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Immune Diseases

Immune Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Immune cell trapping devices and methods for making and using the same
President And Fellows Of Harvard College
June 14, 2018 - N°20180164298

Embodiments herein described provide devices for identifying and collecting rare cells or cells which occur at low frequency in the body of a subject, such as, antigen-specific cells or disease-specific cells. More specifically, the devices are useful for trapping immune cells and the devices contain a physiologically-compatible porous polymer scaffold, a plurality of antigens, and an immune cell-recruiting agent, wherein ...
Chimeric antigen receptors (cars), compositions and methods thereof
Icell Gene Therapeutics Llc
June 14, 2018 - N°20180162939

The present disclosure provides chimeric antigen receptors, compostions, and methods thereof. In one embodiment the present disclosure provides a method of treating autoimmune diseases, asthma, and preventing or mediating organ rejection in a subject..
Inhibitors of leukotriene a4 hydrolase
Celtaxsys, Inc.
June 14, 2018 - N°20180162854

The present invention is directed to compounds encompassed by the formula (i), pharmaceutical compositions thereof, methods for inhibiting lta-4 hydrolase, and methods for the treatment of a disease and disorder which is ameliorated by the inhibition of lta4-h activity. Non-limiting examples of such diseases and conditions include inflammatory and autoimmune diseases and disorders..
Immune Diseases Patent Pack
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Immune Diseases Patent Applications
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  • 177+ full patent PDF documents of Immune Diseases-related inventions.
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Substituted anilines as ccr(4) antagonists
Chemocentryx, Inc.
June 14, 2018 - N°20180162846

Aniline compounds are provided which bind to ccr(4) and are useful for the treatment of diseases such as allergic diseases, autoimmune diseases, graft rejection and cancer.. .
Treatment of autoimmune diseases with deep brain stimulation
Aleva Neurotherapeutics
June 14, 2018 - N°20180161574

Techniques using electrical stimulation for treating an autoimmune disease by means of an implantable pulse generator and at least one electrode. An electrode lead is surgically implanted in a region of the insular cortex to deliver electrical stimulation.
Methods to treat diseases with protein, peptide, antigen modification and hemopurification
June 14, 2018 - N°20180161410

The current invention discloses methods to modify protein and peptide and antigen to treat disease such as pathogen infection, autoimmune diseases and cancer. The method involves increasing the molecular weight of the protein by connecting multiple peptide units with site specific conjugation to extend the in vivo half life.
Immune Diseases Patent Pack
Download 177+ patent application PDFs
Immune Diseases Patent Applications
Download 177+ Immune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Immune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Estriol therapy for treatment of multiple sclerosis
The Regents Of The University Of California
June 14, 2018 - N°20180161346

The present invention discloses administering steroid hormones to mammals to treat autoimmune related diseases, including post-partum auto immune diseases. Most preferably the invention uses estrogens, estranges, estriol or estrogen receptor active agents to prevent or ameliorate clinical symptoms of these th1-mediated (cell-mediated) autoimmune diseases known to either have an initial onset following the birth of a child or which ...
Crystalline forms of a bruton's tyrosine kinase inhibitor
Pharmacyclics Llc
June 07, 2018 - N°20180155352

Described herein is the bruton's tyrosine kinase (btk) inhibitor 1-((r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the btk inhibitor, as well as methods of using the btk inhibitor, alone or in combination with other ...
Pyrrolopyrimidine compounds and their uses
Astex Therapeutics Ltd.
June 07, 2018 - N°20180155351

The disclosed compounds relate to treatments and therapies for protein kinase-associated disorders. There is also a need for compounds useful in the treatment or prevention or amelioration of one or more symptoms of cancer, transplant rejections, and autoimmune diseases.
Aberrant cell-restricted immunoglobulins provided with a toxic moiety
Apo-t B.v.
June 07, 2018 - N°20180154013

Described are immunoglobulins provided with a toxic moiety, comprising at least an immunoglobulin variable region that specifically binds to an mhc-peptide complex preferentially associated with aberrant cells. These immunoglobulins provided with a toxic moiety are preferably used in selectively modulating biological processes.
Composition and uses thereof
Arborvitae Health And Wellbeing Pty. Ltd.
June 07, 2018 - N°20180153970

The invention relates to compositions comprising pinus pinaster stem bark extract, papain, and aloe vera extract, and methods of manufacturing same. There are also described methods of treating or preventing a variety of conditions, including treating or preventing elevated blood glucose, pre-diabetes, type 2 diabetes, autoimmune diseases, reducing or decreasing inflammation, treating or preventing diseases characterised by elevated levels of inflammation, ...
Inhibition of expansion and function of pathogenic age-associated b cells and use for the prevention ...
June 07, 2018 - N°20180153922

The current invention also provides targets for drug development and basic research for autoimmune diseases and other lymphoproliferative and chronic inflammatory disorders.. .
Fused bicyclic pyrimidine derivatives and uses thereof
Dana-farber Cancer Institute, Inc.
June 07, 2018 - N°20180153894

The present invention provides novel compounds of formula (i), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating or preventing proliferative diseases (e.g., cancers (e.g., lung cancer, breast cancer, leukemia, lymphoma, melanoma, multiple myeloma, ewing's sarcoma, ...
Immune Diseases Patent Pack
Download 177+ patent application PDFs
Immune Diseases Patent Applications
Download 177+ Immune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Immune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Novel proteins specific for cd137
Pieris Pharmaceuticals Gmbh
May 31, 2018 - N°20180148484

The present disclosure provides human lipocalin muteins that bind cd137 and can be used in pharmaceutical applications, for example, as anti-cancer agents and/or immune modulators for the treatment or prevention of human diseases such as cancer, infectious diseases, and autoimmune diseases. The present disclosure also concerns methods of making cd137 binding lipocalin muteins described herein as well as compositions ...
Methods and compositions for the treatment of cancer or other diseases
City Of Hope
May 24, 2018 - N°20180142239

The present invention relates to methods and compositions for the treatment of diseases, including cancer, infectious diseases and autoimmune diseases. The present invention also relates to methods and compositions for improving immune function.
Composition enriched in anti-a and/or anti-b polyclonal immunoglobulins for use in the treatment of ...
Laboratoire Francais Du Fractionnement Et Des Biotechnologies
May 24, 2018 - N°20180142036

The invention relates to a composition strongly enriched with anti-a and/or anti-b polyclonal immunoglobulins, comprising polyclonal human immunoglobulins, characterised in that at least 80 wt.-% of the polyclonal human immunoglobulins present in the composition are anti-a or anti-b polyclonal human immunoglobulins, for use as a drug, particularly in the treatment of polycythemia and/or autoimmune diseases, and in particular ...
Therapeutic cd47 antibodies
Tioma Therapeutics, Inc.
May 24, 2018 - N°20180142019

Provided are anti-cd47 monoclonal antibodies (anti-cd47 mabs) with distinct functional profiles as described herein, methods to generate anti-cd47 mabs, and to methods of using these anti-cd47 mabs as therapeutics for the prevention and treatment of solid and hematological cancers, ischemia-reperfusion injury, cardiovascular diseases, autoimmune diseases, inflammatory diseases or as diagnostics for determining the level of cd47 in tissue samples.. .
Ultra-potent neutralization of cytokines by multispecific antibodies and uses thereof
Institute For Research In Biomedicine
May 24, 2018 - N°20180142014

The present invention provides multispecific antibodies, and antigen binding fragments thereof, that potently neutralize a cytokine and that may thus be useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases. In particular, the present invention provides a multispecific antibody, or an antigen binding fragment thereof, comprising at least two different domains specifically binding to at least ...
Autotaxin inhibitors and uses thereof
National And Kapodistrian University Of Athens
May 24, 2018 - N°20180141965

Novel inhibitors of the enzyme autotaxin are described. The inhibitors contain one or two zinc-binding groups at the appropriate distance, also described are uses thereof, such as for the inhibition of autotaxin activity and the treatment of various conditions (e.g., inflammatory conditions, cancer, obesity, autoimmune diseases)..
Compounds and method for treating autoimmune diseases
May 24, 2018 - N°20180141938

Wherein x and y independently are o or nr1; each r1 is independently h or c1-c6 alkyl; ring a is aryl; each r2 independently is h, alkyl, alkoxy, amide, cyano, halo, haloalkyl, hydroxyalkyl, heteroalkyl, heterocyclyl, sulfonyl, sulfonamide, or two r2 groups, taken together with the atom or atoms to which they are attached, combine to form a 4-10 membered ...
Targeted nanocarriers for targeted drug delivery of gene therapeutics
Rodos Biotarget Gmbh
May 24, 2018 - N°20180140717

A targeted nanocarriers also termed nanomedicines and methods of preferentially, or actively, targeting and delivering a tool for gene transfer or genome editing (i.e., a plasmid or a restriction enzyme such as a zinc finger nuclease, a crispr/cas system, or a talen) or a tool for gene silencing or post-transcriptional regulation of gene expression (i.e., a microrna, ...
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