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Gly

Gly-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Controlling the architecture, coordination, and reactivity of nanoparticle coating utilizing an amino acid central scaffold
The Florida State University Research Foundation, Inc.
June 15, 2017 - N°20170168042

A series of multicoordinating and multifunctional ligands optimized for the surface-functionalization of luminescent quantum dots (qds) and gold nanoparticles (aunps) alike is disclosed. An l-aspartic acid precursor is modified with functionality, through simple peptide coupling chemistry, one or two lipoic acid (la) groups and poly(ethylene glycol) (peg) moieties in the same ligand. These ligands were combined with a new ...
Ion exchange resin and method for adsorbing and separating metal
Sumitomo Metal Mining Co., Ltd.
June 15, 2017 - N°20170166995

Provided is a system for efficiently recovering trace metal from a large amount of a raw material, such as when trace metal is recovered from nickel oxide ore. This ion exchange resin has, on a carrier, an amide derivative represented by the following general formula. In the formula, r1 and r2 represent the same or different alkyl groups, r3 represents ...
Methods for producing and using in vivo pseudotyped retroviruses
University Of Iowa Research Foundation
June 15, 2017 - N°20170166924

The present invention provides novel pseudotyped retroviral vectors that can transduce human and other cells. Vectors are provided that are packaged efficiently in packaging cells and cell lines to generate high titer recombinant virus stocks expressing novel envelope glycoproteins. The present invention further relates to compositions for gene therapy.
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Refrigerator oil composition, and refrigeration device
Idemitsu Kosan Co., Ltd.
June 15, 2017 - N°20170166831

Provided is a refrigerator oil composition for a refrigerant containing an unsaturated fluorinated compound having a carbon-carbon unsaturated bond, which is represented by a general formula (i): c2fpr4-p, wherein r each independently represents a hydrogen atom, a chlorine atom, a bromine atom, or an iodine atom, and p represents an integer of 1 to 3. The composition contains a base ...
Compositions and methods for reducing air entrainment in well cement slurries
Schlumberger Technology Corporation
June 15, 2017 - N°20170166800

Well cementing compositions include an aqueous fluid, portland cement and an air entrainment suppressing agent. The air entrainment suppressing agent includes a blend of a silicone and polypropylene glycol, or a silicone that is functionalized with ether groups. Methods for preparing well cementing compositions comprise adding the air entrainment suppressing agent to the aqueous fluid, and combining the mixing fluid ...
Laminating adhesives based on primary hydroxyl-containing curatives
Henkel Ip & Holding Gmbh
June 15, 2017 - N°20170166790

A curative containing two or more primary hydroxyl groups per molecule and one or more moieties derived from a secondary hydroxyl-containing polyol such as polypropylene glycol is prepared in a multistage process wherein the secondary hydroxyl-containing polyol is end-capped with an excess of a reactant such as a polybasic acid and the resulting functionalized intermediate is then reacted with a ...
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Oxidatively drying polyurethane dispersions with particularly high chemical resistance
Covestro Deutschland Ag
June 15, 2017 - N°20170166685

The present invention relates to hydrophilized polyurethanes having a particularly high content of hydroxy-functional, unsaturated triglycerides, to a process for preparing polyurethane dispersions based thereon, to the use of the dispersions as binders in oxidatively drying coating materials having particularly high chemical resistance, and to articles and substrates coated with these coating materials.
Polyurethane materials formed from unsaturated plant oils via an alkyne zipper reaction
International Business Machines Corporation
June 15, 2017 - N°20170166680

A process of forming a polyurethane material includes forming an alkyne-terminated triglyceride material from an unsaturated plant oil. The process also includes forming a hydroxyl-terminated polyol material from the alkyne-terminated triglyceride material. The process further includes polymerizing a mixture that includes the hydroxyl-terminated polyol material to form a polyurethane material.
Chimeric antigen receptors recognizing cancer-specific tn glycopeptide variants
The University Of Chicago
June 15, 2017 - N°20170166652

Disclosed are binding proteins, or fragments thereof, that specifically binds to a cancer-specific glycosylation variant of a protein and to a second epitope on the same protein, to a different protein presented on the same cell, or to a different protein presented on a different cell, such as an encoded polypeptide binding to both a cancer cell and an activated ...
Antibody variants composition
Kyowa Hakko Kirin Co., Ltd.
June 15, 2017 - N°20170166650

Among n-glycoside-linked sugar chains which are bound to the fc region of an antibody, sugar chains which are bound to asn at position 297 relates to the activity and stability of the antibody in blood, but there is a possibility that extra sugar chains bound to the amino acid residues at positions other than 297 have influences upon the antibody constant region-mediated ...
Aldehyde-tagged immunoglobulin polypeptides and methods of use thereof
Redwood Bioscience, Inc.
June 15, 2017 - N°20170166639

The present disclosure provides aldehyde-tagged immunoglobulin (ig) polypeptides that can be converted by a formylglycine-generating enzyme to produce a 2-formylglycine (fgly)-modified ig polypeptide. An fgly-modified ig polypeptide can be covalently and site-specifically bound to a moiety of interest to provide an ig conjugate. The disclosure also encompasses methods of production of such aldehyde-tagged ig polypeptides, fgly-modified ig polypeptides, and ...
Antidiabetic substituted heteroaryl compounds
Merck Sharp & Dohme Corp.
June 15, 2017 - N°20170166578

The present invention relates to a compound represented by formula (i): and pharmaceutically acceptable salts thereof. The compounds of formula i are agonists of g-protein coupled receptor 40 (gpr40) and may be useful in the treatment, prevention and suppression of diseases mediated by the g-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of type 2 diabetes ...
Method for the production of bio-sourced acrylic acid
Arkema France
June 15, 2017 - N°20170166507

The present invention relates to the manufacture of biobased acrylic acid from glycerol as starting material, the term “biobased acid” indicating that the acrylic acid is essentially based on a carbon source of natural origin.
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Method of manufacturing an implantable film and prothesis comprising such a film
Sofradim Production
June 15, 2017 - N°20170165399

A method for manufacturing an implantable film and a prosthesis comprising such a film the present invention relates to a method for manufacturing a non porous film intended to be implanted in the human body, said method comprising the following steps: preparation of a first film, called intermediate film, via gelling of a starting solution comprising at least one polymer ...
Compositions, delivery systems and refills for emitting two or more compositions
S. C. Johnson & Son, Inc.
June 15, 2017 - N°20170165391

A system for delivering a multi-phase fragrance composition comprises a container having a body forming a reservoir and an opening in communication with the reservoir and a multi-phase composition disposed within the reservoir. The multi-phase composition comprises a water phase composition and an oil phase composition and the water phase composition and the oil phase composition are substantially separated. The ...
Method for treating retinal conditions using an intraocular tamponade
Santen Sas
June 15, 2017 - N°20170165368

Composition comprising at least one fatty acid glycerol ester for use during or after a vitrectomy procedure, said composition being bioresorbable, being injectable in the vitreous cavity, having a density below 1, more preferably comprised between 0. 90 and 1, or a density above 1 more preferably between 1 and 1. 5; having a surface tension of less than 50 dynes/cm more preferably ranging from 20 and 30 dynes/cm, ...
Filovirus consensus antigens, nucleic acid constructs and vaccines made therefrom, and methods of using same
The Trustees Of The University Of Pennsylvania
June 15, 2017 - N°20170165350

Nucleic acid molecules and compositions comprising one or more nucleic acid sequences that encode a consensus filovirus immunogen including a consensus marburgvirus filovirus glycoprotein marv gp immunogen, a consensus ebolavirus sudan filovirus glycoprotein sebov gp immunogen and a consensus ebolavirus zaire glycoprotein zebov gp immunogen are disclosed. The coding sequences optionally include operable linked coding sequence that encode a signal ...
Recombinant subunit west nile virus vaccine for protection of human subjects
Hawaii Biotech, Inc.
June 15, 2017 - N°20170165349

A west nile virus vaccine for human use is described that preferably contains a recombinantly produced form of truncated west nile virus envelope glycoprotein and aluminum adjuvant. The vaccine is acceptable for use in the general population, including immunosuppressed, immunocompromised, and immunosenescent individuals. The vaccine is safe and effective for use in all healthy and at-risk populations. A pharmaceutically acceptable ...
Compositions and methods for inducing immune tolerance
The Scripps Research Institute
June 15, 2017 - N°20170165333

The present invention provides liposomal compositions for inducing immune tolerance. The compounds typically comprise a liposome displaying a specific antigen and also a binding moiety for a sialic acid binding ig-like lectin (siglec) expressed on b cells. The invention also provides methods for inducing tolerance to a protein or polypeptide antigen (e. G., a protein antigen) in a subject. The ...
Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of asgpr
Pfizer Inc.
June 15, 2017 - N°20170165284

Compounds of formula (a) are described herein and the uses thereof for the treatment of diseases, conditions and/or disorders mediated by pharmaceutical compositions and the uses thereof as asialoglycoprotein receptor (asgpr) targeting agents.
Heteroaromatic compounds and their use as dopamine d1 ligands
Pfizer Inc.
June 15, 2017 - N°20170165270

And pharmaceutically acceptable salts thereof and n-oxides thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds (n-oxides thereof or or pharmaceutically acceptable salts of the compound or the n-oxides) and the uses of such compounds (n-oxides thereof or or pharmaceutically acceptable salts of the compound or the n-oxides) for the treatment of ...
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