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Heart patents

      

This page is updated frequently with new Heart-related patent applications.

SALE: 390+ Heart-related patent PDFs



System and a blood flow simulator
A blood flow simulator generates a compression and expansion in a test fluid that emulates the pressure waveform created by a heartbeat in blood flow. The blood flow simulator stores a plurality of pressure waveform files that include actual data recorded from a heartbeat, arterial pressure waveform, or venous pressure waveform.
Sanmina Corporation


Systems and methods for arrhythmia detection
Systems and methods for detecting cardiac arrhythmias such as an atrial fibrillation (af) are described herein. The af detection system includes a sensor circuit to sense a physiological signal, a heartbeat processor to recognize a plurality of beat patterns using cycle length of two more consecutive cardiac cycles.
Cardiac Pacemakers, Inc.


Substrate having an electron donating surface with metal particles comprising palladium on said surface
There is disclosed a substrate with an electron donating surface, characterized in having metal particles on said surface, said metal particles comprising palladium and at least one metal selected from the group consisting of gold, ruthenium, rhodium, osmium, iridium, and platinum, wherein the amount of said metal particles is from about 0.001 to about 8 μg/cm2. Examples of coated objects include contact lenses, pacemakers, pacemaker electrodes, stents, dental implants, rupture nets, rupture mesh, blood centrifuge equipment, surgical instruments, gloves, blood bags, artificial heart valves, central venous catheters, peripheral venous catheters, vascular ports, haemodialysis equipment, peritoneal dialysis equipment, plasmapheresis devices, inhalation drug delivery devices, vascular grafts, arterial grafts, cardiac assist devices, wound dressings, intermittent catheters, ecg electrodes, peripheral stents, bone replacing implants, orthopaedic implants, orthopaedic devices, tissue replacing implants, intraocular lenses, sutures, needles, drug delivery devices, endotracheal tubes, shunts, drains, suction devices, hearing aid devices, urethral medical devices, and artificial blood vessels..
Bactiguard Ab


Neuregulin based methods for treating heart failure
The present invention features methods of treating patients with chronic heart failure by administering a neuregulin polypeptide within a dosage range which is both effective and safe.. .
Zensun (shanghai) Science & Technology, Co., Ltd.


Actively controllable stent, stent graft, heart valve and controlling same
A delivery apparatus comprises a handle portion and at least one rotatable drive shaft. The handle portion has an actuation mechanism and a display.
Edwards Lifesciences Cardiaq Llc


Sizing methods for a valved conduit graft
A sizing tool for use in implanting a composite valved conduit having a prosthetic heart valve on a distal end attached to a conduit graft that extends to a proximal end. The tool includes a proximal handle and a distal shaft, a prosthetic heart valve sizer having an axis affixed to a distal end of the shaft, and a conduit graft replica having an axis mounted on the shaft proximal to the heart valve sizer.
Edwards Lifesciences Corporation


Replacement heart valve with diaphragm
A replacement heart valve system may include a delivery sheath and a replacement heart valve. The replacement heart valve may include a mesh anchor member disposed within the delivery sheath in an elongated delivery configuration, the mesh anchor member being expandable to a deployed configuration when unconstrained by the delivery sheath.
Boston Scientific Scimed, Inc.


Low profile heart valve and delivery system
Apparatus for endovascularly replacing a patient's heart valve, including: a delivery catheter having a diameter of 21 french or less; an expandable anchor disposed within the delivery catheter; and a replacement valve disposed within the delivery catheter. The invention also includes a method for endovascularly replacing a heart valve of a patient.
Boston Scientific Scimed, Inc.


Everting heart valve
The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve.
Boston Scientific Scimed, Inc.


Self-actuating sealing portions for paravalvular leak protection
A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent having a proximal end and a distal end, and a valve assembly including a plurality of leaflets, the valve assembly being disposed within the stent. The heart valve further includes a first plurality of elongated legs coupled to the stent and transitionable from an extended configuration to a relaxed configuration.
St. Jude Medical, Cardiology Division, Inc.


Replacement valve and anchor

Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve.
Boston Scientific Scimed, Inc.

Replacement valve and anchor

Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve.
Boston Scientific Scimed, Inc.

Methods and apparatuses for deploying minimally-invasive heart valves

An assembly includes an expandable prosthetic heart valve, a catheter shaft, and a stabilization device. The expandable prosthetic heart valve has a valve body and a plurality of leaflets coupled to the valve body.
Edwards Lifesciences Corporation

Automatic extraction of disease-specific features from doppler images

An automatic extraction of disease-specific features from doppler images to help diagnose valvular diseases is provided. The method includes the steps of obtaining a raw doppler image from a series of images of an echocardiogram, isolating a region of interest from the raw doppler image, the region of interest including a doppler image and an ecg signal, and depicting at least one heart cycle, determining a velocity envelope of the doppler image in the region of interest, extracting the ecg signal to synchronize the ecg signal with the doppler age over the at least one heart cycle, within the region of interest, calculating a value of a clinical feature based on the extracted ecg signal synchronized with the velocity envelope, and comparing the value of the clinical feature with clinical guidelines associated with the clinical feature to determine a diagnosis of a disease..
International Business Machines Corporation

Detecting and suppressing noise signals of a differential voltage measuring system

Methods, noise detection devices, and differential voltage measuring systems are provided for detecting noise signals for the purpose of measuring cardiac movements in a patient. In the method, contact is made with the patient by at least two measuring electrodes having at least one associated measuring channel.

Physiological sensor delivery device and method

An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve.
Acist Medical Systems, Inc.

System and crossing a native heart valve with a guidewire

A system for crossing a heart valve with a guidewire includes an advancement motor and a controller. The controller controls when the advancement motor advances and retracts the guidewire.
Medtronic Vascular, Inc.

Heart valve sizing ring and method

A device for measuring heart valve for sizing a heart valve reinforcement ring, includes a handle having a first shaft and a second shaft; an inner ring coupled to the first shaft; an outer ring coupled to the second shaft; and a trigger mechanism configured and arranged to force the inner ring and outer ring together wherein an outer surface of the inner ring engages an inner surface of the outer ring; the inner surface of the outer ring and the outer surface of the inner ring having reciprocal mating surfaces configured and arranged to grip sutures therebetween when coupled together.. .

Apparatus and heart valve repair

A device and method for repairing a mitral valve leaflet 2, 3. The device 10 includes a body 16 having an annular wall 18 and at least one aperture 22 through the annular wall 18.
St. Jude Medical, Inc.

Device and delivery of an implant through a catheter

Disclosed herein is a delivery system for percutaneous heart valve repair, the delivery system including a steerable sheath configured to provide percutaneous access into a heart and to deliver an implant. The system may also have a steering mechanism configured to manipulate and orient the implant, a ball joint mechanism configured to connect the steerable sheath to the steering mechanism, a main knob assembly configured to advance and retract a multilumen shaft assembly, a stabilizing tool including a plurality of prongs configured to engage the implant within the heart to make an intimate contact with the heart tissue using a stabilizer and a tongue assembly, and a back assembly including: the actuation mechanism, a suture routing mechanism, a tip lock mechanism, and a back cover configured to protect all sutures being cut by mistake..
Valcare, Inc.

Stented prosthetic heart valve delivery system having an expandable bumper

Delivery devices for delivery of a stented prosthetic heart valve. Various delivery devices include an outer sheath assembly including an outer sheath connected to a capsule that is advanced proximally to retain the prosthetic valve, which is secured over an inner shaft assembly of the delivery device.
Medtronic Vascular, Inc.

Delivery system for a valve prosthesis

A heart valve prosthesis and delivery systems are provided for replacing a cardiac valve. The heart valve prosthesis includes a self-expanding frame includes a portion having a crimp that provides additional flexibility to the self-expanding frame in the collapsed configuration..
Medtronic, Inc.

Aortic leaflet repair using shock wave applicators

Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device may comprise an elongated flexible tube carried by a sheath.
Shockwave Medical, Inc.

Method for processing virtual machine cluster and computer system

The present disclosure provides a method for managing a virtual machine cluster. The method includes: sending, by the first virtual machine, a first heartbeat message to at least two neighboring virtual machines in the n virtual machines, so that the at least two neighboring virtual machines detect the first heartbeat message, where a result of detecting the first heartbeat message is used to determine a status of the first virtual machine, and the first virtual machine establishes a neighbor relationship with the at least two neighboring virtual machines according to the information about the n virtual machines; and detecting, by the first virtual machine as a neighboring virtual machine of a second virtual machine in the at least two virtual machines, a second heartbeat message sent by the second virtual machine..
Huawei Technologies Co., Ltd.

Heartbeat monitoring of virtual machines for initiating failover operations in a data storage management system, using ping monitoring of target virtual machines

An illustrative “vm heartbeat monitoring network” of heartbeat monitor nodes monitors target vms in a data storage management system. Accordingly, target vms are distributed and re-distributed among illustrative worker monitor nodes according to preferences in an illustrative vm distribution logic.
Commvault Systems, Inc.

Implementing automatic switchover

One or more techniques and/or computing devices are provided for automatic switchover implementation. For example, a first storage controller, of a first storage cluster, may have a disaster recovery relationship with a second storage controller of a second storage cluster.
Netapp Inc.

Heartbeat monitoring of virtual machines for initiating failover operations in a data storage management system, including operations by a master monitor node

An illustrative “vm heartbeat monitoring network” of heartbeat monitor nodes monitors target vms in a data storage management system. Accordingly, target vms are distributed and re-distributed among illustrative worker monitor nodes according to preferences in an illustrative vm distribution logic.
Commvault Systems, Inc.

Heartbeat monitoring of virtual machines for initiating failover operations in a data storage management system, including virtual machine distribution logic

An illustrative “vm heartbeat monitoring network” of heartbeat monitor nodes monitors target vms in a data storage management system. Accordingly, target vms are distributed and re-distributed among illustrative worker monitor nodes according to preferences in an illustrative vm distribution logic.
Commvault Systems, Inc.

Dynamic and adaptive approach for failure detection of node in a cluster

The present disclosure discloses a method and a network device for failure detection of nodes in a cluster. Specifically, a network device transmits data to another device at a first time.
Aruba Networks, Inc.

Cartridge and increasing myocardial function

The present invention relates to a cytopheretic cartridge for use in treating and/or preventing inflammatory conditions that affect myocardial function and to related methods. The cartridge can be used in treating a subject with myocardial dysfunction, such as a subject with chronic heart failure and/or acute decompensated heart failure..
Cytopherx, Inc.

Anatomic fit of a percutaneous vad for right heart support

An apparatus is disclosed including: a cannula having a shape closely matched to the anatomy of the right ventricle of the human heart, where the cannula has an outflow port configured to be located proximal the pulmonary artery and an inflow port located proximal the inferior vena cava. In some embodiments, the cannula is a close fit to the anatomy of at least 90%, 95%, or more of the population..
Abiomed, Inc.

Systems and methods for delivering and deploying an artificial heart valve within the mitral annulus

The present disclosure describes devices, systems, and methods for loading, delivering, positioning, and deploying an artificial heart valve device at the mitral annulus. A delivery system includes a delivery member coupled to a handle assembly and extending distally from the handle assembly.

Expandable valve prosthesis with sealing mechanism

A prosthetic heart valve includes at least one sealing member. The sealing member is adapted to conform to any surface irregularities found on the inner surface of the valve annulus, including any calcium deposits formed on the valve leaflets.
Mayo Foundation For Medical Education And Research

Prosthetic heart valve with cusp positioners

A prosthetic heart valve has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. A support frame including three cusp positioners is fixed with respect to a leaflet frame and located intermediate each pair of adjacent commissure regions.
Edwards Lifesciences Corporation

Method and monitoring heartbeats

A ballistocardiographic method and monitoring system calculates an indicator of the average heart rate of a test subject within a time interval. The test subject may be a fetus inside a mother's belly, or infant lying in the same bed as an adult.
Murata Manufacturing Co., Ltd.

Biological signal processing device and blood pressure measurement system

An r-wave of a heartbeat signal accompanied by periodic fluctuation is detected to obtain the average value of an rr interval. Further, a waveform of a heart sound signal, which periodically fluctuates in synchronization with the heartbeat signal, is forcibly repositioned at an interval equivalent to the average value of the rr interval.
Ai Technology Inc.

Signal continuity assessment using embedded watermarks

Methods, apparatus, and systems use embedded watermarks to determine whether the segments of a multimedia content has been rearranged. The embedded watermarks are recovered from the content and one or more attributes associated with the recovered watermarks are identified.
Verance Corporation

Heartbeats and consensus in verifiable outsourced ledgers

Heartbeat consensus forming for the state of a digital ledger built upon a blockchain to provide users with the ability to securely, accurately, and verifiably share state information between distrustful parties is provided herein. The digital ledger is hosted in a networked environment, accessible by multiple parties.
Microsoft Technology Licensing, Llc.

Platform communication protocol

A host chipset heartbeat may be utilized, in some embodiments, to handle interrupts from external devices on a power efficient basis. The availability of the host chipset heartbeat may be signaled to external devices and those external devices may time their activities to a period of time when not only are resources available, but the assertion of the activity is advantageous because the host chipset is already transitioning from a lower power consumption state..
Intel Corporation

Transapical mitral valve replacement

A prosthetic heart valve includes a collapsible and expandable stent having an outflow end and an inflow end, a plurality of commissure features attached to the stent, a plurality of anchoring features disposed on legs of the stent, the plurality of anchoring features being coupleable to a delivery device for repositioning, and a valve assembly disposed within the stent. The anchoring features may be configured to attach to heart tissue to help secure the prosthetic heart valve in an operating position..
St. Jude Medical, Cardiology Division, Inc.

Valve replacement using rotational anchors

Features for a heart valve device are described. The device may include a frame with anchors configured to secure the device to tissue.
Millipede, Inc.

Prosthetic valve and deployment system

A prosthetic heart valve, for example a tricuspid valve, may include a flexible membrane and a frame. The frame may be attached to the periphery of the tricuspid orifice.
Trisol Medical Ltd.

Buckle pad

A replacement heart valve implant may include an expandable anchor member actuatable between a delivery configuration and a deployed configuration, a plurality of locking mechanisms configured to maintain the expandable anchor member in the deployed configuration, one or more valve leaflets attached to each of the plurality of locking mechanisms, and at least one polymeric laminate corresponding to each locking mechanism, each of the at least one polymeric laminate sized and configured for mounting between a first portion of the corresponding locking mechanism and the expandable anchor member.. .
Boston Scientific Scimed, Inc.

Method and device for processing bio-signals

A method for computing the heart rate value of an user, including detecting a time-dependent optical waveform including a pulse induced by the heartbeat with an optical pulse sensor attached to the user, detecting of a time-dependent accelerometer waveform by an inertial sensor arranged in proximity of the optical pulse sensor, computing of frequency components of the time-dependent optical waveform by a mathematical transform, computing of frequency components of the time-dependent accelerometer waveform by the mathematical transform, first removing of computed frequency components of the time-dependent accelerometer waveform that are below a pre-defined threshold, second removing the computed frequency components of the time-dependent optical waveform that are matching the computed frequency components, third removing the computed frequency components after the second removing that are below a pre-defined threshold, and choosing one of the computed frequency components from the third removing as the heart rate.. .
Smartcardia Sa

Apparatus and determining bio-information of target using impulse radar

An apparatus and method for determining bio-information of a target using an impulse radar are provided. The method may include generating a frame set by accumulating frames received at preset time intervals, determining a first magnitude spectrum of the frame set corresponding to a first frequency axis by performing a frequency conversion of frames included in the frame set in a sampler index axis direction, determining a second magnitude spectrum of the frame set corresponding to the first frequency axis and a second frequency axis by performing a frequency conversion of the first magnitude spectrum in a time axis direction, determining a third magnitude spectrum of the frame set by adding up values of the second magnitude spectrum for each second frequency, and determining a frequency indicating a peak in the third magnitude spectrum as a heartbeat frequency of the target..
Daegu Gyeongbuk Institute Of Science And Technology

Magnetic resonance imaging apparatus and magnetic resonance imaging method

A magnetic resonance imaging apparatus according to an embodiment includes processing circuitry and sequence control circuitry. The processing circuitry sets a pattern based on information on heartbeats or pulsebeats of a subject, the pattern being an imaging condition of a pulse sequence for collecting data at a plurality of timings along a relaxation curve of longitudinal magnetization in synchronization with heartbeats or pulsebeats and the pattern defining a relation between heartbeats or pulsebeats, an inversion pulse, and a data collection timing.
Toshiba Medical Systems Corporation

Internet-of-things-based safety system

Building safety system architecture, methods, and mediums. A method includes receiving substantially-continuous heartbeat communications from a plurality of safety control devices over a packet data network.
Siemens Industry, Inc.

Methods for detecting an increased risk for coronary heart disease

The invention relates generally to an allele on human chromosome 9 associated with increased risk for coronary heart disease and the use or detection of such an allele in determining whether a human has an increased risk for coronary heart disease. In one aspect, the invention relates to methods for detecting a predisposition or propensity or susceptibility for coronary heart disease in a human, comprising detecting the presence of an allele on human chromosome 9 that is associated with an increased risk for coronary heart disease in a human.
Board Of Regents, The University Of Texas System

Treadmill and monitoring system

A monitoring and computing system for use with a treadmill, includes an intelligent sensing and computing system includes the data collection box and the sensors. The sensors includes the infrared sensor for sensing the speed, the six axes sensor for sensing the slope and the step frequency, the electrocardiogram sensor for sensing the heartbeat.
Foxconn Interconnect Technology Limited

Prosthetic device for heart valve reinforcement and remodeling procedures

A prosthetic heart valve reinforcement ring is disclosed for reinforcing a natural heart valve with leaflets. The prosthetic ring includes a ring body sized and dimensioned to fit around the annulus of the heart valve.

Devices and methods for transcatheter heart valve delivery

A delivery device for a collapsible prosthetic heart valve includes an operating handle and a catheter assembly. The operating handle may include a housing defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, a deployment actuator coupled to the housing and rotatable relative to the housing, and a coupling assembly rotationally fixed to the deployment actuator.
St. Jude Medical, Cardiology Division, Inc.

Prosthetic heart valve with reduced stitching

An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, and a skirt member secured to the frame. The skirt member includes a plurality of extension portions wrapped around at least one strut member adjacent the extension portions.
Edwards Lifesciences Corporation

Prosthetic heart valve

A prosthetic heart valve includes a valve frame (2), on which a plurality of valve leaflets (8) are fixed, and a fastening area for fastening in a blood vessel, which axially adjoins the valve frame (2). A stabilizing ring (14) is arranged in the fastening area.

Valved stent for mitral and tricuspid heart valve replacement

An implantable valved stent for a patient's heart is formed by a stent supporting a cloth structure. The valved stent includes an upper mounting portion and a lower valved portion.
Peijia Medical Co., Ltd.

Heart valve prosthesis

A heart valve prosthesis includes a downstream first axial end (6) and an upstream second axial end (8) and a stitching ring (10) extending in an arcuate manner for stitching in a blood vessel. The arcuate course of the stitching ring (10) is formed by three arcs (12) and three transition regions (14).

Device and improving heart valve function

The invention is a method for reducing regurgitation through a mitral valve. The device and method is directed to an anchor portion for engagement with the heart wall and an expandable valve portion configured for deployment between the mitral valve leaflets.
Edwards Lifesciences Ag

Assistive device for a cardiac valve

A device for reducing heart valve regurgitation including a plug for placing between natural heart valve leaflets, the plug shaped so that, upon systole, the natural heart leaflets coapt upon the plug, a frame attached to the plug by a bridging element, for supporting the plug between the natural heart valve leaflets, the frame having at least one dimension in a plane of the heart valve annulus which is wider than the diameter of the heart valve annulus, and a plurality of anchors attached to the device, for preventing the device from being swept upstream of the heart valve annulus upon systole. Related apparatus and methods are also described..
Mitrassist Medical Ltd.

Method and monitoring an organ of a patient

An apparatus for determining tissue versus fluid components of an organ include a detector that generates a detector signal based on electrical signals derived from tissue and fluid. The apparatus includes a signal processor in communication with the detector which subtracts in real time a tissue component from the detector signal and produces a fluid volume signal.
Board Of Regents, The University Of Texas System

Processing timestamps and heartbeat events for automatic time progression

An event processing system for processing events in an event stream is disclosed. The system is configured for configuring a stream processor to micro-batch incoming events from a stream source.
Oracle International Corporation

Methods and compositions for enhancing cardiac contractility for treatment of heart failure

The invention provides a therapeutically-effective method for treatment of heart failure (hf), chronic heart failure, and heart failure post myocardial infarction (mi). This method treats heart failure by enhancing cardiac contractility in a patient by activating β-arrestin 2 to enhance sarco(endo) plasmic reticulum ca−2 atpase (serca-2a) small ubiquitin-like modifier-ylation (sumolation).
Nova Southeastern University

Herbal supplement ''optimal cholesterol''

“optimal cholesterol” utilizes edible nature plant extracted by a variety of technology, it is one of the nature plant medicines which can treat atherosclerotic coronary heart disease, cerebral vascular disease and systemic vascular disease in the world. Its function is to soften the arterial blood vessels, and to treat arteriosclerosis, protect and repair the vascular endothelial cells; soft plaque, fibrous plaque and calcified plaque are removed during the process of preventing plaque rupture, bleeding, erosion and ulcer; regulate micro-circulation, enhance the ability of coronary artery blood supply, adjust heart rate, furthermore, there's none toxic side effects after long-term use..

Methods and materials for treating calcific aortic valve stenosis

This document provides methods and materials involved in treating cardiovascular conditions such as calcific aortic valve stenosis. For example, methods and materials for using sgc agonists or a combination of sgc agonists and pde5a inhibitors to reduce calcification of heart valves and/or vessels or to slow progression of aortic sclerosis to calcific aortic valve stenosis are provided..
Mayo Foundation For Medical Education And Research

Steerable lesion excluding heart implants for congestive heart failure

Devices, systems, and methods for treating a heart of a patient may make use of one or more implant structures which limit a size of a chamber of the heart, such as by deploying a tensile member to bring a wall of the heart toward (optionally into contact with) a septum of the heart.. .
Bioventrix, Inc.

Apparatuses and methods for at least partially supporting a valve leaflet of a regurgitant heart valve

An apparatus for partially supporting a leaflet of a regurgitant heart valve comprises at least one subvalvular device including a subvalvular supporting portion including a leaflet-contacting upper supporter surface longitudinally spaced from an oppositely facing lower supporter surface. A supporter perimeter wall extends longitudinally between the upper and lower supporter surfaces, with at least a portion contacting a subvalvular cardiac wall adjacent to the heart valve.

Assembly for replacing a heart valve or coronary angioplasty assembly including a delivery catheter with or without introducer

The present invention relates to an assembly for replacing a heart valve or coronary angioplasty assembly, including an insertion sheath (13) of an introducer (1) or a delivery catheter (1′), which is smaller in size than an introducer, intended for being inserted into an artery of a human body. The invention essentially involves integrating the metal substrate of an electrode of the cardiac stimulator directly into the sheath for insertion into the artery of a patient..

Stent cell bridge for cuff attachment

A prosthetic heart valve includes a collapsible stent extending from an inflow end to an outflow end, and a cuff having an inflow end an outflow end. The stent includes first and second circumferential rows of cells defined by first and second pluralities of struts, respectively.
St. Jude Medical, Cardiology Division, Inc.

Prosthetic heart valve with paravalvular leak mitigation features

A prosthetic heart valve includes a collapsible and expandable stent with a valve assembly disposed therein. A first cuff is positioned on the lumenal or ablumenal surface of the stent.
St. Jude Medical, Cardiology Division, Inc.

Multiple aperture sling for mitral heart valves

A sling with multiple openings may be installed in a mitral valve annulus. Within each opening, individual valves may be placed.
Infinity Patent Holdco Llc

Heart valve pinch devices and delivery systems

Pinch devices and access systems that can be used to secure a prosthetic heart valve to a heart valve annulus and to treat valvular insufficiency. A pinch device can be a separate expandable element from the prosthetic heart valve that is first advanced to the annulus and deployed, after which an expandable prosthetic heart valve can be advanced to within the annulus and deployed.
Edwards Lifesciences Corporaton

Systems, devices, and methods for performing trans-abdominal fetal oximetry and/or trans-abdominal fetal pulse oximetry using a fetal heartbeat signal

Light reflected from a pregnant woman's abdomen and fetus contained therein that has been received by a detector and converted into a reflected electronic signal may be received by a processor. A portion of the reflected electronic signal that is reflected from the fetus may be isolated and the isolated portion of the reflected electronic signal may be analyzed to determine a fetal hemoglobin oxygen saturation level of the fetus.
Raydiant Oximetry, Inc.

Method and determining cardiac performance in a patient with a conductance catheter

An apparatus for determining cardiac performance in the patient includes a plurality of electrodes adapted to be placed in the patient and in communication with a heart chamber of the patient for measuring conductance and blood volume in the heart chamber of the patient; and a processor for determining instantaneous volume of the ventricle based on measurement of complex admittance at a plurality of frequencies to identify mechanical strength of the chamber, the processor in communication with the electrodes. A method for determining cardiac performance in a patient..
Board Of Regents, The University Of Texas System

User identification via motion and heartbeat waveform data

The disclosure relates to methods, devices, and systems to identify a user of a wearable fitness monitor using data obtained using the wearable fitness monitor. Data obtained from motion sensors of the wearable fitness monitor and data obtained from heartbeat waveform sensors of the wearable fitness monitor may be used to identify the user..
Fitbit, Inc.

Isolation of pulmonary arterial endothelial cells from patients with pulmonary vascular disease and uses thereof

The present disclosure provides methods of obtaining, recovering and culturing pulmonary arterial endothelial cells from an individual patient subjected to a right heart catheterization in regard to diagnosis of pulmonary hypertension. These isolated pulmonary arterial endothelial cells from an individual patient may be utilized to generate cellular phenotyping profile for the cell population, allowing generation of a personalized pharmacotherapy regime to assist the clinician in treatment and prognosis of the disorder for an individual patient..
Allegheny-singer Research Institute

Bioelectric stimulator

Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment.
Cal-x Stars Business Accelerator, Inc.

Apparatus and heart valve repair

A device 10 for gathering tissue of a heart valve leaflet 2 may include an outer tube 16 extending in an elongation direction, a capture tool 22 moveable in the outer tube between a contained position and a use position, and a tissue securing component 32 disposed at a distal end 17 of the outer tube and adapted to be applied to tissue 8 captured by the capture tool to hold the captured tissue in a gathered configuration. The capture tool may include a first element 20 and a second element 22 that are moveable relative to one another in the elongation direction.
St. Jude Medical, Llc

Sleep stage estimating apparatus, biological data estimating apparatus, sleep stage estimating method, biological data estimating method, sleep stage estimating program, and biological data estimating program

The estimation of the sleep stage at a time point where data does not exist, is enabled. An acquiring unit configured to acquire biological data indicating a wave of a heartbeat; a parameter estimating unit configured to estimate a parameter by using the biological data, with respect to a mathematical expression defining a medium frequency component of the wave of the heartbeat by using the parameter; and a sleep stage estimating unit configured to estimate a sleep stage from a value of the medium frequency component at any time point, based on the mathematical expression to which the estimated parameter is applied, are included..
The University Of Electro-communications

Sleepiness calculation device

A sleepiness calculation device is provided. In a smartphone, i/f obtains heart rate of the subject measured by a heartbeat sensor and measurement time, determines active state of a subject in the state discriminant section, and send it to a server.
Pioneer Corporation

Method, device and system for amending heartbeat type

The present disclosure relates to a method, device and system for amending a heartbeat type. The method includes: displaying an interface for presenting heartbeat waveforms; based on a user interface provided on the interface for presenting the heartbeat waveforms, detecting a currently triggered heartbeat type; and when detecting that at least one electrocardiogram waveform on the interface for presenting the heartbeat waveforms is selected, amending a heartbeat type of the selected at least one electrocardiogram waveform as the currently triggered heartbeat type.
Edan Instruments, Inc.

Transcatheter guidewire delivery systems, catheter assemblies for guidewire delivery, and methods for percutaneous guidewire delivery across heart valves

Transcatheter guidewire delivery systems, catheter assemblies and associated methods for percutaneous guidewire delivery across heart valves are disclosed herein. A catheter assembly configured in accordance herewith includes an elongated tubular component and an alignment assembly at a distal portion of the tubular component and which is adapted to be located at a target location adjacent a heart valve of a patient.
Medtronic Vascular, Inc.

Transcatheter guidewire delivery systems, catheter assemblies for guidewire delivery, and methods for percutaneous guidewire delivery across heart valves

Transcatheter guidewire delivery systems, catheter assemblies and associated methods for percutaneous guidewire delivery across heart valves are disclosed herein. A catheter assembly configured in accordance herewith includes an elongated tubular component and an alignment assembly at a distal portion of the tubular component and which is adapted to be located at a target location adjacent a heart valve of a patient.
Medtronic Vascular, Inc.

Repositionable endoluminal support structure and its applications

A prosthetic heart valve includes a frame, a valve component, and a skirt. The frame has first and second end portions, a central longitudinal axis extending between the first and second end portions, and a plurality of struts interconnected by a plurality of joints.
Edwards Lifesciences Cardiaq Llc

Heart valve prosthesis and separate support flange for attachment thereto

A valve prosthesis assembly for implantation into a native valve site. The valve prosthesis assembly includes a valve prosthesis with a prosthetic valve component and a frame.
Medtronic Vascular, Inc.

Prosthetic heart valve devices and methods of valve replacement

A stented valve having at least one leaflet made of pericardium or other material having a relatively thin profile at the annulus. The leaflets are attached via chords to a stent frame, where the chords are positioned to mimic the native valve anatomy and functionality.
Medtronic, Inc.

Prosthetic heart valve with paravalvular leak mitigation features

A prosthetic heart valve includes a collapsible stent and a valve assembly disposed within the stent. A first cuff is disposed adjacent the stent.
St. Jude Medical, Cardiology Division, Inc.

Heart valve docking system

Docking devices can be configured to be positioned at a native valve of a human heart to provide structural support for docking a prosthetic valve. The docking devices generally have coiled structures that define an inner space in which the prosthetic valve can be held.
Edwards Lifesciences Corporation

Multi-portion replacement heart valve prosthesis

A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame.
Edwards Lifesciences Corporation

Heart valve docking coils and systems

Anchoring or docking devices configured to be positioned at a native valve of a human heart and to provide structural support for docking a prosthetic valve therein. The docking devices can have coiled structures that define an inner space in which the prosthetic valve can be held.
Edwards Lifesciences Corporation

Perivalvular occlusion device and methods

An occlusion device intended for blocking perivalvular leak channels that are found following heart valve implantation between the heart valve and the surrounding tissue. The occlusion device has a stent and a covering that is attached to the stent surface.

Apparatus and intra-cardiac mapping and ablation

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a maze procedure.
Kardium Inc.

Transcatheter aortic valve implantation assembly with integrated imager

A transcatheter aortic valve implantation (tavi) delivery system includes a sheath, a replacement valve assembly disposed within a distal end of the sheath, and a nose cone proximate the distal end of the sheath. A forward section of the nose cone is configured to facilitate passage of the nose cone through the heart valve.
Tyco Electronics Corporation

System and detecting active streams using a heartbeat and secure stop mechanism

One embodiment of the present invention sets forth a technique for identifying active streaming connections associated with a particular user account. Each active streaming connection transmits heartbeat packets periodically to a server that tracks the receipt of the heartbeat packets.
Netflix, Inc.

Vehicle occupant detection system

A living vehicle occupant detection system has a control unit that is mounted within a vehicle, a temperature sensor which is mounted within the interior passenger compartment of the vehicle and is communicatively coupled (either wired or wirelessly) to the control unit, and a life detection unit that will indicate the presence and location of a heartbeat within the interior of the vehicle and that is communicatively coupled (either wired or wirelessly) to the control unit. A carbon monoxide (co) sensor may also be installed within the interior of the vehicle to optimize co detection and is coupled (either wired or wirelessly) to the control unit..

Sizing device and positioning a prosthetic heart valve

A sizing device for a collapsible prosthetic heart valve includes a collapsible and expandable stent. The stent has an annulus section at a first end with a first diameter and an aortic section at a second end with a second diameter.
St. Jude Medical, Cardiology Division, Inc.

Heart valve regurgitation anchor and delivery tool

A heart valve anchor apparatus may include a body having a proximal portion and a distal portion. The body may include a first radially expandable portion at the proximal portion of the body, a second radially expandable portion at the distal portion of the body, and a root portion extending from the first radially expandable portion to the second radially expandable portion, the root portion having an outer extent.
Mayo Foundation For Medical Education And Research

Prosthetic heart valve with retention elements

Described embodiments are directed toward centrally-opening leaflet prosthetic valve devices having a leaflet frame and a leaflet construct. The leaflet construct is at least partially coupled to a leaflet frame outer side of the leaflet frame and being coupled thereto by a retention element..
W. L. Gore & Associates, Inc.

Prosthetic heart valve formation

A prosthetic heart valve includes a base and a plurality of polymeric leaflets. Each leaflet has a root portion coupled to the base, and each leaflet has an edge portion substantially opposite the root portion and movable relative to the root portion to coapt with a respective edge portion of at least one of the other leaflets of the plurality of leaflets.
Boston Scientific Scimed, Inc.

Transcatheter valve replacement

A prosthetic heart valve having an inflow end and an outflow end includes a collapsible and expandable stent, a collapsible and expandable valve assembly disposed within the stent and having a plurality of leaflets, and a deformable frame having a first end and a second end. The frame includes braided wires forming a body having a lumen extending therethrough for receiving the stent and the valve assembly, the body having a plurality of diameters from the first end to the second end..
St. Jude Medical, Cardiology Division, Inc.

Ultrasonic diagnosis of cardiac performance by single degree of freedom chamber segmentation

An ultrasonic diagnostic imaging system has a user control by which a user positions the user's selection of a heart chamber border in relation to two machine-drawn heart chamber tracings. The user's border is positioned by a single degree of freedom control which positions the border as a function of a single user-determined value.
Koninklijke Philips N.v.

Heartbeat detecting device and biological signal processing device

The difference between the current value and the last value of an rr interval is compared with a predetermined reference differential value, and an attenuation time constant of a peak-hold section is controlled according to the comparison result.. .
Ai Technology Inc.

Weight scale and corresponding preventing advancement of congestive heart failure

A weight scale (100) for assisting with management of congestive heart failure and other ailments includes a housing (101) that can define a substantially flat planar surface (102). A weight measurement device (202) measures a weight of a user.
Medline Industries, Inc.

Mesh enclosed tissue constructs

A heart valve leaflet including a thermoplastic polyurethane (tpu) mesh material that has a stiffness that is comparable to a native heart valve leaflet, such that it functionally mimics a native heart valve leaflet. The heart valve leaflets optionally include one to three layers of cells cultured on each side of the mesh material.
The Regents Of The University Of California

Novel methods

Provided are uses of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the treatment or prophylaxis of transplant rejection and the protection of the heart during heart surgery. Provided is the use of selective aquaporin inhibitors, e.g., of aquaporin-4 (aqp4) or aquaporin-2 (aqp2) for the treatment or prophylaxis of transplant rejection and for the protection of the heart during heart surgery..
Aeromics, Inc.

Devices and methods for the treatment of heart valve insufficiencies

Disclosed herein are various embodiments directed to a device for minimally invasive medical treatment. The device being a hollow tube with a first end, a second end, and one or more anchors configured to extend outward from the exterior of the hollow tube.
Valcare, Inc.

Collapsible cardiac implant and deployment system

A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site.
Edwards Lifesciences Corporation

Heart chamber prosthetic valve implant with elevated valve section and single chamber anchoring for preservation, supplementation and/or replacement of native valve function

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device with an elevated valve section and comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed..
4c Medical Technologies, Inc.

Heart chamber prosthetic valve implant with base, spring and dome sections with single chamber anchoring for preservation, supplementation and/or replacement of native valve function

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed..
4c Medical Technologies, Inc.

Heart chamber prosthetic valve implant with base, mesh and dome sections with single chamber anchoring for preservation, supplementation and/or replacement of native valve function

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed..
4c Medical Technologies, Inc.

Two stage cellularization strategy for the fabrication of bioartificial hearts

In some embodiments, the present disclosure pertains to a method of fabricating an artificial heart muscle (ahm) patch. In some embodiments, the method comprises obtaining and/or isolating cells from a subject.
University Of Houston System

Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage

A packaged bioprosthetic heart valve comprising a bioprosthetic heart valve, an adaptive seal and a package. The bioprosthetic heart valve comprises an at least partially dehydrated biological tissue leaflet structure coupled to a supporting frame.
Edwards Lifesciences Corporation

Apparatus and intra-cardiac mapping and ablation

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a maze procedure.
Kardium Inc.

Dual energy x-ray coronary calcium grading

Methods and apparatus for grading coronary calcium, including an example apparatus that includes a set of logics and a memory that stores a set of radiographic images. The set of logics includes an image acquisition logic that acquires a set of radiographic images of a region of tissue, the set of radiographic images including a low-energy reference x-ray image and a higher-energy floating x-ray image, a registration logic that produces a set of registered images from a plurality of members of the set of radiographic images, an enhancement logic that produces a set of calcium-enhanced images from the set of registered images, a post-enhancement logic that produces a bone image from the set of calcium-enhanced images, and a grading logic that computes a coronary heart disease prediction score based, at least in part, on the bone image and a set of features extracted from the bone image..
Case Western Reserve University

Sensors for prosthetic heart devices

Prosthetic heart devices may be implanted into the heart with a sensor coupled to the device, the sensor being configured to measure physiological data, such as blood pressure, in the heart. Devices that may employ such sensors include prosthetic heart valves and occlusion devices, although sensor systems may be deployed in the heart separate from other implantable devices.
St. Jude Medical, Cardiology Division, Inc.

Identifying ecg signals having the same morphology

A method, including selecting an initial set of electrocardiograph (ecg) signals taken over a single heartbeat of a human subject, the set having respective morphologies to be used as a template for an arrhythmia of the subject, and receiving a subsequent set of ecg signals taken over a subsequent heartbeat of the human subject. The method also includes performing a cross-correlation between the initial set and the subsequent set, so as to generate a correlation coefficient that is a measure of a goodness of fit between geometries of the initial set and the subsequent set, and, when the correlation coefficient exceeds a threshold coefficient, accepting the subsequent heartbeat as having been caused by the arrhythmia..
Biosense Webster (israel) Ltd.

Realtime feedback response system and methods of using the same

Provided herein are apparatus and methods of relaxation. In particular, disclosed herein includes a system that provides realtime or near realtime feedback response to a user in order to achieve a relaxation response.

Systems and methods for treating pulmonary hypertension

A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit.
Aria Cv, Inc.

Devices for remodeling a valve annulus and ventricle

Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member..
Edwards Lifesciences Corporation

Delivery system with inline sheath

Systems and methods for delivering and implanting heart valves are disclosed. The delivery systems can include an integrated introducer.
Medtronic, Inc.

Delivery systems for prosthetic heart valve

A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion.
Edwards Lifesciences Corporation

Delivery devices for implantable medical devices and methods of manufacturing same

This disclosure describes, among other things, methods, devices, and systems for non-invasive evaluation of a patient's vascular system and custom design and manufacture of one or more components of a delivery device for delivery and deployment of an implantable medical device, such as a prosthetic heart valve. For example, a delivery sheath can be 3d printed to have varying durometers at one or more areas along its length and/or circumference so that it can more easily bend and flex as it traverses particularly tortuous anatomical features..
Medtronic Vascular, Inc.

Valve leaflet attachment in collapsible prosthetic valves

A prosthetic heart valve includes a stent having a collapsed condition and an expanded condition. The stent includes a plurality of cells, each cell being formed by a plurality of struts, and a plurality of commissure features.
St. Jude Medical, Cardiology Division, Inc.

Prosthetic heart valve using pericardium and manufacturing same

A prosthetic heart valve using a pericardium is disclosed where: three hetero-biological tissue slices, which are extracted in a quadrangular shape from a bovine pericardium or a porcine pericardium, are prepared; each hetero-biological tissue slice is folded so as to form an inner tissue slice inside and an outer tissue slice outside, the outer tissue slice being longer than the inner tissue slice; each of the inner tissue slice and outer tissue slice is coupled by sewing in a semicircular shape with a first coupling thread such that each inner tissue slice forms a pulmonic valve slice inside the first coupling thread and a fixing slice outside the first coupling thread such that each hetero-biological tissue slice is formed in a cylindrical shape by allowing each slice to be adjacent to each other. The disclosed prosthetic heart valve has increased durability and prevents reverse blood flow..
Taewoong Medical Co., Ltd.

Methods and apparatuses for remodeling tissue of or adjacent to a body passage

Medical devices and methods for making and using the same are disclosed. An example method may include a method for treating a patient having congestive heart failure.
Vessix Vascular, Inc.

System and non-invasive measurement of pressure inside a body including intravascular blood pressure

A device system and method for the non-invasive ultrasound measurement of the intravascular blood pressure is presented, wherein the blood pressure measurements are performed by means of the registration of the distances changes between the surface of the active piezoelectric transducer radiating an ultrasound beam into the localization area of the blood vessel or the heart chamber and the surface elements of the passive ultrasound beam reflector implanted into the blood vessel or the heart chamber. The invention is applicable to any medium transparent for ultrasound waves with the need to measure pressure changes of the liquid..
Pi-harvest Holding Ag

Automatic heart rate diagnostics

In some examples, processing circuitry of a medical device system determines, for each of a plurality of periods, a plurality of heart rates of a patient based on a cardiac electrogram signal, and identifies a first subset of the plurality of heart rates as nighttime heart rates and a second subset of the plurality of heart rates as resting heart rates. The processing circuitry determines a representative nighttime heart rate based on the first subset of the plurality of heart rates, determines a representative resting heart rate based on the second subset of the plurality of heart rates, and determines a nocturnal dip base on the representative nighttime heart rate and the representative resting heart rate.
Medtronic, Inc.

Introduced to electromedical equipment for automated triage of newborn with possible congenital heart defects

The present patent refers to improvements introduced in electromedical equipment, applied to automated triage of newborn babies with purpose to detect possible congenital heart defects by means of little heart test, through dedicated software (ds) implanted in memory (1-g), georeference block (1-m), pendrive (3), external hd (4), energy and supply assembly (e) provided with dc02215v j4 connector, cable and power supply, plug (p) positioned at the rear panel of the apparatus (1), internal and external connections (c) with magnets arranged into two rows at the rear part of the apparatus (1), of “c”-shape metallic base (2) with two front flanges (2-a), aiming to increase the number of users, increase flexibility of test protocol and change the usability in order to minimize errors, bringing advantages of higher testing speed, improved interface with user, better measurement quality, lower cost, higher usage versatility, and lighter weight and smaller size of equipment.. .
Hi Technologies Sa

Lockstep networking

Exemplary methods, apparatuses, and systems configure a recurring heartbeat for a first field device to operate in synchronization with a second field device and a base station. The first field device turns off radio power for a hibernation period.
Gthrive, Inc

Real-time user authentication using integrated biometric sensor

A computing device includes a housing, a processor, memory, a human interface device (i.e., a keyboard or a trackpad), and a biometric sensor integrated into the housing. The biometric sensor is configured for capturing biometric data (i.e., heartbeat data or a vein scan) from one or more of hands of a user of the device while the user's fingers are interacting with the human interface device.
Google Inc.

Vagus nerve and carotid baroreceptor stimulation system

Systems and methods are provided for delivering vagus nerve stimulation and carotid baroreceptor stimulation to patients for treating chronic heart failure and hypertension. The vagus nerve stimulation and carotid baroreceptor stimulation therapies may be provided using a single implantable pulse generator, which can coordinate delivery of the therapies..
Cyberonics, Inc.

Biological valve for venous insufficiency

A bioprosthetic valve for repairing a deep venous insufficiency in a subject includes a single leaflet from a xenogeneic heart valve attached at natural margins of attachment to a patch of valve wall tissue. The patch may extend axially above and below the leaflet and circumferentially on either side of the leaflet to provide a region for attaching the patch to a fenestration in a host vein.
Hancock Jaffe Laboratories, Inc.

Treatment of cardiac remodeling and other heart conditions

The present disclosure provides novel methods for treating cardiac remodeling and heart conditions using specific compounds, as well as compositions, and pharmaceutical formulations. In some embodiments, the compounds may inhibit acetylation of mef2 transcription factors..
University Of Miami

Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves

Apparatus and methods are described herein for use in the delivery and deployment of a prosthetic mitral valve into a heart. In some embodiments, an apparatus includes a catheter assembly, a valve holding tube and a handle assembly.
Tendyne Holdings, Inc.

Retaining mechanisms for prosthetic valves

Prosthetic valve systems for replacing a native valve exhibiting regurgitation comprises a support structure and a transcatheter heart valve (thv) that is separate from the support structure. The support structure can be configured to be positioned such that it extends annularly around the native valve leaflets.
Edwards Lifesciences Corporation

Prosthetic heart valve

A prosthetic heart valve can include a radially collapsible and expandable annular frame having a plurality of struts defining openings. The prosthetic heart valve can further include a plurality of leaflets that regulate the flow of blood through the frame.
Edwards Lifesciences Corporation

Retaining mechanisms for prosthetic valves

Disclosed herein are representative embodiments of methods, apparatus, and systems used to deliver a prosthetic heart valve to a deficient valve. In one embodiment, for instance, a support member is positioned to at least partially surround the native leaflets of a valve.
Edwards Lifesciences Corporation

Apparatuses and methods for cutting a tissue bridge and/or removing a heart valve clip or suture

Disclosed is an instrument having an elongated shaft, a first member configured in the elongated shaft such that the first member can be deployed from a first portion of the instrument. The first member, when deployed, is configured over a tissue bridge within a heart, the tissue bridge having a clip or suture.
Mitracore Technologies Inc.

Drowsiness detection program medium, drowsiness detection method, and drowsiness detection apparatus

A drowsiness detection method that causes a computer to execute a process, the process includes: performing frequency analysis on heartbeat data obtained from a subject; and determining a state of the subject by calculating entropy in a predetermined frequency bandwidth with a peak as a reference, where the peak is within a predetermined frequency range of frequency distribution obtained from the frequency analysis result, determining that the subject is in a relaxation state in a case where the calculated entropy is less than a predetermined threshold value, and determining that the subject is in a drowsiness state in a case where the entropy is equal to or greater than the threshold value.. .
Fujitsu Limited

File transmission method, apparatus, and distributed cluster file system

A file transmission method includes: obtaining file information of a to-be-transmitted file from a distributed coordination node cluster; determining that at least one slave push node stores the to-be-transmitted file according to the file information of the to-be-transmitted file and heartbeat information of the at least one slave push node; wherein the heartbeat information of the at least one slave push node contains file information stored in the at least one slave push node, and the to-be-transmitted file is retrieved by the at least one slave push node from a file storage node cluster; generating a file transmission path, wherein the file transmission path comprises at least one destination node cluster; sending the file transmission path to the at least one slave push node, so that the at least one slave push node sends the to-be-transmitted file to the at least one destination node cluster through the file transmission path.. .
Tencent Technology (shenzhen) Company Limited

Monitoring of replicated data instances

Replicated instances in a distributed computing environment provide for automatic failover and recovery. A component monitors the status of event processors in a set or bucket and handles the failure of an event processor.
Amazon Technologies, Inc.

Catheter system for implantation of prosthetic heart valves

The invention relates to a catheter for the transvascular implantation of prosthetic heart valves, in particular comprising self-expanding anchorage supports (10), which allow a minimally invasive implantation of prosthetic heart valves. The aim of the invention is to reduce the risk to the patient during the implantation.
Jenavalve Technology, Inc.

Heart valve assembly

A heart valve assembly has a heart valve assembly that has a wire frame comprising an anchor section, a generally cylindrical valve support section, and a neck section that transitions between the anchor section and the valve support section. The wire frame includes a plurality of supports extending radially outwardly in an annular manner about an upper end of the valve support section, and the anchor section has an annular flange that extends radially therefrom, so that an annular space is defined between the annular flange and the annular supports for receiving or capturing the native annulus when the heart valve is deployed.
Venus Medtech (hangzhou) Inc.

Replacement heart valve prosthesis

A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body.
Edwards Lifesciences Corporation

Methods for improved prosthetic heart valve with leaflet shelving

Described embodiments are directed toward prosthetic valve leaflets of particular configurations that control bending character. In embodiments provided herein, valve leaflets are operable to bend along a base of the valve leaflets..
W. L. Gore & Associates, Inc.

Prosthetic heart valve having improved commissure supports

A prosthetic heart valve can comprise a radially collapsible and expandable annular frame and a leaflet structure comprising a plurality of leaflets mounted within the frame. The frame can have commissure attachment portions that are configured to support the commissures of the leaflets in unique ways.
Edwards Lifesciences Corporation

Indication of risk for coronary artery disease

A way of indicating a risk for coronary artery disease is disclosed. A first plurality of first sound recordings of heartbeats and second plurality of second sound recording of the ambient background are obtained.
Acarix As

Method of monitoring health while using a toilet

A method of obtaining health data of a toilet user using one or more sensors is disclosed. One or more sensors are used by a toilet user while the toilet user is using the toilet to take health measurement readings of the user.

Polyurethanes

Partially crosslinked polyurethane polymers comprising diisocyanates and aliphatic hydrocarbon soft segments with a short-chain diol chain extender and a multifunctional amine and/or alcohol crosslinker to provide a polyurethane polymer with useful properties for the production of medical implant devices such as heart valves, are described. The polymers have an unexpected linear elastic region in a range from 5-100% and preferably between 10-35%.
Strait Access Technologies Holdings (pty) Ltd

Vagus nerve stimulation and subcutaneous defibrillation system

Systems and methods are provided for delivering vagus nerve stimulation and cardioversion/defibrillation therapies to patients for treating chronic heart failure. The vagus nerve stimulation and cardioversion/defibrillation therapies may be provided using a single implantable pulse generator, which can coordinate delivery of the therapies to provide an acute vagus nerve stimulation therapy in advance of delivering cardioversion-defibrillation energy..
Cyberonics, Inc.

Devices, heart valve replacement

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include a valve support having an upstream end and a downstream end extending around a longitudinal axis and having a cross-sectional shape.
Twelve, Inc.

Mechanical heart valve prosthesis for the right ventricle

A prosthetic heart valve having a pair of cooperating leaflets mounted in a valve body to alternate between an open position where the flow of blood in a downstream direction is permitted and a closed position where the flow of blood in the reverse direction is counteracted. Pivot member sets at diametrically opposite sides of each leaflet guide the leaflets moving between the open and closed positions, each set including an ear or a recess cooperating with an associated cavity or knob of an interior surface of the valve body.
Academisch Ziekenhuis Groningen

Holder for heart valve prostheses, corresponding storage arrangement, delivery instrument and kit

A holder for a heart valve prosthesis, the holder including a hub portion having a longitudinal axis, an engagement portion coupled to the hub portion and including plural finger members variably positionable relative to the hub portion between a collapsed condition wherein the finger members are closed onto the hub portion and an expanded condition wherein the finger members radially protrude with respect to the hub portion to engage a heart valve prosthesis.. .
Sorin Group Italia S.r.l.

Heartbeat-signal detecting device

A heartbeat-signal detecting device, which is for detecting a heartbeat signal of a living body, includes: (a) a gas-flow sensor configured to detect a flow rate of exhalation and inhalation passing through a trachea of the living body; (b) a gas-flow calculation controlling portion configured to output a respiration signal that reflects a respiratory motion of the living body, based on a signal outputted from the gas-flow sensor; (c) a waveform analysis controlling portion configured to extract, from the respiration signal, frequency components which are in synchronization with a pulse of a heart of the living body superimposed on the respiration signal, and to output a heartbeat signal representing a heartbeat waveform of the living body; and (d) a heartbeat-signal evaluation controlling portion is configured to evaluate a functional abnormality or an anatomic abnormality of the heart, based on the heartbeat signal analyzed by the waveform analysis controlling portion.. .
National University Corporation Nagoya University

Feature point identification mechanocardiography

A method to identify feature points associated with the heart valve movement, heart contraction or cardiac hemodynamics is revealed. The mechanocardiography (mcg) is a technology that makes use of vibrational waveforms acquired using at least one gravity sensor attached on one of the four heart valve auscultation sites on the body surface.
Chang Gung University

Methods and systems for obtaining physiologic information

The present invention discloses methods suitable for obtaining information related to at least one physiologic parameter of a person belonging to the group comprising respiration rate, heart rate, respiration rate variability, heart rate variability, temporal characteristics of at least a part of a heartbeat, and temporal characteristics of at least a part of a respiration cycle in a non-contact fashion. The present invention also discloses systems suitable for obtaining information related to at least one physiologic parameter of a person belonging to said group of physiologic parameters in a non-contact fashion..

Electronic monitoring, security, and communication device assembly

A method, system, and apparatus for security and monitoring are disclosed. In one embodiment, a small device with five sensors (temperature, light, motion, accelerometer, sound) includes a processor, local data storage, and wifi and bluetooth communication capabilities.
Rph Engineering, Llc

Heart valve sewing cuff

An embodiment of the invention includes a sewing cuff for aortic heart valves that better approximates native anatomy by better mating with the crown-like anatomical annulus. Limiting distortion of the crown-like annulus provides better blood flow and overall valve function and provides a physician greater ease of implantation since native anatomy is not flattened.
On-x Life Technologies, Inc.

Left heart assist device and method

A device, a kit and a method is presented for permanently augmenting the pump function of the left heart. The mitral valve plane is assisted in a movement along the left ventricular long axis during each heart cycle.
Synergio Ag

Coherent single layer high strength synthetic polymer composites for prosthetic valves

Thin, biocompatible, high-strength, composite materials are disclosed that are suitable for use in a prosthetic valve for regulating blood flow direction. In one aspect, the leaflet material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as a prosthetic heart valve leaflet.
W. L. Gore & Associates, Inc.

Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent

The invention relates to a prosthetic heart valve (100) for an endoprosthesis (1) used in the treatment of a stenotic cardiac valve and/or a cardiac valve insufficiency. The prosthetic heart valve (100) comprises of a plurality of leaflets (102), which consist of a natural and/or synthetic material and have a first opened position for opening the heart chamber and a second closed position for closing the heart chamber, the leaflets (102) being able to switch between their first and second position in response to the blood flow through the heart.
Jenavalve Technology, Inc.

Docking station for heart valve prosthesis

An anchoring device that can be positioned within a native valve, such as the native mitral valve, to secure a replacement prosthetic valve in place. The anchoring device can comprise a docking station formed of a super elastic wire-like member defining a continuous, closed shape.
Edwards Lifesciences Corporation

Device and treating vascular insufficiency

Embodiments of a leaflet clip device and method of reducing regurgitation through a native heart valve are disclosed. A leaflet clip device can include an elongated clipping member having a first end portion and a second end portion and a tensioning mechanism coupled to the clipping member.
Edwards Lifesciences Corporation

Stationary intra-annular halo designs for paravalvular leak (pvl) reduction - active channel filling cuff designs

A prosthetic heart valve may include a collapsible and expandable stent extending in a flow direction between a proximal end and a distal end, a cuff attached to an annulus section of the stent and having an outer surface facing in a radial direction orthogonal to the flow direction, a plurality of prosthetic valve leaflets attached to the cuff, and a sealing structure attached to the annulus section of the stent at an inner edge of the sealing structure. The flow direction may be defined from the proximal end toward the distal end.
St. Jude Medical, Cardiology Division, Inc.

Apparatus and intra-cardiac mapping and ablation

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a maze procedure.
Kardium Inc.

Magnetic navigation systems and methods

Systems and methods for forming a lesion on an endocardial tissue of a patients heart involve placing an ablation assembly inside of the heart and adjacent to the endocardial tissue, and placing a guiding assembly outside of the heart. An ablation assembly includes an ablation element and a first attraction element, and a guiding assembly includes a second attraction element.

Methods and devices for valve clip excision

A system for excising an implanted clip approximating opposed valve leaflets in a heart valve includes a capture catheter configured to be introduced proximate the valve leaflets on one side of the clip, a transfer catheter configured to be introduced proximate the valve leaflets on another side of the clip, and a cutting tool configured to be deployed between the capture and transfer catheters and to be engaged against tissue of at least one of the valve leaflets and to excise the clip. A removal catheter may optionally be used to remove the clip from the heart..
Revive Medical, Llc

Systems and methods to determine surrogates of blood pressure

Embodiments of the present disclosure relate to systems and methods for determining a subject's blood pressure using one or more implantable medical devices (imds). In an embodiment, a medical system comprises: at least one implantable medical device configured to sense signals associated with heart sounds of a subject and a processing unit communicatively coupled to the at least one implantable medical device.
Cardiac Pacemakers, Inc.

Identifying heartbeat messages

Examples relate to identifying heartbeat messages. In one example, a computing device may: obtain a plurality of messages that includes incoming messages and outgoing messages, each incoming message being sent from a server device to a client device, and each outgoing message being sent from the client device to the server device; identify candidate message pairs, each candidate message pair including one incoming message and one outgoing message; and identify a heartbeat message pair from the candidate message pairs based on at least one of: plurality of timestamps that includes i) incoming message timestamps that each correspond to one of the incoming messages, and ii) outgoing message timestamps that each correspond to one of the outgoing messages; a number of occurrences of each candidate message pair included a message log; or characteristics of data included in the incoming message and outgoing message of each candidate message pair..
Entit Software Llc

Remotely configurable routers with failover features, and methods and reliable web-based administration of same

Web-enabled routers are remotely and securely administered in a centralized fashion. A router receives a configuration profile from a dedicated web domain that maintains a repository of configuration profiles for multiple routers.
Datto, Inc.

Systems and methods for detecting wireless communication jamming in a network

An electronic device may include a processor and a network interface that may include a first radio and a second radio. The processor may be configured to perform wireless communication jamming attack detection by occasionally performing clear channel verification utilizing the network interface to determine whether a threshold number of devices' channels are incapacitated in a wireless network within a threshold amount of time and/or by sending a heartbeat signal from the first radio and determining whether the second radio received the heartbeat signal..
Google Inc.

Method of treating or ameliorating type 1 diabetes using fgf21

Methods of treating metabolic diseases and disorders using a fgf21 polypeptide are provided. In various embodiments the metabolic disease or disorder is type 1 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels, diabetic nephropathy, neuropathy, retinopathy, ischemic heart disease, peripheral vascular disease and cerebrovascular disease.
Amgen Inc.

Method of treating ischemic heart disease

A method of treating ischemic heart disease can include administering a therapeutically effective amount of a composition including date seed nanoparticles to a subject in need thereof. Exemplary suitable dosage forms can include tablet, gel, paste, and suspension.
King Abdulaziz University

Prosthetic heart valve devices and methods of valve repair

A mechanism for adjusting the chordae connecting the leaflets of a mitral valve to the papillary muscles in order to restore normal functioning of the mitral valve. The devices or mechanisms can correct problems associated with both prolapsed leaflets and restricted leaflets to allow the leaflets to properly coapt, thereby preventing or minimizing regurgitation.
Medtronic, Inc.

Systems and methods for heart valve therapy

Prosthetic mitral valves described herein can be deployed using a transcatheter mitral valve delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native mitral valve. This document describes prosthetic heart valve designs that interface with native mitral valve structures to create a fluid seal, thereby minimizing mitral regurgitation and paravalvular leaks.
Caisson Interventional, Llc

Method for replacing a heart valve

A method for replacing a native heart valve in need thereof comprises delivering to the native heart valve an apparatus comprising a valve member, a connecting member, and an anchor member suitable for anchoring the apparatus. The valve member reversibly moves between an open position and a closed position to augment or replace the function of the native valve leaflets, thereby reducing valve regurgitation.
Edwards Lifesciences Ag

Methods for anchoring a heart valve prosthesis in a transcatheter valve implantation procedure

Methods of deploying and securing a heart valve prosthesis are disclosed. A heart valve prosthesis (100) having a plurality of anchor guides (212) is loaded within a catheter-based delivery device, wherein each of the anchor guides is releasably engaged by a respective elongate member (338) and wherein tensioning of the elongate members aids in collapsing the prosthesis during loading.
Medtronic Vascular, Inc.

Inflatable transcatheter intracardiac devices and methods for treating incompetent atrioventricular valves

Inflatable heart valve implants and methods utilizing those valves designed to reduce or eliminate the regurgitant jet associated with an incompetent atrioventricular valve. The heart valve implants, which are deployed via a transcatheter venous approach, comprise an inflatable balloon portion movably connected to an anchored guide shaft and movable from a distal position in the ventricle to a more proximal position between leaflets of a native atrioventricular valve.

System and replacing an inflamed or infected heart valve

The invention relates to a system for replacing a heart valve that is diseased owing to inflammation and/or an infection. The system has: a stent system with at least one expandable stent; and a replacement heart valve which is secured to the at least one stent and has at least two heart valve leaflets.

Device and transcatheter heart valve repair under triangular resection technique

Medical device for transcatheter heart valve repair comprising a grasping tweezer (1) and a plicating tweezer (2), said grasping tweezer (1) being adapted to grasp a leaflet rim (3) and said plicating tweezer (2) comprising two rotatable flaps (4,5) and a central shaft (6) around which said flaps (4,5) may rotate in a “butterfly manner”, in such a way that the plicating tweezer (2) may adopt a closed or an open configuration. The invention also relates to a method for using this medical device..
Epygon

Toilet with a health monitoring torso belt

A toilet torso belt with sensors is disclosed. The torso belt is used by a toilet user while the toilet user is using the toilet to take health measurement readings of the user.

Baby sleep monitor

A sleep monitor for monitoring baby sleep uses sleep state classification based on heartbeat feature respiration features. The sleep monitor automatically retrains the classification during use of the sleep monitor.
Koninklijke Philips N.v.

Non-invasive measuring myocardial ischemia, stenosis identification, localization and fractional flow reserve estimation

The present disclosure facilitates the evaluation of wide-band phase gradient information of the heart tissue to assess, e.g., the presence of heart ischemic heart disease. Notably, the present disclosure provides an improved and efficient method to identify and risk stratify coronary stenosis of the heart using a high resolution and wide-band cardiac gradient obtained from the patient.
Analytics For Life

Dynamic heartbeating mechanism

System and method for providing failover protection for a cluster of host computers operates in one of two modes. When the number of host computers in the cluster is equal to or less than a threshold number, the host computers in the cluster operate in an all-active heartbeating mode in which each of the host computers is enabled to function as a master node.
Vmware, Inc.

Video display device system, heartbeat specifying method, heartbeat specifying program

A video display system capable of detecting heartbeat of a user by being mounted on the head of a user when used is provided. The video display system comprises a video display device that is mounted on the head of a user when used and a heartbeat detection device that detects the heartbeat of the user is provided, wherein video display device includes an acceleration sensor that sequentially outputs measured acceleration information and a first transmission unit that sequentially transmits the acceleration information to the heartbeat detection device, and the heartbeat detection device includes a first reception unit that receives the acceleration information transmitted from the video display device and a heartbeat detection unit that detects the heartbeat of the user from a waveform indicating a change in acceleration based on the received acceleration information..
Fove, Inc.

Prognosis of adverse events in patients with suspected chronic heart failure

The present invention is in the field of clinical diagnostics. Particularly the present invention relates to the prognosis of adverse events in patients with stable chronic heart failure or being suspected of having stable chronic heart failure by determination of the level of procalcitonin (pct)..
B.r.a.h.m.s. Gmbh

1,3-dihydroimidazole-2-thione derivatives as inhibitors of dopamine-beta-hydroxylase

Compounds of formula i and a method for their preparation are described, where r1, r2 and r3 are the same or different and signify hydrogens, halogens, alkyl, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino group; r4 signifies -alkyl-aryl or alkyl heteroaryl; x signifies ch2, oxygen atom or sulphur atom; n is 2 or 3; including the individual (r)- and (s)-enantiomers or mixtures of enantiomers thereof; and including pharmaceutically acceptable salts and esters thereof. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure..
Bial - Portela & Ca, S.a.

Implantable leadless pacemaker with atrial-ventricular synchronized pacing

An implantable leadless pacemaker (ilp) for a human or animal heart, wherein the ilp includes a housing, at least two electrode poles for picking up electrical potentials and/or delivering electrical stimulation, a stimulation control unit in connection with the electrode poles, a sensing unit that is in connection with at least one electrode pole, a signal processing unit in connection with the sensing unit, a signal evaluation unit in connection with the signal processing unit and/or the sensing unit, and an energy source. The sensing unit is configured to sense a first signal associated with an activity of the first heart chamber, and the stimulation control unit is configured to deliver electrical stimulation in the first heart chamber via the at least two electrode poles.
Biotronik Se & Co. Kg

Implantable leadless pacemaker with atrial-ventricular synchronized pacing

An implantable leadless pacemaker (ilp) for a human or animal heart is provided that includes a housing, at least two electrode poles for picking up electrical potentials and/or delivering electrical stimulation, a stimulation control unit in connection with the electrode poles, a sensing unit that is in connection with at least one electrode pole, a signal processing unit in connection with the sensing unit, a signal evaluation unit in connection with the signal processing unit and/or the sensing unit, and an energy source. The sensing unit is configured to sense a first signal associated with an activity of the first heart chamber, and the stimulation control unit is configured to deliver electrical stimulation in the first heart chamber via the at least two electrode poles.
Biotronik Se & Co. Kg

Method for reversing, preventing, delaying or stabilizing soft tissue calcification

The present invention provides methods of treating soft tissue calcification in a subject, comprising a step of administering to said subject an effective amount of ferric organic compound, such as ferric citrate. The claimed methods may prevent, reverse, delay or stabilize soft tissue calcification in a subject having chronic kidney disease.
Panion & Bf Biotech, Inc.

Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (ppar) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension.
Ardelyx, Inc

Compact crimping device

A compact crimping mechanism well-suited for use with devices such as stented prosthetic heart valves. The crimping mechanism includes a plurality of jaws configured for coordinated inward movement toward a crimping axis to reduce the size of a crimping iris around a stented valve.
Edwards Lifesciences Corporation

Prosthetic heart valve with compressible frames

A tubular portion of a valve frame circumscribes a longitudinal axis, and defines a lumen along the axis and a plurality of valve-frame coupling elements disposed circumferentially around the axis. An outer frame: (a) comprises a ring defined by a pattern of alternating peaks and troughs, the pattern having an amplitude, (b) comprises a plurality of legs, coupled to the ring at respective troughs, and (c) is shaped to define a plurality of outer-frame coupling elements, each coupled to the ring, and fixed with respect to a respective valve-frame coupling element.
Mitraltech Ltd.

Heart valve prosthesis

A device for artificial cardiac valve support, the device including an upstream portion designed to expand to have at least one dimension wider than a native heart valve annulus, a downstream portion attached to the upstream portion, the downstream portion also designed to expand to have at least a portion with at least one dimension wider than a native heart valve annulus, and a plurality of artificial valve commissure posts. A method for producing a device for artificial cardiac valve support, the method including producing an upstream portion, producing a downstream portion, and attaching the upstream portion to the downstream portion, producing a frame for artificial cardiac valve support.
Mitrassist Medical Ltd.

Modified consensus protocol for eliminating heartbeat network traffic

A computing system in data communication with a plurality of nodes that make up a distributed computing cluster can detect an absence of communication from a node of the plurality of nodes over a time period that exceeds a predefined threshold time period. The computing system can query an instance of a central topology manager for the plurality of nodes regarding liveness of the node from which the absence of communication was detected and can attempting to re-initiate communication with the node when the instance of the central topology manager indicates that the node is live..
Sap Se

Method and system for creating and managing aggregation service hierarchies

Techniques disclosed herein provide an approach for creating and managing aggregation service hierarchies, such as hierarchies used in distributed scheduling services and heartbeat services. In one embodiment, management nodes accept host computer registration events and add host computers to a hierarchy used as the aggregation mechanism in an aggregation service.
Vmware, Inc.

Semi-automated heart valve morphometry and computational stress analysis from 3d images

A method is provided for measuring or estimating stress distributions on heart valve leaflets by obtaining three-dimensional images of the heart valve leaflets, segmenting the heart valve leaflets in the three-dimensional images by capturing locally varying thicknesses of the heart valve leaflets in three-dimensional image data to generate an image-derived patient-specific model of the heart valve leaflets, and applying the image-derived patient-specific model of the heart valve leaflets to a finite element analysis (fea) algorithm to estimate stresses on the heart valve leaflets. The images of the heart valve leaflets may be obtained using real-time 3d transesophageal echocardiography (rt-3dtee).
The Trustees Of The University Of Pennsylvania

Pooled memory heartbeat in shared memory architecture

Examples provide a pooled memory heartbeat for virtual machine hosts. A virtual controller creates a pooled memory heartbeat file system in a shared memory partition of a pooled memory.
Vmware, Inc.

Method of site isolation protection, electronic device and system using the same method

A method of site isolation protection includes the following steps. A set of clustered engines including a first engine at a first site and a second engine at a second site is provided.
Weixu Technology Co. Ltd.

Centrifugal pumps for medical uses

Extracorporeal circuit devices can be used for on-pump open-heart surgery to support surgical procedures such as coronary artery bypass grafting. In some cases, a centrifugal pump is used as part of an extracorporeal circuit.
Terumo Cardiovascular Systems, Inc.

Methods and renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease.
Medtronic Ardian Luxembourg S.a.r.l.

Integral artificial heart device

Integral artificial heart device capable of storing venous blood in dynamic atria, without interrupting the continuous return of the blood. The device comprises a right ventricle (a1) and left ventricle (a2) pulsing simultaneously, and the reactive right atrium (c1) and left atrium (not illustrated) thereof, immersed in a pneumatic spec (d) having a variable vacuum d, which is driven by a solenoid (35), acting sequentially, by repulsion, on the permanent magnet discs (20, 21) included in the elastic ventricular membranes (18, 19), which beat simultaneously in the ventricular spaces (a1) and (a2), and, in the opposite direction, in pneumatic space (d) which houses elastic tubes acting as atria.

Centrifugal pumps for medical uses

Extracorporeal circuit devices can be used for on-pump open-heart surgery to support surgical procedures such as coronary artery bypass grafting. In some cases, a centrifugal pump is used as part of an extracorporeal circuit.
Terumo Cardiovascular Systems, Inc.

Modulators of the prostacyclin (pgi2) receptor useful for the treatment of disorders related thereto

The present invention relates to amide derivatives of formula (xiiia) and pharmaceutical compositions thereof that modulate the activity of the pgi2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of: pulmonary arterial hypertension (pah); idiopathic pah; familial pah; pah associated with a collagen vascular disease, a congenital heart disease, portal hypertension, hiv infection, ingestion of a drug or toxin, hereditary hemorrhagic telangiectasia, splenectomy, pulmonary veno-occlusive disease (pvod) or pulmonary capillary hemangiomatosis (pch); pah with significant venous or capillary involvement; platelet aggregation; coronary artery disease; myocardial infarction; transient ischemic attack, angina; stroke; ischemia-reperfusion injury; restenosis; atrial fibrillation; blood clot formation in an angioplasty or coronary bypass surgery individual or in an individual suffering from atrial fibrillation; atherosclerosis; atherothrombosis; asthma or a symptom thereof; a diabetic-related disorder such as diabetic peripheral neuropathy, diabetic nephropathy or diabetic retinopathy; glaucoma or other disease of the eye with abnormal intraocular pressure; hypertension; inflammation; psoriasis; psoriatic arthritis; rheumatoid arthritis; crohn's disease; transplant rejection; multiple sclerosis; systemic lupus erythematosus (sle); ulcerative colitis; ischemia-reperfusion injury; restenosis; atherosclerosis; acne; type 1 diabetes; type 2 diabetes; sepsis; and chronic obstructive pulmonary disorder (copd)..
Arena Pharmaceuticals, Inc.

Systems and methods for manufacturing a stent frame

A prosthetic heart valve can include a support structure, an actuator member, and a plurality of leaflets. The support structure can have a plurality of struts and a plurality of rivets.
Edwards Lifesciences Cardiaq Llc

Integrated heart valve delivery system

An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent.
Edwards Lifesciences Corporation

Heart valve prosthesis with outer skirt

A heart valve prosthesis includes a heart valve encircled by a base body in a peripheral direction to hold the heart valve. The heart valve is fastened to the base body and arranged in its interior.
Biotronik Ag

Delivery system for percutaneous delivery and implantation of atrioventricular heart valves

Described is a delivery system for percutaneous delivery and implantation of a heart valve. The delivery system includes a handle with a sheath extending therefrom.
The Regents Of The University Of California

System and positioning an artificial heart valve at the position of a malfunctioning valve of a heart through a percutaneous route

Method for positioning an artificial heart valve at the anatomic position of a malfunctioning heart valve of a heart of a patient, by employing a catheter bearing the artificial heart valve and a valve fixation device, at the tip of the catheter, the method including the procedures of receiving a marking input associated with an image of the heart, and respective of the anatomic position, in a medical positioning system (mps) coordinate system, moving the tip toward the anatomic position, constantly detecting the current position of the artificial heart valve, and producing an indication when the current position substantially matches the anatomic position, thereby enabling the catheter to fix the malfunctioning heart valve in place, by the valve fixation device.. .
Mediguide Ltd.

Method for the detecting electrocardiogram anomalies and corresponding system

A heart-rate associated with a heartbeat signal is determined. A transform is selected based on the determined heart-rate associated with the heartbeat signal and a reference heart-rate associated with a dictionary of a sparse approximation model.
Politecnico Di Milano

Congenital heart disease monitor

A congenital heart disease monitor utilizes a sensor capable of emitting multiple wavelengths of optical radiation into a tissue site and detecting the optical radiation after attenuation by pulsatile blood flowing within the tissue site. A patient monitor is capable of receiving a sensor signal corresponding to the detected optical radiation and calculating at least one physiological parameter in response.
Masimo Corporation

Application agnostic sensor, control computer and methods for operating

A server computer includes a non-transitory data storage storing a plurality of control rule sets including a first control rule set and a second control rule set, an interface transmitting, over a network, the first control rule set in response to a signal from the multi-application-transceiver device such that loading of application specific settings of the first control rule set causes a first health monitoring application to be enabled on the multi-application-transceiver device, and a health data analyzer receiving, over the network, a processed signal from the multi-application-transceiver device, where the processed signal includes information relating to monitoring a heartbeat or breathing of the person, detection of sudden infant death syndrome (sids) of the person, or detection of a concentration of macromolecules on the person. The health data analyzer performs an analysis on the processed signal, and communicates, over the network, results of the analysis to the multi-application-transceiver device..

Sealing structure for heart valve implants

A heart valve implant comprising a supporting stent, a heart valve element, and a skirt, the skirt includes or is formed of at least one molded body, wherein the molded body is made of dried treated bacterial cellulose that has a swelling capacity that is greater than untreated bacterial cellulose of the same type.. .
Biotronik Ag

System and cardiac valve repair and replacement

A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween..

Transcatheter valve delivery system with crimped prosthetic heart valve

Stented prosthetic heart valve crimping tools and methods, and transcatheter delivery systems for delivering a crimped prosthetic heart valve. Methods of the present disclosure include crimping or compressing a stented prosthetic heart valve via spherical compression to a spherically compressed shape, and then delivering the so-shaped prosthesis to a target site.
Medtronic Vascular, Inc.

Replacement heart valve

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve.
Edwards Lifesciences Cardiaq Llc

Replacement heart valve

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve.
Edwards Lifesciences Cardiaq Llc

Methods and systems for multi-site stimulation

Systems and methods for multi-site cardiac stimulation are disclosed. The system includes an electrostimulation circuit to deliver electrostimulation to one or more candidate sites of at least one heart chamber.
Cardiac Pacemakers, Inc.

Compositions and use of a-type procyanidins

The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing a-type procyanidins, and methods of use thereof, for prophylactic or therapeutic treatment of a human or a veterinary animal to treat or prevent no-responsive health conditions, treat hypertension, cardiovascular disease, coronary artery disease and/or vascular circulation disorders, prevent or reduce the risk of heart attack, stroke, congestive heart failure and/or kidney failure, or to improve blood flow, for example renal blood flow. The composition may optionally contain an additional no modulating agent and/or a cardiovascular-protective or therapeutic agent, or may be administered in combination with such an agent..
Mars, Incorporated

Heart valve leaflet capture device

The invention provides a heart valve leaflet capture device (250) comprising a cardiac catheter probe having a proximal end for manipulating the device (250) and a distal end terminating in a transvalve element (256). The transvalve element (256) is configured to pass through a heart valve generally parallel to a longitudinal axis of the catheter and includes two or three leaflet gripping elements (252).
Strait Access Technologies Holdings (pty) Ltd

Transcatheter prosthetic heart valve delivery system with protective feature

Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a covering feature associated with the spindle for selectively covering at least a portion of a stented prosthetic heart valve tethered to the spindle in a delivery state.
Medtronic Vascular, Inc.

Transcatheter prosthetic heart valve delivery system with lateral offset control

Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature.
Medtronic Vascular, Inc.

Method of replacing mitral valve

A method of implanting a prosthetic mitral heart valve includes advancing a guidewire through a femoral vein, an atrial septum, and a native mitral valve. A guide catheter is advanced over the guidewire and a delivery catheter is advanced through the guide catheter.
Edwards Lifesciences Coporation

Crimping device

A crimping system for a prosthetic heart valve comprises an elongate rigid body and a radially flexible, tubular sock. The body has an inner lumen extending along a central longitudinal axis between an insertion end and an outlet end.
Edwards Lifesciences Corporation

Transcatheter valve delivery system with septum hole closure tip assembly

Transcatheter heart valve delivery systems having a tip assembly configured to close the hole or perforation made in a patient's septal wall after transseptal delivery of a stented prosthetic heart valve to a defective heart valve (e.g., a mitral valve). The delivery device is configured to permit in vivo release of the tip assembly immediately after deployment of the stented prosthetic heart valve to implant the tip assembly into the septal wall proximate the hole through which the stented prosthetic heart valve is delivered.
Medtronic Vascular, Inc.

Foot pulse oximeter for screening congenital heart disease before newborn discharge

A method including placing a portion of a foot of a newborn in a device, the device including a light emitter and a corresponding receiver coupled on opposite sides of the device, the device further including a processor for processing data from the light emitter and receiver; and determining a presence of congenital heart disease. An apparatus including a body including a chamber of a size to accommodate a portion of a newborn's foot; at least one light emitter and a corresponding detector coupled on opposite sides of the body, the emitter configured to emit light of a prescribed wavelength into the chamber; and a processor coupled to the body and configured to receive a signal from the at least one detector..
Los Angeles Biomedical Research Institute At Harbor-ucla Medical Center

Link management method, device and system in virtual machine environment

At least some embodiments of invention provide a method, device and system for link management in a virtual machine (vm) environment. The method includes: a heartbeat handshake link is established with a vm.
Zte Corporation

Methods for treating hypercholesterolemia

Disclosed herein are antisense compounds and methods for decreasing ldl-c in an individual having elevated ldl-c. Additionally disclosed are antisense compounds and methods for treating, preventing, or ameliorating hypercholesterolemia and/or atherosclerosis.
Ionis Pharmaceuticals, Inc.

Blood treatment machine having electrical heartbeat analysis

A blood treatment machine includes a blood pump; an arterial line in fluid communication with the blood pump; a venous line; and a heartbeat evaluation system including (i) a first electrode coupled to the arterial line or to a patient, (ii) a second electrode coupled to the venous line, (iii) electronic circuitry communicating electrically with the first electrode and the second electrode to sense an electrical heartbeat signal generated by the patient, and (iv) signal processing configured to use the sensed heartbeat signal to calculate at least one of (a) heart rate, (b) respiration, (c) stroke volume, (d) cardiac output, or (e) central blood volume.. .
Baxter Healthcare Sa

Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (ppar) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension.
Ardelyx, Inc.

Implantable prosthetic valve with non-laminar flow

A prosthetic heart valve can include an expandable support stent, a valve assembly, and a connecting membrane. The support stent can have first and second end portions and can be configured to be radially expandable from a first configuration to a second configuration.
Edwards Lifesciences Corporation

Replacement valve and anchor

Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve.
Boston Scientific Scimed, Inc.

Automated condition screening and detection

Embodiments are disclosed that enable an electronic device to instruct as user how to user one or more noninvasive sensors to measure one or more physiological parameters of a patient. In one embodiment, the measured parameters are used to obtain a diagnosis, such as a diagnosis of a critical congenital heart defect..
Masimo Corporation

Method for the detecting electrocardiogram anomalies and corresponding system

A heartrate monitor detects heartbeats in a test signal. A local heartrate and an energy of acceleration are associated with the detected heartbeats.
Politecnico Di Milano

Auxiliary component for an equipment for cardiac autonomic neuropathy test and equipment that includes such a component

Equipment for carrying out cardiac autonomic neuropathy tests includes a base unit to which a mouthpiece is connected, forming an autonomous system for measuring the pressure and/or the pattern of breath, provided with a series of leds aimed at informing a patient, who is undergoing the test, about correctness or incorrectness of a test execution. The mouthpiece is provided with a flow sensor, aimed at measuring a patient's pattern of breath, and a pressure sensor.
Meteda S.r.l.





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