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Infectious Diseases patents

      

This page is updated frequently with new Infectious Diseases-related patent applications.




 Methods for diagnosing infectious diseases using adsorption media patent thumbnailMethods for diagnosing infectious diseases using adsorption media
The present invention provides an in vitro method for concentrating infectious pathogens found in a biological sample obtained from an individual who is suspected of being infected with the pathogens. Provided herein is also an in vitro method for reducing or eliminating blood cells from a sample obtained from an individual suspected to being infected with an infectious pathogen.
Exthera Medical Corporation


 A chimeric peptide that interacts with cell membrane gangliosides patent thumbnailA chimeric peptide that interacts with cell membrane gangliosides
The invention relates to a chimeric peptide displaying the ganglioside-binding properties of both α-synuclein and β-amyloid peptide. Such peptide is useful in preventing or treating any condition which involves gangliosides as cell surface receptor sites, including neurodegenerative disorders, infectious diseases, or tumors..
Universite D'aix-marseille


 Antimicrobial peptides patent thumbnailAntimicrobial peptides
A novel antimicrobial peptide includes at least eight successive amino acids, the peptide exhibiting a sequence having the following formula: ter1-x1—b1—x2—b2—x3—z1—z2—x4-ter2. The peptide can moreover also have modified termini.
Robert Bosch Gesellschaft FÜr Medizinische Forschung Mbh


 Toll-like receptor 2 agonists and vaccines and uses thereof patent thumbnailToll-like receptor 2 agonists and vaccines and uses thereof
The present invention relates to toll-like receptor 2 (tlr2) agonists, in particular, to tlr2-activating lipoproteins, and more particularly to tlr2-activating lipopeptides derived from the bacteria bordetella pertussis. The invention further extends to the use of said tlr2-activating lipoproteins as a therapeutic or as part of a vaccine composition in the treatment and prevention of infectious diseases, cancer or allergic diseases..
The Provost, Fellows, Foundation Scholars & The Other Members Of Board, Of The College Of The Holy


 Methionine aminopeptidase inhibitors for treating infectious diseases patent thumbnailMethionine aminopeptidase inhibitors for treating infectious diseases
The present invention relates to methods for treating an infectious disease in a subject in need thereof via administration of a therapeutically effective amount of compounds described herein. The methods may utilize particular compounds, for example, a quinoline, a hydrazone, a quinone, or a pyrimidine derivative thereof or a pharmaceutical salt thereof..
Texas Southern University


 Methionine aminopeptidase inhibitors for treating infectious diseases patent thumbnailMethionine aminopeptidase inhibitors for treating infectious diseases
The present invention relates to methods for treating an infectious disease in a subject in need thereof via administration of a therapeutically effective amount of compounds described herein. The methods may utilize particular compounds, for example, a quinoline, a hydrazone, a quinone, or a pyrimidine derivative thereof or a pharmaceutical salt thereof..
The Board Of Regents Of The University Of Texas System


 Methionine aminopeptidase inhibitors for treating infectious diseases patent thumbnailMethionine aminopeptidase inhibitors for treating infectious diseases
The present invention relates to methods for treating an infectious disease in a subject in need thereof via administration of a therapeutically effective amount of compounds described herein. The methods may utilize particular compounds, for example, a quinoline, a hydrazone, a quinone, or a pyrimidine derivative thereof or a pharmaceutical salt thereof..
The Board Of Regents Of The University Of Texas System


 Pyrrolo[3,2-d]pyrimidine derivatives as inducers of human interferon patent thumbnailPyrrolo[3,2-d]pyrimidine derivatives as inducers of human interferon
Wherein r1 is hydrogen, methyl or —(ch2)2or3, r2 is methyl or —(ch2)2or4, or r1 and r2, together with the nitrogen atom to which they are attached, are linked to form a 5- or 6-membered heterocyclyl wherein the 6-membered heterocyclyl is optionally substituted by two hydroxy substituents; r3 and r4 are each independently hydrogen or methyl; and n is an integer having a value of 5 or 6, are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment or prevention of various disorders, for example the treatment or prevention of allergic diseases and other inflammatory conditions, for example allergic rhinitis and asthma, infectious diseases and cancer, and may also be useful as vaccine adjuvants..

 Methods and pharmaceutical compositions for the treatment of diseases mediated by the nrp-1/obr complex signaling pathway patent thumbnailMethods and pharmaceutical compositions for the treatment of diseases mediated by the nrp-1/obr complex signaling pathway
The present invention relates to methods and pharmaceutical compositions for the treatment of diseases mediated by the nrp-1/obr complex signaling pathway. In particular, the present invention relates to a method for treating a disease selected from the group consisting of cancers, obesity and obesity related diseases, anorexia, autoimmune diseases and infectious diseases in a subject in need thereof comprising administering the subject with a therapeutically effective amount of an antagonist of the nrp-1/obr signaling pathway..
Universite De Bourgogne


 Method for treating infectious diseases using emissive energy patent thumbnailMethod for treating infectious diseases using emissive energy
The present invention relates to the treatment of infectious diseases, specifically by extracorporeally eradicating the pathogen. This invention comprises methods for the extracorporeal treatment of infectious diseases that will remove infectious pathogens (leukemia cells, bacteria, viruses, or fungi causing a septicemia, metastatic cancer cells, target protein, viruses, parasites, fungi and prions) in humans by targeting such pathogens with a laser or other high-energy source of emissive radiation.
Marv Enterprises, Llc


Compositions having means for targeting at least one antigen to dendritic cells

A composition that can be used as a vaccine containing means for targeting at least one antigen to dendritic cells and as adjuvants a granulocyte macrophage colony stimulating factor and a cpg oligodeoxynucleotide and/or a cpg-like oligodeoxynucleotide. This composition can used to treat cancers, infectious diseases caused by bacterial, viral, fungal, parasitic or protozoan infections, allergies and/or autoimmune diseases..
Universite Paris Descartes

Novel bacteriophage and composition comprising same

The present invention relates to a novel bacteriophage Φcj25 (kccm11463p) and a composition comprising the same as an active ingredient. In addition, the present invention relates to a method for preventing and/or treating infectious diseases caused by avian pathogenic escherichia coli (apec) of birds by using the bacteriophage Φcj25 (kccm11463p) or the composition..
Cj Cheiljedang Corporation

Method for treating infectious diseases using a composition comprising plasma-derived immunoglobulin m (igm)

Compositions and methods of the present invention prevent, inhibit or reduce the toxic effects of proteins and toxins secreted from microbes. A method for neutralizing microbial protein products in a subject comprises administering a composition to the subject, said composition comprising plasma-derived igm and optionally one or more excipients in a pharmaceutical carrier, wherein the composition is administered in an amount effective to neutralize the microbial protein products..
Grifols Worldwide Operations Limited

Nkt cell ligands and methods of use

Alpha-glycosylceramide compounds capable of activating nkt cells and compositions thereof are disclosed. Methods for activating nkt cells, methods of stimulating an immune response in a subject, and methods of treating cancer, infectious diseases, autoimmune diseases and disorders, or allergy diseases or disorders with the compounds and compositions are also disclosed..
Brigham Young Unversity

Novel macrocyclic compounds

The present invention relates to novel macrocyclic compounds of general formula (i) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (i)..
Bayer Pharma Aktiengesellschaft

Methionine analogs and methods of using same

Provided are methionine analogs which may be useful for inhibiting protein synthesis, inhibiting microbial growth and/or treating infectious diseases. In some instances, the analogs exhibit bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and/or antiviral properties.
Bioxiness Pharmaceuticals, Inc.

Vaccine composition

An intraorally administrable vaccine composition useful to be a preventive or therapeutic agent for infectious diseases, and effectively induces a systemic immune response or a mucosal immune response is provided. A vaccine composition for administration to the oral cavity of a human or an animal, the vaccine composition containing at least one antigen derived from an infectious disease, and at least one selected from the group consisting of a toll-like receptor 4 (tlr4) agonist, a toll-like receptor 2/6 (tlr2/6) agonist, and cyclic dinucleotide, or a derivative or salt thereof..
Nitto Denko Corporation

Salts and prodrugs of 1-methyl-d-tryptophan

Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.. .
Newlink Genetics, Corp.

Disubstituted 5-fluoro pyrimidine derivatives containing a sulfondiimine group

The present invention relates to 5-fluoro pyrimidine derivatives containing a sulfondiimine group of general formula (i) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (i)..
Bayer Pharma Aktiengesellschaft

Combination of vaccination and ox40 agonists

The present invention relates to a vaccine/agonist combination comprising an rna vaccine comprising at least one rna comprising at least one open reading frame (orf) coding for at least one antigen and a composition comprising at least one ox40 agonist. The present invention furthermore relates to a pharmaceutical composition and a kit of parts comprising the components of such a vaccine/agonist combination.
Curevac Ag

Inhibition of hypoxia-inducible factor activity with carica papaya extracts

An extract of carica papaya leaves obtained from a plant of age six months and younger from the date of germination of the seed is used as an inhibitor of hif to effectively block hypoxia-inducible factor (hif) function and methods of use thereof. More specifically it relates to the use of the carica papaya plant extract to eliminate unwanted cells by inhibiting hif in the prevention and treatment of hypoxia-related conditions and diseases such as inflammatory diseases, vascular diseases, cancer and infectious diseases.
Universiti Putra Malaysia

Benzazepine dicarboxamide compounds

Wherein r1 to r4 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are tlr agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft rejection, graft-versus-host disease, immunodeficiencies, and infectious diseases..

Methods and compositions for treating cancer and infectious diseases

The invention relates to compositions comprising a cd4 lymphocyte depleting agent; and methods of using the compositions to treat, prevent, reduce the severity of and/or slow the progression of a condition in a subject. The invention also relates to use of combinations of a cd4 lymphocyte depleting agent and at least one additional agent to treat, prevent, reduce the severity of and/or slow the progression of a condition in a subject.
Cedars-sinai Medical Center

Probiotics for use in expecting female mammals for enhancing the immunity of their offspring

The present invention relates to the use of probiotic on expecting female mammals to boost the immune status of an offspring. The use can induce an enhanced response of the offspring after birth to an infectious antigenic exposure.
Nestec S.a.

Compositions and methods for modulating an immune response

Described herein are compositions for increasing il-12 production comprising igg or a fragment thereof or a variant thereof and uses of said compositions for treating cancer and infectious diseases. Also described herein are compositions for decreasing il-12 production comprising an agent that inhibits signaling mediated by interaction between fcrn and igg and uses of said compositions for treating autoimmune diseases.
The Brigham And Women's Hospital, Inc.

5-fluoro-n-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group

The present invention relates to 5-fluoro-n-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group of general formula (i) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (i)..
Bayer Pharma Aktiengesellschaft

Method for producing dry extracts

The invention relates to a method for producing dry extracts of plants and to pharmaceutical preparations containing the same, more particularly phytopharmaceuticals, which contain at least one ethanolic/aqueous extract of a plant (drug), the plants being selected from the group consisting of: rumicis herba; verbena officinalis; sambucus nigra; primula veris; and gentiana lutea and mixtures thereof. The invention further relates to a pharmaceutical for treating inflammatory and/or infectious diseases of the nose and throat area and/or the nasal sinuses, as well as the use thereof..
Bionorica Se

Methods for preventing or treating infectious diseases caused by extracellular microorganisms, including antimicrobial-resistant strains thereof, using gallium compounds

The present invention relates to methods for preventing or treating infectious diseases caused by extracellular microorganisms, such as bacteria and fungi, by systemically administering to a patient a compound containing gallium. The extracellular microorganisms targeted by the present methods include methicillin-resistant staphylococcus aureus (mrsa), vancomycin-resistant enterococcus faecalis (vre), e.
Mount Sinai School Of Medicine

Human monoclonal antibodies to programmed death ligand 1 (pd-l1)

The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies that specifically hind to pd-l1 with high affinity. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided.
E.r. Squibb & Sons, L. L. C.

Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain

Compounds of formula i: or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein ring a, ring c and x are as defined herein, are inhibitors of trka kinase and are useful in the treatment of diseases which can be treated with a trka kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.. .
Array Biopharma Inc.

Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors

Compounds of formula i or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein ring a, ring c and x are as defined herein, are inhibitors of trka kinase and are useful in the treatment of diseases which can be treated with a trka kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.. .
Array Biopharma Inc.

Vstm5 polypeptides and uses thereof as a drug for treatment of cancer, infectious diseases and immune related diseases

This invention relates to vstm5 proteins, soluble molecules and fusions thereof which are suitable targets for drug development and for treatment of immune related disorders, immunotherapy, treatment of cancer, infectious disorders and/or sepsis.. .
Compugen Ltd.

Parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same

There may be provided compositions of lipophilic pharmaceutical agents with improved solubility and stability. For example, there may be provided a non-aqueous composition that comprises a lipophilic pharmaceutical agent, and an amphiphilic polymeric solvent such as peg400 but essentially free of organic solvents and non-solubilized particles.

Method and system for integrating infectious disease data with transaction data

A method for tracking existence and spread of infectious diseases using transaction data includes: storing transaction data entries, each entry including data related to a payment transaction including a transaction time, geographic location, and transaction data; receiving disease data indicating an infectious disease in a geographic area, the data including an infection period of time; identifying a first subset of transaction data entries including the geographic location in the received disease data and where the transaction time is within the infection period of time; identifying a second subset of transaction data entries that include a geographic location in a shared geographic area where the included transaction data corresponds to the transaction data included in the transaction data entries in the first subset; and transmitting an infection notification, the notification including at least the shared geographic area.. .
Mastercard International Incorporated

Immunomodulatory agents

The invention provides antibodies that specifically bind to pd-l1 and fusion molecules comprising pd-l1 binding proteins constructed with an il15 receptor-binding domain, nucleic acid molecules encoding the same, and therapeutic compositions thereof. The agents inhibit pd-l1-mediated immunosuppression and enhance cell and cytokine mediated immunity for the treatment of neoplastic and infectious diseases..
Kadmon Corporation, Llc

Molecular constructs for treating infectious diseases

The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed..
Immunwork Inc.

Macrocyclic inhibitors of the pd-1/pd-l1 and cd80(b7-1)/pd-l1 protein/protein interactions

The present disclosure provides novel macrocyclic peptides which inhibit the pd-1/pd-l1 and pd-l1/cd80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.. .
Bristol-myers Squibb Company

Synthesis of tetracyclines and analogues thereof

The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics.
President And Fellows Of Harvard College

Compounds, compositions and associated methods comprising 3-aryl quinolines

Compounds, compositions and methods useful for treating infectious diseases are provided. In particular, 3-aryl quinoline compounds, their synthesis, pharmaceutical compositions thereof and methods of treating infectious diseases such as malaria, are disclosed..
The United States Government As Represented By The Department Of Veterans Affairs

Molecular constructs with targeting and effector moieties for treating infectious diseases

The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed..
Immunwork Inc.

Peptide core-based multi-arm linkers for treating infectious diseases

The present disclosure provides various molecular constructs having a targeting element and an effector element. Methods for treating various diseases using such molecular constructs are also disclosed..
Immunwork Inc.

Monobactams and methods of their synthesis and use

Described herein are monobactam antibiotics of formula (i), (i′), (ii), and (ii′), along with methods and intermediates for preparing these compounds. Pharmaceutical compositions and methods of treating infectious diseases using the monobactams are also provided..
President And Fellows Of Harvard College

Proline-rich peptides protective against s. pneumoniae

The invention relates to lipopeptides consisting of a peptide chain comprising a parallel coiled-coil domain, a proline-rich peptide antigen, and a lipid moiety, all covalently linked, which aggregate to synthetic virus-like particles. Proline-rich peptide antigens considered contain negatively and positively charged amino acid, and at least 15% of the amino acids are proline.
UniversitÄt ZÜrich

Methods of t cell epitope profiling, making t cell compositions, and treating diseases

Disclosed herein is a method of detecting antigen specific t cells in a sample isolated from a subject and mapping immunostimulatory epitopes of the antigen. Such methods may be used in methods of making antigen specific t cell compositions, e.g., for the treatment of diseases such as cancer, infectious diseases and autoimmune disorders..
Opexa Therapeutics, Inc.

Non-coding rna of salmonella and identification and use thereof

The present invention provides salmonella non-coding rna and the identification and application thereof. In particular, the present invention proves through experiments that a salmonella bacterium delivers non-coding rnas (ncrnas) encoded by the bacterium itself into a host cell, generates milrnas similar to micrornas by means of a microrna splicing system in the cell, regulates the immune system with the milrnas, and further protects the salmonella bacterium from being cleared by the host.
Jiangsu Micromedmark Biotech Co. Ltd.

Opsonic and protective monoclonal antibodies against gram-positive pathogens

The present invention in the fields of immunology and infectious diseases relates to opsonic and protective antibodies that are specific for gram-positive bacteria, particularly to carbohydrate structures exposed on the surface of the bacteria. The invention includes monoclonal and chimeric antibodies, as well as fragments, regions and derivatives thereof.
Albert-ludwigs-universitÄt Freiburg

Anti-infective properties of antifreeze protein

As microbial drug-resistance increases, there is a critical need for new classes of compounds to combat infectious diseases. The ixodes scapularis tick antifreeze glycoprotein, iafgp, functions as an anti-infective agent against diverse bacteria including methicillin-resistant staphylococcus aureus.
Yale University

Polynucleotide, polypeptide with immunosuppressive activity, expression cassette, expression vector, host cell, pharmaceutical composition, methods for producing a polypeptide with immunosuppressive activity and for preventing or treating conditions that require immunosuppression, and use of a polypeptide

This invention refers to polynucleotides and non-hemorrhagic and non-immunogenic polypeptides of selective immunosuppressive activity on production of antibodies to antigens of different natures. The polypeptides described herein are useful for preparing pharmaceutical compositions for prevention or treatment of conditions that require immunosuppression, preferably, inflammatory, autoimmune, allergic and infectious diseases and rejection to transplanted organs..
FundaÇÃo Butantan

Novel antifungal oxodihydropyridinecarbohydrazide derivative

The present invention relates to novel oxodihydropyridinecarbohydrazide derivatives with excellent antifungal activities, an antifungal composition containing the same, and its use for the prevention and treatment of fungal infectious diseases. The oxodihydropyridinecarbohydrazide derivatives of the present invention have excellent antifungal and fungicidal activities, and thus will be useful for the prevention and treatment of various fungal infections by candida spp., aspergillus spp., cryptococcus neoformans and trichophyton spp., etc.
Daewoong Pharmaceutical Co., Ltd.

Novel compounds useful for the treatment of bacterial infectious diseases

Novel compounds of the invention may be prepared as a pharmaceutical composition, and may be useful in the treatment of infectious diseases, in particular bacterial infectious diseases. The compounds may be active against a specific enzyme in the bacterial dna replicative process, dna polymerase iiie..

Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors

Compounds of formula (i): or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where r1, r2, ra, rb, rc, rd, x, ring b, and ring c are as defined herein, and wherein ring b moiety and the nh—c(═x)—nh moiety are in the trans configuration, are inhibitors of trka kinase and are useful in the treatment of diseases which can be treated with a trka kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.. .
Array Biopharma Inc.

Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors

Compounds of formula i: or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where r1, r2, ra, rb, rc, rd, x, ring b, and ring c are as defined herein, and wherein ring b moiety and the nh—c(═x)—nh moiety are in the trans configuration, are inhibitors of trka kinase and are useful in the treatment of diseases which can be treated with a trka kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome.. .
Array Biopharma Inc.



Infectious Diseases topics:
  • Infectious Disease
  • Infectious
  • Infectious Diseases
  • Immune Response
  • Immune Diseases
  • Immune Disease
  • Autoimmune
  • Autoimmune Disease
  • Autoimmune Diseases
  • Immunogenic
  • Nucleotide
  • Vitamin B12
  • Vitamin B1
  • Recombinant
  • Vaccination


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    This listing is a sample listing of patent applications related to Infectious Diseases for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Infectious Diseases with additional patents listed. Browse our RSS directory or Search for other possible listings.


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