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Petroleo Brasileiro S.a. - Petrobras
Hydroesterification process for producing biodiesel from wet microalgae biomass
|| List of recent Gly-related patents
| Oleic and medium chain length triglyceride based, low viscosity, high flash point dielectric fluids|
A dielectric fluid comprising in weight percent based on the weight of the composition: a. 30 to 70% c18:1 fatty acids; b.
Dow Global Technologies Llc
| Non-oleic triglyceride based, low viscosity, high flash point dielectric fluids|
A vegetable-based dielectric fluid comprising in weight percent of triglycerides based on the weight of the fluid: a. Greater than 0 to 100% of at least one of c14:1 or c16:1 fatty acids; and at least one of: b.
Dow Global Technologies Llc
| Isobaric aldehyde-reactive tags for and analysis of glycans using same|
Highly specific and novel methods for analyzing glycans and proteoglycans are provided. Uses of the information generated by the inventive methods for diagnosis and treatment are also disclosed..
The Johns Hopkins University
| Method for isolating valuable metal|
Provided is a method that selectively extracts and, at a low cost, recovers indium from an acidic solution containing indium and gallium. The present invention is a method that is for isolating a valuable metal and that, by means of subjecting an acidic solution containing indium and gallium to a solvent extraction that is by means of an extraction agent comprising an amide derivative represented by a general formula, extracts indium from the acidic solution.
Sumitomo Metal Mining Co., Ltd.
| Methods of cell culture|
Polypeptide preparations having target levels of glycans, and methods of producing such polypeptide preparations using dmso, are described.. .
Momenta Pharmaceuticals, Inc.
| 3-hydroxypropionic acid-producing recombinant microorganism and producing 3-hydroxypropionic acid using the same|
Disclosed is a method of producing 3-hydroxypropionic acid comprising the step of culturing recombinant microorganism comprising a nucleic acid sequence encoding ilyobacter polytropus-derived glycerol dehydratase, and a nucleic acid sequence encoding dehydrogenase, which converts 3-hydroxypropionaldehyde into 3-hydroxypropionic acid, and a recombinant microorganism used therefor. According to the present invention, the production of 3-hydroxypropionic acid remarkably increases and the production amount of 1,3-propanediol (1,3-pdo), which is generated as by-products when producing 3-hydroxypropionic acid, remarkably decreases, compared to known recombinant microorganisms comprising gene expressing klebsiella pneumonia-derived vitamin b12-dependent glycerol dehydratase..
Samsung Electronics Co., Ltd.
| Hydroesterification process for producing biodiesel from wet microalgae biomass|
The invention relates to the preparation of carboxylic acid esters compounds, biodiesel (b) from microalgae, for use as a biofuel for compression type ignition. The objective is achieved through a hydroesterification process of a microalgae biomass (mu) comprising a hydrolysis stage and the esterification stage by means of heterogeneous catalysis.
Petroleo Brasileiro S.a. - Petrobras
| Kneading-type antistatic agent, thermoplastic resin composition containing agent, and molded article|
Therefore, the antistatic agent is a kneading-type antistatic agent which is a thermoplastic polymer obtained by irradiating active energy rays toward a solution which contains a ingredient: a polymerizable monomer containing in one molecule one polyalkylene glycol and one polymerizable functional group selected from an acryloyl group and a methacryloyl group, b ingredient: perchlorate and c ingredient: photo polymerization initiator.. .
The present invention relates to polyester that can be obtained by polymerization of a) terephtalacid dimethylester, and b) ethylene glycol, and c) 1,2-propylene glycol, and d) one or a plurality of polyethylene glycols having weight average molecular weights in the range of 1,000 to 2,000 g/mol, and e) one methyl polyethylene glycol having a weight average molecular weight in the range of 1,050 to 1,350 g/mol, f) either when a plurality of compounds having a reticulating effect and 3 to 6 functions that are enabled for polycondensation are present or absent. The polyester according to the invention can be used in an advantageous manner, e.g.
Clariant Finance (bvi) Limited
| Cellulose ether containing cationic group|
 a cationic group-containing cellulose ether, which has a main chain derived from an anhydroglucose, and in which the degree of substitution with a cationized oxyalkylene group per the anhydroglucose unit is from 0.01 to 1.0, the degree of substitution with a glycerol group is from 0.5 to 5.0, and the degree of substitution with a group that contains a hydrocarbon group, has from 3 to 7 carbon atoms and has a specific structure is from 0.0001 to 0.2;  a surfactant composition containing the cationic group-containing cellulose ether, a surfactant and water;  a hair wash composition and a skin cleanser composition containing the cationic group-containing cellulose ether, a surfactant and water;  a hair conditioner composition containing the cationic group-containing cellulose ether, a surfactant, an oily agent and water;  a hair treatment composition containing the cationic group-containing cellulose ether, and at least one treatment agent selected from a hair-coloring dye, an oxidizing agent, an alkali agent and a keratin-reducing agent.. .
Method for extracting and stabilising phycocyanin and the uses thereof
Disclosed is a method for extracting and stabilizing phycocyanin from at least one material containing same. The method includes a step of macerating the material or materials in glycerol or a water/glycerol mixture..
Method for producing glycidol by successive catalytic reactions
Disclosed is a method for producing glycidol by successive catalytic reactions. The method includes a series of reactions for the preparation of glycerol carbonate from glycerol and the decarboxylation of the glycerol carbonate.
Korea Institute Of Science And Technology
Process for hydrogenation of olefinic or acetylenic bonds
The present invention relates to a process for hydrogenation of olefinic or acetylenic bonds. Further, the present invention relates to a process for selective hydrogenation of olefinic or acetylenic bonds and/including triglycerides using modified metal supported on solid acidic metal oxide catalyst and the process for the preparation thereof.
Council Of Scientific And Industrial Research
Method for preparing acrolein from glycerol
The disclosure concerns a method for preparing acrolein from glycerol, according to which a dehydration of the glycerol is carried out in the presence of a catalyst mwoa, wherein mwo represents a mixture of simple oxides and/or mixed oxides of tungsten and at least one metal m selected among zirconium, silicon, titanium, aluminium and yttrium, and a represents one or several lewis base(s), one said lewis base being of the formula b(r1)p(r2)q(r3)r, wherein b is an element selected among c, s, p, o, n and halides, r1, r2 and r3 represent, independently of each other, h, a c1-c6 alkyl group, o, oh or or wherein r represents a c1-c6 alkyl group, and the sum of p, q and r varies from 0 to 4.. .
Universite Claude Bernard
Process for producing high-yield biodiesel applying high acidity triglycerides with generation of glycerin 90% free of salts
A process is provided for producing high-yield biodiesel applying high acidity triglycerides with generation of glycerin 90% free of salts starting from fatty lower cost fatty material allied with an esterification and innovative extraction process that generates a further value, more specifically for the production of biodiesel.. .
Glycerosolution QuÍmica Ltda.
Method for synthesizing silver nanoparticles on tio2 using hybrid polymers
Hybrid tio2 nanostructures with engineered morphologies (flakes, spheres and buds) supporting ag nanocrystals were synthesized based on cooperative sol-gel chemistry of either titanium iso-propoxide or n-butoxide and assembled with polyvinyl alcohol and polyethylene glycol.. .
Umm Al-qura University
Sustained nitric oxide release coating using diazeniumdiolate-doped polymer matrix with ester capped poly(lactic-co-glycolic acid) additive
A polymeric composition includes a polymer matrix having a lipophilic discrete nitric oxide adduct and/or a polymeric nitric oxide adduct associated therewith, by covalent attachment to the polymer matrix and/or by dispersion within the polymer matrix, with the discrete nitric oxide adduct and/or the polymeric nitric oxide adduct being capable of releasing nitric oxide (no). The polymeric composition further includes an ester capped poly(lactide-co-glycolide) (plga) additive to at least one of increase, prolong, and control no release rates from the lipophilic discrete nitric oxide adduct and/or the polymeric nitric oxide adduct..
The Regents Of The University Of Michigan
Indirect chromoendoscopy with an oral indigo carmine base preparation
Indirect chromoendoscopy is performed by providing a subject with an orally administered composition which includes indigo carmine dye mixed with polyethylene glycol (peg). Preferably, the subject ingests at least 160 mg of indigo carmine prior to the endoscopic procedure.
Constructs for enhancing immune responses
Chimeric protein constructs including a herpesvirus glycoprotein d (gd) and a heterologous polypeptide that interact with herpes virus entry mediator (hvem) and enhance and enhance an immune response against the heterologous polypeptide and methods for their use are provided.. .
The Wistar Institute Of Anatomy And Biology
Exendins to lower cholesterol and triglycerides
Provided herein are pharmaceutical formulations containing exendins, exendin agonists, or exendin analog agonists that are administered at therapeutic plasma concentration levels over a sustained period of time to lower total cholesterol levels; to lower ldl-cholesterol levels; to lower triglyceride levels; to treat dyslipidemia; to treat and slow the progression of atherosclerosis; and to treat, prevent, and reduce the risk of heart attacks and strokes in patients. In the pharmaceutical formulations and methods of the invention, the exendin may be exendin-4, an exendin-4 agonist, or an exendin-4 analog agonist.
Astrazeneca Pharmaceuticals Lp
The present invention relates to cyclosporine emulsions containing: (i) a cyclosporine, (ii) a natural oil (long chain triglyceride), (iii) a phosphatidylcholine, (iv) glycerol, (v) a pharmaceutically tolerable alkali salt of a free fatty acid, (vi) a medium chain triglyceride-oil, (vii) optionally, hydrochloric acid or sodium hydroxide for ph adjustment and (viii) water, and to therapeutic methods using them.. .
Neurovive Pharmaceutical Ab
Formulations involving solvent/detergent-treated plasma (s/d plasma) and uses thereof
The invention concerns pharmaceutical formulations comprising solvent/detergent (s/d)-treated plasma and a glycosaminoglycan such as hyaluronic acid, and their use for treating diseases, particularly musculoskeletal diseases.. .
Enrico Bastianelli S.p.r.l.
Chlorhexidine gluconate solubilized in a hydrophobic monoacylglyceride
Chlorhexidine gluconate solubilized in a hydrophobic monoacylglyceride is described. Compositions incorporating such materials, as well as methods of preparing such materials are also described..
3m Innovative Properties Company
Granular material for orally fast disintegrating tablets
The use of a granular material which is for orally fast disintegrating tablets and comprises at least one kind of water soluble polymer and tannic acid allows production of tablets that can be produced by a simple process with simple production equipment, disintegrate fast in the mouth, and have a proper level of moldability for practical use. The at least one kind of water soluble polymer is preferably selected from, the group consisting of povidone, hydroxypropyl cellulose, pallulan, a polyvinyl alcohol-polyethylene glycol graft copolymer and copolyvidone..
Teika Pharmaceutical Co., Ltd.
A method of reducing the likelihood of infection requiring use of antibiotics during or after induction of labour in a female, comprises administering intravaginally to the female an insert comprising a cross-linked polyurethane reaction product of a polyethylene glycol, a triol and a diisocyanate, the insert containing 200 μg misoprostol; the likelihood of infection being reduced in comparison to the administration of said insert containing 10 mg dinoprostone.. .
Ultrasound anti stretch mark gel composition
An improved ultrasound imaging gel for topical use and a method for create such comprising: water, propylene glycol, glycerin, phenoxyethanol or carbopol® 940 polymer, perfumes and dyes combined with equisetum arvense, alchemilla vulgaris, and hedera helix. The improved ultrasound imaging gel may be dispensed from a bottle, where the bottle includes: a body portion, where the body portion includes a slight indenture at a top diameter; a nipple, where the nipple includes an opening for the dispensing of the gel through the opening; and a ribbed base surrounding the nipple..
Hemostatic bioabsorbable device with polyethylene glycol binder
A hemostatic pad comprising a bioabsorbable scaffolding material; a lyophilized thrombin powder, a lyophilized fibrinogen powder, and a meltable binder powder, with all powders disposed on the bioabsorbable scaffolding material. A meltable binder such as peg bonds the lyophilized thrombin powder and the lyophilized fibrinogen powder to the bioabsorbable scaffolding material for improved friability, wettability and performance in a use, such as for hemostatic treatment or sealing at a wound site..
Compositions and methods for the solubilization of stevia glycosides
Various embodiments of the present technology provide a sweetener composition comprising stevia glycosides that may be stably soluble in an aqueous solution, and methods for their manufacture. In various embodiments, the sweetener composition may comprise at least one stevia glycoside and a natural emulsifier.
James And Carol May Family, Lllp
Sweetener compositions comprising particular glycoside blends are described in this paper. The glycoside blends comprise any or all of rebaudioside a, rebaudioside b, and rebaudioside d together with stevioside in various proportions.
Printed circuit board and manufacturing method thereof
There are provided a printed circuit board and a manufacturing method thereof. The printed circuit board (pcb) includes an adhesive film disposed between an insulating layer and a circuit pattern, wherein the adhesive film includes poly(glycidyl methacrylate).
Korea Advanced Institute Of Science And Technology
Intermediate transfer members and processes
An intermediate transfer member that contains a mixture of a polyimide generated from a polyamic acid, an optional conductive component, and a polyethylene glycol silicone phosphate, and processes of preparation thereof.. .
Solid phase glycan and glycopeptide analysis and microfluidic chip for glycomic extraction, analysis and methods for using same
Highly specific and novel solid phase methods for analyzing glycans and proteoglycans using a solid phase system are provided. The present invention also provides an integrated apparatus and methods of use which comprises a high-throughput glycan isolation and reverse-phase liquid chromatography (rplc) for on-chip glycan extraction, modification and separation.
The Johns Hopkins University
Microbial electrochemical cells and methods for producing electricity and bioproducts therein
Bioelectrochemical systems comprising a microbial fuel cell (mfc) or a microbial electrolysis cell (mec) are provided. Either type of system is capable of fermenting insoluble or soluble biomass, with the mfc capable of using a consolidated bioprocessing (cbp) organism to also hydrolyze an insoluble biomass, and an electricigen to produce electricity.
Board Of Trustees Of Michigan State University
Methods for the improvement of product yield and production in a microorgamism through the addition of alternate electron acceptors
The present invention provides for novel metabolic pathways to reduce or eliminate glycerol production and increase product formation. More specifically, the invention provides for a recombinant microorganism comprising a deletion of one or more native enzymes that function to produce glycerol and/or regulate glycerol synthesis and one or more native and/or heterologous enzymes that function in one or more engineered metabolic pathways to convert a carbohydrate source, such as lignocellulose, to a product, such as ethanol, wherein the one or more native and/or heterologous enzymes is activated, upregulated, or downregulated.
Lallemand Hungary Liquidity Management Llc
Glycosylated protein expression in prokaryotes
The present invention relates to a prokaryotic host cell comprising eukaryotic glycosyltransferase activity, where the eukaryotic glycosyltransferase activity is eukaryotic dolichyl-linked udp-glcnac transferase activity and eukaryotic mannosyltransferase activity. Also disclosed is a method of producing a glycosylated protein by providing a prokaryotic host cell comprising the eukaryotic glycosyltransferase activity and culturing the prokaryotic host cell under conditions effective to produce a glycosylated protein.
Cornell Research Foundation, Inc.
Methods for use in modulating mir-122a
Methods are provided for the treatment of cardiovascular or metabolic diseases characterized by elevated serum total cholesterol, elevated serum ldl-cholesterol, or elevated serum triglycerides, through the administration of an oligomeric compound which modulates the levels or activity of mir-122a. Further provided are methods for reducing hepatic steatosis or liver tissue triglyceride accumulation through the administration of an oligomeric compound which modulates the levels or activity of mir-122a.
Regulus Therapeutics Inc.
Strains and methods for plasmid maintenance
The present invention provides a host microorganism with a deletion, disruption or mutation in one or more enzymes of a glycerol dissimilation pathway and a plasmid without an antibiotic resistance gene but carrying one or more genes encoding enzymes involved in glycerol dissimilation, wherein the plasmid is stably maintained by the host microorganism when cultured on glycerol as a carbon source. Such a plasmid maintenance system is beneficial in applications where the presence of an antibiotic resistance gene or the use of antibiotics is either prohibited or problem..
Glycos Biotechnologies, Inc.
(a) a glycerol monoester; (b) an acid amide in which the chain length of the acid portion comprising the amide contains about 8 to about 28 carbon atoms; and (c) a molybdenum compound in which the oxidation state of the molybdenum is +6; and a product prepared by reacting the reactive composition, including a product in the form of a composition which is useful as a friction modifier; and a lubricating composition comprising a lubricant in admixture with the friction modifier.. .
Grease composition for electric power steering device, and electric power steering device
Provided are both a grease composition for an electric power steering device and an electric power steering device. The grease composition can keep a sufficiently low coefficient of friction in a sliding area between a steel and a resin over a long period, is less susceptible to being removed from the sliding area, does not cause break down of an oil film, and thus can minimize the occurrence of stick-slips.
Hitachi Automotive Systems Steering, Ltd.
This document relates to functionalized (e.g., mono- or bi-functional) polymers (e.g., polyethylene glycol and related polymers) as well as methods and materials for making and using such functionalized polymers.. .
Analysis of ubiquitnated polypeptides
The disclosure relates to antibody reagents that specifically bind to peptides carrying a ubiquitin remnant from a digested or chemically treated biological sample. The reagents allow the technician to identify ubiquitinated polypeptides as well as the sites of ubiquitination on them.
Cell Signaling Technology, Inc.
Glucagon-like peptide-1 analogue monomer and dimer, preparation method therefor and application thereof
Provided are a glucagon-like peptide-1 (glp-1) analogue monomer and dimmer, a preparation method thereof, and an application thereof. The glp-1 analogue monomer comprises one cysteine; and the dimer is formed by two monomer molecules connected via an intermolecular disulfide bond formed by the cysteine.
Tianjin Institute Of Pharmaceutical Research
Dipeptidyl peptidase-iv inhibitor
An excellent peptidyl peptidase-iv inhibitor and the like are provided. A peptide consisting of val-pro-x wherein x represents an amino acid residue (except for l-proline residue); the aforementioned x is preferably one selected from a basic amino acid residue, an aliphatic neutral amino acid residue, an amide group-carrying neutral amino acid residue, or an aromatic group-carrying neutral amino acid residue; the aforementioned x is preferably one selected from an alanine residue, a glutamine residue, a methionine residue, an asparagine residue, a glycine residue, a valine residue, a tyrosine residue, a serine residue, and a lysine residue; a dipeptidyl peptidase-iv inhibitor, a blood sugar rise suppressing agent, a vascular endothelial disorder suppressing agent, and an angiotensin converting enzyme inhibitor containing the aforementioned peptide as an active ingredient..
Morinaga Milk Industry Co., Ltd
Tricyclic compounds having antimitotic and/or antitumor activity and methods of use thereof
The present invention provides tricyclic compounds, pharmaceutically acceptable salts, solvates, or hydrates thereof, having antimitotic activity, anti-multidrug resistance activity, for example p-glycoprotein inhibition, and antitumor activity, and which inhibit paclitaxel sensitive and resistant tumor cells. Also provided are methods of utilizing these compounds for treating tumor cells and inhibiting mitosis of cancerous cells..
Duquesne University Of The Holy Spirit
A novel coumarin derivative or a pharmaceutically acceptable salt thereof and also to provide a pharmaceutical agent containing such a compound as an active ingredient is provided. The coumarin derivative or a pharmaceutically acceptable salt thereof exhibits an excellent suppressive action to the destruction of cartilage and suppressive action to the proliferation of synovial cells in a pharmacological test where the release of sulfated glycosaminoglycans (sgag) and the proliferation of synovial cells are used as indicators whereby it is very useful as an active ingredient of a pharmaceutical composition such as a preventive or therapeutic agent for arthropathy such as osteoarthritis or chronic rheumatoid arthritis..
Nippon Zoki Pharmaceutical Co., Ltd.
Crystal structure of bifunctional transglycosylase pbp1b from e. coli and inhibitors thereof
Crystal structure at 2.16 Å resolution of full-length escherichia coli penicillin-binding protein 1b (pbp1b) in complex with its inhibitor moenomycin, is provided. 3d structures of amino acid residues involved in moenomycin binding and transglycosylation activity are identified.
Flux composition and techniques for use thereof
The present invention is directed to flux compositions and uses thereof. One composition comprises an activator and a solvent being a glycerol ethoxylate with a molecular weight of 200-500.
International Business Machines Corporation
Balloon surface coating for valvuloplasty
The present invention is directed to valvuloplasty catheter balloons and balloon catheters for valvuloplasty with such catheter balloons coated with at least one layer containing at least one antiproliferative, immunosuppressive, anti-angiogenic, anti-inflammatory, anti-restenotic and/or anti-thrombotic agent and a top coat consisting of a polyvinyl alcohol-polyethylene glycol graft copolymer as well as the use of these balloon catheters for the prevention of restenosis after valvuloplasty.. .
Artificial bone nanocomposite and manufacture
A composition suitable for bone replacement is provided. The composition is a nanocomposite matrix, resembling both the structure and the properties of natural bone, including morphology, composition and mechanical characteristics.
Matrix-incorporated fluorescent porous and non-porous silica particles for medical imaging
A silica particle for medical imaging includes a bridged silane fluorescent dye incorporated throughout the particle matrix. Copolymerization of a bridged silane fluorescent dye (e.g., (r′o)3si—r—si(or′)3, where r is a fluorescent organic bridging group, and where r′ is a methyl or ethyl group) and a tetralkoxysilane (e.g., si(or′)4, where r′ is a methyl or ethyl group) generates particles of a predetermined size and shape.
International Business Machines Corporation
Cisplatin complex and preparation method thereof
A cddp complex is formed by complexation of cddp and a polymer having a structure of formula (i). The cddp complex has good biocompatibility and is degradable.
Changchun Institute Of Applied Chemistry Chinese Academy Of Science
Compositions and methods for topical delivery of prostaglandins to subcutaneous fat
Described herein are compositions comprising a prostaglandin fp receptor agonist (pfpra) compound and a fatty acid ester (e.g., isopropyl myristate), optionally comprising an ointment base such as a hydrocarbon base (e.g., petroleum jelly) and/or an organic alcohol (e.g., propylene glycol), that, when topically applied to the skin, locally delivers a therapeutically effective amount of the pfpra compound to subcutaneous fat under the skin, and methods of preparation. The therapeutic effect is, for example, reduction of the subcutaneous fat under the skin.
Topokine Therapeutics, Inc.
Compositions comprising siraitia grosvenori extracts and methods for the treatment of infection
A method for the treatment and/or prophylaxis of a viral infection in a subject is provided wherein the method comprises the steps of providing a therapeutically effective amount of a composition comprising an extract of the fruit of siraitia grosvenori swingle and administering the composition to the subject. The fruit from which the extract is derived is luo han guo.
Cascade Estates Limited
Anticholinergic neuroprotective composition and methods
The present invention relates to a pharmaceutical composition comprising propiverine, trospium or glycopyrrolate; and a non-anticholinergic antiemetic agent. It is also related to a pharmaceutical composition comprising a high dose of solifenacin or a pharmaceutically acceptable salts thereof; and a non-anticholinergic antiemetic agent.
Chase Pharmaceuticals Corporation
Organoarsenic compounds and methods for the treatment of cancer
A method for treating a lymphoma selected from non-hodgkin's and hodgkin's lymphoma comprising administering an organoarsenic compound having a structure of the formula (i) wherein x is s or se and r1 and r2 are independently c1-30alkyl (r3, r3′, r4, r5, w and “n” are as defined in claim 1) in particular where the compound is s-dimethylarsinoglutathione, n-(2-s-dimethylarsinothiopropionyl)glycine, 2-amino-3-(dimethylarsino)thio-3-methylbutanoic acid, s-dimethylarsino-thiosuccinic acid or s-dipropylarsino-1-thioglycerol.. .
Antiseptic, antiseborrheic, exfoliating composition for getting rid of or preventing acne
The invention refers to an antimicrobial, exfoliating and seboregulating hydrosoluble composition comprising a combination of diallyl disulphide modified oxide (ddmo) and alpha hydroxyethanoic acid (glycolic acid), which acts removing bacteria affecting the skin including those caused by acne, said composition also provides deep cleansing, exfoliating action, reduces epidermal cohesion facilitating cellular change, preventing the occurrence of several forms of acne in the skin and additionally producing seboregulating effects by avoiding blockage of sebaceous glands.. .
Grupo Medifarma S.a. De C.v.
Compositions for nanoemulsion delivery systems
The present disclosure provides a pharmaceutically acceptable, stable, and optically clear oil-in-water nanoemulsions (intensity-averaged diameter<100 nm) with an oil phase comprising >10% w/v of long chain triglyceride, total surfactant and cosurfactant concentration less than that of oil phase and without the use of alcohol as cosolvent in the aqueous phase. The nanoemulsions of this disclosure have extremely favorable particle size distribution, optical clarity, and product stability against ostwald ripening with high levels of oil concentrations.
Oral formulations of chemotherapeutic agents
A composition and method of using the composition for treating a patient in need thereof, the composition comprising an oral formulation for enhanced bioavailability of therapeutic agents such as the taxane chemotherapeutic agents. The composition comprises the therapeutic agent and an absorption enhancing agent either co-administered with the agent or administered separately, the therapeutic agent in a polymer matrix resulting in a microbead and including an edible oil resulting in an emulsion.
Method and composition for treating hyperglycemia
Compositions and methods for treating diseases and or disorders, including hyperglycemia and/or diabetes, and obesity in a subject are provided. In particular, a dry powder oral inhalation system is provided comprising, a dry powder composition of glp-1 analogs, including pegylated-glp-1 molecules and a diketopiperazine..
Quick-penetrating soft skin-care cream
The invention pertains to the field of cosmetic and/or dermatological compositions and relates to quick-penetrating skin care compositions for topical application to human skin, containing wax components, carbomers, certain fatty alcohols, emollients, certain fatty acid and fatty alcohol esters, and at least one active ingredient selected from among creatine, allantoin, and/or glycerin. The invention further relates to methods for the production and to uses of such compositions..
Evonik Industries Ag
Stevia compositions are prepared from steviol glycosides of stevia rebaudiana bertoni. The compositions are able to provide a superior taste profile and can be used as sweetness enhancers, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals..
Oil or fat composition and producing same
[solution] the oil or fat composition according to the present invention comprises (i) a palm-based fractionated oil or fat in which the ratio of the content of tripalmitin relative to the content of triglyceride is 70 to 90 wt % and the ratio of the content of unsaturated fatty acids relative to the total content of all of fatty acids is 1 to 8 wt % and (ii) a base oil having a melting point of lower than 10° c., wherein the content of the component (i) is 0.05 to 15 wt % relative to the whole weight of the oil or fat composition and the content of the component (ii) is 85 to 99.95 wt % relative to the whole weight of the oil or fat composition.. .
Use of glyphosate to control clubroot disease
A method of treating a plant growth medium comprising applying a glyphosate pesticide to the plant growth medium. The treatment may prevent, inhibit, reduce and/or treat clubroot disease, caused by infection with plasmodiophora brassicae, in one or more plants grown in the plant growth medium.
Antimicrobial composition for inhibiting microbial organisms and the method thereof
The invention relates to a method of controlling or combating microbial organism by applying an antimicrobial peptide to the microbial organisms, wherein said antimicrobial peptide derived from lilium ‘stargazer’ glycine-rich protein 1. In addition, the present invention provides an antimicrobial composition comprising an antimicrobial peptide of the invention, an additional biocidal agent and pharmaceutically acceptable vehicles, excipients, diluents, and adjuvants..
National Taiwan University
Pesticidal/ovicidal composition and pesticidal/ovicidal method
A pesticidal/ovicidal composition comprising: (a) 50-99.9 parts by mass of a triglyceride containing not less than 50% of oleic acid as a fatty acid component; (b) 0.1-20 parts by mass of a nonionic surface active agent; and (c) 0-30 parts by mass of a glycerin derivative. The composition according to the invention has not only a pesticidal activity but also an ovicidal activity on crop pests, and provides a safe and high pesticidal/ovicidal effect..
Systems and methods for generating, storing, and displaying anatomical maps
A method of generating an anatomical map includes acquiring geometry information and biological information for an anatomical region. The geometry and biological information are associated with each other, for example by associating measured biological attributes with the anatomical locations at which they were measured.
St. Jude Medical, Cardiology Division, Inc.
Photograph billpay tagging
Tools for photograph billpay tagging of a digital image are provided. The digital image may correspond to a portion of text positioned upon a medium.
Bank Of America Corporation
Mutant yeast strain with decreased glycerol production
The disclosure relates to the use of a mutant ssk1 gene encoding a truncated ssk1 protein for the construction of a mutant yeast strain with decreased glycerol production, when compared to the wild-type strain. It relates further to the use of such strains for high-yield bioethanol production, especially in high osmotic media, or on cellulosic hydrolysates, where normal yeast strains do produce a significant amount of glycerol..
Katholieke Universiteit Leuven, K.u.leuven R&d
Microorganisms and processes for the conversion of glycerol to isoprene
The present invention provides non-naturally occurring microorganisms that have been modified to produce isoprene from glycerol. The microorganisms include one of several glycerol dissimilation pathways and one of several isoprene production pathways..
Glycos Biotechnologies, Inc.
Pharmaceutical composition for treating liver diseases
The present invention relates to a pharmaceutical composition for treating liver diseases, comprising a mirna mimic containing a single strand rna molecule of hsa-mir-21-3p (seq id no: 35). The mirna mimic of the present invention can be used to treat liver diseases through regulating the expression of methionine adenosyltransferase 2a and 2b (mat2a and mat2b), acetyl-coa carboxylase 1 and 2 (acaca and acacb), diglyceride acyltransferase 2 (dgat2), and so on.
Antisense polynucleotides to induce exon skipping and methods of treating dystrophies
Antisense polynucleotides and their use in pharmaceutical compositions to induce exon skipping in targeted exons of the gamma sarcoglycan gene are provided, along with methods of preventing or treating dystrophic diseases such as limb-girdle muscular dystrophy. One aspect the disclosure provides an isolated antisense polynucleotide wherein the polynucleotide specifically hybridizes to an exon target region of a gamma sarcoglycan rna, wherein the exon is selected from the group consisting of exon 4 (seq id no:1), exon 5 (seq id no: 2), exon 6 (seq id no: 3), exon 7 (seq id no: 4) and a combination thereof.
The University Of Chicago
Ultrapure hypoallergenic solutions of sacrosidase
One aspect provides an ultrapure, hypoallergenic sacrosidase. Another aspect provides a solution of sacrosidase in about 1:1 glycerol/water having an enzymatic activity of at least about 7500 iu/ml and a residual papain concentration that does not include an allergic reaction in a human patient when given a dose of about 2.0 ml/day..
Qol Medical Llc
Porous gels and uses thereof
Hydrogels having a porosity of at least about 5%, comprising a first polymeric material comprising a polymer derived from a monomer with a vinyl functionality, and a second polymeric material having a polyglycol other than polyethylene glycol are described. A method of forming a porous hydrogel, by mixing in a reaction vessel, a mixture comprising a monomer having a vinyl functionality, a crosslinker, an organic solvent, a first polymeric material comprising polyacrylic acid and a second polymeric material comprising a polyglycol other than polyethylene glycol, and mixing the mixture to form the hydrogel having a porosity of at least about 5%.
Dielectric fluids compositions and methods
Green compositions and technologies are provided. In an embodiment, the present invention provides a method of providing dielectric fluids, heat transfer fluids or cooling fluids.
Acrylic adhesive for assembling elements contacting biological substances
The present invention relates to an adhesive composition comprising (1) at least one polyol tri(meth)acrylate monomer selected from the group consisting of ditrimethylolpropane triacrylate (ditmptta), tris-(2-hydroxyethyl)-isocyanurate triacrylate (theicta) dipentaerythritol triacrylate (dipeta), ethoxylated trimethylolpropane triacrylate (tmpeota), propoxylated trimethylolpropane triacrylate, (tmppota), ethoxylated pentaerythritol triacrylate (peteoia), propoxylated glyceryl triacrylate (gpta), pentaerythritol triacrylate (peta), trimethylolpropane triacrylate (tmpta) and modified pentaerythritol triacrylate, triethyleneglycol trimethacrylate (tiegtma), tetraethyleneglycol trimethacrylate (ttegtma), polyethyleneglycol trimethacrylate hexane trimethacrylate (httma) ethoxylated bisphenol a trimethacrylate, and trimethylolpropane trimethacrylate (tmptma), (2) at least one polyalkylene glycol mono(meth)acrylate monomer selected from the group consisting of polypropylene glycol monomethacrylate, polyethylene glycol monomethacrylate, polyethylene glycol-polypropylene glycol monomethacrylate, polypropylene glycol monoacrylate, polyethylene glycal monoacrylate, polypropylene glycol-polytrimethylene monoacrylate, polyethylene glycol-polytetramethylene glycol monomethacrylate, methoxypolyethylene glycol monomethacrylate, yerfluoroalkylethyl-polyoxyalkylene monomethacrylate, and combinations thereof, and (3) at least one radical initiator selected from the group of initiators sensitive to uv and/or blue radiation (photoinitiator) and thermal initiators (thermoinitiator). The adhesive composition is used for assembling elements made of plastic materials, like pmma or san, or inorganic materials, like glass or metals, employed for manufacturing of devices for the distribution of containment of biological substances..
Sicpa Holding Sa
Polyester films and methods for manufacturing the same
, wherein x is independently hydroxyl, carboxyl or —coor, and r is c1-6 alkyl. The molar ratio between terephthalic acid and ethylene glycol ranges is between about 50:50 and 30:70.
Method for adhering hydrogels
There is provided a method for bonding together hydrogels by interposing a polyalkylene glycol between the gel surfaces to be bonded together of hydrogels. A method for bonding together hydrogels of the same type or different types, the method including: interposing a polyalkylene glycol between gel surfaces to be bonded together of the hydrogels and joining together the gel surfaces..
Novel far red fluorescent protein
The present invention relates to a nucleic acid molecule encoding a polypeptide having a fluorescence emission activity at a wavelength of at least 630 nm, wherein said nucleic acid molecule is selected from the group consisting of (a) a nucleic acid molecule encoding a polypeptide having the amino acid sequence of seq id no: 1; (b) a nucleic acid molecule encoding a polypeptide having the amino acid sequence of seq id no: 1, with the exception that in the polypeptide of seq id no: 1 (b-i) glutamic acid at the position corresponding to position 16 is replaced by glycine; (b-ii) asparagine at the position corresponding to position 125 is replaced by aspartic acid; and/or (b-iii) lysine at the position corresponding to position 185 is replaced by asparagine; (c) a nucleic acid molecule encoding a polypeptide having at least 94% sequence identity to the polypeptide encoded by the nucleic acid molecule of (a) or (b); (d) a nucleic acid molecule having the nucleotide sequence of seq id no: 2; (e) a nucleic acid molecule having the nucleotide sequence of seq id no: 2, with the exception that said nucleic acid molecule has (e-i) at the positions corresponding to positions 48 to 50 of seq id no: 2 a nucleotide triplet selected from the group consisting of ggt, ggc, gga and ggg; or (e-ii) at the positions corresponding to positions 375 to 377 of seq id no: 2 a nucleotide triplet selected from the group consisting of gat and gac; and/or (e-iii) at the positions corresponding to positions 555 to 557 of seq id no: 2 a nucleotide triplet selected from the group consisting of aat and aac; (f) a nucleic acid molecule having the nucleotide sequence of (d), (e) or (f), wherein each thymine is replaced by uracile; and (g) a nucleic acid molecule degenerate with respect to the nucleic acid molecule of (d) or (e). The present invention further relates to a vector comprising the nucleic acid molecule of the invention and a non-human host transformed with the vector of the invention.
Helmholtz Zentrum München - Deutsches Forschungszentrum Für Gesundheit Und Umwelt Gmbh
Novel compounds as diacylglycerol acyltransferase inhibitors
This invention relates to novel compounds which are inhibitors of acyl coenzymea: diacylglycerol acyltransferase 1 (dgat-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the prevention or treatment of diseases related to dgat-1 dysfunction or where modulation of dgat-1 activity may have therapeutic benefit including but not limited to obesity, obesity related disorders, hypertriglyceridemia, hyperlipoproteinemia, chylomicronemia, dyslipidemia, non-alcoholic steatohepatitis, diabetes, insulin resistance, metabolic syndrome, hepatitis c virus infection and acne or other skin disorders.. .
Glaxosmithkline Intellectual Property (no.2) Limited
Process for making certain epoxidized fatty acid ester plasticizers
A process is described for making an epoxidized fatty acid ester material useful as a plasticizer for flexible pvc applications, comprising: transesterifying a low moisture epoxidized natural fat or oil with a first alcohol in a first transesterification step; then, after the resultant product mixture phase separates into an epoxidized fatty acid ester phase and a second phase comprising byproduct glycerol, substantially removing the second phase; combining epoxidized fatty acid esters in the epoxidized fatty acid ester phase with more of the first alcohol and with a second alcohol which includes 5 to 7 members in a ring structure and carrying out a second transesterification step, while continuously removing first alcohol during the second transesterification step in order to drive the reaction with the second alcohol toward the desired epoxidized fatty acid ester material from the second alcohol, but without large molar excesses of the second alcohol being required.. .
Archer Daniels Midland Company
Process to obtain mixtures of imidazolines and corrosion inhibitors from coffee waste
The biphasic extraction from coffee waste without a prior drying process, to obtain coffee oil, which is transesterified with koh catalyzed methanol to produce mixtures of glycerol free methylic esters, also known as coffee oil biodiesel, which is subjected to an aminolysis reaction with aminoethylethanolamine (aeea) by heating to 140-160° c. At atmospheric pressure with a subsequent dehydration reaction at the same temperature but at a reduced pressure of 200 to 300 mmhg, in order to achieve cyclization of the intermediary amides into the corresponding imidazolines.
Corrosion Y Proteccion Sa De Cv
Divalent ion removal from monoethylene glycol (meg) feed streams
A system and process for removing divalent ions from a meg feed stream is presented. The system includes a chemical treatment tank where chemicals are mixed with the feed stream to form insoluble carbonate and hydroxide salts.
Cameron Solutions, Inc.
Method for preparing a composition rich in lutein produced by microalgae
The invention relates to a method for preparing a composition rich in lutein produced by microalgae, particularly microalgae belonging to the chlorella genus, more specifically produced by chlorella vulgaris, characterized in that said method includes the sequence of the following steps: 1) preparing a cell lysate from the microalgae biomass; 2) treating the lysed microalgae biomass with a polar solvent, preferably ethyl acetate, in order to obtain an oleoresin containing the lutein and the lipids from the initial biomass; 3) extracting the oleoresin obtained in step 2) by means of a non-polar solvent, here a fluid at supercritical pressure, in order to obtain a fraction rich in non-polar lipids, mainly consisting of triglycerides, and an insoluble fraction rich in lutein; and 4) recovering the thus lutein-enriched fraction.. .
Process for the manufacture of propanediol
A process for manufacturing 1,3-propanediol by reacting glycerol with hydrogen in the presence of a supported catalyst, the supported catalyst comprising at least one iridium compound and at least one rhenium compound, both compounds being supported on a zeolite, wherein the zeolite exhibits an mfi, a mel, a bea, a mor, a fau, a fer, a mww, a cha, a lta, a ato or a ael framework type, and wherein the said zeolite is at least partially in the hydrogen form.. .
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Gly topics: Door Assembly, Swimming Goggles, Transverse, Alkoxylate, Fluoropolymer, Air Cleaning, Rotor Shaft, Aspect Ratio, Disconnect, Synchronization, Remote Control, Ethylene Glycol, Surfactant, Combustion, Steviol Glycosides
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