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Immune Diseases

Immune Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Anti-cd52 antibodies
Genzyme Corporation
December 07, 2017 - N°20170349665

Anti-human cd52 antibodies and antigen-binding fragments thereof are provided. Also provided are isolated nucleic acids, recombinant vectors and host cells for making the antibodies and fragments. The antibodies and fragments can be used in therapeutic applications to treat, for example, autoimmune diseases, cancer, and graft rejection.
Heterocyclic derivatives as rorgamma modulators
Genfit
December 07, 2017 - N°20170349582

The present invention provides novel compounds of formula (i) that are modulators of rorgamma. These compounds, and pharmaceutical compositions comprising the same, are suitable means for treating any disease wherein the modulation of rorgamma has therapeutic effects, for instance in autoimmune diseases, autoimmune-related diseases, inflammatory diseases, fibrotic diseases, or cholestatic diseases.
Composition for alleviating nephrotoxicity caused by immunosuppressive drug, comprising metformin, and composition for preventing or ...
The Catholic University Of Korea Industryacademic Cooperation Foundation
December 07, 2017 - N°20170348256

Provided is a composition for alleviating nephrotoxicity caused by an immunosuppressive drug, including metformin, and a composition for preventing or treating an immune disease, including the same. Further, the composition provided can be useful in improving a treatment effect on diseases requiring immunosuppression by effectively alleviating a decline in renal function caused due to side effects of conventional immunosuppressive drugs, ...
Immune Diseases Patent Pack
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Immune Diseases Patent Applications
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inventor
  • 177+ full patent PDF documents of Immune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Hydrophilic external gel formulation capable of enhancing skin permeability of tacrolimus
Chung-ang University Industry-academic Cooperation Foundation
November 30, 2017 - N°20170340558

The present invention relates to a formulation for external application to the skin containing tacrolimus, which is a poorly soluble drug used as a second therapeutic agent for atopic dermatitis and, more specifically, to a composition of a hydrophilic external gel formulation capable of enhancing skin permeability of tacrolimus, and a preparation method therefor. The hydrophilic external gel formulation loaded ...
Diaryl macrocycles as modulators of protein kinases
Tp Therapeutics, Inc.
November 23, 2017 - N°20170334929

The present invention relates to certain diaryl macrocyclic compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating cancer, pain, neurological diseases, autoimmune diseases, and inflammation.
Crystalline forms of a bruton's tyrosine kinase inhibitor
Pharmacyclics Llc
November 23, 2017 - N°20170334921

Described herein is the bruton's tyrosine kinase (btk) inhibitor 1-((r)-3-(4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the btk inhibitor, as well as methods of using the btk inhibitor, alone or in combination with other ...
Immune Diseases Patent Pack
Download 177+ patent application PDFs
Immune Diseases Patent Applications
Download 177+ Immune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Immune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Antioxidant composition containing extracellular polysaccharide produced using ceriporia lacerata as active ingredient
Fugenbio Co., Ltd.
November 23, 2017 - N°20170333501

The present invention relates to an antioxidant composition containing an extracellular polysaccharide produced using ceriporia lacerata, or a mycelium culture of ceriporia lacerata comprising the same, or a dry powder or an extract thereof as an active ingredient. The composition can be used as an antioxidant for preventing or treating various diseases such as brain diseases such as stroke, parkinson's ...
Pharmaceutical composition for preventing or treating immune diseases or inflammatory diseases, containing biguanide derivative compound ...
The Catholic University Of Korea Industry-academic Cooperation Foundation
November 23, 2017 - N°20170333370

The present invention relates to a biguanide derivative compound capable of effectively preventing and treating immune diseases. The biguanide-based derivative compound according to the present invention inhibits the generation of il-17 and tnf-α, which are inflammatory cytokines, increases the activity of regulatory t cells having an immunomodulatory function, and exhibits excellent therapeutic effects in animal models of immune ...
Core-shell particle formulation for delivering multiple therapeutic agents
Amrita Vishwa Vidyapeetham
November 23, 2017 - N°20170333365

A core-shell particle formulation for delivering multiple therapeutic agents is disclosed. More particularly, the formulation comprising protein-protein core-shell particle configured to independently release therapeutic agents from the core and the shell. Moreover, the core-shell particle bearing therapeutic agents enable treatment against the diseases such as cancer, inflammatory and auto-immune diseases.
Molecules that selectively activate regulatory t cells for the treatment of autoimmune diseases
Delinia, Inc.
November 16, 2017 - N°20170327555

This invention provides for a fusion protein between an il2αβγ selective agonist protein (il2 selective agonist) and a igg fe protein. The il2 selective agonist moiety provides a therapeutic activity by selectively activating the il2αβγ form of the receptor, thus selectively stimulating tregs. The fe moiety provides a ...
Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and ...
Nuevolution A/s
November 16, 2017 - N°20170327503

Disclosed are compounds active towards nuclear receptors, pharmaceutical compositions containing the compounds and use of the compounds in therapy.
Inhibitors of cyclin-dependent kinase 7 (cdk7)
Nuevolution A/s
November 16, 2017 - N°20170327496

The present invention provides novel compounds of formula (i) and pharmaceutically acceptable salts, solvates, hydrates, tautomers, stereoisomers, isotopically labeled derivatives, and compositions thereof. Also provided are methods and kits involving the compounds or compositions for treating or preventing proliferative diseases (e. G., cancers (e. G., leukemia, melanoma, multiple myeloma), benign neoplasms, angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in ...
Methods of treating autoimmune diseases
Genzyme Corporation
November 16, 2017 - N°20170326203

Novel methods for treating patients with autoimmune diseases are disclosed. The methods of the invention include first depleting circulating lymphocytes in the mammal, e. G., by administering anti-thymocyte antibody, and then, during the course of repopulation, administering to the mammal a therapeutically effective amount of latent tgf-β and/or another agent that promotes expansion of regulatory t cells. ...
Immune Diseases Patent Pack
Download 177+ patent application PDFs
Immune Diseases Patent Applications
Download 177+ Immune Diseases-related PDFs
For professional research & prior art discovery
inventor
  • 177+ full patent PDF documents of Immune Diseases-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Therapeutic agent for autoimmune diseases comprising pd-1 agonist
Ono Pharmaceutical Co., Ltd.
November 09, 2017 - N°20170320949

Provided is a prophylactic, symptom progress-suppressive, and/or therapeutic agent for an autoimmune disease. The agent lowers the risk of infections and reduces the burden of administration to patients. The prophylactic, symptom progress-suppressive, and/or therapeutic agent includes a pd-1 agonist as an active ingredient and is administered (a) 1 to 10 times within one month from the first administration, (b) in ...
Receptor trem (triggering receptor expressed on myeloid cells) and uses thereof
Novo Nordisk A/s
November 09, 2017 - N°20170320946

Novel activating receptors of the ig super-family expressed on human myeloid cells, called trem(s) (triggering receptor expressed on myeloid cells) are provided. Specifically, two (2) members of trems, trem-1 and trem-2 are disclosed. Trem-1 is a transmembrane glycoprotein expressed selectively on blood neutrophils and a subset of monocytes but not on lymphocytes and other cell types and is upregulated by ...
Novel aniline derivative, pharmaceutical composition containing same, and use thereof
Novo Nordisk A/s
November 09, 2017 - N°20170320821

[solution] the present invention provides a compound represented by the general formula (i): (in the formula, rl, r2 and r3 are each a hydrogen atom, a halogen atom, a c1-6 alkyl group, a halo c1-6 alkyl group or the like, r4 is a c1-6 alkyl group or the like, r5 is a c1-6 alkyl group or ...
Compositions comprising bacterial strains
4d Pharma Research Limited
November 09, 2017 - N°20170319634

The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
Immunosuppressive blood cells and methods of producing the same
Universitatsklinikum Heidelberg
November 09, 2017 - N°20170319619

The present invention refers to a method of producing immunosuppressive bleed cells that can be used for the treatment of autoimmune diseases, in particular multiple sclerosis, organ graft rejection and graft-versus-host disease.
Isoquinolin-3-yl carboxamides and preparation and use thereof
Universitatsklinikum Heidelberg
November 02, 2017 - N°20170313681

Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of wnt pathway signaling (e. G., cancer, abnormal cellular proliferation, angiogenesis, alzheimer's disease, lung disease, inflammation, auto-immune diseases and osteoarthritis), the modulation of cellular events mediated ...
Compositions and methods for treating cancer, inflammatory diseases and autoimmune diseases
Gilead Sciences, Inc.
October 26, 2017 - N°20170306050

The present disclosure provides compositions and methods of use comprising a matrix metalloproteinase-9 (mmp9) binding protein, alone or in combination with one or more additional therapeutic agents for the treatment or prevention of diseases and conditions.
Methods of treating autoimmune disease using a domain antibody directed against cd40l
Bristol-myers Squibb Company
October 26, 2017 - N°20170306034

Methods of treating autoimmune diseases, such as primary immune thrombocytopenia (itp), solid organ transplant rejection, graft-related disease, pemphigus vulgaris, systemic sclerosis, and myasthenia gravis using antibody polypeptides that specifically bind human cd40l are provided. The antibody polypeptides do not activate platelets. The methods may comprise at least one administration cycle comprising one dose of the antibody polypeptide. The dose ...
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