Follow us on Twitter
twitter icon@FreshPatents


Heart patents

      

This page is updated frequently with new Heart-related patent applications.

SALE: 390+ Heart-related patent PDFs



 Biomarkers for risk prediction of mortality patent thumbnailBiomarkers for risk prediction of mortality
The present invention relates to a method for predicting the risk of a subject of rapidly progressing to chronic heart failure and/or of hospitalization due to chronic heart failure and/or death. The method is based on the determination of at least one biomarker selected from the group consisting of a bnp-type peptide, igfbp7 (igf binding protein 7), a cardiac troponin, soluble st2 (sst2), fgf-23 (fibroblast growth factor 23), and growth differentiation factor 15 (gdf-15), in a sample of a subject.
Roche Diagnostics Operations, Inc.


 Biomarker compositions specific to coronary heart disease patients and uses thereof patent thumbnailBiomarker compositions specific to coronary heart disease patients and uses thereof
The present invention relates to a disease-specific metabolite profile, and particularly to a biomarker composition obtained by screening from blood plasma-specific profiles of coronary heart disease subjects. The present invention also relates to a use of the biomarker compositions in risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease, and to a method for risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease.
Bgi Shenzhen


 Flexible smart release tool patent thumbnailFlexible smart release tool
A flexible smart release tool enables a control unit at the surface to individually communicate with release tools that are located downhole. The release tools may be individually addressed using a unique logical identifier.
Halliburton Energy Services, Inc.


 Method and device for recognising the condition of vehicle occupants patent thumbnailMethod and device for recognising the condition of vehicle occupants
The physical and/or mental condition of a vehicle occupant can be recognized on the basis of a bcg (ballistocardiograph) signal, which is obtained by means of a bcg sensor. The bcg sensor is an mem sensor; a cross-correlation of the bcg signal with heartbeat parameters is carried out in an optimum filter, which heartbeat parameters are varied within predefined limits to find a maximum of the cross-correlation function; and probable peaks are located in a cross-correlation function found in this manner and the heart rate is calculated therefrom..
Ford Global Technologies, Llc


 Delivery of cardiac stimulation devices patent thumbnailDelivery of cardiac stimulation devices
Some embodiments of an electrical stimulation system employ wireless electrode assemblies to provide pacing therapy, defibrillation therapy, or other stimulation therapy. In certain embodiments, the wireless electrode assemblies may include a guide wire channel so that each electrode assembly can be advanced over a guide wire instrument through the endocardium.
Boston Scientific Scimed, Inc.


 Blood circulation system patent thumbnailBlood circulation system
An artificial heart and lung apparatus includes a roller pump; a blood removal line; a first blood transfer line; a blood removal rate sensor; a control unit that performs the linked control of the roller pump in correspondence with a blood removal rate; and a blood transfer rate adjustment unit that instructs the roller pump to transfer a blood transfer rate. The blood transfer rate adjustment unit includes an operation amount input unit to which an operation amount from an arbitrary circumferential position can be input, and which outputs a pulse signal according to the input operation amount.
Senko Medical Instrument Mfg. Co., Ltd.


 Trans-catheter ventricular reconstruction structures, methods, and systems for treatment of congestive heart failure and other conditions patent thumbnailTrans-catheter ventricular reconstruction structures, methods, and systems for treatment of congestive heart failure and other conditions
Embodiments described herein include devices, systems, and methods for reducing the distance between two locations in tissue. In one embodiment, an anchor may reside within the right ventricle in engagement with the septum.
Bioventrix, Inc.


 Devices and methods for heart valve repair patent thumbnailDevices and methods for heart valve repair
Devices and methods provide enhanced treatment of a cardiac valve annulus. Methods generally involve contacting an anchor delivery device with the valve annulus and releasing a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus.
Guided Delivery Systems, Inc.


 Convertible annuloplasty ring configured to receive an expandable prosthetic heart valve patent thumbnailConvertible annuloplasty ring configured to receive an expandable prosthetic heart valve
The invention is a cardiac implant, and associated methods therefore, configured to repair and/or replace a native heart valve, and having a support frame configured to be reshaped into an expanded/changed form in order to receive and/or support an expandable prosthetic heart valve therein. The implant may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace/repair a native valve (or other prosthetic heart valve), but to assume a generally non-rigid and/or expanded/expandable form when subjected to an outward force such as that provided by a dilation balloon.
Edwards Lifesciences Corporation


 Methods of rapidly deployable surgical heart valves patent thumbnailMethods of rapidly deployable surgical heart valves
A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures.
Edwards Lifesciences Corporation


Puckering seal for reduced paravalvular leakage

A heart valve assembly includes a heart valve, a self-expandable and collapsible stent, and a sealing member. The stent includes an inflow end and an outflow end and is configured to support the heart valve internally.
St. Jude Medical, Cardiology Division, Inc.

Prosthetic heart valve and method

A system for replacing a deficient native aortic valve includes an implantable prosthetic valve having a self-expandable frame and a valve assembly formed with three valve leaflets. The self-expandable frame includes a plurality of support beams, each support beam having a plurality of preformed bores for allowing the valve assembly to be anchored to the frame at least in part by stitching that extends through the leaflets and through the preformed bores of the support beams.
Edwards Lifesciences Pvt, Inc.

Stents for prosthetic heart valves

A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stem adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.. .
Medtronic, Inc.

Portable measurement of cardiovascular health, system, and method thereof

The disclosure is related to a portable apparatus, and a system for measurement of cardiovascular health, and a method for the same. The portable apparatus is preferably a cuff-less blood pressure device that includes an electrode-based module and a piezoelectric sensor module.
Kentec Inc.

Device group partitions and settlement platform

Device group partitions and a settlement platform are provided. In some embodiments, device group partitions (e.g., partitions of devices based on associated device groups) are provided.
Headwater Research Llc

Shared resource management

Various examples are directed to systems and methods for executing a computing job at a computing node of a distributed computing system. A node controller may receive computing job request data from a system controller.
Red Hat, Inc.

Pregnant abdominal system and associated devices, systems, and methods

Simulated pregnant abdominal systems and associated devices, systems, and methods are provided. The pregnant abdominal systems allow an interactive scenario simulating a routine gestation palpation of a fetal baby, the performance of an external cephalic version as well as the leopold's maneuvers.
Gaumard Scientific Company, Inc.

High definition coloring of heart chambers

A 3-dimensional image is displayed in high resolution colors by generating a 3-dimensional model as a triangular mesh, converting the mesh into a grid of voxels, and assigning attribute values to a portion of the voxels. Laplacian interpolation based on the portion of the voxels is applied for iteratively calculating interpolated attribute values of other voxels.
Biosense Webster (israel) Ltd.

Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders

The invention provides compounds effective as sphingosine-1-phosphate receptor modulators for treatment of cardiopulmonary diseases, such as hypertension (including malignant hypertension), angina, myocardial infarction, cardiac arrhythmias, congestive heart failure, coronary heart disease, atherosclerosis, angina pectoris, dysrhythmias, cardiomyothopy (including hypertropic cardiomyothopy), heart failure, cardiac arrest, bronchitis, asthma, chronic obstructive pulmonary disease, cystic fibrosis, croup, emphysema, pleurisy, pulmonary fibrosis, pneumonia, pulmonary embolus, pulmonary hypertension, mesothelioma, ventricular conduction abnormalities, complete heart block, adult respiratory distress syndrome, sepsis syndrome, idiopathic pulmonary fibrosis, scleroderma, systemic sclerosis, retroperitoneal fibrosis, prevention of keloid formation, or cirrhosis.. .
The Scripps Research Institute

Telescoping catheter delivery system for left heart endocardial device placement

A transseptal catheter delivery system includes an elongate first tubular member and an elongate second tubular member receivable within the first tubular member. The first tubular member includes an adjustable portion adjacent a distal end.
Medtronic, Inc.

Use of ribose for treatment of subjects having congestive heart failure

A method for treating a human subject having congestive heart failure is disclosed herein. An exemplary method includes orally administering a 10 g to 50 g dose of d-ribose daily to a subject having congestive heart failure, wherein the d-ribose is administered in a single dose after fasting, and the administration of d-ribose is continued over a period of time effective to improve cardiac and/or physical function of the subject..
Ribocor, Inc.

Devices, systems, and methods for reshaping a heart valve anulus, including the use of a bridge implant having an adjustable bridge stop

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial adjustability and retrievability years after implant.
Mvrx, Inc.

Systems for placing a coapting member between valvular leaflets

The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve.
Edwards Lifesciences Corporation

Heart valve anchoring device

The present invention relates to an anchoring device (1) designed for anchoring a prosthetic heart valve inside a heart, comprising an extraventricular part (2) designed to be positioned inside an atrium or an artery and a ventricular part (3) designed to be positioned inside a ventricle, wherein the ventricular part comprises a double wall composed of an outer wall (4) and an inner wall (5) spaced apart at the level where the prosthetic heart valve is intended to be inserted, and wherein the anchoring device further comprises a predefined v-shaped groove (8) formed between the extraventricular part (2) and the ventricular part (3). The present invention also relates to an anchoring system (11) for anchoring a prosthetic heart valve inside a heart, comprising said anchoring device (1), a prosthetic heart valve support (12) and a prosthetic heart valve (13) connected to the prosthetic heart valve support (12)..
Tricares Sas

Heart valve prostheses having multiple support arms and methods for percutaneous heart valve replacement

Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom.
Medtronic Vascular, Inc.

Stethoscope system including a sensor array

A stethoscope system may include an array of sensors, which may include pressure sensors. The array may be implemented in a wearable “patch” that is conformable to a patient's body.
Qualcomm Incorporated

Sensor information processing apparatus

A target frequency band to be processed in a detected signal of a heartbeat sensor is controlled according to a detected signal of an inertial sensor.. .
Fujitsu Limited

Sensor information processing apparatus

A detected signal of a heartbeat sensor and a detected signal of an inertial sensor are received by a processor. The processor estimates a heart rate in a case where an exercise intensity obtain from the detected signal of the inertial sensor is equal to or more than a threshold value, based on a relation between the exercise intensity and a heart rate obtained from the detected signal of the heartbeat sensor during a period in which the exercise intensity obtained from the detected signal of the inertial sensor is less than the threshold value..
Fujitsu Limited

System and non-invasively controlling autonomic nerve activity

System and methods for monitoring and/or controlling nerve activity in a subject are provided. In one embodiment, a system includes electrodes configured to be placed proximate to a subject's skin, and a signal detector configured to detect electrical signals using the electrodes.
Indiana University Research & Technology Corporation

Sensor information processing apparatus

A heart rate is estimated based on a detected signal of an inertial sensor, and a timing to control a frequency band to be processed for a detected signal of a heartbeat sensor according to the estimated heart rate is delayed from an estimated timing of the heart rate.. .
Fujitsu Limited

Firmware security interface for field programmable gate arrays

This disclosure provides for implementing a firmware security interface within a field-programmable gate array (fpga) for communicating between secure and non-secure environments executable within the fpga. A security monitor is implemented within the programmable logic of the fpga as a soft core processor and the firmware security interface modifies one or more functions of the security monitor.
Raytheon Company

Treatment of congestive heart failure with electrical stimulation, and associated systems and methods

Systems and methods for treating congestive heart failure with high frequency stimulation are disclosed. A representative method for treating a patient includes applying an electrical signal having a frequency of from about 1 khz to about 100 khz to the patient via a treatment system that includes a signal delivery element in electrical communication with the patient's vagus nerve at a portion of the vagus nerve located at or proximate to the anterior interventricular junction of the patient's heart.
Nevro Corp.

Percutaneous temporary epicardial pacemaker system

This document provides devices and methods for the treatment of heart conditions. For example, this document provides a percutaneous temporary epicardial pacemaker device and system for treating heart arrhythmia..
Mayo Foundation For Medical Education And Research

Methods for anchoring a device at a native heart valve annulus

A method and device for anchoring a prosthetic heart valve or annuloplasty ring to a valve annulus in a heart and a method of implanting same is disclosed. The device can include a prosthetic valve or annuloplasty ring with one or more anchors configured to be threaded or otherwise passed underneath a native leaflet and/or subvalvular tissue to secure the device at the native annulus..
Edwards Lifesciences Corporation

Aortic insufficiency repair device and method

This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In a representative embodiment, a support frame configured to be implanted in a heart valve comprises an annular main body formed by a plurality of angled struts, the main body including a plurality of peaks formed by the intersection of respective adjacent struts.
Edwards Lifesciences Corporation

Transcatheter valve prosthesis

A transcatheter atrio-ventricular valve prosthesis for functional replacement of an atrio-ventricular heart valve in a connection channel, the prosthesis comprising a radially expandable tubular body extending along an axis, and a valve arranged within and attached to the tubular body. The tubular body is provided with an outer circumferential groove which is open to the radial outside of the tubular body, whereby the tubular body is separated by the outer circumferential groove into first and second body sections.
Highlife Sas

Detection of atrial fibrillation causes

This document provides devices and methods for the treatment of heart conditions. For example, this document provides devices and methods for detecting heart rotors such that effectively targeted cardiac fibrillation treatments can be provided..
Mayo Foundation For Medical Education And Research

Connection manager

Systems and methods are described for monitoring, maintaining, and selecting one or more network connections. One or more network connections may be selected based on preferences.
Comcast Cable Communications, Llc

Systems and methods for treating pulmonary hypertension

A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit.
Aria Cv, Inc.

Medical heart valve repair

A surgical instrument for treating atrioventricular valve prolapse of the drained human heart, includes a handle for being held by a surgeon, a shaft extending distally from the handle, the shaft having a lumen open to a shaft distal end, a cannulated needle arranged in the shaft; with a distal end of the needle protruding from the shaft distal end at least in one possible needle position. The needle accommodates a first, distal implant equipped for being anchored in a papillary muscle, and a second, proximal implant shaped to hold on to a leaflet of an atrioventricular valve, the first and second implants each including a chord connector portion for connecting the respective implant to an artificial chord.
Universität Bern

System for loading a collapsible heart valve

An assembly for collapsing a self-expanding prosthetic heart valve includes a compression member, a support member and a constricting member. The compression member has a tapered wall between its first open end and its second open end, the tapered wall defining an open space adapted to receive the valve.
St. Jude Medical, Cardiology Division, Inc.

Suturing ring for prosthetic heart valves

The present subject matter describes a suturing ring for a prosthetic heart valve. The suturing ring has a variable annular thickness reducing continuously from a mid-circumferential plane of the suturing ring towards a top peripheral edge and a bottom peripheral edge of the suturing ring..

Apparatus and heart valve repair

A device for transcatheter gathering of tissue of a heart valve leaflet may include an elongated tube extending in a longitudinal direction and having an open distal end, a tissue securing component disposed at the distal end of the elongated tube, and a capture tool movable in the elongated tube between a retracted position and an extended position. The elongated tube may have an inner surface and a lumen extending therethrough.
St. Jude Medical, Llc

System and mapping medical image of single heart chamber

A system of mapping a cardiac image of single heart chamber and a method thereof are disclosed. In the system and method thereof, one heart chamber (such as a left atrium, a left ventricular, a right atrium, right ventricular or aortic structure) can be selected in a 3d-based cardiac image (such as a ct or mri image), and slices of the selected heart chamber are reconstructed and unwrapped by a 2d mapping visual display manner.
National Yang-ming University

Emergency medical gloves

A pair of gloves for performing cardiopulmonary resuscitation (cpr) is disclosed. The left hand glove comprises a sensor detector in form of heart shape, or the like.

Delivery device for a stented prosthetic heart valve

A delivery device for percutaneously delivering a stented prosthetic heart valve includes a capsule assembly, a handle, and an outer stability shaft. The capsule assembly includes a capsule and a proximal shaft coupled to the capsule.
Medtronic, Inc.

Systems and methods for delivering a medical implant

The present invention relates to apparatus and methods for endovascularly delivering and releasing a prosthesis, e.g., an aortic prosthesis, within and/or across a patient's native heart valve, referred to hereinafter as replacing the patient's heart valve. In some embodiments the delivery system comprises a plurality of first actuatable element adapted to engage a plurality of second elements in a first configuration to capture the implant within the delivery system, and wherein the plurality of first actuatable element are adapted to engage the plurality of second elements in a second configuration and to release the implant from the delivery system..
Boston Scientific Scimed, Inc.

Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications

A prosthetic heart valve is provided with a cuff having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion adapted to bear on the lvot when the valve is implanted in a native aortic valve.
St. Jude Medical, Llc

Artificial valved conduits for cardiac reconstructive procedures and methods for their production

Artificial heart valve structures and methods of their fabrication are disclosed. The heart valve structures may be fabricated from a biocompatible polymer and include one or more heart valve leaflet structures incorporated within a conduit.
University Of Pittsburgh - Of The Commonwealth System Of Higher Education

Prosthetic heart valve cooling

Methods of compressing a stented prosthetic heart valve are disclosed. The method including inserting a stented prosthetic heart valve having a self-expandable stent frame into a container, initiating a cooling element in the container, transferring heat through a thermal conductor to cool an interior of the container, reducing a temperature of the self-expandable stent frame while located within the container to a critical temperature of not greater than 8° c., and compressing an outer diameter of the stented prosthetic heart valve while the stented prosthetic heart valve is at the critical temperature..
Medtronic Vascular, Inc.

Devices, using and monitoring heart valves

heart valves are provided, comprising a heart valve and a plurality of sensors. Briefly stated, heart valves having sensors, as well as related delivery devices are provided with a number of sensors to monitor the integrity and efficaciousness of the device.
Canary Medical Inc.

Quantitative heart monitoring and diagnostics

Described are systems, devices, and methods for deriving quantitative metrics of heart condition and function from one or more electrocardiograms or time-frequency maps derived therefrom. In various embodiments, repolarization indices for the left and right ventricles are determined from the t wave in respective electrocardiograms.
Heart Test Laboratories, Inc.

System and methods for treating mvo

Mvo is treated by introducing injectate into blood vessels affected by mvo at precise flow rates, while blocking retrograde flow, such that the natural pumping of the heart aids in forcing the injectate into the affected microvessels. Monitoring pressure distal of an occlusion balloon is used to determine treatment effectiveness and heart health..
Reflow Therapeutics Ag

Inflatable medical devices

Inflatable medical devices and methods for making and using the same are disclosed. The devices can be medical invasive balloons, such as those used for transcutaneous heart valve implantation, such as balloons used for transcatheter aortic-valve implantation.
Loma Vista Medical, Inc.

Method of repairing a heart valve

A method of repairing the heart valve is described. The method includes securing a first tissue anchor to a first posterior portion of annulus between posterior and anterior commissures; securing a second tissue anchor to a first anterior portion of the annulus between the posterior and anterior commissures; and securing a third tissue anchor to a second anterior portion of annulus between the posterior and anterior commissures.
Hangzhou Dinova Medtech Co., Ltd.

Systems for implanting an endoprosthesis

The invention relates to a catheter for the transvasculur implantation of prosthetic heart valves, in particular comprising self-expanding anchorage supports (10), which allow a minimally invasive implantation of prosthetic heart valves. The aim of the invention is to reduce the risk to the patient during the implantation.
Jenavalve Technology, Inc.

Prosthetic heart valve and method

A prosthetic heart valve comprises a radially crimpable and radially expandable, net-like, annular support frame and a valve assembly disposed therein, the valve assembly comprising a conduit tapering from an inlet towards an outlet thereof. Some embodiments or the support frame comprise a proximal portion and a distal portion, a diameter of the proximal portion smaller than a diameter of the distal portion.
Edwards Lifesciences Pvt, Inc.

Paravalvular leak protection

A prosthetic heart valve includes a collapsible and expandable stent having a proximal end and a distal end, and a collapsible and expandable valve assembly, the valve assembly including a plurality of leaflets connected to at least one of the stent and a cuff. The heart valve further includes a conformable band disposed about the perimeter of the stent near the proximal end for filling gaps between the collapsible prosthetic heart valve and a native valve annulus..
St. Jude Medical, Cardiology Division, Inc.

Collapsible/expandable prosthetic heart valves with native calcified leaflet retention features

A prosthetic heart valve includes an annular frame that is adapted for (1) delivery into a patient's native heart valve annulus in a circumferentially collapsed condition, and (2) circumferential re-expansion when in the annulus, the frame, in an expanded condition. The frame having a longitudinal axis, an inflow end and an outflow end, a first portion of the frame adjacent the inflow end inclining radially outwardly in a direction toward the inflow end, and a second portion of the frame between the first portion and the outflow end bulging radially outwardly, the second portion of the frame being positioned between a first axial distance from the inflow end and a second axial distance from the inflow end.
St. Jude Medical, Llc

Two-stage collapsible/expandable prosthetic heart valves and anchoring systems

A prosthetic heart valve includes a stent having an expanded configuration and a collapsed configuration, the stent in the expanded configuration having a longitudinal axis, an inflow end, an outflow end, a first portion adjacent the inflow end and a second portion adjacent the outflow end. The first portion includes a plurality of collapsible cells each having a perimeter and an open center; and the second portion includes a plurality of struts spaced from one another in an annular direction of the stent, the second portion of the stent being devoid of structure between annularly adjacent ones of the struts, whereby the annularly adjacent ones of the struts are not directly connected to one another.
St. Jude Medical, Llc

Systems and methods for heart valve therapy

Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Some embodiments of prosthetic mitral valves described herein include an anchor portion that couples the prosthetic mitral valve to the anatomy near the native mitral valve, and a valve portion that is mateable with the anchor portion..
Caisson Interventional, Llc

Methods and endovascularly replacing a patient's heart valve

The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid.
Boston Scientific Scimed, Inc.

Paravalvular sealing via extended cuff mechanisms

A prosthetic heart valve 300 may include a collapsible and expandable stent 306 having a proximal end 302, a distal end 304, an annulus section adjacent the proximal end, and a plurality of cells connected to one another in annular rows around the stent, a cuff 312 attached to the stent, and a sealing member 322 attached to the cuff and extending from a proximal end 313 of the cuff to a free edge 323. The sealing member 322 may be movable between an extended condition in which the free edge 323 is located proximally of the proximal end 302 of the stent 306, and an inverted condition in which the free edge is located distally of the proximal end of the stent and a first surface 324 of the sealing member confronts an outward-facing surface of the cuff.
St. Jude Medical, Cardiology Division, Inc.

Improved embolic protection device and method

A catheter device is disclosed comprising; an elongate sheath (503) with a lumen and a distal end for positioning at a heart valve (6), an embolic protection device (200) for temporarily positioning in the aortic arch for deflection of embolic debris from the ascending aorta to the descending aorta, said embolic protection device is connectable to a transluminal delivery unit (130) extending proximally from a connection point (131), and having: a frame with a periphery, a blood permeable unit within said periphery for preventing embolic particles from passing therethrough with a blood flow downstream an aortic valve into side vessels of said aortic arch to the brain of a patient, and at least one tissue apposition sustaining unit (300, 350) extending from said catheter, into said aortic arch, and being attached to said embolic protection device at a sustaining point (502), for application of a stabilization force offset to said connection point at said embolic protection device, such as at said periphery, and for providing said stabilization force towards an inner wall of said aortic arch, away from said heart, and in a direction perpendicular to a longitudinal extension of said periphery, when said catheter device is positioned in said aortic arch, such that tissue apposition of said periphery to an inner wall of said aortic arch is supported by said force for improving stability and peripheral sealing. In addition related methods are disclosed..
Swat Medical Ab

System and reshaping right heart

The present teachings provide devices and methods of reshaping the right heart and reducing tricuspid valve regurgitation. Specifically, one aspect of the present teachings provides an inflatable device to be deployed in the space between the sternum and the right heart.
Mitralign, Inc.

Apparatus and heart valve repair

A device 10 for gathering tissue in a patient includes an elongated catheter 14 and a capture assembly 13 at a distal portion of the catheter. The capture assembly has a closed side 18 and a door 20 rotatable between an open condition and a closed condition.
St. Jude Medical, Llc

System and measuring hemodynamic parameters from the heart valve signal

A system and method for monitoring and diagnosing heart conditions may include capturing and processing a composite heart signal and isolating individual components of such a composite signal. The disclosed techniques of measuring hemodynamic parameters may extract information contained in cardio-pulmonic vibrations.
Aventusoft, Llc

Emotion estimation system, emotion estimation method, and computer-readable recording medium

An emotion estimation system includes a memory; and a processor coupled to the memory, wherein the processor executes a process including, acquiring information on one user's heartbeat intervals measured continuously; classifying user's emotion as any one of at least two types of emotions on the basis of a value indicating a ratio of a value obtained as a result of frequency analysis of the acquired heartbeat interval information to a value indicating a gap between a predicted heartbeat interval calculated on the basis of the acquired heartbeat interval information and an actually obtained heartbeat interval; and performing a different output according to a result of the classifying.. .
Fujitsu Limited

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Multi function smart wristlets

The embodiments disclose a new type of multi-function smart wristlets, in which a variety of electronic, optoelectronic, and thermal sensors are embedded. These sensors will collect data through various signals from both a person and the environment in order to perform many functions to help people improve their health; it also tells people of the environmental conditions in order for them to make the right decision about their outdoor activities.

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

System and extraction of the heart valve signals

A system for monitoring and diagnosing heart conditions includes a sensor array with accelerometers, an electrocardiogram sensor, and a system to capture and process the composite heart signals. The system performs source separation to extract information contained in cardio pulmonic vibrations.
Aventusoft, Llc

System and identification of the heart valve signals

A system for identifying heart valve signals includes a non-invasive sensor unit for capturing electrical signals and composite vibration objects, a memory containing computer instructions, and one or more processors coupled to the memory, where the one or more processors are configured to perform the steps of separating a plurality of individual heart vibration events from the composite vibration objects by using at least one among bin-wise clustering and permutation alignment, or non-negative matrix factorization, or deep belief networks and tagging the plurality of individual heart vibration events using at least one among principal component analysis, gabor filtering, generalized cross correlation, phase transform, smoothed coherent transformation, roth correlation or band filtering.. .
Aventusoft, Llc

System and marking cardiac time intervals from the heart valve signals

A system for marking cardiac time intervals from heart valve signals includes a non-invasive sensor unit for capturing electrical signals and composite vibration objects, a memory containing computer instructions, and one or more processors coupled to the memory. The one or more processors causes the one or more processors to perform operations including separating a plurality of individual heart vibration events into heart valve signals from the composite vibration objects, and marking cardiac time interval from the heart valve signals by detecting individual heartbeats and processing cumulative energy within the individual heartbeat to set a threshold to set a marking point..
Aventusoft, Llc

System and extraction, identification, marking and display of heart valve signals

A system (100) for monitoring and diagnosing heart conditions includes a sensor array (102) with accelerometers, an electrocardiogram sensor, and a system to synchronously capture and process (103, 105, or 106) composite heart signals. The system performs separation, identification and marking (201-205 or 501-509) of the signals, to extract information in cardiac vibrations.
Aventusoft, Llc

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Floormat physiological sensor

A stand-on physiological sensor (e.g. Floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ecg waveforms.
Tosense, Inc.

Systemic delivery of virus vectors encoding urocortin-2 and related genes to treat diabetes-related cardiac dysfunctions and congestive heart failure

In alternative embodiments, provided are methods for treating, ameliorating or protecting (preventing) congestive heart failure (chf) or a diabetes-related cardiac dysfunction, comprising: providing a urocortin 2-encoding and/or a urocortin 3-encoding nucleic acid, transcript or message, or gene, operatively linked to a transcriptional regulatory sequence, optionally contained in an expression vehicle or a vector such as an adeno-associated virus (aav), e.g., an aav8 serotype; and administering to an individual or a patient in need thereof, such as a type 2 diabetic (t2dm), e.g., by iv administration, thereby treating, ameliorating or protecting against (preventing) the t2dm and/or the diabetes-related cardiac dysfunction in the individual or patient.. .
The Regents Of The University Of California

Method and composition for treating heart failure with preserved ejection fraction

A pharmaceutical composition for treatment of persons afflicted of heart failure with preserved ejection fraction (hfpef), diastolic heart failure (dhf) or diastolic dysfunction (df), the composition comprising a therapeutically effective amount of a compound capable of specific binding to the relaxin receptor (rxfp1) present on fibroblasts, fibromyoblasts, endothelial cells, endocardial cells, and cardiomyocytes in the cardiac muscle to increase the heart's stroke volume at lower end-diastolic pressure.. .
Relaxera Pharmazeutische Gesellschaft Mbh & Co. Kg

Artemisinin and its derivatives for use in the treatment of trauma haemorrhage and associated conditions

The present invention relates to the treatment of trauma haemorrhage or trauma haemorrhage-induced organ injury and associated disorders (in particular stoke, burns and brain injury) using the anti-malarial compound artemisinin and its derivatives. The present invention also relates to the treatment of myocardial infarction and coronary heart disease (and associated disorders) using the anti-malarial compound artemisinin and its derivatives.
Queen Mary University Of London

Thrombus management and structural compliance features for prosthetic heart valves

A prosthetic heart valve can include an outer support assembly, an inner valve assembly, which define between them an annular space, and a pocket closure that bounds the annular space to form a pocket in which thrombus can be formed and retained. Alternatively, or additionally, the outer support assembly and the inner valve assembly can be coupled at the ventricle ends of the outer support assembly and the inner valve assembly, with the outer support assembly being relatively more compliant in hoop compression in a central, annulus portion than at the ventricle end, so that the prosthetic valve can seat securely in the annulus while imposing minimal loads on the inner valve assembly that could degrade the performance of the valve leaflets..
Tendyne Holdings, Inc.

Delivery systems and methods of implantation for prosthetic heart valves

A delivery system for delivery of an implantable stented device to a body lumen that includes an elongated member having a distal tip and a proximal end portion, a wire connection member positioned between the distal tip and proximal end portion of the elongated member, and a plurality of capturing wires extending from a distal end of the wire connection member. Each of the capturing wires includes a distal end having a lower portion that is moveable relative to an upper portion between an open position and a closed position, and a slot defined by the upper and lower portions when they are in the closed position..
Medtronic, Inc.

Device and temporary or permanent suspension of an implantable scaffolding containing an orifice for placement of a prosthetic or bio-prosthetic valve

In a surgical method for improving cardiac function, an implantable scaffold or valve support device is inserted inside a patient's heart and attached to the heart in a region adjacent to a natural mitral or other heart valve. The scaffold or valve support device defines an orifice and, after the attaching of the scaffold or valve support device to the heart, or temporary support while native valve leaflets and/or subvalvular structures are captured, a prosthetic or bio-prosthetic valve seated in the orifice, and the native valve may be retracted into the scaffold/replacement assembly to create a gasket for sealing the complex..

Inductive non-contact resistance measurement

Embodiments herein describe a user device that includes a dual purpose coil (or inductor) used when performing inductive sensing and when transferring electrical power to the user device. When performing inductive sensing, the user device couples the coil to a sensing circuit which measures a resistivity of a lossy material inductively coupled to the coil.
Synaptics Incorporated

Central cavity perfusion calculation

A system, method and non-transitory computer readable storage medium for monitoring a perfusion of a patient. The system, method and computer readable storage medium receive an indication of a voltage applied across a chest of the patient via a first electrode, receive a measurement of a current across the chest of the patient, resulting from the applied voltage via a second electrode, generate an impedance-based respiratory rate waveform based on the applied voltage and the measured current, generate a fourier transform of the respiratory rate waveform relative to a heartbeat of the patient, isolate cardiac artifacts in the fourier trans form and generate a perfusion waveform indicating a perfusion of a chest cavity of the patient based on the isolated cardiac artifacts..
Koninklijke Philips N.v.

Artificial lung and artificial heart-lung circuit device

An artificial lung has a gas exchanger portion with an external circulation-type gas exchanging hollow fiber membrane bundle and a heat exchanger portion with a heat exchanging element. Various design parameters of the gas exchanger and heat exchanger portions are configured to obtain a predetermined performance factor.
Terumo Kabushiki Kaisha

Artificial lung and artificial heart-lung circuit device

An artificial lung has a gas exchanger portion with an external circulation-type gas exchanging hollow fiber membrane bundle and a heat exchanger portion with a heat exchanging element. Various design parameters of the gas exchanger and heat exchanger portions are configured to obtain a predetermined performance factor.
Terumo Kabushiki Kaisha

Pulmonary artery implant apparatus and methods of use thereof

The present invention relates to an implantable apparatus and methods of use thereof for treating congestive heart failure. An apparatus of this invention may be anchored by implantation of a section of the apparatus within in a branch pulmonary artery, for example the left pulmonary artery, which then positions and anchors another section, for example a device frame section of the apparatus within the main pulmonary artery.

System for improving cardiac function by sealing a partitioning membrane within a ventricle

Partitioning devices that may be secured and sealed within a heart chamber for separating a patient's heart chamber into a productive portion and a non-productive portion are described herein. The partitioning devices described herein may include a membrane with a plurality of inflatable elements.

Holder and deployment system for surgical heart valves

A holder for a hybrid heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The hybrid heart valve includes a non-expandable, non-compressible prosthetic valve and a self-expandable anchoring stent, thereby enabling attachment to the annulus without sutures.
Edwards Lifesciences Corporation

Endovascular flexible stapling device

The present invention concerns a flexible stapling device (1). More particularly, this invention concerns a flexible endovascular stapling device (1) for an intravascular procedure such as patent foramen ovate closure, which is designed to avoid open heart surgery by permitting the closure of the defect utilizing a stapling means (26) which is positioned by using a flexible shaft/guidewire system..
The Trustees Of Columbia University In The City Of New York

Method and system for measuring flow through a heart valve

A system for presenting multiple parallel slices comprises a display for displaying ultrasound data comprising 3d doppler data over time. A user interface defines a proximal plane and a distal plane within the ultrasound data that are parallel to one another.
General Electric Company

Detecting seizures based on heartbeat data

A method includes receiving heartbeat data of a patient and receiving activity data of the patient. The activity data includes one or more activity values that are related to an activity level of the patient and that are measured independently of the heartbeat data.
Cyberonics, Inc.

Method, device, system and computer programme for filtering an rr series obtained from a cardiac signal with automatic checking of the quality of the rr series

The method is used for filtering an initial rr series of a plurality of (rri) samples which are respectively a function of the time intervals (δti) that separate two successive heartbeats. In order to carry out this filtering, one must automatically detect in the initial rr series if one or more successive (rri) samples are incorrect, and automatically correct in the rr series one or more of the (rri) samples detected as being incorrect by replacing them with one or more reconstructed (rrc) samples so as to obtain an rr series.
Mdoloris Medical Systems

Electronic device and computer-readable recording medium

An electronic device includes a storage that stores therein pulse rate ranges using a resting heart rate of a user as a reference to be associated with exercise amounts, respectively, and a processor. The processor executes a process including: acquiring a first sensor value and a second sensor value from a first sensor and a second sensor that are sensors worn on a body of the user, respectively, the first sensor detecting pulses and the second sensor detecting an acceleration; calculating a plurality of pulse rate candidates based on the acquired first sensor value; calculating an exercise amount of the user based on the acquired second sensor value; and specifying a pulse rate range stored in the storage to be associated with the calculated exercise amount and deciding a pulse rate candidate included in the specified pulse rate range as a pulse rate of the user..
Murata Manufacturing Co., Ltd.

Identity recognition with living signatures from multiple devices

Identity recognition is achieved using user's living signatures, such as a heartbeat signal, from multiple devices. A user requests identity recognition for using a first registered device, such as a mobile device.
International Business Machines Corporation

Rfid based event sensor

The disclosure is directed to a sensor in which the sensing capability is made possible without need for having an independent power source of the sensor. The sensor can include a standard rfid tag, a reed switch, and an antenna.
Facebook, Inc.

Method for predicting congenital heart defect

Particular aspects of the invention confirm significant differences in methylation of cytosine bases in many loci throughout the genome in cases of congenital heart defect (chd) compared to normal cases without chd. Additional aspects provide novel methods for the prediction of congenital heart defects that can be applied to embryos, fetuses, newborns and different stages of postnatal life including childhood and any time in later postnatal life, is disclosed.
Bioscreening And Diagnostics Llc

Ventricular assist device for intraventricular placement

A ventricular assist device includes a pump such as an axial flow pump, an outflow cannula connected to the outlet of the pump, and an anchor element. The anchor element is physically connected to the pump, as by an elongated element.
Heartware, Inc.

Devices, systems, and methods for reshaping a heart valve annulus

Anchors for securing an implant within a body organ and/or reshaping a body organ are provided herein. Anchors are configured for deployment in a body lumen or vasculature of the patient that are curved or conformable to accommodate anatomy of the patient.
Mvrx, Inc.

Devices and methods for transcatheter valve loading and implantation

The present disclosure relates to numerous devices and methods for transcatheter stented prosthetic heart valve loading and delivery. Such devices and methods reduce suture tangling and also provide the ability to adjust the stented prosthetic heart valve expansion and contraction prior to the final release of the stented prosthetic heart valve from the delivery device..
Medtronic Vascular, Inc.

Devices and methods for transcatheter valve loading and implantation

The present disclosure relates to numerous delivery devices and methods for transcatheter prosthetic heart valve loading, deployment and delivery utilizing at least one suture. Disclosed delivery devices utilize improved suture routing methods and configurations that reduce suture tangling and also provide the ability to adjust the prosthetic heart valve expansion and contraction prior to the final release of the prosthetic heart valve from the delivery device..
Medtronic Vascular, Inc.

Delivery system having retractable wires as a coupling mechanism and a deployment mechanism for a self-expanding prosthesis

A delivery system for transcatheter implantation of a heart valve prosthesis. The delivery system includes an outer sheath component defining a lumen therethrough, an elongate tube having at least two flat wires longitudinally extending from a distal end thereof, and self-expanding first and second frames disposed in series within a distal portion of the outer sheath component and held in a compressed delivery configuration therein.
Medtronic, Inc.

Valve delivery device with a piezochromatic feedback indicator and methods of use

heart valve delivery systems and methods for providing a clinician with feedback during a stented prosthetic heart valve delivery procedure. Feedback is provided using piezochromatic indicators incorporated into elements of the delivery device, such as the handle assembly, shaft assembly and capsule to indicate when detrimental forces, or forces nearing those that are detrimental, are being applied to the delivery device during the prosthetic heart valve loading, delivery or deployment procedure.
Medtronic Vascular, Inc.

Delivery system having retractable wires as a coupling mechanism and a deployment mechanism for a self-expanding prosthesis

A delivery system for transcatheter implantation of a heart valve prosthesis. The delivery system includes an outer sheath component defining a lumen therethrough, an elongate tube having at least two flat wires longitudinally extending from a distal end thereof, and self-expanding first and second frames disposed in series within a distal portion of the outer sheath component and held in a compressed delivery configuration therein.
Medtronic, Inc.

Heart valve prosthesis for percutaneous replacement of a tricuspid valve, and system comprising a heart valve prosthesis of said type

The invention relates to a heart valve prosthesis for percutaneous replacement of a tricuspid valve including a stent-type support structure and a biological heart valve; the stent-type support structure can autonomously expand from a radially compressed state into a radially expanded state and includes a fluid-tight cover which extends like a tube over at least some portions of the support structure; the heart valve is arranged in a lateral opening in the support structure. Embodiments further relate to a system including a heart valve prosthesis of said type..

Transcatheter heart valve replacement systems, heart valve prostheses, and methods for percutaneous heart valve replacement

Prosthetic heart valve devices, heart valve replacement systems and associated methods for percutaneous heart valve replacement are disclosed herein. A transcatheter heart valve prosthesis configured in accordance herewith includes an expandable frame having a plurality of commissure posts extending therefrom, a radially expandable inflow member attached to the plurality of commissure posts, and a locking mechanism operably coupled to a wire.
Medtronic, Inc.

Systems for replacing a native heart valve and aorta with a prosthetic heart valve and conduit

A medical device includes an expandable conduit, a prosthetic heart valve and a delivery device, including a balloon catheter. The expandable conduit may include one or more inner or outer sleeves supported by a frame or stent.
Edwards Lifesciences Corporation

Bowed runners for paravalvular leak protection

A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, the stent being formed of a plurality of struts forming cells. A valve assembly is disposed within the stent, the valve assembly including a plurality of leaflets and a cuff.
St. Jude Medical, Cardiology Division, Inc.

Heart failure evaluation method and diagnosis device

Provided are a means to detect a plurality of dynamics, a processing unit that calculates a temporal change in the detected dynamics, and an evaluation device that determines exacerbation of clinical conditions in heart failure of a patient based on the calculated change in the patient's dynamics over time. The present invention makes it possible to detect, early and with high accuracy, that the onset of acute heart failure is imminent..
Teijin Pharma Limited

Treating dysfunctional cardiac tissue

Medical devices, systems, and methods reduce the distance between two points in tissue, often for treatment of congestive heart failure and often in a minimally invasive manner. An anchor is inserted along an insertion path through a first wall of the heart.
Bioventrix, Inc.

Devices, systems, and methods for reshaping a heart valve annulus

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability.
Mvrx, Inc.

An annuloplasty system

An annuloplasty device for repairing a heart valve comprises a first and a second support member that overlap each other and form a scissor linkage. The first and second support members are configured to pinch leaflets of the heart valve..
Medtentia International Ltd Oy

Suture deployment of prosthetic heart valve

A delivery apparatus for a prosthetic implant can include an elongate first shaft, a first suture guide coupled to the first shaft, an elongate second shaft, and a second suture guide coupled to the second shaft. The first shaft can extend coaxially through the second shaft and the second suture guide, the first suture guide can be disposed distal to the second suture guide, and the first suture guide and the second suture guide can be configured to be axially movable relative to each other..
Edwards Lifesciences Corporation

Catheter system for introducing an expandable stent into the body of a patient

This disclosure relates to a catheter system for introducing a heart valve stent into the body of a patient. The catheter system includes a catheter tip having a seat portion for accommodating the stent in its collapsed state and a stent holder for releasably fixing the stent, wherein the seat portion is constituted by a first sleeve and a second sleeve, said sleeves being moveable relative to each other and relative to the stent holder, and a catheter shaft for connecting the catheter tip to a handle..
Jenavalve Technology, Inc.

Curved fiber arrangement for prosthetic heart valves

A leaflet including fibers oriented at an angle relative to at least one free edge of the leaflet. A leaflet including mechanisms for increasing coaptation height, preventing billowing, and reducing stress in critical regions of the leaflet.
Children's Medical Center Corporation

Signal detection device and signal detection method

A signal detection device includes a measurer, an arithmetic operation unit, and signal period detector, and detects information such as a cardiac cycle with high accuracy by causing resonance of only a signal such as a heartbeat, the signal having strong pulse characteristics. The measurer measures a signal.
Panasonic Intellectual Property Management Co., Ltd.

Method and system for monitoring stress conditions

A computer-implemented method of assessing a stress condition of a subject (106) includes receiving (302), as input, a heartbeat record (200) of the subject. The heartbeat record comprises a sequence of heartbeat data samples obtained over a time span which includes a pre-sleep period (208), a sleep period (209) having a sleep onset time (224) and a sleep conclusion time (226), and a post-sleep period (210).
Medibio Limited

Metabolomic prediction of congenital heart defect during pregnancy, newborn and pediatric stages

Particular aspects of the invention are methods for assaying metabolite levels in samples from a patient during pregnancy using nuclear magnetic resonance and direct flow injection mass spectrometry. In various methods, the assayed metabolites may be acylcarnitine or one or more of c3-oh (hydroxypropionylcarnitine), c5-oh (c3dc), c10, c5:1-dc (glutaconylcarnitine), c14:1-oh (hydroxytetradecenoylcarnitine) and c14:2-oh.
King's College Hospital Nhs Foundation Trust

Disposable heart monitoring system, apparatus and method

A disposable, heart monitoring device is disclosed. The device comprises a disposable, wearable membrane comprising an adhesive surface and electrodes disposed within or on the membrane.

Method of treating dyspnea associated with acute heart failure

The disclosure pertains to methods of reducing decompensation through acute intervention including in subjects afflicted with acute decompensated heart failure. Particularly, the disclosure provides methods for treating acute cardiac decompensation by administering a pharmaceutically effective amount of relaxin..

Adaptively positioned mitral valve closure plate blocker for repairing mitral regurgitation

An adaptively positioned mitral valve closure plate blocker for repairing mitral regurgitation, comprising a suture and shaping ring (4.1) sutured on a mitral ring (2.1) and a closure plate (4.2); the closing plate (4.2) comprises a tongue-shaped plate and a strut (4.3) located at the top of the tongue-shaped plate and connected to the suture and shaping ring; the closing plate (4.2) can be connected to the suture and shaping ring (4.1), being capable of flapping back and forth and twisting left and right. The suture and shaping ring is sutured on the valve ring (2.1) of the mitral valve (2) of a patient in a thoracotomy and open heart surgery, thus shaping the disease expanded mitral ring (2.1), and supporting the closing plate (4.2); when a heart contracts and valve leaflets close, the closing plate (4.2) flaps and twists depending on the position of a regurgitation opening at the free edge of the valve leaflets to realize adaptive positioning of the closing plate (4.2), so that the closing plate (4.2) is at the free edge when two valve leaflets are closed, covering the regurgitation opening, and is tightly attached to the free edge of the valve leaflets, reducing or avoiding regurgitation of the mitral valve (2)..
Jiangsu University

Device for cutting off and removing calcified tissue from a heart valve

A device for cutting off and removing calcified tissue from a heart valve, including a tubular body suitable for being inserted by way of a minimally invasive or endoscopic channel in relation to a previously inserted guide wire suitable for passing through the flaps of the valve above the portion where the calcified tissue is to be removed. One of the ends of the body, viewed at the flaps, has a profiled tip made of flexible material and arrangements for the lateral projection of a cutting member for cutting the tissue.

Ablation creating elongate continuous lesions enclosing multiple vessel entries

A method of creating a lesion in cardiac tissue where the method includes deploying a distal treatment section of an ablation catheter into a heart chamber and manipulating the distal treatment section against the cardiac tissue and into a curved shape that encloses a plurality of vessel entries in the heart chamber. The method further includes commencing a first application of ablation energy from the distal treatment section to the cardiac tissue and halting the first application of ablation energy to the cardiac tissue.
Adagio Medical, Inc.

Biometric information sensor

A biometric information sensor includes a flexible substrate, an adhesive, a heartbeat signal detector, an electrocardiographic signal detector, a pulse wave detector, and a signal processor. The signal processor calculates an electrocardiographic peak estimated value resulting from estimating the wave of an electrocardiographic signal detected by the electrocardiographic signal detector from a heartbeat signal detected by the heartbeat signal detector based on the heartbeat signal and the electrocardiographic signal.
Murata Manufacturing Co., Ltd.

Devices and methods for reducing intrathoracic pressure

Devices and methods are provided to treat acute and chronic heart failure by using one or more implantable or non-implantable sensors along with phrenic nerve stimulation to reduce intrathoracic pressure and thereby reduce pulmonary artery, atrial, and ventricular pressures leading to reduced complications and hospitalization.. .

Methods for improving muscle and heart function

The present invention encompasses combinations comprising a plurality of amino acids, formulations thereof for use in humans and animals, as well as methods for increasing muscle protein synthesis, muscle strength, and/or muscle function in a subject with chronic heart failure, cardiac cachexia or a combination thereof.. .

Mitral bileaflet valve

A heart valve assembly has a leaflet support structure and a leaflet assembly. The leaflet support structure has a wire frame that supports the leaflet assembly.

Transcatheter valve stent anchors

A stent for use in a prosthetic heart valve has a plurality of expandable and collapsible closed cells, a portion of which form an annulus section adapted for placement within the annulus of the native heart valve. Anchor features of the stent residing within at least some closed cells are adapted to engage tissue of the heart, including native valve leaflets, the sinotubular junction, or another implanted device when the prosthetic valve is implanted in the heart.

Percutaneous heart valve, system, and method

Devices, systems, and methods are provided to treat diseased cardiac valves. The device includes a percutaneous heart valve having an expandable valve frame including valve frame members, a valve leaflet coupled to the valve frame, and an expandable stent anchoring frame coupled to the valve frame including stent frame members defining a first portion and a second portion having greater flexibility than the first portion, where the first portion and the valve frame define a length, and where the stent frame members and the valve frame members along the length provide a contiguous surface over which a delivery device can repeatedly slide over the length in its entirety in two longitudinal directions when the first portion and the valve frame are in a partially expanded state during delivery from the delivery device..

Prosthetic heart valve devices and associated systems and methods

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve.

High durability heart valve

An improved heart bioprosthetic device having a metal frame wireform or stent having an outer external surface. The metal frame has a bond layer coating at least a portion of the external surface and a coating layer disposed on at least a portion of the bond layer.

Leaflet abrasion mitigation

A prosthetic heart valve includes a stent extending in a longitudinal direction and having a plurality of commissure features. A valve assembly is secured to the stent, the valve assembly including a cuff and a plurality of leaflets.

Devices and methods for reducing cardiac valve regurgitation

heart valve regurgitation is reduced by sizing a coapting element to provide a gap between the coapting element and a heart valve when the heart is in a diastolic phase. The size of the coapting element is also selected such that the heart valve seals against the coapting element when the heart is in the systolic phase.

Delivery a medical device

A delivery apparatus for delivering a medical device to a heart defect by a catheter includes a second wire section having a first end securely connected to a first wire section. A connecting member is mounted to a second end of the second wire section and is connected to the medical device.

System and determining poor sensor contact in a multi-sensor device

A system and method are provided for determining sensor contact in a multi-sensor device. The method measures a series of photoplethysmography (ppg) heart beat signals, while simultaneously measuring a series of electrocardiogram (ecg) heart beat signals.

Sound channel configuration method and apparatus and earphone device

Embodiments of the present application provide a sound channel configuration method and apparatus and an earphone device. The method includes: obtaining heartbeat transmission signals at one earpiece and a reference position of a human body; and performing sound channel configuration on a signal of the earpiece at least according to the heartbeat transmission signals at the earpiece and the reference position.
Beijing Zhigu Rui Tub Tech Co., Ltd.

Signal continuity assessment using embedded watermarks

Methods, apparatus, and systems use embedded watermarks to determine whether the segments of a multimedia content has been rearranged. The embedded watermarks are recovered from the content and one or more attributes associated with the recovered watermarks are identified.
Verance Corporation

System for monitoring a to-be-monitored unit of a rack

A system includes a bus, multiple bmcs, and a control unit. Each bmc generates heartbeat signals and acquire operation data associated with a to-be-monitored unit once being initiated, and operates in one of a master mode and a slave mode according to a corresponding decision signal.
Mitac Computing Technology Corporation

Treatment of congestive heart failure and other cardiac dysfunction using a gdf15 modulator

The invention provides methods and compositions of treating a subject having a cardiac-related disorder such as congestive or chronic heart failure (chf), cardiac hypertrophy, cardiac hypotrophy, and other cardiac myopathies/dystrophies. The methods comprise administering an effective amount of a composition that modulates, for example, reduces or inhibits, gdf 15 activity in the subject..
Aveo Pharmaceuticals, Inc.

Wireless diagnostic system for indirect flow measurement in artificial heart pumps

Systems, apparatuses, and methods are disclosed for optimizing management of one or more implanted artificial heart pumps. An example method includes wirelessly retrieving, via one or more portable diagnostic devices, data regarding the one or more implanted artificial heart pumps.

Implantable device and delivery system for reshaping a heart valve annulus

Systems, devices and methods related to various heart valve implants and for delivery of those heart valve implants are described. The implants may be used to re-size a native valve annulus or to replace a native heart valve.
Millipede, Inc.

Mitral valve treatment techniques

A method for treating a heart valve of a patient includes inserting into a heart and in contact with a valve surface, an implant including an elongate element and a locking mechanism coupled to the elongate element. The locking mechanism has a resting position that provides a locked state preventing movement of the elongate element with respect to the locking mechanism.
Valtech Cardio Ltd.

Safety systems for expansion of prosthetic heart valves

Methods of quickly and easily implanting a quick-connect heart valve prosthesis during a surgical procedure are provided. The heart valve may include a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures.
Edwards Lifesciences Corporation

Leaflet-cuff attachments for prosthetic heart valve

A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition, the stent having a proximal end, a distal end and a plurality of commissure features. The heart valve further includes a valve assembly secured to the stent, the valve assembly including a cuff and a plurality of leaflets, each of the leaflets having a free edge having a first end and a second end, and a second edge secured to the cuff, the second edge having a first end, a second end, a first folded portion adjacent the first end, a second folded portion adjacent the second end, and an unfolded portion between the first and second folded portions.
St. Jude Medical, Cardiology Division, Inc.

Systems and methods for helically advancing suture in tissue

Systems and methods for providing transapical access to a heart chamber for performing an intra cardiac procedure are described. The systems include a helical needle driver and a dilator.
Vasostitch, Inc.

Wearable device which diagnoses personal cardiac health condition by monitoring and analyzing heartbeat and the method thereof

A wearable device which diagnoses personal cardiac health condition by monitoring and analyzing heartbeat includes a motion sensor detecting whether the user is in a motion state; a heart rhythm sensor detecting the user's signal of heartbeat interval; a memory storing algorithm program and database for data process, comparison, and analysis; a microprocessor calculating, filtering and judging the signal of heartbeat interval; and a feedback module displaying or alarming a judgment result, wherein the wearable device continuously detects the user's motion state and heartbeat condition, and detects heart rhythm when the user is not in the motion state to further judge the user's cardiac health condition, such as atrial fibrillation.. .
Acme Portable Machines, Inc.

Long connection sharing multi-businesses, system and device, terminal

The present disclosure discloses a long connection sharing method for multi-businesses. The method includes the following steps: a client of the long connection establishes a channel, and obtains heartbeat time; the server of the long connection configures an unique business id for each business, and sends the business id to the client of the long connection; the client of the long connection transmits the business id to a business client, and then the business client reports the business id to a business server corresponding to the business client; after receiving business information, the server of the long connection sends the business information to the client of the long connection through the channel; and the client of the long connection pushes the business information to the business client.
Shenzhen Skyworth-rgb Electronic Co., Ltd.

Implantable heart treatment systems, devices, and methods

Treatment of cardiac tissue via an implantable heart treatment device is described. A device embodiment includes, but is not limited to, a substrate configured for implantation within a body; an electromagnetic signal generator coupled to the substrate and configured to generate one or more electric signals configured to stimulate one or more tissues of a heart within the body; and an energy-carrier molecule delivery device coupled to the substrate and configured to supply one or more non-oxygen cellular energy sources to one or more tissues of the heart within the body..
Elwha Llc

Implantable heart treatment systems, devices, and methods

Treatment of cardiac tissue via an implantable heart treatment device is described. A device embodiment includes, but is not limited to, a substrate; an electromagnetic signal generator configured to generate one or more electric signals configured to stimulate one or more tissues of a heart; a metabolic molecule supply device configured to supply one or more metabolic molecules to one or more tissues of the heart; and control circuitry operably coupled to the electromagnetic signal generator and the metabolic molecule supply device, the control circuitry configured to generate one or more control signals according to at least a first control protocol and a second control protocol, dependent upon a status of a ventricular fibrillation event of the heart..
Elwha Llc

Implantable heart treatment systems, devices, and methods

Treatment of cardiac tissue via an implantable heart treatment device is described. A device embodiment includes, but is not limited to, a substrate configured for implantation within a body; an electromagnetic signal generator coupled to the substrate and configured to generate one or more electric signals configured to stimulate one or more tissues of a heart; and an oxygenator coupled to the substrate and configured to supply one or more oxygenated molecules to one or more tissues of the heart, the oxygenator including a blood inlet portion, a blood outlet portion, and an oxygen exchange portion positioned between the blood inlet portion and the blood outlet portion, the oxygen exchange portion including a high surface area oxygen exchanger configured to transfer one or more oxygenated molecules from the high surface area oxygen exchanger to blood passing from the blood inlet portion to the blood outlet portion..
Elwha Llc

Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue.
Twelve, Inc.

Prosthetic heart valve and delivering the same

A prosthetic heart valve includes a self-expanding wire frame body, a valve disposed in the body, a leaflet clip coupled to the body, and a control element operably coupled to the leaflet clip. The body has a proximal end and a distal end.
Tendyne Holdings, Inc.

Implant delivery capsule

Disclosed herein are embodiments of delivery capsules for delivering prosthetic implants around the relatively tight bends of a catheter. In particular, disclosed herein are delivery capsules including a tubular layer for holding the heart valve, a frame enclosing the tubular layer and an elongate element coupled to the frame for allowing the tubular layer and frame to expand.
Edwards Lifesciences Corporation

Prosthetic heart valve devices and associated systems and methods

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an expandable support having an outer surface and configured for placement between leaflets of the native valve.
Twelve, Inc.

Kidney capsule leaflet material

A prosthetic heart valve provided herein can include a kidney capsule tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member.
Boston Scientific Scimed, Inc.

A process of manufacturing a heart valve made of a polymeric material and the heart valve thereby obtained

A process for the manufacture of a heart valve of polymer material which provides for the deposition of a polymer solution comprising a copolymer which is preferably a copolymer of poly(carbonato-urethane) fluoridate (f-pcu) and intracatenary polydimethylsiloxane (pdms), a pdms with a functional group outside the chain and a solvent onto a mould using a spray technique associated with phase inversion.. .
Humanitas Mirasole S.p.a.

Transcatheter heart valve for replacing natural mitral valve

Embodiments of prosthetic valves for implantation within a native mitral valve are provided. A prosthetic valve may comprise a radially compressible main body and a one-way valve portion.
Edwards Lifesciences Corporation

Actively controllable stent, stent graft, heart valve and controlling same

A delivery apparatus can include a handle portion and at least one rotatable drive shaft. The handle portion can have an actuation mechanism with a motor.
Edwards Lifesciences Cardiaq Llc

Method and system for monitoring the autonomic nervous system of a subject

Method and system for monitoring the autonomic nervous system (ans) of a subject, comprising acquiring at least one physiological signal having w heartbeats, generating data which is a function of the variability of the heart rate on the w heartbeats, with the hrv having w−1 rr intervals separating two consecutive heartbeats detected respectively at the moments tk−1 and tk, each rr interval having a duration of value aκ=tκ−tκ−1 with k=(x−w+2) . .
Societe Codesna

System and improved cardiac rhythm classification from the time between heart beat intervals using non-linear dynamics

A system for classifying cardiac rhythms is disclosed. The system includes one or more processors, one or more computer-readable tangible storage devices, and program instructions stored on at least one of the one or more storage devices for execution by at least one of the one or more processors.
University Of Virginia Patent Foundation

Navigation features for electrocardiograph device user interface

An electrocardiograph device and methods of navigating displays of such a device are disclosed. In one example, an electrocardiograph device includes a display, a plurality of electrocardiograph signal leads, and a programmable circuit.
Welch Allyn, Inc.

System and soft failovers for proxy servers

A packet broker that performs a health-status check of a proxy server while the proxy server processes one or more proxy connections. The packet broker may attempt to exchange a heartbeat signal with the proxy server, and if unsuccessful, the proxy server is assumed to be failing.
Verint Systems Ltd.

Methods and apparatus to prevent illicit proxy communications from affecting a monitoring result

Methods, apparatus, systems and articles of manufacture to prevent illicit proxy communications from affecting a monitoring result are disclosed. An example method includes accessing a log of communications from a proxy.
The Nielsen Company (us), Llc

Devices, methods and systems for establishing supplemental blood flow in the circulatory system

Devices, systems and methods for establishing a blood flow conduit between a chamber in a heart of a patient and a remote location. A blood inflow cannula having an outer surface and proximal and distal end portions.
Circulite, Inc.

Method for reducing paravalvular leaks with decellularized tissue

A method for preparing tissue, in particular pericardial tissue, in particular for use as a sealing means for a heart valve prosthesis for paravalvular leaks, characterised in that the tissue, in particular pericardial tissue, is decellularized (4), subjected to a cross-linking (6) with a glutaraldehyde-containing solution, and subjected to a shape- and a structure-stabilising step (7, 8, 9). The invention also relates to a heart valve prosthesis..
Biotronik Ag

Replacement prosthetic heart valves

A two-stage or component-based valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve comprises a support structure that is deployed at a treatment site.
Edwards Lifesciences Corporation

Methods and performing valvuloplasty

The present invention relates to apparatus and methods for performing valvuloplasty. In some embodiments, the apparatus includes an expandable braid valvuloplasty device.
Boston Scientific Scimed, Inc.

Leaflet for low gradient prosthetic heart valve

A low pressure gradient prosthetic heart valve for implant in a human. The valve includes a support frame with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area.
Edwards Lifesciences Corporation

Suture and repairing a heart

Devices and methods for treating or repairing a heart are disclosed. The device includes at least one radially expandable tissue-engaging element, an elongate member (e.g., suture) coupled to the expandable element, and a locking mechanism (e.g., locking clip, suture knot).
Edwards Lifesciences Corporation

Method and system for assessing mental state

A computer-implemented method of assessing a mental state of a subject (106) includes receiving (302), as input, a heartbeat record (200) of the subject. The heartbeat record comprises a sequence of heartbeat data samples obtained over a time span which includes a pre-sleep period (208), a sleep period (209) having a sleep onset time (224) and a sleep conclusion time (226), and a post-sleep period (210).
Medibio Limited

Heartbeat adjustment method, apparatus, and terminal

Embodiments of the present invention disclose a heartbeat adjustment method, an apparatus, and a terminal. The method includes: acquiring a network holding time period of an application program; acquiring an initial heartbeat of the application program, and acquiring a to-be-adjusted heartbeat of the application program according to the network holding time period and the initial heartbeat; and acquiring at least one preset unified heartbeat, and adjusting the to-be-adjusted heartbeat according to the at least one preset unified heartbeat to obtain an adjusted heartbeat, where the adjusted heartbeat coincides with a unified heartbeat in the at least one unified heartbeat.
Huawei Technologies Co., Ltd.

Implementing automatic switchover

One or more techniques and/or computing devices are provided for automatic switchover implementation. For example, a first storage controller, of a first storage cluster, may have a disaster recovery relationship with a second storage controller of a second storage cluster.
Netapp Inc.

Mitochondrial non-coding rnas for predicting disease progression in heart failure and myocardial infarction patients

The present invention relates to a method for predicting mortality of a test patient with chronic heart failure comprising based on detecting the expression level of one or more long non-coding rnas (lncrnas) selected from seq id nos 1 to 8. The present invention also relates to a method for predicting cardiac remodeling after myocardial infarction in a test patient based on detecting the expression level of one or more lncrnas selected from seq id nos 1 to 8..
Centre Hospitalier Universitaire Lille (chu)

Dipping mandrel with a gap

A mandrel for molding polymer valve leaflets for heart valve prostheses is disclosed, including a body portion including an outer surface with ridges and contoured surfaces corresponding to the leaflets, the upper edge of the contoured surfaces corresponding to the free upper edge of the leaflets, and the mandrel including a mandrel extension above the body portion, and a gap extending around the mandrel between the upper edge of the contoured surface and the mandrel extension. A process for producing these polymer valve leaflets is also disclosed by dip coating with this mandrel and removing the polymer film created at the gap, preferably by applying suction or blowing thereto..
St. Jude Medical, Inc.

Counterpulsation device driver apparatus, method and system

A method of operating a counterpulsation device (cpd) in a human or animal subject is disclosed, the method including: receiving a heart beat signal indicative of the heart beat of the subject; providing counterpulsation therapy by controlling the pressure supplied to a cpd drive line in pneumatic communication with the cpd to cause the cpd to alternately fill with blood and eject blood with a timing that is determined at least in part based on the heart beat signal; while providing counterpulsation therapy, receiving a cpd drive line pressure signal indicative of the pressure in the cpd drive line; and adjusting the pressure supplied to the drive line based at least in part on the drive line pressure signal.. .
Abiomed, Inc.

Implant delivery capsule

A delivery system for delivering a stent-mounted heart valve, or other implant, through an introducer sheath. The delivery system includes an elongate catheter supporting a capsule.
Edwards Lifesciences Corporation

Implant with anchoring device for heart valve disease

An implant with anchoring device for heart valve disease comprises a cardiac valve prosthesis (1), at least two sets of anchoring needles (2) and at least two sets of anchoring needle releasing devices (3). Proximal end of the anchoring needles (2) are provided with anti-disengagement ends (23).
Ningbo Jenscare Biotechnology Co., Ltd.

Methods and endovascular heart valve replacement comprising tissue grasping elements

A method for endovascularly replacing a patient's heart valve including the following steps: endovascularly delivering an anchor and a replacement valve supported within the anchor to a vicinity of the heart valve in a collapsed delivery configuration, the anchor having grasping elements adapted to grasp tissue in a vicinity of the heart valve; expanding the anchor, thereby rotating the grasping elements; and grasping the tissue with the rotating grasping elements.. .
Boston Scientific Scimed, Inc.

Dry prosthetic heart valve packaging system

Packaging for prosthetic heart valves including an assembly for stabilizing dry prosthetic tissue implants such as heart valves during storage. The packaging assembly includes a primary sterile barrier feat permits gas sterilization of the tissue implant, and a secondary sterile barrier that prevents oxidation of the implant during storage.
Edwards Lifesciences Corporation

Systems and methods for reducing respiratory-induced motion artifacts for accelerated imaging

In some aspects, the disclosed technology relates to reducing respiratory-induced motion artifacts for accelerated imaging. In one embodiment, magnetic resonance data may be acquired for an area of a subject containing the heart.
University Of Virginia Patent Foundation

Heart rate detection with multi-use capacitive touch sensors

This document describes heart rate detection with multi-use capacitive touch sensors. Fluctuations in capacitance are detected (802) using capacitive touch sensors.
Google Inc.

Apparatus and processing a subject-specific value based on beat-to-beat information

A system for measuring heart rate variability (hrv) comprising 3 sub-systems: a data collection sub-system, a data analysis sub-system, and an output sub-system. A patient is connected to a heart monitoring device such as an ecg and the data collection sub-system records the patients heart beats, and an ecg chart is produced from which the patient's hrv value is derived by the data analysis sub-system.
Lev-el Diagnostics Of Heart Diseases Ltd.

Automated segmentation of organ chambers using deep learning methods from medical imaging

Systems and methods are disclosed for automatically segmenting a heart chamber from medical images of a patient. The system may include one or more hardware processors configured to: obtain image data including at least a representation of the patient's heart; obtain a region of interest from the image data; organize the region of interest into an input vector; apply the input vector through a trained graph; obtain an output vector representing a refined region of interest corresponding to the heart based on the application of the input vector through the trained graph; apply a deformable model on the obtained output vector representing the refined region of interest; and identify a segment of a heart chamber from the application of the deformable model on the obtained output vector..
The Regents Of The University Of California

Neurostimulation titration process

Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A titration process is used to gradually increase the stimulation intensity to a desired therapeutic level.
Cyberonics, Inc.

Systems for establishing supplemental blood flow in the circulatory system

A blood circulation assist system comprising an inflow cannula having a lumen and an insertion device configured to be received therein and to facilitate insertion of a portion of the inflow cannula into a heart chamber. The insertion device includes a shaft having distal and proximal end portions and a plurality of lumens.
Circulite, Inc.

Systems and methods for providing cardiac electrophysiological markers

Systems and methods are provided to detect a multi-domain ecg waveform and display one or more cardiac electrophysiological markers. Electrical impulses are detected between at least one pair of electrodes adapted to be located near a beating heart and are converted to an ecg waveform.

Exercise device, sensor and determining body parameters during exercise

A noninvasive light sensor for detecting heart beat signals has a circular support member engageable circumferentially with a body part of a person. There are a plurality of light emitters and light detectors located around a circumference of the circular support member for respectively emitting light signals into different areas of tissue surrounding the body part, and receiving reflected light signals from the different areas of tissue surrounding the body part..
Well Being Digital Limited

Sound channel configuration method and apparatus and earphone device

Embodiments of the present application provide a sound channel configuration method and apparatus and an earphone device. The method includes: obtaining heartbeat transmission signals at two earpieces in pair; and performing sound channel configuration on signals of the two earpieces at least according to the heartbeat transmission signals at the two earpieces.
Beijing Zhigu Rui Tuo Tech Co., Ltd

Distal tip assembly for a heart valve delivery catheter

A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip.
Medtronic Cv Luxembourg S.a.r.l.

Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve

A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly.
Medtronic, Inc.

Method and device for crimping and loading heart valve

A method of crimping and loading prosthetic heart valves comprises folding a crimping sheet to form a spiral wrapped around a heart valve; manually rolling and tightening the spiral to compress the valve inside the spiral; inserting the tightened spiral wrapped around the valve into a cannula; and displacing the valve out of the tightened spiral and into the cannula. A kit for crimping and loading the valve into a delivery device comprises a crimping sheet foldable to form a spiral wrapped around the valve, the spiral manually rollable and tightenable to compress the valve wrapped inside the spiral, so that the tightened spiral is slidably insertable into a lumen of a cannula for delivering the valve; and a plunger sized for insertion into the tightened spiral to displace the heart valve out of the spiral and into the lumen of the cannula..

Stents for prosthetic heart valves and methods of making same

A single piece stent construction having a plurality of commissure posts, each of which extends upwardly from a solid ring along a bend line and generally along a central longitudinal axis of the stent.. .
Medtronic, Inc.

Prosthetic mitral or tricuspid heart valve

Said ventricular portion (2v) has a substantially spherical or ovoid shape and comprises anchoring spikes (5v) on the side of said annular portion (2i).. .

Mitral valve assembly

A heart valve assembly has a frame having an anchoring section defined by a plurality of rows of cells, with each cell defined by a plurality of struts that encircle each cell, and a pair of legs extending from the anchoring section. The assembly also includes a leaflet assembly that has a plurality of leaflets that are stitched to the legs.
Horizon Scientific Corp.

Porcine small intestine submucosa leaflet material

A prosthetic heart valve provided herein can include a porcine small intestine submucosa (p-sis) tissue leaflet. The p-sis tissue can include multiple stacked layers that are tensioned and cross-linked to form a material having a thickness of between 50 microns and 0.33 mm.
Boston Scientific Scimed, Inc.

Cultured cell leaflet material

A prosthetic heart valve provided herein can include a cultured cell tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member.
Boston Scientific Scimed, Inc.

Heart valves prostheses and methods for percutaneous heart valve replacement

Prosthetic heart valve devices and associated methods for percutaneous heart valve replacement are disclosed herein. A transcatheter valve prosthesis configured in accordance herewith includes a frame having a valve support and one or more support arms coupled thereto.
Medtronic Vascular, Inc.

A physiological parameter measuring apparatus is configured to perform a screening for a likelihood of the critical congenital heart disease, based on the oxygen saturations at two locations on a body of a patient and the difference between the oxygen saturations, and to display the likelihood as a result of the screening. The physiological parameter measuring apparatus manages, with respect to each patient, a scheduled time for starting the screening, the result of the screening, and information relating to the patient.
Nihon Kohden Corporation

Enabling application functions responsive to biometric input from more than one person

A method includes running an application on a mobile computing device, the mobile computing device accepting biometric input, and the mobile computing device enabling one or more function of the application only in response to the biometric input indicating that more than one person is present in the same location. Examples of suitable biometric input include a fingerprint, heartbeat, iris scan, facial recognition, and voice recognition.
Lenovo Enterprise Solutions (singapore) Pte. Ltd.

Aav vectors for vascular gene therapy in coronary heart disease and peripheral ischaemia

The invention relates to the provision of a gene therapy for coronary heart disease and peripheral ischemia in mammals. One embodiment is an adeno-associated viral vector (aav vector) comprising a first gene encoding a myocardin-related transcription factor a (mrtf-a).

Pharmaceutical composition and neoangiogenesis/revascularization useful in treating ischemic heart disease

A pharmaceutical composition and a method of treating ischemic heart diseases by growing new blood vessels that supply oxygen and nutrients to infarcted heart tissues throughout the entire infarct zone and for preventing cardiomyocyte apoptosis in ischemic events. The pharmaceutical composition contains an active ingredient compound with a backbone structure of formula (i)..
Lead Billion Limited

Replacement heart valve

A delivery catheter dilates the valve while the frustoconical leaflet support system enables the valve to function (open and close) during the deployment process. Unlike prior prosthetic valves that only allow valve expansion, the valve of the invention may be collapsed if needed in order to re position or retrieve the valve..

Surgical delivery device and use

A delivery device for a stented heart valve comprises a handle, an elongate shaft extending from a distal end of the handle, and a conical housing having a proximal end coupled to the elongate shaft and an open distal end, the conical housing having a conical lumen therein with a first internal diameter adjacent to the proximal end of the conical housing and a larger second internal diameter adjacent to the open distal end of the conical housing.. .
Medtronic 3f Therapeutics, Inc.

Prosthetic valve for replacing a mitral valve

Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion.
Edwards Lifesciences Corporation

Heart valve assembly systems and methods

heart valve assembly systems and methods configured for medical interventional procedures. In one aspect, the methods and systems involve a modular approach to treatment..
Caisson Interventional, Llc

Heart valve assembly comprising twofold sealing

The present invention relates to a heart valve assembly (1000), comprising a frame (1) and a heart valve (100), wherein the frame (1) supports the heart valve (100) or is interconnected thereto, preferably by sewing or sewing alone, the frame (1) comprising at least a first guiding structure (2a) for guiding at least one tension thread (5) for folding and/or unfolding the frame (1) around or along the frame (1), preferably at an outside or an outer circumference of the guiding structure (2a), wherein the heart valve (100), comprises at least two leaflets (101, 101′, 101″); an interconnecting tissue (301) interconnecting the leaflets (101, 101′, 101″) with the frame; wherein the interconnecting tissue (301) or parts thereof, respectively, is interconnected to at least one of the guiding structures (2a, 2b) such that it covers the guiding structure (2a, 2b) or parts thereof at an inner circumference of the guiding structure (2a, 2b) and such that it also covers at least both an upper part (2c) and a lower part (2d) of the outer circumference of the guiding structure (2a, 2b).. .
Venus Medtech (hangzhou), Inc.

Resting heart rate monitor system

It is an object of the present invention to provide a heart rate monitor system (10) which is able to determine the resting heart rate in an effective and unobtrusive manner. In an aspect of the present invention, a heart rate monitor system (10) comprising an inactivity determining unit (320) for determining periods of inactivity (ip) of a user based on motion data (md) detected by at least one motion sensor (200) attached to the user and a resting heart rate calculating unit (330) for calculating a resting heart rate (rhr) of the user based on heart rate data (hr) detected by at least one heart rate sensor (100) attached to the user during the periods of inactivity (ip) as determined by the inactivity determining unit (320) is provided..
Koniniklijke Philips N.v.

Pulmonary hypertension biomarker

Pulmonary hypertension is a progressive disease of various origins that is associated with vascular remodelling and results in right heart dysfunction. Accumulating evidence indicates important roles of immune cells and inflammatory chemokines in the pathogenesis and progression of pulmonary hypertension.
Novartis Ag

Methods for delivery of heart valve devices using intravascular ultrasound imaging

Methods related to delivery of various heart valve implants are described. The implant may be delivered using an ultrasound imaging delivery system.
Millipede, Inc.

Transcatheter pulmonary ball valve assembly

A heart valve assembly has a frame comprising an anchoring section, a generally cylindrical leaflet support section, and a neck section that transitions between the anchoring section and the valve support section. The anchoring section has a ball-shaped configuration defined by a plurality of wires that extend from the leaflet support section, with each wire extending radially outwardly to a vertex area where the diameter of the anchoring section is at its greatest, and then extending radially inwardly to a hub.
Horizon Scientific Corp.

Leaflet in configuration for function in various shapes and sizes

A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end. The heart valve further includes a plurality of commissure features disposed on the stent, and a collapsible and expandable valve assembly, the valve assembly including a plurality of leaflets connected to the plurality of commissure features, each of the plurality of leaflets having a free edge and being configured to have a tension line aligned near the free edge to prevent backflow..
St. Jude Medical, Cardiology Division, Inc.

Subannular sealing for paravalvular leak protection

A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent extending between a proximal end and a distal end. The stent includes an annulus section adjacent the proximal end and having a first diameter, a plurality of first struts forming cells, and a plurality of second struts connected to the annulus section and forming a plurality of deflecting cells expandable to define a second diameter larger than the first diameter.
St. Jude Medical, Cardiology Division, Inc.

Heart valve with integrated stent and sewing ring

A sewing ring for prosthetic heart valves that is connected and configured to pivot outward. A biocompatible fabric covering surrounds at least a portion of the sewing ring, and the ring may be exclusively connected to a stent with the fabric.
Edwards Lifesciences Corporation

Trileaflet mechanical prosthetic heart valve

A mechanical prosthetic heart valve having a ring, multiple hinges, and multiple leaflets. The hinges are attached to the ring and are evenly spaced from one another along the inner circumference of the ring.
Clover Life Sciences Inc.

Shock wave valvuloplasty with multiple balloons

Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device includes three balloons that are each sized and shaped to fit within a concave portion of a valve cusp when inflated with a liquid and a shock wave source within each of the three balloons.
Shockwave Medical, Inc.

Quantitative heart testing

heart condition and function can be quantified using repolarization measures and/or repolarization indices derived from a time-frequency transform of an electrocardiogram, e.g., based on points in time associated with the t wave. The electrocardiograms, time-frequency maps derived therefrom, and/or indices obtained by analysis of the time-frequency maps and electrocardiograms may be assembled into a user interface.

User interfaces for heart test devices

heart condition and function can be visualized and/or quantified using time-frequency maps derived from the time-frequency transform of one or more electrocardiograms. The electrocardiograms, time-frequency maps derived therefrom, and/or indices obtained by analysis of the time-frequency maps and electrocardiograms may be assembled into a user interface.





Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Heart for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Heart with additional patents listed. Browse our RSS directory or Search for other possible listings.


2.0874

file did exist - 12834

2 - 1 - 257