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Immune Disorder

Immune Disorder-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Lgr5+ somatic stem cells
Stembios Technologies, Inc.
May 17, 2018 - N°20180135009

A method for treating a condition, comprising administering to a subject in need thereof a composition that contains somatic stem cells that are 2 to less than 6 micrometers in size and lgr5+, wherein the condition is selected from the group consisting of neurodegenerative disorder, muscle-degenerative disease, cancer, metabolic disorder, autoimmune disorder, inflammatory disorder, heart disorder, circulatory disorder, a condition associated with ...
Antigen-binding proteins that antagonize leptin receptor
Regeneron Pharmaceuticals, Inc.
May 10, 2018 - N°20180127508

The present invention provides antibodies and antigen-binding fragments of antibodies that bind to leptin receptor (lepr), and methods of using the same. According to certain embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that bind lepr and antagonize lepr signaling. In certain embodiments, the invention includes antibodies and antigen-binding fragments of antibodies that bind lepr in the presence ...
Induced expression of brain derived neurotrophic factor (bdnf) for treatment of neuromuscular, neurodegenerative, autoimmune, developmental ...
Mitochon Pharmaceuticals, Inc.
May 10, 2018 - N°20180125794

A method of treating a host of neuromuscular, neurodegenerative, developmental, autoimmune and metabolic diseases/disorders related to aging, such as traumatic injury, stroke, huntington's disease, epilepsy, multiple sclerosis (ms), lupus, type-1 and type-2 diabetes, maturity onset diabetes of the young (mody), myasthenia gravis (mg), rheumatoid arthritis (ra), graves' disease, guillain-barré syndrome (gb s), metabolic syndrome, muscular dystrophy or duchenne ...
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Immune Disorder Patent Applications
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  • 119+ full patent PDF documents of Immune Disorder-related inventions.
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Deuterium-enriched isoindolinonyl-piperidinonyl conjugates and oxoquinazolin-3(4h)-yl-piperidinonyl conjugates and methods of treating medical disorders using ...
Deuterx, Llc
May 03, 2018 - N°20180118758

The invention provides deuterium-enriched isoindolinonyl-piperidinonyl conjugates, deuterium-enriched oxoquinazolin-3(4h)-yl-piperidinonyl conjugates, pharmaceutical compositions, and methods of using such conjugates and pharmaceutical compositions to treat cancer, angiogenesis disorders, immune disorders, and other medical disorders.
New compounds i
May 03, 2018 - N°20180118744

And their pharmaceutically acceptable salts, solvates, hydrates, geometrical isomers, tautomers, optical isomers or n-oxides, which are inhibitors of ssao activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment of medical conditions wherein inhibition of ssao activity is beneficial, such as inflammatory diseases and immune disorders.
Novel aryl-cyanoguanidine compounds
Bayer Pharma Aktiengesellschaft
May 03, 2018 - N°20180118722

The present invention relates to protein-lysine n-methyltransferase smyd2 (set and mynd domain-containing protein 2) inhibitors, in particular smyd2-inhibitory substituted cyanoguanidine-pyrazolines of general formula (i), wherein r1, r3, r4, r5 and n have the meaning as described and defined herein, as well as to pharmaceutical compositions comprising compounds according to the invention and to their prophylactic and therapeutic use for hyperproliferative ...
Immune Disorder Patent Pack
Download 119+ patent application PDFs
Immune Disorder Patent Applications
Download 119+ Immune Disorder-related PDFs
For professional research & prior art discovery
inventor
  • 119+ full patent PDF documents of Immune Disorder-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Shmt inhibitors
The Trustees Of Princeton University
May 03, 2018 - N°20180117010

The present invention relates to a method for the treatment of cancer or an autoimmune disorder, comprising the administration of a serine hydroxymethyltransferase (shmt) inhibitor, and in particular the administration of pyrazolopyran compounds of formula (vi) as presently described, wherein the compounds are capable of inhibiting a mammalian shmt, such as human shmt1 and/or shmt2. The treatment method further ...
Autoimmune disorder treatment using rxr agonists
Trustees Of Dartmouth College
May 03, 2018 - N°20180116985

The present specification provides rxr agonist compounds, compositions comprising such rxr agonists, and methods using such compounds and compositions to treat an autoimmune disorder, inflammation associated with an autoimmune disorder and/or a transplant rejection as well as use of such rxr agonists to manufacture a medicament and use of such compounds and compositions to treat an autoimmune disorder, inflammation ...
Antigenic decoy entrapment filtration device and treatment methods for autoimmune disorders
Henley Development Corp.
April 26, 2018 - N°20180110912

A method for filtering blood is disclosed that in one embodiment includes the steps of depositing unfiltered blood along at least one side of a semi-permeable surface having multiple pores, depositing target tissue along at least an opposing side of the semi-permeable surface, and permitting the unfiltered blood to flow at least partially along the semi-permeable surface to filter the ...
Benzimidazole derivates useful as inhibitors of mammalian histone deacetylase activity
Kancera Ab
April 26, 2018 - N°20180110755

A compound of formula (i) or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the compound. The compound is useful in therapy, for the treatment of disorders mediated by hdac6, such as autoimmune disorders, neurodegenerative disorders and hyperproliferative disorders, such as cancer.
Boronic acid derivatives
Merck Patent Gmbh
April 19, 2018 - N°20180105539

Compounds of formula (i) are inhibitors of lmp7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.
Boronic acid derivatives
Merck Patent Gmbh
April 19, 2018 - N°20180105538

Compounds of formula (i) are inhibitors of lmp7 and can be employed, inter alia, for the treatment of an autoimmune disorder or hematological malignancies.
Method of treating skin disorders
Mymd Pharmaceuticals, Inc.
April 19, 2018 - N°20180104229

In one aspect, a method of treating a disorder associated with chronic inflammation includes administering to an individual in need thereof a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof. In some aspects, the disorder is a cancer, an autoimmune disorder, hypertension, or autism. In other aspects, isomyosmine is administered to treat viral infections or disorders associated ...
Immune Disorder Patent Pack
Download 119+ patent application PDFs
Immune Disorder Patent Applications
Download 119+ Immune Disorder-related PDFs
For professional research & prior art discovery
inventor
  • 119+ full patent PDF documents of Immune Disorder-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Controlled release pharmaceutical compositions comprising a fumaric acid ester
Fwp Ip Aps
April 12, 2018 - N°20180098957

The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e. G. Psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designated to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance ...
Indazolyl thiadiazolamines and related compounds for inhibition of rho-associated protein kinase and the treatment of ...
Lycera Corporation
April 05, 2018 - N°20180093978

The invention provides indazolyl thiadiazolamines and related compounds, pharmaceutical compositions, methods of inhibiting rho-associated protein kinase, and methods of treating inflammatory disorders, immune disorders, fibrotic disorders, and other medical disorders using such compounds. An exemplary indazolyl thiadiazolamine compound is an n-(5-[5-[(1h4ndazol-5-yl)amino]-1,3,4-thiadiazol-2-yl]pyridin-3-yl)acetamide compound.
Targeted apheresis using binding agents or ligands immobilized on membranes
April 05, 2018 - N°20180093032

This invention teaches a method of targeted apheresis that can be used to treat a variety of different diseases including infectious diseases, autoimmune disorders, and reducing circulating biomarkers associated with certain disorders e. G. Pre-eclampsia. This invention discloses the use of apheresis membranes as the support matrix upon which one or more different binding agents (e. G. Antibodies, aptamers, binding ...
Methods of treating immune disorders using pd-1 binding proteins
Celgene Corporation
April 05, 2018 - N°20180092975

Provided herein are methods for managing, treating, or preventing immune disorders, such as autoimmune diseases, using proteins that specifically bind to programmed death-1 (pd-1) and modulate the expression and/or activity of pd-1.
Pharmaceutical composition containing dimethyl fumarate for administration at a low daily dose
Fwp Ip Aps
April 05, 2018 - N°20180092875

The present invention relates to pharmaceutical compositions containing dimethyl fumarate (dmf), more specifically, the present invention relates to a pharmaceutical composition for oral use in treating hyperproliferative, inflammatory or autoimmune disorders by administering a low daily dosage in the range of 410 mg±5% or 400 mg±5% dimethyl fumarate, wherein the pharmaceutical formulation is in the form of an erosion matrix ...
Substituted n-(lh-indazol-4-yl)imidazo[l,2-a]pyridine-3-carboxamide compounds as type iii receptor tyrosine ...
March 29, 2018 - N°20180086758

And pharmaceutically acceptable salts thereof in which r1, r2, r3, r4, r5 and r6 have the meanings given in the specification, are inhibitors of cfms and are useful in the treatment of fibrosis, bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases, pain and burns in a mammal.
Methods and compositions for modulating the immune system with arginase i
Bio-cancer Treatment International Limited
March 29, 2018 - N°20180085440

Methods and compositions comprising recombinant arginase i proteins which are capable of depleting the plasma arginine levels in a subject are disclosed. The methods and compositions can be used to modulate the activity of the immune system in a subject. Modulation of the immune system is useful in the treatment of immune disorders and in preventing rejection of a transplanted ...
Eluting matrix and uses thereof
The General Hospital Corporation
March 15, 2018 - N°20180075706

Cxcl12 polypeptide eluting matrices encapsulating at least one cell are described for use in the treatment of autoimmune disorders.
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