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Indole

Indole-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Automatic dishwashing detergent composition
The Procter & Gamble Company
June 22, 2017 - N°20170175035

A neutral or acidic automatic dishwashing detergent composition including a nitrogen containing compound selected from the group consisting of imidazoles, pyrazoles, benzothiazoles, benzimidazoles, indoles, benzotriazoles, and mixtures thereof.
NEW 6h-furo[2,3-e]indole compounds for the treatment of hepatitis c
Bristol-myers Squibb Company
June 22, 2017 - N°20170174696

Compounds of formula i, including their salts, as well as compositions and methods of using the compounds are set forth. The compounds have activity against hepatitis c virus (hcv) and may be useful in treating those infected with hcv.
NEW New spiro[3h-indole-3,2'-pyrrolidin]-2(1h)-one compounds and derivatives as mdm2-p53 inhibitors
Bristol-myers Squibb Company
June 22, 2017 - N°20170174695

Wherein the groups r1 to r4, r7, a, d, e, f, v, w, x, y, n, r and q are defined in claim 1, their use as inhibitors of mdm2-p53 interaction, pharmaceutical compositions which contain compounds of this kind, their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases, and synthetic intermediates.
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NEW Substituted indoles
Vanderbilt University
June 22, 2017 - N°20170174688

Wherein r1, r2, r3, r4, r5, and r6 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions mediated and modulated by suv420h1. Also provided are pharmaceutical compositions comprised of one or more compounds of formula (i).
Antibody purification via affinity chromatography
University Of Notre Dame Du Lac
June 15, 2017 - N°20170166607

Embodiments herein provide methods of purifying monoclonal and polyclonal anti-bodies (e. G., immunoglobulins) from biological fluids, such as cell lysates, cell supernatant and ascites fluids, using small molecule affinity chromatography. Various embodiments disclose a class of small molecules that selectively bind a nucleotide binding site that is inherent to all immunoglobulins, and in various embodiments, methods are disclosed that use ...
Functionalised and substituted indoles as anti-cancer agents
Novogen Limited
June 15, 2017 - N°20170166555

The present invention relates to anti-tropomyosin compounds, processes for their preparation, and methods for treating or preventing a proliferative disease, preferably cancer, using compounds of the invention.
Indole Patent Pack
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Indole Patent Applications
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For professional research & prior art discovery
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  • 178+ full patent PDF documents of Indole-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
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Pharmaceutical composition comprising indole compound
Lg Life Sciences Ltd.
June 15, 2017 - N°20170165272

The present invention relates to a pharmaceutical composition comprising a compound of formula (1), (2) or (3) as defined in the specification for the prevention or treatment of diseases associated with oxidative stress, mitochondria dysfunction, hypoxic injury, necrosis and/or ischemic reperfusion injury, and a cosmetic composition comprising an indole compound having an antioxidant effect
Use of 7-chloro-n,n,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4h-pyridazino[4,5-b] indole-1-acetamide as a biomarker ...
Sanofi
June 08, 2017 - N°20170160287

Use of a radiolabelled form of 7-chloro-Λ/Λ,5-trimethyl-4-oxo-3-phenyl-3,5-dihydro-4/−/−pyridazino[4,5-b]indole-1-acetamide as a biomarker for the detection, in an individual, of pbr levels associated with normal and pathological conditions. Method for the detection of pbr levels associated with normal and pathological conditions. Diagnostic kit.
Novel low-molecular-compound for improving production, maintenance and proliferation of pluripotent stem cells, composition comprising the ...
Korea Research Institute Of Bioscience And Biotechnology
June 08, 2017 - N°20170159023

Provided herein are novel indoleacrylic acid-based compounds, and pharmaceutically acceptable salts thereof, useful for the production, maintenance and proliferation of pluripotent stem cells. Also provided are cell culture compositions comprising these compounds, and methods of using these compounds in the production and maintenance of pluripotent stem cells.
3-substituted 2-amino-indole derivatives
Takeda Pharmaceutical Company Limited
June 08, 2017 - N°20170158700

The present invention provides compounds of formula (i) (formula (i)) and pharmaceutically acceptable salts thereof, wherein q, x % x4, x5 x6, x7, r1, r2, r3 and r8 are as defined in the specification, processes for the preparation of such compounds, pharmaceutical compositions containing them and the use of such compounds in therapy.
Functionalised and substituted indoles as anti-cancer agents
Novogen Limited
June 08, 2017 - N°20170157135

The present invention relates to anti-tropomyosin compounds, processes for their preparation, and methods for treating or preventing a proliferative disease, preferably cancer, using compounds of the invention.
Functionalised and substituted indoles as anti-cancer agents
Novogen Ltd.
June 01, 2017 - N°20170152226

The present invention relates to anti-tropomyosin compounds, processes for their preparation, and methods for treating or preventing a disease or disorder, such as a proliferative disease (preferably cancer), using compounds of the invention.
Anti-indoleamine 2,3-dioxygenase 1 antibodies and diagnostic uses thereof
Novogen Ltd.
May 25, 2017 - N°20170146535

The invention provides antibodies that bind specifically to human indoleamine 2,3-dioxygenase 1 (ido1), and methods of using the same. The antibodies are capable of binding to a sequence comprising seq id no: 1 and specifically bind to human ido1 in formalin fixed paraffin embedded tissues. The antibodies are useful in a number of different analytical techniques, including immunohistochemistry (ihc) and immunocytochemistry (icc).
Indole Patent Pack
Download 178+ patent application PDFs
Indole Patent Applications
Download 178+ Indole-related PDFs
For professional research & prior art discovery
inventor
  • 178+ full patent PDF documents of Indole-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
(r)-pirlindole and its pharmaceutically acceptable salts for use in medicine
Novogen Ltd.
May 25, 2017 - N°20170145015

(r)-pirlindole or its pharmaceutically acceptable salts, as well as pharmaceutical compositions comprising the same for use in the therapeutic treatment and prevention of pain.
Pharmaceutically acceptable salts of pirlindole enantiomers for use in medicine
Novogen Ltd.
May 25, 2017 - N°20170143710

The present invention provides pharmaceutically acceptable salts of enantiomerically pure (r)-pirlindole and (s)-pirlindole compounds having an increased bioavailability profile for use in medicine.
(s)-pirlindole and its pharmaceutically acceptable salts for use in medicine
Novogen Ltd.
May 25, 2017 - N°20170143709

(s)-pirlindole or its pharmaceutically acceptable salts, as well as pharmaceutical compositions comprising the same for use in the therapeutic treatment and prevention of pain.
Immunoregulatory agents
Novogen Ltd.
May 25, 2017 - N°20170143649

Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
Rapid-acting insulin composition comprising a substituted citrate
Novogen Ltd.
May 18, 2017 - N°20170136097

In which: r1, r2, r3, identical or different, represent oh or aa, at least one of the r1, r2, r3 is an aa radical, aa is a radical resulting from a natural or synthetic aromatic amino acid comprising at least one phenyl group or indole group, substituted or not substituted, said aa radical having at least one free carboxylic acid ...
Complexes comprising a platinum compound and an immune checkpoint inhibitor and related methods
Massachusetts Institute Of Technology
May 11, 2017 - N°20170129911

Complexes comprising a platinum compound and an immune checkpoint inhibitor, and related methods, are generally provided. In some embodiments, the immune checkpoint inhibitor is an inhibitor for indoleamine-2,3-dioxygenase.
Compounds comprising 1,1a,2,5a-tetrahydrospiro[indole-3,2a-pyrrole]-2,5a-dione system as inhibitors p53-mdm2 protein-protein interaction
Adamed Sp. Z O.o.
May 11, 2017 - N°20170129903

A spirooxoindole compound represented by the formula selected from the group consisting of formula (ia) and (ib), wherein all symbols are as defined in the description. The compound can find use in a method of prevention and/or treatment of diseases selected from the group consisting of cancer, immune diseases, inflammatory conditions, allergic skin diseases associated with excessive proliferation, and ...
Azaindole acetic acid derivatives and their use as prostaglandin d2 receptor modulators
Adamed Sp. Z O.o.
May 11, 2017 - N°20170129884

Wherein r1 and r2 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin d2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.
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