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Immunogenic

Immunogenic-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Hla g-modified cells and methods
Escape Therapeutics, Inc.
October 12, 2017 - N°20170292952

Disclosed herein are methods for producing genetically modified cells expressing hla-g (e. G., cell surface hla-g) persistently, and nucleic acid compositions useful for generating such genetically modified cells. Also disclosed are cell therapy methods that utilize genetically modified cells that express hla-g persistently. The hla-g genetic modifications described herein provide the cells with characteristics of reduced immunogenicity and/or improved ...
Methods and compositions for intra-nasal immunization with recombinant mva encoding flagellin
Bavarian Nordic A/s
October 12, 2017 - N°20170290909

Provided herein are immunogenic compositions comprising a recombinant modified vaccinia virus ankara (mva) comprising a nucleic acid sequence encoding a flagellin, and a nucleic acid sequence encoding a heterologous disease-associated antigen, wherein the immunogenic composition induces increased t-cell and antibody mediated immune responses specific for the heterologous disease-associated antigen when administered to a subject, e. G. A human subject, and ...
Vlps containing ligands and methods related thereto
Children's Healthcare Of Atlanta, Inc.
October 12, 2017 - N°20170290906

This disclosure relates to immunogenic compositions and methods of enhancing an immune response to an antigen. In certain embodiments, the disclosure relates to virus-like carries comprising a tlr5 agonist on the exterior without an antigen.
Immunogenic Patent Pack
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Immunogenic Patent Applications
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  • 328+ full patent PDF documents of Immunogenic-related inventions.
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Multicomponent or monocomponent vaccine to be used against chagas disease, pharmaceutical compositions containing them, procedure ...
Institut National De La Santé Et De La Recherche Médicale (inserm)
October 12, 2017 - N°20170290896

A monocomponent vaccine effective to moderate the clinical consequences of chages disease, capable of stimulating an immune response against the trans-sialidase virulence factor of the trypanosoma cruzi parasite. The vaccine active ingredient is an immunogenic component with a polynucleotide encoding one or more polypeptide(s) which includes a c-terminal region composed of at least two repetitive units of amino acids, ...
Predicting allergic reactions
Alcyomics Ltd
October 05, 2017 - N°20170285001

This present invention provides a method of predicting immunogenicity and hypersensitivity or allergic reactions to chemical compounds, therapeutics, cosmetics and other chemical compositions. The method uses an in vitro assay employing autologous blood derived cells and an autologous cultured skin biopsy and is of particular utility in the identification and prediction of skin sensitizers that cause allergic contact dermatitis.
Modulation of globoseries glycosphingolipid synthesis and cancer biomarkers
Academia Sinica
October 05, 2017 - N°20170283878

The present disclosure relates to methods and compositions which can modulate the globoseries glycosphingolipid synthesis. Particularly, the present disclosure is directed to glycoenzyme inhibitor compound and compositions and methods of use thereof that can modulate the synthesis of globoseries glycosphingolipid ssea-3/ssea-4/globoh in the biosynthetic pathway; particularly, the glycoenzyme inhibitors target the alpha-4galt; beta-4galnact-i; or beta-3galt-v ...
Immunogenic Patent Pack
Download 328+ patent application PDFs
Immunogenic Patent Applications
Download 328+ Immunogenic-related PDFs
For professional research & prior art discovery
inventor
  • 328+ full patent PDF documents of Immunogenic-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Modified cells evoking reduced immunogenic responses
Zhejiang University
October 05, 2017 - N°20170283769

The present disclosure describes composition, methods, and systems associated with a genetically modified stem cell. The modified stem cell includes a reduced amount of major histocompatibility complex ii (mhc ii) as compared to a corresponding wild-type cell. Further, the modified cell has decreased immunogenicity as compared to the corresponding wild-type cell.
Compositions and methods for enhanced innate immunity
Colorado State University Research Foundation
October 05, 2017 - N°20170281754

The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes; a mixture of toll like receptor 3 (tlr3) and toll like receptor 9 (tlr9) ligands; and a cellular adhesion agent, and methods of using such compositions. In certain aspects, disclosed compositions are administered to a mammal to induce a non-specific innate immune response at mucosal ...
Antigen delivery system
Sri International
October 05, 2017 - N°20170281752

A minimal antigen delivery system consists essentially of pegylated stealth liposomes loaded with an immunogenic human leukocyte antigen (hla) class restricted peptide and surface modified with a cell targeting peptide which mediates binding and internalization of the liposomes into a target cell.
Peptide sequences and compositions
Peptcell, Ltd.
October 05, 2017 - N°20170281750

The present specification discloses an immunogenic composition comprising polypeptide, wherein each of the polypeptides has no more than 100 amino acids, which polypeptides comprises one or more sequences having at least 60% homology with any of seq id 1-4, or comprises two or more epitopes having 7 amino acids or more, each epitope having at least 60% homology with a sub-sequence of any of ...
Method of treatment
Glaxosmithkline Biologicals Sa
October 05, 2017 - N°20170281744

The application discloses a method of immunising against staphylococcus aureus infection comprising a step of administering to a human patient a single dose of an immunogenic composition comprising; (i) a staphylococcus aureus clfa protein or immunogenic fragment thereof at a dose of 5-50, 10-30, 5-15 or 20-40 μg and (ii) a pharmaceutically acceptable excipient; wherein the ph of ...
Serodiagnosis of salmon poisoning disease
Ohio State Innovation Foundation
October 05, 2017 - N°20170281740

Neorickettsia helminthoeca is an obligate intra-cytoplasmic bacterium that causes salmon poisoning disease (spd), an acute, febrile, fatal disease of dogs. Disclosed are compositions and methods for the immunodetection of n. Helminthoeca in a canine subject. Also disclosed are immunogenic n. Helminthoeca peptides that can be used in a vaccine for n. Helminthoeca.
Modified forms of pseudomonas exotoxin a
Intrexon Corporation
September 28, 2017 - N°20170275600

Pseudomonas exotoxin a or “pe” is a 66 kd, highly potent, cytotoxic protein secreted by the bacterium pseudomonas aeruginosa. Various forms of pe have been coupled to other proteins, such as antibodies, to generate therapeutically useful cytotoxin conjugates that selectively target cells of a desired phenotype (such as tumor cells). In the present invention, peptides spanning the ...
Immunogenic Patent Pack
Download 328+ patent application PDFs
Immunogenic Patent Applications
Download 328+ Immunogenic-related PDFs
For professional research & prior art discovery
inventor
  • 328+ full patent PDF documents of Immunogenic-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
Aura Biosciences, Inc.
September 28, 2017 - N°20170274099

The invention relates to methods for producing papilloma-derived nanosphere particles that contain therapeutic, diagnostic, or other agents. The invention also provides nanosphere particle preparations that are useful for selectively delivering therapeutic, diagnostic, and/or other agents to cancer cells of subjects without eliciting a serotype-specific immunogenic response in the subjects.
Immunological reagent
The University Of Melbourne
September 28, 2017 - N°20170274068

The present invention provides an immunogenic composition comprising a charged antigen electrostatically associated with a toll-like receptor (tlr) targeting moiety. The tlr targeting moiety comprises a tlr-2 agonist covalently attached to polyethylene glycol and to a hyper-branched charged peptide.
Thermostable, chromatographically purified nano-vlp vaccine
The Government Of The United States As Represented By The Secretary Of The Army
September 28, 2017 - N°20170274063

In this application is described a method for preparing nano-vlp composition, thereby permitting purification using chromatography and filtration. The nano-vlp composition has a more uniform size range of filovirus particles, roughly 230 nm diameter, allowing ease of manipulation of the composition, while retaining gp conformational integrity and the antigenic effectiveness of the vaccine. Additionally, the nano-vlp can be lyophilized without loss ...
Complex of immunogenic polyproteins of m. hyopneumoniae, synthetic gene encoding the complex of immunogenic polyproteins ...
Ouro Fino Saude Animal Ltda
September 28, 2017 - N°20170274062

The present invention relates to a complex of polyproteins containing immunogenic regions derived from the p36, p46, hsp, nrdf, p97, mhp271 e p216 antigens of m. Hyopneumoniae, which regions are fused with segments of the rrp4. Rrp41 and rrp42 carrier proteins of p. Abyssi, forming a single complex. The present invention further provide the following objects: (i) a gene coding ...
Vaccines against genital herpes simplex infections
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College
September 21, 2017 - N°20170266275

The present invention provides vaccines for treating or preventing a herpes simplex virus infection and methods of using and making the vaccine. Further provided are recombinant herpes simplex virus genomes, recombinant viruses, and immunogenic compositions.
Transgenic vero-cd4/ccr5 cell line
International Aids Vaccine Initiative
September 21, 2017 - N°20170266272

The present relation relates to a transgenic vero cell line expressing cd4 and ccr5. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
Il-9 secreting cd8+ tc9 cells and method of treating cancer
The Cleveland Clinic Foundation
September 21, 2017 - N°20170266233

A method of producing a population of cd8+ tc9 lymphocytes is provided including priming a population of naïve cd8+ t cells by contacting the population of naïve cd8+ t cells with an immunogenic peptide, in the presence of a tc9 supportive environment, thereby producing a population of cd8+ tc9 lymphocytes which secrete il-9. Purified populations of ...
Modulation of tissue transglutaminase activation in disease
The Board Of Trustees Of The Leland Stanford Junior University
September 21, 2017 - N°20170266198

Compositions and methods are provided for modulating the physiological activation of tissue transglutaminase (tg2); which methods can include inhibiting the activation of tg2 associated with enteric inflammatory disorders, which disorders may include celiac disease, irritable bowel syndrome, crohn's disease, dermatitis herpetiformis, and the like. In other embodiments of the invention, methods are provided for reducing undesirable paracellular transport in enteric ...
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