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|| List of recent Gly-related patents
| Thermoelectric material and thermoelectric module|
A thermoelectric material is manufactured by a manufacturing process including annealing at an annealing temperature from 125° c. To 200° c.
National Institute Of Advanced Industrial Science And Technology
| Solid electrolytic capacitor and manufacturing method thereof|
A high voltage proof solid electrolytic capacitor that can prevent deterioration of voltage proof property due to lead-free reflow etc. And a manufacturing method thereof are provided.
Nippon Chemi-con Corporation
| Image text search and retrieval system|
Glyphs, symbols, or non-symbols are selected and become a “search term.” the search term is normalized and then depicted upon a grid for marking. Marked search term areas may be measured from a center point.
| Method and device for realizing chinese character input based on uncertainty information|
The present invention provides a method and device for realizing chinese character input based on uncertainty information, wherein the method comprises: receiving input information from a user; extracting at least two types of uncertainty information of chinese characters to be input, from the input information; and, determining the matched chinese characters according to the at least two types of uncertainty information and outputting the matched chinese character(s). The device comprises a receiving module, an extracting module and a matching module.
Samsung Electronics Co., Ltd.
| Preventing website content plagiarism and indexing using a character and font glyph mapping scheme|
The invention uses alternate mapping between characters and font glyphs to prevent website content from being plagiarized or indexed by a third party. Specifically, a font glyph file may be created comprising a plurality of font glyphs.
Go Daddy Operating Company, Llc
| Positive-type photosensitive resin composition, producing semiconductor device including cured film using the same|
The present invention provides a positive-type photosensitive resin composition capable of obtaining a cured film which exhibits low warpage, and is also excellent in high sensitivity and high resolution during firing at a lower temperature of 250° c. Or lower.
Toray Industries, Inc.
| Gram staining method with improved decolorization of the crystal violet-iodine complex from gram negative bacteria|
Provided herein are methods of staining biological material for the purpose of detecting, and in some examples also identifying, microorganisms. Methods of gram staining bacteria using a slow-acting decolorizing formulation, such as one that includes 1,2-propandiol or ethylene glycol, can be used to extend the time of the decolorizing step, and thus permit automation of the gram staining method.
Ventana Medical Systems, Inc.
| Gallium extraction agent and gallium extraction method|
Provided are an extraction agent and extraction method that selectively extract and, at a low cost, recover gallium from an acidic solution containing gallium and zinc. The gallium extraction agent comprises an amide derivative represented by general formula (1).
Sumitomo Metal Mining Co., Ltd.
| Production of 1,3-propanediol in cyanobacteria|
Cyanobacterial host cells are modified to produce useful chemicals such as 1,3-propanediol and glycerol.. .
Algenol Biofuels Inc.
| Methods for enhancing the degradation or conversion of cellulosic material|
The present invention relates to processes for degrading a cellulosic material and for producing substances from the cellulosic material using recombinant glycoside hydrolase of family 61 (gh61) from trichoderma.. .
Production of renewable diesel and propylene
Feeds containing triglycerides are processed to produce a diesel fuel product and propylene. The diesel product and propylene are generated by deoxygenating the triglyceride-containing feed using processing conditions that enhance preservation of olefins that are present in the triglycerides.
Exxonmobil Research And Engineering Company
The invention relates to a pharmaceutical composition comprising a glycoprotein comprising the fc domain of an antibody, or a fragment thereof, comprising an asn (asparagine) residue and an oligosaccharide structure attached thereto, wherein said oligosaccharide structure has a structure according to formula i, wherein at least 10% of the oligosaccharide structures attached to glycoproteins in the composition consist of oligosaccharide structures according to formula i.. .
Glykos Finland Oy
Glycoproteins with anti-inflammatory properties
Glycoproteins having particular sialylation patterns, and methods of making and using such glycoproteins, are described.. .
Momenta Pharmaceuticals, Inc.
Novel azabenzimidazole tetrahydropyran derivatives
Novel compounds of the structural formula (i) are activators of amp-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the ampkactivated protein kinase. The compounds of the present invention may be useful in the treatment of type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension..
Merck Sharp & Dohme Corp.
Coatings for medical devices
A method and device for local delivery of a water-insoluble therapeutic agent to the tissue of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with a non-durable coating which includes an amphiphilic polymer or copolymer, in embodiments polyethylene glycol, having a substantially water-insoluble therapeutic agent dispersed therein.
Mucoadhesive polymers having vitamin b partial structures
Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol substructures to them. By the transformation of free thiol groups on such polymers in disulfides with mercaptonicotinamides or mercaptopyridoxins these thiol groups become comparatively more reactive resulting in significantly improved mucoadhesive properties.
Croma Pharma Gmbh
Immunization with rabies virus vector expressing foreign protein antigen
An immune response in a subject is elicited by a regiment comprising immunization with an attenuated recombinant rabies virus encoding at least one foreign protein antigen, and booster immunization with the at least one foreign protein antigen in a vehicle that does not contain adjuvant. The foreign protein antigen may comprise a prion protein antigen, a cancer-associated antigens, a viral antigen, a bacterial antigens, or a protozoal antigen.
Thomas Jefferson University
Recombinant modified vaccinia virus ankara (mva) respiratory syncytial virus (rsv) vaccine
Provided herein are recombinant modified vaccinia virus ankara (mva) strains as improved vaccines against infection with respiratory syncytial virus (rsv virus) and to related products, methods and uses. Specifically, provided herein are genetically engineered recombinant mva vectors comprising at least one nucleotide sequence encoding an antigenic determinant of an rsv membrane glycoprotein and at least one nucleotide sequence encoding an antigenic determinant of an rsv nucleocapsid protein.
Bavarian Nordic A/s
Glycan compositions, processes for preparing the same and their uses as a drug
Glycan compositions, processes for preparing the same and their uses as a drug.. .
Universite Lille 1 Sciences Et Technologies
Methods and compositions for modulating gastrointestinal bacteria to promote health
Methods and compositions for treating medical conditions or improving health in which the composition is ingested in an amount sufficient to modify the proportion of bacteria in a gut microbiome of the individual ingesting the composition. The composition may comprise polydextrose or soluble com fiber, for example.
General Mills, Inc.
Use of cordycepin in manufacture of medicaments for anti-depression
The present invention provides the use of cordycepin or derivatives thereof in manufacture of medicaments for antidepression, said derivatives mean pharmaceutically acceptable salts, esters of crodycepin or glycosides formed by cordycepin and saccharides.. .
Beijing Gragen Biotechnology Co. Ltd.
Use of novel monosaccharide-like glycylated sugar alcohol compositions for designing and developing anti-diabetic drugs
This invention is related to a novel sugar-like chemical composition and its use for diabetes therapy. Particularly, the present invention teaches the use of monosaccharide-like glycylated sugar alcohol compounds to block or reduce sugar absorption in diabetes patients, so as to prevent the risk of hyperglycemia symptoms.
Multi-component formulation for improving neurological function
In certain embodiments multi-component formulations are provided where the formulations comprise a first component comprising one or more vitamins selected from the group consisting of one or more b vitamins, vitamin c, vitamin d, vitamin e, co-enzyme q10, vitamin k, and folate; a second component comprising one or more elements selected from the group consisting of selenium, lithium, magnesium, and molybdenum; a third component comprising one or more omega-3 fatty acids; and a fourth component comprising one or more amino acids selected from the group consisting of trimethylglycine, n-acetyl cysteine, s-adenosyl methionine, l-tryptophan, and glutathione.. .
Buck Institute For Research On Aging
Highly soluble rebaudioside d
The invention relates to a process for producing highly soluble compositions containing purified steviol glycosides from stevia rebaudiana bertoni plant extract, more particularly rebaudioside d. Obtained highly soluble compositions are useful as non-caloric sweeteners or in combination with sugar or high intensity sweeteners in edible and chewable compositions such as beverages, confectionaries, bakery products, chewing gums and the like..
Edible water-in-oil emulsion and a process for preparing such emulsion
The invention relates to an edible water-in-oil emulsion comprising a fat-phase comprising a first hardstock and a second hardstock, wherein said fat-phase has a total amount of hardstock of from 2 to 60 wt. %, based on the total weight of the fat-phase, and a water-phase, wherein part of the water-phase is dispersed as droplets, wherein the droplets are stabilized by said first hardstock; and wherein part of the water-phase is dispersed as droplets, wherein the droplets are stabilized by said second hardstock, wherein said first hardstock comprises more than 25% of hhh-triglycerides, and a combined amount of h2u and h2m triglycerides of not more than 110% of the hhh-triglycerides of said first harstock, wherein said second hardstock comprises less than 22% of hhh-triglycerides, and a combined amount of h2u and h2m triglycerides of more than 140% of the hhh-triglycerides of said second hardstock, wherein h denotes saturated chains with 16 or more carbon atoms or an elaidic acid residue, wherein u denotes unsaturated chains and wherein m denotes saturated chains with 14 or less carbon atoms.
Conopco, Inc., D/b/a Unilever
Method of delivery of bio-active agents to plant cells by using nano-sized materials as carriers
A method for regulating properties of a plant, includes: providing a nanoagent having at least one nanocomposite; and delivering the nanoagent to the plant. The nanocomposite has at least one gold nanorod, a silver layer coated on an outer surface of the gold nanorod, a pegylated layer coated on the silver layer, and an active layer conjugated to the pegylated layer.
Board Of Trustees Of The University Of Arkansas
Lithium secondary battery
A lithium secondary battery is provided, which exhibits a large overcharge tolerance even after rapid charge-discharge cycling. The lithium secondary battery is constituted by a battery case hosing electrode assembly having a positive electrode and a negative electrode, and also housing a nonaqueous electrolyte solution including a supporting salt.
Toyota Jidosha Kabushiki Kaisha
Printing system and printing control program
A host computer (100), wherein the computer is equipped with a font availability determination unit (6) for determining whether or not the font and glyph image specified for characters to be printed are available in a printer (200) and an outline image transmission unit (9) for transmitting an outline image of the specified font to the printer (200) in cases in which it is determined that the font and the like are not available in the printer, and by transmitting the outline image to the printer (200) to print, it is possible to print using a character format which is infinitely close to the font specified by the host computer (100) even in cases in which the specified font and the like are not available in the printer (200).. .
Font process method and font process system
When opening a document, the character codes of all characters in the document are uploaded to a font server, then all possible glyphs corresponding to the uploaded character codes of characters tagged with a font are selected from a font file which stores a plurality of glyphs of the font to form a glyph subset. And the glyph subset is then downloaded..
Arphic Technology Co., Ltd.
Quantifying local inflammatory activity and its use to predict disease progression and tailor treatments
This invention relates to a method of predicting progression of an inflammatory condition in a subject, which involves providing a medium comprising hyaluronan or a fragment thereof; contacting the medium with a fluid sample from a subject with an inflammatory condition, where the fluid sample comprises proteins or proteoglycans and a transfer agent; incubating the fluid sample with the medium under conditions effective for the transfer agent in the fluid sample to mediate transfer of heavy chains from the proteins or proteoglycans to the hyaluronan or a fragment thereof to form a complex; detecting, using an antibody, occurrence levels of the complex; and comparing occurrence levels of the complex from said detecting to a reference standard to predict progression of an inflammatory condition in the subject. Also disclosed are methods of tailoring treatment of an inflammatory condition and quantifying local inflammatory activity in a body fluid..
New York University
Method for detecting at least one mechanism of resistance to glycopeptides by mass spectrometry
The present invention relates to a method of detection, for at least one microorganism contained in a sample, of at least one marker of resistance to a glycopeptide, including the detection, by mass spectrometry, of at least one peptide or protein of said microorganism. Preferably, the glycopeptide is vancomycin.
Biomarkers for diagnosis of diabetes and monitoring of anti-diabetic therapy
The present invention relates to the use of n-linked glycan profiles of blood or blood component proteins as biomarkers for diagnosing diabetes mellitus and for monitoring the efficacy of anti-diabetic therapy. Specifically, the present invention relates to detecting changes in the amounts of n-linked glycans as diagnostic biomarkers for diabetes mellitus and as indicators of the efficacy of anti-diabetic therapy over time..
Sumitomo Bakelite Co., Ltd.
Biomarkers for type 2 diabetes
The present invention relates to a method of identifying a predisposition for developing type 2 diabetes mellitus in a subject, said method comprising the step of assessing in a sample obtained from said subject the amount of one or more metabolite(s) selected from (a) a first group comprising the metabolites glycine, lysophosphatidylcholine acyl c18:2, lysophosphatidylcholine acyl c17:0, lysophosphatidylcholine acyl c18:0, lysophosphatidylcholine acyl c18:1, phosphatidylcholine acyl-alkyl c34:2, phosphatidylcholine acyl-alkyl c36:2, phosphatidylcholine acyl-alkyl c36:3 and isobaric metabolites having the same molecular mass as glycine, lysophosphatidylcholine acyl c18:2, lysophosphatidylcholine acyl c17:0, lysophosphatidylcholine acyl c18:0, lysophosphatidylcholine acyl c18:1, phosphatidylcholine acyl-alkyl c34:2, phosphatidylcholine acyl-alkyl c36:2 or phosphatidylcholine acyl-alkyl c36:3 but different chemical formula; and/or (b) a second group comprising the metabolite acetylcarnitine c2 and an isobaric metabolite having the same molecular weight as acetylcarnitine c2 but different chemical formula; wherein a decrease in the amount of a metabolite selected from said first group or an increase in the amount of a metabolite selected from said second group as compared to the amount of the corresponding metabolite(s) of a control is indicative of a predisposition to develop type 2 diabetes mellitus. Further, the invention relates to a method of identifying a compound capable of preventing type 2 diabetes mellitus and diseases associated therewith or serving as a lead compound for developing a compound capable of preventing type 2 diabetes mellitus and diseases associated therewith and a method of selecting a therapy to prevent type 2 diabetes mellitus.
Helmholtz Zentrum Munchen
Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
The invention relates to poly-amide bonded hydrophilic interaction chromatography (hilic) stationary phases and novel hilic methods for use in the characterization of large biological molecules modified with polar groups, known to those skilled in the art as glycans. The invention particularly provides novel, poly-amide bonded materials designed for efficient separation of large biomolecules, e.g.
Waters Technologies Corporation
Diagnostic tools for herbicide resistance in plants
Embodiments of the present disclosure relate generally to kits for identifying herbicide resistant plants and methods for determining whether a plant is herbicide resistant. The methods are based on the discovery that some genes are over-expressed or under-expressed in herbicide resistant plants when compared to herbicide-sensitive plants prior to application of the herbicide.
Purdue Research Foundation
Method for determining breast cancer
The present invention relates to: a breast cancer marker which is selected from the group consisting of carboxypeptidase n subunit 2, extracellular matrix protein 1, serum amyloid p component, nebulin, complement component c8 α chain, apolipoprotein l1, flavin reductase, catalase, carbonic anhydrase 2, apolipoprotein c—i, nuclear pore glycoprotein 210, superoxide dismutase [cu—zn], bisphosphoglycerate mutase, carbonic anhydrase 1 and peroxiredoxin-2; a method for determining breast cancer, which comprises detecting the breast cancer marker in a sample and determining breast cancer on the basis of the results of the detection; and a kit for use in the method.. .
Production of sialylated n-glycans in lower eukaryotes
The present invention relates to eukaryotic host cells which have been modified to produce sialylated glycoproteins by the heterologous expression of a set of glycosyltransferases, including sialyltransferase and/or trans-sialidase, to become host-strains for the production of mammalian, e.g., human therapeutic glycoproteins. Novel eukaryotic host cells expressing a cmp-sialic acid biosynthetic pathway for the production of sialylated glycoproteins are also provided.
Recombinant bacteria comprising novel sucrose transporters
Recombinant bacteria capable of metabolizing sucrose are described. The recombinant bacteria comprise in their genome or on at least one recombinant construct, a novel nucleotide sequence encoding a polypeptide having sucrose transporter activity and a nucleotide sequence encoding a polypeptide having sucrose hydrolase activity.
E.i. Du Pont De Nemours And Company
Increased caloric and nutritional content of plant biomass
As described herein, plants expressing algal diacylglycerol acyltransferase type two (dgtt) from heterologous nucleic acids can alter acyl carbon partitioning in plant vegetative tissues and increase acyl-coa-dependent triacylglycerol synthesis, thereby increasing the lipid content of the plants' tissues.. .
N-glycan core beta-galactosyltransferase and uses thereof
The present invention relates to new galactosyltransferases, nucleic acids encoding them, as well as recombinant vectors, host cells, antibodies, uses and methods relating thereto.. .
Process for producing ethyl esters of polyunsaturated fatty acids
The present invention relates to a process for producing ethyl esters of polyunsaturated fatty acids, comprising transesterifying triacylglycerols in extracted plant lipid.. .
Nuseed Pty Ltd
Lubricating oil composition for internal combustion engines
A lubricating oil composition for internal combustion engines containing a base oil mixture with specific properties and a monoglyceride with a specific structure. The lubricating oil composition of the present 5 invention, as well as providing outstanding wear resistance and fuel economy, causes condensed water etc.
Shell Oil Company
The present disclosure concerns a lubricant composition including: at least one base oil; and at least two glycerol esters e1 and e2, ester e1 being an ester of glycerol and of a c12-c26 carboxylic acid and ester e2 being an ester of glycerol and of a c4-c10 carboxylic acid. The lubricant composition has good friction properties, and the use thereof promotes fuel savings..
Total Marketing Services
Preparation polymeric phase-change material
The invention relates to a preparation method of a polymeric phase-change material, comprising: using 1, 2 or 3 of (meth)acrylate poly(ethylene glycol) n-alkyl ether ester as a raw material, wherein the (meth)acrylate poly(ethylene glycol) n-alkyl ether ester has a structural general formula of ch2═c(ch3)—coo(ch2o)mcnh2+1 or ch2═ch—coo(ch2ch2o)mcnh2+1, m=1 to 100, and n=10 to 50; washing the raw material with a solution of sodium hydroxide, potassium hydroxide, sodium carbonate or potassium carbonate having a mass percentage of 1% to 10% to remove a polymerization inhibitor, and subjecting reduced-pressure distillation, and then to a polymerization reaction by adopting one of the following process; 1. Polymerization reaction initiated by irradiation; 2.
Tianjin Polytechinc University
Polymer network material comprising a poly(glycidyl ether) structure, its production and use
The present invention is related to novel preparative methods to a novel class of polymer network materials with a highly branched poly(glycidyl ether) (pge) structure. Said polymer networks are prepared by a simple procedure involving ring-opening polymerisation and the method is applicable to a wide range of glycidyl ether containing monomers.
Helmholtz-zentrum Geesthacht Zentrum Fuer Material- Und Kuestenforschung Gmbh
Cytoplasmic tail modifications to boost surface expression and immunogenicity of envelope glycoproteins
The invention provides compositions and methods for enhanced expression of a viral envelope protein. The invention provides a composition comprising a cytoplasmic tail modification to enhance surface expression of both hiv and non-hiv viral envelope proteins as wells as other membrane associated proteins resulting in increased immunogenicity..
The Trustees Of The University Of Pennsylvania
Modified compstatin with peptide backbone and c-terminal modifications
Compounds comprising peptides capable of binding c3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.
The Trustees Of The University Of Pennsylvania
Synthesis of diverse glycosylphosphatidylinositol glycans from toxoplasma gondii and their application as vaccines and diagnostics
The present invention relates to the synthesis of gpi-related surface antigens of the parasite toxoplasma gondii (t. Gondii) and the resulting products obtained.
Max-planck-gesellschaft Zur Förderung Der Wissenschaften E.v.
Novel azabenzimidazole tetrahydrofuran derivatives
Novel compounds of the structural formula (i) are activators of amp-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the ampk-activated protein kinase. The compounds of the present invention may be useful in the treatment of type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension..
Merck Sharp & Dohme Corp.
Additive including cross-linked polycarboxylic copolymer and cement composition comprising the same
Disclosed are an additive of a cement composition including a cross-linked polycarboxylic copolymer and a cement composition including the same. More particularly, an additive of a cement composition including a polycarboxylic copolymer and/or a salt thereof, wherein the polycarboxylic copolymer is a copolymer of a monomer mixture including an alkoxy polyalkylene glycol mono(meth)acrylic acid ester-based monomer, a (meth)acrylic acid-based monomer, and a cross-linking agent containing 5 to 20 alkylene oxide groups and having two or more acrylate groups or vinyl groups, and a cement composition including the same are disclosed.
Lg Chem, Ltd.
Dispersion and forming hydrogel
There is provided a dispersion containing a lipid peptide type compound useful as a low molecular weight gelator and a solvent capable of dissolving the lipid peptide type compound at a lower temperature. There is provided also a dispersion from which a hydrogel can be formed by a simpler method and from which a gel can be obtained as a gel having high thermal stability, and provide a method for forming the gel.
Nissan Chemical Industries, Ltd.
Contrast agents, methods for preparing contrast agents, and methods of imaging
Provided is a protein contrast agent for enhancing an mri image and comprising a polypeptide having a conformation presenting at least five oxygen atoms positioned to chelate at least one paramagnetic metal ion such as gd3+, each oxygen atom being between about 2 angstrom units and about 5 angstrom units from the metal ion; the metal ion has at least one water molecule electrostatically interacting a distance of less than about 10 angstrom units a target-specific moiety conjugated thereto, at least one polyethylene glycol molecule, and a paramagnetic metal ion. Also provided is a method of obtaining an enhanced mri image using the protein contrast agent to a t2/t1 or t1/t2 intensity ratio of the mri image; and (d) obtaining an image of the t2/t1 or t1/t2 intensity ratio..
Georgia State University Research Foundation, Inc.
Interferon-alpha fusion protein in which cytoplasmic transduction peptide and polyethylene glycol are bonded to one another
The present invention relates to ifn-α fusion protein in which a cytoplasmic transduction peptide (ctp) and polyethylene glycol (peg) are bonded to an ifn-α protein. The ifn-α fusion protein of the present invention is characterized in that the specific activity of interferon remains high, the half-life of the inf-α fusion protein is extended when delivered in vivo, and the mobility of the interferon in a liver is improved.
Jw Creagene Inc.
Methods for introducing mannose 6 phosphate and other oligosaccharides onto glycoproteins and applications thereof
Methods to introduce highly phosphorylated mannopyranosyl oligosaccharide derivatives containing mannose-6-phosphate (msp), or other oligosaccharides bearing other terminal hexoses, to carbonyl groups on oxidized glycans of glycoproteins while retaining their biological activity are described. The methods are useful for modifying glycoproteins, including those produced by recombinant protein expression systems, to increase uptake by cell surface receptor-mediated mechanisms, thus improving their therapeutic efficacy in a variety of applications..
Targeted oesophageal administration of zn-alpha2-glycoproteins (zag), methods and formulations thereof
The invention provides formulations and methods for ameliorating symptoms associated with metabolic disorders, such as hypoglycemia, obesity, diabetes, and the like by targeted administration to the oesphagus of a subject of zn-α2-glycoproteins or a functional fragment thereof, alone or in combination with additional agents, such as β adrenergin receptor agonists, β adrenergin receptor antagonists, and/or glycemic control agents.. .
Agents, methods, and devices for affecting nerve function
Agents, methods, and devices for affecting nerve function are described. One embodiment of an agent includes a cardiac glycoside, an ace inhibitor, and an nsaid.
Northwind Medical, Inc.
Patches, formulations, and associated methods for transdermal delivery of drugs
The present invention is drawn to transdermal drug formulations, transdermal patches incorporating such formulations, as well as associated methods. The formulations can include about 0.3 wt % to about 5 wt % of a drug, such as risperidone, about 4 wt % to about 30 wt % water, about 10 wt % to about 40 wt % glycerol, about 0.5 wt % to about 6 wt % oleyl alcohol.
Nuvo Research Inc.
Trans-clomiphene formulations and uses thereof
The present invention provides iraws-clomiphene and pharmaceutically acceptable salts and solvates thereof, characterized in that trans-clomiphene is in particulate form having a specific size range. The invention is also directed to pharmaceutical compositions comprising or formulated using trans-clomiphene or pharmaceutically acceptable salts and solvates having a specified size range and their use in treating disorders including secondary hypogonadism, type 2 diabetes, elevated cholesterol, elevated triglycerides, wasting, lipodystrophy, female and male infertility, benign prostate hypertrophy, prostate cancer, breast cancer, ovarian cancer and endometrial cancer..
Repros Therapeutics Inc.
Immediate release film coatings containing medium chain glycerides and substrates coated therewith
The present invention is directed to immediate release film coating compositions for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which contain medium chain glycerides as detackifiers. The film coating compositions can be applied either directly to a substrate or after the substrate has been coated with a subcoat.
Bpsi Holdings, Llc
Water activated shaving wipe
A solvent activated shaving wipe includes a substrate, such as a cloth having a generally porous construction. The shaving wipe includes a dehydrated shaving cream composition applied or impregnated into the substrate that is dry from the point of manufacturing, packaging, and distribution.
A cosmetic has a polymer (a) having a content of an oxyalkylene unit and/or a glycerin unit of 0.5% by mass or more and under 5.0% by mass; and a polymer (b) having a content of an oxyethylene unit and/or a glycerin unit of 5.0% by mass or more and 20.0% by mass or less, the polymer (a) and the polymer (b) being a crosslinking organopolysiloxane polymer obtained by reacting organohydrogen polysiloxane having two or more hydrogen atoms bonded to a silicon atom in one molecule and polyoxyalkylene and/or polyglycerin having two or more aliphatic unsaturated bonds in one molecule, wherein the mass ratio of the polymer (a) to the polymer (b) is 5:95 to 60:40.. .
Shin-etsu Chemical Co., Ltd.
High saturated fat mayonnaise
A mayonnaise product in which the oil phase includes a combination of medium chain triglyceride (mct) oil and a saturated fat such as butter oil, coconut oil, or palm oil, and further incombination with a high oleic oil. The mct and high oleic oil reduces crystallization of the saturated fat when cooled, and consequently this improves emulsion stability.
Stable mix of ingredients for a frozen dessert
The invention relates to a shelf-or chilled-stable mix of food ingredients for the preparation of a frozen dessert, wherein i) the ingredients mix is in a non-frozen state and contained in an aseptic, closed, preferably sealed, packaging, and wherein ii) the ingredient mix comprises propylene glycol monoester of fatty acid, preferably propylene glycol monostearate (pgms) as sole emulsifier or in combination with at least one further emulsifier for frozen desserts; iii) the salt content of the non-frozen mix is at least 70 mg/100 g product, and iiii) the non-frozen mix having a total solids content of less than 30%, preferably from 20 to 28%, and wherein optionally the ingredient mix may be aerated. The invention also relates to a method of making such a product..
Insect repellent surface composition
Embodiments of the invention relate to a pest-control composition comprising at least one active ingredient and at least two other ingredients; wherein the at least one active ingredient is selected from the group consisting of geraniol, nootketone, amyl cinnamaldehyde, catnip, wintergreen, carvacrol, d-limonene, orange oil, lauric acid, alpha pinene, mint, cornmint oil, lemon oil, eucalyptus, eugenol, peppermint, lemongrass oil, and terpenes; and wherein the at least two other ingredients are selected from the group consisting of 2-propanol, alcohol, ethanol, monobutyl ether, ethylene glycol, terpenes, ethoxylated alcohol, dodecanol, ammonia, soap, lauryl polyglucose, polyethylene glycol, sodium lauryl sulfate, sodium olefin sulfonate, cocamidapropyl betaine, alkylbenzene sulfonate, polyoxyethelene alkylphenol sulfate, sodium dodecyl benzene sulfonate, sodium sterate, potassium sterate, potassium myristate, tomadol, polyglyceryl sterate, glycol monosterate, potassium oleate, polyglyceryl oleate, tween, polymers, acrylic polymers, ethyl cellulous, carboxymethyl cellulose, sodium hydroxide, ammonium hydroxide, polyacrylate polymer, polyvinyl pyrolidane, lauric diethanolamine, dimethyldodecylamine oxide, aspartic acid tetrasodium salt, and sodium citrate.. .
Microfluidic glycan analysis
Microfluidic devices and methods for analyzing glycan profiles of glycoproteins are provided. Some embodiments of the devices comprise a deglycosylation column for cleaving glycans, an optional cleaning column for removing proteins, a trapping column for enriching glycans, and a separation column for resolving glycans.
Agilent Technologies, Inc.
Triglyceride production in e. coli
A recombinant e. Coli cell including nucleic acid sequences that encode phosphatidic acid phosphatase (pgp) and diacylglycerol acyltransferase (dgat).
Novel microbial succinic acid producers and purification of succinic acid
The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography..
Natural oil derivative based thickener components used in grease compositions and processes for making such compositions
A grease composition is disclosed, having from 50 to 99 weight percent of a lubricating base oil, from 1 to 30 weight percent of a thickener component including one or more of (i) one or more natural oil derivatives selected from the group consisting of triglycerides, diglycerides, monoglycerides, or oligomers therefrom, fatty acid methyl esters and corresponding fatty acids, salts, and dibasic esters therefrom, and c10-c15 esters, c15-c18 esters, or c+ diesters, or diesters therefrom, (ii) one or more carboxylic acids and/or derivatives thereof, and (iii) one or more of a metal base compound, and from 1 to 15 weight percent of one or more optional additives. Processes for making grease compositions are also disclosed..
Elevance Renewable Sciences, Inc.
Composite phase change material (pcm), manufacturing a composite pcm, and article of clothing including a composite pcm
Composite phase change materials, methods for manufacturing composite phase change materials, and articles of clothing including composite phase change materials for temperature regulation are provided. In one example, a composite phase change material includes a cross-linked polyethylene glycol matrix and a phase change material filler.
Honeywell International Inc.
Disclosed are processes for the preparation of rosin diols accomplished by the reaction of a rosin acid with a glycerine carbonate in the presence of a catalyst, and subsequently where the rosin diol can be reacted with a diacid to generate an amorphous polyester resin.. .
Method of manufacturing non-firing type electrode
A method of manufacturing a non-fired type electrode comprising steps of: (a) applying a conductive paste on a substrate, wherein the conductive paste comprises, (i) 100 parts by weight of a conductive powder, (ii) 0.1 to 8 parts by weight of an inorganic boron compound selected from the group consisting of boron oxide, boric acid, ammonium borate hydrate, borax, potassium tetraborate tetrahydrate and a mixture thereof, wherein the boron component in the inorganic boron compound is 0.05 to 0.6 parts by weight, (iii) 0.1 to 8 parts by weight of an alcohol selected from the group consisting of glycerin, xylose and a mixture thereof, and (iv) an organic vehicle; and (b) heating the applied conductive paste at 100 to 300° c.. .
E I Du Pont De Nemours And Company
Polylactic acid resin composition and resin molded article thereof
Provided are a polylactic acid resin composition excellent in transparency, heat resistance, and migration resistance, and excellent in productivity at the time of the mold forming thereof, and a resin molded article thereof. The polylactic acid resin composition includes a polylactic acid; a reaction product of glycerin, an alkylene oxide mainly formed of ethylene oxide, and a fatty acid having 12 to 24 carbon atoms; and a fatty acid amide having a hydroxyl group..
Dai-ichi Kogyo Seiyaku Co., Ltd.
Method of making a foam
A method of making a foam comprising the following steps. A mixture is created comprising (i) a first reactant comprising triglyceride having acrylate functionality, (ii) a second reactant comprising diacrylate, and (iii) a blowing agent.
Sealed Air Corporation
Method for producing polyalkylene glycol derivative with narrow molecular weight distribution, and acetal group-containing alcohol compound for use therein and alkali metal salt thereof
K represents an integer of 1 to 5.. .
One component isocyanate prepolymer mixture for polyurethane product formulation in a single step process
A one component isocyanate prepolymer mixture for formulating a polyurethane product in a single step process, with monomeric methylene diphenyl diisocyanate (mdi) content in the mixture not exceeding 3%, preferably less than 2%, more preferably less than 1% of the total weight. The mixture contains monofunctional alcohol, an isocyanate component or isocyanate mixture component, propellant, catalyst, stabiliser, and one or more polyols.
Selena Labs Sp. Z O.o.
Preparation super absorbent polymer
The present invention relates to a preparation method of a super absorbent polymer. In the preparation method of the super absorbent polymer according to the present invention, (meth)acrylated polyalkylene glycol is used, thereby preparing a super absorbent polymer having more improved absorbency, water holding capacity and absorbency under pressure while improving dispersibility of a monomer composition containing acrylic acid-based monomers..
Lg Chem, Ltd.
Anti-angptl3 antibodies and uses thereof
A fully human antibody or antigen-binding fragment of a human antibody that specifically binds and inhibits or interferes with at least one activity of human angiopoietin-like protein 3 (hangptl3) is provided. The human anti-hangptl3 antibodies are useful in treating diseases or disorders associated with angptl3, such as hyperlipidemia, hyperlipoproteinemia and dyslipidemia, including hypertriglyceridemia, hypercholesterolemia, chylomicronemia, and so forth.
Regeneron Pharmaceuticals, Inc.
Compositions comprising enzyme-cleavable oxycodone prodrug
The embodiments provide compound kc-8, n-1-[3-(oxycodone-6-enol-carbonyl-methyl-amino)-2,2-dimethyl-propylamine]-arginine-glycine-malonic acid, or acceptable salts, solvates, and hydrates thereof. The present disclosure also provides compositions, and their methods of use, where the compositions comprise a prodrug, compound kc-8, that provides controlled release of oxycodone.
Signature Therapeutics, Inc.
Antisense-induced exon2 inclusion in acid alpha-glucosidase
The present disclosure relates to antisense oligomers and related compositions and methods for inducing exon inclusion as a treatment for glycogen storage disease type ii (gsd-ii) (also known as pompe disease, glycogenosis ii, acid maltase deficiency (amd), acid alpha-glucosidase deficiency, and lysosomal alpha-glucosidase deficiency), and more specifically relates to inducing inclusion of exon 2 and thereby restoring levels of enzymatically active acid alpha-glucosidase (gaa) protein encoded by the gaa gene.. .
Useful thiophene derivatives in the treatment of diabetes
Or an enantiomer, diastereoisomer, hydrate, solvate, tautomer, racemic mixture or pharmaceutically acceptable salt thereof or to its use as a drug in particular intended for treating and/or preventing diabetes, its complications and/or associated pathologies, advantageously diabetes of type ii and hyperglycemia.. .
Novel benzimidazole tetrahydropyran derivatives
Novel compounds described herein are activators of amp-protein kinase and may be useful in the treatment, prevention and suppression of diseases mediated by the ampkactivated protein kinase. The compounds of the present invention may be useful in the treatment of type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, hypercholesterolemia, and hypertension..
Merck Sharp & Dohme Corp. A Corporation, A Subsidiary Of Merck & Co., Inc.
Crystalline polymorphic forms of an antidiabetic compound
This compound is useful as a glucagon receptor antagonist and serves as a pharmaceutically active ingredient for the treatment of type 2 diabetes and related conditions, such as hyperglycemia, obesity, dyslipidemia, and the metabolic syndrome. Hydrates, hemihydrates, anhydrates and similar polymorphic forms are included..
Method for producing polyalkylene glycol derivative having amino group at end, with narrow molecular weight distribution
4) a step of reducing a compound of the general formula (5) to obtain a compound of the general formula (1).. .
Tri-salt form of metformin
Provided herein are tri-salt compounds comprising a compound having two acidic functional groups and one basic functional groups (e.g., aspartate or glutamate), metformin, and polyunsaturated fatty acids, such as eicosapentaenoate or docosahexaenoate. The salts can be used in the treatment of diabetes, diabetes with concomitant dyslipidemia (e.g., high triglycerides) and diabetes exacerbated cardiovascular complications, such as cardiac arrhythmia, cardiac ischemia, myocardial infarction, cardiomyopathy, and stroke.
Thetis Pharmaceuticals Llc
Process of crude glycerin purification originated from transesterifications with alkaline catalysis without using acidification and distillation producing purified glycerin 96% and 99% purity
A process of crude glycerin purification originated from transesterification with alkaline catalysis without using acidification and distillation producing purified glycerin 96% and 99% purity, wherein the purification technique of glycerin obtained from productions of fatty esters using the alkaline catalysis.. .
Glycerosolution Química Ltda.
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Gly topics: Door Assembly, Swimming Goggles, Transverse, Alkoxylate, Fluoropolymer, Air Cleaning, Rotor Shaft, Aspect Ratio, Disconnect, Synchronization, Remote Control, Ethylene Glycol, Surfactant, Combustion, Steviol Glycosides
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