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Immune Response

Immune Response-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Compositions and methods for modulating an immune response
Board Of Trustee Of Michigan State University
October 12, 2017 - N°20170292127

The disclosure relates to, among other things, agents that modulate the homophilic interaction between two cracc polypeptides, methods for making such agents, and therapeutic applications in which the agents are useful. For example, the agents described herein are useful for modulating an immune response in a mammal. Also featured are screening methods for identifying additional agents capable of modulating the ...
Pichinde virus reverse genetics systems and methods of use
Regents Of The University Of Minnesota
October 12, 2017 - N°20170292119

Provided herein are genetically engineered pichinde viruses that include three ambisense genomic segments. The first genomic segment includes a coding region encoding a z protein and a coding region encoding a l rdrp protein. The second genomic segment includes a coding region encoding a nucleoprotein (np) and the third genomic segment includes a coding region encoding a glycoprotein. Each of ...
Modulation of stimulatory and non-stimulatory myeloid cells
The Regents Of The University Of California
October 12, 2017 - N°20170291946

Provided herein are methods and compositions for enhancing an immune response and/or for the treatment of an immune-related condition in an individual, e. G., cancer, comprising killing, disabling, or depleting non-stimulatory myeloid cells using an antigen binding protein such as an antibody or antigen binding fragment thereof.
Immune Response Patent Pack
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Immune Response Patent Applications
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  • 464+ full patent PDF documents of Immune Response-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Vlps containing ligands and methods related thereto
Children's Healthcare Of Atlanta, Inc.
October 12, 2017 - N°20170290906

This disclosure relates to immunogenic compositions and methods of enhancing an immune response to an antigen. In certain embodiments, the disclosure relates to virus-like carries comprising a tlr5 agonist on the exterior without an antigen.
Means and methods for active cellular immunotherapy of cancer by using tumor cells killed by ...
Sotio A.s.
October 12, 2017 - N°20170290899

Disclosed are pharmaceutical compositions for inducing an immune response against tumor cells comprising tumor cells which are made apoptotic by treatment with high hydrostatic pressure and dendritic cells, and methods for producing such compositions.
Priming of an immune response
University Of Copenhagen
October 12, 2017 - N°20170290898

The present invention relates to a technology and method of priming of an immune response using invariant chain linked antigen, when these are used to prime a subsequent booster immunization using any suitable vacci.
Immune Response Patent Pack
Download 464+ patent application PDFs
Immune Response Patent Applications
Download 464+ Immune Response-related PDFs
For professional research & prior art discovery
inventor
  • 464+ full patent PDF documents of Immune Response-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Multicomponent or monocomponent vaccine to be used against chagas disease, pharmaceutical compositions containing them, procedure ...
Immatics Biotechnologies Gmbh
October 12, 2017 - N°20170290896

A monocomponent vaccine effective to moderate the clinical consequences of chages disease, capable of stimulating an immune response against the trans-sialidase virulence factor of the trypanosoma cruzi parasite. The vaccine active ingredient is an immunogenic component with a polynucleotide encoding one or more polypeptide(s) which includes a c-terminal region composed of at least two repetitive units of amino acids, ...
Heartworm vaccine, methods and uses thereof
Merial Inc.
October 12, 2017 - N°20170290895

The present invention encompasses a vaccine composition and method of use for treating heartworm infestation in mammals. The vaccine composition includes chimeric antigens engineered and manufactured using the genetic code (i. E., the amino acid or protein sequence) of the target sequence. After introduction of the vaccine composition containing the target antigen into the host (e. G., a canine), the ...
Compositions and methods for treating and preventing inflammation
Rsem, Limited Partnership
October 05, 2017 - N°20170283502

The present invention provides novel compounds compositions and methods for (i) treating or preventing inflammation; and (ii) preventing or reducing hyperactivation of innate immune response, by inhibiting nrp1-dependent cell-signaling. Also provided are compounds, composition, and methods of specifically inhibiting sema3a-mediated cell signaling.
Cancer vaccine compositions and methods of use thereof
University Of Washington
October 05, 2017 - N°20170283475

The present application describes compositions that include an epitope of a peptide that elicits an immune response in a subject following administration. The compositions described herein include nucleic acids. The present application also describes compositions that include peptides. Also described herein are methods that include administering a composition comprising an epitope of a peptide to a subject in need thereof.
Immune system modulation for prophylaxis and treatment of diseases and disorders
Marpe Holdings, Llc
October 05, 2017 - N°20170283460

The invention is directed to biological response modifiers (brm) which may contain one or more compounds, and to methods for enhancement of an immune system with brms of the invention including augmenting a specific immune response either prophylactically or for treatment, as an adjuvant or vaccine when coupled with a pathogenic antigen, and for boosting an immune system generally. The ...
Combination therapy for inducing immune response to disease
Ibc Pharmaceuticals, Inc.
October 05, 2017 - N°20170281767

The present invention concerns compositions and methods of use of bispecific antibodies comprising at least one binding site for trop-2 (egp-1) and at least one binding site for cd3. The bispecific antibodies are of use for inducing an immune response against a trop-2 expressing tumor, such as carcinoma of the esophagus, pancreas, lung, stomach, colon, rectum, urinary bladder, breast, ovary, ...
Compositions and methods for enhanced innate immunity
Colorado State University Research Foundation
October 05, 2017 - N°20170281754

The disclosed compositions and methods relate to an immunogenic composition that, in certain aspects, comprise cationic liposomes; a mixture of toll like receptor 3 (tlr3) and toll like receptor 9 (tlr9) ligands; and a cellular adhesion agent, and methods of using such compositions. In certain aspects, disclosed compositions are administered to a mammal to induce a non-specific innate immune response at mucosal ...
Immune Response Patent Pack
Download 464+ patent application PDFs
Immune Response Patent Applications
Download 464+ Immune Response-related PDFs
For professional research & prior art discovery
inventor
  • 464+ full patent PDF documents of Immune Response-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
H3.3 ctl peptides and uses thereof
Regents Of The University Of California
October 05, 2017 - N°20170281742

Peptides that generate an immune response to glioma-related h3. 3 proteins and methods of their use are provided.
Method of treatment using liposomally formulated reduced glutathione to cooperate with il-10 to modulate inflammatory ...
Western University Of Health Sciences
October 05, 2017 - N°20170281714

In the setting of chronic infection with a pathogen, the immune system must adapt to the ongoing presence of inflammatory responses driven by the pathogen in order to control the replication of the infecting agent at an acceptable level while limiting immune-mediated damage (immunopathology) (1). A complex interaction is required to accomplish this using a balance of immune related cytokines to ...
Immunomodulation using spores and pollen grains
Texas Tech University System
October 05, 2017 - N°20170281545

The present invention includes compositions, methods of making and using the compositions for modulating the immune response in a subject by providing a vaccine composition having a pollen or spore disposed in a pharmaceutical carrier for delivery to a subject, wherein the pollen or spore comprises multiple pores that connect an outer surface of the pollen/spore to an inner ...
Antibodies and molecules derived therefrom that bind to steap-1 proteins
Agensys, Inc.
September 28, 2017 - N°20170275377

Antibodies and molecules derived therefrom that bind to novel steap-1 protein, and variants thereof, are described wherein steap-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in table i. Consequently, steap-1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The steap-1 gene or fragment thereof, or its encoded protein, ...
Combination therapy with t-cell redirecting bispecific antibodies and checkpoint inhibitors
Ibc Pharmaceuticals, Inc.
September 28, 2017 - N°20170275375

The present invention concerns compositions and methods of use of bispecific antibodies comprising at least one binding site for a tumor-associated antigen (taa) and at least one binding site for an antigen expressed on an effector t cell, nk cell, monocyte or neutrophil. The bispecific antibodies are of use for inducing an immune response against a taa-expressing tumor. The methods ...
Herpes simplex virus vaccine
Genvec, Inc.
September 28, 2017 - N°20170275339

Herpes simplex virus (hsv) antigens that elicit an hsv-specific immune response and can be used to treat or prevent hsv infection are provided. Nucleic acid sequences, polypeptides, vectors, and compositions, as well as methods to induce an immune response against hsv, treat or prevent hsv disease, induce a t cell response against hsv, and induce an antibody response against hsv ...
Cytotoxic t lymphocyte inducing immunogens for prevention treatment and diagnosis of dengue virus infection
Emergex Vaccines Holdings Limited
September 28, 2017 - N°20170275338

Dengue fever (df) and dengue hemorrhagic fever (dhr) are significant global public health problems and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Live attenuated and subunit vaccine candidates, which are under clinical evaluation, induce primarily an antibody response to the virus and minimal cross-reactive t cell responses. ...
Compositions and methods for the prevention and treatment of cancer
Uti Limited Partnership
September 28, 2017 - N°20170274096

Conventional cancer immunotherapy falls short at efficiently expanding t cells that specifically target cancerous cells in numbers sufficient to significantly reduce the tumor size or cancerous cell number in vivo. To overcome this limitation, provided herein are nanoparticles coated with mhc class i and/or class ii molecules presenting tumor-specific antigens and co-stimulatory molecules and their use to expand antigen-specific ...
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