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Immunogenic

Immunogenic-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Ror1-binding molecules, and methods of use thereof
Macrogenics, Inc.
August 17, 2017 - N°20170233472

The present invention is directed to optimized ror1-binding molecules having enhanced affinity and superior ability to mediate redirected cytotoxicity of tumor cells relative to prior ror1-binding molecules. More specifically, the invention relates to optimized ror1-binding molecules that comprise variable light chain and/or variable heavy chain (vh) domains that have been optimized for binding to an epitope ...
NEW Polyvalent pneumococcal polysaccharide-protein conjugate composition
Sk Chemical Co., Ltd.
August 17, 2017 - N°20170232101

Provided is an immunogenic composition comprising 15 different polysaccharide-protein conjugates. Each of the conjugates comprises a capsular polysaccharide prepared from different serotype streptococcus pneumoniae conjugated to a carrier protein, that is, serotypes 1, 2, 3, 4, 5, 6a, 6b, 7f, 9n, 9v, 14, 18c, 19a, 19f and 23f. An immunogenic composition formulated into a vaccine comprising an aluminum-based adjuvant increases application range with respect to pneumococcal diseases ...
NEW Functional influenza virus-like particles (vlps)
Novavax, Inc.
August 17, 2017 - N°20170232095

Recombinant influenza virus proteins, including influenza capsomers, subviral particles, virus-like particles (vlp), vlp complexes, and/or any portions of thereof, are provided as a vaccine for influenza viruses. The invention is based on the combination of two vaccine technologies: (1) intrinsically safe recombinant vaccine technology, and (2) highly immunogenic, self-assembled protein macromolecules embedded in plasma membranes and comprised of multiple copies of ...
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Immunogenic Patent Applications
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  • 328+ full patent PDF documents of Immunogenic-related inventions.
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NEW Multi-indication mrna cancer immunotherapy
Morphogenesis, Inc.
August 17, 2017 - N°20170232090

Synthetic bacterial messenger rna can be used to prepare autologous, allogenic or direct nucleic acid cancer vaccines. Cancer cells are transfected either in vitro or in vivo with mrna obtained from dna that encodes an immunogenic bacterial protein. An immune response to the cancer is generated from direct administration of the mrna in vivo or administration of vaccines prepared from ...
NEW Telomerase polypeptide vaccine for treating cancer
Ultimovacs As
August 17, 2017 - N°20170232088

A polypeptide comprising the sequence of seq. Id no. 2, 3, 4, 7 or 8. The polypeptide may have the sequence of an immunogenic fragment thereof comprising at least eight amino acids, wherein the immunogenic fragment is not one of seq. Id nos. 6 or 11 to 16. The polypeptide may have a sequence having at least 80% sequence identity to the aforementioned polypeptide or immunogenic fragment. The polypeptide ...
NEW Telomerase polypeptide vaccine for treating cancer
Ultimovacs As
August 17, 2017 - N°20170232087

A polypeptide comprising the sequence of seq. Id no. 2, 3, 4, 7 or 8. The polypeptide may have the sequence of an immunogenic fragment thereof comprising at least eight amino acids, wherein the immunogenic fragment is not one of seq. Id nos. 6 or 11 to 16. The polypeptide may have a sequence having at least 80% sequence identity to the aforementioned polypeptide or immunogenic fragment. The polypeptide ...
NEW Immunogenic Patent Pack
Download 328+ patent application PDFs
Immunogenic Patent Applications
Download 328+ Immunogenic-related PDFs
For professional research & prior art discovery
inventor
  • 328+ full patent PDF documents of Immunogenic-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
NEW Synthetic active peptide fragments
Fundaçao Oswaldo Cruz - Fiocruz
August 17, 2017 - N°20170232082

The present invention relates to peptide fragments which have one or more shared and/or similar amino acid sequences to amino acid sequences of specific portions of the 14 kda protein of s. Mansoni (sm14) or related fabps (fatty acid binding proteins), the peptide fragments functioning as continuous or discontinuous epitopic regions of the molecule or mimicking its biological activity. More ...
Formulations for small intestinal delivery
Vaxart, Inc.
August 10, 2017 - N°20170224805

Provided herein are compositions and methods for generating an immunogenic response in humans. Such compositions include an immunogenic biological agent encompassed by (ii) an agent that directs delivery of the immunogenic biological agent to the ileum of the human, wherein agent (ii) is an enteric coating (e. G., eudragit®) that has a threshold ph 5. 8-6. 8. Further provided are methods ...
Glycoconjugation processes and compositions
Pfizer Inc.
August 10, 2017 - N°20170224804

The invention provides etec linked glycoconjugates comprising a saccharide covalently conjugated to a carrier protein through a (2-((2-oxoethyl)thio)ethyl)carbamate (etec) spacer, immunogenic compositions comprising such glycoconjugates, and methods for the preparation and use of such glycoconjugates and immunogenic compositions.
Identification of immunologically protective neo-epitopes for the treatment of cancers
University Of Notre Dame Due Lac
August 10, 2017 - N°20170224799

Described herein are methods of identifying immunologically protective neo-epitopes from the cancer tissue dna of cancer patients using biophysical principles as well as bioinformatics techniques. The identification of immunologically protective neo-epitopes provides pharmaceutical compositions with a limited number of tumor-specific peptides suitable for personalized genomics-driven immunotherapy of human cancer. Specifically disclosed herein is a method of using the conformational stability ...
Malaria antigen screening method
United States Of America As Represented By The Secretary Of The Navy
August 03, 2017 - N°20170219560

The invention provides a method of identifying an antigen from a pathogen or a disease antigen comprising the use of an adenoviral vector array comprising two or more different adenoviral vectors, wherein each adenoviral vector comprises a nucleic acid sequence encoding a different antigen of a pathogen. The adenoviral vectors are administered to antigen presenting cells (apcs) in vitro or ...
Clostridium difficile immunogenic composition
Glaxosmithkline Biologicals Sa
August 03, 2017 - N°20170218031

Immunogenic compositions comprising isolated clostridium difficile cdtb proteins, including modified proteins, and fusion proteins comprising a cdta protein and a cdtb protein.
Compositions and methods for transient immune response modulation during vaccination
Duke University
August 03, 2017 - N°20170216426

In certain aspects the invention provides a selection of hiv-1 envelopes suitable for use as immunogens, and methods of using these immunogens to induce neutralizing antibodies. In certain embodiments, the immunogens are designed to trimerize. In other embodiments, the immunogenic compositions and methods comprise at least one agent for transient immune response modulation during vaccination.
Immunogenic Patent Pack
Download 328+ patent application PDFs
Immunogenic Patent Applications
Download 328+ Immunogenic-related PDFs
For professional research & prior art discovery
inventor
  • 328+ full patent PDF documents of Immunogenic-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Immunogenic lhrh composition and use thereof in pigs
United Biomedical, Inc.
August 03, 2017 - N°20170216418

A vaccine composition for castrating pigs, comprising a peptide immunogen and a veterinarily acceptable delivery vehicle or adjuvant, wherein the peptide immunogen comprises (a) a lhrh peptide of seq id no: 1, and (b) at least one t helper epitope selected from a group consisting of seq id nos: 2, 3, 4, and 5, and, optionally, an immunostimulatory peptide of seq in no: 6, wherein the ...
Pseudomonas exotoxin a with less immunogenic b cell epitopes
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv
August 03, 2017 - N°20170216398

The invention provides a pseudomonas exotoxin a (pe) comprising an amino acid sequence having a substitution of one or more of amino acid residues e420, d463, y481, l516, r563, d581, d589, and k606, wherein the amino acid residues are defined by reference to seq id no: 1. The invention further provides related chimeric molecules, as well as related nucleic acids, recombinant ...
Stabilizing alkylglycoside compositions and methods thereof
Aegis Therapeutics, Llc
August 03, 2017 - N°20170216397

The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof.
Human antibodies and proteins
Aegis Therapeutics, Llc
July 27, 2017 - N°20170210820

The present invention provides composite proteins, including antibodies, which show reduced immunogenicity. In particular, composite antibodies for use in humans are provided, in particular antibodies which have been modified to remove one or more t-cell epitopes. Methods for generating such proteins are also provided.
Monovalent anti-cd3 adjuvants
Mayo Foundation For Medical Education And Research
July 27, 2017 - N°20170209569

This document provides methods and materials related to using monovalent anti-cd3 antibodies (e. G., monovalent anti-cd3 fab fragments) as adjuvants to increase the immune response produced against an antigen (e. G., a tumor associated antigen). For example, vaccine compositions containing monovalent anti-cd3γε fab fragments in combination with tumor associated antigens (e. G., tumor associated antigens having ...
Immunogenic composition
Glaxosmithkline Biologicals S.a.
July 27, 2017 - N°20170209562

The present disclosure relates to the field of neisserial immunogenic compositions and vaccines, their manufacture and the use of such compositions in medicine. In particular the present invention relates to compositions and methods involving the factor h binding protein (fhbp) antigen. The present inventors have recognised that fhbp is poorly expressed in neisserial strains of st269 clonal complex (a subset ...
Mycoplasma hyopneumoniae vaccine
Zoetis Services Llc
July 27, 2017 - N°20170209560

This invention provides an immunogenic composition including the supernatant of a mycoplasma hyopneumoniae (m. Hyo) culture, wherein the supernatant of the m. Hyo culture has been separated from insoluble cellular material by centrifugation, filtration, or precipitation and is substantially free of both (i) igg and (ii) immunocomplexes comprised of antigen bound to immunoglobulin.
Improved factor viii preparations suitable for therapeutic use and processes to obtain these
Csl Behring Gmbh
July 27, 2017 - N°20170209546

The present invention relates to pharmaceutical preparations comprising two-chain factor viii that are essentially free of factor viii-light chains (fviii-lcs) which are not associated with factor viii-heavy chains (fviii-hcs) having higher purity and which are less immunogenic. The invention also relates to methods to test the suitability of a pharmaceutical factor viii preparation and to methods to reduce in pharmaceutical ...
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