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SALE: 390+ Heart-related patent PDFs



 Automated segmentation of organ chambers using deep learning methods from medical imaging patent thumbnailnew patent Automated segmentation of organ chambers using deep learning methods from medical imaging
Systems and methods are disclosed for automatically segmenting a heart chamber from medical images of a patient. The system may include one or more hardware processors configured to: obtain image data including at least a representation of the patient's heart; obtain a region of interest from the image data; organize the region of interest into an input vector; apply the input vector through a trained graph; obtain an output vector representing a refined region of interest corresponding to the heart based on the application of the input vector through the trained graph; apply a deformable model on the obtained output vector representing the refined region of interest; and identify a segment of a heart chamber from the application of the deformable model on the obtained output vector..
The Regents Of The University Of California


 Neurostimulation titration process patent thumbnailnew patent Neurostimulation titration process
Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A titration process is used to gradually increase the stimulation intensity to a desired therapeutic level.
Cyberonics, Inc.


 Systems for establishing supplemental blood flow in the circulatory system patent thumbnailnew patent Systems for establishing supplemental blood flow in the circulatory system
A blood circulation assist system comprising an inflow cannula having a lumen and an insertion device configured to be received therein and to facilitate insertion of a portion of the inflow cannula into a heart chamber. The insertion device includes a shaft having distal and proximal end portions and a plurality of lumens.
Circulite, Inc.


 Systems and methods for providing cardiac electrophysiological markers patent thumbnailnew patent Systems and methods for providing cardiac electrophysiological markers
Systems and methods are provided to detect a multi-domain ecg waveform and display one or more cardiac electrophysiological markers. Electrical impulses are detected between at least one pair of electrodes adapted to be located near a beating heart and are converted to an ecg waveform.

 Exercise device, sensor and  determining body parameters during exercise patent thumbnailnew patent Exercise device, sensor and determining body parameters during exercise
A noninvasive light sensor for detecting heart beat signals has a circular support member engageable circumferentially with a body part of a person. There are a plurality of light emitters and light detectors located around a circumference of the circular support member for respectively emitting light signals into different areas of tissue surrounding the body part, and receiving reflected light signals from the different areas of tissue surrounding the body part..
Well Being Digital Limited


 Sound channel configuration method and apparatus and earphone device patent thumbnailSound channel configuration method and apparatus and earphone device
Embodiments of the present application provide a sound channel configuration method and apparatus and an earphone device. The method includes: obtaining heartbeat transmission signals at two earpieces in pair; and performing sound channel configuration on signals of the two earpieces at least according to the heartbeat transmission signals at the two earpieces.
Beijing Zhigu Rui Tuo Tech Co., Ltd


 Distal tip assembly for a heart valve delivery catheter patent thumbnailDistal tip assembly for a heart valve delivery catheter
A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip.
Medtronic Cv Luxembourg S.a.r.l.


 Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve patent thumbnailTranscatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve
A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly.
Medtronic, Inc.


 Method and device for crimping and loading heart valve patent thumbnailMethod and device for crimping and loading heart valve
A method of crimping and loading prosthetic heart valves comprises folding a crimping sheet to form a spiral wrapped around a heart valve; manually rolling and tightening the spiral to compress the valve inside the spiral; inserting the tightened spiral wrapped around the valve into a cannula; and displacing the valve out of the tightened spiral and into the cannula. A kit for crimping and loading the valve into a delivery device comprises a crimping sheet foldable to form a spiral wrapped around the valve, the spiral manually rollable and tightenable to compress the valve wrapped inside the spiral, so that the tightened spiral is slidably insertable into a lumen of a cannula for delivering the valve; and a plunger sized for insertion into the tightened spiral to displace the heart valve out of the spiral and into the lumen of the cannula..

 Stents for prosthetic heart valves and methods of making same patent thumbnailStents for prosthetic heart valves and methods of making same
A single piece stent construction having a plurality of commissure posts, each of which extends upwardly from a solid ring along a bend line and generally along a central longitudinal axis of the stent.. .
Medtronic, Inc.


Prosthetic mitral or tricuspid heart valve

Said ventricular portion (2v) has a substantially spherical or ovoid shape and comprises anchoring spikes (5v) on the side of said annular portion (2i).. .

Mitral valve assembly

A heart valve assembly has a frame having an anchoring section defined by a plurality of rows of cells, with each cell defined by a plurality of struts that encircle each cell, and a pair of legs extending from the anchoring section. The assembly also includes a leaflet assembly that has a plurality of leaflets that are stitched to the legs.
Horizon Scientific Corp.

Porcine small intestine submucosa leaflet material

A prosthetic heart valve provided herein can include a porcine small intestine submucosa (p-sis) tissue leaflet. The p-sis tissue can include multiple stacked layers that are tensioned and cross-linked to form a material having a thickness of between 50 microns and 0.33 mm.
Boston Scientific Scimed, Inc.

Cultured cell leaflet material

A prosthetic heart valve provided herein can include a cultured cell tissue leaflet. In some cases, a prosthetic heart valve can include a plurality of leaflets secured together and retained within the expandable tubular member.
Boston Scientific Scimed, Inc.

Heart valves prostheses and methods for percutaneous heart valve replacement

Prosthetic heart valve devices and associated methods for percutaneous heart valve replacement are disclosed herein. A transcatheter valve prosthesis configured in accordance herewith includes a frame having a valve support and one or more support arms coupled thereto.
Medtronic Vascular, Inc.

A physiological parameter measuring apparatus is configured to perform a screening for a likelihood of the critical congenital heart disease, based on the oxygen saturations at two locations on a body of a patient and the difference between the oxygen saturations, and to display the likelihood as a result of the screening. The physiological parameter measuring apparatus manages, with respect to each patient, a scheduled time for starting the screening, the result of the screening, and information relating to the patient.
Nihon Kohden Corporation

Enabling application functions responsive to biometric input from more than one person

A method includes running an application on a mobile computing device, the mobile computing device accepting biometric input, and the mobile computing device enabling one or more function of the application only in response to the biometric input indicating that more than one person is present in the same location. Examples of suitable biometric input include a fingerprint, heartbeat, iris scan, facial recognition, and voice recognition.
Lenovo Enterprise Solutions (singapore) Pte. Ltd.

Aav vectors for vascular gene therapy in coronary heart disease and peripheral ischaemia

The invention relates to the provision of a gene therapy for coronary heart disease and peripheral ischemia in mammals. One embodiment is an adeno-associated viral vector (aav vector) comprising a first gene encoding a myocardin-related transcription factor a (mrtf-a).

Pharmaceutical composition and neoangiogenesis/revascularization useful in treating ischemic heart disease

A pharmaceutical composition and a method of treating ischemic heart diseases by growing new blood vessels that supply oxygen and nutrients to infarcted heart tissues throughout the entire infarct zone and for preventing cardiomyocyte apoptosis in ischemic events. The pharmaceutical composition contains an active ingredient compound with a backbone structure of formula (i)..
Lead Billion Limited

Replacement heart valve

A delivery catheter dilates the valve while the frustoconical leaflet support system enables the valve to function (open and close) during the deployment process. Unlike prior prosthetic valves that only allow valve expansion, the valve of the invention may be collapsed if needed in order to re position or retrieve the valve..

Surgical delivery device and use

A delivery device for a stented heart valve comprises a handle, an elongate shaft extending from a distal end of the handle, and a conical housing having a proximal end coupled to the elongate shaft and an open distal end, the conical housing having a conical lumen therein with a first internal diameter adjacent to the proximal end of the conical housing and a larger second internal diameter adjacent to the open distal end of the conical housing.. .
Medtronic 3f Therapeutics, Inc.

Prosthetic valve for replacing a mitral valve

Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion.
Edwards Lifesciences Corporation

Heart valve assembly systems and methods

heart valve assembly systems and methods configured for medical interventional procedures. In one aspect, the methods and systems involve a modular approach to treatment..
Caisson Interventional, Llc

Heart valve assembly comprising twofold sealing

The present invention relates to a heart valve assembly (1000), comprising a frame (1) and a heart valve (100), wherein the frame (1) supports the heart valve (100) or is interconnected thereto, preferably by sewing or sewing alone, the frame (1) comprising at least a first guiding structure (2a) for guiding at least one tension thread (5) for folding and/or unfolding the frame (1) around or along the frame (1), preferably at an outside or an outer circumference of the guiding structure (2a), wherein the heart valve (100), comprises at least two leaflets (101, 101′, 101″); an interconnecting tissue (301) interconnecting the leaflets (101, 101′, 101″) with the frame; wherein the interconnecting tissue (301) or parts thereof, respectively, is interconnected to at least one of the guiding structures (2a, 2b) such that it covers the guiding structure (2a, 2b) or parts thereof at an inner circumference of the guiding structure (2a, 2b) and such that it also covers at least both an upper part (2c) and a lower part (2d) of the outer circumference of the guiding structure (2a, 2b).. .
Venus Medtech (hangzhou), Inc.

Resting heart rate monitor system

It is an object of the present invention to provide a heart rate monitor system (10) which is able to determine the resting heart rate in an effective and unobtrusive manner. In an aspect of the present invention, a heart rate monitor system (10) comprising an inactivity determining unit (320) for determining periods of inactivity (ip) of a user based on motion data (md) detected by at least one motion sensor (200) attached to the user and a resting heart rate calculating unit (330) for calculating a resting heart rate (rhr) of the user based on heart rate data (hr) detected by at least one heart rate sensor (100) attached to the user during the periods of inactivity (ip) as determined by the inactivity determining unit (320) is provided..
Koniniklijke Philips N.v.

Pulmonary hypertension biomarker

Pulmonary hypertension is a progressive disease of various origins that is associated with vascular remodelling and results in right heart dysfunction. Accumulating evidence indicates important roles of immune cells and inflammatory chemokines in the pathogenesis and progression of pulmonary hypertension.
Novartis Ag

Methods for delivery of heart valve devices using intravascular ultrasound imaging

Methods related to delivery of various heart valve implants are described. The implant may be delivered using an ultrasound imaging delivery system.
Millipede, Inc.

Transcatheter pulmonary ball valve assembly

A heart valve assembly has a frame comprising an anchoring section, a generally cylindrical leaflet support section, and a neck section that transitions between the anchoring section and the valve support section. The anchoring section has a ball-shaped configuration defined by a plurality of wires that extend from the leaflet support section, with each wire extending radially outwardly to a vertex area where the diameter of the anchoring section is at its greatest, and then extending radially inwardly to a hub.
Horizon Scientific Corp.

Leaflet in configuration for function in various shapes and sizes

A prosthetic heart valve includes a collapsible and expandable stent having a proximal end, a distal end, an annulus section adjacent the proximal end and an aortic section adjacent the distal end. The heart valve further includes a plurality of commissure features disposed on the stent, and a collapsible and expandable valve assembly, the valve assembly including a plurality of leaflets connected to the plurality of commissure features, each of the plurality of leaflets having a free edge and being configured to have a tension line aligned near the free edge to prevent backflow..
St. Jude Medical, Cardiology Division, Inc.

Subannular sealing for paravalvular leak protection

A prosthetic heart valve for replacing a native valve includes a collapsible and expandable stent extending between a proximal end and a distal end. The stent includes an annulus section adjacent the proximal end and having a first diameter, a plurality of first struts forming cells, and a plurality of second struts connected to the annulus section and forming a plurality of deflecting cells expandable to define a second diameter larger than the first diameter.
St. Jude Medical, Cardiology Division, Inc.

Heart valve with integrated stent and sewing ring

A sewing ring for prosthetic heart valves that is connected and configured to pivot outward. A biocompatible fabric covering surrounds at least a portion of the sewing ring, and the ring may be exclusively connected to a stent with the fabric.
Edwards Lifesciences Corporation

Trileaflet mechanical prosthetic heart valve

A mechanical prosthetic heart valve having a ring, multiple hinges, and multiple leaflets. The hinges are attached to the ring and are evenly spaced from one another along the inner circumference of the ring.
Clover Life Sciences Inc.

Shock wave valvuloplasty with multiple balloons

Described herein are shock wave devices and methods for the treatment of calcified heart valves. One variation of a shock wave device includes three balloons that are each sized and shaped to fit within a concave portion of a valve cusp when inflated with a liquid and a shock wave source within each of the three balloons.
Shockwave Medical, Inc.

Quantitative heart testing

heart condition and function can be quantified using repolarization measures and/or repolarization indices derived from a time-frequency transform of an electrocardiogram, e.g., based on points in time associated with the t wave. The electrocardiograms, time-frequency maps derived therefrom, and/or indices obtained by analysis of the time-frequency maps and electrocardiograms may be assembled into a user interface.

User interfaces for heart test devices

heart condition and function can be visualized and/or quantified using time-frequency maps derived from the time-frequency transform of one or more electrocardiograms. The electrocardiograms, time-frequency maps derived therefrom, and/or indices obtained by analysis of the time-frequency maps and electrocardiograms may be assembled into a user interface.

Application heartbeat period adjusting method and apparatus, and terminal

Embodiments of the present invention disclose an application heartbeat period adjusting method and apparatus, and a terminal, and in the embodiments, it is determined, according to an identifier of an application, that the application is in a heartbeat adjustment blacklist. A first heartbeat period of the application is adjusted to a second heartbeat period according to a preset trigger heartbeat period.
Huawei Device Co., Ltd.

Preparation of (r,r)-fenoterol and (r,r)- or (r,s)-fenoterol analogues and their use in treating congestive heart failure

This disclosure concerns the discovery of (r,r)- and (r,s)-fenoterol analogues which are highly effective at binding β2-adrenergic receptors. Exemplary chemical structures for these analogues are provided.
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv

Methods for renal neuromodulation

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease.
Medtronic Ardian Luxembourg S.a.r.l.

Pneumatically power-assisted tavi delivery system

A delivery device for a collapsible prosthetic heart valve may include an operating handle and a catheter assembly. The handle may include a housing, a piston cylinder, a piston longitudinally slidable within the piston cylinder, the piston and the piston cylinder together defining at least one pressure chamber, a deployment actuator coupled to the housing and rotatable relative thereto, and a pneumatic switch adapted to provide a pressurized fluid to the pressure chamber to apply a longitudinal force to the piston.
St. Jude Medical, Cardiology Division, Inc.

Transapical delivery device and use

A delivery device for a stented heart valve comprises a handle, an inner catheter shaft extending from the handle and having an enlarged bumper element at a distal end, an outer catheter shaft extending from the handle and slidably coupled around the inner catheter shaft, and a retraction mechanism for controlling longitudinal movement of the outer catheter shaft relative to the inner catheter shaft. The outer catheter shaft includes a generally cylindrical housing at a distal end that is structured to receive the bumper element therein..
Medtronic 3f Therapeutics, Inc.

Cylindrical implant and balloon

Disclosed herein are embodiments of a balloon shaped to have one or more enlarged regions to selectively increase expansion forces on an implant. For example, the balloon may have a central portion that is enlarged to exert more force on the center of a stent-mounted prosthetic heart valve.
Edwards Lifesciences Corporation

Staged deployment devices and methods for transcatheter heart valve delivery systems

A delivery device for a collapsible heart valve includes an operating handle, including a frame defining a movement space therein, a carriage assembly moveable within the movement space, and a first resheathing lock having a locked position and an unlocked position. The delivery device further includes a catheter assembly, including a first shaft around which a valve-receiving compartment is defined, the first shaft being fixedly connected to one of the frame or the carriage assembly, and a distal sheath operatively connected to the carriage assembly.
St. Jude Medical, Cardiology Division, Inc.

Apparatus and methods for delivery of prosthetic mitral valve

In some embodiments, a method for delivery and deployment of a prosthetic mitral valve into a heart includes inserting an introducer sheath having a prosthetic mitral valve disposed therein in a collapsed configuration into the left atrium of a patient's heart, through a gap between the native mitral valve leaflets, the left ventricle and apex of the heart. An epicardial pad device coupled to the prosthetic valve via a tether is moved distally out of the sheath.
Tendyne Holdings, Inc.

Collapsible prosthetic heart valves

Prosthetic heart valves, which are collapsible to a relatively small circumferential size for less invasive delivery into a patient and which then re-expand to operating size at an implant site in the patient, include a collapsible/expandable stent-like supporting structure and various components of flexible, sheet-like material that are attached to the supporting structure. For example, these sheet-like other components may include prosthetic valve leaflets, layers of buffering material, cuff material, etc.
St. Jude Medical, Inc.

Multi-layer stent

A collapsible prosthetic heart valve includes a stent and a valve assembly. The stent includes an annulus section and at least one foldable section.
St. Jude Medical, Inc.

Self-expanding heart valves for coronary perfusion and sealing

A prosthetic heart valve includes a collapsible and expandable stent including a plurality of struts forming cells, the stent having a proximal end, a distal end, an annulus section adjacent the proximal end, an aortic section adjacent the distal end, and a transition section disposed between the annulus section and the aortic section, the aortic section having a larger diameter than the annulus section. The heart valve further includes a valve assembly disposed entirely in the annulus section of the stent for controlling the flow of blood through the stent, the valve assembly including a plurality of leaflets, and a cuff, the cuff being disposed on a surface of the stent and extending fully over at least two rows of cells of the stent..
St. Jude Medical, Cardiology Division, Inc.

Stents with anchoring sections

A stent (300, 400, 400′) for a prosthetic heart valve includes a body having an inflow end (310, 410) and an outflow end (312, 412), and an anchoring section (340, 440) adjacent the inflow end. The anchoring section may include structure (342, 344, 420) that extends radially outwardly from the body when the stent is in an expanded condition.
St. Jude Medical, Cardiology Division, Inc.

Unstented heart valve with formed in place support structure

An implantable prosthetic valve has an in situ formable support structure. The valve comprises a prosthetic valve, having a base and at least one flow occluder.
Direct Flow Medical, Inc.

Replacement heart valves and their methods of use and manufacture

A prosthetic valve has a support structure that meets with a plurality of leaflets capable of transitioning between open and closed states. The support structure can include a base frame with a polymer coating and the leaflets can be artificial.
Foldax, Inc.

Heart valve comprising a crown piece interconnected to leaflets, a top cuff and a bottom cuff; and a medical implant

heart valve comprising a crown piece interconnected to leaflets, a top cuff and a bottom cuff; and a medical implant the present invention relates to a heart valve (100), comprising at least two leaflets (101, 101′, 101″); at least one crown piece (111) interconnected to the leaflets (101, 101′, 101″) and intended to be interconnected to a frame (1) of a medical implant or a heart valve assembly; a top cuff (121); and a bottom cuff (131), the crown piece (111), the top cuff (121) and the bottom cuff (131) each being ring-shaped, and each of the top cuff (121) and the bottom cuff (131) being interconnected with the crown piece (111).. .
Venus Medtech (hangzhou), Inc.

Prosthetic valve with sealing members and methods of use thereof

Embodiments of the present invention provide prosthetic valves having sealing members on the external surface thereof. The prosthetic heart valves of the present invention are preferably delivered by catheter directly through the apex of the heart or by other close range transcatheter delivery methods.
Medtronic, Inc.

Fixation band for affixing a prosthetic heart valve to tissue

A prosthetic heart comprising a tube having proximal and distal ends, and a central lumen, a tubular frame having proximal and distal ends, and a central lumen, the tubular frame, comprising a plurality of radially-extending members, being disposed on an outside wall of the tube, the distal end of the tube being everted around the distal end of the tubular frame and extending proximally along the tubular frame and over the radially-extending members, and a valve member attached to the tube.. .
Medtronic, Inc.

Occlusion device for closing an apical hole in the heart wall

A closure device, specifically an occlusion device for heart surgery procedures, e.g., transapical aortic valve implantation, comprises first and second disks (2, 3) having first and second enlarged diameter flange portions (25, 35) adapted to be placed proximate either end of an apical hole in a patient's heart wall, and first and second shoulder portions (20, 30) adapted to be placed within the apical hole near either end. A central waist portion (4) extends between the first and second disks (2, 3) along a center axis (a) of the device and is adapted to extend through the apical hole and interconnect the first and second disks (2, 3), while urging the disks (2, 3) toward one another when in the mounted condition..
Comed B.v.

Drowsiness detection device, drowsiness detection method, and computer-readable recording medium storing program for drowsiness detection

A drowsiness detection device includes a memory; and a processor coupled to the memory and the processor configured to calculate a respiration variation period based on heartbeat interval data which is generated based on data that is obtained from a heartbeat sensor; predict a subsequent period structure of the respiration variation based on the calculated respiration variation period; determine whether or not an abnormal signal is mixed in the heartbeat interval data by comparing the heartbeat interval data during sequential update and the predicted subsequent period structure; and replace the respiration variation period which corresponds to the heartbeat interval data that includes the abnormal signal with the predicted subsequent period structure in a case where it is determined that the abnormal signal is mixed.. .
Fujitsu Limited

Determining a sedentary state of a subject

Various embodiments relate to methods, devices, and systems for ascertaining a sedentary body posture of a subject including: determining if the subject is in a sedentary state when the subject is sedentary for a pre-determined time; receiving a heart rate signal for least one heart rate feature when the subject is in the sedentary state; deriving at least one heart rate feature value when the subject is in the sedentary state further including filtering an arousal value from the received heart rate signal, so as to reduce an influence of the arousal on the determination of the sedentary posture; and determining the sedentary body posture of the subject based on a comparison between the derived at least one heart rate feature value and a pre-determined range associated with the corresponding at least one heart rate feature, wherein for each sedentary body posture, a pre-determined range is stored.. .
Koninklijke Philips N.v.

Simulated environment for transcatheter heart valve repair

An apparatus for applying liquid pressure to resected tissue may include a fixture, a papillary assembly coupled to the fixture and having first and second spaced apart papillary attachment elements, and a resected mitral valve attached to the fixture. The fixture may have a first chamber, a second chamber, and an internal panel extending between the first and second chambers.
St. Jude Medical, Cardiology Division, Inc.





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This listing is a sample listing of patent applications related to Heart for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Heart with additional patents listed. Browse our RSS directory or Search for other possible listings.


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