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This page is updated frequently with new Gly-related patent applications. Subscribe to the Gly RSS feed to automatically get the update: related Gly RSS feeds. RSS updates for this page: Gly RSS RSS


Computer-implemented system and method for facilitating accurate glycemic control by modeling blood glucose using…

Computer-implemented system and method for facilitating accurate glycemic control by modeling blood glucose using…

Medical implant having a conductive coating

Medical implant having a conductive coating

Medical implant having a conductive coating

Method and apparatus for recovering lactide from polylactide or glycolide from polyglycolide

Date/App# patent app List of recent Gly-related patents
10/23/14
20140317777
 Cassava patent thumbnailCassava
Provided are methods for reducing levels of cyanogenic glycosides and improving protein content in plants, as well as plants containing reduced levels of cyanogenic glycosides and improved protein content. In one aspect, such methods comprise, and such plants are created via, tissue-specific expression of a storage protein such as hydroxynitrile lyase in the apoplastic space of cells of the roots and tubers of such plants..
10/23/14
20140316759
 Computer-implemented system and method for facilitating accurate glycemic control by modeling blood glucose using cloud-based circadian profiles patent thumbnailComputer-implemented system and method for facilitating accurate glycemic control by modeling blood glucose using cloud-based circadian profiles
A computer-implemented system and method for facilitating accurate glycemic control by modeling blood glucose using cloud-based circadian profiles is provided. Anti-hyperglycemic medications are categorized based on similar glucose lowering effects.
10/23/14
20140316482
 Medical implant having a conductive coating patent thumbnailMedical implant having a conductive coating
A coated medical implant and associated method are disclosed. The coated medical implant can include a metallic outer surface.
10/23/14
20140316097
 Method and apparatus for recovering lactide from polylactide or glycolide from polyglycolide patent thumbnailMethod and apparatus for recovering lactide from polylactide or glycolide from polyglycolide
The present invention relates to a process for recovering lactide from polylactide (pla) or glycolide from polyglycolide (pga), in which, in a first step, pla or pga is contacted with a hydrolysing medium and hydrolytically degraded to oligomers. In a further step, a cyclising depolymerisation of the oligomers obtained in the first step is effected to give lactide or glycolide.
10/23/14
20140316067
 Method for preparation of polyester/polyolefin hot-melt adhesive for use in a solar cell bus bar patent thumbnailMethod for preparation of polyester/polyolefin hot-melt adhesive for use in a solar cell bus bar
A method of preparing a polyester/polyolefin hot-melt adhesive for use in a solar cell bus bar is disclosed, in which 2,6-naphthalenedicarboxylic acid and ethylene glycol are first sequentially subjected in a predetermined ratio to esterification and polycondensation in the presence of a certain amount of a titanium-based catalyst to result in a polyethylene naphthalate (pnt) with a weight-average molecular weight of 16,000˜20,000. The pnt is then melt-blended with a low-density polyethylene (ldpe) in the presence of a compatibilizer to produce the hot-melt adhesive that can be shaped into films having a high light transmittance, good mechanical properties, high heat and yellowing resistance and thus particularly suitable for use in solar cell bus bars..
10/23/14
20140316055
 Toughening cross-linked thermosets patent thumbnailToughening cross-linked thermosets
Grafted triglycerides comprising an acrylated triglyceride grafted with a fatty acid residue containing 4 to 28 carbon atoms. Also described are methods for making a grafted triglyceride and for curing a material selected from vinyl esters and unsaturated polyesters and mixtures thereof and optionally a reactive diluent.
10/23/14
20140316042
 Waterborne mid-coat paint composition patent thumbnailWaterborne mid-coat paint composition
Composition comprising a polyester resin (a) made waterborne by adding 7-20 mass %, based on resin solids content of (a), of (a) a c1-3 alkoxy group-containing glycol monoalkyl ether to a polyester resin of resin acid value 25-35 mgkoh/g and neutralizing with a secondary amine and/or tertiary amine; a melamine resin (b) comprising methylated melamine resin and methyl/butyl mixed alkylated melamine resin, the content ratio based on resin solids content by mass of the methylated melamine resin to the methyl/butyl mixed alkylated melamine resin from 50/50 to 90/10, and the content ratio based on resin solids content by mass of component (a) to component (b) is 70/30 to 90/10, and a polypropylene glycol (c) comprising a number average molecular weight between 400 and 1,200, and in a mass percentage between 1 and 10 mass % in terms of the combined resin solids contents by mass of component (a) and component (b).. .
10/23/14
20140316038
 Primary pvc plasticizers derived from vegetable oils, process for obtaining primary pvc plasticizers derived from vegetable oils and plasticized pvc composition patent thumbnailPrimary pvc plasticizers derived from vegetable oils, process for obtaining primary pvc plasticizers derived from vegetable oils and plasticized pvc composition
The present descriptive report refers to a patent of invention of pvc plasticizers composed of epoxidized bioesters of vegetable oil fatty acids obtained by partial transesterification with an alcohol, and glycerin and further acetylation and epoxidation, and pvc compounds plasticized with bioesters resulting from partial transesterification, acetylation and epoxidation, belonging to the technical field of polymer additives that were developed to improve the properties of pvc polymers, in addition to providing a lower cost for renewable compounds, such as those obtained with the use of vegetable oils. The epoxidized bioesters of the present invention are composed by mixtures of epoxidized ethyl esters and acetylated and epoxidized mono, di and triglyceril esters, presenting oxirane index between 4 and 8.
10/23/14
20140316010
 Composition for the treatment of dandruff patent thumbnailComposition for the treatment of dandruff
A composition for treating dandruff is provided. The composition includes glycerol with a concentration of not larger than 10 wt %, a second, low molecular weight polyol with a concentration of not larger than 10 wt %, and a saline solution.
10/23/14
20140316004
 Treatment of poultry for reducing  the feed conversion rate or for reducing the incidence of ascites patent thumbnailTreatment of poultry for reducing the feed conversion rate or for reducing the incidence of ascites
Wherein r1 and r2 are independently an alkyl, an alkenyl or a hydroxyalkyl radical containing 1 to 18, preferably 1 to 6 carbon atoms or wherein r1 and r2 form jointly together with the n atom a heterocyclic 5- or 6-membered ring. The glycine compound is preferably n,n-dimethylglycine (dmg).
10/23/14
20140316001
Enriched injectable emulsion containing selected fatty acid triglycerides
A composition including a triglyceride containing glycerol which is esterified with three fatty acids, wherein the three fatty acids include at least one fatty acid selected from caprylic acid, capric acid, α-linolenic acid, linoleic acid, oleic acid, arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid. The total amount of caprylic acid, capric acid, a-linolenic acid, linoleic acid, oleic acid, arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid and docosapentaenoic acid is greater than 60%, based on the total weight of the fatty acids in a base or starting emulsion.
10/23/14
20140315993
Natural sweetener
The invention relates to extracts, in particular non-nutrient phytochemicals, form sugar cane or sugar beet waste products, such as molasses, sugar mud and bagasse, which have glycemic index (gi) lowering properties and their use as sweeteners and in foods containing sugar.. .
10/23/14
20140315970
Ectoparasiticidal formulations
The invention provides an ectoparasiticidal formulation which comprises an ectoparasiticidal agent, preferably fipronil, as the pesticidally-active ingredient, together with a crystallization inhibitor selected from the group consisting of alkyl-substituted pyrrolidones, and optionally, one or more organic solvents and/or co-solvents. Preferably, the crystallization inhibitor is n-octyl pyrrolidone, and the organic solvent, if present, preferably comprises diethylene glycol monoethyl ether.
10/23/14
20140315969
Ectoparasiticidal methods
The invention provides an ectoparasiticidal formulation which comprises an ectoparasiticidal agent, preferably fipronil, as the pesticidally-active ingredient, together with a crystallization inhibitor selected from the group consisting of alkyl-substituted pyrrolidones, and optionally, one or more organic solvents and/or co-solvents. Preferably, the crystallization inhibitor is n-octyl pyrrolidone, and the organic solvent, if present, preferably comprises diethylene glycol monoethyl ether.
10/23/14
20140315928
Substituted amide compounds
The present invention is directed at substituted amide compounds, pharmaceutical compositions containing such compounds and the use of such compounds to reduce plasma lipid levels, such as ldl-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by high levels of ldl-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans.. .
10/23/14
20140315836
Protective agent for keratoconjunctiva or suppressive agent for keratoconjunctival disorder
An object of the present invention is to provide a protective agent for the keratoconjunctiva or a suppressive agent for a keratoconjunctival disorder having an excellent suppressive effect on a keratoconjunctival disorder. The invention relates to a protective agent for the keratoconjunctiva or a suppressive agent for a keratoconjunctival disorder containing glucosylglycerol as an active ingredient, use of glucosylglycerol for the manufacture of a pharmaceutical for protecting a keratoconjunctiva or suppressing a keratoconjunctival disorder and a method of protecting a keratoconjunctiva or suppressing a keratoconjunctival disorder comprising administering glucosylglycerol..
10/23/14
20140315826
Polymeric conjugates of c-1 inhibitors
Polymer conjugates containing a c1-inhibitor having at least one substantially non-antigenic polymer covalently attached to the c1-inhibitor via glycan group of the c1 inhibitor is provided. In addition, methods of making the conjugates as well as methods of treatment using the conjugate of the present invention are also provided..
10/23/14
20140315815
Use of sulfated glycosaminoglycans for improving the bioavailability of factor viii
The present invention relates to pharmaceutical preparations comprising one or more factor viii and a sulfated glycosaminoglycan for increasing the bioavailability of factor viii upon non-intravenous administration. The invention further relates to the combined use of factor viii and a sulfated glycosaminoglycan for the treatment and prevention of bleeding disorders, whereby the bioavailability of factor viii is increased, and to a method for increasing the bioavailability after non-intravenous administration of factor viii by coadminstration of a sulfated glycosaminoglycan..
10/23/14
20140315781
Methods of treating fatty liver disease with helminth-derived glycan-containing compounds
The present invention provides a compound comprising a helminth-derived glycan and/or glycoconjugate thereof (e.g., a compound comprising a lewisx antigen (e.g., lnfpiii), a non-lewisx antigen (e.g., lnnt, ldn, and ldn derivatives), or a mixture of lewisx and non-lewisx antigens (e.g., sea)), useful as a therapeutic compound for treating or preventing diseases associated with fat accumulation in the liver. The compounds of the invention are useful for treating or preventing the development of a fatty liver disease in a subject that has the disease or is at risk of developing the disease, and inhibiting lipogenesis in hepatocytes.
10/23/14
20140315719
Tablets with improved friability
Tablets are prepared with friability reducing agents to yield tablets that are more resistant to breakage or crumbling, but with satisfactory hardness. The friability reducing agents include low molecular weight polyethylene glycol as well as similar agents exhibiting at least three percent (3%) hydroxide moieties and a water solubility of at least eighty percent (80%) (w/w %) in room temperature water.
10/23/14
20140315717
Methods and compositions for improving plant health
The present invention provides methods and compositions for improving plant health. In particular, application of dicamba or another substrate of dmo, or metabolites thereof including dcsa, to a plant confers tolerance to, or defense against, abiotic or biotic stresses such as oxidative stress including herbicide application, and plant disease, and enhances crop yield.
10/23/14
20140315265
Process of producing oil from algae using biological rupturing
A process for production of biofuels from algae can include cultivating an oil-producing algae, extracting the algal oil, and converting the algal oil to form biodiesel. Extracting the algal oil from the oil-producing algae can include biologically rupturing cell wall and oil vesicles of the oil-producing algae using at least one enzyme such as a cellulose or glycoproteinase, a structured enzyme system such as a cellulosome, a virus, or combination of these materials..
10/23/14
20140315246
Composite sugar chain hydrolase
The present invention provides a novel endo-β-n-acetylglucosaminidase (endo-om) using a transformant produced by cloning an endo-β-n-acetylglucosaminidase (endo-om) gene originated from a methylotrophic yeast ogataea minuta ifo10746 strain. The endo-om according to the present invention has a specific activity 13-fold higher than that of known endo-m and a vmax value 55-fold higher than that of the known endo-m, and is useful for the analysis of the structures of sugar chains, including complex type sugar chains, in glycoproteins and the modification of the sugar chains.
10/23/14
20140315212
Alpha toxin detection of gpi anchored proteins
The present invention relates to a method for the purification, concentration and identification of glycosylphosphatidylinositol anchored proteins (gpi-aps) from a biological sample (cells, tissues and/or blood/serum) in a patient or subject, including a human patient or subject. A new method to separate gpi-anchored glycoproteins, a class of glycoproteins found in all animal cells and fluids including serum, from other glycoproteins and proteins for the purpose of identifying potential biomarkers for various diseases, including cancer, especially breast cancer, vaginal cancer, endometrial cancer, uterine cancer, cervical cancer, pancreatic cancer and prostate cancer.
10/23/14
20140315188
Assessment of pml risk and methods based thereon
The invention provides a method of assessing the risk of occurrence of progressive multifocal leukoencephalopathy (pml) in a subject as well as a method of stratifying a subject undergoing α4-integrin and/or vla-4 blocking agent treatment for suspension of the treatment and a method of stratifying a subject undergoing highly active antiretroviral therapy (haart) for alteration of haart. These methods comprise detecting the level of p-selectin glycoprotein ligand-1 (psgl-1) expressing t cells in a sample from the subject..
10/23/14
20140315033
Glycerol diesters, method for producing same, and use of same in coating materials
And the radicals r3, r4, r5, and r6 independently of one another are a saturated, aliphatic radical having 1 to 20 carbon atoms, with the proviso that the radicals r3 and r4 together contain at least 5 carbon atoms and the radicals r5 and r6 together contain at least 5 carbon atoms. Also described is a process for preparing the glycerol diesters, use thereof as reactive diluents, coating materials comprising the glycerol diesters, multicoat paint systems and their production, comprising the use of the coating materials, and also to substrates coated therewith..
10/23/14
20140314911
Deep-sea fish oil capsule and its preparation method
A deep-sea fish oil capsule includes contents and glue. The contents include following parts by weight of raw materials: deep-sea fish oil 160 parts by weights to 200 parts by weights; fish squalene 70 parts by weights to 90 parts by weights; soybean lecithin 10 parts by weights to 15 parts by weights; ginkgo extracts 7 parts by weights to 12 parts by weights; vitamin e 1 part by weights to 3 parts by weights; and beeswax 15 parts by weights to 30 parts by weights.
10/23/14
20140314820
Antimicrobial solution and methods of making and using the same
A chitosan solution is formed from chitin, which is a homopolymer of beta (1-4)-linked n-acetyl-d-glucosamine. Rinsed, dried and ground chitin undergoes a process of deacetylation to convert some n-acetyl glucosamine to glucosamine, a primary component of chitosan.
10/23/14
20140314797
Yeast strain for the production of proteins with terminal alpha-1,3-linked galactose
Lower eukaryotic host cells have been engineered to produce glycoprotein having at least one terminal α-galactosyl epitope. The glycoproteins are useful for the production of highly antigenic glycoprotein compositions with advantages for the production of vaccines..
10/23/14
20140314730
Composition and methods for relief of chemical sensitivity
The formulations of the present disclosure alter the perception of symptoms, especially as experienced by subjects reporting the characteristic features associated with the syndrome known as multiple chemical sensitivity (mcs). The present disclosure encompasses formulations for the relief of symptoms associated with mcs, where the formulations comprise orthophosphoric acid, a vegetable oil comprising an esterified mono-unsaturated fatty acid, folic acid, and a molybdenum salt.
10/23/14
20140314697
Method for inhibiting inflammation and reducing melanophilin expression with glycine derivatives and the composition thereof
This invention discloses method for inhibiting inflammation and reducing melanophilin expression with glycine derivatives and the composition thereof. The mentioned glycine derivatives can not only efficiently inhibit skin inflammation, but also can present significant melanophilin expression reduction.
10/23/14
20140314686
Polyphenol/flavonoid compositions and methods of formulating oral hygienic products
Microemulsions and soluble alkali metal salts of relatively insoluble aglycone polyphenols within oral hygienic products are disclosed for treating oral inflammatory disorders. The formulations can act as a bactericide or bacteriostat.
10/23/14
20140314669
Compounds for binding to the platelet specific glycoprotein iib/iiia and their use for imaging of thrombi
The present invention relates to novel fluorine containing compounds, methods for their preparation, the intermediates of the synthesis, their use as diagnostic agents, especially for imaging of thrombi. The invention relates to positron emission tomography (pet) agents and associated precursor reagents, and methods for producing such radiolaveled agents for imaging of thrombi in a mammalian body.
10/23/14
20140314620
Application of oxygen scavengers to glycol systems
An oxygen scavenger composition is effective in reducing oxygen-induced corrosion in aqueous systems that contain water, oxygen and a significant proportion (at least about 20 wt %) of a glycol, such as monoethylene glycol (meg). The oxygen scavenger composition contains a sulfite, a transition metal salt, and a stabilizer to enhance the kinetics of oxygen removal (scavenging).
10/23/14
20140312332
Printable composition of a liquid or gel suspension of diodes
An exemplary printable composition of a liquid or gel suspension of diodes comprises a plurality of diodes, a first solvent and/or a viscosity modifier. In other exemplary embodiments a second solvent is also included, and the composition has a viscosity substantially between about 100 cps and about 25,000 cps at about 25° c.
10/16/14
20140310129
Method and a system for providing product information to media displaying devices
The present invention concerns a method for providing product information to at least one media displaying device (1) having output means and a data reception unit, the at least one media displaying device being located in at least one store (10), each store (10) comprising at least one data emitting device (2), characterized in that it comprises the steps of: (a) generating, at a central back-office server (3) connected to the store data emitting unit (2), an individual glyph corresponding to each different character or symbol of the product information; (b) generating at least a display script comprising reference and position data of said glyphs in the product information; (c) transmitting the display script and the individual glyphs to the store data emitting device (2); (d) transmitting the display script to the media displaying device (1); (e) broadcasting the individual glyphs; (f) selecting and loading in the media displaying device (1) individual glyphs corresponding to the reference data comprised in the display script; and (g) displaying the selected and loaded individual glyphs at the output means of the media displaying device (1) according to the position data comprised in the display script. The present invention also concerns a central back-office server, an media displaying device and a system thereof..
10/16/14
20140309738
Membrane-scaffold composites for tissue engineering applications
Collagen-glycosaminoglycan membrane shell scaffold core composites for connective tissue engineering that avoids aspects of the typical tradeoff between mechanical properties (i.e. Modulus, failure strength) and bioactivity (i.e., permeability and porosity) for porous tissue engineering scaffolds.
10/16/14
20140309442
Epoxidation process
A method for the oxidation of ethylene to form ethylene oxide is provided that includes passing an aqueous stream through a guard bed and one or more ion exchange treatment beds. The guard bed and the aqueous stream contain from about 0.2 to 20 wt % ethylene glycol.
10/16/14
20140309397
Polyurethane elastomers based on tdi prepolymers enriched in the 2,6-tdi isomer cured with trimethylene glycol di-(para amino benzoate)
Polyurethane/urea elastomer compositions which retain their dimensions at elevated temperatures. These polyurethane/urea elastomers surprisingly have improved green strength or dimensional stability upon demolding at typical mold temperatures of 80 to 130 c and remain dimensionally stable throughout the post cure process which is typically overnight at about 100 c.
10/16/14
20140309342
Modeling paste composition and preparation method thereof
The present invention discloses a modeling paste composition which comprises 120-150 parts by weight of a first solvent; 50-100 parts by weight of a second solvent; 18-25 parts by weight of polyvinyl alcohol; 2-3 parts by weight of thickening agent; 1.5-3 parts by weight of preservative agent 10-15 parts by weight of glycerol; 5-10 parts by weight of borax; and 10-15 parts by weight of polystyrene beam. This invention also discloses a preparing method and use thereof.
10/16/14
20140309328
Polymer for contact lenses
The present invention relates to polyurethane polymer compositions prepared by reacting a mixture comprising: a) at least one poly(ethylene glycol), b) at least one polyoxyalkylene diol (typically ppg or a copolymer of ethylene oxide and propylene oxide), c) at least one di- or poly-isocyanate, d) at least one polyol or macropolyol having a functionality greater than 2, or a mixture of such polyols or macropolyols having a functionality greater than 2, e) optionally an additional compound comprising at least one hydroxyl group and at least one primary or secondary amine group. The present invention also relates to an article comprising such a polymer, in particular a medical device such as a contact lens.
10/16/14
20140309322
Processes for obtaining a polyol from palm oil, polyols obtained from said processes, products derived from said polyol and method for preparing same
The present invention relates to the process for production of a polyol from palm oil and of rigid polyurethane foams prepared from said polyol derived from palm oil. On the one hand, this invention provides a method for obtaining monomeric polyols from palm oil that have hydroxyl number between 50 450 mgkoh/g sample.
10/16/14
20140309315
Carboxymethylcellulose polyethylene glycol compositions for medical uses
Compositions comprising carboxypolysaccharides (cps) including carboxymethyl cellulose (cmc) and polyethylene glycols (pegs) are provided where the peg is a peg-epoxide covalently linked to the cps. In certain embodiments, the peg attaches to only one cps, forming a decorated cps.
10/16/14
20140309299
Stabilized pharmaceutical preparations in containers having limited perviousness to water vapor
The present invention relates to a pharmaceutical preparation, comprising a mixture of at least one pharmaceutical active ingredient, at least one alcohol component and at least one triglyceride component, in a plastic container, characterized in that the plastic has a water vapour permeability of no more than 3.0 g/m2/24 h (measured on a film 100 μm thick at 40° c. And 90% relative humidity..
10/16/14
20140309295
Antiepileptic, hypocholesterolemic and neuroprotective compound
Its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. For its use in the prevention of: neurodegenerative diseases, cognitive deterioration, diseases associated with undesired oxidation, age-associated pathological processes and progeria, epilepsy, epileptic seizures and convulsions, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, or fungal or viral infections..
10/16/14
20140309168
Modified peptides and proteins
Provided are compounds and methods of making compounds containing two or three groups derived from a peptide, such as enfuvirtide or exenatide, covalently bound to a linker. The compounds may contain polyethylene glycol groups to enhance solubility and pharmacokinetic properties.
10/16/14
20140309161
Modified antibiotic peptides having variable systemic release
The invention relates to modified antibiotic peptides, in particular derivatives of apidaecin and oncocin, preferably having increased stability, reduced immunoreaction, and improved pharmacokinetics. In the invention, the peptide antibiotics are reversibly protected by means of a linker having the polymer polyethylene glycol (peg).
10/16/14
20140309135
Remedy for diabetes
A method of screening a compound having a hypoglycemic effect (hereinafter referred to as “hypoglycemic compound”), a remedy for diabetes which contains a compound having a novel function mechanism, etc. More specifically speaking, a method of screening a hypoglycemic compound capable of binding to the β subunit of a trimeric gtp-binding protein, a remedy for diabetes comprising a hypoglycemic compound, which is characterized by being capable of binding to the β subunit of a trimeric gtp-binding protein, as the active ingredient, etc..
10/16/14
20140308726
Controlling bacterial biofilms in ethanol production
A high yield method for fermenting carbohydrate to ethanol and prevention and/or disruption of biofilms, comprising: a) mixing a fermentation feedstock with a fermentation broth containing yeast and/or an enzyme, b) treating said mixture by adding a composition to the fermentor containing: 10-90 wt. % of an aldehyde selected from the group consisting of formaldehyde, para-formaldehyde, glutaraldehyde, another antimicrobial aldehyde, and mixtures thereof, 1-50 wt.
10/16/14
20140308724
Yeast expressing saccharolytic enzymes for consolidated bioprocessing using starch and cellulose
The present invention is directed to a yeast strain, or strains, secreting a full suite, or any subset of that full suite, of enzymes to hydrolyze corn starch, corn fiber, lignocellulose, (including enzymes that hydrolyze linkages in cellulose, hemicellulose, and between lignin and carbohydrates) and to utilize pentose sugars (xylose and arabinose). The invention is also directed to the set of proteins that are well expressed in yeast for each category of enzymatic activity.
10/16/14
20140308710
Peg-mediated assembly of nucleic acid molecules
The present invention discloses methods for assembling a nucleic acid molecule from a set of overlapping oligonucleotides. The method involves contacting a set of overlapping oligonucleotides with a dna polymerase, a mixture of dntps, and a crowding agent to form an assembly mixture.
10/16/14
20140308702
Yeast recombinant cell capable of producing gdp-fucose
A yeast strain expressing a bi-functional fucokinase/gdp-l-fucose pyrophosphorylase enzyme and capable of producing gdp-l-fucose in vivo is provided. Also provided are yeast cells which express a gdp-l-fucose transporter and/or a fucosyl transferase with the bi-functional enzyme.
10/16/14
20140308699
Yeast artificial chromosome carrying the mammalian glycosylation pathway
A yeast artificial chromosome (yac) directing the expression of one or more activities of the humanized glycosylation pathway is provided. The said yac comprises one or more expression cassettes for fusion proteins of heterologous glycosylation pathway and an er/golgi retention sequence.
10/16/14
20140308684
Quantification of non-reducing end glycan residual compounds
Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.. .
10/16/14
20140308422
Liquid composite high-intensity sweetener and preparation method thereof
A liquid composite high-intensity sweetener, comprises a sweet substance and a solvent, wherein the sweet substance is one or combination of a plurality of the following components: aspartame, sucralose, acesulfame and neotame; and the solvent comprises water and one or combination of a plurality of the following components: ethanol, propylene glycol, phosphoric acid, citric acid, lactic acid, acetic acid, malic acid, ascorbic acid, glucose acid, tartaric acid, acetate, lactate, citrate, phosphate, sorbic acid, sorbate, benzoic acid and benzoate. In addition, the present invention further claims a method for preparing the liquid composite high-intensity sweetener.
10/16/14
20140308392
Meal intended for human consumption
This invention relates to a plurality of compositions for dietary health management and its use in the prevention or treatment of cardiovascular disease or type 2 diabetes, and also in the prevention and/or management of obesity and generally in weight management and loss. Thus a meal intended for human consumption is provided, the meal comprising: (a) 250-650 kilocalories (1045-4180 kilojoules); (b) 10-50, preferably 20-50, more preferably 30-50 g fibre; (c) 10-50, preferably 10-30, more preferably 10-20 g protein; (d) 0 to 5, preferably less than 3 g starch; and (e) 0 to 2, preferably 0 to 1, most preferably 0 to 0.5 g lactose; (f) at least 20, preferably at least 30, most preferably at least 40 mg of any one flavonoid aglycone; and (g) at least 30, preferably at least 40, most preferably at least 50 mg of any one flavonoid glucoside; wherein the meal comprises 75-1000 mg of total flavonoid aglycone and flavonoid glucoside, wherein the meal comprises no more than 250 mg of any one flavonoid aglycone, wherein the meal comprises no more than 250 mg of any one flavonoid glucoside..
10/16/14
20140308375
Antimicrobial & antiviral composition
A method of reducing the number of microorganisms entering the nose and proliferating in the nasal cavity including application of a solution of an antimicrobial, antiviral and antifungal composition to the anterior vestibular region of the nares. The antimicrobial, antiviral and antifungal solution includes ethyl alcohol as an active ingredient.
10/16/14
20140308368
Ophthalmological aqueous composition
The present invention provides an aqueous ophthalmic composition containing (a) a terpenoid, (b) zinc chloride, and (c) at least one member selected from the group consisting of cellulose-based polymeric compounds, vinyl-based polymeric compounds, polyethylene glycols and dextran. According to the present invention, an aqueous ophthalmic composition is provided in which adsorption of the terpenoid to a container can be inhibited, thereby making it possible to inhibit the reduction in the terpenoid content for a long period of time, the aqueous ophthalmic composition having some excellent actions such as an inhibitory action for histamine release, and an inhibitory action for discharges from the eyes..
10/16/14
20140308365
Pharmaceutical composition useful for adhesion prevention or hemostasis
An object of the present invention is to provide a pharmaceutical composition that has excellent water solubility, contains a gelling agent that has a gelation rate in suitable ranges, and is useful as an adhesion preventing biomedical material. Another object of the present invention is to provide a pharmaceutical composition that can demonstrate an excellent hemostatic effect.
10/16/14
20140308357
Melatonin-based solutions and powders for their preparation
The present invention relates to a powder for reconstitution before use for preparations for injection containing melatonin, at least one soluble excipient and at least one surfactant for the treatment of neonatal cerebral infarction. The present invention also relates to a preparation for injection in the form of a solution obtained by dissolving a powder to be reconstituted comprising melatonin, at least one soluble excipient and at least one surfactant, in a mixture of water and polyalkylene glycol, in which the melatonin is present in quantities of from 3 to 30 mg/ml and the polyalkylene glycol is present in quantities from 5 to 40% of the total volume of the liquid used..
10/16/14
20140308341
Methods and compositions for liposomal formulation of antigens and uses thereof
The present invention relates to liposomal vaccine compositions, methods for the manufacture thereof, and methods for the use thereof to stimulate an immune response in an animal. These compositions comprise dimyristoylphosphatidylcholine (“dmpc”); either dimyristoylphosphatidylglycerol (“dmpg”) or dimyristoyltrimethylammonium propane (“dmtap”) or both dmpc and dmtap; and at least one sterol derivative providing a covalent anchor for one or more immunogenic polypeptide(s) or carbohydrate(s)..
10/16/14
20140308308
Compositions and methods for treatment of cytomegalovirus
The present disclosure provides compositions and methods useful for treating hcmv infection. As described herein, the compositions and methods are based on development of immunogenic compositions that include virus-like particles (vlps) which comprise one or more moloney murine leukemia virus (mmlv) core proteins and include one or more hcmv epitopes, such as, for example, from hcmv envelope glycoproteins gb and/or gh and/or tegument protein pp65.
10/16/14
20140308266
Modified neurotoxins with poly-glycine and uses thereof
The present invention is concerned with modified neurotoxins. Specifically, it relates to a modified biologically active neurotoxin polypeptide comprising at least one poly-glycine domain.
10/16/14
20140308228
Use of glycosaminoglycan lipoate esters in the trichology field
Disclosed is the use of glycosaminoglycan esters, whose alcohol groups are partly esterified with lipoic acid or with lipoic acid and formic acid, in hair are treatments.. .
10/16/14
20140308214
Pharmaceutical composition
The present invention relates to pharmaceutical compositions for inhalation comprising glycopyrrolate, a beta2-agonist, and optionally an inhaled corticosteroid; to a process for preparing such compositions and to the use of such compositions for the prevention and/or treatment of respiratory, inflammatory or obstructive airway disease.. .
10/16/14
20140308209
Soluble mediator
The present disclosure relates to a soluble cd52 glycoprotein and its use in treating diseases regulated by effector t-cells, for example autoimmune diseases such as type 1 diabetes. The present disclosure also relates to fusion proteins comprising the soluble glycoprotein, to cells expressing high levels of cd52, and to diagnostic methods based on the detection of cd52 expression levels in a subject..


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Gly topics: Door Assembly, Swimming Goggles, Transverse, Alkoxylate, Fluoropolymer, Air Cleaning, Rotor Shaft, Aspect Ratio, Disconnect, Synchronization, Remote Control, Ethylene Glycol, Surfactant, Combustion, Steviol Glycosides

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