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Immune Disease patents



      
           
This page is updated frequently with new Immune Disease-related patent applications. Subscribe to the Immune Disease RSS feed to automatically get the update: related Immune RSS feeds. RSS updates for this page: Immune Disease RSS RSS



Date/App# patent app List of recent Immune Disease-related patents
08/27/15
20150241448 
 Lanthionine synthetase component c-like proteins as molecular targets for preventing and treating diseases and disorders patent thumbnailLanthionine synthetase component c-like proteins as molecular targets for preventing and treating diseases and disorders
The present invention relates to the field of medical treatments for diseases and disorders. More specifically, the present invention relates to the use of the lanthionine synthetase component c-like (lancl) proteins as therapeutic targets for novel classes of anti-inflammatory, immune regulatory and antidiabetic drugs.
Virginia Tech Intellectual Properties, Inc.


08/27/15
20150239974 
 Humanized rfb4 anti-cd22 antibody patent thumbnailHumanized rfb4 anti-cd22 antibody
Disclosed are humanized rfb4 antibodies or antigen-binding fragments thereof. Therapy of b-cell associated diseases, such as b-cell malignancies, autoimmune disease and immune dysfunction disease.
Immunomedics, Inc.


08/27/15
20150239957 
 Ig-pconsensus gene vaccination protects from antibody-dependent immune pathology in autoimmune disease patent thumbnailIg-pconsensus gene vaccination protects from antibody-dependent immune pathology in autoimmune disease
The disclosure provides a fusion polypeptide and compositions useful for treating autoimmune diseases and disorders. The fusion polypeptide comprises a first domain comprising a self antigen which is a conserved sequence found in t cell determinants in the fr1/cdr1 region of vh of human and murine igg antibodies, particularly seq id no:2 or an antigenic fragment thereof; and a second domain comprising a heterologous polypeptide or small molecule..
Università Degli Studi Di Genova


08/27/15
20150239897 
 Pyrrolopyrimidine compounds as kinase inhibitors patent thumbnailPyrrolopyrimidine compounds as kinase inhibitors
Disclosed herein are compounds that form covalent bonds with bruton's tyrosine kinase (btk). Also described are irreversible inhibitors of btk.
Pharmacyclics, Inc.


08/27/15
20150239886 
 Substituted fused tricyclic compounds, compositions, and medicinal applications thereof patent thumbnailSubstituted fused tricyclic compounds, compositions, and medicinal applications thereof
The compounds of the present invention are useful in the treatment, prevention or suppression of diseases and disorders mediated by jak activity. Such conditions include, but not limited to, arthritis, alzheimer's disease, autoimmune thyroid disorders, cancer, diabetes, leukemia, t-cell prolymphocytic leukemia, lymphoma, myleoproliferation disorders, lupus, multiple myeloma, multiple sclerosis, osteoarthritis, sepsis, psoriatic arthritis, prostate cancer, t-cell autoimmune disease, inflammatory diseases, chronic and acute allograft transplant rejection, bone marrow transplant, stroke, asthma, chronic obstructive pulmonary disease, allergy, bronchitis, viral diseases, or type i diabetes, complications from diabetes, rheumatoid arthritis, asthma, crohn's disease, dry eye, uveitis, inflammatory bowel disease, organ transplant rejection, psoriasis and ulcerative colitis.

08/27/15
20150238583 
 Dna vaccines encoding heat shock proteins patent thumbnailDna vaccines encoding heat shock proteins
A method of treating a t cell-mediated inflammatory autoimmune disease by administering to an individual in need thereof an immunogenic composition comprising a recombinant construct of a nucleic acid sequence encoding heat shock protein 90 (hsp 90), or an active fragment thereof, wherein the nucleic acid sequence is operatively linked to one or more transcription control sequences. The disease is other than insulin dependent diabetes mellitus (iddm) or rheumatoid arthritis.
Alma Bio Therapeutics


08/27/15
20150238548 
 Lactobacillus strain, composition and use thereof for treating syndromes and related complications of autoimmune diseases patent thumbnailLactobacillus strain, composition and use thereof for treating syndromes and related complications of autoimmune diseases
The present invention is related to a lactobacillus strain, composition and use thereof for treating autoimmune disease and related complications. The composition comprises at least one isolate of lactobacillus paracasei strain gmnl-32, l.
Genmont Biotech Incorporation


08/27/15
20150238493 
 Medicament for treating peripheral neuropathies patent thumbnailMedicament for treating peripheral neuropathies
The invention provides a method for treatment of the diseases in a human by identifying the human as one suffering from a herpes simplex virus (hsv), and then administering to the human the compound anti-hsv agent or a pharmaceutically acceptable salt thereof. The diseases include dermatosis and non-dermatosis, wherein the dermatosis include acnes, impetigo, pyoderma gangrenosum, chilblains and psoriasiform, asteatotic dermatitis, ichthyosis, lichen simplex chronicus (neurodermatitis, prurigo), seborrhoeic dermatitis, rosacea, perioral dermatitis, epidermal cyst, wound ulcer, discoid lupus erythematosus, vitiligo, alopecia, diagnostic criteria of some autoimmune diseases such as systemic lupus erythematosus or diabetic skin complications, wherein the non-dermatosis include glomerulonephritis, arthritis, crohn's disease, ulcerative colitis, myelodysplasia, multiple myeloma, demyelinating disease, parkinson's disease, anemia, cytopenia those among the diagnostic criteria..

08/27/15
20150238445 
 Composition using metformin for preventing or treating immune diseases including lupus patent thumbnailComposition using metformin for preventing or treating immune diseases including lupus
The present invention relates to a composition for preventing or treating immune diseases through the suppression of b cell activity induced by metformin. More particularly, the present invention relates to a composition comprising a metformin compound or a pharmaceutically acceptable salt thereof as an active ingredient for preventing or treating immune diseases, wherein the composition is characterized by suppression or reduction of b cell activity which is a cause of disease.
Catholic University Industry Academic Cooperation Foundation


08/20/15
20150232521 
 Peptides and methods for inducing cell death patent thumbnailPeptides and methods for inducing cell death
The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein.
Los Angeles Biomedical Research Institute At Harbor-ucla Medical Center


08/20/15
20150231281 

Inflammation imaging and therapy


An imaging agent comprising a conjugate of an oligosaccharide moiety with an imaging moiety. The oligosaccharide is lewis a or lewis b or a mimetic thereof, or a pharmaceutically acceptable salt or pegylated form of lewis a or lewis b or its mimetics.
Isis Innovation Limited


08/20/15
20150231234 

Use of anti-cd1 antibodies for the modulation of immune responses


The invention provides methods for the administration of an anti-cd1 antibody for the treatment or prevention of a variety of disorders, such as autoimmune disease, viral infection, bacterial infection, parasitic infection, infection by a eukaryotic pathogen, allergy, asthma, inflammatory condition, graft versus host disease, graft rejection, immunodeficiency disease, spontaneous abortion, pregnancy, and cancer.. .
Beth Israel Deaconess Medical Center, Inc.


08/20/15
20150231195 

Competitive inhibitors of invariant chain expression and/or ectopic clip binding


The invention relates to methods for modulating the immune function through targeting of clip molecules. The result is wide range of new therapeutic regimens for treating, inhibiting the development of, or otherwise dealing with, a multitude of illnesses and conditions, including autoimmune disease, cancer, alzheimer's disease, allergic disease, transplant and cell graft rejection, hiv infection and other viral, bacterial, and parasitic infection, and aids.
Regents Of The University Of Colorado, A Body Corporate


08/13/15
20150225438 

Suprametallogels and uses thereof


The disclosure provides nanostructures (e.g., nanospheres and nano-paddlewheels) formed through transition metal-ligand (e.g., pd(ii)-, ni(ii)-, or fe(ii)-ligand of formula (a)) coordination and junction self-assembly. The disclosure also provides supramolecular complexes that include the nanostructures connected by divalent linkers y.
Massachusetts Institute Of Technology


08/13/15
20150225398 

Novel salts and pharmaceutical compositions thereof for the treatment of inflammatory disorders


Useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of il6 or interferons.. .

08/13/15
20150224199 

Pharmaceutical compositions for the treatment of inflammatory disorders


Useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving degradation and/or disruption of cartilage homeostasis, congenital cartilage malformations, and/or diseases associated with hypersecretion of il6 or interferons.. .

08/13/15
20150224146 

Cell populations having immunoregulatory activity, isolation and uses


The present invention provides a population of connective tissue derived cells that respond to interferon-gamma (ifn-γ) by expressing indolamine-2,3-dioxygenase (ido) for use in preventing, treating or ameliorating one or more symptoms associated with disorders in which modulation of a subject's immune system is beneficial, including, but not limited to, autoimmune diseases, inflammatory disorders, and immunologically mediated diseases including rejection of transplanted organs and tissues.. .
Consejo Superior De Investigaciones Cientificas


08/13/15
20150224141 

Methods of using small compounds to enhance myeloid derived suppressor cell function for treating autoimmune diseases


Methods for enhancing the suppressive function of myeloid derived suppressor cells (mdscs) for the treatment of autoimmune diseases using small compounds are disclosed. In certain aspects, the small compounds are glatiramer acetate and mitogen activated protein (map) kinase inhibitors.
Icahn School Of Medicine At Mount Sinai


08/06/15
20150218563 

Compositions and methods for modulation of rorgammat functions


The present invention relates to expression of rorγt in cells and tissues and the effect of expression of this gene on proliferation of specific immune cells and in promotion of immune cell aggregates and in induction of il17 producing cells. Furthermore, the invention relates to methods and agents that may decrease function of the gene product (the protein) or expression of this gene in individuals experiencing an inflammatory condition, an autoimmune disease or a food allergy, or any other condition whereby it is desirable to inhibit an immune response.

08/06/15
20150218260 

Interleukin-2 fusion proteins and uses thereof


The present invention generally relates to fusion proteins of immunoglobulins and interleukin-2 (il-2). More particularly, the invention concerns fusion proteins of immunoglobulins and mutant il-2 that exhibit improved properties for use as therapeutic agents, e.g.
Hoffman-la Roche Inc.


08/06/15
20150218239 

Fcrn antagonists and methods of use


Provided are novel fcrn antagonist compositions comprising a variant fc region that binds specifically to fcrn with increased affinity and reduced ph dependence relative to the native fc region. Also provided are fcrn antagonists with enhanced cd16 binding affinity.
The Board Of Regents Of The University Of Texas System


08/06/15
20150218199 

Hydroxylated krn7000 analogue and use thereof


Wherein r1 is a hydrogen atom or a hydroxyl group; two r2 are the same or different and each is a hydrogen atom or a hydroxyl group; r3 is a hydrocarbon group having 8-14 carbon atoms, which optionally has substituent(s); and r4 is a hydrocarbon group having 18-24 carbon atoms, which optionally has substituent(s), or a salt thereof. The invention also provides a method of treating an autoimmune disease or suppressing immunity by administering the aforementioned compound or a salt thereof to a patient in need thereof..

08/06/15
20150216971 

Methods for treating gi syndrome and graft versus host disease


It has been discovered that administering therapeutically effective amounts of an antibiotic that kills gram-negative bacteria, together with an anti-ceramide antibody or anti-ceramide mimetic, treats and prevents an array of diseases mediated by cytolytic t lymphocyte (ctl)-induced killing and/or by damage to endothelial microvasculature, including radiation gi syndrome, cgvhd disease, inflammatory diseases and autoimmune diseases.. .
Sloan Kettering Institute For Cancer Research


08/06/15
20150216908 

Quadri-positive stromal cell (qpsc) population for superior cell protection and immunomodulation


The invention unexpectedly found that an isolated and modified qpsc population has multi-potentiality, including: osteoblasts (bone cells), chondrocytes (cartilage cells), and adipocytes (fat cells). The qpsc population of the invention features a desirable immunomodulation ability, including inducing, enhancing, or suppressing an immune response and thus has potential value in the prevention and/or treatment of various immune diseases/disorders/conditions.
Steminent Biotherapeutics Inc.


08/06/15
20150216876 

Method for treating inflammatory conditions


A method for treating an autoimmune disease in a subject includes administering to the subject a therapeutically effective amount of an agent comprising an imidazole, an estrogen receptor agonist, or pharmaceutically acceptable salts thereof.. .
Novelmed Therapeutics, Inc.


07/30/15
20150210982 

Isolation and use of human regulatory t cells


The present invention provides a new method for isolating and enriching human regulatory t cells. The enriched cells are useful in the treatment of autoimmune disease..
Biogen Idec Ma Inc.


07/30/15
20150210704 

Inhibitors of bruton's tyrosine kinase


This application discloses compounds according to generic formula i: wherein all variables are defined as described herein, which inhibit btk. The compounds disclosed herein are useful to modulate the activity of btk and treat diseases associated with excessive btk activity.
Hoffmann-la Roche Inc.


07/30/15
20150210703 

Imidazopyridazine jak3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases


The present invention provides compounds of formula (i) and pharmaceutically acceptable salts thereof. The formula i compounds inhibit tyrosine kinase activity of jak3, thereby making them useful for the treatment of inflammatory and autoimmune diseases..
Bristol-myers Squibb Company




Popular terms: [SEARCH]

Immune Disease topics: Immune Disease, Autoimmune, Autoimmune Disease, Immune Diseases, Autoimmune Diseases, Immune Disorder, Transplant, Autoimmune Disorders, Type 1 Diabetes, Autoimmune Disorder, Proliferative Disorder, Signs And Symptoms, Proliferative, Antagonist, Recurrence

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