided for predicting a subject's infection status using high-throughput t cell receptor sequencing to match the subject's tcr repertoire to a known set of disease-associated t cell receptor sequences. The methods of the present invention may be used to predict the status of several infectious agents in a single sample from a subject. Methods are also provided for ...
Capsid-modified raav vectors and methods of use
University Of Florida Research Foundation, Incorporated
February 08, 2018 - N°20180036428

Disclosed are tyrosine-modified raav vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant raav vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of raav vectors.
Molecular antigen array
Kuros Biosciences Ag
February 08, 2018 - N°20180036399

The present invention is related to the fields of molecular biology, virology, immunology and medicine. The invention provides a composition comprising an ordered and repetitive antigen or antigenic determinant array. The invention also provides a process for producing an antigen or antigenic determinant in an ordered and repetitive array. The ordered and repetitive antigen or antigenic determinant is useful in ...
Anti-pd-1 antibodies
Aduro Biotech Holdings, Europe B.v.
February 01, 2018 - N°20180030137

The present invention relates to anti-pd-1 antibodies, as well as use of these antibodies in the treatment of diseases such as cancer and infectious disease. These antibodies have cdrs as provided in the enclosed sequences. Also part of the invention are nucleic acids encoding these antibodies, expression vectors comprising such nucleotide sequences and host cells that comprise said nucleotide sequences ...
Icos binding proteins
Centre National De La Recherche Scientifique (cnrs)
February 01, 2018 - N°20180030136

The present invention relates to an icos binding protein or antigen binding portion thereof that is an agonist to human icos and does not induce complement, adcc, or cdc when placed in contact with a t cell in vivo and methods of treating cancer, infectious disease and/or sepsis with said icos binding protein or antigen binding portion thereof. Further ...
Immunotherapeutic vaccine and antibody combination therapy
Transgene Sa
February 01, 2018 - N°20180028626

The present invention relates to a combination product, composition(s) and kit of parts comprising at least (i) a therapeutic vaccine and (ii) one or more immune checkpoint modulator(s). The present invention also concerns a method for treating a proliferative or an infectious disease as well as a method for eliciting or stimulating and/or re-orienting an immune response, ...
Infectious Patent Pack
Download 268+ patent application PDFs
Infectious Patent Applications
Download 268+ Infectious-related PDFs
For professional research & prior art discovery
  • 268+ full patent PDF documents of Infectious-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Medicinal solution to be continuously or pulse-delivered to the eye for treating ophthalmological conditions/maladies
February 01, 2018 - N°20180028533

The present invention relates generally to a medicinal solution, and more particularly to a medicinal solution which is to be continuously or pulse-delivered for the purpose of treating various ocular diseases, conditions, or maladies, such as keratoconus, infectious keratitis, severe inflammatory conditions, and ocular surface neoplasia. In particular, the medicinal solution comprises the combination of a medication for treating one ...
Polymer-based antimicrobial compositions and methods of use thereof
Exion Labs Inc.
February 01, 2018 - N°20180028431

Provided is a polymer-based antimicrobial composition that is non-toxic, water soluble, and that mitigates the transmission of infectious diseases from surfaces. The composition comprises a cationic polymer, at least one adhesion promoter, optionally organic and/or inorganic particles that are photocatalytically active in visible light, and a carrier, in which the components of the composition are not covalently bound to ...
Immune regulatory oligonucleotide (iro) compounds to modulate toll-like receptor based immune response
Idera Pharmaceuticals, Inc.
January 25, 2018 - N°20180023085

The invention provides novel immune regulatory oligonucleotides (iro) as antagonist of tlrs and methods of use thereof. These iros have unique sequences that inhibit or suppress tlr-mediated signaling in response to a tlr ligand or tlr agonist. The methods may have use in the prevention and treatment of cancer, an autoimmune disorder, airway inflammation, inflammatory disorders, infectious disease, skin disorders, ...
Employing human adipose-derived stem cells to propagate serum-derived hepatitis c virus and use thereof
Frontier Bio-drug Development Limited
January 25, 2018 - N°20180023058

Hepatitis c virus replication at extrahepatic sites has been suggested; however, complete viral replication has only been confirmed in hepatocytes. Here we show that human adipogenic dlk-1+ stem cells (hadsc) freshly isolated from hcv-infected individuals contained viral transcripts, replication intermediates and viral antigens in vivo, and viral transcripts increased in supernatants upon prolonged ex vivo culture. Furthermore, naive hadsc isolated ...
Method for preparing antigen-specific cytotoxic t-cells by using activated b-cells and use thereof
Seoul National University R&db Foundation
January 25, 2018 - N°20180023054

Disclosed in the present application are: a method for preparing in vitro/ex vivo antigen-specific cytotoxic t-cells by using b cells treated with biological response modifier; and a use thereof. The cytotoxic t-cells prepared by the method of the present application can be used advantageously for treating infectious disease and cancer and the like.
Chimeric and humanized anti-histone antibodies
Immunomedics, Inc.
January 25, 2018 - N°20180022796

The present invention concerns chimeric or humanized antibodies or antigen-binding fragments thereof that comprise specific cdr sequences, disclosed herein. Preferably, the antibodies or fragments comprise specific heavy and light chain variable region sequences disclosed herein. More preferably, the antibodies or fragments also comprise specific constant region sequences, such as those associated with the ng1m1,2 or km3 allotypes. The antibodies ...
Targeted conjugates encapsulated in particles and formulations thereof
Tarveda Therapeutics, Inc.
January 25, 2018 - N°20180021454

Particles, including nanoparticles and microparticles, and pharmaceutical formulations thereof, containing conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety via a linker have been designed which can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the conjugates, the particles, and the formulations thereof are ...
Methods of treating hematological disorders, solid tumors, or infectious diseases using natural killer cells
Anthrogenesis Corporation
January 25, 2018 - N°20180021378

Provided herein are methods of treating a hematological disorder, a solid tumor, or an infectious disease in a subject in need thereof using natural killer cells in combination with a second agent, or using natural killer cells with genetic modifications for target specificity and/or homing specificity.