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Hypertension

Hypertension-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof
University Of Texas Board Of Regents
October 12, 2017 - N°20170292159

The present invention provides compositions and methods based on genetic polymorphisms that are associated with cardiovascular diseases, particularly coronary heart disease (especially myocardial infarction) or hypertension. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods ...
Nitric oxide donating carnosine compounds
Nicox Science Ireland
October 12, 2017 - N°20170291920

The present invention relates to nitric oxide donor carnosine derivatives having a great efficacy in reducing elevated intraocular pressure, to processes for their preparation and to their use in the treatment and/or prophylaxis of glaucoma and ocular hypertension.
Methods and apparatus to stimulate the heart
Backbeat Medical, Inc.
October 12, 2017 - N°20170291032

A method and apparatus for treatment of hypertension and heart failure by increasing secretion of endogenous atrial hormones by pacing of the heart. Pacing is done during the ventricular refractory period resulting in premature atrial contraction that does not result in ventricular contraction. Pacing results in the atrial wall stress, peripheral vasodilation, anp secretion. Concomitant reduction of the heart rate ...
Hypertension Patent Pack
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Hypertension Patent Applications
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  • 166+ full patent PDF documents of Hypertension-related inventions.
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Method of treating hypertension
King Saud University
October 12, 2017 - N°20170290871

A method of treating hypertension can include administering to a patient in need thereof a therapeutically effective amount of an extract of matricaria chamomilla l. The extract can be administered orally to the patient in an amount of about 100 mg/kg to about 200 mg/kg.
Treatment of male androgen deficiency symptoms or diseases with sex steroid precursor combined with serm
Endorecherche, Inc.
October 12, 2017 - N°20170290847

Novel methods for prevention, reduction or elimination of the incidence of male androgen deficiency symptoms or diseases including male hypogonadism-associated symptoms and diseases associated with low serum testosterone and/or low dhea or low total androgens in susceptible warm-blooded animals including humans involving administration of an amount of a sex steroid precursor, particularly dehydroepiandrosterone (dhea) and a selective estrogen receptor ...
Small molecule therapies for pulmonary hypertension
Creighton University
October 12, 2017 - N°20170290819

The present disclosure relates to pirfenidone (5-methyl-1-phenyl-2-(1h)-pyridone) and its derivatives and pharmaceutically acceptable salts thereof, use of these compounds as a medicament, and for the manufacture of a medicament for treating or delaying the onset or development of pulmonary hypertension.
Hypertension Patent Pack
Download 166+ patent application PDFs
Hypertension Patent Applications
Download 166+ Hypertension-related PDFs
For professional research & prior art discovery
inventor
  • 166+ full patent PDF documents of Hypertension-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Therapeutic cd47 antibodies
Tioma Therapeutics, Inc.
October 05, 2017 - N°20170283498

Provided are monoclonal antibodies and antigen-binding fragments thereof that bind to, and inhibit the activity of, cd47, as well as monoclonal antibodies and antigen binding fragments thereof that compete with the former for binding to cd47. Also provided are combinations of any of the foregoing. Such antibody compounds are variously effective in 1) treating tissue ischemia and ischemia-reperfusion injury (iri) in ...
Inhibitors of the renal outer medullary potassium channel
Merck Sharp & Dohme Corp.
October 05, 2017 - N°20170283416

The present invention provides compounds of formula i and the pharmaceutically acceptable salts thereof, which are inhibitors of the romk (kir1. 1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt ...
Use of nitrite salts for the treatment of cardiovascular conditions
Wake Forest University
October 05, 2017 - N°20170281673

It has been surprisingly discovered that administration of nitrite to subjects causes a reduction in blood pressure and an increase in blood flow to tissues. The effect is particularly beneficial, for example, to tissues in regions of low oxygen tension. This discovery provides useful treatments to regulate a subject's blood pressure and blood flow, for example, by the administration of ...
Inhibitors of the renal outer medullary potassium channel
Merck Sharp & Dohme Corp.
September 28, 2017 - N°20170275302

The present invention provides compounds of formula (i) and the pharmaceutically acceptable salts thereof, which are inhibitors of the romk (kir1. 1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt ...
Inhibitors of the renal outer medullary potassium channel
Merck Sharp & Dohme Corp.
September 28, 2017 - N°20170275298

The present invention provides compounds of formula i and the pharmaceutically acceptable salts thereof, which are inhibitors of the romk (kir1. 1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt ...
Inhibitors of the renal outer medullary potassium channel
Merck Sharp & Dohme Corp.
September 28, 2017 - N°20170275292

The present invention provides compounds of formula i: (i) and the pharmaceutically acceptable salts thereof, which are inhibitors of the romk (kir1. 1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive ...
Inhibitors of the renal outer medullary potassium channel
Merck Sharp & Dohme Corp.
September 28, 2017 - N°20170275283

The present invention provides compounds of formula i and the pharmaceutically acceptable salts thereof, which are inhibitors of the romk (kir1. 1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt ...
Hypertension Patent Pack
Download 166+ patent application PDFs
Hypertension Patent Applications
Download 166+ Hypertension-related PDFs
For professional research & prior art discovery
inventor
  • 166+ full patent PDF documents of Hypertension-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Tripeptide compound, preparation method therefor, and application thereof
Northwest University
September 21, 2017 - N°20170267718

Provided are a tripeptide compound, a preparation method therefor, and an application thereof. The structure of the related compound is represented by formula (i). The provided compound has angiotensin converting enzyme inhibiting bioactivity, and the compound and a pharmaceutical composition thereof play a role in preventing and treating hypertension and other cardiocerebral vascular system diseases.
Negative hydrogen ion intellegrnt filtration system for curing cancer, cardiovascular disease, diabetes, hypertension, nephrotic syndrome, ...
Mega Sun Biomedical Corp.
September 21, 2017 - N°20170267563

A negative hydrogen ion intelligent filtration system includes a housing; a filtering mechanism disposed in the housing and comprising a first filter, a second filter connected to the first filter, a third filter connected to second filter, a fourth filter connected to the third filter, a fifth filter connected to the fourth filter, a sixth filter connected to the fifth ...
Enalapril formulations
Silvergate Pharmaceuticals, Inc.
September 21, 2017 - N°20170266159

Provided herein are stable enalapril oral liquid formulations. Also provided herein are methods of using enalapril oral liquid formulations for the treatment of certain diseases including hypertension, heart failure and asymptomatic left ventricular dysfunction.
Renal neuromodulation for treatment of patients
Medtronic Ardian Luxembourg S.a.r.l.
September 21, 2017 - N°20170265937

A method and apparatus for treatment of heart failure, hypertension and renal failure by stimulating the renal nerve. The goal of therapy is to reduce sympathetic activity of the renal nerve. Therapy is accomplished by at least partially blocking the nerve with drug infusion or electrostimulation. Apparatus can be permanently implanted or catheter based.
Methods of inhibiting pathological angiogenesis with doppel-targeting molecules
Pharosgen
September 14, 2017 - N°20170260278

Described herein are doppel-targeting molecules useful for inhibiting pathological angiogenesis and treating diseases and conditions associated with pathological angiogenesis, such as tumors, cancers, atherosclerosis, tuberculosis, asthma, pulmonary arterial hypertension (pah), neoplasms and neoplasm-related conditions, and for detecting doppel expression in a subject. Related compositions and methods also are described.
Sustained timolol maleate delivery from liposomes for glaucoma therapy and occular hypertension
Nanyang Technological University
August 31, 2017 - N°20170246175

Various embodiments relate to the field of liposomal formulations for drug delivery, in particular, liposomal formulations for ocular drug delivery. More specifically, various embodiments relate to sustained timolol maleate delivery from liposomes for glaucoma therapy and ocular hypertension.
Methods for therapeutic renal neuromodulation
Medtronic Ardian Luxembourg S.a.r.l.
August 31, 2017 - N°20170245926

Methods and apparatus are provided for treating hypertension, e. G., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and ...
Therapeutic use of peptide inhibitors of nadph oxidase; aerosolization as a delivery mechanism
University Of Pittsburgh - Of The Commonwealth System Of Higher Education
August 24, 2017 - N°20170240594

A method is provided for treatment of a condition mediated by nox2 in a patient. The method comprises administering to the patient by inhalation a polypeptide as described herein, able to inhibit superoxide production by nox2. Conditions treatable in this manner include, without limitation, one or more of: right ventricular hypertrophy; pulmonary hypertension; acute lung injury; obstructive sleep apnea; ischemia/...
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