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Hydroxyapatite

Hydroxyapatite-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Bioactive coated gutta-percha as root canal filling matter
Universiti Malaya
September 07, 2017 - N°20170252269

The present invention relates to the deposition of a micro-crystalline hydroxyapatite and tricalcium phosphate coating onto gutta-percha cones, to be used as dental composite for root canal filling. The method proposed for coating involves the surface pretreatment of gutta-percha cones with sodium hydroxide; immersion of gutta-percha cones in simulated body fluid, which contains calcium and phosphate ions; and replacing consumed ...
A method for producing a hap (hydroxyapatite)/boron-doped hap and developing composite tissue scaffolds
Universiti Malaya
August 31, 2017 - N°20170246346

The present invention relates to a method for producing biomimetic hydroxyapatite (hap) and boron-doped hap (b-hap) with the support of microwave and a method for coating tissue scaffolds with hap and/or b-hap.
Method for producing porous calcium deficient hydroxyapatite granules
Bioventus, Llc
July 13, 2017 - N°20170197833

The method is for producing porous calcium deficient hydroxyapatite granules and comprises the following steps: (a) subjecting granules of calcium sulfate anhydrous (csa), calcium sulfate dihydrate (csd) or calcium sulfate hemihydrate (csh) to an incubation in an alkaline aqueous solution having a ph-value of less than 10 and containing po43− ions; whereby the granules of calcium sulfate anhydrous (csa), calcium ...
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Composition and methods for tethering bioactive peptides to metal oxide surfaces
The University Of Akron
July 06, 2017 - N°20170189531

In various aspects, embodiments of the present invention are directed to a series of multivalent dendrons containing a bioactive peptide domain and surface-binding catechol domains. In some embodiments, these multivalent dendrons were obtained through solid phase synthesis and have a strong binding affinity to metal oxide surfaces such as, tio2, zro2, ceo2, and fe3o4, sio2, as well as other ...
Nutrient extraction and recovery device for isolation and separation of target products from animal produced ...
University Of Maryland, Baltimore County
June 22, 2017 - N°20170174577

The present invention provides for nutrient extraction and recovery devices that use the donnan membrane principle (dmp) to cause spontaneous separation of dissolved ions along electrochemical potential gradients, wherein anions and cations such as h2po4−, hpo42−, po43−, mg2+, ca2+, nh4+, and k+ are moved from manure containing waste streams through cation and anion exchange membranes into ...
Polarized hydroxyapatite films and methods of making and using same
University Of Rochester
June 22, 2017 - N°20170173213

Polarized hydroxyapatite films disposed on a substrate. The films have a residual polarization of at least 5 mc/cm2. Also provided are methods of making and using polarized hydroxyapatite. The films can be used as coatings of medical devices, such as, for example, medical implants.
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3-d in vitro model for breast cancer dormancy
New Jersey Institute Of Technology
May 11, 2017 - N°20170131273

Disclosed is a three-dimensional (3-d) in vitro model for studying and subsequently treating cancer dormancy. The model is specifically useful in studying breast cancer and may be used for drug discovery because it maintains the breast cancer cells in a dormant state, unlike conventional two-dimensional (2-d) tissue culture plastic (tcp). Tumor-forming breast cancers cells were seeded on the 3-d model ...
Multiple imaging mode tissue marker
C. R. Bard, Inc.
May 11, 2017 - N°20170128154

An intracorporeal marker for marking a site within living tissue of a host having a body of porous hydroxyapatite whose physical properties permit the body to be distinguished from human soft tissue under visualization using ultrasonic and radiation imaging modalities.
Mineral-enzyme complex for strengthening and whitening tooth enamel, oral hygiene composition, and toothpaste
C. R. Bard, Inc.
May 04, 2017 - N°20170119647

The invention relates to the field of cosmetology, namely to mineral-enzyme complexes for tooth enamel strengthening and whitening, and also to compositions for oral hygiene comprising said complex, in particular, to toothpastes and other compositions. The described mineral-enzyme complex for tooth enamel strengthening and whitening is characterized by the fact that it contains calcium hydroxyapatite and tannase with the following ...
Uv-filters, method of producing the same and their use in compositions, in particular sunscreens
Universidade CatÓlica Portuguesa
May 04, 2017 - N°20170119636

The present disclosure relates to new uv-filters, method of producing the same and their use in compositions in particular, cosmetic/pharmaceutical or textile compositions, namely sunscreens cream or sunscreens textile article, in particular the present disclosure relates to hydroxyapatite based-compound comprising ca9feh(po4)7 and/or α-fe2o3 in hematite form for use in a method for protecting ...
Collagen matrix
Warsaw Orthopedic, Inc.
April 13, 2017 - N°20170100510

Methods for making a biodegradable collagen matrix having increased osteoinductivity and a biodegradable collagen matrix prepared by these methods are provided. In various embodiments, the methods include providing an acidic collagen slurry and mixing it with at least one water soluble and/or hydrophilic bioactive agent under conditions sufficient to cause the collagen slurry to self-assemble into macroscopic collagen fibers ...
Producing calcium phosphate compositions
Clean World Technologies Ltd.
March 30, 2017 - N°20170088424

The disclosure features compositions that include a material featuring three calcium phosphate phases that form one or more integral units of a solid, where a first one of the three phases includes one or more regions formed of hydroxyapatite, a second one of the three phases includes one or more regions formed of β-tricalcium phosphate, a third one ...
Plasma-enriched hydroxyapatite-based filler material and method of filling bone gaps with the same
Metrex Research, Llc
March 23, 2017 - N°20170080122

Plasma-enriched hydroxyapatite-based fillers and methods of filling bone gaps in oral surgery, orthopedic procedures, and cosmetic surgery are disclosed. The fillers contain a substance comprising an anticoagulant antidote, a substance comprising hydroxyapatite, and blood or plasma. The blood may be either autologous or allogeneic. The fillers have a dough-like consistency and can be manipulated easily by a surgeon.
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Particulate hydroxyapatite compositions and methods for preparing the same
Honeywell International Inc.
March 02, 2017 - N°20170056304

A method for preparing a fast-drying particulate hydroxyapatite composition includes the steps of reacting a calcium salt aqueous solution with a phosphate salt aqueous solution to obtain a product solution including hydroxyapatite particles in aqueous suspension and a dissolved byproduct salt; purifying the product solution by removing at least a portion of the dissolved byproduct salt to form a purified ...
Spinal screws and methods of using the same
Spinal Usa, Inc.
February 23, 2017 - N°20170049482

Bone screw assemblies that can include a screw, housing, snap ring, saddle, set screw, and rod are described herein. The bone screw assemblies can allow for polyaxial or uniplanr movement of the screw relative to the housing. A threaded portion of the screw can be coated with a hydroxyapatite (ha) coating. The screw can have a triple lead thread configuration. ...
Apparatus and methods for visual demonstration of dental erosion on simulated dental materials
The Procter & Gamble Company
February 09, 2017 - N°20170039893

Comparative effectiveness of various oral care products such as dentifrices on preventing dental erosion may be demonstrated using simulated enamel a substrate is prepared. A mineral layer to simulate dental enamel is nucleated by solution growth on the substrate surface. Alternatively, the mineral layer may be nucleated on a template comprising a self-assembled monolayer formed on a gold layer deposited ...
Compositions and methods for surface mineralization
University Of Massachusetts
February 02, 2017 - N°20170028103

The invention provides novel compositions and methods of surface mineralization for metallic or ceramic implants and devices and the resulting enhancement of properties and performance in skeletal tissue engineering, orthopedic applications and dental care. The novel approach utilizes zwitterionic brushes (e. G., of poly(sulfobetaine methacrylate) or psbma) covalently grafted on the surface of titanium or its alloy substrates (e. ...
Compositions and methods for the prevention and treatment of metabolic diseases
University Of Massachusetts
February 02, 2017 - N°20170027989

The present invention is a new method and composition that enhance bone repair, formation, maintenance and slowing of bone resorption. The present invention relates to methods and compositions that enhance collagen formation, tendon health and tendon injury healing, bone maintenance and bone injury healing, and the prevention and treatment of metabolic diseases. The present invention is a part of the ...
Ultralong hydroxyapatite nanowire/microwire, method of preparing same, hydroxyapatite paper comprising same and preparation method ...
Shanghai Institute Of Ceramics, Chinese Academy Of Sciences
January 26, 2017 - N°20170022668

The invention relates to an ultralong hydroxyapatite nanowire/microwire, a method of preparing the same, a hydroxyapatite paper comprising the same and a preparation method thereof, and provides an ultralong hydroxyapatite nanowire/microwire having a length of tens to hundreds of micrometers and a diameter of tens to hundreds of nanometers. There is also provided a method of preparing the ...
Powder, method of producing powder, and adsorption apparatus
Hoya Corporation
January 19, 2017 - N°20170014798

The present invention provides that powder is mainly constituted from secondary particles of hydroxyapatite. The secondary particles are obtained by drying a slurry containing primary particles of hydroxyapatite and aggregates thereof and granulating the primary particles and the aggregates. A bulk density of the powder is 0. 65 g/ml or more and a specific surface area of the secondary particles is 70 ...
Separation of bispecific antibodies and bispecific antibody production side products using hydroxyapatite chromatography
Hoffmann-la Roche Inc.
December 29, 2016 - N°20160376304

The present invention is directed to methods comprising the use of hydroxyapatite chromatography to separate a bispecific antibody from a solution that also comprises one or more byproducts specific to bispecific antibody production. Byproducts specific to the production of bispecific antibodies (bispecific antibody specific byproducts, “basb”) include fragments of the bispecific antibody and heavier molecular weight ...
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