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Immune Disease

Immune Disease-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Markers of alzheimers disease
Immunoclin Ltd.
January 11, 2018 - N°20180010182

The use of markers that participate in inflammatory processes and are associated cytokines in the diagnosis, treatment or prophylaxis of diseases is disclosed. Specifically, cytokines are used to diagnose or treat non-neoplastic or non-leukaemic diseases such as autoimmune diseases or neurodegenerative disorders by the process of taking a dna bearing sample from a subject animal and analysing the sample to ...
Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof
Imstem Biotechnology, Inc.
January 11, 2018 - N°20180010098

The present invention relates to methods of generating and expanding hitman embryonic stem cell derived mesenchymal-like stem/stromal cells. These hes-mscs are characterized at least in part by the low level of expression of il-6. These cells are useful for the prevention and treatment of t cell related autoimmune disease, especially multiple sclerosis, as well as for delivering agents across ...
Methods for the treatment of disease using immunoglobulins having fc regions with altered affinities for ...
Macrogenics, Inc.
January 11, 2018 - N°20180009902

The present invention relates to methods of treating or preventing cancer and other diseases using molecules, particularly polypeptides, more particularly immunoglobulins (e. G., antibodies), comprising a variant fc region, wherein said variant fc region comprises at least one amino acid modification relative to a wild-type fc region, which variant fc region binds an fcγr that activates a ...
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Immune Disease Patent Applications
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  • 255+ full patent PDF documents of Immune Disease-related inventions.
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  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Heterocyclic compounds as pi3k-y inhibitors
The Trustees Of Dartmouth College
January 11, 2018 - N°20180009816

Or pharmaceutically acceptable salts or stereoisomers thereof, which are inhibitors of pi3k-γ which are useful for the treatment of disorders such as autoimmune diseases, cancer, cardiovascular diseases, and neurodegenerative diseases.
Heterocyclic compounds and use thereof
National Health Research Institutes
January 11, 2018 - N°20180009786

Heterocyclic compounds of formula (i) shown herein. Also disclosed are pharmaceutical compositions containing the heterocyclic compounds and methods of using the heterocyclic compounds to mobilize hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation. Further provided are methods for treating tissue injury, cancer, inflammatory disease, and autoimmune disease with the heterocyclic compounds.
Quinazoline and quinoline compounds and uses thereof
Millennium Pharmaceuticals, Inc.
January 11, 2018 - N°20180009784

This invention provides compounds of formula (i) or a pharmaceutically acceptable salt thereof, wherein t, j, r, r4, rq, o, ra, w and rb and subsets thereof are as described in the specification. The compounds are inhibitors of nampt and are thus useful for treating cancer, inflammatory conditions, and/or t-cell mediated autoimmune disease.
Immune Disease Patent Pack
Download 255+ patent application PDFs
Immune Disease Patent Applications
Download 255+ Immune Disease-related PDFs
For professional research & prior art discovery
inventor
  • 255+ full patent PDF documents of Immune Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Covalent inhibitors of cdk-7
Gvk Biosciences Private Limited
January 11, 2018 - N°20180008604

Wherein r0, r1, r2, r3, r4, r5, and l are defined herein. Also disclosed is a method for treating a neoplastic disease, autoimmune disease, and inflammatory disorder with these compounds.
Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders
Gvk Biosciences Private Limited
January 04, 2018 - N°20180007043

Useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of il6 or interferons.
Method of assessing rheumatoid arthritis by measuring anti-ccp and anti-pik3cd
Roche Diagnostics Operations, Inc.
January 04, 2018 - N°20180003710

The present invention relates to a method aiding in the assessment of rheumatoid arthritis (“ra”). The method is used in assessing ra in vitro. It is practiced by analyzing biochemical markers, comprising measuring the concentration of anti-ccp and anti-pik3cd and correlating the concentrations determined to the absence or presence of ra. The invention also relates ...
Cyclic dinucleotides useful for the treatment of inter alia cancer
Roche Diagnostics Operations, Inc.
January 04, 2018 - N°20180002369

Or a pharmaceutically acceptable salt and tautomers thereof, compositions, combinations and medicaments containing said compounds and processes for their preparation. The invention also relates to the use of said compounds, combinations, compositions and medicaments, in the treatment of diseases and conditions in which modulation of sting (stimulator of interferon genes) is beneficial, for example inflammation, allergic and autoimmune diseases, infectious ...
Novel compound useful for the treatment of degenerative and inflammatory diseases
Galapagos Nv
January 04, 2018 - N°20180000831

A novel compound able to inhibit jak is disclosed, this compound may be prepared as a pharmaceutical composition, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/...
[1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds
Galapagos Nv
January 04, 2018 - N°20180000790

Or a salt thereof, wherein r1, r2, r3, r4, r5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
Interferon alpha antibodies and their uses
E. R. Squibb & Sons, L.l.c.
December 28, 2017 - N°20170369568

The present invention provides isolated anti-interferon alpha monoclonal antibodies, particularly human monoclonal antibodies, that inhibit the biological activity of multiple interferon (ifn) alpha subtypes but do not substantially inhibit the biological activity of ifn alpha 21 or the biological activity of either ifn beta or ifn omega. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also ...
Immune Disease Patent Pack
Download 255+ patent application PDFs
Immune Disease Patent Applications
Download 255+ Immune Disease-related PDFs
For professional research & prior art discovery
inventor
  • 255+ full patent PDF documents of Immune Disease-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Compositions comprising bacterial strains
4d Pharma Research Limited
December 28, 2017 - N°20170368110

The invention provides compositions comprising bacterial strains for treating and preventing inflammatory and autoimmune diseases.
Pan-elr+ cxc chemokine antibodies
Eli Lilly And Company
December 21, 2017 - N°20170362315

Antibodies are provided that specifically bind seven human elr+ cxc chemokines. The antibodies of the invention are useful for treating various inflammatory/autoimmune diseases, such as inflammatory bowel disease (ibd), plaque psoriasis, and palmoplantar pustulosis; and cancer, such as renal cancer or ovarian cancer.
Use of binding molecule specifically binding to precursor of brain-derived neurotrophic factor
Shanghai Yile Biotechnology Co., Ltd.
December 21, 2017 - N°20170362313

Disclosed herein is use of a binding molecule which specifically binds to a precursor of brain-derived neurotrophic factor (probdnf). The binding molecule for probdnf, especially a monoclonal antibody against probdnf, can be used to prevent, mitigate or treat autoimmune diseases.
Soluble universal adcc-enhancing synthetic fusion gene and peptide technology and its use thereof
1globe Biomedical Co., Ltd.
December 21, 2017 - N°20170362299

Novel synthetic biology-based adcc technologies are provided that enhance or enable adcc responses, for example, through a rationally-designed soluble universal adcc enhancer protein (suaep) where a high-affinity cd3-binding domain is fused to a high-affinity fc-binding domain. The suaep technology can be used to prevent or treat cancers, infectious, inflammatory or autoimmune diseases, and other diseases where elimination of diseased ...
4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors
Celgene Corporation
December 21, 2017 - N°20170362240

Compounds of formula i: and stereoisomers and pharmaceutically acceptable salts and solvates thereof in which r1, r2, r3 and r4 have the meanings given in the specification, are inhibitors of one or more jak kinases and are useful in the treatment of jak kinase-associated diseases and disorders, such as autoimmune diseases, inflammatory diseases, rejection of transplanted organs, tissues and cells, ...
Novel compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders
Celgene Corporation
December 21, 2017 - N°20170362227

The present invention relates to compounds inhibiting autotaxin (npp2 or enpp2), methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, proliferative diseases, inflammatory diseases, autoimmune diseases, respiratory diseases, cardiovascular diseases, neurodegenerative diseases, dermatological disorders, and/or abnormal angiogenesis associated diseases by administering ...
Carbazole derivatives
Bristol-myers Squibb Company
December 21, 2017 - N°20170362176

Disclosed are compounds of formula (i): (i) or a salt thereof, wherein q, r1a, r1b, r2a, r2b, r3, r4, r5a, r5b, r6a, r6c, r7a, r7b, r7c, and r7d are defined herein. Also disclosed are methods of using such compounds as inhibitors of bruton's tyrosine kinase (btk), and pharmaceutical ...
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