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Hepatitis A

Hepatitis A-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Novel compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and ...
Katholieke Universiteit Leuven K.u. Leuven R & D
June 08, 2017 - N°20170158684

The present invention relates to a novel compound, to a pharmaceutically acceptable salt or optical isomer thereof, to a method for preparing same, and to a pharmaceutical composition for the prevention or treatment of viral diseases containing same as an active ingredient. The novel compound according to the present invention not only has low cytotoxicity but also has excellent antiviral ...
Urea compounds and their use as enzyme inhibitors
Katholieke Universiteit Leuven K.u. Leuven R & D
April 13, 2017 - N°20170101381

Or a pharmaceutically acceptable salt or derivative thereof. The compound may be used in the treatment or prevention of a disorder selected from appetite regulation, obesity, metabolic disorders, cachexia, anorexia, pain, inflammation, neurotoxicity, neurotrauma, stroke, multiple sclerosis, spinal cord injury, parkinson's disease, levodopa-induced dyskinesia, huntington's disease, gilles de la tourette's syndrome, tardive dyskinesia, dystonia, amyotrophic lateral sclerosis, alzheimer's disease, epilepsy, ...
Composition for preventing or treating fatty liver diseases
Lg Life Sciences Ltd.
February 09, 2017 - N°20170035776

The present invention relates to a pharmaceutical composition for preventing or treating fatty liver diseases, containing (tetrahydropyran-4-yl)-[2-phenyl-5-(1,1-dioxo-thiomorpholin-4-yl)methyl-1h-indol-7-yl]amine or a pharmaceutically acceptable salt thereof as active ingredients. (tetrahydropyran-4-yl)-[2-phenyl-5-(1,1-dioxo-thiomorpholin-4-yl)methyl-1h-indol-7-yl]amine or a pharmaceutically acceptable salt thereof, according to the present invention, can effectively ...
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Immunogenic compositions for inhibiting hepatitis d virus
Chrontech Pharma Ab
November 10, 2016 - N°20160324954

Disclosed herein are isolated nucleic acids, compositions of isolated nucleic acids, and compositions of polypeptides that are useful for the generation, enhancement, or improvement of an immune response to a target antigen. Some embodiments of the compositions include nucleic acids encoding hepatitis b core antigen (hbcag) protein in combination with one or more self-cleavage 2a polypeptides and a second antigenic ...
Indanone derivatives, pharmaceutically acceptable salts or optical isomers thereof, preparation method for same, and pharmaceutical ...
Katholieke Universiteit Leuven K.u. Leuven R & D
October 13, 2016 - N°20160297789

Disclosed are novel indanone derivatives, pharmaceutically acceptable salts thereof or enantiomers, a preparation method thereof, and a pharmaceutical composition for the prevention or treatment of viral diseases, comprising the same as an active ingredient. The indanone derivatives have excellent inhibitory activity against picornaviruses including coxsackie-, entero-, echo-, polio-, and rhinoviruses, as well as exhibiting low cytotoxicity, so that they can ...
Compositions and methods for treating non-alcoholic steatohepatitis
Mochida Pharmaceutical Co., Ltd.
July 28, 2016 - N°20160213639

Compositions and methods for the treatment of non-alcoholic steatohepatitis and related disorders are provided herein, for example in women under 50 or pre-menopausal women.
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Treatment of herpes, pseudomonas, staph, and hepatitis
Meritus Corporation
June 02, 2016 - N°20160151436

An improved method (process) is provided to treat herpes, pseudomonas, staphylococcus (staph), and hepatitis and help treat or alleviate cold sores, rashes, skin conditions, or symptoms resulting from herpes, pseudomonas, staph, and hepatitis. The method uses a special medicinal composition which can be self-administered and maintained for a prescribed time. The attractive medicinal composition can comprise a quaternary ammonium salt ...
Antagonists of cb1 receptor
Universite De Bordeaux
May 26, 2016 - N°20160145294

The invention relates to an antagonist of cb1 receptor for use in the treatment of a pathologic condition or disorder selected from the group consisting of bladder and gastrointestinal disorders; inflammatory diseases; cardiovascular diseases; nephropathies; glaucoma; spasticity; cancer; osteoporosis; metabolic disorders; obesity; addiction, dependence, abuse and relapse related disorders; psychiatric and neurological disorders; neurodegenerative disorders; autoimmune hepatitis and encephalitis; pain; ...
Gene signatures of inflammatory disorders that relate to the liver
Institut National De La Recherche Agronomique
March 10, 2016 - N°20160068890

This invention is related to the area of characterization of inflammation in relation with the gut microbiota, in metabolic and autoimmune disorders. In particular, it relates to the identification of gene signatures which can be used as a marker predictive of inflammation associated diseases, such as liver-related metabolic disorders, in particular to the evolution of benign steatosis towards its most ...
Method of producing therapeutic agent
Institut National De La Recherche Agronomique
March 03, 2016 - N°20160058778

The present invention relates to a therapeutic agent, wherein the therapeutic agent is d-boramine. The therapeutic agent is prepared by mixing l-carnitine tartrate, pyridoxal 5′ phosphate and fumaric acid. D-boramine, when administered orally or parenterally in therapeutic quantities, is effective for use in the prevention of cancer that arises from mutations to the brca1 and brca2 genes, i. E., breast ...
Methods of treating liver diseases
Zafgen, Inc.
March 03, 2016 - N°20160058731

The invention provides tricyclic compounds and their use in treating liver disorders, such as non-alcoholic steatohepatitis and related disorders (e. G., fibrosis). The compounds are contemplated to have activity against methionyl aminopeptidase 2.
Selective detection of hepatitis a, b, c, d, or e viruses or combination thereof
The Usa, As Represented By The Secretary, Depart- Ment Of Health And Human Services
February 04, 2016 - N°20160032411

Processes and compositions are provided for the detection of hepatitis viruses in a sample. Particular processes and compositions are provided for the selective detection of hdv. Also provided are processes and compositions for the simultaneous detection of two or more hepatitis viruses that for the first time provide rapid, reliable, and simple detection of any known hepatitis vims in a ...
Novel fatty acids and their use in conjugation to biomolecules
The Usa, As Represented By The Secretary, Depart- Ment Of Health And Human Services
February 04, 2016 - N°20160030585

Wherein r1, r2, r3, r4, ak, n, m and p are defined herein. The invention also relates to a method for manufacturing the conjugate of the invention such as gdf15 conjugate, and its therapeutic uses such as treatment or prevention of metabolic disorders or diseases, type 2 diabetes mellitus, obesity, pancreatitis, dyslipidemia, alcoholic and nonalcoholic fatty liver disease/steatohepatitis and other ...
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Use of heat shock protein inhibitor in preparing pharmaceutical composition for treating hepatitis and hepatoma
National Tsing Hua University
December 24, 2015 - N°20150366892

The present invention is directed to a use of a heat shock protein inhibitor in preparing pharmaceutical composition for treating hepatitis by scavenging hepatitis b virus-infected cells. The heat shock protein inhibitor is selected from a group including ver-155008, pifithrin-μ, and pharmaceutical acceptable salts thereof. The present invention is also directed to a use of a heat shock ...
Novel compound, pharmaceutically acceptable salt or optical isomer thereof, method for preparing the same, and ...
Katholieke Universiteit Leuven K.u.leuven R & D
November 26, 2015 - N°20150336920

The present invention relates to a novel compound, to a pharmaceutically acceptable salt or optical isomer thereof, to a method for preparing same, and to a pharmaceutical composition for the prevention or treatment of viral diseases containing same as an active ingredient. The novel compound according to the present invention not only has low cytotoxicity but also has excellent antiviral ...
Compositions and methods that enhance an immune response
Chrontech Pharma Ab
September 10, 2015 - N°20150252084

Disclosed herein are isolated nucleic acids, compositions of isolated nucleic acids, and compositions of polypeptides that are useful for the generation, enhancement, or improvement of an immune response to a target antigen. Some embodiments of the compositions include hepatitis b core antigen (hbcag) protein and a heterologous protein antigen. In some embodiments, an isolated nucleic acid encoding hepatitis b core ...
Methods of diagnosing liver cancer in a subject and a kit for diagnosing liver cancer
Singapore Health Services Pte Ltd
August 20, 2015 - N°20150232943

Disclosed are methods of diagnosing liver cancer in a subject as well as methods of assessing the risk of a subject having chronic hepatitis and liver cirrhosis of developing liver cancer. Also disclosed are kits for the diagnosis of liver cancer.
Pharmaceutical use of 2-(4-morpholinoaniline)-6-cyclohexyl aminopurine and/or salt thereof for improving liver ...
Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd.
August 13, 2015 - N°20150224106

A method of treating a patient to improve liver functioning includes providing a drug composed of at least one of pharmaceutical 2-(4-morpholinoaniline)-6-cyclohexyl aminopurine and a salt thereof; and administering the drug to the patient in a manner and dosage effective to improve liver functioning. The 2-(4-morpholinoaniline)-6-cyclohexyl aminopurine can inhibit the activated hepatic stellate cells ...
Novel biomarkers for non-alcoholic fatty liver disease, and methods for detecting non-alcoholic fatty liver disease ...
Mcbi, Inc.
August 06, 2015 - N°20150219672

The present invention aims to present methods to detect nonalcoholic fatty liver disease including nonalcoholic steatohepatitis by using a protein or its partial peptide that differs in presence or absence, or in quantity between healthy human subjects and patients with nonalcoholic fatty liver disease or nonalcoholic steatohepatitis or between patients with fatty liver and nonalcoholic steatohepatitis and further aims to ...
Methods and compositions for diagnosis and prognosis of sepsis
Astute Medical, Inc.
June 25, 2015 - N°20150177260

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in sepsis patients and in patients at risk for sepsis. In particular, the invention relates to using assays that detect one or more of wap four-disulfide core domain protein 2, hepatitis a virus cellular receptor 1, interleukin-1 receptor-like 1, and proprotein convertase subtilisin/kexin type 9 as ...
Urea compounds and their use as enzyme inhibitors
Astute Medical, Inc.
June 25, 2015 - N°20150174103

Or a pharmaceutically acceptable salt or derivative thereof. The compound may be used in the treatment or prevention of a disorder selected from appetite regulation, obesity, metabolic disorders, cachexia, anorexia, pain, inflammation, neurotoxicity, neurotrauma, stroke, multiple sclerosis, spinal cord injury, parkinson's disease, levodopa-induced dyskinesia, huntington's disease, gilles de la tourette's syndrome, tardive dyskinesia, dystonia, amyotrophic lateral sclerosis, alzheimer's disease, epilepsy, ...
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