This page is updated frequently with new Gly-related patent applications.
|Cleaning composition and methods thereof|
Provided is a cleaning solution and its applications. The cleaning solution comprises a mixture of a basic chemical compound and a solvent solution.
Taiwan Semiconductor Manufacturing Company, Ltd.
|Carbon-metal composite and preparing the same|
The present invention relates to a carbon-metal composite and a method for preparing carbon-metal composite, and more particularly to a method for preparing carbon-metal composite, which: is capable of reducing graphene oxide; which is capable of decreasing the steps and the time for hybridization of graphene which is obtained from the reduction, graphene or carbon nanotube, with metal; which is done under mild condition and; also which is capable of lowering resistivity of the carbon-metal composite. The method for preparing the carbon-metal composite comprises the steps of: reacting a composition containing a carbon compound selected from a group consisting of graphene, graphene oxide and carbon nanotube, a metallic precursor, a reducing agent and a solvent; and removing solvent partially or wholly from the composition reaction-completed.
Dongjin Semichem Co., Ltd.
|Pairing fonts for presentation|
A system includes a computing device that includes a memory configured to store instructions. The system also includes a processor to execute the instructions to perform operations that include attaining data representing features of a font capable of representing one or more glyphs.
Monotype Imaging Inc.
|Biomarkers for epicardial adipose tissue|
A method for predicting the level of epicardial adipose tissue (eat) in a subject comprising: (a) determining a level of one or more lipid biomarkers in a sample from the subject, wherein the biomarkers are selected from the following: (i) phosphatidylcholine (pc) [16:1/16:1] (ii) diacylglycerol (dag) [42:8] (iii) phosphatidylethanolamine-ether (pe-o) [32:5] (iv) phosphatidylcholine (pc) [18:0/22:5] (v) phosphatidylinositol (pi) [18:0/16:1] (vi) phosphatidylglycerol (pg) [20:3/20:3] (vii) phosphatidylglycerol (pg) [22:5/18:1] (b) comparing the levels of the biomarkers in the sample to reference values; wherein the levels of the biomarkers in the sample compared to the reference values are indicative of levels of eat fat in the subject.. .
|Multi-metabolites platform for diagnosis of acute coronary syndrome|
The present disclosure provides a multi-metabolite platform using one or more metabolite selected from a group consisting of tryptophan, homoserine, fatty acid (16:1), fatty acid (18:0), fatty acid (18:1), fatty acid (18:2), fatty acid (22:6), phosphatidylcholine (pc) (34:2), pc (34:3), lysophosphatidylcholine (lysopc) (16:0), lysopc (18:0), lysopc (20:3), lysopc (20:4), lysopc (22:6), monoglyceride (18:1/0:0/0:0) and sphingomyelin (d18:2/16:0) as a biomarker, which can diagnose acute coronary syndrome as well as the symptoms occurring prior to the onset of the disease simply and accurately through in-vivo level analysis.. .
Korea Institute Of Science And Technology
|Microfluidic hplc-chip for glycopeptide analysis with integrated hilic enrichment|
A microfluidic device for glycopeptide analysis includes an enrichment column capable of binding carbohydrates; a trapping column capable of binding peptides, wherein the trapping column is configured to be connected downstream of the enrichment column; a separation column, wherein the separation column is configured to be connected downstream of the trapping column; and a plurality of ports configured to work with a switching device to form a plurality of flow paths, wherein one of the plurality of flow paths allows the trapping column to be in fluid communication with the separation column. A method for glycopeptide analysis using a microfluidic device comprising a trapping column and a separation column, the method includes applying a sample of peptides to the microfluidic device; trapping the peptides on the trapping column; eluting the peptides from the trapping column into the separation column; and separating the peptides on the separation column..
Agilent Technologies, Inc.
|Recombinant strain of saccharomyces cerevisiae overproducing glycerol|
A truncated version of saccharomyces cerevisiae ivl2 gene encoding a cytosolic form of acetolactate synthase was cloned into an expression cassette under control of a strong constitutive alcohol dehydrogenase (adh1) promoter. The plasmid was introduced into the s.
Archer Daniels Midland Company
|Glyphosate resistant plants and associated methods|
The present disclosure relates to certain polypeptides derived from prokaryotic dgt enzymes, and nucleic acids useful in encoding the same.. .
Dow Agrosciences Llc
|Directed evolution of multivalent glycopeptides that tightly bind to target proteins|
The invention relates to a method for selecting a glycopolypeptide that binds to a target protein, the method including the steps of providing a pool of glycopolypeptides fused via puromycin linker to an encoding mrna-cdna duplex; combining the pool with a target protein to form a mixture; incubating the mixture for a period of time sufficient to allow any target protein to bind to one or more of the glycopolypeptides, thereby forming glycopolypeptide-target protein complexes; and isolating from the mixture the glycopolypeptide-target protein complexes, thereby identifying a plurality of selected glycopolypeptides.. .
The General Hospital Corporation
|Consumer product composition|
A consumer product composition comprises a non-porous dissolvable solid structure comprising from about 30% to about 95%, by weight of the consumer product composition, of a carrier material, and from about 5% to about 50%, by weight of the consumer product composition, of a hydrophobic conditioning agent disposed within the carrier material of the non-porous dissolvable solid structure. The carrier material comprises a polyethylene glycol material, or mixtures thereof, having a molecular weight of from about 200 to about 50,000.
The Procter & Gamble Company
Alkyl acrylate-aromatic vinyl compound-vinyl cyanide compound copolymer with improved low-temperature impact strength and polycarbonate composition comprising the same
Disclosed are an alkyl acrylate-aromatic vinyl compound-vinyl cyanide compound copolymer which is prepared using a polyalkylene cross-linking agent such as polyethylene glycol diacrylate or polyethylene glycol dimethacrylate for a core of the alkyl acrylate-aromatic vinyl compound-vinyl cyanide compound copolymer and thus advantageously improves low-temperature impact strength of resins when the copolymer is applied to a polycarbonate resin composition, and the polycarbonate resin composition comprising the copolymer.. .
Lg Chem, Ltd.
Multivalent glycopeptides that tightly bind to target proteins
The invention relates to a glycopolypeptide that includes one or more modified amino acid residues having a sidechain comprising a monosaccharide or an oligosaccharide, wherein the glycopolypeptide binds specifically to a carbohydrate-binding monoclonal antibody with an affinity of less than 100 nm. Immunogenic conjugates that include the glycopolypeptide, and pharmaceutical compositions that include the glycopolypeptide or the immunogenic conjugate are also disclosed.
Methods for modulating mannose content of recombinant proteins
The present invention relates to methods of modulating (e.g., reducing) the mannose content, particularly high-mannose content of recombinant glycoproteins.. .
Production of recombinant lubricin
Disclosed are new recombinant isoforms of human-like lubricin or prg4 glycoprotein having outstanding lubrication properties and a novel glycosylation pattern, and methods for their manufacture at high levels enabling commercial production.. .
Glycopeptide compositions and uses thereof
The present disclosure provides glycosylated oligopeptides having the sequence palmitoyl-x1-lys-x2-x3-lys-x4-oh, where: x1 is: absent, ser having a glycosylated side chain, or asn having a glycosylated side chain; x2 is: thr, thr having a glycosylated side chain, asn having a glycosylated side chain, or ser having a glycosylated side chain; x3 is: thr, or thr having a glycosylated side chain; x4 is: ser, or ser having a glycosylated side chain. At least one of x1, x2, x3 and x4 is an amino acid having a glycosylated side chain.
Sussex Research Laboratories Inc.
Process for the continuous production of ethylene glycol from carbohydrates
A continuous process for converting carbohydrates to ethylene and propylene glycol. The carbohydrates are mixed with water and passed through a reactor at a temperature that hydrolyzes the carbohydrate mixture at least partially to monosaccharides.
Iowa Corn Promotion Board
Compositions and methods for reducing nitrogen volatilization of urea fertilizers
A nitrogen stabilizing composition is provided. The composition includes 10% to 18% w/w n-(n-butyl) thiophosphoric triamide (nbpt), a light oil, an emulsifier, and a solvent including n-methyl-2-pyrrolidone (nmp) and two or more of propylene glycol, ethylene glycol, morpholine and glycerine..
Active Agriproducts Inc.
Method for preparing nano silica and nano calcium carbonate using rice hull ash and flue gas
A method for preparing nano silica and nano calcium carbonate using rice hull ash and flue gas. The method includes: 1) adding rice hull ash to a sodium hydroxide solution, to yield a first mixed solution; stirring and heating the first mixed solution; then filtering the first mixed solution to yield a first filtrate; 2) adding the first filtrate to a reaction still, and diluting the first filtrate; adding polyethylene glycol as a dispersant to the reaction solution; introducing flue gas to the reaction solution; filtering the reaction mixture to yield a first filter cake and a second filtrate; washing the first filter cake to a neural ph, slurrying and drying the first filter cake to yield nano silica; and 3) mixing the second filtrate and a washing solution collected from 2); adding a calcium hydroxide solution to the reaction still, to yield nano calcium carbonate..
Zhongying Changjiang International New Energy Investment Co., Ltd.
Heterogeneous catalyst for transesterification and preparing same
A transesterification catalyst that is heterogeneous and a method for preparing said transesterification catalyst are provided. The catalyst can be used in a variety of transesterification reactor configurations including cstr (continuous stirred tank reactors), ebullated (or ebullating) beds or any other fluidized bed reactors, and pfr (plug flow, fixed bed reactors).
Crystaphase Products, Inc.
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Method for extracting oil from a water and solids composition, the production of ethanol, and ethanol production facility
The present disclosure includes a method for processing a beer stream for the recovery of oil. The method include a step of extracting oil from a beer stream into an organic phase comprising an organic solvent to provide in the organic phase at least a portion of the oil.
Kfi Intellectual Properties L.l.c.
Carboxymethylcellulose polyethylene glycol compositions for medical uses
Compositions and method of manufacturing carboxypolysaccharides (cps) including carboxymethyl cellulose (cmc) and polyethylene glycols (pegs) are provided where the peg is a peg-epoxide covalently linked to the cps. In certain embodiments, the peg attaches to only one cps, forming a decorated cps.
Anionic conjugates of glycosylated bacterial metabolite
The invention relates to anionic conjugates of glycosylated bacterial metabolites that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as glycosaminoglycans (gags). The invention also relates to processes for the preparation of the conjugates.
Glycan Biosciences Llc
Sprayable topical carrier and composition comprising phosphatidylcholine
A pharmaceutical or cosmetic carrier for topical administration substantially consists of phosphatidylcholine, monoglyceride, fatty acid ester of c1-c3 alcohol; volatile solvent selected from ethanol and its combinations with c3-c4 alcohol and/or volatile silicone oil. Also disclosed are pharmaceutical and cosmetic compositions comprising the carrier and pharmaceutically or cosmetically active agent(s)..
Human herpesvirus trimeric glycoprotein b, protein complexes comprising trimeric gb and their use as vaccines
The present disclosure provides modified human herpesvirus glycoprotein b (gb) proteins that incorporate unique mechanisms for generating proteins that mimic their native conformation to enhance their immunogenicity. The modified herpesvirus gb proteins insert a peptide linker at the furin cleavage site in the extracellular domain of herpesvirus gb.
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc.
Prevention of staphylococcus aureus infections by glycoprotein vaccines synthesized in escherichia coli
Provided herein are immunogenic compositions and vaccines for the treatment and prevention of staphylococcus aureus infections. These immunogenic compositions and vaccines comprise combinations of bioconjugates capsular polysaccharides that are n-linked to one or more carrier proteins..
Composition for preventing or treating osteoarthritis
An object of the present invention is to provide a means for preventing or treating osteoarthritis. The present invention provides a composition for preventing or treating osteoarthritis, comprising a fish cartilage water extract containing proteoglycans having molecular weights of not less than 1,800,000..
Cartilage regeneration-promoting agent
It is an object of the present invention to provide a chondrogenesis promoter that is safe and exhibits a chondrogenesis-promoting effect by daily ingestion. It is also an object of the invention to provide a proteoglycan synthesis promoter that exhibits a proteoglycan synthesis-promoting effect by ingestion.
Megmilk Snow Brand Co., Ltd.
Topical solution composition comprising ivermectin
A topical solution composition of ivermectin is provided. The topical solution composition contains a pharmaceutically acceptable alcohol and a pharmaceutically acceptable gelling agent.
Diacylglycerol acyltransferase 2 inhibitors
Compounds of formula i that inhibit the activity of the diacylglycerol acyltransferase 2 (dgat2) and their uses in the treatment of diseases linked thereto in animals are described herein.. .
Long-acting ketoprofen compositions
The invention describes a long-acting veterinary composition comprising at least one ketoprofen ester prodrug. The composition also comprises at least one veterinary acceptable triglyceride, and optionally, at least one preservative, and optionally, at least one additional veterinary acceptable excipient.
Zoetis Services Llc
Fasting mimicking diet (fmd) and glucose lowering drugs protect normal cells and generate cancer sensitizing conditions in response to standard and high glucose conditions induced by rapamycin and dexamethasone
A method for treating a hyperglycemia and hyperglycemia-dependent side effects in a subject undergoing chemotherapy includes a step of identifying a subject undergoing chemotherapy and being administered a hyperglycemia-inducing agent. Short-term starvation or a fasting mimicking diet is administered for a first time period to the subject to prevent hyperglycemia and sensitization to chemotherapy associated with increased glucose levels.
University Of Southern California
Means for lung specific delivery
The present invention is related to composition comprising a lipid composition, wherein the lipid composition consists of a cationic lipid of formula (i) wherein n is any one of 1, 2, 3, and 4, wherein m is any one of 1, 2 and 3, y′ is an anion, wherein each of r1 and r2 is individually and independently selected from the group consisting of linear c12-c18 alkyl and linear c12-c18 alkenyl; a sterol compound, wherein the sterol compound is selected from the group consisting of cholesterol and stigmasterol; and a pegylated lipid, wherein the pegylated lipid comprises a peg moiety and wherein the pegylated lipid is selected from the group consisting of a pegylated phosphoethanolamine of formula (ii) wherein each of r3 and r4 is individually and independently linear c13-c17 alkyl, and p is any integer from 15 to 130; a pegylated ceramide of formula (iii) wherein r5 is linear c7-c15 alkyl, and q is any integer from 15 to 130; and a pegylated diacylglycerol of formula (iv) wherein each of r6 and r7 is individually and independently linear c11-c17 alkyl, and r is any integer from 15 to 130.. .
Silence Therapeutics Gmbh
The invention relates to an oral film made from a copolymer of polyvinyl alcohol and polyethylene glycol and at least one gum. The oral films may further contain a medicated active and a non-medicated component.
Composition comprising collagen peptide, elastin peptide and proteoglycan
A composition that effectively demonstrates a skin beautifying effect, even with low-concentration collagen peptide, can be provided by making the weight ratio of collagen peptide, elastin peptide, and proteoglycan contained in the composition a prescribed ratio.. .
An object of the present invention is to provide a baked confectionery with good aroma, which can maintain its shape and has the crispy texture and is not fragile in spite of having a high oil content. The present invention provide a baked confectionery obtained by using cereal flour, oils and fats, and saccharides as main raw materials, the baked confectionery including the oils and fats by 60 to 120 mass % relative to the cereal flour.
The Nisshin Oillio Group, Ltd.
Retroreflective biodegradable element, composite and related products
A retroreflective element (10) in the form of a micro- or nano-sized prism produced from bio-based and biodegradable plastic polymers, such as polylactic acid (pla) or polyglycolic acid (pga) is provided. A plurality of retroreflective elements (10) are utilized for manufacturing of a reflective composite material (100), which, in turn, may be utilized for manufacturing of a multiplicity of various products.
Waloon Reflector Solutions Oy
System and estimating low-density lippoprotein cholesterol from standard lipid profile
A system and method for estimating a cholesterol associated with low-density lipoprotein are provided. In one aspect, the method includes receiving a lipid profile of a subject, and identifying, from the lipid profile of the subject, a triglyceride concentration and a non-high-density lipoprotein cholesterol concentration.
The present invention generally relates to predicting the risk of developing diabetes in patients who currently do not have diabetes. The invention can involve obtaining a sample from a patient negative for diabetes, conducting an assay on the sample to obtain a level of a glycated albumin, and determining an elevated risk of developing a diabetic condition if said level exceeds a predetermined threshold..
Boston Heart Diagnostics Corporation
Method and kit for detection of microorganism
3) a primer or primers for amplifying a target region of the dna or rna of the microorganism to be detected by a nucleic acid amplification method. The agent for suppressing a nucleic acid amplification inhibitory substance is one or more selected from albumin, dextran, t4 gene 32 protein, acetamide, betaine, dimethyl sulfoxide, formamide, glycerol, polyethylene glycol, soybean trypsin inhibitor, α2-macroglobulin, tetramethylammonium chloride, lysozyme, phosphorylase and lactate dehydrogenase..
Thermophilic and thermoacidophilic biopolymer-degrading genes and enzymes from alicyclobacillus acidocaldarius and related organisms, methods
Isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from alicyclobacillus acidocaldarius are provided. Further provided are methods of at least partially degrading, cleaving, or removing polysaccharides, lignocellulose, cellulose, hemicellulose, lignin, starch, chitin, polyhydroxybutyrate, heteroxylans, glycosides, xylan-, glucan-, galactan-, or mannan-decorating groups using isolated and/or purified polypeptides and nucleic acid sequences encoding polypeptides from alicyclobacillus acidocaldarius..
Battelle Energy Alliance, Llc
Enrichment of oils with polyunsaturated fatty acids
The present invention relates to isolated phospholipid:diacylglycerol acyltransferases (pdat) and polynucleotide sequences encoding the pdat enzymes; polynucleotide constructs, vectors and host cells incorporating the polynucleotide sequences; and methods of producing and using same. Also provided are transformed cells and transgenic plants with enhanced oil accumulation and quality..
Cell separation method using a release system for cell-antibody-substrate conjugates containing a polyethylene glycol spacer unit
The invention is directed to a releasable conjugate comprising a biotinylated ligand having a biotin moiety, a ligand moiety (ligand1) and a biotin-binding molecule (bbm) bound to the biotin moiety of the biotinylated ligand. The ligand moiety of the biotinylated ligand may be separated by a spacer group consisting of polyethylene glycol.
Miltenyi Biotec Gmbh
Modified el188 endolysin sequence
The present invention relates to polypeptides comprising an amino acid sequence exhibiting at least about 90% sequence identity with the sequence of seq id no: 1. Said polypeptides preferably degrade the peptidoglycan of gram-negative bacteria, in particular of pseudomonas and/or campylobacter bacteria.
A freeze-drying encapsulated cells, freeze-dried encapsulated cells, compositions containing freeze-dried encapsulated cells and uses of such cells and compositions
The disclosure provides a method of freeze-drying encapsulated cells, the method comprising at least two consecutive incubation steps, wherein the encapsulated cells are incubated in each incubation step in an incubation solution containing cryoprotectant over a suitable period of time, wherein the concentration of cryoprotectant in the incubation solution is increased with each subsequent incubation step. The disclosure also provides freeze dried cells that are obtained by this method as well as various uses of these cells as pharmaceutical, food additive or additive in cosmetics.
Austrianova Singapore Pte Ltd.
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System of biomimetic energy synthesis
An improved system of generating renewable energy is comprised of a specific configuration of mechanisms, materials, and processes that all function together as a single symbiotic system. In accordance with a preferred embodiment, the system cultivates aquatic biomass, then extracts triglycerides from said biomass.
Removal of unwanted propanol components
The present invention relates to the use of short-path evaporation for reducing from deodorized triglyceride oils the content of propanol components selected from chloropropanols, chloropropanol fatty acid esters, epoxypropanols, epoxypropanol fatty acid esters, and combinations of two or more thereof. It further relates to the use of short-path evaporation wherein further the content of acyl glycerol components is reduced and these acyl glycerol components are selected from diacyl-glycerols, triglycerides with molecular weight in the range below 730 and mixtures of two or more thereof..
Temporary plugging agent for well drilling
A temporary plugging agent for well drilling having a plugging function for a period of not greater than 40 days in a high-temperature environment having a temperature range between 93 and 204° c., and preferably, the above temporary plugging agent for well drilling (optionally formed from two or more types of plugging agents for well drilling) wherein a contained synthetic resin has a ratio of mass loss rate in 80° c. Deionized water relative to the mass loss rate of polyglycolic acid of not less than 0.001 and less than 1, and/or has a compressive strength after a period of not greater than 40 days has elapsed at a temperature range between 93° c.
Provided are polytriglyceride-aag compositions, and corresponding coatings and coated articles. Also provided are methods for preparing the polytriglyceride-aag compositions, and corresponding reagents including β-ketoimide compositions and triglyceride-aag (acetoacetyl group) compositions.
Ohio Soybean Council
Ionizing radiation resistant polycarbonate resin composition and article comprising the same
A polycarbonate resin composition includes: a polycarbonate resin; a polyalkylene glycol compound; and an organic-inorganic hybrid pigment, and has a yellow index (yi) of about −2 to about 4 after irradiation with gamma rays, as measured in accordance with astm d1925 after irradiating an about 3 mm thick specimen with gamma rays at about 25 kgy and leaving the specimen for 7 days. The polycarbonate resin composition can exhibit excellent properties in terms of color and impact resistance after being irradiated with ionizing radiation..
Samsung Sdi Co., Ltd.
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Polycarbonate containing compositions
Polycarbonate-containing compositions having desirable properties, such as good resistance to environmental stress cracking, are achieved using a combination of a polycarbonate polymer, a compatibilizing agent and an olefinic elastomer. The polycarbonate-containing composition may include about 40-98 weight percent of one or more carbonates polymers; about 0.1-10 weight percent of one or more compatibilizing agents; and 0.1-10 weight percent of one or more olefmic elastomers.
Trinseo Europe Gmbh
Photopolymerizable composition, photopolymerizable inkjet ink, and ink cartridge
A photopolymerizable composition, which includes a photoradical polymerization initiator and photopolymerizable monomers containing glycerol dimethacrylate, where an amount of the glycerol dimethacrylate in the photopolymerizable monomers is 25% by mass or greater, and pencil hardness of a cured product is f or harder, where the cured product is formed by curing a coating film through irradiation with light of a wavelength region corresponding to a uva region, with a light to dose of 800 mj/cm2, where the coating film is formed by coating the photopolymerizable composition on a base so as to have an average thickness of 30 μm.. .
Ricoh Company, Ltd.
Carboxylated derivatives of glucosaminoglycans and use as drugs
The invention relates to glucosaminoglycan derivatives, endowed with heparanase inhibitory activity and antitumor activity, bearing carboxylate groups in positions 2 and 3 of at least part of the glucosaminoglycan residues, and to the process for preparing the same. The glucosaminoglycan derivatives of the present invention are generated starting from natural or synthetic glucosaminoglycans, preferably heparin or low molecular weight heparin, optionally 2-o- and 2n-desulfated by two steps of oxidation.
Novahealth Biosystems, Llc.
Tin sulfide quantum dots for in vivo near infrared imaging
An aqueous approach to synthesize capped sns quantum dots (qds) followed by optional capping molecule extension by attaching one or more extending molecules to the capping molecule via peptide bond formation at elevated temperature. The capped sns qds may have a capping molecule:sn:s molar ratio of 16:3:1 to 16:12:1.
Polysubstituted pyrroles having microtubule-disrupting, cytotoxic and antitumor activities and methods of use thereof
The present invention provides polysubstituted pyrrole compounds, pharmaceutically effective salts, prodrugs, solvates and hydrates thereof, having antimitotic, antiproliferative and cytotoxic activity, activity against cells expressing the drug efflux protein, p-glycoprotein, or cells expressing the β-iii isotype of tubulin and antitumor activity. Also provided are methods of utilizing these compounds for inhibiting the proliferation of cancer cells as well as their medical use, in particular for treating cancer, including drug resistant cancer..
The Board Of Regents Of The University Of Texas Sy Stem
Engineered glycoproteins and uses thereof
The present invention provides for novel glycoproteins comprising therapeutically useful polypeptides, or fragments or variants thereof, conjugated to glycosylated amino acid block copolymer polypeptides. These novel glycoproteins possess improved half-life properties as compared to the unmodified therapeutically useful polypeptide.
Aequus Biopharma, Inc.
Use of heptyl glucoside as skin penetration enhancer in transdermal pharmaceutical compositions
The present disclosure refers to heptyl glucoside included, as a natural solubilizer and as a skin penetration enhancer, in transdermal pharmaceutical compositions. Heptyl glucoside is a natural alkyl glycoside and a hydrotrope that improves solubility of active pharmaceutical ingredients (apis), thereby enhancing skin permeability to apis.
Dendritic cell asgpr targeting immunotherapeutics for multiple sclerosis
Methods and compositions for treating multiple sclerosis using dendritic cell anti-asgpr antibodies fused to myelin basic protein or myelin oligodendrocyte glycoprotein provided.. .
Baylor Research Institute
Topical compositions and methods for alleviating or inhibiting symptoms associated with carpal tunnel syndrome, acid reflux, psoriasis, cartilage nodules, fibromyalgia, and diabetes
A composition for, and method of, alleviating or inhibiting one or more symptoms associated with carpal tunnel syndrome, acid reflux, psoriasis, cartilage nodules, fibromyalgia, diabetes, or hypoglycemia in a mammal. The composition includes a fruit-vegetable extract, the composition formulated for contact with the mammal's skin, the fruit-vegetable extract present in an amount effective to alleviate or inhibit one or more symptoms associated with carpal tunnel syndrome, acid reflux, psoriasis, cartilage nodules, fibromyalgia, diabetes, or hypoglycemia in the mammal.
Chimeric vsv virus compositions and methods of use thereof for treatment of cancer
Methods of treating cancer including administering to a subject with cancer a pharmaceutical composition including an effective amount of a chimeric vsv virus are disclosed. The chimeric viruses are based on a vsv background where the vsv g protein is replaced with one or more heterologous viral glycoproteins.
Self-micellizing fatty acids and fatty acid ester compositions and their use in the treatment of disease states
Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect.
Sancilio & Company, Inc.
Sprayable aqueous composition comprising glyceryl trinitrate
The present application relates to a pharmaceutical preparation comprising (a) from 0.15 to 3 weight percent of glyceryl trinitrate, (b) from 40 to 95 weight percent water, and (c1) from 2 to 10 weight percent of at least one water soluble polymer, or (c2) from 1 to 10 weight percent of at least one water soluble polymer and 5 to 20 weight percent of ethanol.. .
G. Pohl-boskamp Gmbh & Co. Kg
Fatty acid treatment for cardiac patients
A method of treating patients in need of treatment for a cardiac disorder has been found which comprises administering to the patient a seven carbon fatty acid compound or derivative thereof, wherein the compound or derivative thereof is able to readily enter the mitochondrion without special transport enzymes. A dietary formulation suitable for treatment of heart tissue in cardiac or surgical patients has been found which comprises a seven-carbon fatty acid chain, wherein the seven-carbon fatty acid chain is characterized by the ability to transverse the inner mitochondrial membrane by a transport mechanism which does not require carnitine palmitoyltransferase i, carnitine palmitoyltransferase ii, or carnitine/acylcarnitine translocase and the ability to undergo mitochondrial β-oxidation, and wherein the compound is selected from the group consisting of n-heptanoic acid or a derivative thereof, a triglyceride comprising n-heptanoic acid or a derivative thereof, and triheptanoin or a derivative thereof..
Baylor Research Institute
Formulation and process for modulating wound healing
R1 to r4 are independent substituents at any available position of the phenyl rings, preferably at 3, 3′, 4, 4′, and/or 5, 5′; and m, n, p, and q are independently 0, 1, 2, or 3 representing the number of substituents of the rings, respectively, but at least one of m or n must be ≧1. Each r1 to r2 is independently selected from substituents described herein, including but not limited to hydroxyl, alkoxy, halo, halomethyl and glycosides.
Mixtures of matter
Suggested is a mixture of matter, comprising: (a) steviol glycosides, (b) starch degradation products and (c) one or more phenolic sweetness-enhancing aroma substances selected from the group formed by hesperetin, phloretin, 1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)propan-1-one, 7,3-dihydroxy-4′-methoxyflavan and 5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2-chromanone. On condition that components (a+b) and (c) are present in a ratio by weight of from 1.99 to 99:1.
Dough for layered cereal flour puffed food, and layered cereal flour puffed food
An object of the present invention is to provide dough for a layered cereal flour puffed food having the soft texture and the good melting mouthfeel while having the crispy texture after the baking, provide a layered cereal flour puffed food obtained by heating and baking the dough, and moreover provide a plastic oil and fat composition suitable in the preparation of the dough. According to the present invention, dough for a layered cereal flour puffed food, including 6 to 20 mass % of triacylglycerol containing one or more kinds of fatty acids selected from caproic acid, caprylic acid, and capric acid as a constituent fatty acid is provided..
The Nisshin Oillio Group, Ltd.
Polymer based transplant preservation solution
Provided are transplant preservation solutions comprising a polyglycerol wherein the polyglycerol is of a molecular weight between about 0.15 kda and about 3.99 kda, methods and uses thereof as well as kits providing said transplant preservation solutions.. .
University Of British Columbia
Television control interface with electronic guide
An on-screen menu method and system for controlling the functions of integrated electronic devices and a television schedule system and method for displaying television schedule information on a television screen includes a program guide having a schedule information area that depicts the programs that are being presented on each channel, at each time during the day and an interconnected series of menus to control the features of the integrated electronic devices. An input device allows the viewer to move a pointer over different interactive areas of the guide and the function performed when the area is activated is displayed in a contextual help window.
Rovi Guides, Inc.
Television control interface with electronic guide
An on-screen menu method and system for controlling the functions of integrated electronic devices and a television schedule system and method for displaying television schedule information on a television screen includes a program guide having a schedule information area that depicts the programs that are being presented on each channel at each time during the day and an interconnected series of menus to control the features of the integrated electronic devices. An input device allows the viewer to move a pointer over different interactive areas of the guide and the function performed when the area is activated is displayed in a contextual help window.
Rovi Guides, Inc.
Template-based methods of making and using ceramic solids and products and devices related thereto
Various embodiments relate to a method comprising forming a template forming a template from a template precursor, wherein the template contains an entrapped ceramic precursor, which can be further processed to form a ceramic solid, such as an oxide ceramic solid. In one embodiment, the template precursor is a hydrogel precursor and the template is a hydrogel template.
Board Of Trustees Of Michigan State University
Compression molded tooth
The compression molded tooth used for practicing dental cutting treatment of the present invention comprises a composition containing a powder or powders of saccharide, polysaccharide, protein, and/or glycoprotein each having a particle size of 1 to 100 μm.. .
Negatively-chargeable toner and manufacturing same
Provided are a method for producing a negatively-chargeable toner that has a narrow particle diameter distribution even when produced by a polymerization method, and a negatively-chargeable toner that is excellent in balance between low-temperature fixability and heat-resistant shelf stability, has fine thin-line reproducibility, and generates little fog, even in high-speed printing. The negatively-chargeable toner includes colored resin particles which contain at least a binder resin, a colorant, a charge control agent and a softening agent, wherein the charge control agent is a copolymer which is obtained by copolymerizing a vinyl aromatic hydrocarbon, a (meth)acrylate and a sulfonic acid group-containing (meth)acrylamide and in which a copolymerization ratio of the sulfonic acid group-containing (meth)acrylamide is 0.8 to 4.0% by mass, and wherein the softening agent is at least one of a monoester compound and a polyglycerol ester compound..
Polyporus squamosus-derived recombinant lectin specific for sialic acid linkage
The present invention relates to a method for producing a polyporus squamosus-derived psl1b recombinant lectin, which binds specifically to sialic acid containing glycoconjugates, from an escherichia coli psl1b strain (deposit number: kctc12507bp) or a pichia pastoris psl1b strain (deposit number: kctc12500bp) and a lectin produced thereby. The recombinant lectin of the present invention can be useful as an active ingredient of a composition or a kit for measuring or detecting glycoproteins, glycopeptides, glycolipids, sugar precursors, or oligosaccharides having sialic acid moieties..
Korea Research Institute Of Bioscience And Biotech Nology