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Gly

Gly-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Methods and compositions for diagnosis and prognosis of renal injury and renal failure
Astute Medical, Inc.
November 30, 2017 - N°20170343562

The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using a plurality of assays, one or more of which is configured to detect a kidney injury marker selected from the group consisting of hyaluronic acid, ...
A method for controlling glycosylation of recombinant glycoprotein
Lg Chem, Ltd.
November 30, 2017 - N°20170342392

The present invention relates to a method for controlling a glycosylation pattern of a recombinant glycoprotein, comprising culturing a cell comprising polynucleotide encoding a recombinant glycoprotein in a culture medium comprising insulin.
O-glycan sialylated recombinant glycoproteins and cell lines for producing the same
Cevec Pharmaceutical Gmbh
November 30, 2017 - N°20170342390

The present invention relates to cell lines that are genetically modified to overexpress a β-galactoside α-2,3-sialyltransferase 1 (st3gal1), preferably human st3gal1, which can be used for the production of recombinant glycoproteins having highly or fully sialylated o-linked galnac glycans (galnac o-glycans), preferably core 1 galnac o-glycans, as well as to respective recombinant glycoproteins. Further, the ...
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Method for manufacturing fungal pharmaceutical composition
Taipei Medical University
November 30, 2017 - N°20170342170

The present invention provides a method for manufacturing fungal pharmaceutical composition, used for extracting a glycosaminoglycan fiber from a fungal cell wall. Differing from the glycosaminoglycan fiber produced by using a fabrication method proposed by taiwan patent no. 442496 showing many drawbacks including low extraction percentage, coarse fiber, and having light-yellow color, the glycosaminoglycan fiber manufactured by using this novel method ...
Anti-glycoprotein iib/iiia antibodies
Biogen Ma Inc.
November 30, 2017 - N°20170342152

Antibodies and antigen-binding antibody fragments that bind to gpiib/iiia and chimeric polypeptides comprising these binding molecules are disclosed. Some of these antibodies and antigen-binding antibody fragments preferentially bind gpiib/iiia on activated platelets while others do not show a preference for binding gpiib/iiia on resting versus activated platelets. Some of these antibodies and antibody fragments do not inhibit ...
Anti-chondroitin sulfate proteoglycan 4 antibodies and uses thereof
The General Hospital Corporation
November 30, 2017 - N°20170342151

Described herein are antibodies that bind chondroitin sulfate proteoglycan 4 (cspg4) and, in particular, chimeric and humanized anti-cspg4 antibodies and fragments thereof. Also provided herein are methods of using individual humanized antibodies or compositions thereof for the detection, prevention, and/or therapeutic treatment of cspg4-related diseases, in particular, melanoma.
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Glycopeptides and uses thereof
Jawaharlal Nehru Centre For Advanced Scientific Research (jncasr)
November 30, 2017 - N°20170342110

The present disclosure provides a compound of formula i or its stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. The present disclosure also relates to process of preparation of vancomycin-sugar conjugates of formula i, its stereoisomers, prodrugs, pharmaceutically acceptable salts thereof, and to pharmaceutical compositions containing them. The compounds of the present disclosure are useful in the treatment, prevention or suppression ...
Novel method for catalytic dehydration of glycerol to acrolein
Zhejiang University Of Technology
November 30, 2017 - N°20170342008

A novel method for catalytic dehydration of glycerol to acrolein is provided. A fixed bed reactor is used, which is placed in a microwave unit. The feedstock is introduced into the fixed bed reactor after being preheated and gasified. Continuous glycerol dehydration occurs in the presence of a microwave-absorbing catalyst in the fixed bed reactor to form acrolein. The microwave-absorbing ...
Foaming agent for building material/binder pastes
Cellcontec Gmbh
November 30, 2017 - N°20170341987

A foaming agent, more particularly for the foaming of a building material/binder paste for producing pory lightweight-construction and insulating materials, is improved in terms of its stability and usefulness at relatively low outdoor temperatures. The foaming agent in the form of an aqueous-organic solution comprises or consists to an extent of at least 85 wt % of the following constituents: a) ...
Polethylene glycol hydrogel injection
Sunbio Inc.
November 30, 2017 - N°20170340774

The present invention relates to a polyethylene glycol hydrogel injection, and, more particularly, to an injection to be administered into a joint (a synovial joint cavity) for the improvement of symptoms of arthritis by containing two separate buffer solutions, wherein a solution (1) contains a polyethylene glycol derivative with an electrophilic functional group and a buffer of ph 3. 5 to 6, and a ...
Contructs for enhancing immune responses
The Wistar Institute Of Anatomy And Biology
November 30, 2017 - N°20170340730

Chimeric protein constructs including a herpesvirus glycoprotein d (gd) and a heterologous polypeptide that interact with herpes virus entry mediator (hvem) and enhance and enhance an immune response against the heterologous polypeptide and methods for their use are provided.
Nanoparticles and their use in cancer therapy
Midatech Ltd
November 30, 2017 - N°20170340665

The present invention provides a nanoparticle comprising a core comprising a metal; and a corona comprising a plurality of ligands covalently linked to the core, the plurality of ligands including at least a first species of ligand comprising an ethylene glycol portion and an amine group and at least a second species of ligand comprising a carbohydrate group, for use ...
Device for the transdermal delivery of rotigotine
Amarin Technologies S.a.
November 30, 2017 - N°20170340578

A transdermal delivery system (tds) for the transdermal administration of rotigotine, comprising an adhesive matrix layer, a backing film and release liner, wherein the adhesive matrix comprises rotigotine, an adhesive polymer and a copolymer of polyethylene glycol, polyvinyl caprolactam and polyvinyl acetate. Preferentially, the adhesive polymer is the block styrene-isoprene-styrene (sis).
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Immediate release abuse deterrent liquid fill dosage form
Pharmaceutical Manufacturing Research Services, Inc.
November 30, 2017 - N°20170340574

The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form.
Sublingual fentanyl formulations containing a permeation enhancer
Insys Development Company, Inc.
November 30, 2017 - N°20170340557

Sublingual formulations containing fentanyl, a pharmaceutically acceptable salt or ester thereof, ethanol, propylene glycol and menthol, as well as methods of treating pain by administering the formulations of the invention to a patient in need thereof.
Hair cosmetic composition
Hoyu Co., Ltd.
November 30, 2017 - N°20170340546

A hair cosmetic composition includes an alkaline agent and an oxidant, and is constituted as a hair dye or a hair bleaching/dye removing agent. The hair cosmetic composition further includes (a) a cellulose derivative and (b) a polyethylene glycol having a number average molecular weight of 2,000 or less. The mass ratio of the content of the (b) component to ...
Dye composition comprising a para-phenylenediamine oxidation base, a nonionic surfactant in a medium rich in ...
L'oreal
November 30, 2017 - N°20170340536

The present invention relates to a composition for dyeing keratin fibres, in particular keratin fibres such as the hair, comprising: a) at least one oxidation base 3-(2,5-diaminophenyl)-1-propanol and/or acid salts thereof or solvates thereof such as hydrates; b) at least one coupler; c) at least 10% by weight of the total weight of the composition of a ...
Heat reversible composition for smoking goods that are gel-like at normal temperatures
Japan Tobacco Inc.
November 30, 2017 - N°20170340005

The present invention provides a thermoreversible composition for smoking goods that are gel-like at normal temperatures, comprising glycerin at 69. 0-94. 8 wt % with respect to the entirety of the composition, native-type gellan gum at 0. 2-1. 0 wt % with respect to the entirety of the composition, and water at 5. 0-30. 0 wt %.
Emulsion/colloid mediated flavor encapsulation and delivery with tobacco-derived lipids
Philip Morris Usa Inc.
November 30, 2017 - N°20170340004

Flavorants are emulsified in tobacco-derived lipids and encapsulated with biopolymers and polysaccharides. The emulsions include oil-in-water emulsions, oil-in-water-in-oil emulsions, water-in oil emulsions, or water-in-oil-in-water emulsions, and optionally include ethanol and/or propylene glycol in an oil phase.
Oral rehydration composition and methods thereof
Kalmarna Limited
November 30, 2017 - N°20170339997

An oral rehydration composition comprising the following: 1-glutamic acid in a range of about 0. 01% to about 0. 40% w/w and monosodium glutamate in a range of about 0. 05% to about 0. 80% w/w; about 1. 50% w/w glucose monohydrate; about 0. 20% w/w sodium chloride; about 0. 15% w/w potassium chloride; about 0. 35% w/w glycine; about 0. 30% w/w trisodiumcitrate; about 0. 15% w/w sodium dihydrogen phosphate; about 0. 10% ...
Stevia extract containing selected steviol glycosides as flavor, salty and sweetness profile modifier
Purecircle Usa Inc.
November 30, 2017 - N°20170339994

Stevia extracts with selected major steviol glycosides (reb a, stevioside, reb d, reb c) and minor steviol glycosides and glycosylated diterpene derivative plant molecules, derived from stevia rebaudiana plant are found to improve the perception of flavor and taste perception, which includes the sweet, savory and salty perception in a wide range of food and beverage applications.
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