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This page is updated frequently with new Gly-related patent applications.




Date/App# patent app List of recent Gly-related patents
04/07/16
20160097086 
 Compositions and methods for rt-pcr patent thumbnailCompositions and methods for rt-pcr
The present invention relates to compositions and methods having propylene glycol and dna polymerase for facilitating the rapid and efficient amplification of nucleic acid molecules and the detection and quantitation of rna molecules, and for increasing the detection sensitivity and reliability through generation of secure cdna molecules prior to gene-specific primer dependent amplification. The reagent mixture comprises a ready to use reagent solution, wherein the solution comprises: (a) propylene glycol in a concentration between about 20% and about 50%; (b) a viral reverse transcriptase; and (c) at least one dna polymerases, in a buffer suitable for use in a reverse transcription reaction, wherein the buffer comprises a co-factor metal ion and nucleoside triphosphates..

04/07/16
20160097085 
 Compositions and methods for cdna synthesis patent thumbnailCompositions and methods for cdna synthesis
The methods and compositions for preparing cdnas, and more particularly, compositions having propylene glycol for synthesizing a cdna molecule or molecules from an mrna template or population of mrna templates under conditions sufficient to increase the detection sensitivity and cdna yield and to simplify and improve the reliability of reverse transcription are provided. The reagent mixture comprises a ready to use reagent solution, wherein the solution comprises: (a) propylene glycol in a concentration between about 25% and about 50%; and (b) a viral reverse transcriptase selected from the group consisting of amv rt, rsv rt, mmlv rt, hiv rt, eiav rt, rav2 rt, aslv rt, rnaseh (−) rt, superscript ii rt, and thermoscript rt, in a buffer suitable for use in a reverse transcription reaction, wherein the buffer further comprises a co-factor metal ion and nucleoside triphosphates..

04/07/16
20160097074 
 Defined glycoprotein products and related methods patent thumbnailDefined glycoprotein products and related methods
The invention provides methods, databases and systems for making glycoprotein products having defined properties.. .
Momenta Pharmaceuticals, Inc.


04/07/16
20160097072 
 Non-caloric sweeteners and methods for synthesizing patent thumbnailNon-caloric sweeteners and methods for synthesizing
Disclosed are steviol glycosides referred to as rebaudioside v and rebaudioside w. Also disclosed are methods for producing rebaudioside m (reb m), rebaudioside g (reb g), rebaudioside ka (reb ka), rebaudioside v (reb v) and rebaudioside (reb w)..
Conagen Inc.


04/07/16
20160097071 
 Non-caloric sweeteners and methods for synthesizing patent thumbnailNon-caloric sweeteners and methods for synthesizing
Disclosed are steviol glycosides referred to as rebaudioside v and rebaudioside w. Also disclosed are methods for producing rebaudioside m (reb m), rebausoside g (reb g), rebaudioside ka (reb ka), rebaudioside v (reb v) and rebaudioside (reb w)..
Conagen Inc.


04/07/16
20160097070 
 Non-caloric sweeteners and methods for synthesizing patent thumbnailNon-caloric sweeteners and methods for synthesizing
Disclosed are steviol glycosides referred to as rebaudioside v and rebaudioside w. Also disclosed are methods for producing rebaudioside m (reb m), rebausoside g (reb g), rebaudioside ka (reb ka), rebaudioside v (reb v) and rebaudioside (reb w)..
Conagen Inc.


04/07/16
20160097044 
 Antimicrobial enzyme fusions reduce resistance and kill intracellular staphylococcus aureus patent thumbnailAntimicrobial enzyme fusions reduce resistance and kill intracellular staphylococcus aureus
Multi-drug resistant bacteria are a persistent problem in modern health care, food safety and animal health. There is a need for new antimicrobials to replace over-used conventional antibiotics.
The United States Of America, As Represented By The Secretary Of Agriculture


04/07/16
20160097020 
 Aqueous solutions containing a complexing agent in high concentration patent thumbnailAqueous solutions containing a complexing agent in high concentration
Aqueous solution comprising (a) in the range of from 30 to 60% by weight of a complexing agent, selected from the alkali metal salts of methylglycine diacetic acid and the alkali metal salts of glutamic acid diacetic acid, (b) in the range of from 700 ppm to 7% by weight of a polymer being selected from polyamines, the n atoms being partially or fully substituted with ch2cooh groups, partially or fully neutralized with alkali metal cations, ppm and percentages referring to the total respective aqueous solution. .
Basf Se


04/07/16
20160097019 
 Wax compositions and the effect of metals on burn rates patent thumbnailWax compositions and the effect of metals on burn rates
A wax composition is disclosed, comprising a hydrogenated natural oil with (i) at least about 50 wt % of a triacylglycerol component having a fatty acid composition from about 14 to about 25 wt % c16:0 fatty acid, about 45 to about 60 wt % c18:1 fatty acid and about 20 to about 30 wt % c18:0 fatty acid, (ii) a nickel content of less than 1 ppm, and (iii) a melt point of about 49° c. To about 57° c.
Elevance Renewable Sciences, Inc.


04/07/16
20160096951 
 New carbodiimides having terminal urea and/or urethane groups, methods for producing said carbodiimides, and use of said carbodiimides patent thumbnailNew carbodiimides having terminal urea and/or urethane groups, methods for producing said carbodiimides, and use of said carbodiimides
The invention relates to novel carbodiimides having terminal urea and/or urethane groups, methods for the preparation thereof and use thereof as stabilizers in ester-based polyols, in polyethylene terephthalate (pet), in polybutylene terephthalate (pet), in polytrimethylene terephthalate (ptt), in copolyesters, in thermoplastic polyester elastomers (tpe e), in ethylene vinyl acetate (eva), in polylactic acid (pla) and/or in pla derivatives, in polybutylene adipate terephthalates (pbat), in polybutylene succinates (pbs), in polyhydroxyalkanoates (pha), in blends, in triglycerides, in thermoplastic polyurethanes, in polyurethane elastomers, in pu adhesives, in pu casting resins, for pu coatings or in pu foams.. .
Rhein Chemie Rheinau Gmbh


04/07/16
20160096789 

Process for the preparation of monoethylene glycol


The invention provides a process for the preparation of monoethylene glycol from sucrose comprising the steps of: i) hydrolysing sucrose to form a reaction product stream comprising glucose and fructose; ii) separating the reaction product stream comprising glucose and fructose into a fructose or fructose derivative rich stream and a glucose rich stream; and iii) contacting the glucose rich stream with hydrogen in a reactor in the presence of a solvent and a catalyst system with catalytic hydrogenation abilities to produce a product stream comprising monoethylene glycol.. .
Shell Oil Company


04/07/16
20160096157 

Apparatus for the controlled mixing and dispensing of liquids


A new apparatus & method of use thereof for providing a selectable e-liquid juice solution from a dispenser are provided. In one embodiment a method for (a) providing a user determined combination of various liquids in a predetermined mixture that results in customized e-liquid juice having user specified quantities of propylene glycol, vegetable glycerin, nicotine, and flavoring is disclosed; (b) separately storing at least four liquids to be mixed after user determined selections are input; (c) facilitating the storage in memory of recipes for e-liquid juice or combinations thereof; (d) receiving a selection or user input for a specific combination of liquids; (e) dispensing automatically in response to the selection or user input the resulting volume of liquid combination..

04/07/16
20160095955 

Pliable medical device and use


A firm but pliable medical device for use as a bone graft substitute or bone graft extender retains its shape without the requirement of a containment device, such as a syringe. Because the device is solid, it is easy to locate or position in-vivo and, in the moist environment of the body, it will hold its shape well, for an extended time.
Cerapedics, Inc.


04/07/16
20160095934 

Dasatinib and nonlinear configuration polyethylene glycol conjugate


A dasatinib and nonlinear configuration polyethylene glycol conjugate represented by formula i, wherein core is the core structure of a nonlinear configuration of polyethylene glycol, selected from a residue of pentaerythritol, methylglucoside, sucrose, diethylene glycol, propanediol, glycerol or polyglycerol removaed the hydrogen atom from the hydroxyl group; p is a polyethylene glycol residue with a number-average molecular weight of 300-60000 da; x is selected from single bond, —ch2co—, —ch2ch2oco— or ch2ch2nhco—; and i is selected from 3, 4, 6 or 8.. .
Jenkem Technology Co., Ltd.(tianjin)


04/07/16
20160095835 

Compositions containing omega-3 oil and uses thereof


The invention provides pharmaceutical compositions containing omega-3 oil and a non-hydrophilic co-solvent that have an increased absorption rate. The pharmaceutical compositions may further contain one or more pharmaceutical organic molecules.
Maine Natural Health Company, Inc.


04/07/16
20160095823 

Methods of using propofol derivatives for analgesia


The present invention concerns compounds derived from the anaesthetic propofol that are useful as analgesics and methods of using the same. The compounds act as co-activators of strychnine-sensitive glycine receptors and may have greater activity at those glycine receptors than at gabaa..
Medizinische Hochschule Hannover


04/07/16
20160095800 

Polyurethane elastomer dental appliance


A dental jacket made of a hard, solvent free, substantially non-hydrophilic polyurethane elastomer. The jacket elastomer has a hardness of not less than about shore d65.

04/07/16
20160095799 

Method for making a machinable block of polyurethane elastomer for use in fabricating dental appliances


A method of making a machinable puck of a hard, solvent free, substantially non-hydrophilic polyurethane elastomer for use in fabricating dental appliances. The elastomer has a hardness of not less than about shore d65.

04/07/16
20160095676 

Polyurethane elastomer composition for use in making dental appliances


A hard, solvent free, substantially non-hydrophilic polyurethane elastomer for use in making dental appliances. The elastomer has a hardness of not less than about shore d65.

04/07/16
20160095338 

Non-caloric sweeteners and methods for synthesizing


Disclosed are steviol glycosides referred to as rebaudioside v and rebaudioside w. Also disclosed are methods for producing rebaudioside m (reb m), rebausoside g (reb g), rebaudioside ka (reb ka), rebaudioside v (reb v) and rebaudioside (reb w)..
Conagen Inc.


04/07/16
20160095318 

Antimicrobial composition


An antimicrobial composition includes benzalkonium chloride in an amount of 0.06% w/w to 0.19% w/w and cocamidopropyl pg-dimonium chloride phosphate in an amount of 0.6% w/w to 1.9% w/w. The composition also includes propylene glycol in an amount of 0.4% w/w to 1.2% w/w and triethylene glycol in an amount of 0.1% w/w to 0.3% w/w.
Safehands Solutions, Llc


04/07/16
20160095317 

N-phosphonomethylglycine guanidine derivative salts


The present invention provides guanidine compounds and salts thereof that may be useful, for example, in the preparation of herbicidal compositions. The compounds may be used, for example, to prepare n-phosphonomethylglycine guanidine salts having improved herbicidal efficacy over glyphosate alone..
Flamel Technologies


04/07/16
20160095312 

Cleanser compositions and methods for using the same


The present invention is directed to anti-microbial cleanser compositions comprising linalool, hinokitiol and dipropylene glycol. The present invention further provides methods for using these compositions to maintain eyelid hygiene, to treat an ocular disorder or to clean a skin surface.
Advanced Vision Research, Inc.


03/31/16
20160091512 

Ellagic acid formulations for use in coagulation assays


The present invention relates to ellagic acid formulations for performing coagulation assays that are highly stable for long term storage and reduce assay time. Particularly, aspects of the present invention are directed to a composition and method of preparing ellagic acid in a highly soluble format for use in a coagulation assay.
Abbott Point Of Care Inc.


03/31/16
20160091502 

Fibrosis biomarker assay


Methods of diagnosis or of quantitation of fibrosis are provided that comprise conducting an immunoassay to measure neo-epitope containing protein fragments naturally present in a biofluid sample, and associating an elevation of the measure in the patient above a normal level with the presence or extent of fibrosis. The immunoassay is conducted by a contacting protein fragments naturally present in the sample with an immunological binding partner reactive with a neo-epitope formed by cleavage of a protein by a proteinase and measuring the extent of binding of peptide fragments to the immunological binding partner to measure therein protein fragments comprising the neo-epitope.
Nordic Bioscience A/s


03/31/16
20160091401 

Gram staining method with improved decolorization of the crystal violet-iodine complex from gram negative bacteria


Provided herein are methods of staining biological material for the purpose of detecting, and in some examples also identifying, microorganisms. Methods of gram staining bacteria using a slow-acting decolorizing formulation, such as one that includes 1,2-propandiol or ethylene glycol, can be used to extend the time of the decolorizing step, and thus permit automation of the gram staining method.
Ventana Medical Systems, Inc.


03/31/16
20160090577 

Heterologous expression of glycine n-acyltransferase proteins


The present disclosure provides novel compositions and methods for the production and use of polynucleotide sequences encoding a glycine n-acyltransferase protein (glyat, glyatl 1, glyatl 2, and glyatl 3) for the biosynthesis of n-acylglycine biosurfactants within a heterologous expression system.. .
Dow Agrosciences Llc


03/31/16
20160090565 

Cleaning composition and semiconductor device fabrication


Provided is a cleaning composition and its applications. The cleaning composition comprises a mixture of a halogen-containing compound and an organic solvent.
Taiwan Semiconductor Manufacturing Company, Ltd.


03/31/16
20160090444 

Drug loading pentablock polymers


Novel pentablock polymers having a pcl-pla-peg-pla-pcl or pcl-pga-peg-pga-pcl configuration, wherein peg is polyethylene glycol, pcl is poly(8-caprolactone), pga is poly(glycolic acid), and pla is poly(lactic acid), and methods of making nanoparticles from the pentablock polymers, are disclosed. The invention is also directed to a method for preparing nanoparticle compositions comprised of polymers with high levels of bioactive or diagnostic agents..
The Curators Of The University Of Missouri


03/31/16
20160090443 

Biodegradable polyester resin and article containing the same


Provided are a biodegradable polyester resin and an article including the resin. The provided biodegradable polyester resin includes an aliphatic dicarboxylic acid residue including a succinic acid residue and an adipic acid residue; and an aliphatic diol residue including at least one selected from the group consisting of an ethylene glycol residue and a butanediol residue in order to improve biodegradability and flexibility..
Samsung Fine Chemicals Co., Ltd.


03/31/16
20160090410 

Fucosylation-deficient cells


An isolated nucleic acid encoding an fx protein having a serine at position 79, a lysine at position 90, a leucine at position 136, an arginine at position 211, a serine at position 289, and a combination thereof is provided. Cells having a gene encoding a modified fx protein are provided, wherein the cells exhibit a reduced ability to fucosylate a glycoprotein at a first temperature, but exhibit the ability to fucosylate the glycoprotein at a second temperature.
Regeneron Pharmaceuticals, Inc.


03/31/16
20160090409 

Methods for the treatment of neurodegeneration


The invention encompasses the discovery that fc-containing polypeptides that include branched glycans and that are sialylated on the branched glycan (e.g., on an α 1,3 and/or α 1,6 arm in the fc region's n-linked glycosylation site), with, e.g., a neuac-α 2,6-gal or neuac-α 2,3-gal terminal linkage, are useful in treating neurodegeneration, e.g., in the treatment of neurodegenerative diseases such as alzheimer's disease. The present disclosure provides, in part, methods for treating neurodegeneration or neurodegenerative diseases by administering compositions containing such fc-containing polypeptides as well as methods for evaluating, identifying, and/or producing (e.g., manufacturing) such polypeptides for the treatment of neurodegeneration..
Momenta Pharmaceuticals, Inc.


03/31/16
20160090375 

Substituted phenylazole derivative


Compounds are provided having an excellent hypoglycemic effect and β cell- or pancreas-protecting effects, or pharmaceutically acceptable salts thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause hyperglycemia due to abnormal glucose metabolism. A compound represented by general formula (i), or a pharmaceutically acceptable salt thereof, is disclosed..
Daiichi Sankyo Company, Limited


03/31/16
20160089921 

Thermal transfer sheet


The above object can be achieved by providing a thermal transfer sheet 10 in which one or both of a color material layer 3 and a protective layer 4 is provided on one surface of a substrate 1, and a back face layer 5 is provided on another one surface of the substrate 1, the thermal transfer sheet being characterized in that the back face layer 5 is contained with (i) a cured acrylic polyol resin in which an acrylic polyol resin is cured by a curing agent, and (ii) a glycerin fatty acid ester or a polyglycerin fatty acid ester.. .

03/31/16
20160089471 

Sheet for cutaneous application containing vitamin e or an ester thereof


Sheet for cutaneous application comprising a support layer made of loosely woven fabric embedded in a layer of silicone elastomer incorporating vitamin e or an ester thereof, wherein the layer of silicone elastomer has a thickness less than or equal to 2.0 mm and the silicone elastomer contains an elasticity modifier consisting of a triglyceride of saturated c8-c18 fatty acids.. .
Boi.lo.ga. S.r.l.


03/31/16
20160089441 

Composition for the treatment of cold sores


A composition used in the treatment of the cold sores is composed of water, propylene glycol, mineral oil, behenyl alcohol or docosanol, benzocaine, vitamin e tocopheryl, sucrose stearate, and benzyl alcohol.. .
Oralabs, Inc.


03/31/16
20160089437 

Flocculated megestrol acetate suspension


The present invention relates to a novel oral pharmaceutical composition in the form of a stable flocculated suspension in water, said composition comprising micronized megestrol acetate at a concentration of 10 to 200 mg per ml, polysorbate at a concentration of 0.01% to 12.6% weight by volume, or polyethylene glycol at a concentration of about 0.01% to 5.0% weight by volume, polyoxyl 35 castor oil at a concentration of 0.05% to 51.5% weight by volume and/or polyoxyl 40 hydrogenated castor oil at a concentration of 0.05% to 45% weight by volume in a stable flocculated suspension in water. The composition also may include preservatives, sweeteners, ph adjusting agents and flavoring agents..

03/31/16
20160089391 

Molecular targets for cardiovascular disease


The invention relates to methods and compositions for treating and preventing cardiovascular disease, including but not limited to treating and preventing endothelial dysfunction in subjects having hyperhomocysteinemia, hyperglycemia, or a combination of hyperhomocysteinemia and hyperglycemia. As endothelial dysfunction is an indicator for atherosclerosis and cardiovascular disease, this treatment has general impact for early prevention and treatment for all cardiovascular disease.
Temple University-of The Commonwealth System Of Higher Education


03/31/16
20160089333 

[0001] foam-forming compositions and methods for delivering an active to a body cavity


Provided is a foam-forming formulation and method of treating an infection in a body cavity. The foam-forming formulation contains hydrogen peroxide, monoglyceride crystals, at least one acid and/or buffer which is present in an amount to provide a ph of 3 to 5 within a body cavity, a blowing agent in an amount to blow the foam-forming composition and form a foam, and water.
Zelmic Ab


03/31/16
20160089312 

Cosmetic composition containing an oily phase comprising a silicone elastomer in dispersed aqueous droplets and a particular surfactant


The invention relates to a cosmetic composition comprising at least an oily phase, the said oily phase comprising at least: (i) a silicone elastomer present in aqueous droplets which are dispersed in said oily phase, (ii) at least one particular surfactant chosen from: —a) silicone surfactants having a chemical structure comprising silicone side chains and hydrophilic side chains, of which the general formula (i) is: (i) —b) silicone surfactants having a chemical structure comprising hydrophilic chains at both ends (α- ωsubstitution) of the main chain, of general formula (ii) below: (ii) —c) hydrocarbon-based surfactants resulting from the esterification of a mixture of polyglycerol with (i) a polyhydroxystearic acid, with 2 to 5 polyglycerol units, (ii) linear or branched aliphatic dicarboxylic acids containing 4 to 14 carbon atoms, and (iii) saturated or unsaturated, linear or branched fatty acids containing from 16 to 20 carbon atoms.. .
L'oreal


03/31/16
20160088865 

Sweetener composition including enzymatically processed stevia and manufacturing


A low-calorie sweetener composition, and method of manufacturing the same. The method includes providing a first sweetener having a mean particle size of between 100-350 μm in diameter and coating the first sweetener with a second sweetener.
Eco Sweeteners, Llc


03/24/16
20160084844 

Methods of identifying glycopeptides recognized by disease-associated auto-antibodies


Methods for identifying glycopeptides and more particularly glycopeptide epitopes that are specifically recognized by disease-associated auto-antibodies are provided. In some aspects the auto-antibodies are cancer-associated or autoimmune disease associated.
Glycozym, Inc.


03/24/16
20160083758 

Acyl-acp thioesterases and mutants thereof


Novel plant acyl-acp thioesterase genes of the fatb and fata classes and proteins encoded by these genes are disclosed. The genes are useful for constructing recombinant host cells having altered fatty acid profiles.
Solazyme, Inc.


03/24/16
20160083741 

Increasing the content of long chain fatty acids in seed oil


Provided are plants that express, or overexpress, a pplaiiiδ protein. Constitutive or seed-specific expression of pplaiiiδ protein in arabidopsis increases seed oil content, the amount of c20 and c22 fatty acids, and the amount of c56, c58, and c60 triacylglycerols, effectively resulting in significantly higher oil yield per plant.
The Curators Of The University Of Missouri


03/24/16
20160083725 

Prophylactic and/or therapeutic agent for inflammatory disease, and screening prophylactic and/or therapeutic drug for inflammatory disease


A prophylactic and/or therapeutic agent for an inflammatory disease that comprises a substance capable of inhibiting the expression or function of leucine rich alpha 2 glycoprotein (lrg). A method of screening for an anti-inflammatory substance using lrg or an lrg-expressing cell, wherein the inhibition of the expression or function of lrg is used as an index..

03/24/16
20160083713 

Novel peptidyl alpha-hydroxyglycine alpha-amidating lyases


The present patent application concerns an enzyme capable of catalysing the conversion of a α-hydroxyglycine to an α-amide and the use of such enzymes for producing a c-terminal α-amidated peptide.. .
Novo Nordisk A/s


03/24/16
20160083672 

Lubricating oil composition for refrigerators


Provided is a lubricating oil composition for a refrigerator which uses a base oil including as the main component at least one kind of oxygen-containing compounds selected from polyoxyalkylene glycols, polyvinyl ethers, copolymers of poly(oxy)alkylene glycols or monoethers thereof and polyvinyl ethers, polyol esters, and polycarbonates. The lubricating oil composition for a refrigerator is used for a refrigerator that uses, as a refrigerant, a fluorine-containing organic compound, which is a refrigerant applicable to current car air conditioner systems or the like and has a specific polar structure, and has favorable sealing property, a low coefficient of friction factor in a sliding part, and excellent stability as well as excellent compatibility with the refrigerant..
Idemitsu Kosan Co., Ltd.


03/24/16
20160083671 

Polyalkylene glycol-based industrial lubricant compositions


A lubricant composition comprises as a lubricant base, an oil soluble polyalkylene glycol suitable for use as a lubricant in an industrial oil, grease or metal working fluid; and an additive comprising (1) alkylated phenyl-α-naphthylamine; and (2) 2,2,4-trialkyl-1,2-dihydroquinoline.. .
Vanderbilt Chemical, Llc


03/24/16
20160083610 

Bondable blood-friendly polymer and preparing method thereof


A bondable blood-friendly polymer is a terpolymer or a quadripolymer at least formed by polyethylene glycol alkyl ether acrylate or polyethylene glycol alkyl ether methacrylate (i), and zwitterionic acrylic ester or zwitterionic methacrylic ester (ii), and acrylic acid or a methacrylate derivative with an epoxypropyl group, an isocyanate group, a trialkoxy silane, a hydroxyalkyl group, a propargyl group or a quaternary ammonium group (iii). In the present invention, the blood-friendly polymer with a potentially-bondable group has the following advantages: although the water insolubility thereof is implemented by using the hydrophobicity physical effect of an existing higher alkyl acrylate linkage, the blood friendliness of a coating is reduced due to the existence of a great number of hydrophobic chain links in the polymer; and a physical coating is slowly desolventized from the surface to be ablated in the application process of the physical coating.
G Y Bio-materials Co., Ltd.


03/24/16
20160083598 

White ink


An ink comprising: (a) from 1 to 25 parts of surface treated titanium dioxide; (b) from 8 to 25 parts of a first solvent selected from the group consisting of ethylene glycol, diethylene glycol, triethylene glycol and dipropylene glycol; (c) from 2 to 12 parts of a second solvent selected from the group consisting of 2-pyrrolidone, n-methyl-2-pyrrolidone, n-ethyl-2-pyrrolidone, n-cyclohexyl-2-pyrrolidone and n,n-dimethylacetamide; (d) from 15 to 45 parts of glycerol; (e) from 0.1 to 2 parts of an acetylenic surfactant; (f) from 0.001 to 2 parts of 1,2-benzisothiazolin-3-one; (g) from 0 to 20 parts of polymer particles; and (h) the balance to 100 parts water.. .
Fujifilm Imaging Colorants, Inc.


03/24/16
20160083573 

Transparent and antistatic pmma composition


A transparent antistatic composition based on polymethyl methacrylate (pmma), including: 55% to 99.9% by weight of pmma, and 0.1% to 45% by weight of at least one polyamide (pa) block-containing and polyether (pe) block-containing copolymer (peba) including polyethylene glycol (peg), with respect to the total composition weight, said copolymer including in the range 50% to 80% by weight of peg with respect to the total weight of copolymer. Also, the use of a composition of this type for the manufacture of at least a portion of the following items: an industrial part, an automobile part, a safety accessory, sign, luminous strip, signalling and advertizing panel, display, etching, furniture, shop fitting, decoration, contact ball, dental prosthesis, ophthalmological implant, membrane for hemodialysis, optic fibers, artwork, sculpture, camera lenses, disposable camera lenses, printing support, in particular a support for direct printing with uv inks for pictures, photographs, window glass, panoramic roof..
Arkema France


03/24/16
20160083550 

Method of recycling vulcanized rubber


A method for recycling vulcanized rubber provided the use of a reactor and a glycerol and hydrochloric acid solution. A quantity of vulcanized rubber is reduced in size, and submerged into a reactor containing the glycerol and hydrochloric acid solution.

03/24/16
20160083514 

N-maleimidyl polymer derivatives


The invention is directed to multi-functional n-maleimidyl polymer derivatives comprising a water soluble and non-peptidic polymer backbone having a terminal carbon, such as a poly(alkylene glycol), the terminal carbon of the polymer backbone being directly bonded to the nitrogen atom of a n-maleimidyl moiety without a linking group therebetween. The invention also provides two methods of preparing such linkerless n-maleimidyl polymer derivatives..
Nektar Therapeutics


03/24/16
20160083484 

Monodisperse glycogen and phytoglycogen nanoparticles and use thereof as additives in cosmetics, pharmaceuticals, and food products


Monodisperse glycogen or phytoglycogen nanoparticles are polyfunctional additives suitable for use in aqueous or alcohol-based cosmetic, pharmaceutical, or food formulations. The nanoparticles may be isolated from various sources (such as corn), and are optionally modified with a range of organic moieties (such as octenyl succinic acid).
Mirexus Biotechnologies Inc.


03/24/16
20160083464 

Functional monoclonal antibody against heparin-binding epidermal growth factor-like growth factor


Two types of antibodies (35-1 antibody and 292 antibody) capable of binding to phenylalanine at position 115, isoleucine at position 117, glycine at position 140, glutamic acid at position 141, and arginine at position 142 of a human hb-egf protein were successfully obtained. Then, it was also found that these antibodies had an activity of suppressing cleavage of the human hb-egf protein, and an activity of suppressing egfr phosphorylation that would occur when the human hb-egf bound to the egfr.
Medical & Biological Laboratories Co., Ltd.


03/24/16
20160083427 

Cyclic cationic peptides with antibmicrobial activity


A series of cationic cyclic peptides, useful for the treatment of infectious diseases in both human and veterinary clinical/surgical environment are described herein. The peptides of the invention have a length of 15 to 21 amino acids, and show a sequence a-b-c-d-c′-b′-a′, wherein units a and a′ correspond to —nh2 terminal and —cooh terminal regions; units b and b′ correspond to cyclizable amino acids containing sulfur; units c and c are sequences of 5 amino acids selected among hydrophobic amino acids, basic amino acids and amino acids forming hydrogen bonds; unit d is a dipeptide consisting of glycine and one basic amino acid.
Azienda Osped Aliero-universitaria Di Parma


03/24/16
20160083415 

Crystalline anhydrate forms of a pharmaceutical


The invention provides and describes solid state 17α-ethynyl-androst-5-ene-3β,7β,17β-triol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates of 17α-ethynyl-androst-5-ene-3β,7β,17β-triol include form i anhydrate and form iv and form v solvates.
Harbor Therapeutics, Inc.


03/24/16
20160083411 

Antidiabetic enolic glucoside of phenylpyruvic acid


There is provided an antidiabetic enolic glucoside of phenylpyruvic acid and derivatives thereof for use as medicaments, especially normoglycemic agents, i.e. For lowering blood glucose levels to normal levels in mammals that are obese, pre-diabetic or have diabetes, obesity and/or syndrome x.
Zadec Aps


03/24/16
20160083337 

Crystal structure of bifunctional transglycosylase pbp1b from e. coli and inhibitors thereof


The crystal structure at 2.16 Å resolution of the full-length bacterial bifunctional transglycosylase penicillin-binding protein 1b (pbp1b) from escherichia coli, in complex with its inhibitor moenomycin, is provided. The atomic coordinates of the complex as well as the moenomycin binding site are provided.
Academia Sinica


03/24/16
20160083329 

Preparation 1-palmitoyl-3-acetylglycerol, and preparation 1-palmitoyl-2-linoleoyl-3-acetylglycerol using same


Disclosed are a method for preparing 1-palmitoyl-3-acetylglycerol in high purity and high yield without a purification process using a column chromatography, and a method for preparing 1-palmitoyl-2-linoleoyl-3-acetylglycerol in high purity and high yield using the same as a key intermediate. The method for preparing 1-palmitoyl-3-acetyl glycerol comprises the steps of: forming a reaction mixture including 1-palmitoyl-3-acetyl glycerol of the formula 1 in the specification by reacting 1-palmitoylglycerol of the formula 2 in the specification and an acetylating agent; and separating the optically active 1-palmitoyl-3-acetylglycerol by crystallizing the reaction mixture in a saturated hydrocarbon solvent having 5 to 7 carbon atoms..
Enzychem Lifesciences Corporation


03/24/16
20160083318 

Process for the preparation of glycols


The invention provides a process for the preparation of ethylene glycol and 1,2-propylene glycol from starting material comprising one or more saccharides, by contacting said starting material with hydrogen in a reactor in the presence of a solvent and a catalyst system with catalytic hydrogenation abilities, wherein the process comprises the steps of: i) introducing a first portion of the starting material into the reactor such that the initial concentration of the saccharide in the solvent in the reactor is no more than 2 wt %; ii) allowing at least 90 wt % of the saccharide in the first portion of the starting material to react; iii) subsequently adding further portions of starting material to the reactor over time; and removing reaction product from the reactor.. .
Shell Oil Company


03/24/16
20160083263 

Preparation metallic oxide spherical cascade structure


A preparation method for a metallic oxide micro-nano spherical cascade structure, belonging to the field of nanometer/micrometer microstructure material and a preparation thereof is provided. The metallic oxide spherical cascade structure of the present invention refers to a micron-sized spherical particle structure composed of metallic oxide powder having a particle size of tens of nanometers.
Nanjing University


03/24/16
20160082153 

Method and system for treatment of damaged biological tissue


Biomaterial compositions and articles comprising mesothelial tissue and a glycosaminoglycan (gag), for treating damaged biological tissue; particularly, damaged cardiovascular tissue. The biomaterial compositions and articles can also include additional biologically active agents, such as growth factors.
Cormatrix Cardiovascular, Inc.


03/24/16
20160082137 

Clinical multimodality-tools for pre-and intraoperative insulinoma diagnostics


A chemical compound has the general formula: ex4-linker-sar(64cu)-fl in which ex4 is an extendin-4 analog; linker is a polyethylene glycol (peg) chain, for example formed with four ethylene glycol residues; fl is a photoluminescent moiety, and sar(64cu) is an atom of copper-64 chelated in a sarcophagine moiety is useful as a multimodality imaging agent for detection and localization of insulinoma cells and β-cell masses.. .
Sloan-kettering Institute For Cancer Research


03/24/16
20160082117 

Low molecular weight polyethylene glycol drug conjugates having improved drug biological activity


Provided are polyethylene glycol drug conjugates of general formula (i), (ii) or (iii) and pharmaceutical compositions and a use thereof. The conjugates are formed by combining low molecular weight polyethylene glycol with 2-4 drug molecules.
Jenkem Technology Co.,ltd.(tianjin)


03/24/16
20160082093 

Mucinous glycoprotein (muc-1) vaccine


The present invention provides a method for treating an individual who is afflicted with a cancer, such as non-small cell lung cancer or prostate cancer, by administering to that individual a muc-1 based formulation. The formulation may be a muc-1 based liposomal vaccine formulation..
Oncothyreon Inc.


03/24/16
20160082075 

Combination therapy for subcutaneous administration of glycopeptide antibiotics


A combination drug therapy is disclosed for the treatment of a patient, such as a human, with a glycopeptide antibiotic. The methods can include subcutaneous administration to a patient of a therapeutically effective amount of a glycopeptide antibiotic, for example, vancomycin, and a compound belonging to the cromones class of anti-inflammatory agents such as cromolyn sodium.
Scpharmaceuticals Inc.


03/24/16
20160082063 

Composition for preventing or treating stroke or degenerative brain disease


The present invention relates to a composition for preventing and/or treating a stroke or a degenerative brain disease comprising: at least two substances selected from the group consisting of egg yolk lecithin, glycerol, sodium oleate, medium chain triglyceride and refined fish oil; olive oil; and soybean oil. The composition of the present invention has an excellent neuroprotective effect but no toxicity or side effects, and thus can be effectively and safely used for preventing, treating or ameliorating a stroke or a degenerative brain disease..
University-industry Cooperation Group Of Kyung Hee


03/24/16
20160082051 

Use of sea cucumber glycosaminoglycan in preparing medicine for prevention and treatment of thromboembolic disease


The present invention discloses use of sea cucumber glycosaminoglycan in the preparation of drugs. In particular, the present invention relates to use of medical use of sea cucumber glycosaminoglycan, and more particularly to use of depolymerized sea cucumber glycosaminoglycan or natural molecular segments of sea cucumber glycosaminoglycan with a weight average molecular weight greater than 54,500 da in the preparation of a drug for the prevention and treatment of thromboembolic diseases.
Heilongjiang Hongdoushan Pharmaceutical Co., Ltd.


03/24/16
20160082050 

Composition, use thereof, and methods of manufacturing


A composition that includes at least two of: echinochrome a (2-ethyl-3,5,6,7,8-pentahydroxy-1,4-naphthoquinone); spinochrome a (2-acetyl-3,5,6,8-tetrahydroxy-1,4-naphthalenedione); spinochrome b (2,3,5,7-tetrahydroxy-1,4-naphthalenedione); spinochrome c (2-acetyl-3,5,6,7,8-pentahydroxy-1,4-naphthalenedione); spinochrome d (2,3,5,6,8-pentahydroxy-1,4-naphthalenedione); and spinochrome e (hexahydroxy-1,4-naphthalenedione). The composition can include one or more additional active ingredients (e.g., vitamin, tretinoin (alltrans retinoic acid or atra), a glycosaminoglycan (gag), dermal filler, botulinum toxin, etc.) and/or one or more inactive ingredients (e.g., solvent, carrier, gelling agent, coloring agent, etc.).
Fertilesea Llc


03/24/16
20160082024 

Use of pentacyclic triterpenoid saponin compound from szechuan melandium root for preparing hypoglycemic drug


The application of pentacyclic triterpenoid saponins, extracted from the plant of silene viscidula, is used to manufacture anti-diabetic medicaments. Having screened and researched the plants and the compounds massively, the compounds of pentacyclic triterpenoid saponins extracted and purified from silene viscidula (hereinafter called wacao saponnins), have strong effects on hyperglycemia, especially for the compounds that have mother nuclei of sinocrassulosides, which can be used to manufacture anti-diabetic medicaments..



Gly topics: Door Assembly, Swimming Goggles, Transverse, Alkoxylate, Fluoropolymer, Air Cleaning, Rotor Shaft, Aspect Ratio, Disconnect, Synchronization, Remote Control, Ethylene Glycol, Surfactant, Combustion, Steviol Glycosides

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