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This page is updated frequently with new Gly-related patent applications.




Date/App# patent app List of recent Gly-related patents
06/16/16
20160172074 
 Multilayer structure having at least one metal layer and at least one polyamide layer patent thumbnailMultilayer structure having at least one metal layer and at least one polyamide layer
A layer structure having at least one metal element and at least one polyamide layer arranged at least regionally on the metal element, the structure preferably comprising an insulated electrical conductor wherein the polyamide layer consists of a polyamide moulding composition consisting of the following components: (a) a polyamide based on cycloaliphatic diamines or cycloaliphatic dicarboxylic acids having a glass transition temperature (tg) of at 130° c.; (b) a polyolefin based on c2-c12 alkenes, and additionally on at least one monomer selected from the following group: maleic anhydride, itaconic anhydride, glycidyl acrylate, butene, propylene, glycidyl methacrylate, acrylic acid, methacrylic acid, vinyl acetate, c1-c12 alkyl (meth)acrylates, substituted or unsubstituted styrene, or a mixture of such monomers; (c) optionally an aliphatic polyamide different from (a), or a mixture of such polyamides; (d) optionally additives.. .
Ems-patent Ag


06/16/16
20160171343 
 Analyzing font similarity for presentation patent thumbnailAnalyzing font similarity for presentation
A system includes a computing device that includes a memory configured to store instructions. The system also includes a processor to execute the instructions to perform operations that include receiving data representing features of a first font and data representing features of a second font.
Monotype Imaging Inc.


06/16/16
20160170941 
 Replicating the appearance of typographical attributes and text adornments in digital publications patent thumbnailReplicating the appearance of typographical attributes and text adornments in digital publications
Techniques are disclosed for replicating the appearance of typographical attributes and text adornments in digital publications. Content in a fixed layout format is converted into a standard digital publication format by applying a <span> tag to each word of the content.
Adobe Systems Incorporated


06/16/16
20160170940 
 Font data streaming patent thumbnailFont data streaming
Provided is a method for font data streaming for time-based video/audio presentations where content is transmitted in small increments and transmission continues while a previously transmitted portion is viewed or played. Different subsets of characters of the same font are assembled together on a device and previously sent characters are reused for rendering subsequent text strings.
Monotype Imaging Inc.


06/16/16
20160168783 
 Fiber structure,  its manufacture and use as well as fiber-resin composite material patent thumbnailFiber structure, its manufacture and use as well as fiber-resin composite material
The invention relates to a fixed and/or stabilized fiber structure from a fibrous material as well as from an agent for its fixing and stabilizing. The agent for fixing and stabilizing is a statistical copolyester which is formed from the diacid components terepththalic acid and, optionally, isophthalic acid as well as the diol components butanediol, diethylene glycol and triethylene glycol.
Ems Patent Ag


06/16/16
20160168742 
 Method for anodizing aluminum alloy workpiece,  surface treating aluminum alloy workpiece, and anodizing solution mixes patent thumbnailMethod for anodizing aluminum alloy workpiece, surface treating aluminum alloy workpiece, and anodizing solution mixes
A method for surface treating an aluminum alloy workpiece having zinc and magnesium includes: providing the aluminum alloy workpiece; polishing the aluminum alloy to achieve a mirror effect; degreasing the aluminum alloy workpiece; stripping a black film formed on the aluminum alloy workpiece; anodizing the aluminum alloy workpiece in an anodizing solution which includes acidic solution and an additive with a concentration of 0.5 mg/l to 25 g/l to form an oxidation film on the surface of the aluminum alloy workpiece, wherein the additive including at least one compound selected from a group consisting of adipic acid, 1,2,3-benzotriazole, oxalic acid, sodium malate, and glycerin; and sealing the aluminum alloy workpiece. This disclosure further provides an anodizing solution applied in the method for surface treating an aluminum alloy workpiece and a method for anodizing the aluminum alloy workpiece using the same..
Hon Hai Precision Industry Co., Ltd.


06/16/16
20160168738 
 Additive for reducing voids after annealing of copper plating with through silicon via patent thumbnailAdditive for reducing voids after annealing of copper plating with through silicon via
An additive for reducing voids after annealing of copper plating with through silicon via. The additive contains by weight percent: 0.05-1% of one or more of quaternized polyethylene imine and derivatives thereof having different molecular weights, and 1-10% of polyethylene glycol with an average molecular weight of 200-20000.
Shanghai Sinyang Semiconductor Materials Co., Ltd.


06/16/16
20160168737 
 Additive c capable of changing microvia-filling method by tsv copper plating, and electroplating solution containing same patent thumbnailAdditive c capable of changing microvia-filling method by tsv copper plating, and electroplating solution containing same
An additive c capable of changing microvia-filling method by tsv copper plating, and electroplating solution containing same. The additive c contains by mass percentage: 5%-10%, one of polyethylene glycol or polyvinyl alcohol with the molecular weight of 200-100,000, or the mixture with different molecular weight thereof; 0.001%-0.5% isomer of the surfactant which including the alkylphenol polyoxyethylene ether or fatty alcohol-polyoxyethylene ether; and the solvent is water.
Shanghai Sinyang Semiconductor Materials Co., Ltd.


06/16/16
20160168627 
 Escherichia coli as a marker for hypertriglyceridemia patent thumbnailEscherichia coli as a marker for hypertriglyceridemia
The present invention relates to predicting the risk of developing hypertriglyceridemia in a subject by quantitating the amount of enterobacteria, e.g., e. Coli, in the subject's gastrointestinal system.
Nestec S.a.


06/16/16
20160168618 
 Method for diagnosing cancer through detection of deglycosylation of glycoprotein patent thumbnailMethod for diagnosing cancer through detection of deglycosylation of glycoprotein
Provided is a method for diagnosing cancer through a difference with a control group in view of the ratio of a deglycosylated peptide fragment and a non-glycosylated peptide fragment in a protein including an n-linked glycosylation motif. Further provided is a method for diagnosing cancer through the detection of the glycosylation ratio in the protein according to the subject matter enables the diagnosis of cancer with high specificity and sensitivity using at least one existing marker, and can be useful in discovering new markers for diagnosing cancer..
Seoul National University R&db Foundation


06/16/16
20160168504 

Low viscosity gear oil composition providing enhanced fuel efficiency


A gear oil composition includes base oil including poly-alpha-olefin (pao) synthetic oil in 70 to 95% by weight and oil-soluble polyalkylene glycol (osp) synthetic oil in 5 to 30% by weight based on the weight of the base oil. The gear oil further includes a polyalkyl methacrylate-based viscosity modifer in 5 to 20 parts by weight, based on 100 parts by weight of the base oil..
Hyundai Motor Company


06/16/16
20160168446 

Method for producing mineral oil from an underground mineral oil deposit using a composition (z) comprising a glycerol-boric acid complex


The present invention relates to a method for producing mineral oil from an underground mineral oil deposit using a composition (z) and to the use of the composition (z) as a medium for mineral oil production.. .
Institute Of Petroleum Chemistry Of The Siberian Branch Of The Russian Academy Of Sciences


06/16/16
20160168435 

Adhesive system for lignocellulosic substrates having high levels of extractives


An adhesive system for preparing lignocellulosic composites comprising: a) a primer composition; and, b) a polyurethane adhesive composition, wherein said primer composition comprises: 1 to 100% by weight of the composition of at least one compound having a hydroxyl number of less than or equal to 30 mg koh/g and being selected from the group consisting of polyalkylene glycols, polyalkylene glycol mono-ethers or polyalkylene glycol di-ethers; 0 to 99% by weight of the composition of solvent; and, 0 to 5% by weight of the composition of surfactant selected from the group consisting of water soluble surfactants, water emulsifiable surfactants and mixtures thereof. The adhesive system has particular applicability to wooden substrates characterized by high levels of water soluble extractives and, in particular, arabinogalactan..
Henkel Ag & Co. Kgaa


06/16/16
20160168431 

High performance sealant composition for tire repair


A high performance sealant for repairing punctures in tires includes a highly filtered natural rubber latex, an ultra-fine inorganic powder, a polyamide suspension, and an antifreeze agent that includes water and at least one of ethylene glycol and propylene glycol. The high performance sealant can readily pass through a valve stem of a tire without removing the core and seal, and provides a strong and durable sealing of the puncture..
Illinois Tool Works Inc.


06/16/16
20160168379 

Binder composition for sublimation printing natural fibers


A binder composition for sublimation-printing natural fibers of the present invention includes: (a) an aqueous solvent; (b) a moisture evaporation retardant selected from urea, glycerine, and a mixture thereof; (c) a (meth)acrylic polymer; (d) a polyurethane; (e) a blocked polyisocyanate; and (f) a paraffin wax.. .

06/16/16
20160168227 

Composition and vaccine for treating lung cancer


The present invention relates to a composition comprising at least one mrna encoding a combination of antigens capable of eliciting an (adaptive) immune response in a mammal, wherein the antigens are selected from the group consisting of 5t4 (trophoblast glycoprotein, tpbg), survivin (baculoviral tap repeat-containing protein 5; birc5), ny-eso-1 (new york esophageal squamous cell carcinoma 1, ctag1b), mage-c1 (melanoma antigen family c1), mage-c2 (melanoma antigen family c2), and muc1 (mucin 1). The invention furthermore relates to a vaccine comprising at least one mrna encoding such a combination of antigens, and to the use of said composition (for the preparation of a vaccine) and/or of the vaccine for eliciting an (adaptive) immune response for the treatment of lung cancer, preferably of non-small cell lung cancer (nsclc), and diseases or disorders related thereto.
Curevac Ag


06/16/16
20160168216 

Methods of using compositions comprising variants and fusions of fgf19 polypeptides for reducing glucose levels in a subject


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21), and variants or fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168215 

Compositions comprising variants and fusions of fgf19 polypeptides


The invention relates to variants and fusions of fibroblast growth factor 19 (fgf19), variants and fusions of fibroblast growth factor 21 (fgf21), fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21), and variants or fusions of fibroblast growth factor 19 (fgf19) and/or fibroblast growth factor 21 (fgf21) proteins and peptide sequences (and peptidomimetics), having one or more activities, such as glucose lowering activity, and methods for and uses in treatment of hyperglycemia and other disorders.. .
Ngm Biopharmaceuticals, Inc.


06/16/16
20160168204 

Method for purifying oligosaccharide peptide


The present invention provides a method for conveniently purifying sialyl glycopeptide from an egg yolk component, comprising the step of mixing a deproteinizing agent with an aqueous solution containing an avian egg yolk component to obtain a dissolved portion.. .
Daiichi Sankyo Company, Limited


06/16/16
20160168044 

Converting glycerol to propylene


Processes relating to a one-step conversion to directly produce propylene from glycerol with a hydrotreating catalyst under a constrained hydrogen/glycerol feed ratio.. .
Phillips 66 Company


06/16/16
20160167279 

Pef container, preform & the manufacture of said container by injection stretch blow-molding


A preform, which makes it possible to obtain pef containers (bottles) having the awaited properties, notably mechanical, by an industrial injection stretch blow molding process, is of made of a thermoplastic pef polymer of 2,5-furandicarboxylic acid (2,5-dca) monomer and monoethylene glycol (meg) monomer and comprises a neck end 2, a neck support ring 3, and a closed tubular body portion 4. The preform is designed so as to produce, by injection stretch blow-molding, a container, the axial stretch ratio of which is greater than or equal to its hoop stretch ratio.
Societe Anonyme Des Eaux Minerales D'evian Et En Abrege "s.a.e.m.e."


06/16/16
20160166700 

Method for ameliorating liver fibrosis by using nanoparticle containing tyrosine kinase inhibitor


The present invention is related to a method for ameliorating liver fibrosis in a subject. The present invention utilizes copolymers of polyethylene glycol and poly (d, l-lactide-co-glycolide) to form nanoparticle composition containing tyrosine kinase inhibitor, such as sorafenib.
National Tsing Hua University


06/16/16
20160166699 

Oral composition for delivery of drugs and other substances


The present disclosure provides for a composition which may be used for the solublization of an agent or the oral administration of an agent, the composition comprising, a lyosphosphatidyl compound and at least one of a monoglyceride and a free fatty acid. In certain embodiments, the composition comprises a lyosphosphatidyl compound, a monoglyceride and a free fatty acid.
Avanti Polar Lipids, Inc.


06/16/16
20160166694 

Pharmaceutical composition, preparation and methods of treating aches/pains


Provided are methods and compositions useful for treating/aches and/or pains. The compositions include ibuprofen in a clear stable aqueous system of water, alcohol and glycerin that is stable at room temperature for at least 6 months without separation or precipitation.
Avanti Pharma Corporation


06/16/16
20160166663 

Vaccine formulations that induce a th2 immune response


The present invention relates to compositions and methods for the prevention and treatment of neurodegenerative diseases, such alzheimer's disease, that are caused by misfolding, aggregating proteins. The compositions and methods of the present invention comprise a vaccine formulation comprising an antigen selected from the group consisting of i) amyloid-β or a peptide that has in its amino acid sequence part of the amyloid-β amino acid sequence, ii) hyperphosphorylated tau protein or one of its hyperphoshorylated peptides, or iii) a combination of antigens derived from groups i) and ii) and that are formulated with a non-acylated or deacylated, natural or synthetic, bidesmosidic triterpene glycoside carrying an aldehyde or ketone group, which acts as an adjuvant or immune agonist.
Qantu Therapeutics, Inc.


06/16/16
20160166655 

Hemostatic compositions


The invention relatesto a hemostatic composition in powder form comprising collagen of the fibrillar type comprising a content of fibrous collagen and/or fibrillar collagen of at least 70% by weight relative to the total weight of the collagen, and at least one monosaccharide, and optionally, at least one compound selected from coagulation factors and glycosaminoglycans. The invention further relates to a method for preparing such composition, and to a unit comprising such composition and a spraying device..
Biom'up


06/16/16
20160166647 

Pegylated interleukin-10


Interleukin-10 (il-10) conjugated via a linker to one or more polyethylene glycol (peg) molecules at a single amino acid residue of the il-10, and a method for preparing the same, are provided. The method produces a stable mono-pegylated il-10, which retains il-10 activity, where pegylation is selective for the n-terminus on one subunit of il-10 with little or no formation of monomeric il-10.
Merck Sharp & Dohme Corp.


06/16/16
20160166528 

Compositions containing monoacetyldiacylglycerol compound as an active ingredient for preventing or treating rheumatoid arthritis


The invention relates to pharmaceutical compositions, as well as health functional food compositions and quasi-drug compositions, for preventing, treating, or improving rheumatoid arthritis, comprising a monoacetyldiacylglycerol compound as an active ingredient. The monoacetyldiacylglycerol of the invention is effective in inhibiting the phosphorylation of stat-3 known to be a therapeutic target for rheumatoid arthritis.
Enzychem Lifesciences Corporation


06/16/16
20160166527 

Glyceride composition


A composition for use in developing and/or improving brain function comprises a glyceride having a palmitoyl group at the 2-position wherein at least 40% by weight of the palmitic acid content of the composition is present as palmitoyl groups bonded at the 2-position of a glyceride.. .
Loders Croklaan B.v.


06/16/16
20160166489 

Gel-based sugar scrub


Disclosed is a stable gel comprising a gel matrix comprising polyethylene glycol and surface treated silica, wherein the gel matrix is formed with the polyethylene glycol and surface treated silica, and particulate sugar dispersed throughout the gel matrix, wherein the gel has less than 5 wt. % oil..
Mary Kay Inc.


06/16/16
20160165941 

Sugar substitute compositions comprising digestion resistent soluble fiber


What is provided are sugar substitute compositions comprising natural ingredients that provide added human health benefits and properties and characteristics of sugar, without the caloric content and glycemic index of sugar. Unlike artificial sweeteners, the sugar substitute compositions contain no chemicals or synthetic additives and taste and function like sugar.
Flipn'sweet, Llc


06/16/16
20160165939 

Stevia coated sugar granules and manufacturing the same


A low-calorie sweetener composition, and method of manufacturing the same. The method includes providing a first sweetener having a mean particle size of between 100-350 μm in diameter and coating the first sweetener with a second sweetener in an aqueous solution.
Eco Sweeteners Llc


06/16/16
20160165938 

Stevia composition


Stevia compositions are prepared from steviol glycosides of stevia rebaudiana bertoni. The compositions are able to provide a superior taste profile and can be used as sweetness enhancers, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals..
Purecircle Usa, Inc.


06/16/16
20160165892 

Pentacyclic triterpene compounds and uses thereof


Disclosed herein is a pegylated bis pentacyclic triterpene, compositions comprising the pegylated bis pentacyclic triterpene, methods of preparing the pegylated bis pentacyclic triterpene, and a method of treating or preventing a fungal disease in a plant using the compounds and compositions disclosed herein. The pegylated bis pentacyclic triterpene has the formula a-p-b, wherein a is a first pentacyclic triterpene; b is a second pentacyclic triterpene; and p is a polyethylene glycol (peg) molecule..
Biovectra Inc.


06/09/16
20160160247 

Modified algae strain and triacylglycerol accumulation using said strain


The present invention relates to a genetically engineered algae strain in which the expression of the cgi-58 gene or homologous gene thereof is silenced. The present invention further relates to a method of triacylglycerol accumulation using said genetically engineered diatom and/or diatom strain..
Commisariat A L'energie Atomique Et Aux Energies Alternatives


06/09/16
20160160188 

Peg-urate oxidase conjugates and use thereof


A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as peg), wherein an average of 2 to 10 strands of peg are conjugated to each uricase subunit and the peg has an average molecular weight between about 5 kda and 100 kda. The resulting peg-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme..
Crealta Pharmaceuticals Llc


06/09/16
20160160154 

Conjugated linoleic acid rich vegetable oil production using heterogeneous catalysis


The invention is directed to cla-rich vegetable oil production from linoleic rich oils by heterogeneous catalysis. The process produces conjugated pufa in triglyceride form, preferably at least 20% cla-rich, by isomerization of a non-conjugated pufa in vegetable oils using a heterogeneous transition metal catalyst promoted by an organic acid and/or thiol-containing compound.
Board Of Trustees Of The University Of Arkansas


06/09/16
20160160118 

Fracturing fluid for prevention of shale fracture hydration during well stimulation by hydraulic fracturing


Friction reducers for hydraulic fracturing fluids, hydraulic fracturing fluids containing the friction reducers, and methods of making and using same are disclosed. The friction reducers comprise ethylene oxide polymers, propylene oxide polymers, ethylene oxide-propylene oxide co-polymers, and combinations thereof, and can further comprise a dispersant, such as polypropylene glycol.

06/09/16
20160159979 

Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator


Wherein ra1a and ra1b each independently represent a protective group of the amino group, or one of ra1a and ra1b represents h and the other represents a protective group of the amino group, or ra1a and ra1b bind to each other to represent a cyclic protective group forming a ring; ra2 represents a linear, branched, or cyclic hydrocarbon group having 1 to 6 carbon atoms; ra3 represents a single bond, or a linear, branched, or cyclic hydrocarbon group having 1 to 20 carbon atoms, and the hydrocarbon group may contain a heteroatom; the total number of carbon atoms (or the total number of carbon atoms and heteroatoms) of ra2 and ra3 is 4 or more; and m represents an alkali metal.. .

06/09/16
20160159976 

Toner binder and toner


A toner binder comprising a polyester, the end of which is partially esterified with a monocarboxylic acid and/or a monohydric alcohol, the polyhydric alcohol component of which comprises a c3 alkylene glycol (a21) and an aromatic-ring-bearing diol (a22) at an (a21)/(a22) molar ratio of 5/95 to 70/30, and which has an ester group concentration of 16 to 30 wt % and satisfies a specific relationship between the ester group concentration and the hydroxy value. The toner binder combines low-temperature fixability and storage stability under high-temperature conditions or heat-temperature and -humidity conditions, and exhibits excellent durability..
Sanyo Chemical Industries, Ltd.


06/09/16
20160159864 

Complexes of cytomegalovirus proteins


This disclosure provides an isolated human cytomegalovirus (hcmv) membrane protein complex, wherein said complex comprises gh, gl and at least one more hcmv glycoprotein. In some embodiments the complex consists of gh, gl and go.
Novartis Ag


06/09/16
20160159858 

Uric acid-lowering agent


A uric acid-lowering agent containing, as an active ingredient, a tyrosine-containing cyclic dipeptide selected from the group consisting of cyclotryptophanyltyrosine, cycloseryltyrosine, cycloprolyltyrosine, cyclotyrosylglycine, cyclotyrosyltyrosine, cyclophenylalanyltyrosine, cycloleucyltyrosine, cyclolysyltyrosine, cyclohistidyltyrosine, cycloalanyltyrosine, cycloglutamyltyrosine, cyclovalyltyrosine, cycloisoleucyltyrosine, cyclothreonyltyrosine, cycloaspartyltyrosine, cycloasparaginyltyrosine, cycloglutaminyltyrosine, cycloarginyltyrosine, cyclomethionyltyrosine, and cyclotyrosylcysteine, or a salt thereof. The uric acid-lowering agent of the present invention has an excellent action of lowering a uric acid level, and the uric acid-lowering agent is useful in, for example, prevention or treatment of hyperuricemia, gout or the like..
Suntory Holdings Limited


06/09/16
20160159831 

Method for producing polyalkylene glycol derivative having amino group at end


Wherein ra1a and ra1b each independently represent a protective group of the amino group, or one of ra1a and ra1b represents h and the other represents a protective group of the amino group, or ra1a and ra1b bind to each other to form a cyclic protective group, and the protective group is deprotectable without using a heavy metal; ra2 represents a linear, branched, or cyclic hydrocarbon group having 1 to 6 carbon atoms; and x represents a leaving group.. .

06/09/16
20160159814 

Glycine transporter inhibitor


Which are useful in the prevention or treatment of diseases such as schizophrenia, alzheimer's disease, cognitive impairment, dementia, anxiety disorders (e.g., generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, social anxiety disorder, post-traumatic stress disorder, specific phobias, acute stress disorder), depression, drug dependence, spasm, tremor, pain, parkinson's disease, attention deficit hyperactivity disorder, bipolar disorder, eating disorder, or sleep disorders, which is based on the glycine uptake-inhibiting action.. .

06/09/16
20160159687 

Anti-static agent for glass fiber insulation


A composition includes glass fibers and a polyether antistatic agent. The polyether antistatic agent has a molecular weight of less than about 2000, or less than about 1000.
Johns Manville


06/09/16
20160158729 

Catalytic composition, making and catalytic application thereof for producing ester(s) of glycerol


In accordance with the present subject matter there is provided a process for producing mono-, di- and triesters of glycerol over a catalyst composition. The catalyst composition including a base catalyst and a support material based on phyllosilicates of montmorillonite structure and the process for preparing the catalyst composition is also described..
Bharat Petroleum Corporation Limited


06/09/16
20160158421 

Compositions and methods for coating implant surfaces to inhibit surgical infections


Infection-inhibiting compositions suitable for coating surfaces of implantable medical implants, including compositions and devices for coating medical devices in the operating room prior to implantation in a patient. Methods for inhibiting infection at the site of implantation of an orthopedic device in a human or animal subject, comprise rubbing a surface of the device, prior to implantation, with an infection-inhibiting composition having a waxy matrix comprising an infection-inhibiting material selected from the group consisting of a lipid, an antimicrobial agent, and mixtures thereof, wherein a thin layer of the infection-inhibiting material is deposited on the surface of the device.
Biomet Manufacturing, Llc


06/09/16
20160158408 

Irrigation resistant compositions for regeneration of hard tissues and methods of using the same


An irrigation resistant bone repair composition including a biocompatible or bioactive bone repair material comprising borate, and poly(glycerol sebacate), wherein the composition, upon implantation into a surgical site, maintains position and does not displace upon irrigation of the surgical site, is described. Also, methods for treating a bone having a bone gap or a bone defect with the composition as well as kits that include the composition, are provided..
Novabone Products, Llc


06/09/16
20160158389 

Imaging tumor glycolysis by non-invasive measurement of pyruvate kinase m2


A novel pyruvate kinase m2 (pkm2)-specific activator, [11c]dasa-23 and derivatives thereof, and methods for their rapid synthesis are provided. The probes are particularly useful in methods for the non-invasive positron emission tomography (pet) detection and imaging of pkm2 expression in subcutaneous and orthotopic tumors.
The Board Of Trustees Of The Leland Stanford Junior University


06/09/16
20160158387 

Coated magnetic nanoparticles


Disclosed herein are polymer-coated iron oxide magnetic nanoparticles and methods of their manufacture and use. The nanoparticles are coated with a copolymer of poly(maleic anhydride alt-h2c═ch—r1)-polyethylene glycol (pmar-peg), wherein r1 is a hydrophobic moiety.
University Of Washington Through Its Center For Commercialization


06/09/16
20160158382 

Agent for the treatment and prevention of sleep disorders


The invention relates to the fields of pharmaceutics and medicine and describes an agent for the treatment and prevention of sleep disorders, wherein a conjugate of glycine immobilized on detonation nanodiamond particles 2-10 nm in size comprises 21±3 wt. % glycine.

06/09/16
20160158362 

Liquid bendamustine formulation


The present invention provides stable bendamustine-containing pharmaceutical compositions suitable for long term storage. The compositions include bendamustine, a pharmaceutically acceptable salt, and/or a hydrate form thereof, a solvent mixture of n,n-dimethylacetamide and glycerin, and an antioxidant.

06/09/16
20160158340 

Influenza vaccines containing hemagglutinin and matrix proteins


An immunological composition comprising influenza virus haemagglutinin and matrix proteins. These may be from influenza viruses grown in call culture rather than eggs.
Seqirus Uk Ltd.


06/09/16
20160158281 

Surface-modified heavy metal nanoparticles, compositions and uses thereof


Surface-modified heavy metal nanoparticles, including a heavy metal core and a coating layer, the coating layer having at least one ligand, conjugated to polyethylene glycol, the at least one ligand is selected from n-acetyl cysteine, albumin, cysteine, methionine, glutathione, amino thiols, thio-carboxylic acids, ammonia, amines, diamines or any combination thereof. Compositions including surface-modified heavy metal nanoparticles and uses thereof in treatment and diagnosis of various conditions..
Metallo Therapy Ltd.


06/09/16
20160158271 

Inhibitors of adamts4 or adamts5 for use in preventing or treating cardiac remodeling and chronic heart failure


The present invention provides an inhibitor of an adamts proteoglycanase for use in treating or preventing cardiac remodeling or for use in treating or preventing heart failure in a subject. In particular, the present invention provides an inhibitor of adamts4 or adamts5 for use in treating or preventing cardiac remodeling or chronic heart failure in a subject with cardiac remodeling or with chronic heart failure, or with a condition that may lead to cardiac remodeling and/or chronic heart failure.
Universitetet I Oslo


06/09/16
20160158264 

Pharmaceutical composition, methods for treating and uses thereof


The invention relates to the treatment or prevention of one or more conditions selected from type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance and hyperglycemia using a sglt-2 inhibitor. In addition the present invention relates to methods for preventing or treating of metabolic disorders and related conditions..
Boehringer Ingelheim International Gmbh


06/09/16
20160158248 

Methods and systems for the delivery of a therapeutic agent


The present invention provides a liquid pharmaceutical composition comprising a therapeutic agent and an alkoxy-polyethylene glycol, for example, methoxy-polyethylene glycol, for administration of the therapeutic agent to the mammal. The compositions can be applied to a membrane, for example, a nasal membrane during intranasal administration.
University Of Iceland


06/09/16
20160158183 

Compositions and methods comprising medium chain triglycerides for treatment of epilepsy


The invention provides compositions and methods for treatment of epilepsy in an animal. In one embodiment, a dietary regime suitable for enhancing the effect of an anti-epileptic drug (aed) in an animal can comprise a food composition comprising a medium chain triglyceride (mct) and the aed, wherein the mct is present in the food composition in an effective amount for enhancing the effect of the aed when the food composition and the aed are administered to the animal..
Nestec Sa


06/09/16
20160157505 

Coagulant composition for tofu and production process of tofu using the same


An object of the present invention is to provide a coagulant composition for tofu exhibiting high dispersibility in soy milk, even when the composition comprises a large proportion of an inorganic salt coagulant. The composition requires no use of a specially designed coagulating machine equipped with a high-speed dispersion mixer, and is thoroughly dispersed in soy milk merely by mixing with conventional low-speed stirrer.
Riken Vitamin Co., Ltd.


06/02/16
20160153946 

Oxygen detection agent composition, oxygen detection sheet, packaging material for oxygen scavenger, and oxygen scavenger package


The provision of an oxygen detecting agent composition comprising polyethylene glycol, a redox dye, a reducing agent, and a basic substance, wherein a content of the polyethylene glycol is 5 to 35% by mass based on a total amount of the oxygen detecting agent composition, and the basic substance is a poorly water-soluble basic substance having a solubility in water of less than 1 g/100 g-h2o at 20° c., the oxygen detecting agent composition comprising substantially no trisodium phosphate.. .
Mitsubishi Gas Chemical Company, Inc.


06/02/16
20160153871 

Cytoplasmic stain composition


Disclosed is a composition of cytoplasm stain for use in differentiation of cell nuclei from cell cytoplasmic components and differentiation of specific cytoplasm components by tinctorial contrast. Specifically, the invention relates to stain composition utilized as a counter stain in the hematoxylin and eosin procedure for use in histological and cytological microscopic evaluation of tissue and cells.

06/02/16
20160153024 

Quantification of non-reducing end glycan residual compounds for determinging the presence, identity, or severity of a disease or condition


Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.. .
Biomarin Pharmaceutical Inc.


06/02/16
20160153019 

Production of glycoproteins having increased n-glycosylation site occupancy


The present disclosure relates to compositions and methods useful for the production of heterologous proteins with increased n-glycosylation site occupancy in filamentous fungal cells, such as trichoderma cells. More specifically, the invention provides a filamentous fungal cell comprising i.
Glykos Finland Oy


06/02/16
20160153018 

Non-caloric sweeteners and methods for synthesizing


Disclosed are steviol glycosides referred to as rebaudioside v and rebaudioside w. Also disclosed are methods for producing rebaudioside m (reb m), rebausoside g (reb g), rebaudioside ka (reb ka), rebaudioside v (reb v) and rebaudioside (reb w)..
Conagen Inc.


06/02/16
20160152979 

Novel compounds


Wherein q is a q10 moiety, such as ubiquinone; l, which is optionally included, is a linker selected from the group consisting of polyesters, polyethers, polyamines, polyamides, peptides, carbohydrates, lipids, c3-12 alkyl straight chain based linkers, polyethylene glycols and other polymeric compounds; and a1 is a nucleotide moiety. Disclosed are also pharmaceutical compositions comprising such compounds or pharmaceutically acceptable salts thereof.

06/02/16
20160152974 

Compounds and methods for modulating apolipoprotein c-iii expression for improving a diabetic profile


Provided herein are improved compounds, compositions and associated methods for reducing expression of apociii mrna and protein in a subject having, or at risk of having, diabetes. Also provided herein are compounds, compositions and associated methods improving peripheral insulin sensitivity, a lipid profile and a diabetes profile as well as reducing free fatty acids and intramyocellular triglyceride deposition..
Ionis Pharmaceuticals, Inc.


06/02/16
20160152924 

Process for converting low and high free fatty acid containing oils into no free fatty acid containing oils and associated systems and devices


The disclosed apparatus, systems and methods relate to the conversion of high free fatty acid (“hffa”) containing oils defined as oils containing 20-100% free fatty acids (“ffa”) and low free fatty acid (“lffa”) containing oils defined as oils containing 1-20% free fatty acids (ffa) into oil with less than about 0.5-1% ffa. If the feedstock is hffa oil, the process includes a combination of partial glycerolysis of hffa oils to produce lffa oils and subsequent stripping of lffa oils to produce nffa oils via steam distillation.
Technochem


06/02/16
20160152908 

Method for preparing fatty acid alkyl ester using fat


Disclosed is a method for preparing fatty acid alkyl ester for bio-diesel fuels by reacting a raw material containing fat with water to prepare fatty acid, and then reacting the prepared fatty acid with alcohol. The method for preparing fatty acid alkyl ester for bio-diesel fuels includes the steps of: preparing fatty acid and glycerin by an hydrolysis reaction of a raw material containing fat and water at the temperature of 200 to 280° c.
Sk Chemicals Co., Ltd.


06/02/16
20160152883 

Composition for use in conducting downhole operations in oil and gas wells


A composition for viscosifying a nonaqueous base liquid. The composition has glycerin carbonate and optionally an alkoxylated alcohol having the formula: wherein r is a linear or branched alkyl from 2 to 18 carbon atoms, or an aromatic radical having the structure: where r1 is a branched or linear alkyl having from 2 to 18 carbon atoms r2 is h or ch3 r3 is h or ch3 a is from 0 to 12 and b is from 1 to 12.

06/02/16
20160152844 

Complex oligomeric structures


Said c6-c24 dicarboxylic acid residues of r2 and r3 being esterified with monoalcohols and said mixture of triglycerides having a numerical average molecular weight (mn) of between 800 and 10.000 da.. .

06/02/16
20160152696 

Antibodies to ß2-glycoprotein i and therapeutic uses thereof


Human recombinant antibodies or fragments thereof having specificity for the β2-glycoprotein i (β2gpi), pharmaceutical compositions containing same and use thereof in a method for treating or preventing thrombus formation and fetal loss in a patient affected by antiphospholipid syndrome (aps).. .
Onconox Aps


06/02/16
20160152653 

Novel aminoglycoside antibiotics


This invention relates to novel aminoglycoside antibiotics, which have potent antimicrobial activity against bacteria, which induce infectious diseases, particularly mrsa, and has no significant nephrotoxicity, and process for producing them. More particularly, the present invention relates to compounds represented by formula (ia) or their pharmacologically acceptable salts or solvates, or their diastereomer mixtures, antimicrobial agents comprising them, and a process for producing them..
Microbial Chemistry Research Foundation


06/02/16
20160152564 

Method for stepwise separating amino acid active ingredients of camellia nitidissima chi


The present invention relates to the technical field of camellia nitidissima chi processing and application, and provides a method for stepwise separating amino acid active ingredients of camellia nitidissima chi. The method comprises the following steps: taking a graphene nano material as a selective extraction, adsorption and separation carrier material; carrying out stepwise separation through stepwise controlling the ph value of camellia nitidissima chi concentrated solution and adjusting the isoelectric points of the amino acid active ingredients, wherein the amino acid active ingredients comprise aspartic acid, threonine, serine, glutamic acid, praline and glycine, and the ph values of the aspartic acid, the threonine, the serine, the glutamic acid, the proline and the glycine corresponding to the stepwise separated isoelectric points are less than 2,77, 5.98-6,15, 3.23-5.67, 2.78-3.21, 6.17-6.29 and 5.69-5.96.
School Of Medicine Jiaying University


06/02/16
20160151535 

Poly(oligoethylene glycol methacrylate) hydrogel compositions, and methods of use thereof


The present application relates to hydrogel compositions comprising first and second precursor polymers, wherein the precursor polymers are modified poly(oligoethylene glycol methacrylate) copolymers that are crosslinked through electrophile-nucleophile reactions.. .
Mcmaster University


06/02/16
20160151511 

Proteins and protein conjugates with increased hydrophobicity


Examples may include a method of making a protein-peg conjugate salt with increased hydrophobicity. The method may include providing an aqueous protein solution.
Antriabio, Inc.


06/02/16
20160151510 

Proteins and protein conjugates with increased hydrophobicity


Examples may include a method of making a protein-peg conjugate salt with increased hydrophobicity. The method may include providing an aqueous protein solution.
Antriabio, Inc.


06/02/16
20160151509 

Enzyme and receptor modulation


Covalent conjugates of an α,α-disubstituted glycine ester and a modulator of the activity of a target intracellular enzyme or receptor, wherein the ester group of the conjugate is hydrolysable by one or more intracellular carboxylesterase enzymes to the corresponding acid and the α,α-disubstituted glycine ester is conjugated to the modulator at a position remote from the binding interface between the inhibitor and the target enzyme or receptor pass into cells and the active acid hydrolysis product accumulates within the cells.. .
Glaxosmithkline Intellectual Property Development Limited


06/02/16
20160151506 

Glycosaminoglycan derivative and producing same


The present invention provides a glycosaminoglycan derivative in which a group derived from glycosaminoglycan and a group derived from a physiologically active substance having at least one of a carboxy group and a hydroxy group are coupled by covalent bond with a spacer therebetween, in which the spacer is selected in accordance with the decomposition rate of the covalent bond to the group derived from the physiologically active substance.. .
Seikagaku Corporation


06/02/16
20160151497 

Ph sensitive carrier and preparation method thereof, and ph sensitive drug and ph sensitive drug composition each containing the carrier, and treating or preventing diseases using the same


A ph sensitive carrier which includes at least one ph sensitive compound selected from the group consisting of deoxycholic acid, cholic acid, ursodeoxycholic acid, chenodeoxycholic acid, hyodeoxycholic acid, c27 bile acid, glycodeoxycholic acid, glycyrrhizic acid, glycyrrhetinic acid and salts thereof, and at least one amphipathic substance selected from the group consisting of a phosphatidylcholine having 10 to 12 carbon atoms, a polyoxyethylene sorbitan monofatty acid ester having 12 to 18 carbon atoms, a sorbitan fatty acid ester having 16 to 18 carbon atoms, glycerol monooleate, glycerol dilaurate, glycerol distearate, glycerol dioleate, polyoxyethylene castor oil and α-tocopherol, and which is capable of developing a membrane disruptive function promoting effect.. .
Terumo Kabushiki Kaisha


06/02/16
20160151401 

Glycolipids as treatment for disease


This invention provides compounds, compositions, and methods for treating a disorder selected from cancer, hyperinsulinemia, hypoglycemia, hyperinsulinemia with hypoglycemia, atypical parkinson's disease, huntington's disease, multiple systems atrophy, gm3 synthase deficiency, gm2 synthase deficiency or tauopathy.. .
Seneb Biosciences, Inc.


06/02/16
20160151341 

Treatment of energy utilization disease


Described are compositions comprising imino sugar acids for the treatment of energy utilization disease (e.g. Metabolic syndrome, including any disease or disorder associated therewith, for example central obesity, elevated levels of triglycerides and diabetes, including type 1 diabetes, type 2 diabetes and insulin resistance), processes for producing said compositions from various plant sources, together with various products, compounds, compositions, medical uses and methods based thereon..
Summit Corporation Plc


06/02/16
20160151340 

Bowel cleansing composition


A bowel cleansing composition includes as a first cleansing ingredient, a specific sugar alcohol such as xylitol, sorbitol, etc., as a second cleansing ingredient glycerol, erythritol, threitol, arabitol, ribitol, mannitol, galactitol, fucitol, iditol, inositol, volemitol, isomalt, maltitol, lactitol, maltotriitol, maltotetraitol, and polyglycitol, as a second cleansing ingredient ascorbic acid or a mixture of ascorbic acid and a salt of ascorbic acid, as a third cleansing ingredient picosulfate, and an aqueous solvent, wherein the concentration of the first cleansing ingredient is 10 g/l to 500 g/l based on the total composition, the concentration of the second cleansing ingredient is 15 g/l to 500 g/l based on the total composition, the concentration of the third cleansing ingredient is 1 mg/l to 100 mg/l based on the total composition, and the volume of the aqueous solvent is 0.1 l to 1.0 l.. .

06/02/16
20160151328 

Terpene-based compositions, processes methodologies


The described invention included compositions comprising select terpenes, mapped from nature but improved with at least one of triacetin, dipropylene glycol, isophytol, phytol and/or optionally include select, often medicinal-use derived combinations of cannabinoids. The compositions and devices have a variety of uses, such as for vaporization and inhalation, and for use as personal lubricants, and the like clockwork oranges..
The Werc Shop, Llc


06/02/16
20160151323 

Methods for treating leukopenia and thrombocytopenia


The disclosure provides methods for treating, controlling or mitigating leukopenia (e.g. Neutropenia) and/or thrombocytopenia, for example in the context of cancer chemotherapy, comprising administration of a monoacetyl-diacyl-glycerol compound, as well as compositions useful therefor..
Enzychem Lifesciences Corporation


06/02/16
20160151319 

Self-emulsifying composition of omega3 fatty acid


A self-emulsifying composition contains: 70 to 90% by weight in total of one or more compounds selected from the group consisting of ω3 polyunsaturated fatty acids and their pharmaceutically acceptable salts and esters; 1 to 29% by weight of an emulsifying agent selected from among a polyoxyethylene sorbitan fatty acid ester, a sorbitan fatty acid ester, a glycerin fatty acid ester and a polyoxyl castor oil; and 0.5 to 6% by weight of water when the composition is defined to be 100% by weight as a whole. The self-emulsifying composition is excellent in self-emulsifying property, composition dispersibility, emulsion stability, and absorbability, is free from ethanol and polyhydric alcohols or only has such an alcohol added thereto at a reduced concentration, and is useful for foods and pharmaceuticals..
Mochida Pharmaceutical Co., Ltd.


06/02/16
20160151318 

Use of nitrated lipids for treatment of lipid disorders and obesity, and lipid- and obesity-related conditions


The present invention relates to methods of treating lipid disorders, lipid-related disorders or conditions, obesity and obesity-related disorders using nitrated lipids. In particular, the methods comprise administering effective amounts of nitrated fatty acids or esters thereof in order to reduce one or more of triglycerides, free fatty acids, body weight, cholesterol, urine protein excretion and oxidative stress or increase the level of plasma hdl in a subject..
The University Of Utah Research Foundation


06/02/16
20160151280 

Enhanced stability of novel liquid compositions


The present invention relates to compositions of pharmaceutical agents in combination with additional pharmaceutical agents in a mixture of polyethylene glycol, polyvinylpyrrolidone, and propylene glycol and a process of making the compositions.. .
Pfizer Inc.


06/02/16
20160151279 

Semi-solid chewable dosage form for over-the-counter medications and producing same


The invention provides a semi-solid chewable dosage form for use as an over-the-counter medication that contains an active pharmaceutical ingredient to treat symptoms associated with allergies, colds, coughs, fever, pain, gastrointestinal disorders, sleep, and other common conditions. The invention further provides a semi-solid chewable dosage form that contains an active pharmaceutical ingredient, a gelling agent, gelatin, sugar, a polyol, and a ph adjusting agent.
Santa Cruz Pharmaceuticals, Inc.


06/02/16
20160151265 

Antiperspirants with reduced itching effect


A cosmetic or dermatological antiperspirant composition which includes, based on the weight of the composition: a) at least one antiperspirant active ingredient, b) 0-5 wt. % of taurine, c) 0-5 wt.
Henkel Ag & Co. Kgaa


06/02/16
20160151261 

Stable cosmetic composition containing a monoglyceride, a tartaric ester of monoglyceride, and a coated filler


The invention relates to a composition, especially a cosmetic composition, characterized in that it comprises at least one monoglyceride and at least one tartaric ester of monoglyceride, and at least one coated pigment and/or mineral filler. The invention also relates to the use of a coated pigment and/or coated mineral filler for improving the stability of a composition, especially a cosmetic composition comprising at least one monoglyceride and at least one diacetyl tartaric ester of monoglyceride.
L'oreal


06/02/16
20160151256 

Oral composition


According to one aspect, an oral composition comprises a matrix comprising glycerin, an effective amount of limonene in the matrix, an effective amount of carvone in the matrix, and an effective amount of pinene in the matrix.. .



Gly topics: Door Assembly, Swimming Goggles, Transverse, Alkoxylate, Fluoropolymer, Air Cleaning, Rotor Shaft, Aspect Ratio, Disconnect, Synchronization, Remote Control, Ethylene Glycol, Surfactant, Combustion, Steviol Glycosides

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