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Heart patents

      

This page is updated frequently with new Heart-related patent applications.

SALE: 390+ Heart-related patent PDFs



new patent Weight scale and corresponding preventing advancement of congestive heart failure
A weight scale (100) for assisting with management of congestive heart failure and other ailments includes a housing (101) that can define a substantially flat planar surface (102). A weight measurement device (202) measures a weight of a user.
Medline Industries, Inc.


new patent Mesh enclosed tissue constructs
A heart valve leaflet including a thermoplastic polyurethane (tpu) mesh material that has a stiffness that is comparable to a native heart valve leaflet, such that it functionally mimics a native heart valve leaflet. The heart valve leaflets optionally include one to three layers of cells cultured on each side of the mesh material.
The Regents Of The University Of California


new patent Novel methods
Provided are uses of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the treatment or prophylaxis of transplant rejection and the protection of the heart during heart surgery. Provided is the use of selective aquaporin inhibitors, e.g., of aquaporin-4 (aqp4) or aquaporin-2 (aqp2) for the treatment or prophylaxis of transplant rejection and for the protection of the heart during heart surgery..
Aeromics, Inc.


new patent Devices and methods for the treatment of heart valve insufficiencies
Disclosed herein are various embodiments directed to a device for minimally invasive medical treatment. The device being a hollow tube with a first end, a second end, and one or more anchors configured to extend outward from the exterior of the hollow tube.
Valcare, Inc.


new patent Collapsible cardiac implant and deployment system
A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site.
Edwards Lifesciences Corporation


new patent Heart chamber prosthetic valve implant with elevated valve section and single chamber anchoring for preservation, supplementation and/or replacement of native valve function
Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device with an elevated valve section and comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed..
4c Medical Technologies, Inc.


new patent Heart chamber prosthetic valve implant with base, spring and dome sections with single chamber anchoring for preservation, supplementation and/or replacement of native valve function
Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed..
4c Medical Technologies, Inc.


new patent Heart chamber prosthetic valve implant with base, mesh and dome sections with single chamber anchoring for preservation, supplementation and/or replacement of native valve function
Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed..
4c Medical Technologies, Inc.


new patent Two stage cellularization strategy for the fabrication of bioartificial hearts
In some embodiments, the present disclosure pertains to a method of fabricating an artificial heart muscle (ahm) patch. In some embodiments, the method comprises obtaining and/or isolating cells from a subject.
University Of Houston System


new patent Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage
A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame.
Edwards Lifesciences Corporation


new patent

Apparatus and intra-cardiac mapping and ablation

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a maze procedure.
Kardium Inc.

new patent

Dual energy x-ray coronary calcium grading

Methods and apparatus for grading coronary calcium, including an example apparatus that includes a set of logics and a memory that stores a set of radiographic images. The set of logics includes an image acquisition logic that acquires a set of radiographic images of a region of tissue, the set of radiographic images including a low-energy reference x-ray image and a higher-energy floating x-ray image, a registration logic that produces a set of registered images from a plurality of members of the set of radiographic images, an enhancement logic that produces a set of calcium-enhanced images from the set of registered images, a post-enhancement logic that produces a bone image from the set of calcium-enhanced images, and a grading logic that computes a coronary heart disease prediction score based, at least in part, on the bone image and a set of features extracted from the bone image..
Case Western Reserve University

new patent

Sensors for prosthetic heart devices

Prosthetic heart devices may be implanted into the heart with a sensor coupled to the device, the sensor being configured to measure physiological data, such as blood pressure, in the heart. Devices that may employ such sensors include prosthetic heart valves and occlusion devices, although sensor systems may be deployed in the heart separate from other implantable devices.
St. Jude Medical, Cardiology Division, Inc.

new patent

Identifying ecg signals having the same morphology

A method, including selecting an initial set of electrocardiograph (ecg) signals taken over a single heartbeat of a human subject, the set having respective morphologies to be used as a template for an arrhythmia of the subject, and receiving a subsequent set of ecg signals taken over a subsequent heartbeat of the human subject. The method also includes performing a cross-correlation between the initial set and the subsequent set, so as to generate a correlation coefficient that is a measure of a goodness of fit between geometries of the initial set and the subsequent set, and, when the correlation coefficient exceeds a threshold coefficient, accepting the subsequent heartbeat as having been caused by the arrhythmia..
Biosense Webster (israel) Ltd.

Realtime feedback response system and methods of using the same

Provided herein are apparatus and methods of relaxation. In particular, disclosed herein includes a system that provides realtime or near realtime feedback response to a user in order to achieve a relaxation response.

Systems and methods for treating pulmonary hypertension

A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit.
Aria Cv, Inc.

Devices for remodeling a valve annulus and ventricle

Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member..
Edwards Lifesciences Corporation

Delivery system with inline sheath

Systems and methods for delivering and implanting heart valves are disclosed. The delivery systems can include an integrated introducer.
Medtronic, Inc.

Delivery systems for prosthetic heart valve

A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion.
Edwards Lifesciences Corporation

Delivery devices for implantable medical devices and methods of manufacturing same

This disclosure describes, among other things, methods, devices, and systems for non-invasive evaluation of a patient's vascular system and custom design and manufacture of one or more components of a delivery device for delivery and deployment of an implantable medical device, such as a prosthetic heart valve. For example, a delivery sheath can be 3d printed to have varying durometers at one or more areas along its length and/or circumference so that it can more easily bend and flex as it traverses particularly tortuous anatomical features..
Medtronic Vascular, Inc.

Valve leaflet attachment in collapsible prosthetic valves

A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition. The stent includes a plurality of cells, each cell being formed by a plurality of struts, and a plurality of commissure features.
St. Jude Medical, Cardiology Division, Inc.

Prosthetic heart valve using pericardium and manufacturing same

A prosthetic heart valve using a pericardium is disclosed where: three hetero-biological tissue slices, which are extracted in a quadrangular shape from a bovine pericardium or a porcine pericardium, are prepared; each hetero-biological tissue slice is folded so as to form an inner tissue slice inside and an outer tissue slice outside, the outer tissue slice being longer than the inner tissue slice; each of the inner tissue slice and outer tissue slice is coupled by sewing in a semicircular shape with a first coupling thread such that each inner tissue slice forms a pulmonic valve slice inside the first coupling thread and a fixing slice outside the first coupling thread such that each hetero-biological tissue slice is formed in a cylindrical shape by allowing each slice to be adjacent to each other. The disclosed prosthetic heart valve has increased durability and prevents reverse blood flow..
Taewoong Medical Co., Ltd.

Methods and apparatuses for remodeling tissue of or adjacent to a body passage

Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating a patient having congestive heart failure.
Vessix Vascular, Inc.

System and non-invasive measurement of pressure inside a body including intravascular blood pressure

A device system and method for the non-invasive ultrasound measurement of the intravascular blood pressure is presented, wherein the blood pressure measurements are performed by means of the registration of the distances changes between the surface of the active piezoelectric transducer radiating an ultrasound beam into the localization area of the blood vessel or the heart chamber and the surface elements of the passive ultrasound beam reflector implanted into the blood vessel or the heart chamber. The invention is applicable to any medium transparent for ultrasound waves with the need to measure pressure changes of the liquid..
Pi-harvest Holding Ag

Automatic heart rate diagnostics

In some examples, processing circuitry of a medical device system determines, for each of a plurality of periods, a plurality of heart rates of a patient based on a cardiac electrogram signal, and identifies a first subset of the plurality of heart rates as nighttime heart rates and a second subset of the plurality of heart rates as resting heart rates. The processing circuitry determines a representative nighttime heart rate based on the first subset of the plurality of heart rates, determines a representative resting heart rate based on the second subset of the plurality of heart rates, and determines a nocturnal dip base on the representative nighttime heart rate and the representative resting heart rate.
Medtronic, Inc.

Introduced to electromedical equipment for automated triage of newborn with possible congenital heart defects

The present patent refers to improvements introduced in electromedical equipment, applied to automated triage of newborn babies with purpose to detect possible congenital heart defects by means of little heart test, through dedicated software (ds) implanted in memory (1-g), georeference block (1-m), pendrive (3), external hd (4), energy and supply assembly (e) provided with dc02215v j4 connector, cable and power supply, plug (p) positioned at the rear panel of the apparatus (1), internal and external connections (c) with magnets arranged into two rows at the rear part of the apparatus (1), of “c”-shape metallic base (2) with two front flanges (2-a), aiming to increase the number of users, increase flexibility of test protocol and change the usability in order to minimize errors, bringing advantages of higher testing speed, improved interface with user, better measurement quality, lower cost, higher usage versatility, and lighter weight and smaller size of equipment.. .
Hi Technologies Sa

Lockstep networking

Exemplary methods, apparatuses, and systems configure a recurring heartbeat for a first field device to operate in synchronization with a second field device and a base station. The first field device turns off radio power for a hibernation period.
Gthrive, Inc

Real-time user authentication using integrated biometric sensor

A computing device includes a housing, a processor, memory, a human interface device (i.e., a keyboard or a trackpad), and a biometric sensor integrated into the housing. The biometric sensor is configured for capturing biometric data (i.e., heartbeat data or a vein scan) from one or more of hands of a user of the device while the user's fingers are interacting with the human interface device.
Google Inc.

Vagus nerve and carotid baroreceptor stimulation system

Systems and methods are provided for delivering vagus nerve stimulation and carotid baroreceptor stimulation to patients for treating chronic heart failure and hypertension. The vagus nerve stimulation and carotid baroreceptor stimulation therapies may be provided using a single implantable pulse generator, which can coordinate delivery of the therapies..
Cyberonics, Inc.

Biological valve for venous insufficiency

A bioprosthetic valve for repairing a deep venous insufficiency in a subject includes a single leaflet from a xenogeneic heart valve attached at natural margins of attachment to a patch of valve wall tissue. The patch may extend axially above and below the leaflet and circumferentially on either side of the leaflet to provide a region for attaching the patch to a fenestration in a host vein.
Hancock Jaffe Laboratories, Inc.

Treatment of cardiac remodeling and other heart conditions

The present disclosure provides novel methods for treating cardiac remodeling and heart conditions using specific compounds, as well as compositions, and pharmaceutical formulations. In some embodiments, the compounds may inhibit acetylation of mef2 transcription factors..
University Of Miami

Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves

Apparatus and methods are described herein for use in the delivery and deployment of a prosthetic mitral valve into a heart. In some embodiments, an apparatus includes a catheter assembly, a valve holding tube and a handle assembly.
Tendyne Holdings, Inc.

Retaining mechanisms for prosthetic valves

Prosthetic valve systems for replacing a native valve exhibiting regurgitation comprises a support structure and a transcatheter heart valve (thv) that is separate from the support structure. The support structure can be configured to be positioned such that it extends annularly around the native valve leaflets.
Edwards Lifesciences Corporation

Prosthetic heart valve

A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame.
Edwards Lifesciences Corporation

Retaining mechanisms for prosthetic valves

Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native leaflets of a valve.
Edwards Lifesciences Corporation

Apparatuses and methods for cutting a tissue bridge and/or removing a heart valve clip or suture

Disclosed is an instrument having an elongated shaft, a first member configured in the elongated shaft such that the first member can be deployed from a first portion of the instrument. The first member, when deployed, is configured over a tissue bridge within a heart, the tissue bridge having a clip or suture.
Mitracore Technologies Inc.

Drowsiness detection program medium, drowsiness detection method, and drowsiness detection apparatus

A drowsiness detection method that causes a computer to execute a process, the process includes: performing frequency analysis on heartbeat data obtained from a subject; and determining a state of the subject by calculating entropy in a predetermined frequency bandwidth with a peak as a reference, where the peak is within a predetermined frequency range of frequency distribution obtained from the frequency analysis result, determining that the subject is in a relaxation state in a case where the calculated entropy is less than a predetermined threshold value, and determining that the subject is in a drowsiness state in a case where the entropy is equal to or greater than the threshold value.. .
Fujitsu Limited

File transmission method, apparatus, and distributed cluster file system

A file transmission method includes: obtaining file information of a to-be-transmitted file from a distributed coordination node cluster; determining that at least one slave push node stores the to-be-transmitted file according to the file information of the to-be-transmitted file and heartbeat information of the at least one slave push node; wherein the heartbeat information of the at least one slave push node contains file information stored in the at least one slave push node, and the to-be-transmitted file is retrieved by the at least one slave push node from a file storage node cluster; generating a file transmission path, wherein the file transmission path comprises at least one destination node cluster; sending the file transmission path to the at least one slave push node, so that the at least one slave push node sends the to-be-transmitted file to the at least one destination node cluster through the file transmission path.. .
Tencent Technology (shenzhen) Company Limited

Monitoring of replicated data instances

Replicated instances in a distributed computing environment provide for automatic failover and recovery. A component monitors the status of event processors in a set or bucket and handles the failure of an event processor.
Amazon Technologies, Inc.

Catheter system for implantation of prosthetic heart valves

The invention relates to a catheter for the transvascular implantation of prosthetic heart valves, in particular comprising self-expanding anchorage supports (10), which allow a minimally invasive implantation of prosthetic heart valves. The aim of the invention is to reduce the risk to the patient during the implantation.
Jenavalve Technology, Inc.

Heart valve assembly

A heart valve assembly has a heart valve assembly that has a wire frame comprising an anchor section, a generally cylindrical valve support section, and a neck section that transitions between the anchor section and the valve support section. The wire frame includes a plurality of supports extending radially outwardly in an annular manner about an upper end of the valve support section, and the anchor section has an annular flange that extends radially therefrom, so that an annular space is defined between the annular flange and the annular supports for receiving or capturing the native annulus when the heart valve is deployed.
Venus Medtech (hangzhou) Inc.

Replacement heart valve prosthesis

A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body.
Edwards Lifesciences Corporation

Methods for improved prosthetic heart valve with leaflet shelving

Described embodiments are directed toward prosthetic valve leaflets of particular configurations that control bending character. In embodiments provided herein, valve leaflets are operable to bend along a base of the valve leaflets..
W. L. Gore & Associates, Inc.

Prosthetic heart valve having improved commissure supports

A prosthetic heart valve can comprise a radially collapsible and expandable annular frame and a leaflet structure comprising a plurality of leaflets mounted within the frame. The frame can have commissure attachment portions that are configured to support the commissures of the leaflets in unique ways.
Edwards Lifesciences Corporation

Indication of risk for coronary artery disease

A way of indicating a risk for coronary artery disease is disclosed. A first plurality of first sound recordings of heartbeats and second plurality of second sound recording of the ambient background are obtained.
Acarix As

Method of monitoring health while using a toilet

A method of obtaining health data of a toilet user using one or more sensors is disclosed. One or more sensors are used by a toilet user while the toilet user is using the toilet to take health measurement readings of the user.

Polyurethanes

Partially crosslinked polyurethane polymers comprising diisocyanates and aliphatic hydrocarbon soft segments with a short-chain diol chain extender and a multifunctional amine and/or alcohol crosslinker to provide a polyurethane polymer with useful properties for the production of medical implant devices such as heart valves, are described. The polymers have an unexpected linear elastic region in a range from 5-100% and preferably between 10-35%.
Strait Access Technologies Holdings (pty) Ltd

Vagus nerve stimulation and subcutaneous defibrillation system

Systems and methods are provided for delivering vagus nerve stimulation and cardioversion/defibrillation therapies to patients for treating chronic heart failure. The vagus nerve stimulation and cardioversion/defibrillation therapies may be provided using a single implantable pulse generator, which can coordinate delivery of the therapies to provide an acute vagus nerve stimulation therapy in advance of delivering cardioversion-defibrillation energy..
Cyberonics, Inc.

Devices, heart valve replacement

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include a valve support having an upstream end and a downstream end extending around a longitudinal axis and having a cross-sectional shape.
Twelve, Inc.

Mechanical heart valve prosthesis for the right ventricle

A prosthetic heart valve having a pair of cooperating leaflets mounted in a valve body to alternate between an open position where the flow of blood in a downstream direction is permitted and a closed position where the flow of blood in the reverse direction is counteracted. Pivot member sets at diametrically opposite sides of each leaflet guide the leaflets moving between the open and closed positions, each set including an ear or a recess cooperating with an associated cavity or knob of an interior surface of the valve body.
Academisch Ziekenhuis Groningen

Holder for heart valve prostheses, corresponding storage arrangement, delivery instrument and kit

A holder for a heart valve prosthesis, the holder including a hub portion having a longitudinal axis, an engagement portion coupled to the hub portion and including plural finger members variably positionable relative to the hub portion between a collapsed condition wherein the finger members are closed onto the hub portion and an expanded condition wherein the finger members radially protrude with respect to the hub portion to engage a heart valve prosthesis.. .
Sorin Group Italia S.r.l.

Heartbeat-signal detecting device

A heartbeat-signal detecting device, which is for detecting a heartbeat signal of a living body, includes: (a) a gas-flow sensor configured to detect a flow rate of exhalation and inhalation passing through a trachea of the living body; (b) a gas-flow calculation controlling portion configured to output a respiration signal that reflects a respiratory motion of the living body, based on a signal outputted from the gas-flow sensor; (c) a waveform analysis controlling portion configured to extract, from the respiration signal, frequency components which are in synchronization with a pulse of a heart of the living body superimposed on the respiration signal, and to output a heartbeat signal representing a heartbeat waveform of the living body; and (d) a heartbeat-signal evaluation controlling portion is configured to evaluate a functional abnormality or an anatomic abnormality of the heart, based on the heartbeat signal analyzed by the waveform analysis controlling portion.. .
National University Corporation Nagoya University

Feature point identification mechanocardiography

A method to identify feature points associated with the heart valve movement, heart contraction or cardiac hemodynamics is revealed. The mechanocardiography (mcg) is a technology that makes use of vibrational waveforms acquired using at least one gravity sensor attached on one of the four heart valve auscultation sites on the body surface.
Chang Gung University

Methods and systems for obtaining physiologic information

The present invention discloses methods suitable for obtaining information related to at least one physiologic parameter of a person belonging to the group comprising respiration rate, heart rate, respiration rate variability, heart rate variability, temporal characteristics of at least a part of a heartbeat, and temporal characteristics of at least a part of a respiration cycle in a non-contact fashion. The present invention also discloses systems suitable for obtaining information related to at least one physiologic parameter of a person belonging to said group of physiologic parameters in a non-contact fashion..

Electronic monitoring, security, and communication device assembly

A method, system, and apparatus for security and monitoring are disclosed. In one embodiment, a small device with five sensors (temperature, light, motion, accelerometer, sound) includes a processor, local data storage, and wifi and bluetooth communication capabilities.
Rph Engineering, Llc

Heart valve sewing cuff

An embodiment of the invention includes a sewing cuff for aortic heart valves that better approximates native anatomy by better mating with the crown-like anatomical annulus. Limiting distortion of the crown-like annulus provides better blood flow and overall valve function and provides a physician greater ease of implantation since native anatomy is not flattened.
On-x Life Technologies, Inc.

Left heart assist device and method

A device, a kit and a method is presented for permanently augmenting the pump function of the left heart. The mitral valve plane is assisted in a movement along the left ventricular long axis during each heart cycle.
Synergio Ag

Coherent single layer high strength synthetic polymer composites for prosthetic valves

Thin, biocompatible, high-strength, composite materials are disclosed that are suitable for use in a prosthetic valve for regulating blood flow direction. In one aspect, the leaflet material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as a prosthetic heart valve leaflet.
W. L. Gore & Associates, Inc.

Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent

The invention relates to a prosthetic heart valve (100) for an endoprosthesis (1) used in the treatment of a stenotic cardiac valve and/or a cardiac valve insufficiency. The prosthetic heart valve (100) comprises of a plurality of leaflets (102), which consist of a natural and/or synthetic material and have a first opened position for opening the heart chamber and a second closed position for closing the heart chamber, the leaflets (102) being able to switch between their first and second position in response to the blood flow through the heart.
Jenavalve Technology, Inc.

Docking station for heart valve prosthesis

An anchoring device that can be positioned within a native valve, such as the native mitral valve, to secure a replacement prosthetic valve in place. The anchoring device can comprise a docking station formed of a super elastic wire-like member defining a continuous, closed shape.
Edwards Lifesciences Corporation

Device and treating vascular insufficiency

Embodiments of a leaflet clip device and method of reducing regurgitation through a native heart valve are disclosed. A leaflet clip device can include an elongated clipping member having a first end portion and a second end portion and a tensioning mechanism coupled to the clipping member.
Edwards Lifesciences Corporation

Stationary intra-annular halo designs for paravalvular leak (pvl) reduction - active channel filling cuff designs

A prosthetic heart valve may include a collapsible and expandable stent extending in a flow direction between a proximal end and a distal end, a cuff attached to an annulus section of the stent and having an outer surface facing in a radial direction orthogonal to the flow direction, a plurality of prosthetic valve leaflets attached to the cuff, and a sealing structure attached to the annulus section of the stent at an inner edge of the sealing structure. The flow direction may be defined from the proximal end toward the distal end.
St. Jude Medical, Cardiology Division, Inc.

Apparatus and intra-cardiac mapping and ablation

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a maze procedure.
Kardium Inc.

Magnetic navigation systems and methods

Systems and methods for forming a lesion on an endocardial tissue of a patients heart involve placing an ablation assembly inside of the heart and adjacent to the endocardial tissue, and placing a guiding assembly outside of the heart. An ablation assembly includes an ablation element and a first attraction element, and a guiding assembly includes a second attraction element.

Methods and devices for valve clip excision

A system for excising an implanted clip approximating opposed valve leaflets in a heart valve includes a capture catheter configured to be introduced proximate the valve leaflets on one side of the clip, a transfer catheter configured to be introduced proximate the valve leaflets on another side of the clip, and a cutting tool configured to be deployed between the capture and transfer catheters and to be engaged against tissue of at least one of the valve leaflets and to excise the clip. A removal catheter may optionally be used to remove the clip from the heart..
Revive Medical, Llc

Systems and methods to determine surrogates of blood pressure

Embodiments of the present disclosure relate to systems and methods for determining a subject's blood pressure using one or more implantable medical devices (imds). In an embodiment, a medical system comprises: at least one implantable medical device configured to sense signals associated with heart sounds of a subject and a processing unit communicatively coupled to the at least one implantable medical device.
Cardiac Pacemakers, Inc.

Identifying heartbeat messages

Examples relate to identifying heartbeat messages. In one example, a computing device may: obtain a plurality of messages that includes incoming messages and outgoing messages, each incoming message being sent from a server device to a client device, and each outgoing message being sent from the client device to the server device; identify candidate message pairs, each candidate message pair including one incoming message and one outgoing message; and identify a heartbeat message pair from the candidate message pairs based on at least one of: plurality of timestamps that includes i) incoming message timestamps that each correspond to one of the incoming messages, and ii) outgoing message timestamps that each correspond to one of the outgoing messages; a number of occurrences of each candidate message pair included a message log; or characteristics of data included in the incoming message and outgoing message of each candidate message pair..
Entit Software Llc

Remotely configurable routers with failover features, and methods and reliable web-based administration of same

Web-enabled routers are remotely and securely administered in a centralized fashion. A router receives a configuration profile from a dedicated web domain that maintains a repository of configuration profiles for multiple routers.
Datto, Inc.

Systems and methods for detecting wireless communication jamming in a network

An electronic device may include a processor and a network interface that may include a first radio and a second radio. The processor may be configured to perform wireless communication jamming attack detection by occasionally performing clear channel verification utilizing the network interface to determine whether a threshold number of devices' channels are incapacitated in a wireless network within a threshold amount of time and/or by sending a heartbeat signal from the first radio and determining whether the second radio received the heartbeat signal..
Google Inc.

Method of treating or ameliorating type 1 diabetes using fgf21

Methods of treating metabolic diseases and disorders using a fgf21 polypeptide are provided. In various embodiments the metabolic disease or disorder is type 1 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels, diabetic nephropathy, neuropathy, retinopathy, ischemic heart disease, peripheral vascular disease and cerebrovascular disease.
Amgen Inc.

Method of treating ischemic heart disease

A method of treating ischemic heart disease can include administering a therapeutically effective amount of a composition including date seed nanoparticles to a subject in need thereof. Exemplary suitable dosage forms can include tablet, gel, paste, and suspension.
King Abdulaziz University

Prosthetic heart valve devices and methods of valve repair

A mechanism for adjusting the chordae connecting the leaflets of a mitral valve to the papillary muscles in order to restore normal functioning of the mitral valve. The devices or mechanisms can correct problems associated with both prolapsed leaflets and restricted leaflets to allow the leaflets to properly coapt, thereby preventing or minimizing regurgitation.
Medtronic, Inc.

Systems and methods for heart valve therapy

Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks.
Caisson Interventional, Llc

Method for replacing a heart valve

A method for replacing a native heart valve in need thereof comprises delivering to the native heart valve an apparatus comprising a valve member, a connecting member, and an anchor member suitable for anchoring the apparatus. The valve member reversibly moves between an open position and a closed position to augment or replace the function of the native valve leaflets, thereby reducing valve regurgitation.
Edwards Lifesciences Ag

Methods for anchoring a heart valve prosthesis in a transcatheter valve implantation procedure

Methods of deploying and securing a heart valve prosthesis are disclosed. A heart valve prosthesis (100) having a plurality of anchor guides (212) is loaded within a catheter-based delivery device, wherein each of the anchor guides is releasably engaged by a respective elongate member (338) and wherein tensioning of the elongate members aids in collapsing the prosthesis during loading.
Medtronic Vascular, Inc.

Inflatable transcatheter intracardiac devices and methods for treating incompetent atrioventricular valves

Inflatable heart valve implants and methods utilizing those valves designed to reduce or eliminate the regurgitant jet associated with an incompetent atrioventricular valve. The heart valve implants, which are deployed via a transcatheter venous approach, comprise an inflatable balloon portion movably connected to an anchored guide shaft and movable from a distal position in the ventricle to a more proximal position between leaflets of a native atrioventricular valve.

System and replacing an inflamed or infected heart valve

The invention relates to a system for replacing a heart valve that is diseased owing to inflammation and/or an infection. The system has: a stent system with at least one expandable stent; and a replacement heart valve which is secured to the at least one stent and has at least two heart valve leaflets.

Device and transcatheter heart valve repair under triangular resection technique

Medical device for transcatheter heart valve repair comprising a grasping tweezer (1) and a plicating tweezer (2), said grasping tweezer (1) being adapted to grasp a leaflet rim (3) and said plicating tweezer (2) comprising two rotatable flaps (4,5) and a central shaft (6) around which said flaps (4,5) may rotate in a “butterfly manner”, in such a way that the plicating tweezer (2) may adopt a closed or an open configuration. The invention also relates to a method for using this medical device..
Epygon

Toilet with a health monitoring torso belt

A toilet torso belt with sensors is disclosed. The torso belt is used by a toilet user while the toilet user is using the toilet to take health measurement readings of the user.

Baby sleep monitor

A sleep monitor for monitoring baby sleep uses sleep state classification based on heartbeat feature respiration features. The sleep monitor automatically retrains the classification during use of the sleep monitor.
Koninklijke Philips N.v.

Non-invasive measuring myocardial ischemia, stenosis identification, localization and fractional flow reserve estimation

The present disclosure facilitates the evaluation of wide-band phase gradient information of the heart tissue to assess, e.g., the presence of heart ischemic heart disease. Notably, the present disclosure provides an improved and efficient method to identify and risk stratify coronary stenosis of the heart using a high resolution and wide-band cardiac gradient obtained from the patient.
Analytics For Life

Dynamic heartbeating mechanism

System and method for providing failover protection for a cluster of host computers operates in one of two modes. When the number of host computers in the cluster is equal to or less than a threshold number, the host computers in the cluster operate in an all-active heartbeating mode in which each of the host computers is enabled to function as a master node.
Vmware, Inc.

Video display device system, heartbeat specifying method, heartbeat specifying program

A video display system capable of detecting heartbeat of a user by being mounted on the head of a user when used is provided. The video display system comprises a video display device that is mounted on the head of a user when used and a heartbeat detection device that detects the heartbeat of the user is provided, wherein video display device includes an acceleration sensor that sequentially outputs measured acceleration information and a first transmission unit that sequentially transmits the acceleration information to the heartbeat detection device, and the heartbeat detection device includes a first reception unit that receives the acceleration information transmitted from the video display device and a heartbeat detection unit that detects the heartbeat of the user from a waveform indicating a change in acceleration based on the received acceleration information..
Fove, Inc.

Prognosis of adverse events in patients with suspected chronic heart failure

The present invention is in the field of clinical diagnostics. Particularly the present invention relates to the prognosis of adverse events in patients with stable chronic heart failure or being suspected of having stable chronic heart failure by determination of the level of procalcitonin (pct)..
B.r.a.h.m.s. Gmbh

1,3-dihydroimidazole-2-thione derivatives as inhibitors of dopamine-beta-hydroxylase

Compounds of formula i and a method for their preparation are described, where r1, r2 and r3 are the same or different and signify hydrogens, halogens, alkyl, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; r4 signifies -alkyl-aryl or alkyl heteroaryl; x signifies ch2, oxygen atom or sulphur atom; n is 2 or 3; including the individual (r)- and (s)-enantiomers or mixtures of enantiomers thereof; and including pharmaceutically acceptable salts and esters thereof. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure..
Bial - Portela & Ca, S.a.

Implantable leadless pacemaker with atrial-ventricular synchronized pacing

An implantable leadless pacemaker (ilp) for a human or animal heart, wherein the ilp includes a housing, at least two electrode poles for picking up electrical potentials and/or delivering electrical stimulation, a stimulation control unit in connection with the electrode poles, a sensing unit that is in connection with at least one electrode pole, a signal processing unit in connection with the sensing unit, a signal evaluation unit in connection with the signal processing unit and/or the sensing unit, and an energy source. The sensing unit is configured to sense a first signal associated with an activity of the first heart chamber, and the stimulation control unit is configured to deliver electrical stimulation in the first heart chamber via the at least two electrode poles.
Biotronik Se & Co. Kg

Implantable leadless pacemaker with atrial-ventricular synchronized pacing

An implantable leadless pacemaker (ilp) for a human or animal heart is provided that includes a housing, at least two electrode poles for picking up electrical potentials and/or delivering electrical stimulation, a stimulation control unit in connection with the electrode poles, a sensing unit that is in connection with at least one electrode pole, a signal processing unit in connection with the sensing unit, a signal evaluation unit in connection with the signal processing unit and/or the sensing unit, and an energy source. The sensing unit is configured to sense a first signal associated with an activity of the first heart chamber, and the stimulation control unit is configured to deliver electrical stimulation in the first heart chamber via the at least two electrode poles.
Biotronik Se & Co. Kg

Method for reversing, preventing, delaying or stabilizing soft tissue calcification

The present invention provides methods of treating soft tissue calcification in a subject, comprising a step of administering to said subject an effective amount of ferric organic compound, such as ferric citrate. The claimed methods may prevent, reverse, delay or stabilize soft tissue calcification in a subject having chronic kidney disease.
Panion & Bf Biotech, Inc.

Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (ppar) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension.
Ardelyx, Inc

Compact crimping device

A compact crimping mechanism well-suited for use with devices such as stented prosthetic heart valves. The crimping mechanism includes a plurality of jaws configured for coordinated inward movement toward a crimping axis to reduce the size of a crimping iris around a stented valve.
Edwards Lifesciences Corporation

Prosthetic heart valve with compressible frames

A tubular portion of a valve frame circumscribes a longitudinal axis, and defines a lumen along the axis and a plurality of valve-frame coupling elements disposed circumferentially around the axis. An outer frame: (a) comprises a ring defined by a pattern of alternating peaks and troughs, the pattern having an amplitude, (b) comprises a plurality of legs, coupled to the ring at respective troughs, and (c) is shaped to define a plurality of outer-frame coupling elements, each coupled to the ring, and fixed with respect to a respective valve-frame coupling element.
Mitraltech Ltd.

Heart valve prosthesis

A device for artificial cardiac valve support, the device including an upstream portion designed to expand to have at least one dimension wider than a native heart valve annulus, a downstream portion attached to the upstream portion, the downstream portion also designed to expand to have at least a portion with at least one dimension wider than a native heart valve annulus, and a plurality of artificial valve commissure posts. A method for producing a device for artificial cardiac valve support, the method including producing an upstream portion, producing a downstream portion, and attaching the upstream portion to the downstream portion, producing a frame for artificial cardiac valve support.
Mitrassist Medical Ltd.

Modified consensus protocol for eliminating heartbeat network traffic

A computing system in data communication with a plurality of nodes that make up a distributed computing cluster can detect an absence of communication from a node of the plurality of nodes over a time period that exceeds a predefined threshold time period. The computing system can query an instance of a central topology manager for the plurality of nodes regarding liveness of the node from which the absence of communication was detected and can attempting to re-initiate communication with the node when the instance of the central topology manager indicates that the node is live..
Sap Se

Method and system for creating and managing aggregation service hierarchies

Techniques disclosed herein provide an approach for creating and managing aggregation service hierarchies, such as hierarchies used in distributed scheduling services and heartbeat services. In one embodiment, management nodes accept host computer registration events and add host computers to a hierarchy used as the aggregation mechanism in an aggregation service.
Vmware, Inc.

Semi-automated heart valve morphometry and computational stress analysis from 3d images

A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (fea) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3d transesophageal echocardiography (rt-3dtee).
The Trustees Of The University Of Pennsylvania

Pooled memory heartbeat in shared memory architecture

Examples provide a pooled memory heartbeat for virtual machine hosts. A virtual controller creates a pooled memory heartbeat file system in a shared memory partition of a pooled memory.
Vmware, Inc.

Method of site isolation protection, electronic device and system using the same method

A method of site isolation protection includes the following steps. A set of clustered engines including a first engine at a first site and a second engine at a second site is provided.
Weixu Technology Co. Ltd.

Centrifugal pumps for medical uses

Extracorporeal circuit devices can be used for on-pump open-heart surgery to support surgical procedures such as coronary artery bypass grafting. In some cases, a centrifugal pump is used as part of an extracorporeal circuit.
Terumo Cardiovascular Systems, Inc.

Methods and renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease.
Medtronic Ardian Luxembourg S.a.r.l.

Integral artificial heart device

Integral artificial heart device capable of storing venous blood in dynamic atria, without interrupting the continuous return of the blood. The device comprises a right ventricle (a1) and left ventricle (a2) pulsing simultaneously, and the reactive right atrium (c1) and left atrium (not illustrated) thereof, immersed in a pneumatic spec (d) having a variable vacuum d, which is driven by a solenoid (35), acting sequentially, by repulsion, on the permanent magnet discs (20, 21) included in the elastic ventricular membranes (18, 19), which beat simultaneously in the ventricular spaces (a1) and (a2), and, in the opposite direction, in pneumatic space (d) which houses elastic tubes acting as atria.

Centrifugal pumps for medical uses

Extracorporeal circuit devices can be used for on-pump open-heart surgery to support surgical procedures such as coronary artery bypass grafting. In some cases, a centrifugal pump is used as part of an extracorporeal circuit.
Terumo Cardiovascular Systems, Inc.

Modulators of the prostacyclin (pgi2) receptor useful for the treatment of disorders related thereto

The present invention relates to amide derivatives of formula (xiiia) and pharmaceutical compositions thereof that modulate the activity of the pgi2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pulmonary arterial hypertension (pah); idiopathic pah; familial pah; pah associated with a collagen vascular disease, a congenital heart disease, portal hypertension, hiv infection, ingestion of a drug or toxin, hereditary hemorrhagic telangiectasia, splenectomy, pulmonary veno-occlusive disease (pvod) or pulmonary capillary hemangiomatosis (pch); pah with significant venous or capillary involvement; platelet aggregation; coronary artery disease; myocardial infarction; transient ischemic attack, angina; stroke; ischemia-reperfusion injury; restenosis; atrial fibrillation; blood clot formation in an angioplasty or coronary bypass surgery individual or in an individual suffering from atrial fibrillation; atherosclerosis; atherothrombosis; asthma or a symptom thereof; a diabetic-related disorder such as diabetic peripheral neuropathy, diabetic nephropathy or diabetic retinopathy; glaucoma or other disease of the eye with abnormal intraocular pressure; hypertension; inflammation; psoriasis; psoriatic arthritis; rheumatoid arthritis; crohn's disease; transplant rejection; multiple sclerosis; systemic lupus erythematosus (sle); ulcerative colitis; ischemia-reperfusion injury; restenosis; atherosclerosis; acne; type 1 diabetes; type 2 diabetes; sepsis; and chronic obstructive pulmonary disorder (copd)..
Arena Pharmaceuticals, Inc.

Systems and methods for manufacturing a stent frame

A prosthetic heart valve can include a support structure, an actuator member, and a plurality of leaflets. The support structure can have a plurality of struts and a plurality of rivets.
Edwards Lifesciences Cardiaq Llc

Integrated heart valve delivery system

An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent.
Edwards Lifesciences Corporation

Heart valve prosthesis with outer skirt

A heart valve prosthesis includes a heart valve encircled by a base body in a peripheral direction to hold the heart valve. The heart valve is fastened to the base body and arranged in its interior.
Biotronik Ag

Delivery system for percutaneous delivery and implantation of atrioventricular heart valves

Described is a delivery system for percutaneous delivery and implantation of a heart valve. The delivery system includes a handle with a sheath extending therefrom.
The Regents Of The University Of California

System and positioning an artificial heart valve at the position of a malfunctioning valve of a heart through a percutaneous route

Method for positioning an artificial heart valve at the anatomic position of a malfunctioning heart valve of a heart of a patient, by employing a catheter bearing the artificial heart valve and a valve fixation device, at the tip of the catheter, the method including the procedures of receiving a marking input associated with an image of the heart, and respective of the anatomic position, in a medical positioning system (mps) coordinate system, moving the tip toward the anatomic position, constantly detecting the current position of the artificial heart valve, and producing an indication when the current position substantially matches the anatomic position, thereby enabling the catheter to fix the malfunctioning heart valve in place, by the valve fixation device.. .
Mediguide Ltd.

Method for the detecting electrocardiogram anomalies and corresponding system

A heart-rate associated with a heartbeat signal is determined. A transform is selected based on the determined heart-rate associated with the heartbeat signal and a reference heart-rate associated with a dictionary of a sparse approximation model.
Politecnico Di Milano

Congenital heart disease monitor

A congenital heart disease monitor utilizes a sensor capable of emitting multiple wavelengths of optical radiation into a tissue site and detecting the optical radiation after attenuation by pulsatile blood flowing within the tissue site. A patient monitor is capable of receiving a sensor signal corresponding to the detected optical radiation and calculating at least one physiological parameter in response.
Masimo Corporation

Application agnostic sensor, control computer and methods for operating

A server computer includes a non-transitory data storage storing a plurality of control rule sets including a first control rule set and a second control rule set, an interface transmitting, over a network, the first control rule set in response to a signal from the multi-application-transceiver device such that loading of application specific settings of the first control rule set causes a first health monitoring application to be enabled on the multi-application-transceiver device, and a health data analyzer receiving, over the network, a processed signal from the multi-application-transceiver device, where the processed signal includes information relating to monitoring a heartbeat or breathing of the person, detection of sudden infant death syndrome (sids) of the person, or detection of a concentration of macromolecules on the person. The health data analyzer performs an analysis on the processed signal, and communicates, over the network, results of the analysis to the multi-application-transceiver device..

Sealing structure for heart valve implants

A heart valve implant comprising a supporting stent, a heart valve element, and a skirt, the skirt includes or is formed of at least one molded body, wherein the molded body is made of dried treated bacterial cellulose that has a swelling capacity that is greater than untreated bacterial cellulose of the same type.. .
Biotronik Ag

System and cardiac valve repair and replacement

A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween..

Transcatheter valve delivery system with crimped prosthetic heart valve

Stented prosthetic heart valve crimping tools and methods, and transcatheter delivery systems for delivering a crimped prosthetic heart valve. Methods of the present disclosure include crimping or compressing a stented prosthetic heart valve via spherical compression to a spherically compressed shape, and then delivering the so-shaped prosthesis to a target site.
Medtronic Vascular, Inc.

Replacement heart valve

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve.
Edwards Lifesciences Cardiaq Llc

Replacement heart valve

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve.
Edwards Lifesciences Cardiaq Llc

Methods and systems for multi-site stimulation

Systems and methods for multi-site cardiac stimulation are disclosed. The system includes an electrostimulation circuit to deliver electrostimulation to one or more candidate sites of at least one heart chamber.
Cardiac Pacemakers, Inc.

Compositions and use of a-type procyanidins

The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing a-type procyanidins, and methods of use thereof, for prophylactic or therapeutic treatment of a human or a veterinary animal to treat or prevent no-responsive health conditions, treat hypertension, cardiovascular disease, coronary artery disease and/or vascular circulation disorders, prevent or reduce the risk of heart attack, stroke, congestive heart failure and/or kidney failure, or to improve blood flow, for example renal blood flow. The composition may optionally contain an additional no modulating agent and/or a cardiovascular-protective or therapeutic agent, or may be administered in combination with such an agent..
Mars, Incorporated

Heart valve leaflet capture device

The invention provides a heart valve leaflet capture device (250) comprising a cardiac catheter probe having a proximal end for manipulating the device (250) and a distal end terminating in a transvalve element (256). The transvalve element (256) is configured to pass through a heart valve generally parallel to a longitudinal axis of the catheter and includes two or three leaflet gripping elements (252).
Strait Access Technologies Holdings (pty) Ltd

Transcatheter prosthetic heart valve delivery system with protective feature

Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a covering feature associated with the spindle for selectively covering at least a portion of a stented prosthetic heart valve tethered to the spindle in a delivery state.
Medtronic Vascular, Inc.

Transcatheter prosthetic heart valve delivery system with lateral offset control

Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature.
Medtronic Vascular, Inc.

Method of replacing mitral valve

A method of implanting a prosthetic mitral heart valve includes advancing a guidewire through a femoral vein, an atrial septum, and a native mitral valve. A guide catheter is advanced over the guidewire and a delivery catheter is advanced through the guide catheter.
Edwards Lifesciences Coporation

Crimping device

A crimping system for a prosthetic heart valve comprises an elongate rigid body and a radially flexible, tubular sock. The body has an inner lumen extending along a central longitudinal axis between an insertion end and an outlet end.
Edwards Lifesciences Corporation

Transcatheter valve delivery system with septum hole closure tip assembly

Transcatheter heart valve delivery systems having a tip assembly configured to close the hole or perforation made in a patient's septal wall after transseptal delivery of a stented prosthetic heart valve to a defective heart valve (e.g., a mitral valve). The delivery device is configured to permit in vivo release of the tip assembly immediately after deployment of the stented prosthetic heart valve to implant the tip assembly into the septal wall proximate the hole through which the stented prosthetic heart valve is delivered.
Medtronic Vascular, Inc.

Foot pulse oximeter for screening congenital heart disease before newborn discharge

A method including placing a portion of a foot of a newborn in a device, the device including a light emitter and a corresponding receiver coupled on opposite sides of the device, the device further including a processor for processing data from the light emitter and receiver; and determining a presence of congenital heart disease. An apparatus including a body including a chamber of a size to accommodate a portion of a newborn's foot; at least one light emitter and a corresponding detector coupled on opposite sides of the body, the emitter configured to emit light of a prescribed wavelength into the chamber; and a processor coupled to the body and configured to receive a signal from the at least one detector..
Los Angeles Biomedical Research Institute At Harbor-ucla Medical Center

Link management method, device and system in virtual machine environment

At least some embodiments of invention provide a method, device and system for link management in a virtual machine (vm) environment. The method includes: a heartbeat handshake link is established with a vm.
Zte Corporation

Methods for treating hypercholesterolemia

Disclosed herein are antisense compounds and methods for decreasing ldl-c in an individual having elevated ldl-c. Additionally disclosed are antisense compounds and methods for treating, preventing, or ameliorating hypercholesterolemia and/or atherosclerosis.
Ionis Pharmaceuticals, Inc.

Blood treatment machine having electrical heartbeat analysis

A blood treatment machine includes a blood pump; an arterial line in fluid communication with the blood pump; a venous line; and a heartbeat evaluation system including (i) a first electrode coupled to the arterial line or to a patient, (ii) a second electrode coupled to the venous line, (iii) electronic circuitry communicating electrically with the first electrode and the second electrode to sense an electrical heartbeat signal generated by the patient, and (iv) signal processing configured to use the sensed heartbeat signal to calculate at least one of (a) heart rate, (b) respiration, (c) stroke volume, (d) cardiac output, or (e) central blood volume.. .
Baxter Healthcare Sa

Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (ppar) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension.
Ardelyx, Inc.

Implantable prosthetic valve with non-laminar flow

A prosthetic heart valve can include an expandable support stent, a valve assembly, and a connecting membrane. The support stent can have first and second end portions and can be configured to be radially expandable from a first configuration to a second configuration.
Edwards Lifesciences Corporation

Replacement valve and anchor

Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve.
Boston Scientific Scimed, Inc.

Automated condition screening and detection

Embodiments are disclosed that enable an electronic device to instruct as user how to user one or more noninvasive sensors to measure one or more physiological parameters of a patient. In one embodiment, the measured parameters are used to obtain a diagnosis, such as a diagnosis of a critical congenital heart defect..
Masimo Corporation

Method for the detecting electrocardiogram anomalies and corresponding system

A heartrate monitor detects heartbeats in a test signal. A local heartrate and an energy of acceleration are associated with the detected heartbeats.
Politecnico Di Milano

Auxiliary component for an equipment for cardiac autonomic neuropathy test and equipment that includes such a component

Equipment for carrying out cardiac autonomic neuropathy tests includes a base unit to which a mouthpiece is connected, forming an autonomous system for measuring the pressure and/or the pattern of breath, provided with a series of leds aimed at informing a patient, who is undergoing the test, about correctness or incorrectness of a test execution. The mouthpiece is provided with a flow sensor, aimed at measuring a patient's pattern of breath, and a pressure sensor.
Meteda S.r.l.

Flow-based adaptive private network with multiple wan-paths

Systems and techniques are described which improve performance, reliability, and predictability of networks without having costly hardware upgrades or replacement of existing network equipment. An adaptive communication controller provides wan performance and utilization measurements to another network node over multiple parallel communication paths across disparate asymmetric networks which vary in behavior frequently over time.
Talari Networks Incorporated

Method and device for processing failure in at least one distributed cluster, and system

A method and a device for processing a failure in at least one distributed cluster, and a system, where the at least one distributed cluster includes a first distributed cluster. The first distributed cluster includes a first master node, a first slave node, a first reference node, and a first secondary node that serves as a backup of the first master node.
Huawei Technologies Co., Ltd.

Machine learning system for assessing heart valves and surrounding cardiovascular tracts

A machine learning system for evaluating at least one characteristic of a heart valve, an inflow tract, an outflow tract or a combination thereof may include a training mode and a production mode. The training mode may be configured to train a computer and construct a transformation function to predict an unknown anatomical characteristic and/or an unknown physiological characteristic of a heart valve, inflow tract and/or outflow tract, using a known anatomical characteristic and/or a known physiological characteristic the heart valve, inflow tract and/or outflow tract.
Stenomics, Inc.

System and non-invasively controlling autonomic nerve activity using skin

System and methods for monitoring and/or controlling nerve activity in a subject are provided. In one embodiment, a system includes electrodes configured to be placed proximate to a subject's skin, and a signal detector configured to detect electrical signals using the electrodes.
Indiana University Research & Technology Corporation

Corkscrew shape for right-sided cardiac device

A catheter includes a catheter body, a pump assembly and a cannula. The pump assembly can be disposed at a distal end of the catheter body and has a distal portion.
Abiomed, Inc.

Transcatheter prosthetic heart valve and delivery system

A prosthetic heart valve for an endoprosthesis used in the treatment of a stenotic heart valve and/or a heart valve insufficiency. The prosthetic heart valve comprises a plurality of leaflets (3,4,5) which are able to switch between their open and close position in response to the blood flow through the heart.

Replacement heart valve implant with inflow stitching

A replacement heart valve implant may include a tubular anchor member actuatable between a delivery and a deployed configuration, the tubular anchor member including an inflow end, an outflow end, and a plurality of anchor member intersection points, and defining a longitudinal axis extending from the inflow end to the outflow end, a plurality of valve leaflets, and a seal member secured to the tubular anchor member at the inflow end. An end surface of each of the plurality of valve leaflets may abut an inner-facing surface of the seal member.
Boston Scientific Scimed, Inc.

Prosthetic heart valve with cusp positioners

A prosthetic heart valve has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. A support frame including three cusp positioners is fixed with respect to a leaflet frame and located intermediate each pair of adjacent commissure regions.
Edwards Lifesciences Corporation

Patient specific scan parameters for mri scanning

A method of optimizing scan parameters for lge-mri. At least one cardiac mri ti scout scan is performed by applying an inversion pulse every predetermined heartbeat of a patient.
University Of Utah Research Foundation

High-impedance fault detection using coordinated devices

A conductor-mounted device (cmd) used to signal an intelligent electronic device (ied) of the existence of a fault on a portion of the electric power delivery system is described herein. The cmd may provide a heartbeat signal to the ied.
Schweitzer Engineering Laboratories, Inc.

Methods and renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease.
Medtronic Ardian Luxembourg S.a.r.l.

Compositions and methods for treating heart failure

The present invention provides methods for treating chronic heart failure patients using the medication comprising neureplin. The methods comprise first performing a companion diagnostic test of each patient before treatment; and then providing a suitable treatment to the patient according to the results of the companion diagnostic test.
Zensun (shanghai) Science & Technology, Co., Ltd.

Mitral valve delivery device

A delivery device for a collapsible prosthetic heart valve may include a catheter assembly and an operating handle. The catheter assembly may include an inner shaft around which a compartment is defined, and a distal sheath having proximal and distal segments configured to enclose the compartment.
St. Jude Medical, Cardiology Division, Inc.

Heart valve implant and methods for delivering and implanting same

heart valve implants and methods for implanting and delivering same are described. A heart valve implant can include a shaft, having a first end and a second end, an anchor, and a plurality of wafers.
Cardiosolutions, Inc.

Stented prosthetic heart valve with variable stiffness and methods of use

A prosthetic heart valve including a stent frame and a valve structure. The valve structure is disposed within a lumen of the stent frame.
Medtronic Vascular Galway

Mitral heart valve replacement

A prosthetic heart valve having an inflow end, an outflow end and a longitudinal axis extending from the inflow end to the outflow end includes a collapsible and expandable stent including a plurality of cells arranged in at least one row extending around a circumference of the stent. The stent further includes at least one engaging arm joined to one of the cells adjacent the outflow end and having a free end extending toward the inflow end, the engaging arm being movable between a loaded condition in which the engaging arm is oriented substantially parallel with the longitudinal axis of the stent, a partially-released condition in which the engaging arm forms a first angle with the longitudinal axis of the stent, and a fully-released condition in which the engaging arm forms a second angle with the longitudinal axis of the stent, the first angle being larger than the second angle..
St. Jude Medical, Cardiology Division, Inc.

Heart valve with stent having varying cell densities

A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent extending between a proximal end and a distal end, the stent including an annulus section adjacent the proximal end and an aortic section adjacent the distal end. The annulus section has cells arranged in at least one annulus row, each annulus row having a same first number of cells, the first number defining a first cell density.
St. Jude Medical, Cardiology Division, Inc.

Suturing rings for prosthetic heart valves

The present subject matter describes a suturing rings and method of manufacture of suturing rings for prosthetic heart valves. A plurality of suture holes are formed along a length of the metal sheet by performing punching or similar operations.

Replacement heart valve implant with invertible leaflets

A locking mechanism for a medical implant may include a buckle member, a post member axially translatable with respect to the buckle member, the post member including a receiving portion proximate a proximal end of the post member, a distal end, a laterally-arched central body portion extending between the receiving portion and the distal end, and a cantilevered leg extending proximally from the distal end, and an actuator element including a proximal shaft portion and a distal engagement portion, the distal engagement portion being configured to releasably engage the receiving portion of the post member. The proximal shaft portion may be pivotable with respect to the distal engagement portion..
Boston Scientific Scimed, Inc.

Remote monitoring device

A remote monitoring device is connected to a rubber strap and contains: a controller, a global system for mobile communication (gsm), a global positioning system (gps), a wi-fi & blue tooth, and a near field communication (nfc). The controller includes a microprocessor, a blood pressure sensing unit, a heartbeat sensing unit, a temperature sensing unit, and a wireless signal transmitting unit.

Method for extracting heart information based on micro movements of human body

A method of extracting heart information from a body micro-movement is provided. The method includes a face tracking step, a frame difference averaging step, smoothing filtering step, and a sliding peak detection step..
Sangmyung University Industry-academy Cooperation Foundation

Biomarkers and methods of prediction

Subject of the present invention are biomarkers and methods for the identification of risk for subsequent cardiovascular event (e.g. Coronary heart disease death, non-fatal myocardial infarction, ischemic stroke, hospitalizations for unstable angina pectotis, cardiac arrest) in patients that have experienced an acute coronary syndrome, comprising the detecting the level of nt-probnp, homocysteine and crp..
Hoffmann-la Roche Inc.

Neurostimulation in a neural fulcrum zone for the treatment of chronic cardiac dysfunction

Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone.
East Tennessee State University

Heart valve delivery catheter with safety button

Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. Catheter assemblies according to the present invention can include a handle assembly, an introducer sheath, and a distal tip assembly.
Medtronic, Inc.

Systems of heart valve delivery on a beating heart

A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex.
Edwards Lifesciences Corporation

Elastomeric leaflet for prosthetic heart valves

A leaflet for a prosthetic valve formed of at least one layer that includes a composite material containing at least one expanded fluoropolymer membrane having serpentine fibrils and an elastomer is provided. The fluoropolymer may be polytetrafluoroethylene.
W. L. Gore & Associates, Inc.

Everting heart valve

The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve.
Boston Scientific Scimed, Inc.

Leaflet stitching backer

A replacement heart valve post and leaflet assembly may include at least a first post member including a body portion, a cantilevered leg portion, and a hinge portion configured to connect the body portion and the cantilevered leg portion and one or more leaflets. The cantilevered leg portion may comprise a longitudinally extending slot defined therein.
Boston Scientific Scimed, Inc.

Apparatus and methods for anterior valve leaflet management

In some embodiments, a method includes delivering to a native valve annulus (e.g., a native mitral valve annulus) of a heart a prosthetic heart valve having a body expandable from a collapsed, delivery configuration to an expanded, deployed configuration. The method can further include, after the delivering, causing the prosthetic heart valve to move from the delivery configuration to the deployed configuration.
Tendyne Holdings, Inc.

System for screening of the state of oxygenation of a subject

The present invention relates to a processor and a system (1, 1′) for screening of the state of oxygenation of a subject (100), in particular for screening of newborn babies for congenital heart disease. The system comprises an imaging unit (2) for obtaining a plurality of image frames of the subject (100) over time, and a processor (3) for processing the image frames.
Koninklijke Philips N.v.

Method and detection of heartbeat characteristics

Aspects of the present disclosure are directed to detecting atrial fibrillation (af). As may be implemented in accordance with one or more embodiments, a time series of inter-beat intervals is computed from a recording of activity of a beating heart.
Vivaquant Llc

System and providing an indication of the well-being of an individual

Systems and methods for providing an indication of the well-being of an individual are disclosed. In particular, the systems and methods utilizes data obtained from physical sensors such as heartbeat monitors and social media platforms for deriving and/or assigning an indication of the individual's feelings or emotional well-being, are described..

Heartbeat period setting method, and terminal

Embodiments of the present invention disclose a heartbeat period setting method, including: setting a heartbeat period of a tested application to t2 and performing a first heartbeat test; setting heartbeat periods of multiple applications to ti if the first heartbeat test is not passed, and performing heartbeat services; or setting the heartbeat period of the tested application to t3 if the first heartbeat test is passed, and performing a second heartbeat test; and setting the heartbeat periods of the multiple applications to t2 if the second heartbeat test is not passed, and performing heartbeat services; or setting the heartbeat period of the tested application to t4 if the second heartbeat test is passed, and performing a third heartbeat test, where t1<t2<t3<t4. The embodiments of the present invention further disclose a corresponding mobile terminal.

Service providing device, alternative service providing device, relaying device, service providing system, and service providing method

A service providing device included in a process control system in a plant, the service providing device includes a communicator configured to perform communication via a network, a service provider configured to provides a service via the communicator by exclusively assigning first identification information to one of the service providing device and an alternative service providing device, the first identification information being common to the alternative service providing device which provides the service instead of the service providing device, and a heartbeat transmitter configured to transmit heartbeat information for notifying that the service is normal to the alternative service providing device via a relaying device by using second identification information which is different from the first identification information.. .

Storage network element discovery method and apparatus

A storage network element discovery method and an apparatus, where the method includes broadcasting or multicasting, by a control network element, a heartbeat message to at least one storage network element, where the heartbeat message includes address information of the control network element, receiving, by the control network element, a response message returned by at least one storage network element according to the heartbeat message, and determining an accessible storage network element according to the response message, where the response message includes network parameter information of the corresponding storage network element. Therefore, in a storage array, by broadcasting or multicasting a heartbeat message and according to a reply from a storage network element, a control network element may determine a storage network element that can be accessed by the control network element..

Device and regulating pressure in a heart chamber

A device for regulating blood pressure in a heart chamber is provided. The device includes a shunt positionable within a septum of the heart.

Short acting phenylalkylamine calcium channel blockers and uses thereof

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods..

Short acting phenylalkylamine calcium channel blockers and uses thereof

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods..

Short acting phenylalkylamine calcium channel blockers and uses thereof

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods..

Prosthetic heart valve devices with tethered anchors and associated systems and methods

Prosthetic heart valve devices with tethered anchors and associated systems and methods are disclosed herein. A heart valve device configured in accordance with embodiments of the present technology can include, for example, a valve support for carrying a prosthetic valve.

Expandable epicardial pads and devices and methods for delivery of same

Apparatus and methods are described herein for use in the delivery of a prosthetic mitral valve. In some embodiments, an apparatus includes an epicardial pad configured to engage an outside surface of a heart to secure a prosthetic heart valve in position within the heart.

Truncated cone heart valve stent

A heart valve stent having a section with a heart valve implant and several proximally disposed tissue anchors, also comprising a plurality of anchoring threats, each with a proximate end fastened to the stent or valve and a distal end attached to tissue within a heart chamber to provide tension between the heart chamber tissue and the stent.. .

Stent assembly for use in prosthetic heart valves

A prosthetic heart valve having a cuff attached to a stent provides a seal for preventing paravalvular leakage. The cuff may be constructed from known sealing materials to fill in and around paravalvular leakage gaps, while continuously collapsing down into a low profile volume within the stent.

Heart valve prosthesis

A heart valve prosthesis includes a valve frame (2), on which frame several valve leaflets (8) are fastened, as well as a fastening region which connects axially onto the valve frame (2), for fastening in a blood vessel. The fastening region includes a stabilizing ring (14, 14′, 14″, 14″′, 14″″) which defines a given shape and a given diameter and is connected to the valve frame (2) is a force-decoupled manner..

High-frequency device

A high-frequency device that detects biological information related to heartbeat, respiration, and the like with high accuracy. A high-frequency device (1) includes a biological signal extracting unit (heartbeat signal extracting unit 53, respiration signal extracting unit 63) that extracts a biological signal representing a specific frequency component; and an autocorrelation function processing unit (heartbeat autocorrelation function processing unit 54, respiratory autocorrelation function processing unit 64) that determines periodicity of an autocorrelation function to calculate biological information..

Health monitoring device

A computer-implemented method for processing ecg data may include: receiving ecg data representing a plurality of heartbeats; analyzing the ecg data to determine whether each of the plurality of heartbeats is a normal heartbeat or an abnormal heartbeat; associating each of the abnormal heartbeats with an existing template or a new template; receiving input related to each new template, wherein the input includes either: a) a confirmation that the new template represents an abnormal heartbeat, or b) a reclassification of the new template as representing a normal heartbeat or a different abnormal heartbeat; and in response to the user input, updating a label of each of the heartbeats associated with each confirmed new template and each of the heartbeats associated with each reclassified new template.. .

Secure labeling of network flows

An enterprise security system is improved by instrumenting endpoints to explicitly label network flows with cryptographically secure labels that identify an application or other source of each network flow. Cryptographic techniques may be used, for example, to protect the encoded information in the label from interception by third parties or to support cryptographic authentication of a source of each label.
Sophos Limited

Exercise suit with integrated weights

An exercise suit with integrated weights includes a shirt portion and a pants portion that are constructed from a lightweight elastomeric material. A plurality of soft weights are disposed along the shirt and pants portions at locations adjacent to the major muscle groups of the suit wearer.

Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis

Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both..
Concievalve Llc

Replacement heart valve with improved stitching

A replacement heart valve implant may include an expandable anchor member, a plurality of valve leaflets disposed within the anchor member, a seal member disposed about a distal portion of the anchor member, one or more whip sutures attaching a distal end of the seal member to a distal end of the plurality of valve leaflets at a joint, one or more distal lashing sutures attaching a distal portion of the seal member to a distal end of the anchor member, and a plurality of proximal lashing sutures attaching a proximal portion of the seal member to the distal portion of the anchor member, wherein the one or more distal lashing sutures does not extend through the seal member.. .
Boston Scientific Scimed, Inc.

Medical alert system

A medical alert system comprises a wearable heart monitoring device for transmitting wireless heart rate data signals to a portable computing device. A processor associated with the portable computing device processes the heart rate data signals to determine whether the signals meet pre-established triggering criteria.

Quantitative heart testing

heart condition and function can be quantified using repolarization measures and/or repolarization indices derived from a time-frequency transform of an electrocardiogram, e.g., based on points in time associated with the t wave. The electrocardiograms, time-frequency maps derived therefrom, and/or indices obtained by analysis of the time-frequency maps and electrocardiograms may be assembled into a user interface.
Heart Test Laboratories, Inc.

Managing connections for data communications using heartbeat messaging

A system, computer-implemented method and computer program performs heartbeat messaging for managing connections for data communications. In one example method, an indication of a problem associated with a connection for data communication in a computing system or network is received.

Managing connections for data communications using heartbeat messaging

A system, computer-implemented method and computer program performs heartbeat messaging for managing connections for data communications. In one example method, an indication of a problem associated with a connection for data communication in a computing system or network is received.

Device cloud monitoring and stability

An example system may include a first device connected over respective communications interfaces to a plurality of second devices. The first device may establish respective remote terminals between the first device and one or more second devices.

Methods and compositions for treating age-related disorders

The present invention relates to methods and compositions containing an antagonist of a negative regulator of gdf-11 (e.g., an antibody) for use in treating an age-related condition. In particular the methods and compositions can be used to treat an age related cardiovascular condition such as diastolic heart failure..

Fine resolution identification of a neural fulcrum for the treatment of chronic cardiac dysfunction

Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone.

Implantable neurostimulator-implemented managing tachyarrhythmic risk during sleep through vagus nerve stimulation

A patient suffering from congestive heart failure is at increased risk of cardiac arrhythmogenesis during sleep, particularly if experiencing central sleep apnea as a co-morbidity. Low intensity peripheral neurostimulation therapies that target imbalance of the autonomic nervous system have been shown to improve clinical outcomes.

Blood pump

A blood pump has a hollow body in which an impeller with a spiral blading produces an axial propulsion of blood along the impeller, as well as an at least partly actively stabilized magnetic bearing device and a hydrodynamic bearing device for the impeller. The impeller may be set into a rotation about a rotation axis of the impeller with a motor stator located outside the hollow body.

Centrifugal pump for medical use and artificial heart assist device having centrifugal pump for medical use

A centrifugal pump includes a rotating shaft, a pump substrate, a housing and an impeller. The pump substrate has a driving unit configured to rotate the rotating shaft.

Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin

The present application provides methods for treating cardiovascular conditions. The methods can include administering a transient receptor potential vanilloid 1 (trpv1) receptor agonist to an epidural space.

Percutaneous heart valve prosthesis

A percutaneous heart valve prosthesis (1) has a valve body (2) with a passage (9) extending between the first and second ends (7, 8) of the valve body (2). The valve body (2) is collapsible about a longitudinal axis (10) of the passage (9) for delivery of the valve body (2) via a catheter (18).

Methods of packaging and delivering prosthetic heart valves

An improved holder and storage system for prosthetic heart valves that pre-shields or pre-constricts the commissure posts of the valve to prevent suture looping. Pre-shielding and pre-constriction mean at the time of manufacture, so that the valves are stored with the commissure posts shielded and/or constricted.

Leaflet suturing to commissure points for prosthetic heart valve

A collapsible prosthetic heart valve includes a collapsible and expandable stent and a collapsible and expandable valve assembly. The stent has a proximal end and a distal end.

Methods for quickly implanting a prosthetic heart valve

A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent.

Collapsible prosthetic heart valves

A prosthetic heart valve includes a collapsible and expandable support frame extending between an inflow end and an outflow end and a plurality of commissures, wherein each commis sure is formed with an elongate opening. A plurality of leaflets are supported inside the support structure and operative for allowing flow in a first direction from the inflow end to the outflow end and to substantially block flow in an opposite direction from the outflow end to the inflow end.

Angiogenic treatment of ischemic heart disease

Devices, methods, systems and procedures for localized, targeted treatment of angiogenic-based therapy in at least one region of interest in one or more layers of cardiac tissue. Various methods can include diagnosing a patient with ischemic heart disease or “at-risk” of manifesting ischemic heart disease, placing the patient into a specific angiogenic-based treatment therapy group, collecting image data, confirming image data and other diagnostic test results, developing a preoperative plan to target region of interest, inserting the catheter into a heart chamber, monitoring the distal end of the catheter tip within the heart on a visual display, contacting at least one layer of cardiac tissue, creating one or more channels in the heart tissue and/or administering the angiogenic-based therapy..

Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof

The present invention provides compositions and methods based on genetic polymorphisms that are associated with cardiovascular diseases, particularly coronary heart disease (especially myocardial infarction) or hypertension. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection..
University Of Texas Board Of Regents

Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease

The invention relates to pimobendan for use in a method of reducing the heart size and/or delaying the onset of clinical symptoms in a patient suffering from asymptomatic (occult, preclinical) heart failure, preferably congestive heart failure, due to mitral valve disease (mvd), and/or delaying the onset of heart failure, preferably congestive heart failure, in a patient suffering from asymptomatic (occult, preclinical) heart failure, preferably congestive heart failure, due to mitral valve disease (mvd), wherein the patient is preferably a mammal, more preferably a human, a dog, a cat or a horse, and most preferably a dog.. .
Boehringer Ingelheim Vetmedica Gmbh

Trans-aortic delivery system with containment capsule centering device

heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly which can include a first control mechanism, a second control mechanism, and a decoupling mechanism.
Medtronic Vascular Galway

Heart valve prosthesis

A heart valve prosthesis (1), including: a stent framework (2), which can be transferred from a collapsed state into an expanded state, in which the stent framework (2) extends along an axis (a′), wherein the stent framework (2) has a plurality of struts (20, 24), which form a plurality of cells (21a, 21b, 25) connected to one another; and a heart valve (3), which is fixed to the stent framework (2). In accordance with the invention, the thickness (d′) of the struts varies in the peripheral direction (u) of the expanded stent framework (2)..
Biotronik Ag

Thorascopic heart valve repair method and apparatus

An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough.
Mayo Foundation For Medical Education And Research

Detection apparatus, detection method, and program

There is provided a detection apparatus including: a heartbeat sensor that includes a plurality of electrodes and is configured to detect a first detection signal indicating heartbeat of a detection target via the plurality of electrodes; a pulse wave sensor configured to detect a second detection signal indicating a pulse wave of the detection target; and a processing unit configured to detect a pulse of the detection target on the basis of the first detection signal and the second detection signal.. .
Sony Mobile Communications Inc.

Polygraph

A method comprising measuring skin conductivity level of a human subject responsive to a series of preliminary questions; measuring skin conductivity level of the human subject in response to a series of control questions; and in case that a sympathetic activation is detected, finding the authenticity of the response to the control question by comparing the recovery time of skin conductivity level for the control question with the basic recovery time. Further, a method comprising measuring heartbeat of a human subject responsive to a series of preliminary questions to which the answer is known, to derive a level of coherence of the heartbeat being a baseline heartbeat coherence level; presenting the human subject with a series of control questions, and finding the authenticity of a response to a relevant question by comparing the heartbeat coherence detected with the baseline heartbeat coherence and the unbalanced heartbeat coherence..
Reflection Technologies Ltd.

Method and device for managing instant communication application program, and mobile terminal thereof

A method and device for managing an instant communication application program, and a mobile terminal thereof are provided. The method includes: when an upper-layer application processor (ap) side of a mobile terminal is in a standby state, an instant communication application program is prevented from sending a heartbeat packet to a network server through the upper-layer ap side; and the instant communication application program is replaced to send the heartbeat packet of the instant communication application program to the corresponding network server..
Zte Corporation

Method for heartbeat packet processing by using proxy, apparatus, and communications system

The embodiments of the present invention provide a method for heartbeat packet processing by using a proxy, an apparatus, and a communications system. The method includes: receiving, by a host, a first heartbeat packet sent by a first application in a client, where the client is a terminal that accesses the host by using a short range communications technology; and determining, by the host according to the first heartbeat packet and a first preset list, whether the first application is included in the first preset list.
Huawei Technologies Co., Ltd.

Left heart vent catheter

A method for venting the left ventricle of a patient's heart includes the step of providing a left heart vent catheter that includes an elongate tube having a hollow passageway. The catheter is provided with a plurality of openings and a balloon near the distal end.

Apparatus for performing peritoneal ultrafiltration

An apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure, comprising a tube set including a connector for connection to a patient line for access to the peritoneal cavity of the patient. A flow pump is arranged for addition and removal outflow and inflow (recirculation) of fluid from/to the peritoneal cavity.
Triomed Ab

A device for generating bilateral pressure impulses

Disclosed is an electromechanical device generating bilateral pressure impulses, wherein the alternative and specular movement of the homologous cursors (cv, co), pacing one of the cartesian axes, exclusively manages mobile cores (nem) of electromagnets (em) with planned solicitation, for supplying the necessary mechanical energy for the correct working of operating machines of different kinds, and in particular of a permanent artificial heart.. .

Chelator-targeting ligand conjugates for cardiovascular imaging

Disclosed are methods of imaging a site in a heart of a subject to detect cardiovascular disease that involve stressing a subject, administering to the stressed subject an effective amount of a radionuclide-labeled chelator-glucose analog conjugate, and imaging the heart of the subject by detecting a signal generated by the conjugate in the heart of the subject. Also disclosed are methods of imaging a peripheral blood vessel in a subject by using a detectable amount of a radionuclide-labeled chelator-glucose analog conjugate.
Cell>point, Llc

Methods of implanting a cardiac implant with integrated suture fasteners

A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge.
Edwards Lifesciences Corporation

Method for treating an aortic valve

A method of implanting a prosthetic heart valve includes advancing the prosthetic heart valve in a radially-contracted configuration into an annulus of a native aortic valve. The prosthetic heart valve includes a self-expanding body and a plurality of leaflets fastened to the body.
Edwards Lifesciences Corporation

Surgical heart valves adapted for post-implant expansion

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander..
Edwards Lifesciences Corporation

Expandable surgical heart valve indicators

A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion.
Edwards Lifesciences Corporation

Heart valve prosthesis

Mitral valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.
Medtronic, Inc

Spacer for securing a transcatheter valve to a bioprosthetic cardiac structure

A spacer for creating a docking station for a transcatheter heart valve is provided. The spacer changes an effective diameter and/or a shape of an implanted bioprosthetic structure such as a bioprosthetic heart valve or annuloplasty ring, providing a supporting structure into which the transcatheter valve expands without over expanding.
Edwards Lifesciences Corporation

Dual sterilization containment vessel

The disclosure pertains to a vessel for holding replacement heart valves and associated positioning and installation apparatus which is configured and adapted to contain a biocidal sterilization fluid during and following exposure of a delivery system for the replacement heart valve to sterilization by ionizing radiation and methods of use therefor. The vessel includes a shield which limits exposure of biologically derived material therein to radiation.
Boston Scientific Scimed Inc.

Femoral drape

A sterile femoral drape intended to be placed over a surgical patient lying on an operating table to isolate the patient during the surgical procedure, the drape comprising a top sheet of bio-impermeable material of a length and width greater than a conventional operating table such that the top sheet fully encompasses the patient and drapes over the lateral side edges and the bottom (foot) edge of the table. Femoral access holes located proximate to the patient's groin are provided to allow access to the patient's femoral artery during heart catheterizations or other surgical procedures.

Methods & systems to determine multi-parameter managed alarm hierarchy during patient monitoring

The present specification discloses systems and methods of patient monitoring in which multiple sensors are used to detect physiological parameters and the data from those sensors are correlated to determine if an alarm should, or should not, be issued, thereby resulting in more precise alarms and fewer false alarms. Electrocardiogram readings can be combined with invasive blood pressure, non-invasive blood pressure, and/or pulse oximetry measurements to provide a more accurate picture of pulse activity and patient respiration.
Spacelabs Healthcare Llc

Closure and ablation of body viscera and conduits

Devices and methods can be used to treat heart conditions. Some such devices include endocardial occlusion and ablation devices.
Mayo Foundation For Medical Education And Research

Heartbeat detection method and heartbeat detection device

A heartbeat detection device includes a difference value calculation unit (3) for calculating, from a sampling data sequence of an electrocardiographic waveform of a living body, one of an amount of change and a degree of change of sampling data for each sampling time, a multiplication unit (4) for calculating, for each sampling time, a product by multiplying one of an amount of change and a degree of change of the sampling data at a time k by one of the sampling data at the time k and sampling data at a time before the time k by a predetermined time t, a peak detection unit (5) for detecting a peak of the product, and a heartbeat time determination unit (6) for setting time of the peak of the product as a heartbeat time.. .
Nippon Telegraph And Telephone Corporation

Monitoring a condition of a subject

Apparatus for monitoring a clinical condition of a subject is described. At least one motion sensor detects motion of the subject and generates a sensed motion signal responsive to the sensed motion.
Earlysense Ltd.





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