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Hypertension

Hypertension-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Pyridinecarboxamide derivatives, preparation method thereof and pharmaceutical uses thereof
Shanghai Hengrui Pharmaceutical Co., Ltd.
November 30, 2017 - N°20170342059

Pyridinecarboxamide derivatives, preparation methods, and a pharmaceutical uses thereof are provided. In particular, pyridinecarboxamide derivatives represented by general formula (i), wherein the substituents of the formula (i) are defined in the specification are provided. Also provided are a preparation method for the pyridinecarboxamide derivatives of formula (i), a pharmaceutical composition containing the pyridinecarboxamide derivatives, and uses of the pyridinecarboxamide derivatives ...
Preservative-free treprostinil formulations and methods and devices for use with same
Steadymed Ltd.
November 30, 2017 - N°20170340647

This invention provides for a unit dosage form of treprostinil at a dosage of between 0. 1 mg/ml and 25 mg/ml in a sterile fluid composition formulated for subcutaneous or intravenous injection, which composition does not comprise an antimicrobial preservative. Selectively activatable patch-pump assemblies comprising a sealed prefilled drug-reservoir containing the unit dosage form is described as are methods for reducing ...
Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid ...
Ardelyx, Inc.
November 30, 2017 - N°20170340623

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (ppar) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment ...
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Anti-acth antibodies and use thereof
Alder Biopharmaceuticals, Inc.
November 23, 2017 - N°20170334987

The present invention is directed to antibodies and fragments thereof having binding specificity for acth. Another embodiment of this invention relates to the antibodies binding fragments thereof described herein, comprising the sequences of the vh, vl and/or cdr polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-acth antibodies and binding fragments thereof conjugated ...
Organic compositions to treat beta-enac-related diseases
Arrowhead Pharmaceuticals, Inc.
November 16, 2017 - N°20170327829

The present disclosure relates to rnai agents useful in methods of treating beta-enac-related diseases such as cystic fibrosis, pseudohypoaldosteronism type 1 (pha1), liddle's syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a rnai agent to beta-enac.
Method of treating hypertension
Rubicon Research Private Limited
November 16, 2017 - N°20170326066

The present invention relates to methods and composition for treatment of hypertension. Particularly the present invention provides a method of treating hypertension comprising orally administering once a day to a human patient in need thereof the compound valsartan in an extended release dosage form, wherein said extended release valsartan dosage form reduces mean systolic and diastolic blood pressure in a ...
Hypertension Patent Pack
Download 166+ patent application PDFs
Hypertension Patent Applications
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inventor
  • 166+ full patent PDF documents of Hypertension-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Composition
Optibiotix Limited
November 09, 2017 - N°20170318851

The present invention relates to compositions for use and formulation as weight management products and in particular fermented dairy foodstuffs. The compositions generally comprise two or more of the following components: a) a microbiome modifying component; b) a satiety modifying component; and c) a metabolic modifying 5 component and at least one of the following: d) streptococcus thermophilus cbs 139100 and lactobacillus ...
Short acting phenylalkylamine calcium channel blockers and uses thereof
Optibiotix Limited
November 02, 2017 - N°20170312243

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated ...
Short acting phenylalkylamine calcium channel blockers and uses thereof
Optibiotix Limited
November 02, 2017 - N°20170312242

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated ...
Short acting phenylalkylamine calcium channel blockers and uses thereof
Optibiotix Limited
November 02, 2017 - N°20170312241

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated ...
Methods for treatment of disease using galvanic vestibular stimulation
The Regents Of The University Of California
October 26, 2017 - N°20170304616

Methods are provided for treating diseases by altering body mass composition in a human subject through application of galvanic vestibular stimulation (gvs) using electrodes placed in electrical contact with the subject's scalp at a location corresponding to each of the subject's left and right vestibular systems. The methods may be used to treat obesity-related diseases such as diabetes, hypertension, type 2 ...
Binding proteins specific for lox1 and uses thereof
Medimmune Limited
October 26, 2017 - N°20170304343

This disclosure provides lox1 (lox1) binding proteins such as anti-lox1 antibodies, and compositions and methods for making these binding proteins. In certain aspects the lox1-binding proteins provided herein, inhibit, or antagonize lox1 activity. In addition, the disclosure provides compositions and methods for diagnosing and treating conditions associated with atherosclerosis, thrombosis, coronary artery disease (cad), ischemia (e. G., myocardial ischemia), ...
An inhalable rapamycin formulation for the treatment of pulmonary hypertension
Lam Therapeutics, Inc.
October 26, 2017 - N°20170304276

The present invention relates to methods and compositions for the treatment and prophylaxis of pulmonary arterial hypertension (pah) in a human subject in need of such treatment, the methods comprising the pulmonary administration to the subject, preferably via inhalation of a composition comprising rapamycin or a prodrug or derivative thereof.
Hypertension Patent Pack
Download 166+ patent application PDFs
Hypertension Patent Applications
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inventor
  • 166+ full patent PDF documents of Hypertension-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Cardiac troponin i detection during pregnancy for cardiovascular disease identification and risk assessment
Lam Therapeutics, Inc.
October 19, 2017 - N°20170299612

The present invention provides systems and methods for determining and reporting the cardiac troponin i (ctni) concentration in a sample from a pregnant woman (in the first, second, or third trimester) by determining whether the sample (ctni) concentration is higher than a 99th percentile ctni concentration from a corresponding first, second, or third trimester uncomplicated pregnancy control group, thereby determining ...
Sphingosine kinase inhibitors
Lam Therapeutics, Inc.
October 19, 2017 - N°20170298032

Sphingosine kinases are enzymes that catalyze the biosynthesis of sphingosine-1-phosphate. The invention provides compounds that are effective for inhibition of sphingosine kinase type 1, sphingosine kinase type 2, or both. Certain compounds are selective for sphingosine kinase type 2 relative to sphingosine kinase type 1. Compounds of the invention can be used in treatment of a range of diseases wherein increasing the level ...
Treprostinil derivatives and compositions and uses thereof
Lam Therapeutics, Inc.
October 19, 2017 - N°20170298001

The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
Rho associated kinase (rock) inhibitors and their use in treating disease
Lam Therapeutics, Inc.
October 19, 2017 - N°20170296617

The present disclosure describes peptide inhibitors of rho-associtated-kinase (rock) and their use in treating disorders including heart failure, the leading cause of combined morbidity and mortality in the united states. An inhibitory polypeptide blocks rock1 activity in the presence of 1 mm atp. The binding epitope on rock1 was mapped using chemical cross-linking to the activation loop, a novel locus identifying ...
Cardiosphere-derived cells (cdcs) as therapeutic agents for pulmonary hypertension
Lam Therapeutics, Inc.
October 19, 2017 - N°20170296591

Described herein are compositions and techniques for treatment of disease and conditions such as pulmonary arterial hypertension (pah). Unlike palliative or preventive measures that do not address the abnormal vasculature causing onset of right ventricular compensation the use of stem cell-based therapy can directly impact the microvascular pathology in pah, thereby reversing the course of the disease.
Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
Lam Therapeutics, Inc.
October 19, 2017 - N°20170296506

The present application provides methods for treating cardiovascular conditions. The methods can include administering a transient receptor potential vanilloid 1 (trpv1) receptor agonist to an epidural space. The methods can be used to treat a variety of conditions such as hypertension, prehypertension, mild hypertension, severe hypertension, refractory hypertension, congestive heart failure and myocardial scarring.
Improved sugar-depleted fruit or vegetable juice and juice-retaining fruit or vegetable derived matter, methods of ...
Lam Therapeutics, Inc.
October 19, 2017 - N°20170296468

The present invention provides a sugar-depleted fruit or vegetable juice product, wherein said juice product is a fruit or vegetable juice or juice-retaining fruit or vegetable derived matter, wherein said juice product contains at least about 5 g/l gluconic acid and said juice product contains any two or three, of (i) at least about 0. 5 g/l ca2+, (iii) at least ...
Mapping sympathetic nerve distribution for renal ablation and catheters for same
Lam Therapeutics, Inc.
October 19, 2017 - N°20170296264

This invention provides methods for mapping and ablating renal nerves to treat disease caused by systemic renal nerve hyperactivity, e. G. Hypertension, heart failure, renal failure and diabetes. Also provided are catheters for performing the mapping and ablating functions.
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