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Infectious Diseases

Infectious Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Activation of adaptive immune processes for the treatment of cancers and infectious diseases
Susavion Biosciences, Inc.
October 12, 2017 - N°20170290922

Polypeptides, such as a multi-valent polypeptide designated svd2, useful in pharmaceutical compositions for stimulation of the adaptive arm of the immune system. Svd2 demonstrated in vivo activity in a syngeneic mouse model. Svd2 is biologically active at nanomolar concentrations. These properties are believed to result as a consequence of the ability of svd2 to cross-link cell-surface receptors.
Pyrazolopyrimidine compounds
Susavion Biosciences, Inc.
October 12, 2017 - N°20170290910

Wherein r1 is n-c1-6alkyl or c1-2alkoxyc1-2alkyl-, r2 is halo, oh or c1-3alkyl, m is an integer having a value of 4, 5, 6 or 7, n is an integer having a value of 0, 1, 2 or 3, and p is an integer having a value of 0, 1 or 2, are inducers of human interferon. Compounds which induce human interferon may be ...
Immunomodulators
Bristol-myers Squibb Company
October 05, 2017 - N°20170283463

The present disclosure provides novel macrocyclic peptides which inhibit the pd-1/pd-l1 and pd-l1/cd80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
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Infectious Diseases Patent Applications
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Macrocyclic compounds as trk kinase inhibitors
Array Biopharma, Inc.
October 05, 2017 - N°20170283435

Compounds of formula i: and pharmaceutically acceptable salts thereof, wherein ring a, ring b, w, m, d, r2, r2a, r3, r3a, and z are as defined herein, are inhibitors of trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Benzazepine sulfonamide compounds
Array Biopharma, Inc.
September 28, 2017 - N°20170275253

Wherein r4 or r5 is —so2—nr7r8 and r1 to r8 and y are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are tlr agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft ...
Production method for pluripotent stem cells having antigen-specific t cell receptor gene
Array Biopharma, Inc.
September 21, 2017 - N°20170267972

(2) inducing t cell progenitors or mature t cells from the pluripotent stem cells provided in step (1). Pluripotent stem cells may preferably be ips cells. The human pluripotent stem cells bearing a t cell receptor specific for an antigen may be prepared by inducing ips cells from a t cell having the desired antigen specificity or by introducing genes encoding the ...
Infectious Diseases Patent Pack
Download 108+ patent application PDFs
Infectious Diseases Patent Applications
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For professional research & prior art discovery
inventor
  • 108+ full patent PDF documents of Infectious Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Pharmaceutical formulations that form gel in situ
Iview Therapeutics, Inc.
September 21, 2017 - N°20170266294

The present invention provides aqueous formulations containing an anti-infection agent, a biocompatible polysaccharide, an osmotic pressure regulator, a ph regulator, and water, wherein a gel containing the therapeutic agent is formed in situ upon instillation of the formulations onto the skin and a body cavity of a subject. The formulations of this invention are useful for treating infectious diseases of ...
A novel synergistic herbal formulation for degenerative disease cardiovascular diseases, autoimmune, inflammatory and metabolism disorder ...
Iview Therapeutics, Inc.
September 21, 2017 - N°20170266247

The present invention relates to a novel synergistic herbal formulation for degenerative disease, cardiovascular diseases, autoimmune, inflammatory and infectious diseases and metabolism disorder etc. Of man, animal and plants more particularly, the present invention relates to the herbal formulation for degenerative disease, cardiovascular diseases, autoimmune, inflammatory and infectious diseases etc which is prepared by using preparation of pongamia pinnata, dalbergia ...
Macrocyclic inhibitors of the pd-1/pd-l1 and cd80(b7-1)/pd-l1 protein/protein interactions
Bristol-myers Squibb Company
September 14, 2017 - N°20170260237

The present disclosure provides novel macrocyclic peptides which inhibit the pd-1/pd-l1 and pd-l1/cd80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
Method for the detection of antigen presentation
Deutsches Krebsforschungszentrum Stiftung Des öffentlichen Rechts
September 07, 2017 - N°20170254803

The present invention pertains to a method for detecting antigen presentation via antigen presenting molecules such as major histocompatibility complex (mhc) class i or ii. The invention deploys a first binding agent specific for the antigen epitope and a second binding agent specific for the antigen presenting molecule. The binding agents of the invention are coupled to proximity probes which ...
Immunomodulators
Bristol-myers Squibb Company
September 07, 2017 - N°20170252432

The present disclosure provides novel macrocyclic compounds which inhibit the pd-1/pd-l1 and pd-l1/cd80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
Method and compositions for inducing differentiation of myeloid derived suppressor cell to treat cancer and ...
Ose Immunotherapeutics
August 31, 2017 - N°20170247464

The present invention pertains to the field of immunoterapy. More specifically, the present invention provides a method for differentiating myeloid-derived suppressor cells (mdsc) into non suppressive cells, by administering a compound blocking the interaction between sirpa and cd47 to a patient in need thereof in order to reduce mdsc-induced immunodepression and consequently allow appropriate immune responses in cancers, infectious diseases, ...
Anti-tim-3 antibodies
Agency For Science, Technology And Research
August 24, 2017 - N°20170240633

Anti-tim-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer, infectious diseases, or t-cell dysfunctional disorders. Bispecific antibodies against tim-3 and other targets are also disclosed, with preferred embodiment of a bispecific antibody against tim-3 and cd3.
Infectious Diseases Patent Pack
Download 108+ patent application PDFs
Infectious Diseases Patent Applications
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inventor
  • 108+ full patent PDF documents of Infectious Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Fluorinated benzofuranyl-pyrimidine derivatives containing a suflone group
Bayer Pharma Aktiengesellschaft
August 10, 2017 - N°20170226092

The present invention relates to fluorinated benzofuranyl-pyrimidine derivatives containing a sulfone group of general formula (i) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyperproliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful ...
An antagonistic pd-1 aptamer and its applications in cancer therapy related applications
National Taiwan University
August 03, 2017 - N°20170218369

Aptamers that bind to and antagonize pd-1 and uses thereof in promoting t cell proliferation, treating cancer or infectious diseases such as hiv infection.
Novel compounds for the treatment of infectious diseases
National Taiwan University
August 03, 2017 - N°20170217990

Wherein r1, r2, r3, r4, r5 and r6 are as described herein, and their prodrugs or pharmaceutically acceptable salt, enantiomer or diastereomer thereof, and compositions including the compounds and methods of using the compounds.
4-aryl-n-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group
Bayer Intellectual Property Gmbh
August 03, 2017 - N°20170217949

The present invention relates to 4-aryl-n-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (i) or (ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate ...
Fluorinated benzofuranyl-pyrimidine derivatives containing a sulfoximine group
Bayer Pharma Aktiengesellschaft
August 03, 2017 - N°20170217938

The present invention relates to fluorinated benzofuranyl-pyrimidine derivatives containing a sulfoximine group of general formula (i) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful ...
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as trka kinase inhibitors
Array Biopharma Inc.
August 03, 2017 - N°20170217936

Compounds of formula i: or stereoisomers, tautomers, or pharmaceutically acceptable salts, or solvates or prodrugs thereof, where r1, r2, ra, rb, rc, rd, x, y, b, and ring c are as defined herein, and wherein the y—b moiety and the nh—c(═x)—nh moiety are in the trans configuration, are inhibitors of trka kinase ...
Vaccine pharmaceutical composition for transdermal administration
Nitto Denko Corporation
August 03, 2017 - N°20170216431

The present invention provides a vaccine pharmaceutical composition for transdermal administration which is safe, usable as a prophylactic or therapeutic agent for cancer or infectious diseases, and capable of safely and effectively inducing a systemic immune response. It can be administered to a human or animal skin, the vaccine pharmaceutical composition including: a lipopolysaccharide or its salt derived from at ...
Automated immunoanalyzer system for performing diagnostic assays for autoimmune and infectious diseases
Hycor Biomedical, Llc
July 27, 2017 - N°20170212110

A quantitative method for diagnosing an autoimmune disease or an infectious disease comprising performing an automated diagnostic assay, comprising: incubating a capture reagent with a streptavidin-coated medium to form a solid phase complex, wherein the capture reagent is a biotinylated autoantigen or infectious disease antigen; washing the solid phase complex to remove excess capture reagent; incubating the solid phase complex ...
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