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Immune Disease patents



      
           
This page is updated frequently with new Immune Disease-related patent applications. Subscribe to the Immune Disease RSS feed to automatically get the update: related Immune RSS feeds. RSS updates for this page: Immune Disease RSS RSS


Date/App# patent app List of recent Immune Disease-related patents
09/11/14
20140256942
 Benzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor patent thumbnailBenzoimidazol-2-yl pyrimidine modulators of the histamine h4 receptor
Benzoimidazol-2-yl pyrimidines, purification methods for the same, and pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by h4 receptor activity, including allergy, asthma, autoimmune diseases, and pruritus.. .
09/11/14
20140256759
 Kinase inhibitor and method for treatment of related diseases patent thumbnailKinase inhibitor and method for treatment of related diseases
Disclosed is a compound of (aminophenylamino) pyrimidyl benzamides and a synthesis method thereof. The compound has btk-inhibition activity and can be used to treat autoimmune diseases, heteroimmune diseases, cancers or thromboembolic diseases..
09/11/14
20140256739
 Method of treatment patent thumbnailMethod of treatment
The present invention relates to a method of treating t cell mediated inflammatory immune diseases or t cell mediated hypersensitivity diseases, which comprises administering to a human in need thereof an effective amount of a compound which inhibits ezh2 and/or ezh1, or a pharmaceutically acceptable salt thereof.. .
09/11/14
20140256734
 Pyridinyl and fused pyridinyl triazolone derivatives patent thumbnailPyridinyl and fused pyridinyl triazolone derivatives
Or pharmaceutically acceptable salts thereof, wherein r1, r2, r3, and r4 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of formula 1, to pharmaceutical compositions which contain them, and to their use for treating type i hypersensitivity reactions, autoimmune diseases, inflammatory disorders, cancer, non-malignant proliferative disorders, and other conditions associated with btk..
09/11/14
20140256645
 Extract and peptides derived from oryza sativa japonica group and uses thereof patent thumbnailExtract and peptides derived from oryza sativa japonica group and uses thereof
The invention relates to isolated peptides derived from oryza sativa japonica group, pharmaceutical compositions comprising same, and uses thereof for treating, preventing, ameliorating, and/or delaying the onset of inflammatory and/or neuroinflammatory and/or autoimmune diseases or conditions and in particular multiple sclerosis. The invention further relates to extracts from oryza sativa japonica group and use thereof as a dietary supplement or in a pharmaceutical composition for treating, preventing, ameliorating, and/or delaying the onset of inflammatory, and/or inflammatory, neuroinflammatory and/or autoimmune diseases or conditions.
09/11/14
20140256592
 Determining responsiveness of autoimmune patients to dmard treatment patent thumbnailDetermining responsiveness of autoimmune patients to dmard treatment
The invention is directed to a method of screening patients suffering from an autoimmune disease for responsiveness to treatment with a disease modifying anti-rheumatic drug, or dmard. In some embodiments the method of the invention comprises the steps of (a) measuring an igh clonotype profile from b-cells in a sample of tissue affected by the autoimmune disease, the igh clonotype profile including igh clonotypes, igg clonotypes, and igd clonotypes; and (b) classifying a patient as being more likely to respond to dmard treatment, whenever the patient has, with respect to reference levels characteristic of normal tissue, elevated igh concentration, elevated igg fraction, and reduced igd fraction..
09/11/14
20140255429
 Methods of treating autoimmune diseases with dll4 antagonists patent thumbnailMethods of treating autoimmune diseases with dll4 antagonists
The present invention provides methods of treating a disease or disorder, in which increasing the number of regulatory t cell (treg) is beneficial, by administering to a subject suffering from such a disease or disorder a therapeutically effective amount of dll4 antagonists that block dll4-notch signal pathways, thereby increasing the number of treg. Diseases or disorders treatable by the methods of the invention include autoimmune diseases or disorders, such as multiple sclerosis (ms), diabetes, and the like.
09/11/14
20140255406
 Anti-tnf-anti-il-17 bispecific antibodies patent thumbnailAnti-tnf-anti-il-17 bispecific antibodies
Bispecific antibodies are provided that specifically bind both tumor necrosis factor alpha (tnfα) and interleukin-17 (il-17). The bispecific antibodies of the invention are useful for treating various autoimmune diseases, including rheumatoid arthritis (ra), psoriatic arthritis (psa), and ankylosing spondylitis (as)..
09/11/14
20140255393
 Compositions and methods for autoimmune disease patent thumbnailCompositions and methods for autoimmune disease
Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (scnp), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease.. .
09/11/14
20140255374
 Compositions and methods for treatment of autoimmune and other disease patent thumbnailCompositions and methods for treatment of autoimmune and other disease
Provided are methods relating to the use of cdp-therapeutic agent conjugates for the treatment of autoimmune disease, inflammatory disease, or cancer. Also provided are cdp-therapeutic agent conjugates, particles comprising cdp-therapeutic agent conjugates, and compositions comprising cdp-therapeutic agent conjugates..
09/11/14
20140255358
Generation of immunosuppressive myeloid cells using pge2
Therapies effective for the treatment and prevention of autoimmune diseases, chronic inflammatory diseases, transplant rejection or graft versus host disease (gvh), using prostaglandin (pg), alternative agonists of pg receptors, ep2 or ep4, or other activators of adenylate cyclase/camp/pka/creb signaling pathway are disclosed herein. These methods include the administration of a therapeutically effective amount of myeloid cells pre-treated ex vivo with the above-mentioned factors, or the in vivo administration of such agents in combination with the factors attracting myeloid precursor cells, such as myeloid cell-attracting chemokines or their inducers.
09/11/14
20140255341
Tumor selective chemokine modulation
Therapies effective for the treatment and prevention of cancer and other diseases are disclosed. These methods include the administration of therapeutically effective amounts of agents that increase the local production of effector cell-attracting chemokines within tumor lesions, with concomitant suppression of local production of undesirable chemokines that attract regulatory t(reg) cells.
09/04/14
20140249089
Methods of treating disease with random copolymers
The invention relates to novel methods and kits for treating or preventing disease through the administration of random copolymers. The invention also relates to the treatment of autoimmune diseases, such as multiple sclerosis, and to the administration of random copolymers in treatment regimen comprising formulations that are administered at intervals greater than 24 hours, or to sustained release formulations which administer the copolymer over a period greater than 24 hours.
08/28/14
20140243382
Inhibitors of c-fms kinase
Wherein z, x, j, r2 and w are set forth in the specification, as well as solvates, hydrates, tautomers and pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase. Methods of treating autoimmune diseases; and diseases with an inflammatory component; treating metastasis from ovarian cancer, uterine cancer, breast cancer, prostate cancer, lung cancer, colon cancer, stomach cancer, hairy cell leukemia; and treating pain, including skeletal pain caused by tumor metastasis or osteoarthritis, or visceral, inflammatory, and neurogenic pain; as well as osteoporosis, paget's disease, and other diseases in which bone resorption mediates morbidity including rheumatoid arthritis, and other forms of inflammatory arthritis, osteoarthritis, prosthesis failure, osteolytic sarcoma, myeloma, and tumor metastasis to bone with the compounds of formula i, are also provided..
08/28/14
20140243355
Inhibitors of bruton's tyrosine kinase
Disclosed herein are compounds that form covalent bonds with bruton's tyrosine kinase (btk). Also described are irreversible inhibitors of btk.
08/28/14
20140242185
Method of enhancing health of a person
A method of enhancing health of a person includes administering stable water clusters to persons having an autoimmune disease, pain, a chronic disease, a mental disease, a genetic disease from malfunction of a normal dna, being an athlete for improving his performance and alleviating soreness, suffering from overworking, stress and toxins etc., by drinking a solution containing stable water clusters, swallowing small objects which contain the stable water clusters, putting a topical cream which contains the stable water clusters on skin, breathing the stable water clusters through mouth, putting drops which contain the stable water clusters into eyes, ears or nose, cleaning colon with solution that contains the stable water clusters, eating food that contains the stable water clusters, injecting solution that contain the stable water clusters into blood vessel etc.. .
08/28/14
20140242101
Pd-l1 based immunotherapy
The present invention relates to the field of prophylaxis and therapy of clinical conditions including cancer, autoimmune diseases and infectious diseases. In particular there is provided vaccine compositions comprising pd-l1 or peptide fragments thereof that are capable of eliciting immune responses useful in treatment of cancer, autoimmune diseases or infectious diseases..
08/28/14
20140242094
Methods related to tim 3, a th1-specific cell surface molecule, for activating antigen presenting cells
The present invention provides compositions and methods useful for promoting or reducing t-cell trafficking to a target tissue. Also provided are compositions and methods useful for promoting or inhibiting antigen-presenting cell (apc) activation.
08/28/14
20140242062
Modified proteases that inhibit complement activation
Provided are methods for and compounds for modulating the complement system. In particular, compounds are provided that inhibit complement activation and compounds are provided that promote complement activation.
08/28/14
20140242058
St6gal i mediated modulation of hematopoiesis
Provided are methods for reducing haematocytes in an individual. The method involve administering to an individual a composition that contains recombinant a2,6-sialyltransferase (st6gal i).
08/28/14
20140242049
Mutant ctla4 gene transfected t cell and composition including same for anticancer immunotherapy
A transformed t-cell for t-cell therapy, and a composition including the same for anticancer immunotherapy. More particularly, the transformed t-cell is characterized by the transfection of a gene for coding a chimera protein.
08/21/14
20140235888
(z)-2-cyano-3-hydroxy-but-2-enoic acid-(4'-trifluormethylphenyl)-amide tablet formulations with improved stability
The invention relates to solid pharmaceutical compositions comprising (z)-2-cyano-3-hydroxy-but-2-enoic acid-(4′-trifluoromethylphenyl)-amide, as well as a process for the preparation of the same, methods of using such compositions to treat subjects suffering from autoimmune diseases in particular systemic lupus erythematosus or chronic graft-versus-host disease, multiple sclerosis or rheumatoid arthritis.. .
08/21/14
20140235829
Compositions and methods for regulation of tumor necrosis factor-alpha
The present invention relates to compositions and methods relating to an interleukin 18-inducible cytokine termed tumor necrosis factor-alpha inducing factor (taif) or interleukin-32 (il-32). In particular, the present invention provides compositions and methods for treating autoimmune diseases and cancer, in part by regulation of tumor necrosis factor-alpha expression..
08/21/14
20140235719
Pharmaceutical composition for the prevention or treatment of inflammatory diseases or immune diseases containing ramalin
The present invention relates to the novel use (anti-inflammatory activity) of ramalin isolated from the antarctic lichen ramalina terebrata, and more specifically to a pharmaceutical composition containing ramalin as an active ingredient. Ramalin of the invention is a compound derived from natural material, has no toxicity or side effects, and inhibits the expression of inducible nitric oxide synthase (inos) in the transcription stage to significantly inhibit the production of nitric oxide (no) that is a key mediator of inflammatory responses.
08/21/14
20140235591
Bicyclic compounds
And/or a salt thereof; wherein r is —oh or —op(o)(oh)2. Also disclosed are methods of using such compounds as selective agonists for g protein-coupled receptor s1p1, and pharmaceutical compositions comprising such compounds.
08/21/14
20140235454
Monitoring health and disease status using clonotype profiles
There is a need or improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer, especially lymphoid neoplasms, such as lymphomas and leukemias. Provided herein are methods for using dna sequencing to identify personalized, or patient-specific biomarkers in patients with lymphoid neoplasms, autoimmune disease and other conditions.


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Immune Disease topics: Immune Disease, Autoimmune, Autoimmune Disease, Immune Diseases, Autoimmune Diseases, Immune Disorder, Transplant, Autoimmune Disorders, Type 1 Diabetes, Autoimmune Disorder, Proliferative Disorder, Signs And Symptoms, Proliferative, Antagonist, Recurrence

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This listing is a sample listing of patent applications related to Immune Disease for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Immune Disease with additional patents listed. Browse our RSS directory or Search for other possible listings.
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