|| List of recent Graft-related patents
| Textured implant device|
A textured bone graft or implant device includes a spatial member having a number of three dimensional units coupled together, the three dimensional units each include a number of bars coupled together to form a number of openings and to form a porous structure for the spatial member and for allowing the bone materials of the user to be grown and filled into the openings of the textured implant device, the spatial member includes a chamber for engaging with a casing, and the casing includes a compartment for engaging with an inner core, the casing and the inner core each include a number of bars for forming a resilient or flexible or compressible or deformable structure.. .
| Helicoil interference fixation system for attaching a graft ligament to a bone|
The helicoil being mounted on the inserter such that the at least one strut of the helicoil is mounted in the at least one groove of the inserter, such that rotation of the inserter causes rotation of the helicoil.. .
| Methods and devices for surgical guide pin placement|
Methods and devices are provided for placing surgical guide pins, reamers, and ligament grafts into bone. In one exemplary embodiment, the method can include advancing a guide pin that includes a proximal rigid portion and a flexible distal portion.
| Protein based materials, plastic albumin devices and related methods|
Medical devices with a plastic albumin body with a defined three dimensional shape that are particularly suitable for pressure equalization tubes. The plastic albumin body can be a unitary substantially monolithic body of albumin.
| Dual capture device for stent graft delivery system and method for capturing a stent graft|
A delivery system for delivering and deploying stents with proximal and distal apices includes a guidewire lumen, a distal apex release lumen, a proximal apex release lumen, a distal apex capture device and a proximal apex capture device. The distal and proximal apex capture devices include a first distal capture portion and a second distal capture portion fixedly connected to the guidewire lumen and distal apex release lumen, respectively, and a first and second proximal capture portions, respectively.
| Spinous process cerclage for bone graft containment|
A system for fusing a spine comprises a flexion limiting tether having a superior portion, and an inferior portion. The superior portion of the device is coupled to a superior portion of the spine, and the inferior portion of the device is coupled to an inferior portion of the spine thereby constraining flexion of the spine.
| Methods and devices for anchoring a graft to bone|
Methods and devices are provided for anchoring graft to bone. In one exemplary embodiment, a bone cavity is created in bone, a graft is partially advanced into the bone cavity, and a hardenable filler material is inserted into the cavity.
| Device for harvesting, processing, and transferring adipose tissue|
The present disclosure provides devices and methods for harvesting and processing tissue from patients for grafting. The devices can include a tissue collection chamber for ascetically collecting, processing, and/or re-implanting adipose tissue..
| Transvascular access methods|
Various methods employing transvascular access devices are described, including a method of placing a central catheter in a peripheral vein in an arm of a patient; a method of providing percutaneous access to the heart of a patient; a method of clearing a clotted arteriovenous dialysis graft; a method of creating multiple access points into a single blood vessel; a method of creating an av fistula in a patient; and a method of providing a bypass to a blockage in a popliteal artery in a patient.. .
| Assessment and reduction of risk of graft-versus-host disease|
Methods of assessing and reducing risk of graft versus host disease (gvhd) based on gene expression profiling are described, as well as methods of selecting a suitable transplant donor. Corresponding reagents and kits are also described..
| Methods for inducing selective apoptosis|
Provided herein are methods for cell therapy by modifying transfused cells to express an inducible caspase 9 protein, so that the cells may be selectively killed if the patient experiences dangerous side effects. Provided also within relates in part to methods for preventing or treating graft versus host disease by modifying t cells before administration to a patient, so that they may be selectively killed if gvhd develops in the patient..
| Metalizable oriented polypropylene films with a functionalized tie layer material|
Described is a multi-layered film comprising a core layer comprising polypropylene; a metalizable skin layer such as a treated hdpe or petg; and a first tie layer comprising a functionalized polypropylene such as an acid-grafted isotactic polypropylene between the core layer and metalizable skin layer; wherein the metalizable skin layer comprises a polymer having a surface energy (astm d2578) of at least 30 dynes/cm, a young's modulus (astm d790) of at least 1500 mpa, and a melting point (astm d3418) of at least 130° c.; and wherein the film as measured on the metalizable skin side has a haze of less than 1000 haze units, and a gloss of greater than 300 gloss units.. .
| Coated article comprising a hydrophobic anti-reflection surface, and methods for making the same|
Certain examples embodiments relate to hydrophobic anti-reflection coatings, and/or methods of making the same. A major surface of an anti-reflection coating may be treated with a silane-based solution so as to increase the contact angle of the coating's surface.
| Mucus penetrating gene carriers|
Nanoparticles gene carriers, particularly nanoparticle gene carriers which exhibit increased rates of diffusion through cystic fibrosis (cf) mucus, as well as methods of making and using thereof, are described herein. The nanoparticle gene carriers are formed from a nucleic acid complexed to one or more biocompatible, polycationic polymers.
| Core-shell magnetic composite and application on producing biodiesel using the same|
A core-shell magnetic composite is disclosed, which includes: a magnetic core; a shell containing a protective layer and a porous layer, wherein the protective layer is coated on a surface of the magnetic core and the porous layer is the outmost layer of the shell; and a hydrophobic functional group grafted to the shell. In addition, the core-shell magnetic composite can be bound to a lipase to act as a transesterification catalyst.
|Tissue grafts and methods for determining the orientation of a tissue graft|
A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft.
|Placental tissue grafts and improved methods of preparing and using the same|
Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells.
|Surgical method for grafting an artificial implant in a bladder and/or in a urethral or ureteral segment|
A description is given of a method for implanting a prosthesis or artificial implant (100) to a bladder and/or to a urethral/ureteral segment in the surgical treatment of diseases of the bladder and/or of the urethra/ureters by removal of a diseased portion of bladder and/or of urethra/ureters, characterised in that the edge of the prosthesis or artificial implant (100) is interposed between the muscle tissue (5) and the underlying portion of urothelial tissue (6) at the removed bladder portion or at the free ends of the urethra/ureter portions (segments) remaining after removal of the diseased segment, so as to be sandwich sutured between the muscle tissue and the urothelial tissue.. .
|Method and implant device for grafting adjacent vertebral bodies|
A methodology for grafting together adjacent bony structures is provided using an implant device having an endplate with an inner disc portion and outer ring portion spaced from the inner disc portion by a connecting wall disposed therebetween. An endplate interior surface includes a retaining structure for securing the endplate to one of the bony structures, and endplate an exterior surface has an integrally formed socket.
The invention relates to a stent graft comprising a stent (1) having a plurality of ring segments (3) disposed adjacent to one another and connected to one another and at least one membrane (2) having at least one marginal ring segment (4) having a meandering web configuration, wherein web loops (5) which point inwards or outwards are cut in such a way as to produce spring tabs (6) which are disposed so that they engage positively in the web loops (5) and are resiliently movable against the web configuration, wherein the membrane (2) is gripped between the spring tabs (6) and the web.. .
|Drug eluting stent for the treatment of dialysis graft stenoses|
A drug-eluting stent having a first cell pattern at one end and a second cell pattern on an opposite end. The cells in the first cell pattern have a smaller mcusa than those in the second cell pattern.
|Devices and methods for facilitating controlled bone growth or repair|
Bone implantable devices and methodologies permit careful application of biologically active substances and management of bone growth processes. The device includes a body defining a carrier receiving area for locating adjacent bone.
|Minimally-invasive device, kit, and method for harvesting bone graft|
A minimally-invasive bone graft harvesting device, kit, and method are provided. The device includes a hollow cutting element and an extraction element.
|Apparatus for creating graft devices|
An apparatus is provided for applying a restrictive fiber matrix to a conduit to create a graft device. A rotating assembly rotates the conduit, and a polymer delivery assembly delivers the restrictive fiber matrix.
|Compatibilized polypropylene heterophasic copolymer and polylactic acid blends for injection molding applicationscompatibilized polypropylene heterophasic copolymer and polylactic acid blends for injection molding applications|
Injection molded articles and process of forming the same are described herein. The processes generally include providing a polyolefin including one or more propylene heterophasic copolymers, the polyolefin having an ethylene content of at least 10 wt.
|Mimetic peptides derived from collagen type iv and their use for treating angiogenesis- and lymphagiogenesis-dependent diseases|
Mimetic peptides having anti-angiogenic and anti-tumorigenic properties and methods of their use for treating cancer, ocular diseases, such as age-related macular degeneration, and other-angiogenesis-dependent diseases are disclosed. More particularly, active non-cysteine analogs (mimetics), which exhibit anti-angiogenic activity in endothelial cell proliferation, migration, adhesion, and tube formation assays, anti-migratory activity in human breast cancer cells in vitro, anti-angiogenic and anti-tumorigenic activity in vivo in breast cancer xenograft models, and age-related macular degeneration models are disclosed.
|Animal model for the evaluation of the efficacy of an hiv vaccine|
The present invention relates to the use of a severe combined t-b-immune deficient (scid) mouse engrafted with human immunocompetent cells (hu-scid-mouse) as an animal model for the evaluation of the effectiveness of an hiv vaccine. Furthermore, the present invention relates to a method for the evaluation of an hiv vaccine, wherein a hu-scid-mouse of the invention is inoculated with the hiv vaccine and thereafter challenged with hi-virus.
|Pressure sensitive adhesive article|
Disclosed herein is an article including a substrate, a first layer adjacent the substrate, the first layer having a silicone-containing pressure sensitive adhesive and a thickness of less than about 5 um, and a second layer adjacent the first layer and opposite the substrate, the second layer having a pressure sensitive adhesive. The silicone-containing pressure sensitive adhesive can include a copolymer of a vinyl polymeric backbone having polysiloxane moieties grafted thereto..
|Abcb5 positive mesenchymal stem cells as immunomodulators|
The present invention is directed to purified preparations of dermal mesenchymal stem cells that are characterized by the cell surface expression of the abcb5 p-glycoprotein. The cells may be used for any purpose that mesenchymal stem cells from other course are used.
|Methods and compositions for the inhibition of meristematic growth on cucurbit rootstock|
The invention provides methods of inhibiting the growth of a shoot apical meristem of a cucurbit rootstock plant, comprising contacting a shoot apical meristem of the cucurbit rootstock plant with an effective amount of a composition comprising one or more fatty alcohols, thereby inhibiting the growth of the shoot apical meristem of the cucurbit rootstock plant. The present invention further provides methods for preparing and producing cucurbit rootstock plants for grafting and methods for grafting.
|Elephant trunk thoracic endograft and delivery system|
A delivery system for delivering a device within a body lumen. The delivery system includes a self-expanding stent/graft composite prosthesis and a deployment device.
|Automatic fat graft injection device with navigation system|
The present invention relates to a fat graft injection device, which comprises: an injection unit having a connection end and a terminal; the injection unit is operated by robotic arm system in controlled speed, multiple layers, multiple lines, a storage unit connected to the injection unit; and a pump unit connected to the storage unit, wherein the storage unit is between the injection unit and contains fat grafts. Fat grafts in the storage unit are injected into the subcutaneous layer through the injection unit by the pump unit with the guiding of navigation system, thus completing the fat graft injection, with accurate and effective, manner without exhausted back and forth surgeon's arm movement..
|Glycation cross-link breakers to increase resistance to enzymatic degradation|
The present invention relates to a method to treat a grafts, implant, scaffold, and constructs, including allografts, xenografts, autografts, and prosthetics comprising collagen, with an inhibitor of collagen cross-links and/or advanced glycation endproducts (age), in order to alleviate the mechanical weakness induced by the cross-links the invention also provides for kits for use in the operating theater during autograft, allograft or xenograft procedures, or for preparing allograft, xenografts or prosthetics that have not been already treated prior to packaging. The kit comprises a first agent or agents that inhibit collagen cross-links and/or advanced glycation endproducts, instructions for use, optionally a wash or rinse agent, and a device for containing the graft and first agent..
|Rapid drying lacquers containing improved rheology control additive|
This invention relates to rapid drying lacquers that are particularly useful for automotive oem refinish applications. The lacquer includes a novel graft copolymer with segmented (or block) arms as a replacement material for all or part of the cellulose acetate butyrate binder component.
|Thermoplastic resin composition and molded product thereof|
The present invention relates to a thermoplastic resin composition obtained by compounding phosphoric acid and/or monosodium phosphate (d) with a resin composition including a styrenebased resin (a), a graft copolymer (b), and an aliphatic polyester resin (c), wherein the thermoplastic resin composition is excellent in mechanical properties (e.g., impact resistance) and thermal stability, and, in addition, can be molded without any problem in terms of safety and hygiene.. .
|Process for improving the physical properties of bitumen|
Additives may be used to improve certain physical properties of bitumen. The additives are prepared using a formulation comprising: a first component selected from the group consisting of (alkoxylated)-(di or tri)-alkyl phenol-aldehyde (amine) resins; α-olefin-maleic anhydride co-polymers and grafted polymers including half ester/amide and full ester/amide derivatives; and combinations thereof; and a second component which is a synergist and selected from the group consisting of polyamines, amidoamines, imidazolines, and combinations thereof..
|Process for preparing polymers and compositions thereof|
The present invention provides a process for preparing a polymer, employing the steps of: (1) contacting a free radical initiator; a chain transfer agent containing a thiocarbonyl thio group and a free radical leaving group; and a radically polymerisable monomer, to form a polymer chain; and (2) contacting the polymer chain of step (1) with at least one of a polyvalent coupling agent, a polymerisation inhibitor, a grafting acylating agent, an amine and an oil of lubricating viscosity. The invention further provides compositions and uses for the polymer..