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Infectious Disease

Infectious Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Methods of detecting mirna
Gensignia, Inc.
May 17, 2018 - N°20180135126

Described are non-invasive methods of detecting in vivo cell death by measuring levels of ubiquitous and tissue specific mirna. The method can be applied for detection of pathologies caused or accompanied by cell death, as well as for diagnosis of infectious disease, cytotoxic effects induced by different chemical or physical factors, and the presence of specific fetal abnormalities.
NEW Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious ...
National University Of Singapore
May 17, 2018 - N°20180135016

The invention provides a chimeric receptor comprising nkg2d, dap10 and cd3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of nk cells. The invention also encompasses methods for use of nkg2d-dap10-cd3 zeta polypeptides, vectors and cells in methods for treating cancer ...
NEW Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious ...
National University Of Singapore
May 17, 2018 - N°20180135015

The invention provides a chimeric receptor comprising nkg2d, dap10 and cd3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of nk cells. The invention also encompasses methods for use of nkg2d-dap10-cd3 zeta polypeptides, vectors and cells in methods for treating cancer ...
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Infectious Disease Patent Applications
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NEW Chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious ...
National University Of Singapore
May 17, 2018 - N°20180135013

The invention provides a chimeric receptor comprising nkg2d, dap10 and cd3 zeta. Also disclosed is a composition comprising this chimeric receptor and methods for making and using it to enhance the cytotoxicity and antitumor capacity of nk cells. The invention also encompasses methods for use of nkg2d-dap10-cd3 zeta polypeptides, vectors and cells in methods for treating cancer ...
NEW Methods and intermediates for the preparation of omacetaxine and cephalotaxine derivatives thereof
Albany Molecular Research, Inc.
May 17, 2018 - N°20180134724

The present invention relates to methods and intermediates for the preparation of omacetaxine and cephalotaxine derivatives thereof. The resulting products are useful in the treatment of proliferative diseases and infectious diseases.
NEW Salts and prodrugs of 1-methyl-d-tryptophan
Newlink Genetics, Corp.
May 17, 2018 - N°20180134658

Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.
NEW Infectious Disease Patent Pack
Download 152+ patent application PDFs
Infectious Disease Patent Applications
Download 152+ Infectious Disease-related PDFs
For professional research & prior art discovery
inventor
  • 152+ full patent PDF documents of Infectious Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
NEW Cell penetrating peptides and complexes comprising the same
Amal Therapeutics Sa
May 17, 2018 - N°20180133327

The present invention provides a cell penetrating peptide derived from zebra, which is optionally linked to a cargo molecule, such as at least one antigen or antigenic epitope. The present invention also provides a complex comprising the cell penetrating peptide and the cargo molecule. In particular, compositions, such as a pharmaceutical compositions and vaccines are provided, which may be useful ...
NEW Versatile influenza virus vaccine composition
Korea Research Institute Of Bioscience And Biotechnology
May 17, 2018 - N°20180133305

The present invention relates to a versatile influenza virus vaccine composition using the ha2 helical domain of a hemagglutinin protein, which is an influenza surface protein, and to a pharmaceutical composition for preventing or treating influenza virus infectious diseases. The polypeptide expressed by seq id no: 3 and the polypeptide expressed by residues 379 to 474 of seq id no: 1 of the present ...
NEW A novel complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist
Amal Therapeutics Sa
May 17, 2018 - N°20180133295

The present invention provides a novel complex comprising a) a cell penetrating peptide, b) at least one antigen or antigenic epitope, and c) at least one tlr peptide agonist, wherein the components a)-c) are covalently linked. Moreover, the present invention also provides a nucleic acid encoding such a complex, wherein the complex is a peptide or a protein. Such ...
NEW Therapeutic ozone agent and treatment
May 17, 2018 - N°20180133248

The use of a medical therapeutic ozone agent in vivo to treat a variety of disorders including, but not limited to hypoxic conditions, autoimmune disease, fibrotic disease, inflammatory disease, neurodegenerative disease, infectious disease, lung disease, heart and vascular disease, metabolic disease, and cancer, wherein the therapeutic ozone agent is administered in a therapeutically effective amount, which can convert carbon monoxide ...
Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3)
Anaptysbio, Inc.
May 10, 2018 - N°20180127500

The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the t cell immunoglobulin and mucin protein-3 (hm-3). The invention provides a tim-3-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and ...
Antibodies directed against lymphocyte activation gene 3 (lag-3)
Anaptysbio, Inc.
May 10, 2018 - N°20180127496

The invention relates to an isolated immunoglobulin heavy chain polypeptide and an isolated immunoglobulin light chain polypeptide that bind to a protein encoded by the lymphocyte activation gene-3 (lag-3). The invention provides a lag-3-binding agent that comprises the aforementioned immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide. The invention also provides related vectors, compositions, and methods of using ...
Substituted urea depsipeptide analogs as activators of the clpp endopeptidase
St. Jude Children's Research Hospital
May 10, 2018 - N°20180127469

In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the clpp endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the ...
Infectious Disease Patent Pack
Download 152+ patent application PDFs
Infectious Disease Patent Applications
Download 152+ Infectious Disease-related PDFs
For professional research & prior art discovery
inventor
  • 152+ full patent PDF documents of Infectious Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Modified gamma delta t cells and uses thereof
Tc Biopharm Ltd
May 10, 2018 - N°20180125889

The present invention provides composition and methods for the treatment of cancer or infectious diseases in a human. The invention includes the generation and administration of gamma delta t cells that express chimeric antigen receptors (cars) comprising an antigen binding domain, a hinge domain, a transmembrane domain, a costimulatory signalling domain with the inclusion or not of a cd3 zeta ...
Use of immunesuppressant receptor
May 03, 2018 - N°20180118797

Bir1 functions as an immunosuppressive receptor, and the antagonist of bir1 has immunopotentive activity, which is able to use for preventing and/or treating a cancer, an immunodeficiency disease or an infectious disease.
Ido inhibitors
Newlink Genetics Corporation
May 03, 2018 - N°20180118753

Presently provided are ido inhibitors and pharmaceutical compositions thereof, useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (ido) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine-2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated ...
Porous silicon microparticle-based cancer vaccines and methods for potentiating anti-tumor immunity
The Methodist Hospital
May 03, 2018 - N°20180117176

Porous silicon (psi) microparticles (psm) are disclosed, which provide an important advance in the area of cancer immunotherapeutics and molecular nanomedicine. In particular, potent psm-based adjuvants are disclosed for dendritic cell-based vaccines compositions, and methods for their use in a variety of cancer immunotherapies. The psm of the present invention are also useful in developing other types of vaccines, including ...
6-amino-purin-8-one compounds
May 03, 2018 - N°20180117048

Wherein r1 is c1-6alkylamino, c1-6alkoxy, or c3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases ...
Anti-pd1 antibodies and their use as therapeutics and diagnostics
Beigene, Ltd.
April 26, 2018 - N°20180111995

Provided are antibodies that specifically bind to programmed death-1 (pd1, pdcd-1, or cd279) and inhibit pd1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by pd1-mediated functions.
Anti-tyro3 antibodies and uses thereof
Institut Curie
April 19, 2018 - N°20180105596

The present invention relates to antibodies, in particular human or humanized antibodies, that bind to the extracellular domain of human tyro3 receptor, in particular to the immunoglobulin-like domain ig-1, and reduce or inhibit the binding of human gas6 to said receptor. The invention also relates to the uses of these antibodies in the diagnosis, prevention or treatment of hyperproliferative or ...
Immune modulator for immunotherapy and vaccine formulation
Health Research, Inc.
April 19, 2018 - N°20180105562

A recombinant flagrp170 protein and pharmaceutical compositions comprising a flagrp170 protein and related molecules encoding same, and cells presenting such a protein are provided. The flagrp170 protein comprises an nf-κb-activating domain of flagellin and an atp-binding domain truncated grp170. The pharmaceutical compositions of the invention can be used for the treatment or prevention of cancer or infectious ...
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