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Heart patents

      

This page is updated frequently with new Heart-related patent applications.

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 Methods and systems for multi-site stimulation patent thumbnailMethods and systems for multi-site stimulation
Systems and methods for multi-site cardiac stimulation are disclosed. The system includes an electrostimulation circuit to deliver electrostimulation to one or more candidate sites of at least one heart chamber.
Cardiac Pacemakers, Inc.


 Compositions and  use of a-type procyanidins patent thumbnailCompositions and use of a-type procyanidins
The invention relates to compositions, such as pharmaceuticals, foods, food additives, or dietary supplements, containing a-type procyanidins, and methods of use thereof, for prophylactic or therapeutic treatment of a human or a veterinary animal to treat or prevent no-responsive health conditions, treat hypertension, cardiovascular disease, coronary artery disease and/or vascular circulation disorders, prevent or reduce the risk of heart attack, stroke, congestive heart failure and/or kidney failure, or to improve blood flow, for example renal blood flow. The composition may optionally contain an additional no modulating agent and/or a cardiovascular-protective or therapeutic agent, or may be administered in combination with such an agent..
Mars, Incorporated


 Heart valve leaflet capture device patent thumbnailHeart valve leaflet capture device
The invention provides a heart valve leaflet capture device (250) comprising a cardiac catheter probe having a proximal end for manipulating the device (250) and a distal end terminating in a transvalve element (256). The transvalve element (256) is configured to pass through a heart valve generally parallel to a longitudinal axis of the catheter and includes two or three leaflet gripping elements (252).
Strait Access Technologies Holdings (pty) Ltd


 Transcatheter prosthetic heart valve delivery system with protective feature patent thumbnailTranscatheter prosthetic heart valve delivery system with protective feature
Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a covering feature associated with the spindle for selectively covering at least a portion of a stented prosthetic heart valve tethered to the spindle in a delivery state.
Medtronic Vascular, Inc.


 Transcatheter prosthetic heart valve delivery system with lateral offset control patent thumbnailTranscatheter prosthetic heart valve delivery system with lateral offset control
Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature.
Medtronic Vascular, Inc.


 Method of replacing mitral valve patent thumbnailMethod of replacing mitral valve
A method of implanting a prosthetic mitral heart valve includes advancing a guidewire through a femoral vein, an atrial septum, and a native mitral valve. A guide catheter is advanced over the guidewire and a delivery catheter is advanced through the guide catheter.
Edwards Lifesciences Coporation


 Crimping device patent thumbnailCrimping device
A crimping system for a prosthetic heart valve comprises an elongate rigid body and a radially flexible, tubular sock. The body has an inner lumen extending along a central longitudinal axis between an insertion end and an outlet end.
Edwards Lifesciences Corporation


 Transcatheter valve delivery system with septum hole closure tip assembly patent thumbnailTranscatheter valve delivery system with septum hole closure tip assembly
Transcatheter heart valve delivery systems having a tip assembly configured to close the hole or perforation made in a patient's septal wall after transseptal delivery of a stented prosthetic heart valve to a defective heart valve (e.g., a mitral valve). The delivery device is configured to permit in vivo release of the tip assembly immediately after deployment of the stented prosthetic heart valve to implant the tip assembly into the septal wall proximate the hole through which the stented prosthetic heart valve is delivered.
Medtronic Vascular, Inc.


 Foot pulse oximeter for screening congenital heart disease before newborn discharge patent thumbnailFoot pulse oximeter for screening congenital heart disease before newborn discharge
A method including placing a portion of a foot of a newborn in a device, the device including a light emitter and a corresponding receiver coupled on opposite sides of the device, the device further including a processor for processing data from the light emitter and receiver; and determining a presence of congenital heart disease. An apparatus including a body including a chamber of a size to accommodate a portion of a newborn's foot; at least one light emitter and a corresponding detector coupled on opposite sides of the body, the emitter configured to emit light of a prescribed wavelength into the chamber; and a processor coupled to the body and configured to receive a signal from the at least one detector..
Los Angeles Biomedical Research Institute At Harbor-ucla Medical Center


 Link management method, device and system in virtual machine environment patent thumbnailLink management method, device and system in virtual machine environment
At least some embodiments of invention provide a method, device and system for link management in a virtual machine (vm) environment. The method includes: a heartbeat handshake link is established with a vm.
Zte Corporation


Methods for treating hypercholesterolemia

Disclosed herein are antisense compounds and methods for decreasing ldl-c in an individual having elevated ldl-c. Additionally disclosed are antisense compounds and methods for treating, preventing, or ameliorating hypercholesterolemia and/or atherosclerosis.
Ionis Pharmaceuticals, Inc.

Blood treatment machine having electrical heartbeat analysis

A blood treatment machine includes a blood pump; an arterial line in fluid communication with the blood pump; a venous line; and a heartbeat evaluation system including (i) a first electrode coupled to the arterial line or to a patient, (ii) a second electrode coupled to the venous line, (iii) electronic circuitry communicating electrically with the first electrode and the second electrode to sense an electrical heartbeat signal generated by the patient, and (iv) signal processing configured to use the sensed heartbeat signal to calculate at least one of (a) heart rate, (b) respiration, (c) stroke volume, (d) cardiac output, or (e) central blood volume.. .
Baxter Healthcare Sa

Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (ppar) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment of hypertension.
Ardelyx, Inc.

Implantable prosthetic valve with non-laminar flow

A prosthetic heart valve can include an expandable support stent, a valve assembly, and a connecting membrane. The support stent can have first and second end portions and can be configured to be radially expandable from a first configuration to a second configuration.
Edwards Lifesciences Corporation

Replacement valve and anchor

Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve.
Boston Scientific Scimed, Inc.

Automated condition screening and detection

Embodiments are disclosed that enable an electronic device to instruct as user how to user one or more noninvasive sensors to measure one or more physiological parameters of a patient. In one embodiment, the measured parameters are used to obtain a diagnosis, such as a diagnosis of a critical congenital heart defect..
Masimo Corporation

Method for the detecting electrocardiogram anomalies and corresponding system

A heartrate monitor detects heartbeats in a test signal. A local heartrate and an energy of acceleration are associated with the detected heartbeats.
Politecnico Di Milano

Auxiliary component for an equipment for cardiac autonomic neuropathy test and equipment that includes such a component

Equipment for carrying out cardiac autonomic neuropathy tests includes a base unit to which a mouthpiece is connected, forming an autonomous system for measuring the pressure and/or the pattern of breath, provided with a series of leds aimed at informing a patient, who is undergoing the test, about correctness or incorrectness of a test execution. The mouthpiece is provided with a flow sensor, aimed at measuring a patient's pattern of breath, and a pressure sensor.
Meteda S.r.l.

Flow-based adaptive private network with multiple wan-paths

Systems and techniques are described which improve performance, reliability, and predictability of networks without having costly hardware upgrades or replacement of existing network equipment. An adaptive communication controller provides wan performance and utilization measurements to another network node over multiple parallel communication paths across disparate asymmetric networks which vary in behavior frequently over time.
Talari Networks Incorporated

Method and device for processing failure in at least one distributed cluster, and system

A method and a device for processing a failure in at least one distributed cluster, and a system, where the at least one distributed cluster includes a first distributed cluster. The first distributed cluster includes a first master node, a first slave node, a first reference node, and a first secondary node that serves as a backup of the first master node.
Huawei Technologies Co., Ltd.

Machine learning system for assessing heart valves and surrounding cardiovascular tracts

A machine learning system for evaluating at least one characteristic of a heart valve, an inflow tract, an outflow tract or a combination thereof may include a training mode and a production mode. The training mode may be configured to train a computer and construct a transformation function to predict an unknown anatomical characteristic and/or an unknown physiological characteristic of a heart valve, inflow tract and/or outflow tract, using a known anatomical characteristic and/or a known physiological characteristic the heart valve, inflow tract and/or outflow tract.
Stenomics, Inc.

System and non-invasively controlling autonomic nerve activity using skin

System and methods for monitoring and/or controlling nerve activity in a subject are provided. In one embodiment, a system includes electrodes configured to be placed proximate to a subject's skin, and a signal detector configured to detect electrical signals using the electrodes.
Indiana University Research & Technology Corporation

Corkscrew shape for right-sided cardiac device

A catheter includes a catheter body, a pump assembly and a cannula. The pump assembly can be disposed at a distal end of the catheter body and has a distal portion.
Abiomed, Inc.

Transcatheter prosthetic heart valve and delivery system

A prosthetic heart valve for an endoprosthesis used in the treatment of a stenotic heart valve and/or a heart valve insufficiency. The prosthetic heart valve comprises a plurality of leaflets (3,4,5) which are able to switch between their open and close position in response to the blood flow through the heart.

Replacement heart valve implant with inflow stitching

A replacement heart valve implant may include a tubular anchor member actuatable between a delivery and a deployed configuration, the tubular anchor member including an inflow end, an outflow end, and a plurality of anchor member intersection points, and defining a longitudinal axis extending from the inflow end to the outflow end, a plurality of valve leaflets, and a seal member secured to the tubular anchor member at the inflow end. An end surface of each of the plurality of valve leaflets may abut an inner-facing surface of the seal member.
Boston Scientific Scimed, Inc.

Prosthetic heart valve with cusp positioners

A prosthetic heart valve has three cusp regions positioned at an inflow end intermediate three commissure regions positioned at an outflow end thereof. A support frame including three cusp positioners is fixed with respect to a leaflet frame and located intermediate each pair of adjacent commissure regions.
Edwards Lifesciences Corporation

Patient specific scan parameters for mri scanning

A method of optimizing scan parameters for lge-mri. At least one cardiac mri ti scout scan is performed by applying an inversion pulse every predetermined heartbeat of a patient.
University Of Utah Research Foundation

High-impedance fault detection using coordinated devices

A conductor-mounted device (cmd) used to signal an intelligent electronic device (ied) of the existence of a fault on a portion of the electric power delivery system is described herein. The cmd may provide a heartbeat signal to the ied.
Schweitzer Engineering Laboratories, Inc.

Methods and renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease.
Medtronic Ardian Luxembourg S.a.r.l.

Compositions and methods for treating heart failure

The present invention provides methods for treating chronic heart failure patients using the medication comprising neureplin. The methods comprise first performing a companion diagnostic test of each patient before treatment; and then providing a suitable treatment to the patient according to the results of the companion diagnostic test.
Zensun (shanghai) Science & Technology, Co., Ltd.

Mitral valve delivery device

A delivery device for a collapsible prosthetic heart valve may include a catheter assembly and an operating handle. The catheter assembly may include an inner shaft around which a compartment is defined, and a distal sheath having proximal and distal segments configured to enclose the compartment.
St. Jude Medical, Cardiology Division, Inc.

Heart valve implant and methods for delivering and implanting same

heart valve implants and methods for implanting and delivering same are described. A heart valve implant can include a shaft, having a first end and a second end, an anchor, and a plurality of wafers.
Cardiosolutions, Inc.

Stented prosthetic heart valve with variable stiffness and methods of use

A prosthetic heart valve including a stent frame and a valve structure. The valve structure is disposed within a lumen of the stent frame.
Medtronic Vascular Galway

Mitral heart valve replacement

A prosthetic heart valve having an inflow end, an outflow end and a longitudinal axis extending from the inflow end to the outflow end includes a collapsible and expandable stent including a plurality of cells arranged in at least one row extending around a circumference of the stent. The stent further includes at least one engaging arm joined to one of the cells adjacent the outflow end and having a free end extending toward the inflow end, the engaging arm being movable between a loaded condition in which the engaging arm is oriented substantially parallel with the longitudinal axis of the stent, a partially-released condition in which the engaging arm forms a first angle with the longitudinal axis of the stent, and a fully-released condition in which the engaging arm forms a second angle with the longitudinal axis of the stent, the first angle being larger than the second angle..
St. Jude Medical, Cardiology Division, Inc.

Heart valve with stent having varying cell densities

A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent extending between a proximal end and a distal end, the stent including an annulus section adjacent the proximal end and an aortic section adjacent the distal end. The annulus section has cells arranged in at least one annulus row, each annulus row having a same first number of cells, the first number defining a first cell density.
St. Jude Medical, Cardiology Division, Inc.

Suturing rings for prosthetic heart valves

The present subject matter describes a suturing rings and method of manufacture of suturing rings for prosthetic heart valves. A plurality of suture holes are formed along a length of the metal sheet by performing punching or similar operations.

Replacement heart valve implant with invertible leaflets

A locking mechanism for a medical implant may include a buckle member, a post member axially translatable with respect to the buckle member, the post member including a receiving portion proximate a proximal end of the post member, a distal end, a laterally-arched central body portion extending between the receiving portion and the distal end, and a cantilevered leg extending proximally from the distal end, and an actuator element including a proximal shaft portion and a distal engagement portion, the distal engagement portion being configured to releasably engage the receiving portion of the post member. The proximal shaft portion may be pivotable with respect to the distal engagement portion..
Boston Scientific Scimed, Inc.

Remote monitoring device

A remote monitoring device is connected to a rubber strap and contains: a controller, a global system for mobile communication (gsm), a global positioning system (gps), a wi-fi & blue tooth, and a near field communication (nfc). The controller includes a microprocessor, a blood pressure sensing unit, a heartbeat sensing unit, a temperature sensing unit, and a wireless signal transmitting unit.

Method for extracting heart information based on micro movements of human body

A method of extracting heart information from a body micro-movement is provided. The method includes a face tracking step, a frame difference averaging step, smoothing filtering step, and a sliding peak detection step..
Sangmyung University Industry-academy Cooperation Foundation

Biomarkers and methods of prediction

Subject of the present invention are biomarkers and methods for the identification of risk for subsequent cardiovascular event (e.g. Coronary heart disease death, non-fatal myocardial infarction, ischemic stroke, hospitalizations for unstable angina pectotis, cardiac arrest) in patients that have experienced an acute coronary syndrome, comprising the detecting the level of nt-probnp, homocysteine and crp..
Hoffmann-la Roche Inc.

Neurostimulation in a neural fulcrum zone for the treatment of chronic cardiac dysfunction

Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone.
East Tennessee State University

Heart valve delivery catheter with safety button

Valve delivery catheter assemblies including components that limit trauma to the expanded prosthetic valve and body channels as the distal tip of the catheter is withdrawn through the expanded valve and thereafter from the body. Catheter assemblies according to the present invention can include a handle assembly, an introducer sheath, and a distal tip assembly.
Medtronic, Inc.

Systems of heart valve delivery on a beating heart

A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex.
Edwards Lifesciences Corporation

Elastomeric leaflet for prosthetic heart valves

A leaflet for a prosthetic valve formed of at least one layer that includes a composite material containing at least one expanded fluoropolymer membrane having serpentine fibrils and an elastomer is provided. The fluoropolymer may be polytetrafluoroethylene.
W. L. Gore & Associates, Inc.

Everting heart valve

The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve.
Boston Scientific Scimed, Inc.

Leaflet stitching backer

A replacement heart valve post and leaflet assembly may include at least a first post member including a body portion, a cantilevered leg portion, and a hinge portion configured to connect the body portion and the cantilevered leg portion and one or more leaflets. The cantilevered leg portion may comprise a longitudinally extending slot defined therein.
Boston Scientific Scimed, Inc.

Apparatus and methods for anterior valve leaflet management

In some embodiments, a method includes delivering to a native valve annulus (e.g., a native mitral valve annulus) of a heart a prosthetic heart valve having a body expandable from a collapsed, delivery configuration to an expanded, deployed configuration. The method can further include, after the delivering, causing the prosthetic heart valve to move from the delivery configuration to the deployed configuration.
Tendyne Holdings, Inc.

System for screening of the state of oxygenation of a subject

The present invention relates to a processor and a system (1, 1′) for screening of the state of oxygenation of a subject (100), in particular for screening of newborn babies for congenital heart disease. The system comprises an imaging unit (2) for obtaining a plurality of image frames of the subject (100) over time, and a processor (3) for processing the image frames.
Koninklijke Philips N.v.

Method and detection of heartbeat characteristics

Aspects of the present disclosure are directed to detecting atrial fibrillation (af). As may be implemented in accordance with one or more embodiments, a time series of inter-beat intervals is computed from a recording of activity of a beating heart.
Vivaquant Llc

System and providing an indication of the well-being of an individual

Systems and methods for providing an indication of the well-being of an individual are disclosed. In particular, the systems and methods utilizes data obtained from physical sensors such as heartbeat monitors and social media platforms for deriving and/or assigning an indication of the individual's feelings or emotional well-being, are described..

Heartbeat period setting method, and terminal

Embodiments of the present invention disclose a heartbeat period setting method, including: setting a heartbeat period of a tested application to t2 and performing a first heartbeat test; setting heartbeat periods of multiple applications to ti if the first heartbeat test is not passed, and performing heartbeat services; or setting the heartbeat period of the tested application to t3 if the first heartbeat test is passed, and performing a second heartbeat test; and setting the heartbeat periods of the multiple applications to t2 if the second heartbeat test is not passed, and performing heartbeat services; or setting the heartbeat period of the tested application to t4 if the second heartbeat test is passed, and performing a third heartbeat test, where t1<t2<t3<t4. The embodiments of the present invention further disclose a corresponding mobile terminal.

Service providing device, alternative service providing device, relaying device, service providing system, and service providing method

A service providing device included in a process control system in a plant, the service providing device includes a communicator configured to perform communication via a network, a service provider configured to provides a service via the communicator by exclusively assigning first identification information to one of the service providing device and an alternative service providing device, the first identification information being common to the alternative service providing device which provides the service instead of the service providing device, and a heartbeat transmitter configured to transmit heartbeat information for notifying that the service is normal to the alternative service providing device via a relaying device by using second identification information which is different from the first identification information.. .

Storage network element discovery method and apparatus

A storage network element discovery method and an apparatus, where the method includes broadcasting or multicasting, by a control network element, a heartbeat message to at least one storage network element, where the heartbeat message includes address information of the control network element, receiving, by the control network element, a response message returned by at least one storage network element according to the heartbeat message, and determining an accessible storage network element according to the response message, where the response message includes network parameter information of the corresponding storage network element. Therefore, in a storage array, by broadcasting or multicasting a heartbeat message and according to a reply from a storage network element, a control network element may determine a storage network element that can be accessed by the control network element..

Device and regulating pressure in a heart chamber

A device for regulating blood pressure in a heart chamber is provided. The device includes a shunt positionable within a septum of the heart.

Short acting phenylalkylamine calcium channel blockers and uses thereof

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods..

Short acting phenylalkylamine calcium channel blockers and uses thereof

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods..

Short acting phenylalkylamine calcium channel blockers and uses thereof

The present invention relates to the use of a pharmaceutically effective amount of an short-acting calcium channel blocking compound to treat ischemic heart conditions, cardiac arrhythmias, hypertensive crisis in an emergency room setting, hypertension before, during, or after surgery, no-reflow phenomenon following reperfusion, and diseases associated with decreased skeletal muscle blood flow. The invention also relates to pharmaceutical compositions formulated for use in such methods and to kits for such methods..

Prosthetic heart valve devices with tethered anchors and associated systems and methods

Prosthetic heart valve devices with tethered anchors and associated systems and methods are disclosed herein. A heart valve device configured in accordance with embodiments of the present technology can include, for example, a valve support for carrying a prosthetic valve.

Expandable epicardial pads and devices and methods for delivery of same

Apparatus and methods are described herein for use in the delivery of a prosthetic mitral valve. In some embodiments, an apparatus includes an epicardial pad configured to engage an outside surface of a heart to secure a prosthetic heart valve in position within the heart.

Truncated cone heart valve stent

A heart valve stent having a section with a heart valve implant and several proximally disposed tissue anchors, also comprising a plurality of anchoring threats, each with a proximate end fastened to the stent or valve and a distal end attached to tissue within a heart chamber to provide tension between the heart chamber tissue and the stent.. .

Stent assembly for use in prosthetic heart valves

A prosthetic heart valve having a cuff attached to a stent provides a seal for preventing paravalvular leakage. The cuff may be constructed from known sealing materials to fill in and around paravalvular leakage gaps, while continuously collapsing down into a low profile volume within the stent.

Heart valve prosthesis

A heart valve prosthesis includes a valve frame (2), on which frame several valve leaflets (8) are fastened, as well as a fastening region which connects axially onto the valve frame (2), for fastening in a blood vessel. The fastening region includes a stabilizing ring (14, 14′, 14″, 14″′, 14″″) which defines a given shape and a given diameter and is connected to the valve frame (2) is a force-decoupled manner..

High-frequency device

A high-frequency device that detects biological information related to heartbeat, respiration, and the like with high accuracy. A high-frequency device (1) includes a biological signal extracting unit (heartbeat signal extracting unit 53, respiration signal extracting unit 63) that extracts a biological signal representing a specific frequency component; and an autocorrelation function processing unit (heartbeat autocorrelation function processing unit 54, respiratory autocorrelation function processing unit 64) that determines periodicity of an autocorrelation function to calculate biological information..

Health monitoring device

A computer-implemented method for processing ecg data may include: receiving ecg data representing a plurality of heartbeats; analyzing the ecg data to determine whether each of the plurality of heartbeats is a normal heartbeat or an abnormal heartbeat; associating each of the abnormal heartbeats with an existing template or a new template; receiving input related to each new template, wherein the input includes either: a) a confirmation that the new template represents an abnormal heartbeat, or b) a reclassification of the new template as representing a normal heartbeat or a different abnormal heartbeat; and in response to the user input, updating a label of each of the heartbeats associated with each confirmed new template and each of the heartbeats associated with each reclassified new template.. .

Secure labeling of network flows

An enterprise security system is improved by instrumenting endpoints to explicitly label network flows with cryptographically secure labels that identify an application or other source of each network flow. Cryptographic techniques may be used, for example, to protect the encoded information in the label from interception by third parties or to support cryptographic authentication of a source of each label.
Sophos Limited

Exercise suit with integrated weights

An exercise suit with integrated weights includes a shirt portion and a pants portion that are constructed from a lightweight elastomeric material. A plurality of soft weights are disposed along the shirt and pants portions at locations adjacent to the major muscle groups of the suit wearer.

Methods for inhibiting stenosis, obstruction, or calcification of a stented heart valve or bioprosthesis

Methods for inhibiting stenosis, obstruction and/or calcification of a heart valve following implantation in a vessel having a wall are disclosed. In one aspect the method includes providing a bioprosthetic heart valve mounted on an elastical stent; treating the bioprosthetic heart valve with a tissue fixative; coating the stent and the bioprosthetic valve with a coating composition including one or more therapeutic agents; implanting the bioprosthetic valve into the vessel in a diseased natural valve site; eluting the coating composition from the bioprosthetic valve; and inhibiting stenosis, obstruction and/or calcification of the bioprosthetic heart valve by preventing the attachment of stem cells to the bioprosthetic heart valve, the stem cells circulating external and proximate to the bioprosthetic heart valve by activating nitric oxide production (i) in the circulating stem cells, (ii) in an endothelial cell lining covering the bioprosthetic heart valve tissue, (iii) or both..
Concievalve Llc

Replacement heart valve with improved stitching

A replacement heart valve implant may include an expandable anchor member, a plurality of valve leaflets disposed within the anchor member, a seal member disposed about a distal portion of the anchor member, one or more whip sutures attaching a distal end of the seal member to a distal end of the plurality of valve leaflets at a joint, one or more distal lashing sutures attaching a distal portion of the seal member to a distal end of the anchor member, and a plurality of proximal lashing sutures attaching a proximal portion of the seal member to the distal portion of the anchor member, wherein the one or more distal lashing sutures does not extend through the seal member.. .
Boston Scientific Scimed, Inc.

Medical alert system

A medical alert system comprises a wearable heart monitoring device for transmitting wireless heart rate data signals to a portable computing device. A processor associated with the portable computing device processes the heart rate data signals to determine whether the signals meet pre-established triggering criteria.

Quantitative heart testing

heart condition and function can be quantified using repolarization measures and/or repolarization indices derived from a time-frequency transform of an electrocardiogram, e.g., based on points in time associated with the t wave. The electrocardiograms, time-frequency maps derived therefrom, and/or indices obtained by analysis of the time-frequency maps and electrocardiograms may be assembled into a user interface.
Heart Test Laboratories, Inc.

Managing connections for data communications using heartbeat messaging

A system, computer-implemented method and computer program performs heartbeat messaging for managing connections for data communications. In one example method, an indication of a problem associated with a connection for data communication in a computing system or network is received.

Managing connections for data communications using heartbeat messaging

A system, computer-implemented method and computer program performs heartbeat messaging for managing connections for data communications. In one example method, an indication of a problem associated with a connection for data communication in a computing system or network is received.

Device cloud monitoring and stability

An example system may include a first device connected over respective communications interfaces to a plurality of second devices. The first device may establish respective remote terminals between the first device and one or more second devices.

Methods and compositions for treating age-related disorders

The present invention relates to methods and compositions containing an antagonist of a negative regulator of gdf-11 (e.g., an antibody) for use in treating an age-related condition. In particular the methods and compositions can be used to treat an age related cardiovascular condition such as diastolic heart failure..

Fine resolution identification of a neural fulcrum for the treatment of chronic cardiac dysfunction

Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone.

Implantable neurostimulator-implemented managing tachyarrhythmic risk during sleep through vagus nerve stimulation

A patient suffering from congestive heart failure is at increased risk of cardiac arrhythmogenesis during sleep, particularly if experiencing central sleep apnea as a co-morbidity. Low intensity peripheral neurostimulation therapies that target imbalance of the autonomic nervous system have been shown to improve clinical outcomes.

Blood pump

A blood pump has a hollow body in which an impeller with a spiral blading produces an axial propulsion of blood along the impeller, as well as an at least partly actively stabilized magnetic bearing device and a hydrodynamic bearing device for the impeller. The impeller may be set into a rotation about a rotation axis of the impeller with a motor stator located outside the hollow body.

Centrifugal pump for medical use and artificial heart assist device having centrifugal pump for medical use

A centrifugal pump includes a rotating shaft, a pump substrate, a housing and an impeller. The pump substrate has a driving unit configured to rotate the rotating shaft.

Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin

The present application provides methods for treating cardiovascular conditions. The methods can include administering a transient receptor potential vanilloid 1 (trpv1) receptor agonist to an epidural space.

Percutaneous heart valve prosthesis

A percutaneous heart valve prosthesis (1) has a valve body (2) with a passage (9) extending between the first and second ends (7, 8) of the valve body (2). The valve body (2) is collapsible about a longitudinal axis (10) of the passage (9) for delivery of the valve body (2) via a catheter (18).

Methods of packaging and delivering prosthetic heart valves

An improved holder and storage system for prosthetic heart valves that pre-shields or pre-constricts the commissure posts of the valve to prevent suture looping. Pre-shielding and pre-constriction mean at the time of manufacture, so that the valves are stored with the commissure posts shielded and/or constricted.

Leaflet suturing to commissure points for prosthetic heart valve

A collapsible prosthetic heart valve includes a collapsible and expandable stent and a collapsible and expandable valve assembly. The stent has a proximal end and a distal end.

Methods for quickly implanting a prosthetic heart valve

A heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The prosthetic valve has a base stent that is deployed at a treatment site, and a valve component configured to quickly connect to the base stent.

Collapsible prosthetic heart valves

A prosthetic heart valve includes a collapsible and expandable support frame extending between an inflow end and an outflow end and a plurality of commissures, wherein each commis sure is formed with an elongate opening. A plurality of leaflets are supported inside the support structure and operative for allowing flow in a first direction from the inflow end to the outflow end and to substantially block flow in an opposite direction from the outflow end to the inflow end.

Angiogenic treatment of ischemic heart disease

Devices, methods, systems and procedures for localized, targeted treatment of angiogenic-based therapy in at least one region of interest in one or more layers of cardiac tissue. Various methods can include diagnosing a patient with ischemic heart disease or “at-risk” of manifesting ischemic heart disease, placing the patient into a specific angiogenic-based treatment therapy group, collecting image data, confirming image data and other diagnostic test results, developing a preoperative plan to target region of interest, inserting the catheter into a heart chamber, monitoring the distal end of the catheter tip within the heart on a visual display, contacting at least one layer of cardiac tissue, creating one or more channels in the heart tissue and/or administering the angiogenic-based therapy..

Genetic polymorphisms associated with cardiovascular diseases, methods of detection and uses thereof

The present invention provides compositions and methods based on genetic polymorphisms that are associated with cardiovascular diseases, particularly coronary heart disease (especially myocardial infarction) or hypertension. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection..
University Of Texas Board Of Regents

Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease

The invention relates to pimobendan for use in a method of reducing the heart size and/or delaying the onset of clinical symptoms in a patient suffering from asymptomatic (occult, preclinical) heart failure, preferably congestive heart failure, due to mitral valve disease (mvd), and/or delaying the onset of heart failure, preferably congestive heart failure, in a patient suffering from asymptomatic (occult, preclinical) heart failure, preferably congestive heart failure, due to mitral valve disease (mvd), wherein the patient is preferably a mammal, more preferably a human, a dog, a cat or a horse, and most preferably a dog.. .
Boehringer Ingelheim Vetmedica Gmbh

Trans-aortic delivery system with containment capsule centering device

heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly which can include a first control mechanism, a second control mechanism, and a decoupling mechanism.
Medtronic Vascular Galway

Heart valve prosthesis

A heart valve prosthesis (1), including: a stent framework (2), which can be transferred from a collapsed state into an expanded state, in which the stent framework (2) extends along an axis (a′), wherein the stent framework (2) has a plurality of struts (20, 24), which form a plurality of cells (21a, 21b, 25) connected to one another; and a heart valve (3), which is fixed to the stent framework (2). In accordance with the invention, the thickness (d′) of the struts varies in the peripheral direction (u) of the expanded stent framework (2)..
Biotronik Ag

Thorascopic heart valve repair method and apparatus

An instrument for performing thorascopic repair of heart valves includes a shaft for extending through the chest cavity and into a heart chamber providing access to a valve needing repair. A movable tip on the shaft is operable to capture a valve leaflet and a needle is operable to penetrate a capture valve leaflet and draw the suture therethrough.
Mayo Foundation For Medical Education And Research

Detection apparatus, detection method, and program

There is provided a detection apparatus including: a heartbeat sensor that includes a plurality of electrodes and is configured to detect a first detection signal indicating heartbeat of a detection target via the plurality of electrodes; a pulse wave sensor configured to detect a second detection signal indicating a pulse wave of the detection target; and a processing unit configured to detect a pulse of the detection target on the basis of the first detection signal and the second detection signal.. .
Sony Mobile Communications Inc.

Polygraph

A method comprising measuring skin conductivity level of a human subject responsive to a series of preliminary questions; measuring skin conductivity level of the human subject in response to a series of control questions; and in case that a sympathetic activation is detected, finding the authenticity of the response to the control question by comparing the recovery time of skin conductivity level for the control question with the basic recovery time. Further, a method comprising measuring heartbeat of a human subject responsive to a series of preliminary questions to which the answer is known, to derive a level of coherence of the heartbeat being a baseline heartbeat coherence level; presenting the human subject with a series of control questions, and finding the authenticity of a response to a relevant question by comparing the heartbeat coherence detected with the baseline heartbeat coherence and the unbalanced heartbeat coherence..
Reflection Technologies Ltd.

Method and device for managing instant communication application program, and mobile terminal thereof

A method and device for managing an instant communication application program, and a mobile terminal thereof are provided. The method includes: when an upper-layer application processor (ap) side of a mobile terminal is in a standby state, an instant communication application program is prevented from sending a heartbeat packet to a network server through the upper-layer ap side; and the instant communication application program is replaced to send the heartbeat packet of the instant communication application program to the corresponding network server..
Zte Corporation

Method for heartbeat packet processing by using proxy, apparatus, and communications system

The embodiments of the present invention provide a method for heartbeat packet processing by using a proxy, an apparatus, and a communications system. The method includes: receiving, by a host, a first heartbeat packet sent by a first application in a client, where the client is a terminal that accesses the host by using a short range communications technology; and determining, by the host according to the first heartbeat packet and a first preset list, whether the first application is included in the first preset list.
Huawei Technologies Co., Ltd.

Left heart vent catheter

A method for venting the left ventricle of a patient's heart includes the step of providing a left heart vent catheter that includes an elongate tube having a hollow passageway. The catheter is provided with a plurality of openings and a balloon near the distal end.

Apparatus for performing peritoneal ultrafiltration

An apparatus for ultrafiltration of a patient being overhydrated due to congestive heart failure, comprising a tube set including a connector for connection to a patient line for access to the peritoneal cavity of the patient. A flow pump is arranged for addition and removal outflow and inflow (recirculation) of fluid from/to the peritoneal cavity.
Triomed Ab

A device for generating bilateral pressure impulses

Disclosed is an electromechanical device generating bilateral pressure impulses, wherein the alternative and specular movement of the homologous cursors (cv, co), pacing one of the cartesian axes, exclusively manages mobile cores (nem) of electromagnets (em) with planned solicitation, for supplying the necessary mechanical energy for the correct working of operating machines of different kinds, and in particular of a permanent artificial heart.. .

Chelator-targeting ligand conjugates for cardiovascular imaging

Disclosed are methods of imaging a site in a heart of a subject to detect cardiovascular disease that involve stressing a subject, administering to the stressed subject an effective amount of a radionuclide-labeled chelator-glucose analog conjugate, and imaging the heart of the subject by detecting a signal generated by the conjugate in the heart of the subject. Also disclosed are methods of imaging a peripheral blood vessel in a subject by using a detectable amount of a radionuclide-labeled chelator-glucose analog conjugate.
Cell>point, Llc

Methods of implanting a cardiac implant with integrated suture fasteners

A cardiac implant system including a cardiac implant such as an annuloplasty ring, a prosthetic heart valve, or a valved conduit pre-assembled at the time of manufacture with devices for securing the implant to a heart valve annulus using knotless suture fasteners. The knotless suture fasteners may be embedded within a pliant sealing edge of the cardiac implant, or they may be positioned adjacent to the sealing edge.
Edwards Lifesciences Corporation

Method for treating an aortic valve

A method of implanting a prosthetic heart valve includes advancing the prosthetic heart valve in a radially-contracted configuration into an annulus of a native aortic valve. The prosthetic heart valve includes a self-expanding body and a plurality of leaflets fastened to the body.
Edwards Lifesciences Corporation

Surgical heart valves adapted for post-implant expansion

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander..
Edwards Lifesciences Corporation

Expandable surgical heart valve indicators

A prosthetic heart valve configured to replace a native heart valve and for post-implant expansion and having a valve-type indicator thereon visible from outside the body post-implant. The indicator communicates information about the valve, such as the size or orifice diameter of the valve, and/or that the valve has the capacity for post-implant expansion.
Edwards Lifesciences Corporation

Heart valve prosthesis

Mitral valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.
Medtronic, Inc

Spacer for securing a transcatheter valve to a bioprosthetic cardiac structure

A spacer for creating a docking station for a transcatheter heart valve is provided. The spacer changes an effective diameter and/or a shape of an implanted bioprosthetic structure such as a bioprosthetic heart valve or annuloplasty ring, providing a supporting structure into which the transcatheter valve expands without over expanding.
Edwards Lifesciences Corporation

Dual sterilization containment vessel

The disclosure pertains to a vessel for holding replacement heart valves and associated positioning and installation apparatus which is configured and adapted to contain a biocidal sterilization fluid during and following exposure of a delivery system for the replacement heart valve to sterilization by ionizing radiation and methods of use therefor. The vessel includes a shield which limits exposure of biologically derived material therein to radiation.
Boston Scientific Scimed Inc.

Femoral drape

A sterile femoral drape intended to be placed over a surgical patient lying on an operating table to isolate the patient during the surgical procedure, the drape comprising a top sheet of bio-impermeable material of a length and width greater than a conventional operating table such that the top sheet fully encompasses the patient and drapes over the lateral side edges and the bottom (foot) edge of the table. Femoral access holes located proximate to the patient's groin are provided to allow access to the patient's femoral artery during heart catheterizations or other surgical procedures.

Methods & systems to determine multi-parameter managed alarm hierarchy during patient monitoring

The present specification discloses systems and methods of patient monitoring in which multiple sensors are used to detect physiological parameters and the data from those sensors are correlated to determine if an alarm should, or should not, be issued, thereby resulting in more precise alarms and fewer false alarms. Electrocardiogram readings can be combined with invasive blood pressure, non-invasive blood pressure, and/or pulse oximetry measurements to provide a more accurate picture of pulse activity and patient respiration.
Spacelabs Healthcare Llc

Closure and ablation of body viscera and conduits

Devices and methods can be used to treat heart conditions. Some such devices include endocardial occlusion and ablation devices.
Mayo Foundation For Medical Education And Research

Heartbeat detection method and heartbeat detection device

A heartbeat detection device includes a difference value calculation unit (3) for calculating, from a sampling data sequence of an electrocardiographic waveform of a living body, one of an amount of change and a degree of change of sampling data for each sampling time, a multiplication unit (4) for calculating, for each sampling time, a product by multiplying one of an amount of change and a degree of change of the sampling data at a time k by one of the sampling data at the time k and sampling data at a time before the time k by a predetermined time t, a peak detection unit (5) for detecting a peak of the product, and a heartbeat time determination unit (6) for setting time of the peak of the product as a heartbeat time.. .
Nippon Telegraph And Telephone Corporation

Monitoring a condition of a subject

Apparatus for monitoring a clinical condition of a subject is described. At least one motion sensor detects motion of the subject and generates a sensed motion signal responsive to the sensed motion.
Earlysense Ltd.

Elisa for vegf

The vascular endothelial growth factor (vegf) activity in a patient's bloodstream or other biological sample can serve as a diagnostic and prognostic index for cancer, diabetes, heart conditions, and other pathologies. Antibody-sandwich elisa methods and kits for vegf as an antigen are provided to detect types of vegf levels in biological samples from animal models and human patients and can be used as a diagnostic/prognostic index..
Genentech, Inc.

Heart valve repair devices for placement in ventricle and delivery systems for implanting heart valve repair devices

Devices and methods for the repair of the functioning of heart valves are provided. A device may comprise a ventricular winding having a generally spiral shape, wherein the device is free of any atrial stabilizing section.
Mitralix Ltd.

Delivery system for prosthetic heart valve

A delivery apparatus for implanting a prosthetic implant in a native lumen of the body includes a handle portion, and a first shaft extending from and movable relative to the handle portion. The first shaft has a proximal end portion coupled to the handle portion and a distal end portion.
Edwards Lifesciences Corporation

Expandable annulus sealing ring for stented minimally invasive heart valve prostheses

The invention relates to a medical implant, comprising an expandable structure (100) which is designed to be expanded from a crimped state into an expanded state, wherein the structure (100) forms a tubular scaffolding in the expanded state, and wherein the structure (100) comprises a plurality of first struts (101) arranged along a periphery of the structure in said expanded state. According to the invention, the first struts (101) each comprise a recess (o), wherein the medical implant (1) further comprises a sealing member (200) arranged in said recesses (o), wherein said sealing member (200) is formed annularly in said expanded state..
Universitat Zurich

Stented prosthetic heart valve having wrap and methods of delivery and deployment

Systems and methods of delivering and deploying a stented prosthetic heart valve having a wrap that is automatically deployed to prevent or mitigate paravalvular leakage. In various embodiments, during transcatheter delivery of the stented prosthetic heart valve, the wrap is extends beyond a stent frame of the stented prosthetic heart valve so that the profile of the stented prosthetic heart valve is not increased during delivery.
Medtronic Vascular, Inc.

Reduced profile prosthetic heart valve

A prosthetic heart valve may include a stent body with a plurality of cells arranged in circumferential rows and a cuff attached to the stent. A leaflet attachment panel may be attached to and span a portion of one of the cells.
Stjude Medical, Cardiology Division, Inc.

Heartbeat packet timer identification method, and device

A heartbeat packet timer identification method and a device, where the identification method is performed by a device that sets a timer, and the method includes determining, in a data packet transmitted by the device, each associated data packet corresponding to each timing end moment of the timer and determining, according to each associated data packet and each timing end moment of the timer, whether the timer is a heartbeat packet timer set by the device for transmitting a heartbeat packet. With reference to a data packet transmitted by a device and each associated data packet that corresponds to each timing end moment of a timer, the heartbeat packet timer identification method and the device may determine with relatively high accuracy whether the timer is a heartbeat packet timer..
Huawei Technologies Co., Ltd.

Client-side fault tolerance in a publish-subscribe system

To provide client-side fault-tolerance in a publish-subscribe system, a message is received on a channel from a server. At a function executing using a processor and a memory, a determination is made whether the message contains a heartbeat data.
International Business Machines Corporation

Method and detecting connectivity

Embodiments of the present invention disclose a method and an apparatus for detecting connectivity. An sdn device transmits a session negotiation packet to a second network element, where the session negotiation packet is used to negotiate a link between a first network element and the second network element, and the first network element is located in an sdn network; the sdn device obtains a response message returned by the second network element to determine that the link is negotiated successfully; and the sdn device transmits a heartbeat packet to the second network element, where the heartbeat packet is used to detect connectivity of the link.
Huawei Technologies Co., Ltd.

System and determining consensus within a distributed database

A system and method for determining consensus within a distributed database are provided. According to one aspect, a protocol is provided that reduces or eliminates heartbeat communication between nodes of a replica set.

Systems and methods for improved detection of processor hang and improved recovery from processor hang in a computing device

Systems and methods are disclosed for improved processor hang detection. An exemplary method comprises setting a timer with a hang threshold value for each of a plurality of processors of a system on a chip (soc).
Qualcomm Incorporated

Compounds, compositions and methods

Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.. .
Cytokinetics, Incorporated

Stimulator, pump & composition

Described is a low voltage, pulsed electrical stimulation device for controlling expression of, for example, follistatin, a muscle formation promotion protein, by tissues. Epicardial stimulation is especially useful for heart treatment.
Calxstars Business Accelerator, Inc.

Pharmaceutical composition, methods for treating and uses thereof

The present invention relates to methods for preventing or treating acute or chronic heart failure and for reducing the risk of cardiovascular death, hospitalization for heart failure and other conditions in patients with preserved or reduced ejection fraction by administering empagliflozin to the patient.. .
Boehringer Ingelheim International Gmbh

Multi-stranded heat set annuloplasty rings

An annuloplasty repair segment for heart valve annulus repair. In one embodiment a multi-stranded cable replaces solid core wire for both the tricuspid and mitral valves.
Edwards Lifesciences Corporation

Leaflet attachment for function in various shapes and sizes

A prosthetic heart valve includes a collapsible and expandable stent and a plurality of commissure features disposed on the stent. A collapsible and expandable valve assembly includes a plurality of leaflets connected to the plurality of commissure features, each commissure feature including a body having a proximal end and a distal end.
St. Jude Medical, Cardiology Division, Inc.

Percutaneously implantable replacement heart valve device and making same

A method of making a replacement heart valve device whereby a fragment of biocompatible tissue material is treated and soaked in one or more alcohol solutions and a solution of glutaraldehyde. The dried biocompatible tissue material is folded and rehydrated in such a way that forms a two- or three-leaflet/cusp valve without affixing of separate cusps or leaflets or cutting slits into the biocompatible tissue material to form the cusps or leaflets.
Colibri Heart Valve Llc

Repositionable heart valve and method

A method for percutaneously replacing a heart valve of a patient. In some embodiments the method includes the steps of percutaneously delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; expanding the anchor to a deployed configuration in which the anchor contacts tissue at a first anchor site; repositioning the anchor to a second anchor site; and deploying the anchor at the second anchor site..
Boston Scientific Scimed, Inc.

System and transcatheter heart valve platform

A method for delivering a platform for reinforcing an annulus of a mitral valve: passing a catheter having a sheath covering a tube formed from a metal into the left atrium, the tube including: an annular portion defining at least one opening, a plurality of upper elements attached to an upper perimeter of the annular portion and extending axially, and a plurality of lower elements attached to a lower perimeter of the annular portion. Inserting the tube into the annulus of the mitral valve; withdrawing the sheath, but leaving the sheath covering the annular portion and the upper elements; bending the lower elements until the lower elements extend radially so as to be positioned beneath the mitral valve; then withdrawing the sheath from covering the annular portion and the upper elements; bending the upper elements until the upper elements extend radially so as to be positioned above the mitral valve..
Abbott Cardiovascular Systems Inc.

Diagnosis support apparatus, operating method, and non-transitory computer readable medium

A diagnosis support apparatus for physiological monitoring includes a data acquisition device for obtaining information of a heartbeat waveform of an examinee. An extractor extracts blood pressure fluctuations based on changes of blood pressure of the examinee from the heartbeat waveform.
Fujifilm Corporation

System and determining consensus within a distributed database

A system and method for determining consensus within a distributed database are provided. According to one aspect, a protocol is provided that reduces or eliminates heartbeat communication between nodes of a replica set.

Device, system, and transcatheter treatment of valvular regurgitation

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.. .
Middle Peak Medical, Inc.

Heart valve leaflet replacement same

A prosthetic heart valve for treatment of a diseased heart valve having native anterior and posterior leaflets that move between an open configuration and a closed position to regulate blood flow through the heart valve during a cardiac cycle of a heart. The prosthetic heart valve having a crescent shaped stent, at least one prosthetic leaflet mounted on an inner surface of the stent, and at least one prong structure coupling a portion of the at least one prosthetic leaflet to a lower ventricular portion of the stent frame.
Dura Biotech

Transcatheter stented prosthetic heart valve delivery devices

Disclosed embodiments and methods provide solutions for coupling and decoupling of a delivery device from a stented prosthetic heart valve with one or more release mechanisms. In situations when one or more sutures get tangled or caught upon attempted retraction of the delivery device and sutures after deployment of the stented prosthetic heart valve, a secondary release mechanism can be provided to sever the suture(s) or release the suture(s) from the delivery device.
Medtronic Vascular, Inc.

Stented prosthetic heart valve having a wrap and delivery devices

Stented prosthetic heart valves comprising a stent frame having a compressed arrangement for delivery within a patient's vasculature and an expanded arrangement for deployment within a native heart valve. The stented prosthetic heart valves including a paravalvular leakage prevention or mitigation wrap that encircles a stent frame and is formed of a flexible material having a variable diameter defined by a greatest distance between the wrap and the stent frame.
Medtronic Vascular, Inc.

Evaluating prosthetic heart valve placement

A method for evaluating the placement of a prosthetic heart valve in a structure of interest. The method comprises acquiring one or more depictions of an anatomical region of interest that includes the structure of interest, wherein each depiction shows the structure of interest and/or the blood pool volume of the left ventricular outflow tract (lvot) of the patient's heart.
Henry Ford Health System

Pericardial modification devices and methods

Devices and methods are described for the treatment of heart conditions such as heart failure with preserved ejection fraction, including diastolic heart failure, by performing a pericardial modification procedure. Intraoperative test procedures for assessing the efficacy of the pericardial modification procedure are also described..
Mayo Foundation For Medical Education And Research

Ultrasonic diagnostic device

A region of interest setting unit sets a region of interest within image data for a tomographic image. The region of interest setting unit sets the region of interest to the heart of an embryo and partitions the region of interest into a plurality of blocks.
Hitachi, Ltd.

Monitoring procedure for early warning of cardiac episodes

Provided are methods and systems for monitoring cardiac function. A series of heartbeat waveforms is collected during a pre-determined time period.
Chronisense Medical Ltd.

Heartbeat detection method and heartbeat detection device

A heartbeat detection device includes a peak search unit (4) for searching for one of a peak at which a value m obtained from a sampling data sequence of an electrocardiographic waveform of a living body changes from an increase to a decrease and a peak at which the value m changes from a decrease to an increase, and a heartbeat time determination unit (5) for checking the value m in a predetermined time domain before a time of the peak and the value m in a predetermined time domain after the time of the peak, and setting the time of the peak as a heartbeat time if differences between the value m at the time of the peak and the values m in the predetermined time domains are not smaller than a predetermined amount.. .
Nippon Telegraph And Telephone Corporation

Method and device for determining and presenting surface charge and dipole densities on cardiac walls

The invention discloses a method, a system, a computer program and a device for determining the surface charge and/or dipole densities on heart walls. Using the foregoing, a table of dipole densities ν(p′, t) and/or a table of surface charge densities ρ(p′, t) of a given heart chamber can be generated..

Intrinsic frequency hemodynamic waveform analysis

Hardware and software methodology are described for cardiac health measurement. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the dicrotic notch.
California Institute Of Technology

Methods and systems for presenting an alert when leaving a direct-mode coverage area

At least one embodiment takes the form of a process carried out by a given mobile radio in a group of mobile radios. The process includes broadcasting heartbeat messages in accordance with a group-wide symmetric-timing protocol and maintaining an in-range list of mobile radios.
Motorola Solutions, Inc

Distributed scheduling systems for digital magazine

A distributed scheduling system is provided for scheduling tasks of providing content items in a digital magazine and verifying completion of tasks performed in a dynamic and scalable way. The distributed scheduling system includes multiple execution devices for executing tasks for generating and presenting the digital magazine, and multiple task service devices for verifying completion of tasks performed by the execution devices.
Flipboard, Inc.

Real-time quality of service monitoring apparatus and method

Provided herein is a real-time qos monitoring apparatus, including an application registration unit configured to register at least one monitoring target application program for qos measurement; a function explorer unit configured to detect user-defined functions in application code of the at least one monitoring target application program; a loop-statement explorer unit configured to detect loop-statements in the application code; a user-defined location explorer unit configured to detect user-defined locations in the application code; and a heartbeat generator configured to generate a plurality of heartbeat calls to correspond to the functions detected by the function finder, the loop-statements detected by the loop finder, and the user-defined locations detected by the user-defined location finder. Accordingly, there are provided a real-time qos monitoring apparatus and method, which may measure qos in real time without additionally modifying the application program..
Electronics And Telecommunications Research Institute

Method for detecting the status of a home automation device

This invention discloses a method of using a cloud server to remotely detect the status of a home automation gateway of a home security and automation network. According to this invention, the home automation gateway of the home security and automation network periodically sends heartbeat packets to a cloud server.
Wireless Input Technology, Inc.

User identification via motion and heartbeat waveform data

The disclosure relates to methods, devices, and systems to identify a user of a wearable fitness monitor using data obtained using the wearable fitness monitor. Data obtained from motion sensors of the wearable fitness monitor and data obtained from heartbeat waveform sensors of the wearable fitness monitor may be used to identify the user..
Fitbit, Inc.

Apparatus and methods for improving health outcomes of preterm infants

Adverse effects of pain in a premature infant, especially a very or extremely premature infant may be ameliorated by exposing the infant to stimuli comprising one or more of vertical oscillating motion simulating breathing, skin contact with an interface that mimics human skin and exposure to sounds and/or vibrations that simulate heartbeats. A device including a movable platform provides such stimuli within a neonatal intensive care incubator.
British Columbia Cancer Agency Branch

System for testing valves

This document provides systems and methods for testing of various kinds of valves. For example, this document provides systems and methods for accelerated life testing of prosthetic heart valves..
Ta Instruments-waters L.l.c.

Annuloplasty repair devices, systems and methods

An annuloplasty prosthesis and delivery system for implanting the prosthesis adjacent an annulus of a heart valve having leaflets for adjusting the annulus to improve valve function includes a ring prosthesis made of shape memory material and having tissue attachment members which attach to the annulus in the atrium and commissural legs extending from the ring between the leaflets and secure against the underside of the valve in the ventricle. The prosthesis is carried via an orientation loop and attaches to the heart tissue such that when the prosthesis is manipulated and relaxed the annulus is adjusted to reduce or eliminate regurgitation..
Serca Biomedical, Llc

Stented prosthesis delivery system having a bumper

Numerous delivery devices for delivery of a stented prosthesis, such as a stented prosthetic heart valve. Various delivery devices include a capsule that is advanced proximally to retain the stented prosthesis, which is secured over an inner shaft assembly of the delivery device.
Medtronic Vascular, Inc.

Apparatus and heart valve repair

A device for gathering tissue of a heart valve leaflet may include an outer tube extending in an elongated direction, a capture tool moveable in the outer tube between a contained position and a use position, and a tissue securing component disposed at a distal end of the outer tube and adapted to be applied to tissue captured by the capture tool and to hold the captured tissue in a gathered configuration. The capture tool may include two grasping members that are moveable relative to one another in the elongated direction.
St. Jude Medical, Cardiology Division, Inc.

Low profile transcatheter heart valve

A method of crimping an implantable prosthetic valve can include placing protective material over at least a portion of the implantable prosthetic valve. The protective material can be configured to occupy space between open cells of a frame of the implantable prosthetic valve to prevent damage to a leaflet structure of the implantable prosthetic valve.
Edwards Lifesciences Corporation

Heart valve prosthesis for controlled thrombus development

The invention relates to a heart valve prosthesis including a heart valve a main body for supporting the heart valve. The heart valve includes a terminating material selected from material and configured to at least partially close a paravalvular leak by controlled thrombus development..
Biotronik Ag

Self-centering guide catheter

An example medical device is disclosed. The device includes a tubular member having a lumen defined therein and a distal end portion, the distal end portion defining a guidewire port.
Mayo Foundation For Medical Education And Research

Device for heart repair

A catheter device for repair of the heart by implanting an artificial chord is disclosed. The device comprises a leaflet anchor 10 for placement in a leaflet 12 of a heart valve, wherein the leaflet anchor 10 is arranged to be coupled to the artificial chord 14; and a mechanical gripper device 6 for grasping the leaflet 12 of the heart valve, wherein the gripper device 6 comprises a leaflet anchor channel for housing the leaflet anchor 10 in a folded configuration; the gripper device 6 and leaflet anchor 10 being arranged such that when, in use, the gripper device 6 grasps the leaflet 12, the leaflet anchor 10 can be pushed out of the leaflet anchor channel to pierce the leaflet 12 and form the leaflet anchor 10 into an unfolded configuration so that hooked formations of the leaflet anchor 10 can, in use, secure the leaflet anchor 10 in the leaflet 12..
Cardiomech As

Ultrasonic diagnostic apparatus and image processing method

An ultrasonic diagnostic apparatus according to an embodiment includes a processing circuitry. With respect to pieces of image data of a plurality of cross sections passing through the heart of a subject that have been collected by ultrasonically scanning each of the cross sections for a period of at least one heart beat, the processing circuitry performs tracking processing including two-dimensional pattern matching to generate pieces of analysis information in each of which a cardiac wall motion of the heart in each section is analyzed.
Toshiba Medical Systems Corporation

Analyzer

An analyzer in an embodiment includes processing circuitry. The processing circuitry identifies at least a part of a contour of a heart of a subject for an image corresponding to a first cardiac time phase and an image corresponding to a second cardiac time phase that are included in time-series images including the heart of the subject.
Toshiba Medical Systems Corporation

Biological information measuring device

A biological information measuring device includes: a pulse wave sensor unit which detects a pulse wave of a living body and outputs a pulse wave signal; an mcu which generates heart rate information and time information; a storage unit capable of storing the heart rate information; operation buttons which output an operation signal corresponding to an input operation by a person; and a display unit. The mcu displays the time information on the display unit in a time display mode, writes the heart rate information in the storage unit in a measuring mode, and displays the heart rate information on the display unit without writing the heart rate information in the storage unit in a heartbeat display mode.
Seiko Epson Corporation

Novel device and method to measure ventricular arterial coupling and vascular performance

A device and method for analyzing of a disturbed pattern of pulse wave front results in a non-invasive, real-time diagnostic tool of arterial vascular performance on both a global and regional scale. The device provides a single number quantifying how well the arterial tree as a whole is coupled to receive and distribute a stroke volume of a single heartbeat.
The Johns Hopkins University

Lease-based heartbeat protocol method and apparatus

A lease-based heartbeat protocol method is provided. The method may include sending a heartbeat request to a server device in a lease period, and receiving a heartbeat request response from the server device; and determining a retry sending at adaptive interval in response to the heartbeat request response being abnormal, and sending a retry heartbeat request to the server device again after the retry sending interval is past, until the lease period expires or a corresponding heartbeat request response is normal.
Alibaba Group Holding Limited

System and accelerated angiographic magnetic resonance imaging

A magnetic resonance method and system are provided for projection mr imaging of vascular structures within a subject, with scan times that are shorter than those needed for conventional techniques. Image acquisition sequences are synchronized with heartbeat cycles of the subject, and are configured to generate image data having a reduced spatial resolution in the projection direction perpendicular to a preselected projection plane.
Northshore University Healthsystem

Melting furnace for producing metal

In production of a reactive metal using a melting furnace for producing metal having a hearth, ingots can be efficiently produced by efficiently cooling the ingots extracted from the mold provided in the melting furnace. In addition, an apparatus structure in which multiple ingots can be produced with high efficiency and high quality from one hearth, is provided.
Toho Titanium Co., Ltd.

Device, system, and transcatheter treatment of valve regurgitation

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation enhancement element for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, catheter and driver; and a method for transcatheter implantation of a coaptation element across a heart valve.. .
Middle Peak Medical, Inc.

Transapical supplanting an implanted prosthetic heart valve

A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle.
Edwards Lifesciences Corporation

System and cardiac valve repair and replacement

A method of delivering a prosthetic mitral valve includes delivering a distal anchor from a delivery sheath such that the distal anchor self-expands inside a first heart chamber on a first side of the mitral valve annulus, pulling proximally on the distal anchor such that the distal anchor self-aligns within the mitral valve annulus and the distal anchor rests against tissue of the ventricular heart chamber, and delivering a proximal anchor from the delivery sheath to a second heart chamber on a second side of the mitral valve annulus such that the proximal anchor self-expands and moves towards the distal anchor to rest against tissue of the second heart chamber. The self-expansion of the proximal anchor captures tissue of the mitral valve annulus therebetween..

Polymeric heart valve

A polymeric valve which may include a heart valve, and also may include a trileaflet heart valve includes a stent having a base and a plurality of outwardly extending posts from the base and equidistant from each other. A plurality of leaflets each connected to a corresponding one of the posts at one end, and each of the leaflets connected to the base.
The Arizona Board Of Regents On Behalf Of The University Of Arizona

Method and percutaneous delivery and deployment of a cardiac valve prosthesis

Catheter apparatuses and methods are provided for repairing heart valves, particularly mitral valves. The method includes providing a catheter having an elongate, flexible body, with a proximal end and a distal end.
Cedars-sinai Medical Center

Ultrasound diagnosis apparatus and image processing method

An ultrasound diagnosis apparatus includes processing circuitry. The processing circuitry obtains three-dimensional medical image data, taken by using an ultrasound probe, of a region including a heart valve of a patient and a catheter inserted into a heart chamber of the patient.
Toshiba Medical Systems Corporation

Method of measuring the heart rate and respiratory rate of a human being

The invention relates to a method for measuring the human heartbeat rate, comprising the steps of: 1) obtaining a video of the measured subject; 2) parsing the video into a series of image frames; 3) arranging the multiple generated image frames in sequential order; 4) detecting the position of the region of the face in each image; 5) obtaining the facial fluctuation frequency of the measured object according to the change of the position of the face region in the image frame system.. .

Device for measuring human heartbeat rate, respiration rate and body temperature

The utility model relates to a device for measuring the heartbeat, respiration, and body temperature of a human body, comprising of a shell and a base, wherein a pcb board, a buzzer, and a multi-point infrared temperature sensor and a camera are arranged in the shell. The infrared temperature sensor is used for temperature sampling of m×n sampling points, where m≧3, n≧3, and the camera is used for acquiring the video image of the measured object..

Image-analysis for assessing heart failure

An apparatus for assessing heart failure can include an image sensor configured to capture image data of a patient, a sensor configured to capture sensor data for the patient, a memory configured to store the image data and the sensor data, and a processor coupled to the image sensor, the sensor, and the memory. The processor is configured to receive image data in response to detecting a biological condition from the sensor data, wherein the biological condition is indicative of psychophysiological health and cardiac health.
Samsung Electronics Co., Ltd.

System and pacing parameter optimization using heart sounds

A medical device system and associated method predict a patient response to a cardiac therapy. The system includes for delivering cardiac pacing pulses to a patient's heart coupled to a cardiac sensing module and a cardiac pacing module for generating cardiac pacing pulses and controlling delivery of the pacing pulses at multiple pace parameter settings.
Medtronic, Inc.

Staged development devices and methods for transcatheter heart valve delivery

A delivery device for a collapsible heart valve includes an operating handle and a catheter assembly. The operating handle includes a frame defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, and a coupler having locked and unlocked conditions, the coupler being operatively connected to the carriage assembly for movement therewith.
St. Jude Medical, Cardiology Division, Inc.

Heart valves with increased effective orifice area

A prosthetic heart valve for implant in a human. The valve includes a wireform with undulating inflow cusps and outflow commissure posts to which flexible leaflets attach and coapt in a flow area.
Edwards Lifesciences Corporation

Durable high strength polymer composites suitable for implant and articles produced therefrom

Thin, biocompatible, high-strength, composite materials are disclosed that are suitable for use in a valve for regulating blood flow direction. In one aspect, the composite material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as a prosthetic heart valve leaflet.
W. L. Gore & Associates, Inc.

A heart valve treatment device and method

A heart valve therapeutic device has an elongate anchor wherein the anchor has a stiffness to hold its shape and location to support the valve element. The anchor may have a stylet or a shaped or stiff collar arranged to provide a desired shape to the anchor and it may be lockable.

Radiation tomography apparatus and program

There is provided a radiation tomography apparatus comprising: control means for controlling a data collection system to acquire first data by scanning a first scan region centering on a first position in a body axis direction of a subject in synchronization with heartbeats, and second data by scanning a second scan region adjacent to the first scan region and centering on a second position in the body axis direction in synchronization with the heartbeats; and reconstructing means for reconstructing an image of a slice between the first position and second position using the first and second data, the reconstructing means determining a view-angle-range-based use rate for the first data and a view-angle-range-based use rate for the second data according to a position of the slice relative to the first and second positions.. .

Noninvasive monitoring health characteristics

A wearable system and method for providing bcg data from a user including a wearable sensor configured to receive cardiogenic surface vibration waveforms, a calibrating sensor configured to receive cardiogenic center-of-mass (com) vibration waveforms, and a processor configured to use the com vibration waveforms as a template for modifying the surface vibration waveforms to provide health-related outputs. A systematic approach for elucidating the relationship between surface vibrations of the body in the head-to-foot direction from the wearable sensor, and the movements of the whole body as measured by the calibrating sensor is disclosed.
Georgia Tech Research Corporation

Display of temporally aligned heart information from separate implantable medical devices on an extracorporeal display

A cardiac rhythm management system includes a first implantable device such as a defibrillator and a second implantable device such as a leadless cardiac pacemaker. A programmer is configured to receive and display heart data emanating from the implantable defibrillator and from the leadless cardiac pacemaker.
Cardiac Pacemakers, Inc.

Mobile terminal, smart watch, and performing authentication with the mobile terminal and the smart watch

The present invention relates to a mobile terminal and a method capable of performing authentication using a smart watch, including: detecting a request for authentication for executing an application; measuring a user's heartbeat rhythm through a sensor mounted in a bottom of the smart watch when detecting the request for the authentication; and comparing the measured heartbeat rhythm with an already-stored heartbeat rhythm and thus performing the authentication on the application.. .
Lg Electronics Inc.

Heartbeat-based data synchronization apparatus and method, and distributed storage system

A heartbeat-based data synchronization method is disclosed. The method is applied to a distributed storage system, and at least one data block group is stored in the distributed storage system.
Huawei Technologies Co., Ltd.

Biomarker compositions specific to coronary heart disease patients and uses thereof

The present invention relates to a disease-specific metabolite profile, and particularly to a biomarker composition obtained by screening from urine-specific metabolite profiles of coronary heart disease subjects. The present invention also relates to a use of the biomarker compositions in risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease, and to a method for risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease.
Bgi Shenzhen

Cyclic polypeptides for the treatment of heart failure

Or an amide, an ester or a salt thereof, or a bioconjugate thereof, wherein x1, x3, x4, x7, x8, x9, x10, x11, x12 and x13 are defined herein. The polypeptides are agonist of the apj receptor.

Blood circulation system

The preset invention discloses an artificial heart and lung apparatus (100) including a roller pump (120); a blood removal line (101); a first blood transfer line (104); a blood removal rate sensor (111) and a control unit (140) that performs linked control of the roller pump (120) in correspondence with a blood removal rate. The control unit (140) is capable of detecting that the blood removal rate deviates from a blood removal condition set in advance, and out-of-set condition blood removal is performed..
Senko Medical Instrument Mfg. Co., Ltd.

Blood circulation system

Disclosed is an artificial heart and lung apparatus (100) that can be connected to a patient (p), and transfers removed blood to a human body via a roller pump (120), the system including: the roller pump (120); a blood removal line (101) which transfers removed blood to the roller pump (120); a first blood transfer line (104) that transfers blood, which is transferred from the roller pump (120), to the human body; a blood removal rate sensor (111) that is provided in the blood removal line (101); and a control unit (140), in which the control unit (140) performs control such that a blood transfer rate of the roller pump (120) is in a specific range with respect to a blood removal rate measured by a blood removal rate sensor (111).. .
Senko Medical Instrument Mfg. Co., Ltd.

Support stent for transvalvular conduit

Miniature axial flow pumps are implanted inside the heart or major arteries to provide hemodynamic support. These pumps commonly utilize tubular blood conduit tubes to transport blood across the aortic valve.

Apparatus for controlled heart valve delivery

A prosthetic implant delivery assembly can include a prosthetic implant and an elongate catheter. The prosthetic implant can include an expandable stent portion having a longitudinal axis extending from a first end portion of the stent to a second end portion of the stent.
Edwards Lifesciences Corporation

Transcatheter valve with paravalvular leak sealing ring

A prosthetic heart valve includes a collapsible and expandable stent extending from an inflow end to an outflow end and a plurality of prosthetic valve leaflets coupled to the stent. The prosthetic heart valve may also include a sealing ring coupled to the inflow end of the stent, the sealing ring comprising a tube extending circumferentially around the inflow end of the stent.
St. Jude Medical, Cardiology Division, Inc.

Transcatheter prosthetic valve for mitral or tricuspid valve replacement

A prosthesis secures a replacement valve in a heart. The prosthesis includes a radially expandable inflow section and outflow section, and migration blocker rods.
Valcare, Inc.

Replacement heart valve

A replacement heart valve can have an expandable frame configured to engage a native valve annulus. A valve body can be mounted onto the expandable frame to provide functionality similar to a natural valve.
Edwards Lifesciences Cardiaq Llc

Prosthetic heart valve having multi-level sealing member

Embodiments of a prosthetic heart valve are disclosed. An implantable prosthetic valve may be radially collapsible to a collapsed configuration and radially expandable to an expanded configuration.
Edwards Lifesciences Corporation

Prosthetic valve for replacing mitral valve

A prosthetic heart valve includes a collapsible and expandable frame having a main body, an atrial portion, and at least one ventricular anchor. The atrial portion extends radially outwardly relative to the main body and the ventricular anchor extends from a ventricular end of the main body.
Edwards Lifesciences Corporation

Methods of making durable multi-layer high strength polymer composite suitable for implant and articles produced therefrom

A thin, biocompatible, high-strength, composite material is disclosed that is suitable for use in various implanted configurations. The composite material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as heart pacing lead or heart valve leaflet.
W. L. Gore & Associates, Inc.

Devices and systems for docking a heart valve

Expandable docking stations for docking an expandable valve can include a valve seat, one or more sealing portions, and one or more retaining portions. The valve seat can be unexpandable or substantially unexpandable beyond a deployed size.
Edwards Lifesciences Corporation

Sensor information processing apparatus

A filter to cut at least a harmonic component of a frequency component derived from breathing of a person to be observed is applied to a detected signal of a wireless sensor, and a heartbeat component of the person is detected in a signal having passed through the filter.. .
Fujitsu Limited

Physiological sensor delivery device and method

An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve.
Acist Medical Systems, Inc.

Biomarkers for risk prediction of mortality

The present invention relates to a method for predicting the risk of a subject of rapidly progressing to chronic heart failure and/or of hospitalization due to chronic heart failure and/or death. The method is based on the determination of at least one biomarker selected from the group consisting of a bnp-type peptide, igfbp7 (igf binding protein 7), a cardiac troponin, soluble st2 (sst2), fgf-23 (fibroblast growth factor 23), and growth differentiation factor 15 (gdf-15), in a sample of a subject.
Roche Diagnostics Operations, Inc.

Biomarker compositions specific to coronary heart disease patients and uses thereof

The present invention relates to a disease-specific metabolite profile, and particularly to a biomarker composition obtained by screening from blood plasma-specific profiles of coronary heart disease subjects. The present invention also relates to a use of the biomarker compositions in risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease, and to a method for risk assessment, diagnosis, early diagnosis, or pathological staging of coronary heart disease.
Bgi Shenzhen

Flexible smart release tool

A flexible smart release tool enables a control unit at the surface to individually communicate with release tools that are located downhole. The release tools may be individually addressed using a unique logical identifier.
Halliburton Energy Services, Inc.

Method and device for recognising the condition of vehicle occupants

The physical and/or mental condition of a vehicle occupant can be recognized on the basis of a bcg (ballistocardiograph) signal, which is obtained by means of a bcg sensor. The bcg sensor is an mem sensor; a cross-correlation of the bcg signal with heartbeat parameters is carried out in an optimum filter, which heartbeat parameters are varied within predefined limits to find a maximum of the cross-correlation function; and probable peaks are located in a cross-correlation function found in this manner and the heart rate is calculated therefrom..
Ford Global Technologies, Llc

Delivery of cardiac stimulation devices

Some embodiments of an electrical stimulation system employ wireless electrode assemblies to provide pacing therapy, defibrillation therapy, or other stimulation therapy. In certain embodiments, the wireless electrode assemblies may include a guide wire channel so that each electrode assembly can be advanced over a guide wire instrument through the endocardium.
Boston Scientific Scimed, Inc.

Blood circulation system

An artificial heart and lung apparatus includes a roller pump; a blood removal line; a first blood transfer line; a blood removal rate sensor; a control unit that performs the linked control of the roller pump in correspondence with a blood removal rate; and a blood transfer rate adjustment unit that instructs the roller pump to transfer a blood transfer rate. The blood transfer rate adjustment unit includes an operation amount input unit to which an operation amount from an arbitrary circumferential position can be input, and which outputs a pulse signal according to the input operation amount.
Senko Medical Instrument Mfg. Co., Ltd.

Trans-catheter ventricular reconstruction structures, methods, and systems for treatment of congestive heart failure and other conditions

Embodiments described herein include devices, systems, and methods for reducing the distance between two locations in tissue. In one embodiment, an anchor may reside within the right ventricle in engagement with the septum.
Bioventrix, Inc.

Devices and methods for heart valve repair

Devices and methods provide enhanced treatment of a cardiac valve annulus. Methods generally involve contacting an anchor delivery device with the valve annulus and releasing a plurality of coupled anchors from the anchor delivery device to secure the anchors to the annulus.
Guided Delivery Systems, Inc.

Convertible annuloplasty ring configured to receive an expandable prosthetic heart valve

The invention is a cardiac implant, and associated methods therefore, configured to repair and/or replace a native heart valve, and having a support frame configured to be reshaped into an expanded/changed form in order to receive and/or support an expandable prosthetic heart valve therein. The implant may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace/repair a native valve (or other prosthetic heart valve), but to assume a generally non-rigid and/or expanded/expandable form when subjected to an outward force such as that provided by a dilation balloon.
Edwards Lifesciences Corporation

Methods of rapidly deployable surgical heart valves

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures.
Edwards Lifesciences Corporation

Puckering seal for reduced paravalvular leakage

A heart valve assembly includes a heart valve, a self-expandable and collapsible stent, and a sealing member. The stent includes an inflow end and an outflow end and is configured to support the heart valve internally.
St. Jude Medical, Cardiology Division, Inc.

Prosthetic heart valve and method

A system for replacing a deficient native aortic valve includes an implantable prosthetic valve having a self-expandable frame and a valve assembly formed with three valve leaflets. The self-expandable frame includes a plurality of support beams, each support beam having a plurality of preformed bores for allowing the valve assembly to be anchored to the frame at least in part by stitching that extends through the leaflets and through the preformed bores of the support beams.
Edwards Lifesciences Pvt, Inc.

Stents for prosthetic heart valves

A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stem adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.. .
Medtronic, Inc.

Portable measurement of cardiovascular health, system, and method thereof

The disclosure is related to a portable apparatus, and a system for measurement of cardiovascular health, and a method for the same. The portable apparatus is preferably a cuff-less blood pressure device that includes an electrode-based module and a piezoelectric sensor module.
Kentec Inc.

Device group partitions and settlement platform

Device group partitions and a settlement platform are provided. In some embodiments, device group partitions (e.g., partitions of devices based on associated device groups) are provided.
Headwater Research Llc

Shared resource management

Various examples are directed to systems and methods for executing a computing job at a computing node of a distributed computing system. A node controller may receive computing job request data from a system controller.
Red Hat, Inc.

Pregnant abdominal system and associated devices, systems, and methods

Simulated pregnant abdominal systems and associated devices, systems, and methods are provided. The pregnant abdominal systems allow an interactive scenario simulating a routine gestation palpation of a fetal baby, the performance of an external cephalic version as well as the leopold's maneuvers.
Gaumard Scientific Company, Inc.

High definition coloring of heart chambers

A 3-dimensional image is displayed in high resolution colors by generating a 3-dimensional model as a triangular mesh, converting the mesh into a grid of voxels, and assigning attribute values to a portion of the voxels. Laplacian interpolation based on the portion of the voxels is applied for iteratively calculating interpolated attribute values of other voxels.
Biosense Webster (israel) Ltd.

Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders

The invention provides compounds effective as sphingosine-1-phosphate receptor modulators for treatment of cardiopulmonary diseases, such as hypertension (including malignant hypertension), angina, myocardial infarction, cardiac arrhythmias, congestive heart failure, coronary heart disease, atherosclerosis, angina pectoris, dysrhythmias, cardiomyothopy (including hypertropic cardiomyothopy), heart failure, cardiac arrest, bronchitis, asthma, chronic obstructive pulmonary disease, cystic fibrosis, croup, emphysema, pleurisy, pulmonary fibrosis, pneumonia, pulmonary embolus, pulmonary hypertension, mesothelioma, ventricular conduction abnormalities, complete heart block, adult respiratory distress syndrome, sepsis syndrome, idiopathic pulmonary fibrosis, scleroderma, systemic sclerosis, retroperitoneal fibrosis, prevention of keloid formation, or cirrhosis.. .
The Scripps Research Institute

Telescoping catheter delivery system for left heart endocardial device placement

A transseptal catheter delivery system includes an elongate first tubular member and an elongate second tubular member receivable within the first tubular member. The first tubular member includes an adjustable portion adjacent a distal end.
Medtronic, Inc.

Use of ribose for treatment of subjects having congestive heart failure

A method for treating a human subject having congestive heart failure is disclosed herein. An exemplary method includes orally administering a 10 g to 50 g dose of d-ribose daily to a subject having congestive heart failure, wherein the d-ribose is administered in a single dose after fasting, and the administration of d-ribose is continued over a period of time effective to improve cardiac and/or physical function of the subject..
Ribocor, Inc.

Devices, systems, and methods for reshaping a heart valve anulus, including the use of a bridge implant having an adjustable bridge stop

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial adjustability and retrievability years after implant.
Mvrx, Inc.

Systems for placing a coapting member between valvular leaflets

The present invention relates to devices and methods for improving the function of a defective heart valve, and particularly for reducing regurgitation through an atrioventricular heart valve—i.e., the mitral valve and the tricuspid valve. For a tricuspid repair, the device includes an anchor deployed in the tissue of the right ventricle, in an orifice opening to the right atrium, or anchored to the tricuspid valve.
Edwards Lifesciences Corporation

Heart valve anchoring device

The present invention relates to an anchoring device (1) designed for anchoring a prosthetic heart valve inside a heart, comprising an extraventricular part (2) designed to be positioned inside an atrium or an artery and a ventricular part (3) designed to be positioned inside a ventricle, wherein the ventricular part comprises a double wall composed of an outer wall (4) and an inner wall (5) spaced apart at the level where the prosthetic heart valve is intended to be inserted, and wherein the anchoring device further comprises a predefined v-shaped groove (8) formed between the extraventricular part (2) and the ventricular part (3). The present invention also relates to an anchoring system (11) for anchoring a prosthetic heart valve inside a heart, comprising said anchoring device (1), a prosthetic heart valve support (12) and a prosthetic heart valve (13) connected to the prosthetic heart valve support (12)..
Tricares Sas

Heart valve prostheses having multiple support arms and methods for percutaneous heart valve replacement

Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom.
Medtronic Vascular, Inc.





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