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Immune Diseases

Immune Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Aptamers for use against autoantibody-associated diseases
Berlin Cures Holding Ag
August 10, 2017 - N°20170226513

The present invention relates to new aptamer molecules for use in the treatment and/or diagnosis of autoimmune diseases associated with autoantibodies against g-protein coupled receptors, a pharmaceutical composition comprising such aptamer molecules, an apheresis column comprising such aptamer molecules and a method for the determination of nucleotide sequences for use as sequences of aptamer molecules.
Antibody therapeutics that bind cd137
Sorrento Therapeutics, Inc.
August 10, 2017 - N°20170226215

There is disclosed compositions and methods relating to or derived from anti-cd137 antibodies. More specifically, there is disclosed fully human antibodies that bind cd137, cd137-antibody binding fragments and derivatives of such antibodies, and cd137-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, ...
An anti-cd45rc antibody for use as drug
UniversitÉ De Nantes
August 10, 2017 - N°20170226209

The invention relates to an isolated anti-cd45rc antibody for use in preventing or treating transplant rejection, autoimmune diseases, unwanted immune responses against proteins expressed in the course of gene therapy and/or therapeutic proteins, allergy as well as lymphoma or cancer which are associated with cd45rc+ cells. The invention relates to an isolated anti-cd45rc antibody for use ...
Immune Diseases Patent Pack
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Immune Diseases Patent Applications
Download 177+ Immune Diseases-related PDFs
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inventor
  • 177+ full patent PDF documents of Immune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Crystalline forms of a bruton's tyrosine kinase inhibitor
Pharmacyclics Llc
August 10, 2017 - N°20170226112

Described herein is the bruton's tyrosine kinase (btk) inhibitor 1-((r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the btk inhibitor, as well as methods of using the btk inhibitor, alone or in combination with other ...
Methods of treating inflammatory and autoimmune diseases and disorders
Yale University
August 10, 2017 - N°20170224617

Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid ...
Her2/neu-specific antibodies and methods of using same
Macrogenics, Inc.
August 03, 2017 - N°20170218083

This invention relates to antibodies that specifically bind her2/neu, and particularly chimeric 4d5 antibodies to her2/neu, which have reduced glycosylation as compared to known 4d5 antibodies. The invention also relates to methods of using the 4d5 antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious ...
Immune Diseases Patent Pack
Download 177+ patent application PDFs
Immune Diseases Patent Applications
Download 177+ Immune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Immune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Immunoglobulin constant region fc receptor binding agents
Gliknik Inc.
August 03, 2017 - N°20170218049

Ivig replacement compounds are derived from recombinant and/or biochemical creation of immunologically active biomimetic(s). These replacement compounds are then screened in vitro to assess each replacement compound's efficiency at modulating immune function. Particular replacement compounds are selected for further in vivo validation and dosage/administration optimization. Finally, the replacement compounds are used to treat a wide range of ...
Population of immunoregulatory t cells specific for an irrelevant antigen and uses thereof for preventing ...
Universite Paris Est Creteil Val De Marne
August 03, 2017 - N°20170216417

The present invention relates methods and compositions for preventing or treating various immune diseases including graft-versus-host disease (gvhd) using populations or compositions of immunoregulatory t cells specific for an irrelevant antigen; such cells being activated in vivo by a simultaneous, separate or sequential administration of said antigen.
Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
School Corporation, Azabu Veterinary Medicine Educational Institution
August 03, 2017 - N°20170216378

Species of human-derived bacteria belonging to the clostridia class have been shown to induce accumulation of regulatory t cells (treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them
School Corporation, Azabu Veterinary Medicine Educational Institution
August 03, 2017 - N°20170216293

Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
Automated immunoanalyzer system for performing diagnostic assays for allergies and autoimmune diseases
Hycor Biomedical, Llc
July 27, 2017 - N°20170212111

A quantitative method for performing an automated diagnostic assay, comprising: incubating a capture reagent with a streptavidin-coated medium to form a solid phase complex; washing the solid phase complex to remove excess capture reagent; incubating the solid phase complex with a serum sample to form an immune complex; washing the immune complex to remove any unbound sample; incubating the immune ...
Use of pdl1 expressing cells to convert t cells into regulatory t cells
The United States Of America, As Represented By The Secretary, Department Of Health And Human
July 27, 2017 - N°20170211042

The present invention provides methods and compositions for converting a t cell into a cell that exhibits at least one regulatory t cell phenotype. The converted t cell is generated by contacting a t cell with a cell that is modified to comprise an agent capable of activating pd1 signaling in a t cell. The converted t cell is useful ...
Antibody binding to fcrn for treating autoimmune diseases
Hanall Biopharma Co., Ltd.
July 27, 2017 - N°20170210805

The present disclosure relates to an isolated anti-fcrn antibody, which is an antibody binding to fcrn (stands for neonatal fc receptor, also called fcrp, fcrb or brambell receptor) that is a receptor with a high affinity for igg or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method ...
Immune Diseases Patent Pack
Download 177+ patent application PDFs
Immune Diseases Patent Applications
Download 177+ Immune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Immune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Composition containing smad protein for treatment of autoimmune diseases, a fusion protein comprising smad protein, ...
Hanall Biopharma Co., Ltd.
July 27, 2017 - N°20170210783

The present invention relates to a composition and a fusion protein for prevention or treatment of autoimmune diseases, which contain a smad protein, and provides a method for prevention or treatment of autoimmune diseases, including lupus nephritis and rheumatoid arthritis.
Pegylated interferon-beta variant
Abion Inc.
July 27, 2017 - N°20170209588

The present invention provides a pegylated ifn-β variant and a composition for preventing or treating hyperproliferative diseases, inflammatory diseases, autoimmune diseases or viral infectious diseases, the composition comprising the pegylated ifn-β variant as an effective ingredient. The pegylated ifn-β variant of the present invention has an excellent anti-viral efficacy, immune regulatory function and anti-cell ...
Method for preparing dendritic cells with increased specific gene expression, and composition for treating or ...
Jw Creagene Inc.
July 27, 2017 - N°20170209557

The present invention relates to a method for generating semi-mature dendritic cells by treating immature dendritic cells with the auto-antigen, cytokine, and pge2 as a target for the treatment of autoimmune diseases, particularly rheumatoid arthritis, in which the levels of nr4a2 and/or ubash3b at gene or protein are increased more than 2-fold compared to the immature dendritic ...
Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
School Corporation, Azabu Veterinary Medicine Educational Institution
July 27, 2017 - N°20170209502

Species of human-derived bacteria belonging to the clostridia class have been shown to induce accumulation of regulatory t cells (treg cells) in the colon and suppress immune functions. Pharmaceutical compositions containing these bacteria can be used to prevent and treat immune-mediated diseases such as autoimmune diseases.
Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
Delinia, Inc.
July 20, 2017 - N°20170204154

This invention provides for a fusion protein between an il2αβγ selective agonist protein (il2 selective agonist) and a igg fc protein using a linker. The il2 selective agonist moiety provides a therapeutic activity by selectively activating the il2αβγ form of the receptor, thus selectively stimulating tregs. The fc ...
Method of designing a peptide and/or peptide derivative for modulating gamma-c-cytokine activity
Bioniz, Llc
July 20, 2017 - N°20170204153

The γc-family cytokines, interleukin-2 (il-2), interleukin-4 (il-4), interleukin-7 (il-7), interleukin-9 (il-9), interleukin-15 (il-15), and interleukin-21 (il-21), are associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (gvhd). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools. ...
An isolated interleukin-34 polypeptide for use in preventing transplant rejection and treating autoimmune diseases
UniversitÉ De Nantes
July 20, 2017 - N°20170202921

The invention relates to an isolated interleukin-34 (il-34) polypeptide for use in preventing or treating graft rejection, autoimmune disease, unwanted immune response against therapeutic proteins and allergy. The invention also provides an in vitro method for determining whether a patient is at risk of transplant rejection, autoimmune diseases, unwanted immune response against therapeutic proteins or allergies, comprising a step of ...
Pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them
UniversitÉ De Nantes
July 20, 2017 - N°20170202851

Wherein a1, a2, ra, rb, rc, rd, r3, r4, r5 and t are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
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