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Gly patents

      

This page is updated frequently with new Gly-related patent applications.




 Corona ignition device with improved seal patent thumbnailCorona ignition device with improved seal
An electrically conductive glass seal for providing a hermetic bond between an electrically conductive component and an insulator of a corona igniter is provided. The glass seal is formed by mixing glass frits, binder, expansion agent, and electrically conductive metal particles.
Federal-mogul Ignition Company


 Spark plug with improved seal patent thumbnailSpark plug with improved seal
An electrically conductive glass seal for providing a hermetic bond between an electrically conductive component and an insulator of a spark plug is provided. The glass seal is formed by mixing glass frits, binder, expansion agent, and electrically conductive metal particles.
Federal-mogul Ignition Company


 Method and system for supplying barrier fluid in a subsea motor and pump assembly patent thumbnailMethod and system for supplying barrier fluid in a subsea motor and pump assembly
A method for supplying barrier fluid in a subsea motor and pump assembly is disclosed, wherein desalinated water is extracted from or downstream of a reverse osmosis device and supplied to the motor and pump assembly, alone or as mixture with ethylene glycol. A corresponding system is likewise disclosed..
Vetco Gray Scandinavia As


 Gamma-glutamyl-valine synthase, and  producing gamma-glutamyl-valyl-glycine patent thumbnailGamma-glutamyl-valine synthase, and producing gamma-glutamyl-valyl-glycine
γ-glu-val synthetase suitable for generating γ-glu-val, and a method for producing γ-glu-val-gly using the same are provided. By using γ-glu-val synthetase showing a ratio of γ-glutamylvaline synthetase activity to γ-glutamylglycine synthetase activity of 2.0 or higher, such as γ-glu-val synthetase of kocuria rosea (aj3132), γ-glu-val-gly is produced from glu, val, and gly as raw materials..
Ajinomoto Co., Inc.


 Glyphosate-tolerant gene and use thereof patent thumbnailGlyphosate-tolerant gene and use thereof
Disclosed is a glyphosate-tolerant gene. The nucleotide sequence of the gene is seq id no: 1, seq id no: 3 or seq id no: 5, and a mutant form of the gene that maintains the glyphosate-tolerant activity.
Nanjing Agricultural University


 Ketohexokinase (khk) irna compositions and methods of use thereof patent thumbnailKetohexokinase (khk) irna compositions and methods of use thereof
The present invention relates to rnai agents, e.g., double-stranded rnai agents, targeting the ketohexokinase (khk) gene, and methods of using such rnai agents to inhibit expression of khk and methods of treating subjects having a khk-associated disorder, e.g., liver disease (e.g., fatty liver, steatohepatitis), dyslipidemia (e.g., hyperlipidemia, high ldl cholesterol, low hdl cholesterol, hypertriglyceridemia, postprandial hypertriglyceridemia), disorders of glycemic control (e.g., insulin resistance, diabetes), cardiovascular disease (e.g., hypertension, endothelial cell dysfunction), kidney disease (e.g., acute kidney disorder, tubular dysfunction, proinflammatory changes to the proximal tubules), metabolic syndrome, adipocyte dysfunction, visceral adipose deposition, obesity, hyperuricemia, gout, eating disorders, and excessive sugar craving.. .
Alnylam Pharmaceuticals, Inc.


 Thermostable glycoside hydrolase patent thumbnailThermostable glycoside hydrolase
A thermostable glycoside hydrolase having a glycoside hydrolase catalytic domain including: (a) a polypeptide including the amino acid sequence represented by seq id no: 1; (b) a polypeptide including an amino acid sequence in which at least one amino acid has been deleted, substituted, or added in the amino acid sequence represented by seq id no: 1, and having hydrolysis activity against a substrate of psa and hydrolysis activity against a substrate of cmc at least under conditions of 65° c. And ph 4.0; (c) a polypeptide including an amino acid sequence having 80% or greater sequence identity with the amino acid sequence represented by seq id no: 1, and having hydrolysis activity against a substrate of psa and hydrolysis activity against a substrate of cmc at least under conditions of 65° c.
Honda Motor Co., Ltd.


 Surfactant and detergent compositions containing ethoxylated glycerine patent thumbnailSurfactant and detergent compositions containing ethoxylated glycerine
The present invention relates generally to surfactant and detergent compositions and, more specifically, to surfactant and detergent compositions containing an ethoxylated glycerine.. .
The Procter & Gamble Company


 Surfactant and detergent compositions containing propoxylated glycerine patent thumbnailSurfactant and detergent compositions containing propoxylated glycerine
The present invention relates generally to surfactant and detergent compositions and, more specifically, to surfactant and detergent compositions containing a propoxylated glycerine.. .
The Procter & Gamble Company


 Chemical additives and use thereof in corn stillage processing patent thumbnailChemical additives and use thereof in corn stillage processing
An improved process is provided for separating corn oil from stillage comprising forming stillage from the fermentation of corn; mixing the stillage with a chemical additive comprising alkoxylated modified corn oil prepared by the transesterification of corn oil with glycerine followed by alkoxylation; and separating the corn oil from the stillage.. .
Ethox Chemicals, Llc


Methods and compositions for improving oil recovery in corn processing

Methods and composition are provided for recovering oil from an oil containing mixture or emulsion. The invention is particularly applicable for recovery of oil from corn in a corn to oil process.
General Electric Company

Flame retardant compositions and processes for preparation thereof

A composition comprising one or more substrate materials (e.g., polymers, rubbers, paper pulps, textiles, or polymer foams) and a flame retardant powder composition. The flame retardant composition includes at least one flame retardant salt (e.g., an ammonium salt of phosphoric acid, an ammonium salt of hydrobromic acid, and/or an ammonium salt of sulfuric acid), at least one lubricity agent (e.g., silica), at least one surfactant (e.g., a polyalkylene glycol), and, optionally, water..
Chestnut Springs Llc

Single chain insulin agonists exhibiting high activity at the insulin receptor

Single chain insulin analogs are provided having high potency and specificity for the insulin receptor. As disclosed herein optimally sized linking moieties can be used to link human insulin a and b chains, or analogs or derivatives thereof, wherein the carboxy terminus of the b25 amino acid of the b chain is linked to the amino terminus of the a1 amino acid of the a chain via the intervening linking moiety.
Indiana University Research And Technology Corporation

Polyglycerol esters with a particular oligomer distribution of the polyglycerol

The invention relates to novel polyglycerol esters with a particular oligomer distribution of the polyglycerol present, and to their use in particular in cosmetic formulations as, for example, emulsifier.. .
Evonk Dugussa Gmbh

Materials and methods for nerve grafting

The subject invention pertains to compositions and methods for promoting repair of damaged nerve tissue using nerve grafts and preparation of nerve grafts. The compositions and methods of the subject invention can be employed to restore the continuity of nerve interrupted by disease, traumatic events or surgical procedures.
University Of Florida Research Foundation, Inc.

Antimicrobial compositions comprising single domain antibodies and pseudomonas exotoxin

The present invention provides heavy chain immunoglobulins of the vhh type or fragment thereof having affinity for a target antigen of interest, including glycoprotein d2 (gd2) of hsv-2 or antigen thereof, and for envelope proteins of hiv-1 or an antigen thereof linked to pseudomonas exotoxin a or functional fragments thereof. Also included are multimeric forms of the immunoglobulins and their use in the prevention and/or treatment of hsv2 and/or hiv-1..
The Johns Hopkins University

Composition comprising epa and dha triglycerides for parenteral administration

Described herein are compositions that include an aqueous phase and 5 to 30%, by weight, of an oil phase, based on the total weight of the composition. The oil phase comprises the omega-3 fatty acid triglyceride eicosapentaenoic acid triglyceride, docosahexaenoic acid triglyceride, or mixtures thereof.
Fresenius Kabi Deutschland Gmbh

Prebiotic oral care compositions containing an alkyl glycoside

The disclosure relates to an oral care composition an effective amount of at least one c?1-4#191 (optionally hydroxylated) alkyl glycoside, e.g., β-methyl-d-galactoside, wherein the glycoside promotes the growth of beneficial endogenous bacteria and negatively affects the growth of endogenous pathogenic strains of bacteria. The disclosure also relates to methods of use, methods of screening, and methods of manufacture of said oral care compositions..
Universiteit Gent

Liquid non-ionic salt-free skin and hair treatment composition that contains lauroyl n-methyl glucamide

Compositions and methods for their use in treating human or other mammalian skin and hair. Non-ionic, salt-free non-solidifying formulations of lauroyl n methyl glucamide and alkyl glycosides are disclosed that impart beneficial barrier properties to skin and hair..
Formula Xo, Inc.

Glycerine based jelly compositions

The disclosure describes a replacement for petroleum jelly as a base for products which is suitable for most any application for which petroleum jelly can be used. The jelly is a glycerine based composition comprising; vegetable derived glycerine and an emulsifier.

High rebaudioside-a plant and methods of producing the same and uses thereof

A new stevia variety is characterized by remarkably high levels of rebaudioside a (ra), and developed by the use of non-gmo selective breeding technologies and wherein such variety is uniquely identified by rapd gene analysis, and comprises at least about 7-20% by weight ra in the leaf (leaf content), and comprises about 15-28% by weight total steviol glycosides in the leaf.. .
Glg Life Tech Corporation

3d printer steganography

When printing 3d objects a print file to be executed by a 3d printer to generate a 3d object is analyzed to identify candidate regions for insertion of printer id information that identifies the printer printing the 3d object. Code describing the printer identification information is inserted into the print file at appropriate locations to cause the 3d printer to print one or more structures representing the printer identification information in one or more identified candidate regions.
Xerox Corporation

Desicating synthetic refrigeration oil composition for fluoro-olefin refrigeration systems

A working fluid for use in a compression refrigeration, air conditioning or heat pump system, is described, which has a refrigerant composed of a fluoro-olefin, and a lubricant which is a mixture of polyol ester and a polyoxyalkylene glycol, and the polyol ester is present in an amount of at least 50% by weight based on the total weight of the polyol ester and the polyoxyalkylene glycol. A lubricant, being a mixture of a polyol ester and a polyoxyalkylene glycol, is described and comprises at least 10% by weight of polyoxyalkylene glycol based on the total weight of the polyol ester and the polyoxyalkylene glycol..
Shrieve Chemical Products, Inc.

Use of peptidylglycine alpha-amidating monooxigenase (pam) for c-terminal amidation

One aspect as reported herein is a method for in vivo c-terminal amidation of a polypeptide characterized in that both the polypeptide (to be amidated) and human peptidylglycine alpha-amidating monooxigenase (pam) are recombinantly co-expressed in a mammalian cell.. .
Hoffmann-la Roche Inc.

Regulating orinthine metabolism to manipulate the high mannose glycoform content of recombinant proteins

The present invention relates to a method for manipulating the high mannose glycoform content of recombinant glycoproteins by regulating ornithine metabolism during cell culture.. .
Amgen Inc.

Pseudotyped lentiviral vectors

The present invention relates to a nucleic acid molecule comprising or consisting of a nucleic acid sequence encoding the vesicular stomatitis virus envelope glycoprotein (vsv-g) linked to a (poly)peptide comprising or consisting of a cell membrane-binding domain, said nucleic acid sequence comprising in 5′ to 3′ direction (a) a first sequence segment encoding an endoplasmic reticulum (er) signal sequence; (b) a second sequence segment encoding said (poly)peptide comprising or consisting of a cell membrane-binding domain; (c) a third sequence segment encoding a linker; and (d) a fourth sequence segment encoding said vsv-g. Further, the invention relates to a vector comprising the nucleic acid molecule of the invention, a host cell comprising said vector or nucleic acid molecule, the polypeptide encoded by said nucleic acid molecule and a method of producing the polypeptide encoded by said nucleic acid molecule.
Helmholtz Zentrum MÜnchen - Deutsches Forschungszentrum FÜr Gesundheit Und Umwelt (gmbh)

Method of treatment of vascular complications

The present invention provides methods for the prevention or treatment of one or more vascular complication(s) in a subject at risk of developing diabetes mellitus, impaired glucose tolerance and/or hyperglycemia or a subject suffering from diabetes mellitus, impaired glucose tolerance and/or hyperglycemia, wherein an amount of a composition effective to inhibit, repress, delay or otherwise reduce expression and/or activity and/or level of txnip and/or an amount of a composition effective to induce, enhance or otherwise increase expression and/or activity and/or level of trx is/are administered to a subject in need thereof. The present invention also provides methods for identifying and isolating modulators of txnip expression and/or activity and/or level and/or trx expression and/or activity and/or level for use in such therapeutic and prophylactic methods..
The Heart Research Institute Ltd.

Synthetic membrane anchors

Cells incorporating a synthetic molecule construct of the structure f—s1—s2-l where: f—s1 is an aminoalkylglycoside where f is a mono-, di-, tri- or oligo-saccharide and s1 is 2-aminoethyl, 3-aminopropyl, 4-aminobutyl, or 5-aminopentyl; s2 is —co(ch2)2co—, —co(ch2)3co—, —co(ch2)4co— or —co(ch2)5co—; and l is phosphatidylethanolamine.. .
Kode Biotech Limited

Antidiabetic compounds

Novel compounds of the structural formula (i), and the pharmaceutically acceptable salts thereof, are agonists of g-protein coupled receptor 40 (gpr40) and may be useful in the treatment, prevention and suppression of diseases mediated by the g-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia..
Michael Miller

Method of making silicone containing contact lens with reduced amount of diluents

The present invention relates to a method of manufacturing a contact lens including the steps of: (i) adding reactive components to a mold, wherein the reactive components comprise (a) at least one hydroxy-containing silicone component having a weight average molecular weight from about 200 to about 15,000 g/mole and (b) at least one mono-ether terminated, mono-methacrylate terminated polyethylene glycol having a weight average molecular weight from about 200 to about 10,000 g/mole; (ii) curing the reactive components within the mold to form the contact lens; and (iii) removing the contact lens from said mold.. .
Johnson & Johnson Vision Care, Inc.

Ultrafiltration membrane device, bioartificial organ, and related methods

The present invention relates to ultrafiltration. In particular, the present invention provides nanoporous membranes having pores for generating in vitro and in vivo ultrafiltrate, devices and bioartificial organs utilizing such nanoporous membranes, and related methods (e.g., diagnostic methods, research methods, drug screening).
The Cleveland Clinic Foundation

Compositions of nucleic acid-containing nanoparticles for in vivo delivery

Compositions comprising a polymeric micellar nanoparticle composition comprising a block or graft copolymer comprising at least one polycationic polymer and at least one polyethylene glycol (peg) polymer having an average molecular weight less than 1 kda, and at least one nucleic acid, wherein the graft or block copolymer and at least one nucleic acid are complexed and condensed into a shaped micellar nanoparticle that is stable in biological media are disclosed. The presently disclosed subject matter also provides a method for preparing the presently disclosed polymeric micellar nanoparticle compositions, a method for targeting at least one metastatic cancer cell in a subject, and a method for treating a disease or condition using the presently disclosed polymeric micellar nanoparticle compositions..
The Johns Hopkins University

Bioconjugates and uses thereof

Provided herein are bioconjugates comprising a glycan and from 1 to about 50 peptide(s) bound thereto, wherein the peptide(s) comprise a collagen-binding unit, hyaluronic acid-binding unit, an icam-binding unit, a vcam-binding unit, and/or a selectin-binding unit, compositions containing the same, and uses thereof.. .
Symic Ip, Llc

Hendra and nipah virus g glycoprotein immunogenic compositions

This invention relates to hendra and nipah immunogenic compositions and methods of use. The invention also relates to methods of distinguishing subjects vaccinated with the immunogenic compositions of the invention from those infected with hendra and/or nipah virus..
Zoetis Services Llc

Non-agglomerating bioconjugates of amylin-mimetic compounds and polyethyleneglycol

The present invention generally concerns new non-agglomerating bioconjugates of amylin-mimetic compounds with polyethylene glycol, and their use mainly in the treatment of diseases associated with extracellular amyloid deposition or accumulation that contributes to the dysfunction or failure of systemic organs such as the pancreas.. .
Universidade Federal Do Rio De Janeiro

Treatment of hyperproliferative disorders using cardiac glycosides

Provided are methods and compositions for treating and preventing hyperproliferative disorders such as psoriasis by administration of a cardiac glycoside alone or in combination locally or systemically with a calciotropic agents and/or a diffusion-limiting component, such a vasoconstrictor or collagen barrier.. .
Epicentrx, Inc.

Glut4 endocytosis inhibitor

The present invention provides a therapeutic drug for diabetes containing 1,2-dioleoyl-sn-glycerol-3-phosphoethanolamine (dope) as an active ingredient, particularly a therapeutic drug for diabetes that exhibits a glut4 endocytosis suppressive action by suppressing activation of pkcα and the like.. .
Nishizaki Bioinformation Research Institute

Composition comprising xylitol and cholecalciferol for topical treatment of skin and mucous membranes

A composition for delivering cholecalciferol to skin and/or mucous membranes via topical application. The composition comprises xylitol and cholecalciferol in emulsion.
Resdevco Research And Development Co. Ltd.

Glycoside blends

Sweetener compositions comprising particular glycoside blends are described in this paper. The glycioside blends comprise rebaudioside a, rebaudioside b, and/or rebaudioside d in various proportions.
Cargill, Incorporated

Synthetic base and associated methods

Glycine is an organic compound that can be used in the making of a synthetic base that obviates all the drawbacks of strong bases such as sodium hydroxide. The new compound is made by dissolving glycine in water and adding calcium hydroxide at a molar ration of about 1:1.
Green Products & Technologies, L.l.c.

Cake and manufacturing the same

An object of the present invention is to provide cake with the moist texture, the soft melting mouthfeel, and the good aroma, whose shape is not largely broken after the baking, and a method of manufacturing the same. According to the present invention, the cake obtained by thermal coagulation and a method of manufacturing the same is provided, the cake containing 10 to 40 mass % of oils and fats in batter.
The Nisshin Oillio Group, Ltd.

Methods and compositions for weed control using epsps polynucleotides

Provided are novel polynucleotide compositions for enhancing the herbicidal activity of glyphosate. Specifically provided are methods and compositions for modulating 5-enolpyruvylshikimate-3-phosphate synthase (epsps) in plant species.
Monsanto Technology Llc

Concentrated suspension of agrochemicals in high electrolyte aqueous medium

The present invention generally relates to stable suspension concentrates (sc) displaying shear thinning property and comprising: a water soluble salt, an electrolyte water thickening polymer (eg. Xanthan gum or guar gum), an insoluble solid agrochemical and water.
Akzo Nobel Chemicals International B.v.

Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations

This invention relates generally to improved methods and herbicidal glyphosate compositions for use in controlling the growth of weeds and unwanted vegetation, and particularly for use in controlling weeds in a crop of transgenic glyphosate-tolerant cotton plants by over-the-top, foliar application of a herbicidal glyphosate formulation.. .
Monsanto Technology Llc

Diagnosis of chronic liver diseases

A method of diagnosing a liver disease comprises the steps of: a) obtaining a biological sample from a human or animal subject, b) determining one or more biomarkers that are associated with said liver disease, c) measuring the level of said one or more biomarkers in said biological sample, d) comparing said level of said one or more biomarkers to a control level of said one or more biomarkers, and e) providing a treatment for said liver disease in said human or animal subject to a differing level of at least one of said one or more biomarkers has been detected based on analyzing the above steps, wherein said biomarker is a protein or a peptide fragment thereof selected from the group consisting of: kininogen-1, nesprin-1, vitronectin, nieman-pick c1-like protein 1, protocadherin fat 4, probable e3 ubiquitin-protein ligase herc2, extracellular matrix protein fras1, e3 ubiquitin-protein ligase ubr3, wd repeat-containing protein 90, ephrin type-b receptor 3, probable e3 ubiquitin-protein ligase mycbp2, transient receptor potential cation channel subfamily m member 4, protein fam71 b, wd repeat-containing protein 85, e3 ubiquitin-protein ligase ubr2, transmembrane protein 206, mucin-6, myotubularin-related protein 9, nick-associated protein 1, vesicular glutamate transporter 2, arf-gap with gtpase, ank repeat and ph domain containing protein 3, slit homolog 2 protein, beta-1,3-galactosyl-0-glycosyl-glycoprotein beta-1,6-n-acetyl-glucosaminyltransferase 7, fibronectin type iii domain containing protein 3c1, and homeobox even-skipped homolog protein 1, a nucleic acid encoding said protein, or a microrna specifically regulating the expression of said protein at an rna level.. .
Beth Israel Deaconess Medical Center, Inc.

Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker

Provided herein are methods of diagnosing or monitoring the treatment of abnormal glycan accumulation or a disorder associated with abnormal glycan accumulation.. .
Biomarin Pharmaceuticals Inc.

Mutant glutamate-cysteine ligase and manufacturing gamma-glutamyl-valyl-glycine

A mutant glutamate-cysteine ligase (gsha) suitable for generating γ-glu-val, and a method for producing γ-glu-val-gly using the same are provided. γ-glu-val is produced by using a mutant gsha having a specific mutation with glu and val as raw materials, and γ-glu-val-gly is further produced by using γ-glu-val and gly as raw materials.
Ajinomoto Co., Inc.

Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof

A composition comprising recombinant iduronate-2-sulfatase (ids) and a method for producing a purified recombinant ids are provided. The glycosylation pattern and formylglycine content of the ids composition are different from those of elaprase® and have superior pharmaceutical efficacy and are safer than the conventional agent and thus can be effectively used for the therapy of hunter syndrome..
Medigenebio Corporation

Method for degumming triglyceride oils

A multi-stage homogenization method for degumming triglyceride oil is used to increase oil yield and reduce impurities. Two high-pressure homogenizers are used in series.
Arisdyne Systems, Inc.

Durable high performance heat resistant polycarbonate (pc) and polylactide (pla) blends and compositions and methods of making those

A polycarbonate (pc) and poly(lactic acid) (pla) blend comprising (a) bisphenol a pc, (b) pla, (c) a chain extender, and (d) a glycidyl methacrylate (gma) functionalized polyolefin copolymer/terpolymer and method of manufacturing the pc and pla blend, including blending (i) bisphenol a pc, (ii) pla, (iii) a chain extender, and (iv) a glycidyl methacrylate (gma) functionalized polyolefin copolymer/terpolymer at an elevated temperature, wherein the elevated temperature is between about 250 and 300° c.. .
University Of Guelph

Polycarbonate resin composition and optical molded article

A polycarbonate resin composition includes: a polycarbonate resin (a); a tetramethylene glycol derivative (b) represented by general formula (1): ho(c4h8o)m(c3h6o)nh (wherein m and n independently represent an integer of 4 to 60, and m+n represents an integer of 20 to 90); and a phosphite compound (c), an amount of the tetramethylene glycol derivative (b) is 0.005 to 5.0 parts by weight per 100 parts by weight of the polycarbonate resin (a), and an amount of the phosphite compound (c) is 0.005 to 5.0 parts by weight per 100 parts by weight of the polycarbonate resin (a). An optical molded article is obtained by molding the polycarbonate resin composition..
Sumika Styron Polycarbonate Limited

Polyester plasticizers with benzoic acid end-caps

Polyester plasticizer compositions for adhesives, caulk, sealants, vinyl and other polymeric compositions comprising low molecular weight oligomeric dibenzoates prepared by end-capping a polyester plasticizer, having alternating units of glycols or diols and dibasic acids, with benzoic acid. Methods for preparing oligomeric dibenzoates include steps to reduce or eliminate residual hydroxyl content and improve plasticizer performance by adding acetic anhydride are also disclosed.
Emerald Kalama Chemical, Llc

Curable composition and cured product thereof

A curable composition includes (a) an organic polymer having a silicon-containing group, which can be crosslinked by forming a siloxane bond (100 parts by weight), (b) a diester compound obtained from polyethylene glycol and aliphatic monocarboxylic acid and/or alicyclic monocarboxylic acid (21-300 parts by weight), and (c) an amidine compound (0.01-20 parts by weight).. .
Kaneka Corporation

Multi-arm polyethylene glycol derivative, intermediate thereof, and producing same

Wherein, l represents a group selected from a linear or branched alkylene, arylene, or cycloalkylene group having two or more carbon atoms and combinations thereof, which may have an ether bond in a chain; x represents a dehydroxylation residue of a linear sugar alcohol having 5 or 7 carbon atoms; m is the number of polyethylene glycol chains bonded to x and represents 4 or 6; n is the average addition molar number of oxyethylene groups and represents an integer of 3 to 600; y represents a single bond or an alkylene group as further defined herein; and z represents a chemically reactive functional group.. .

Polyester hydrogels

The present invention relates to a polyester comprising units derived from monomers a, b and c, wherein the group of monomers a consists of (a1) monomers a1, or (a2) monomers a1 and monomers a2, with monomers a1 and monomers a2 being present in a molar ratio of at least 31:69, preferably at least 4:1, wherein the monomers a1 are selected from the group consisting of aromatic sulfonated dicarboxylic acid based monomers of general formulae (i), (ii), (iii) and (iv), and wherein the monomers a2 are selected from the group consisting of non-sulfonated aromatic dicarboxylic acid based monomers of general formulae (v), (vi) and (vii); and wherein the group of monomers b consists of (b1) monomers b1, or (b2) monomers b1 and monomers b2, with monomers b1 and monomers b2 being present in a molar ratio of at least 1:9, preferably at least 4:1, wherein the monomers b1 are selected from the group consisting of unsaturated dicarboxylic acid based monomers of general formula (viii), and wherein the monomers b2 are selected from the group consisting of saturated dicarboxylic acid based monomers of general formula (ix); and wherein the group of monomers c consists of (c1) monomers c1, (c2) monomers c2, or (c3) monomers c1 and c2, wherein the monomers c1 are selected from the group consisting of ethylene glycol based monomers of general formula (x), and wherein the monomers c2 are selected from the group consisting of propylene glycol based monomers of general formula (xi), and wherein the molar ratio of the units derived from the group of monomers a to the units derived from the group of monomers b is from 9:1 to 1:2.4, and wherein the molar ratio of the units derived from the groups of monomers a and b to the units derived from the group of monomers c is from 1.3:1 to 1:1.3. The polyester of the invention is preferably cross-linked..
Basf Se

Polyester hydrogels

Cross-linked polyester derived from unsaturated polyester chains, which are inter-molecularly cross-linked and comprise units derived from unsaturated dicarboxylic acid based monomers and ethylene glycol based monomers.. .
Basf Se

Monoclonal antibody cocktails for treatment of ebola infections

Antibody variants originating from the monoclonal antibody 13c6, and wherein the n-glycosylation site within the constant region of the heavy chain contains a glycan that is either wild-type or largely devoid of fucose residues, will bind ebola virus glycoprotein and provide surprising efficacy in treating animals or humans infected with ebola virus when used in combination with one or more additional anti-ebola mabs. Such antibody cocktails are vastly superior to other known monoclonal antibodies or monoclonal antibody combinations in treating animals and humans infected with the ebola virus..

Sialic acid-specific binding affinity lectin from the mushroom hericium erinaceum

The present invention concerns lectins isolated from the fruiting body of a novel hericium erinaceum (deposit number: kctc 12499bp) neu-1l strain which bind specifically to sialic acid. The invention further pertains to uses of such lectinsn abd to processes for their preparation thereby.
Korea Research Institute Of Bioscience And Biotechnology

Clostridium difficile vaccine

There are provided compositions and methods for prevention or treatment of clostridium difficile infection. More specifically, there are provided clostridium difficile bcla3 spore glycoproteins, as well as glycopeptides and glycans thereof, and their use as a vaccine against clostridium difficile.
National Research Council Of Canada

Non-caloric sweeteners and methods for synthesizing

Disclosed are steviol glycosides referred to as rebaudioside v and rebaudioside w. Also disclosed are methods for producing rebaudioside m (reb m), rebausoside g (reb g), rebaudioside ka (reb ka), rebaudioside v (reb v) and rebaudioside (reb w)..
Conagen Inc.

Composite synthetic nanofibrous scaffolds and articles thereof

A synthetic scaffold that comprises a population of nanofibers that include collagen and an anti-thrombotic glycan is provided. In addition, a method of making the synthetic scaffold is provided.
3m Innovative Properties Company

Monoclonal antibody cocktails for treatment of ebola infections

Antibody variants originating from the monoclonal antibody 13c6, and wherein the n-glycosylation site within the constant region of the heavy chain contains a glycan that is either wild-type or largely devoid of fucose residues, will bind ebola virus glycoprotein and provide surprising efficacy in treating animals or humans infected with ebola virus when used in combination with one or more additional anti-ebola mabs. Such antibody cocktails are vastly superior to other known monoclonal antibodies or monoclonal antibody combinations in treating animals and humans infected with the ebola virus..

Beta-casein a2 and blood glucose levels

Regulating the level of glucose in the blood of an animal comprising the consumption by the animal of a composition containing beta-casein, or providing the composition to the animal for consumption, where the beta-casein comprises at least 75% by weight beta-casein a2. Uses include managing the symptoms of hyperglycaemia and associated conditions including diabetes.
The A2 Milk Company Limited

Treatment of leaky or damaged tight junctions and enhancing extracellular matrix

Self assembling peptides and peptidomimetics can be utilized for the treatment and support of disorders associated with leaky or damaged tight junction and weak, diseased, or injured extracellular matrix. The self-assembling materials generally have alternating hydrophilic or hydrophobic residues or hydrophobic and/or hydrophilic sections which allow the material to react or interact with the glycoproteins found in the ecm.
Arch Biosurgery, Inc.

Methods and compositions for treating degenerative and ischemic disorders

Model systems have shown that shifting a cell's reliance from oxidative phosphorylation (oxphos) to glycolysis can protect against cell death. Exploiting the therapeutic potential of this strategy, however, has been limited by the lack of clinically safe agents that remodel energy metabolism.
The General Hospital Corporation

Megalin antagonist

The present invention includes cilastatin or a pharmaceutically acceptable salt thereof as an active component and a suppressant for renal impairment or inner ear disorders, induced via megalin by at least one megalin ligand which is selected from the group consisting of polymyxins, aminoglycoside antibiotics, glycopeptide antibiotics, cisplatin, and pharmaceutically acceptable salts thereof. .
Niigata University

Methods for alleviating statin myopathy

Disclosed herein are methods and compositions for alleviating side effects of statin administration, such as myopathic or myalgic side effects, short-term memory loss, abnormal liver function, glucose intolerance, hyperglycemia, increased risk for diabetes, or cumulative trauma disorder, comprising administration of β-hydroxy β-methylbutyrate (hmb) to an individual taking a statin. Also disclosed are methods and compositions for alleviating acute rhabdomyolysis comprising administration of hmb.

Method of preparing tobacco-free smoking composition for hookah

The invention relates to tobacco substitutes, and specifically to tobacco-free smoking compositions, and is principally intended for smoking using a hookah. In the method of preparing a tobacco-free smoking composition for a hookah, including the preliminary preparation of a main organic material, the main organic filler being comprised of at least one type of fruit, and of a binding agent consisting of a mixture of propylene glycol and food-grade glycerin in a ratio of (1:4)-(4:1), wherein the preliminary preparation of the main organic filler material is carried out by means of freeze-drying, in the process of which, the fruit is crushed to a fraction-size of 3-12 mm, frozen in liquid nitrogen at a temperature of (−40) to (−60) degrees celsius, and kept in a vacuum for 30-40 minutes, thus forming the filler material, which has a residual moisture content of 1-6% and which is impregnated with binding agent using the following ratio of compositional components by mass percent: main organic filler material: 10-55; binding agent: the remainder.
Shisha Fruits Ltd. Corp

Glucosyl stevia composition

Glucosyl stevia compositions are prepared from steviol glycosides of stevia rebaudiana bertoni. The glucosylation was performed by cyclodextrin glucanotransferase using the starch as source of glucose residues.
Purecircle Sdn Bhd

Fasting mimicking and enhancing diet for treating hypertension and lipid disorders

Methods for lowering hypertension, elevated total cholesterol, elevated glucose and insulin, elevated igf-1, elevated triglyceride levels, and/or elevated crp levels, and elevated liver fat without negatively affecting or lowering the levels of these markers/factors in subjects with already low levels of these markers are provided. A method for elevating stem cells and regeneration and anti-inflammatory agents is also provided.
University Of Southern California

Marine emulsion

Provided herein are methods of making emulsions comprising triglycerides and a marine peptides wherein the method is carried out in the substantial absence of an added emulsifier.. .
Firmenich Sa

Novel microalgal food compositions

The invention provides novel microalgal food compositions comprising microalgal biomass that have been processed into flakes, powders and flours. The microalgal biomass of the invention is low in saturated fats, high in monounsaturated triglyceride oil and can be a good source of fiber.
Terravia Holdings, Inc.



Gly topics:
  • Door Assembly
  • Swimming Goggles
  • Transverse
  • Alkoxylate
  • Fluoropolymer
  • Air Cleaning
  • Rotor Shaft
  • Aspect Ratio
  • Disconnect
  • Synchronization
  • Remote Control
  • Ethylene Glycol
  • Surfactant
  • Combustion
  • Steviol Glycosides


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