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Infectious Disease

Infectious Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Phosphoramidite synthones for the synthesis of self-neutralizing oligonucleotide compounds
Zata Pharmaceuticals, Inc.
November 09, 2017 - N°20170320902

Compositions and compounds having nucleoside phosphoramidites, and methods of making the same are provided. The compounds can also have one or more amino groups that each can be positively charged. The compounds described permit facile attachment of certain neutralizing moieties with positive charges at their terminal ends on the backbones of oligonucleotides. The compounds can be used for the treatment ...
Icos binding proteins
Zata Pharmaceuticals, Inc.
November 02, 2017 - N°20170313777

The present invention relates to an icos binding protein or antigen binding portion thereof that is an agonist to human icos and does not induce complement, adcc, or cdc when placed in contact with a t cell in vivo and methods of treating cancer, infectious disease and/or sepsis with said icos binding protein or antigen binding portion thereof. Further ...
Targeted conjugates and particles and formulations thereof
Zata Pharmaceuticals, Inc.
November 02, 2017 - N°20170312245

Nanoparticles and microparticles, and pharmaceutical formulations thereof, containing conjugates of an active agent such as a therapeutic, prophylactic, or diagnostic agent attached to a targeting moiety, such as a somatostatin receptor binding moiety, via a linker have been designed. Such nanoparticles and microparticles can provide improved temporospatial delivery of the active agent and/or improved biodistribution. Methods of making the ...
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Infectious Disease Patent Applications
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  • 152+ full patent PDF documents of Infectious Disease-related inventions.
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Anti-tim-3 antibodies
Agency For Science, Technology And Research
October 26, 2017 - N°20170306016

Anti-tim-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer or infectious disease or t-cell dysfunctional disorders. Bispecific antibodies against tim-3 and other targets are also disclosed, with a preferred embodiment of a bispecific antibody against tim-3 and cd3.
Cross reactive siglec antibodies
Innate Pharma
October 26, 2017 - N°20170306014

This invention relates to agents that bind multiple siglecs, including antibodies that neutralize the inhibitory activity of multiple siglec-7 and siglec-9 in lymphocytes. Such agents can be used for the treatment of cancers or infectious disease.
14-membered ketolides and methods of their preparation and use
President And Fellows Of Harvard College
October 26, 2017 - N°20170305953

Provided herein are methods of preparing new 14-membered ketolides via coupling of an eastern and western half moiety, followed by macro-cyclization, and optional functionalization. Intermediates in the synthesis of these ketolides including the eastern and western halves are also provided. Pharmaceutical compositions and methods of treating infectious diseases and inflammatory conditions using these ketolides are also provided.
Infectious Disease Patent Pack
Download 152+ patent application PDFs
Infectious Disease Patent Applications
Download 152+ Infectious Disease-related PDFs
For professional research & prior art discovery
inventor
  • 152+ full patent PDF documents of Infectious Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Formulations of methionine aminopeptidase inhibitors for treating infectious diseases
Texas Southern University
October 26, 2017 - N°20170304288

Provided herein are formulations and co-solvent formulations and methods for treating an infectious disease utilizing the same. The formulations and co-solvent formulations may comprise a hydroxyquinoline analog or its pharmaceutically acceptable salt, a solvent and at least two surfactants. Also provided are methods of quantitating a hydroxyquinoline analog in a sample via chromatographic/spectrometric measurements.
Deuterated o-sulfated beta lactam hydroxamic acids and deuterated n- sulfated beta lactams
Texas Southern University
October 19, 2017 - N°20170298057

Provided herein are deuterated o-sulfated beta-lactam hydroxamic acids and deuterated n-sulfated beta-lactams, pharmaceutical compositions thereof and methods of treating infectious disease with deuterated compounds or pharmaceutical compositions thereof.
Bacterial topoisomerase inhibitors and use thereof
Texas Southern University
October 19, 2017 - N°20170298004

The present invention provides novel compounds as bacterial topoisomerase inhibitors with antibacterial activity. The present invention also provides pharmaceutical compositions comprising at least one of the compounds and methods of using the compounds and pharmaceutical compositions as antibacterial agents for treating infectious diseases.
Conjugates of cell binding molecules with cytotoxic agents
Texas Southern University
October 19, 2017 - N°20170296663

A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a formula (i), wherein t, l, m, n, r1, r2, r3, r4, r5, r6, r7, r8, r9, r10, r11, r12, and r13 are defined herein, can be used for targeted treatment of cancer, autoimmune disease, and infectious disease.
Liquid formulations of (s)-n-(5-((r)-2-(2,5-difluorophenyl)-pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3...
Texas Southern University
October 19, 2017 - N°20170296544

A liquid formulation of (s)—n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, pharmaceutically acceptable salts thereof, or a combination thereof and the use of the liquid formulation in the treatment of pain, cancer, inflammation, and certain infectious diseases are disclosed.
Activation of adaptive immune processes for the treatment of cancers and infectious diseases
Susavion Biosciences, Inc.
October 12, 2017 - N°20170290922

Polypeptides, such as a multi-valent polypeptide designated svd2, useful in pharmaceutical compositions for stimulation of the adaptive arm of the immune system. Svd2 demonstrated in vivo activity in a syngeneic mouse model. Svd2 is biologically active at nanomolar concentrations. These properties are believed to result as a consequence of the ability of svd2 to cross-link cell-surface receptors.
Pyrazolopyrimidine compounds
Susavion Biosciences, Inc.
October 12, 2017 - N°20170290910

Wherein r1 is n-c1-6alkyl or c1-2alkoxyc1-2alkyl-, r2 is halo, oh or c1-3alkyl, m is an integer having a value of 4, 5, 6 or 7, n is an integer having a value of 0, 1, 2 or 3, and p is an integer having a value of 0, 1 or 2, are inducers of human interferon. Compounds which induce human interferon may be ...
Infectious Disease Patent Pack
Download 152+ patent application PDFs
Infectious Disease Patent Applications
Download 152+ Infectious Disease-related PDFs
For professional research & prior art discovery
inventor
  • 152+ full patent PDF documents of Infectious Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Immunomodulators
Bristol-myers Squibb Company
October 05, 2017 - N°20170283462

The present disclosure provides novel macrocyclic peptides which inhibit the pd-1/pd-l1 and pd-l1/cd80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.
Macrocyclic compounds as trk kinase inhibitors
Array Biopharma, Inc.
October 05, 2017 - N°20170283435

Compounds of formula i: and pharmaceutically acceptable salts thereof, wherein ring a, ring b, w, m, d, r2, r2a, r3, r3a, and z are as defined herein, are inhibitors of trk kinases and are useful in the treatment of pain, cancer, inflammation, neurodegenerative diseases and certain infectious diseases.
Antibodies to tigit
Abmuno Therapeutics Llc
October 05, 2017 - N°20170281764

The invention provides monoclonal antibodies that specifically bind to tigit. The monoclonal antibodies have the capacity for substantial activation of t cells and natural killer cells by inhibiting binding of tigit to cd155. The monoclonal antibodies can be used for treatment of cancer and infectious disease, among other applications.
Benzazepine sulfonamide compounds
Abmuno Therapeutics Llc
September 28, 2017 - N°20170275253

Wherein r4 or r5 is —so2—nr7r8 and r1 to r8 and y are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are tlr agonists and may therefore be useful as medicaments for the treatment of diseases such as cancer, autoimmune diseases, inflammation, sepsis, allergy, asthma, graft ...
Method for analyzing health signal to respond to infectious disease and apparatus thereof
Samsung Electronics Co., Ltd.
September 21, 2017 - N°20170270262

A method and an apparatus for analyzing a biosignal to respond to an infectious disease are provided. An analyzing method involves receiving biosignals of users of terminals and location information of the terminals, determining infectiousness of a condition of a user among the users by analyzing the location information and the biosignals, and transmitting feedback information regarding the infectiousness of ...
Production method for pluripotent stem cells having antigen-specific t cell receptor gene
Samsung Electronics Co., Ltd.
September 21, 2017 - N°20170267972

(2) inducing t cell progenitors or mature t cells from the pluripotent stem cells provided in step (1). Pluripotent stem cells may preferably be ips cells. The human pluripotent stem cells bearing a t cell receptor specific for an antigen may be prepared by inducing ips cells from a t cell having the desired antigen specificity or by introducing genes encoding the ...
Methionine analogs and methods of using same
Bioxiness Pharmaceuticals, Inc.
September 21, 2017 - N°20170267632

Provided are methionine analogs which may be useful for inhibiting protein synthesis, inhibiting microbial growth and/or treating infectious diseases. In some instances, the analogs exhibit bactericidal, antibacterial, anti-infective, antimicrobial, sporicidal, disinfectant, antifungal and/or antiviral properties. Also provided are methods of treatment and methods of preparation, as well as kits and unit dosages.
Pro-drug form (p2pdox) of the highly potent 2-pyrrolinodoxorubicin conjugated to antibodies for targeted therapy ...
Immunomedics, Inc.
September 21, 2017 - N°20170266310

Disclosed are methods, compositions and uses of conjugates of prodrug forms of 2-pyrrolinodoxorubicin (p2pdox) with antibodies or antigen-binding fragments thereof (adcs), with targetable construct peptides or with other targeting molecules that are capable of delivering the p2pdox to a targeted cell, tissue or pathogen. Once delivered to the target cell, the adc or peptide conjugate is internalized, a ...
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