This page is updated frequently with new Gly-related patent applications.
| Method for manufacturing electrode sheet and electrode sheet|
A method for manufacturing an electrode sheet includes the steps of forming a granulated material containing a plurality of granules; forming an electrode mixture layer by molding the granulated material into a sheet; and placing the electrode mixture layer on electrode current collector foil. The step of forming the granulated material includes the steps of forming a granule containing at least an electrode active material and a binder; and adhering a polyglycerol fatty acid ester to a surface of the granule..
Toyota Jidosha Kabushiki Kaisha
| Targeting of chondroitin sulfate glycans|
The present invention relates to functional binding fragments comprising the minimal binding fragments of var2csa, to antibodies against such binding fragments of var2csa, nucleic acids encoding such fragments of var2csa as well as methods for their production. The invention further relates to conjugates and fusion proteins of var2csa polypeptides including the minimal binding fragments and their use, in particular in the treatment of conditions associated with expression of chondroitin sulfate a (csa), such as an inappropriate expression of chondroitin sulfate a (csa)..
Var2 Pharmaceutical Aps
| Enhancement solution for enhancing chemiluminescence and preparing chemiluminescent solution|
Disclosed are an enhancement solution for enhancing chemiluminescence, and a method for preparing a chemiluminescent solution. The method comprises step a: dissolving methylglucamine in water, adjusting the ph to 8-9, then adding an n-alkyldimethylmannosamine quaternary ammonium salt, acridine orange, bsa, glycine, mgcl2, and zncl2 respectively to a diethanolamine solution, stirring to dissolve them, and diluting to a constant volume, to obtain an enhancement solution; and step b: diluting a chemiluminescent substrate with the enhancement solution, to obtain a chemiluminescent solution.
Shenzhen Maxchemtech Co., Ltd.
| Metabolically engineered organisms for the production of added value bio-products|
The present invention relates to genetically engineered organisms, especially microorganisms such as bacteria and yeasts, for the production of added value bio-products such as specialty saccharide, activated saccharide, nucleoside, glycoside, glycolipid or glycoprotein. More specifically, the present invention relates to host cells that are metabolically engineered so that they can produce said valuable specialty products in large quantities and at a high rate by bypassing classical technical problems that occur in biocatalytical or fermentative production processes..
| Method for producing 1,3-propanediol using microorganism variant with deletion of 2,3-butanediol synthetic gene|
The present invention relates to a method for producing 1,3-propanediol using a mutant microorganism lacking a 2,3-butanediol synthetic gene, and more particularly to a mutant microorganism wherein a gene encoding lactate dehydrogenase and a gene encoding an enzyme which is involved in 2,3-butanediol synthesis are deleted in a microorganism having the ability to produce 1,3-propanediol from glycerol and wherein a gene encoding pyruvate decarboxylase and a gene encoding aldehyde dehydrogenase are introduced or amplified, and to a method of promoting the production of 1,3-propanediol while inhibiting the production of 2,3-butanediol by using the mutant microorganism. The use of the glycerol-fermenting mutant microorganism according to the present invention can significantly increase the production of 1,3-propanediol while minimizing the production of 2,3-butanediol..
Korea Research Institute Of Bioscience And Biotechnology
| Method for the production of multiple-unsaturated fatty acids in transgenic organisms|
The present invention relates to a process for the production of polyunsaturated fatty acids in an organism by introducing, into the organism, nucleic acids which encode polypeptides with Δ5-elongase activity. Advantageously, these nucleic acids can be expressed in the organism together with further nucleic acids which encode polypeptides of the biosynthesis of the fatty acid or lipid metabolism.
Basf Plant Science Gmbh
| Modified bacillus cereus phospholipase c protein and processing vegetable oil|
A modified bacillus cereus phospholipase c enzyme is provided, as well as a method of using the modified phospholipase c enzyme in a method of treating vegetable oil. In certain embodiments, this method may comprise combining a vegetable oil with an modified phospholipase c enzyme comprising an amino acid sequence that is at least 85% identical to the amino acid sequence of seq id no:1, wherein the amino acid residue at position 66 is a trp (w) or tyr (y), and maintaining the combination under conditions suitable for the modified phospholipase c enzyme to catalyze the hydrolysis of phospholipids in the oil to produce diacylglycerol and a water soluble phosphate..
| Lipid-based wax compositions substantially free of fat bloom and methods of making|
Lipid-based wax compositions and their methods of making are provided for compositions substantially free of fat bloom. The compositions comprise 0.1-10 percent by weight triacylglycerides, 30-95 percent by weight monoacylglycerides and diacylglycerides combined, and 0.1-65 percent by weight fatty acids.
| Method for preparing a sulfurized alkaline earth metal dodecylphenate|
An overbased sulfurized alkaline earth metal alkylphenate is prepared by reacting an alkylphenol with an alkaline earth metal hydroxide or an alkaline earth metal oxide and sulfur in the presence of an alkylene glycol or dialkylene glycol, or ether thereof and in the presence of an oil of lubricating viscosity, and optionally further reacting the product thereof with carbon dioxide; thereby forming a sulfurized alkaline earth metal alkylphenate composition in oil. The composition is heated and subjected to steam stripping followed by filtration.
The Lubrizol Corporation
| Degradable materials for oil and gas field operations and their synthesis method|
A synthesis method for degradable material(s) (dm) which can be used in oil and gas field operations. The method involves using two, three, four or five polymer and chain extenders, including poly glycolic acid (pga), polycaprolactone (pcl), polylactic acid (pla), poly (butylene succinate) (pbs) and poly(3-hydroxybutyrate) (pha), to synthesize a “resin alloy” through the melt mixing reaction method, which can be used in oil and gas field operations.
Kms Oil Field Chemicals & Technical Services Ltd. Beijing
Electrostatic dissipative polyester tpu and compositions thereof
The present invention relates to an electrostatic dissipative thermoplastic polyurethane composition made by reacting (a) at least one polyester polyol intermediate with (b) at least one diisocyanate and (c) at least one chain extender. The polyester polyol intermediate, may be derived from at least one dialkylene glycol and at least one dicarboxylic acid, or an ester or anhydride thereof.
Lubrizol Advanced Materials, Inc.
Polyester and preparing such a polyester
A polyester, including ethylene 2,5-furandicarboxylateunits, also includes diethylene glycol residues, the content of which is less than 0.045, in moles per mole of 2,5-furandicarboxylate moieties. The polyester composition can be prepared with a method where a starting mixture is subjected to esterification of 2,5-furandicarboxylic acid or transesterification of an ester thereof with ethylene glycol in the presence of a basic compound and/or an ammonium compound capable of suppressing the formation of diethylene glycol..
Furanix Technologies B.v.
Method for purifying immunoglobulin
The present invention relates to a method for purifying an immunoglobulin, and more particularly, to a method for purifying an immunoglobulin, which comprises: dissolving immunoglobulin-containing plasma protein fraction i+ii+iii or fraction ii+iii; adding caprylate to the solution to cause precipitation; performing dialysis and concentration after removal of the precipitate; performing anion exchange resin and ceramic cation exchange resin purification processes to effectively remove a solvent and detergent added to inactivate viruses; and performing elution while maintaining salt concentration at a constant level to maintain the immunoglobulin polymer content at a low level. According to the method for preparing the intravenous immunoglobulin according to the present invention, a precipitation step of preparing fraction ii from fraction i+ii+iii or fraction ii+iii as a starting material can be omitted, and problems, including a complicated process and a low yield, which occur in the conventional preparation process employing the polyethylene glycol treatment process, can be solved by use of first sodium caprylate precipitation, anion exchange chromatography and cation exchange chromatography.
Green Cross Holdings Corporation
The present invention relates to compositions, methods and kits for delivery of active agents (x) to cells or tissues that express proteoglycans. More specifically, the present invention relates to conjugates comprising (hb-linker)n-xm-(linker-hb)o, where hb is a heparin binding protein, x is an active agent such as a therapeutic protein (including a functional fragment or variant thereof), or a therapeutic small molecule, linker is a linker entity and m is an integer of at least 1, and n+o is an integer of at least 1.
The Brigham And Women's Hospital, Inc.
Materials and methods for producing cleaved, hiv-1 envelop glycoprotein trimers
Expression vectors and mammalian cell lines containing them are described that enable the recombinant production of hiv-1 envelope proteins, including sosip modified gp140 trimers capable of inducing broadly neutralizing antibodies.. .
Glycopeptide derivatives for the preservation and protection of biological materials and microorganisms
The present invention relates to a compound of the following formula (i): in which at least one and only one group chosen among r5, r6 and r7 is a group of the following formula: the present invention relates also to uses thereof for preservation and/or protection and/or regeneration of biological materials and or microorganisms and for cosmetic or dermato logical applications such as anti-aging, skin protection and skin regeneration; to culture, storage and/or preservation media comprising such a compound; to cosmetic or dermato logical compositions comprising such a compound; to processes for preparing such a compound; and to synthesis intermediates.. .
Long acting proteins and peptides and methods of making and using the same
Disclosed is a method for refolding a protein or peptide that does not contain essential disulfides and that contains at least one free cysteine residue. Also disclosed are polymer ifn-γ conjugates that have been created by the chemical coupling of polymers such as polyethylene glycol moieties to ifn-γ, particularly via a free cysteine in the protein.
Bolder Biotechnology, Inc.
Dihydropyridinone mgat2 inhibitors for use in the treatment of metabolic disorders
The present invention provides compounds of formula (i): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyltransferase type 2 (mgat2) inhibitors which may be used as medicaments..
Bristol-myers Squibb Company
Tetrazolone-substituted dihydropyridinone mgat2 inhibitors
The present invention provides compounds of formula (i): a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a polymorph, a solvate thereof, wherein all of the variables are as defined herein. These compounds are monoacylglycerol acyl-transferase type 2 (mgat2) inhibitors which may be used as medicaments..
Bristol-myers Squibb Company
Use of n-(1,3,4-oxadiazol-2-yl)arylcarboxamides or their salts for controlling unwanted plants in areas of transgenic crop plants being tolerant to hppd inhibitor herbicides
For controlling unwanted plants in areas of transgenic crop plants being tolerant to hppd inhibitor herbicides by containing one or more chimeric gene(s) comprising (i) a dna sequence encoding hydroxyphenylpyruvate dioxygenase (hppd) derived from a member of a group of organisms consisting of (a) avena, (b) pseudomonas, (c) synechococcoideae, (d) blepharismidae, (e) rhodococcus, (f) picrophilaceae, (g) kordia, or (ii) one or more mutated dna sequences of hppd encoding genes of the before defined organisms, preferably from pseudomonas, or (iii) one or more dna sequences encoding mutated maize (zea mays) or soybean (glycine max) hppd each being mutated as described in wo 2012/021785.. .
Short contact, elevated temperature meg reclamation
Monoethylene glycol (meg) may be reclaimed by a process that includes contacting a meg-water-salt stream with a heat transfer fluid and then flash separating the meg and water in the flash separator vessel where the pressure is higher than 0.3 bara (0.03 mpa), the temperature is in the range of above 120° c. To about 250° c., and the residence time of the meg and water ranges from about 1 second to about 10 minutes, and then removing the meg and water in an overhead of the flash separator vessel and removing the salt from the flash separator vessel.
Cameron International Corporation
Divalent ion removal from monoethylene glycol (meg) feed streams
A system and process for removing divalent ions from a meg feed stream is presented. The system includes a chemical treatment tank where chemicals are mixed with the feed stream to form insoluble carbonate and hydroxide salts.
Cameron Solutions, Inc.
A membrane assembly is provided. The membrane assembly comprises a membrane having a first surface and an opposing second surface, and a layer of anti-fouling polymer selected from the group consisting of an optionally functionalized hyperbranched polyglycerol, a hyperbranched polyimine, a zwitterionic copolymer obtainable by polymerizing 2-methacryloyloxyethyl lipoate with at least one of [2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl) ammonium hydroxide or 2-methacryloyloxyethylphosphorylcholine, and combinations thereof arranged on the first surface of the membrane.
National University Of Singapore
Osteogenic regenerative scaffold matrix composition
The implantable scaffold matrix composition for osteogenic regeneration has a biodegradable polymer material selected from the group consisting of one or more of polylactic acid, polyglycolic acid, or polycaprolactone, or any combination thereof to provide a time release delivery of an osteogenic effect and further has a pharmaceutical composition selected from the group consisting of one or more of ibuprofen, non-steroidal anti-inflammatory drugs (nsaids), acetaminophen, or naproxen sodium or any combination thereof and wherein the implantable composition has a primary and a secondary time release. The primary time release being one of the polymer compositions; each time release extending occurring between 0 days and 19 days, both not being at 0 days.
Nova Southeastern University
Oligosaccharides comprising an aminooxy group and conjugates thereof
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates.
Enolase 1 (eno1) compositions and uses thereof
The invention provides compositions comprising eno1 and a muscle targeting peptide, e.g, as a fusion protein, for delivery of eno1 to a muscle. The eno1 may contain one or more added cysteine residues which are covalently attached to a biocompatible polymer (e.g.
Free raptor reduces aging- and obesity-induced fatty liver
The present invention also provides a method of reducing a subject's hepatic and plasma triglyceride levels comprising administering to a subject in need thereof a pharmaceutical composition comprising a pharmaceutical carrier and a compound that inhibits glucagon signaling in liver cells in an amount effective to reduce the subject's hepatic and plasma triglyceride. .
Brain specific exosome based diagnostics and extracorporeal therapies
Disclosed are methods, compositions, devices, and kits for the isolation of brain-specific exosomes. Specifically, methods, compositions, devices, and unbound kits comprising an isolated brain-specific extracellular vesicle or exosome joined to a first binding agent that is specific for tau, β-amyloid, sloo β, neuron-specific enolase, glycoprotein a2b5, cd133, nq01, synaptophysin, neuronal nuclei, mab 1569, polysialic acid-neural cell adhesion molecule (psa-ncam), or neurogenic differentiation 1 (neurod or beta2), or glycosylated or phosphorylated forms of these molecules, are provided..
Exosome Sciences, Inc.
Method of treating or preventing hyperlipidemia with caffeamide derivatives
The present invention provides a method of treating or preventing hyperlipidemia in a subject in need thereof. Such method includes, specifically, administrating to the subject a therapeutically effective amount of a caffeamide derivative.
Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof
Such compositions can also further comprise various components such as lipids (for example fatty acids, esters thereof or derivatives thereof). Such compositions can be used for example in methods for treating an inflammatory diseases chosen from inflammatory bowel diseases, asthma, acute respiratory distress syndrome, chronic obstructive pulmonary disease, acute lung injury, bronchopulmonary dysplasia, cystic fibrosis, bronchitis, bronchiolitis, arthritis, osteoarthritis, ankylosing spondylitis and rheumatism..
Mitochondrial delivery of 3-bromopyruvate
A mitochondria targeted gold nanoparticle (t-3-bp-aunp) decorated with 3-bromopyruvate (3-bp) and delocalized lipophilic triphenylphosphonium (tpp) cations to target the mitochondrial membrane potential (Δψm) was developed for delivery of 3-bp to cancer cell mitochondria by taking advantage of higher Δψm in cancer cell compared to normal cells. This construct showed remarkable anticancer activity in prostate cancer cells compared to non-targeted construct nt-3-bp-aunp and free 3-bp.
University Of Georgia Research Foundation, Inc.
Water-based color compositions
Inventive embodiments disclosed herein include a water-based formulation that includes silane-modified styrene/acrylic ester copolymer in a concentration of 29.0 percent by weight; polycarbonate polyurethane dispersion in a concentration of 5.0 percent by weight; propylene glycol butyl ether in a concentration of 3.0 percent by weight; and water in a concentration of at least about 53.0 percent by weight.. .
Roasted coffee with resveratrol
The present invention describes new compositions of matter comprising (1) roasted coffee beans in either whole bean form or in ground form to which a formulation containing resveratrol and glycerin and/or specified additional additives have been added, (2) liquid beverages extracted at a pressure of less than 2000 bar from said roasted coffee beans or grounds to which a formulation containing resveratrol and glycerin and/or specified additional additives have been added; and (3) so-called “instant coffee” or “soluble coffee” prepared from roasted coffee beans to which a formulation containing resveratrol and glycerin and/or specified additional additives have been added, but in which a pulverized coffee component is specifically excluded. The formulation including glycerin leads to increased solubility and bioavailability of resveratrol.
Vera Roasting Company, Inc.
Food using soybean powder and manufacturing thereof
The present invention relates to a food comprising soybean powder and an edible fat or oil. More specifically, the present invention relates to a food in which the edible fat or oil contains a triglyceride with a medium-chain fatty acid(s) at a ratio of 50% by mass or higher relative to the mass of the edible fat or oil.
The Nisshin Oillio Group, Ltd.
Ophthalmic and contact lens solutions containing simple saccharides as preservative enhancers
The present invention relates to an ophthalmic solution comprising 0.00001 to 10.0 weight percent of a simple saccharide, at least 0.00001 weight percent of a preservative, and not more than about 0.2 percent by weight chloride. The simple saccharide is chosen from the group consisting of: inositol; mannitol; sorbitol; sucrose; dextrose; glycerin; propylene glycol; ribose; triose; tetrose; erythrose; threose; pentose; arabinose; ribulose; xylose; xylulose; lyxose; hexose; allose; altrose; fructose; galactose; glucose; gulose; idose; mannose; sorbose; talose; tagatose; adlose; ketose; heptose; sedoheptulose; monosaccharides; disaccharides; sugar alcohols; xylitol; and polyol..
Fxs Ventures, Llc
High concentration low voc liquid gibberellin
The invention relates generally to a liquid solution formulation including gibberellic acid (“ga3”), gibberellin4 (“ga4”), gibberellin4/7 (“ga4/7”), or combinations thereof, and a low-volatile, organic solvent, and methods of their use. Specifically, the liquid solution formulations of the present invention are directed toward agricultural liquid solution formulations including at least one gibberellin and a low-volatile, organic solvent selected from polyethylene glycol, propylene glycol, and/or a non-polymeric glycol..
Stoller Enterprises, Inc.
The present invention is directed to an authenticating apparatus, system and a method for authentication of an object or product having a secure glyph thereon. The invention is also directed to the use of the object or product in a machine wherein the secure glyph has an intellectual property protected feature and a machine readable feature..
Sun Chemical Corporation
Process for the attachment of a galnac moiety comprising a (hetero)aryl group to a glcnac moiety, and product obtained thereby
The present invention relates to a process for attaching an n-acetylgalactosamine-(hetero)arylmoiety to an n-acetylglucosaminemoiety, the process comprising the step of contacting the n-acetylgalactosamine-(hetero)arylmoiety with the n-acetylglucosaminemoiety in the presence of a mutant galactosyltransferase, wherein the n-acetylglucosaminemoiety is according to formula (1) the n-acetylgalactosamine-(hetero)arylmoiety is according to formula (2): in a particularly preferred embodiment of the process according to the invention, the n-acetylgalactosamine-(hetero)arylmoiety comprises a 1,3-dipole functional group, and the n-acetylglucosaminemoiety is a terminal glcnac moiety of a glycoprotein glycan. The invention further relates to a product obtainable by the process according to the invention, in particular to glycoproteins.
Vectors and strains for producing myrcene and producing myrcene using the same
Disclosed herein are an expression vector capable of expressing myrcene, an escherichia coli strain transformed with the vector and having improved capability of producing myrcene and a method for producing myrcene and a method for recycling glycerol using the same. In an aspect, the transformed escherichia coli strain of the present disclosure can produce myrcene with high purity on a large scale using glycerol or glucose as a carbon source.
Korea Institute Of Science And Technology
Algal thermoplastics, thermosets, paper, adsorbants and absorbants
Provided are biomass-based materials and valuable uses of microalgal biomass including: (i) acetylation of microalgal biomass to produce a material useful in the production of thermoplastics; (ii) use of triglyceride containing microalgal biomass for production of thermoplastics; (iii) combination of microalgal biomass and at least one type of plant polymer to produce a material useful in the production of thermoplastics; (iv) anionization of microalgal biomass to form a water absorbant material; (v) cationization of microalgal biomass, and optional flocculation, to form a water absorbant material; (vi) crosslinking of anionized microalgal biomass; (vii) carbonization of microalgal biomass; and (viii) use of microalgal biomass in the making of paper.. .
Terravia Holdings, Inc.
Method and generating latent heat at low temperatures using exothermic salt crystallization
A method and apparatus for generating latent heat at low temperatures using an exothermic salt crystallization reaction in a supersaturated solution. The method and apparatus includes a supersaturated solution including a salt-based solute in a solvent.
General Electric Company
Graphene reinforced polyethylene terephthalate
A composition and a method are provided for graphene reinforced polyethylene terephthalate (pet). Graphene nanoplatelets comprising a suitable initial surface area are added to a solvent for producing pet.
Niagara Bottling, Llc
Polyester polymer particles having a small surface to center molecular weight gradient
Polyester polymer particle spheroids comprising a polyester polymer including: a carboxylic acid component containing at least 90 mole % of the residues of terephthalic acid, derivates of terephthalic acid, naphthalene-2,6-dicarboxylic acid, and/or derivatives of naphthalene-2,6-dicarboxylic acid,; and a hydroxyl component containing from 90 to 96 mole % of the residues of ethylene glycol, based on 100 mole percent of the carboxylic acid component residues and 100 mole percent hydroxyl component residues in the polyester polymer, wherein said particle has an kv. Of at least 0.72 dl/g, and the it.v.
Grupo Petrotemex, S.a. De C.v.
Process for making chemical derivatives
Process and methods for making glycolic acid chemical intermediates and derivatives from biomass are described herein.. .