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Homozygous patents



      
           
This page is updated frequently with new Homozygous-related patent applications. Subscribe to the Homozygous RSS feed to automatically get the update: related Homozygous RSS feeds. RSS updates for this page: Homozygous RSS RSS


Date/App# patent app List of recent Homozygous-related patents
07/31/14
20140215652
 Nucleotide sequences mediating male fertility and method of using same patent thumbnailNucleotide sequences mediating male fertility and method of using same
Nucleotide sequences mediating male fertility in plants are described, with dna molecule and amino acid sequences set forth. Promoter sequences and their essential regions are also identified.
06/26/14
20140182008
 Pygmy sesame plants for mechanical harvesting patent thumbnailPygmy sesame plants for mechanical harvesting
Pygmy sesame plants homozygous for the py/py recessive pygmy allele and a character selected from non-dehiscence or improved non-dehiscence, and a method for breeding the same, are disclosed.. .
06/05/14
20140157448
 Cichorium spp. male sterile mutants patent thumbnailCichorium spp. male sterile mutants
The present invention relates to leaf chicory (cichorium intybus subsp. Intybus var.
05/29/14
20140147919
 Homozygous and heterozygous idh1 gene-defective cell lines derived from human colorectal cells patent thumbnailHomozygous and heterozygous idh1 gene-defective cell lines derived from human colorectal cells
Idh1 gene-defective cell lines (e.g., idh1r132h heterozygous) have been made from a robust cell line, hct116. The idh1 gene-defective cell lines can be used to determine the effect of idh1r132h on cell biology, tumorigenesis, and cellular metabolic profiles.
05/08/14
20140127747
Regulation of translation of heterologously expressed genes
The present invention pertains to a method of expressing a protein of interest, preferably a heterologous protein, in preferably a plant. In a preferred embodiment said plant is a doubled haploid homozygous transgenic nicotiana tabacum plant silenced for ntp303.
04/24/14
20140115736
 Hybrid seed potato breeding patent thumbnailHybrid seed potato breeding
The present invention relates to diploid, fertile, self-compatible and essentially homozygous potato lines, wherein said lines comprise an agronomically desirable trait such as vigour. The invention further relates to methods for producing such plants and to hybrid seeds obtained by crossing such homozygous potato lines and to potato plants grown from said seed..
04/03/14
20140096278
 Methods and compositions for selecting an improved plant patent thumbnailMethods and compositions for selecting an improved plant
The invention is directed, in an embodiment, to a method for producing a transgenic plant comprising: providing a substantially homozygous plant line suitable for transformation; selecting a subline of the plant line having reduced heterogeneity; transforming plant materials from the subline with a transgenic construct that confers a desired trait to at least one transformed plant; recovering at least one transgenic event from the transformation step; and selecting a transgenic event exhibiting a desirable level of the desired trait using plants of the subline as control. The invention is also directed to a method for producing a plant having a desired trait.
03/20/14
20140082765
 Lolium multiflorum line inducing genome loss patent thumbnailLolium multiflorum line inducing genome loss
Dihaploid homozygous fescue species may be produced by interspecific hybridization of fescue with novel ryegrass, lolium multiflorum, lines, that induce genome loss. Plants that are dihaploid homozygous lolium and amphidiploids are also produced..
03/20/14
20140080718
 Systems and methods for identifying sequence variation associated with genetic diseases patent thumbnailSystems and methods for identifying sequence variation associated with genetic diseases
Systems and method for identifying variants associated with a genetic disease can include obtaining calls for a plurality of individuals for a list of variant positions. The calls can be compared to identify variants that are found in affected individuals and absent in non-affected individuals.
02/27/14
20140057795
 Methods and compositions for correlating genetic markers with prostate cancer risk patent thumbnailMethods and compositions for correlating genetic markers with prostate cancer risk
The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and determining a genotype for the subject at a plurality of biallelic polymorphic loci, wherein each of said plurality has an associated allele and an unassociated allele, wherein the genotype is selected from the group consisting of homozygous for the associated allele, heterozygous, and homozygous for the unassociated allele; and b) calculating a cumulative relative risk (crr) for the subject based on the genotype determined in step (a). A crr of greater than 1.00 identifies a subject as having an increased risk of developing prostate cancer and also can identify a subject who is a candidate for early psa screening, prostate biopsy and/or chemoprevention..
02/13/14
20140045181
Determining percentage of fetal dna in maternal sample
Methods, systems, and apparatus are provided for determining whether a nucleic acid sequence imbalance exists within a biological sample. One or more cutoff values for determining an imbalance of, for example, the ratio of the two sequences (or sets of sequences) are chosen.
12/05/13
20130323731
Determination of the depth coverage of the fetal genome
Systems, methods, and apparatus for determining at least a portion of fetal genome are provided. Dna fragments from a maternal sample (maternal and fetal dna) can be analyzed to identify alleles at certain loci.
10/31/13
20130288993
Method for diagnosis and method of treatment of autism spectrum disorders and intellectual disability
We provide a set of novel mutations in hist3h3, amt, gldc and pex7 genes which we have discovered as causative of some autism spectrum disorders and/or intellectual disability after analysis of families with more than one affected child and with consanguineous parents. Based on some of these mutations, we also provide novel treatment options for autism spectrum disorders and/or intellectual disability wherein the novel mutations have been diagnosed.
10/17/13
20130276154
Bank of stem cells for producing cells for transplantation having hla antigens matching those of transplant recipients, and methods for making and using such a stem cell bank
Methods for producing stem cell banks, preferably human, which optionally may be transgenic, e.g., comprised of homozygous mhc allele cell lines are provided. These cells are produced preferably from parthenogenic, ivf, or same-species or cross-species nuclear transfer embryos or by dedifferentiation of somatic cells by cytoplasm transfer.
09/26/13
20130253844
Identifying a de novo fetal mutation from a maternal biological sample
Systems, methods, and apparatus for determining at least a portion of fetal genome are provided. Dna fragments from a maternal sample (maternal and fetal dna) can be analyzed to identify alleles at certain loci.
09/26/13
20130252330
Homozygous and heterozygous idh1 gene-defective human astrocytoma cell lines
We provide idh1 gene-defective cell lines (e.g., idh1r132h heterozygous and idh1r132h homozygous) derived from dissociated human astrocytoma samples. The cells can be used alone or in combination with each other or other cell types as a tool for determining the impact of idh1r132h on cellular biology, tumorigenesis, and metabolic profiles.
08/15/13
20130212727
Hybrid canola quality brassica juncea
A seed from a first brassica juncea oilseed plant comprising the cytoplasm of moricandia arvensis and characterized as being cytoplasmic male sterile is provided. The seed from the brassica juncea oilseed plant comprises canola quality oil and canola quality meal.
08/01/13
20130198893
Methods of transforming plants
Methods for producing homozygous plants, seeds, and plant cells are provided. Also provided are methods of transformation..
08/01/13
20130198878
Organisms homozygous for targeted modification
Disclosed herein are homozygously modified organisms and methods of making and using these organisms.. .
07/11/13
20130180005
Method to screen plants for genetic elements inducing parthenogenesis in plants
Methods include: utilizing maternal embryo defective recessive mutations which are maintained as a sterile inbred maintenance system, allowing generation of populations that are homozygous for recessive mutant alleles, but transgenically complemented. Methods include utilizing a toxin genes expressed via egg-cell specific promoters, creating a dominant, embryo-less phenotypes, non-transmittable through female gametes.
07/04/13
20130171645
Genetic make-up modifies cancer outcome
A frequent snp a259g (k87e) genotype switch in the mmp8 gene in has been found to modify the clinical behavior of cancers. The modification varies based on the patient's genotype for the snp, and whether homozygous or heterozygous.
05/02/13
20130110407
Determining variants in genome of a heterogeneous sample
After dna fragments are sequenced and mapped to a reference, various hypotheses for the sequences in a variant region can be scored to find which sequence hypotheses are more likely. A hypothesis can include a specific variable fraction for the plurality of alleles that comprise the sequence hypothesis in the region.
04/18/13
20130097736
Lolium multiflorum line inducing genome loss
Dihaploid homozygous fescue species may be produced by interspecific hybridization of fescue with novel ryegrass, lolium multiflorum, lines, that induce genome loss. Plants that are dihaploid homozygous lolium and amphidiploids are also produced..
04/18/13
20130097724
Lolium multiflorum line inducing genome loss
Dihaploid homozygous fescue species may be produced by interspecific hybridization of fescue with novel ryegrass, lolium multiflorus, lines, that induce genome loss. Plants that are dihaploid homozygous lolium and amphidiploids are also produced..
03/28/13
20130081148
Nrip knockout mice and uses thereof
The present invention directs to a transgenic nrip knockout mouse, the genome of which is manipulated to comprise a disruption of a nuclear receptor interaction protein (nrip) gene, wherein the nrip gene is disrupted by deletion of exon 2, the mouse exhibits a phenotype comprising abnormal muscular function. The present invention also directs to a method for making a transgenic nrip knockout mouse whose genome comprises a homozygous disruption of the nrip gene, the mouse exhibits abnormal muscular function..
02/28/13
20130053278
Totipotent, nearly totipotent or pluripotent mammalian cells homozygous or hemizygous for one or more histocompatibility antigens genes
The present invention relates to totipotent, nearly totipotent and pluripotent stem cells that are hemizygous or homozygous for mhc antigens and methods of making and using them. These cells are useful for reduced immunogenicity during transplantation and cell therapy.
02/07/13
20130035404
Integrated analyses of breast and colorectal cancers
Genome-wide analysis of copy number changes in breast and colorectal tumors used approaches that can reliably detect homozygous deletions and amplifications. The number of genes altered by major copy number changes—deletion of all copies or amplification of at least twelve copies per cell—averaged thirteen per tumor.


Popular terms: [SEARCH]

Homozygous topics: Homozygous, Heterozygous, Transgenic, Stem Cells, Transplant, Sequencing, Somatic Cell, Hla Antigen, Hla Antigens, Differentiation, Hemizygous, Astrocytoma, Cytoplasmic Male Sterility, Parthenogenesis, Heterogeneous

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This listing is a sample listing of patent applications related to Homozygous for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Homozygous with additional patents listed. Browse our RSS directory or Search for other possible listings.
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