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Histocompatibility

Histocompatibility-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Novel peptides and combination of peptides for use in immunotherapy against cll and other cancers
Immatics Biotechnologies Gmbh
June 15, 2017 - N°20170165340

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Novel peptides and combination of peptides for use in immunotherapy against various cancers
Immatics Biotechnologies Gmbh
June 15, 2017 - N°20170165339

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Novel peptides and combination of peptides for use in immunotherapy against various cancers
Immatics Biotechnologies Gmbh
June 15, 2017 - N°20170165338

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
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Histocompatibility Patent Applications
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Novel peptides and combination of peptides for use in immunotherapy against pancreatic cancer and other ...
Immatics Biotechnologies Gmbh
June 15, 2017 - N°20170165335

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Genetically modified major histocompatibility complex mice
Regeneron Pharmaceuticals, Inc.
June 15, 2017 - N°20170164590

The invention provides genetically modified non-human animals that express chimeric human/non-human mhc i polypeptide and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various ...
Novel peptides and combination of peptides for use in immunotherapy against various tumors
Immatics Biotechnologies Gmbh
June 08, 2017 - N°20170158750

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
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Histocompatibility Patent Applications
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  • + full patent PDF documents of Histocompatibility-related inventions.
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Novel peptides and combination of peptides for use in immunotherapy against various tumors
Immatics Biotechnologies Gmbh
May 25, 2017 - N°20170145072

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Genetically modified major histocompatibility complex animals
Immatics Biotechnologies Gmbh
May 25, 2017 - N°20170142944

The invention provides genetically modified non-human animals that express chimeric human/non-human mhc i polypeptide and/or human or humanized β2 microglobulin polypeptide, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various ...
Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
Immatics Biotechnologies Gmbh
May 18, 2017 - N°20170136108

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Genetically modified major histocompatibility complex mice
Regeneron Pharmaceuticals, Inc.
May 18, 2017 - N°20170135329

The invention provides genetically modified non-human animals that express a humanized mhc ii protein (humanized mhc ii α and β polypeptides), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same. Methods of using the genetically modified animals to study various aspects ...
Cleavage and exchange of major histocompatibility complex ligands employing azobenzene-containing peptides
Technische Universität München
April 13, 2017 - N°20170101459

In one aspect, the disclosure relates to major histocompatibility complex (mhc) molecules comprising a ligand in the peptide binding groove of the mhc molecule, whereby the ligand comprises an azobenzene (abc), and at least two amino acid residues separated by the azo-group of the abc, and wherein the amino acid residues are positioned to interact with the peptide binding groove ...
Novel peptides and combination of peptides for use in immunotherapy against small cell lung cancer ...
Immatics Biotechnologies Gmbh
April 06, 2017 - N°20170096461

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Medicament for use in a method of inducing or extending a cellular cytotoxic immune response
Bundesrepublik Deutschland Ietzvertreten Durch Das Robert Koch-institut Vertreten Durch Seinen Präsi
March 30, 2017 - N°20170087232

The present invention relates to a medicament for use in a method of extending a cellular cytotoxic immune response against an antigen-comprising protein, the method comprising the step of: i) administering to a patient having t cells activated against an antigen a peptide-loaded major histocompatibility complex class i (mhc-i) presenting cell and an adjuvant which supports a th-1-mediated response, ...
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Histocompatibility Patent Applications
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  • + full patent PDF documents of Histocompatibility-related inventions.
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A medicament for use in a method of inducing or extending a cellular cytotoxic immune ...
Bundesrepublik Deutschland Ietztvertreten Durch Da S Robert Koch-institut Vertreten Durch Seinen Prä
March 23, 2017 - N°20170080067

The present invention relates to a medicament for use in a method of inducing a cellular cytotoxic immune response, the method comprising the steps of: i) administering to a patient a delivery system comprising (a) a molecule binding to a receptor on the surface of a dendritic cell, (b) an antigen-comprising protein bound to molecule of (a) and (c) a ...
Transgenic mice having a human major histocompatibility complex (mhc) phenotype, experimental uses and applications
Institut Pasteur
March 23, 2017 - N°20170079253

The present invention relates to transgenic mice and isolated transgenic mouse cells, the mice and mouse cells comprising a disrupted h2 class i gene, a disrupted h2 class ii gene, a functional hla class i transgene, and a functional hla class ii transgene. In embodiments, the transgenic mouse or mouse cells are deficient for both h2 class i and class ...
Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
Immatics Biotechnologies Gmbh
March 02, 2017 - N°20170056488

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
Immatics Biotechnologies Gmbh
March 02, 2017 - N°20170056487

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
Immatics Biotechnologies Gmbh
March 02, 2017 - N°20170056486

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Method for identifying novel minor histocompatibility antigens
UniversitÉ De MontrÉal
February 16, 2017 - N°20170044213

A novel method for human minor histocompatibility antigen (miha) discovery, novel mihas identified using this method, as well as uses of the novel mihas, are described. One of the features of the novel method is the inclusion of personalized translated transcriptome and/or exome in the database used for peptide identification by mass spectroscopy (ms). Candidate mihas are identified by ...
Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other ...
Immatics Biotechnologies Gmbh
February 09, 2017 - N°20170037111

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other ...
Immatics Biotechnologies Gmbh
February 09, 2017 - N°20170037110

The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated t-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor ...
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