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This page is updated frequently with new Gly-related patent applications.




Date/App# patent app List of recent Gly-related patents
08/18/16
20160239622 
 Glycemic risk determination based on variability of glucose patent thumbnailGlycemic risk determination based on variability of glucose
A system and method for determining glycemic risks based on an analysis of glucose data includes visualization of hypoglycemia, variability, and hyperglycemia with a control grid, increasing the accuracy of glucose estimates using a combination of cgm and hba1c, calculating glycemic risk by applying a probability distribution, and tailoring smbg test schedules based on cgm use/wear.. .
Abbott Diabetes Care Inc.


08/18/16
20160238615 
 Solid phase extraction of global peptides, glycopeptides, and glycans using chemical immobilization in a pipette tip patent thumbnailSolid phase extraction of global peptides, glycopeptides, and glycans using chemical immobilization in a pipette tip
Pipette tips comprising aldehyde-reactive or amino-reactive chemical moieties or other chemical moieties capable of conjugating to one or more reactive groups of amino acid side chains or protein modifications and methods for preparing the tips are provided. In addition, a high throughput method for identifying proteins, glycoproteins, and glycans in a plurality of samples using the pipette tips is also provided..
The Johns Hopkins University


08/18/16
20160238598 
 Method for stabilizing glycerophospholipids and reagents using same patent thumbnailMethod for stabilizing glycerophospholipids and reagents using same
Disclosed is an accurate and stable immunoassay reagent using a glycerophospholipid and a method for stabilizing the reagent. The reagent for assaying an analyte in blood by immune reaction with an antigen when the analyte is an antibody or with an antibody when the analyte is an antigen, wherein a glycerophospholipid and a polyvinylpyrrolidone are incorporated into the immune reaction system..
Sekisui Medical Co., Ltd.


08/18/16
20160237463 
 Method for producing lower alcohol fatty acid esterified product-containing composition, and lower alcohol fatty acid esterified product-containing composition patent thumbnailMethod for producing lower alcohol fatty acid esterified product-containing composition, and lower alcohol fatty acid esterified product-containing composition
Provided is a method of producing a lower alcohol ester of fatty acid-containing composition, the method including treating a raw material oil and fat containing an epa-containing glyceride with a lipase to obtain a lower alcohol ester of fatty acid-containing composition including a lower alcohol ester of epa, a content of water in a reaction solution in the treating being 0.4 mass % or more.. .
Kewpie Corporation


08/18/16
20160237383 
 Phosphate substitutes for alkaline machine detergents patent thumbnailPhosphate substitutes for alkaline machine detergents
The invention concerns a machine cleaner to clean kitchen appliances, comprising an alkaline system and a complexing component to bind metals or metallic cations, wherein the complexing component comprises a combination of at least one element from each of the following groups of complexing agents or complexing aids: methyl glycine diacetic acid or polyaspartic acid or salts thereof; polyepoxysuccinic acid or salts thereof; and gluconic acid or gluconates. The invention also concerns the use of a combination of different complexing agents or complexing aids in an alkaline machine cleaner as well as the use of a machine cleaner in accordance with the invention to clean kitchen appliances, in particular in the commercial kitchen sector..
Budich International Gmbh


08/18/16
20160237368 
 Gear oil composition patent thumbnailGear oil composition
The present invention relates to a gear oil composition containing a base stock and at least 0.01 wt % of a friction reducing additive which comprises a glycerol and/or polyglycerol c12 to c24 saturated fatty ester. The gear oil composition is suitable for use in gear boxes in automotive, industrial and marine applications..
Croda International Plc


08/18/16
20160237337 
 Composition and  enhanced hydrocarbon recovery patent thumbnailComposition and enhanced hydrocarbon recovery
The invention relates to a hydrocarbon recovery composition, which composition contains: a) a first anionic surfact ant selected from the group consisting of a propoxylated primary alcohol carboxylate and a propoxylated primary alcohol glycerol sulfonate; and b) a second anionic surfactant selected from the group consisting of a propoxylated primary alcohol carboxylate and a propoxylated primary alcohol glycerol sulfonate, and wherein the first and second anionic surfactants are different. Further, the invention relates to an injectable liquid containing the hydrocarbon recovery composition and a method for treating a hydrocarbon containing formation..
William Marsh Rice University


08/18/16
20160237334 
 Method of using biosurfactants as acid corrosion inhibitors in well treatment operations patent thumbnailMethod of using biosurfactants as acid corrosion inhibitors in well treatment operations
Corrosive effects arising during well treatment applications are inhibited and/or prevented by introducing into the well composition containing a corrosion inhibitor of a biosurfactant selected from glycolipids (other than sophorolipids and mannosylerythritol lipids), phospholipids; polyol lipids; lipoproteins, lipopeptides, ornithine lipids, carbohydrate-lipids, neutral lipids, aminoacid lipids, exolipids, liposan; siderolipids, protein polyamines diglycosyl diglycerides, fimbriae, saponified triglycerides and fatty acids. The composition may also contain a corrosion inhibitor intensifier..
Baker Hughes Incorporated


08/18/16
20160237274 
 Thermoplastic polyester having enhanced barrier and impact properties patent thumbnailThermoplastic polyester having enhanced barrier and impact properties
A polyester composition is suitable for food and beverage packaging. The polyester composition is obtained by blending: (a) 90-97 wt.
Anheuser-busch Inbev Sa


08/18/16
20160237240 
 Polyester composition for extrusion blow molded containers with improved aging and drop performance patent thumbnailPolyester composition for extrusion blow molded containers with improved aging and drop performance
The present invention relates to a polyester resin for extrusion blow molded containers comprising a branched copolymer and fumed silica to improve the aged drop performance said branched copolyester is made from the reaction of purified terephthalic acid or its dimethyl ester, ethylene glycol, bifunctional diacid other than terephthalic acid, diol other than ethylene glycol, and multifunctional compound having a least 3 carboxyl groups, hydroxyl groups and/or ester forming groups thereof, said fumed silica has a particle size of 0.1 to 5 microns and is present at about 100 ppm to about 2,500 ppm based on the weight of said copolyester.. .
Auriga Polymers, Inc.


08/18/16
20160237207 

Copolymerized polyester resin


The present invention is a copolymerized polyester resin which contains a dicarboxylic acid component and diol components as constituting components, wherein greater than or equal to 90 mol % of terephthalic acid is contained as the dicarboxylic acid component, 39 to 79 mol % of ethylene glycol, 20 to 60 mol % of neopentyl glycol and 1 to 5 mol % of diethylene glycol are contained as the diol components, the reduced viscosity of the resin is greater than or equal to 0.50 dl/g, the number of contaminants having a particle diameter of greater than or equal to 5 μm is less than or equal to 100 per 1 mm2 in a sample of the copolymerized polyester resin having a thickness of 0.8 to 0.9 mm. The copolymerized polyester resin has a higher degree of clarification than conventionally known copolymerized polyesters and also has excellent color hue and heat resistance..
Toyobo Co., Ltd.


08/18/16
20160237193 

Method for preparation of polycarboxylate superplasticizer by graft copolymerization of fatty acid vinyl ester onto acrylate polymer


This invention relates to a method for preparing a polycarboxylate superplasticizer by graft copolymerization of fatty acid vinyl ester onto acrylate polymer. In this invention, a type of polycarboxylate superplasticizer by graft copolymerization of fatty acid vinyl ester onto acrylate polymer was synthesized by the processes of polymerization-grafting-alcoholysis-hydrolysis with acrylate and fatty acid vinyl ester as main reactants.
Beijing University Of Technology


08/18/16
20160237178 

Derivatives of n-desulfated glucosaminoglycans and use as drugs


The invention relates to n-desulfated and optionally 2-o-desulfated glucosaminoglycan derivatives, wherein at least part of the adjacent diols and oh/nh2 have been converted into the corresponding aldehyde, which aldehydes have been then reduced to the corresponding alcohol. These products are endowed with heparanase inhibitory activity and anti-tumor activity.
Centro Alta Tecnologia Istituto Di Ricerche Chimiche E Biochimiche "g.ronzoni" S.r.


08/18/16
20160237132 

Fusion polypeptides comprising mucin-domain polypeptide linkers


The invention provides fusion proteins having improved bioactivity comprising a first polypeptide fusion partner and a second polypeptide fusion partner wherein the first fusion partner is linked to the second fusion partner by a mucin-domain polypeptide linker and wherein the bioactivity of the fusion protein of the invention is improved as compared to fusion of the first polypeptide fusion partner and the second polypeptide fusion partner in the absence of the mucin-domain polypeptide linker. Mucin-domain polypeptide linkers comprise a mucin domain that is rich in potential glycosylation sites, and has a high content of serine and/or threonine and proline, which can represent greater than 40% of the amino acids within the mucin domain and further comprise at least about 60% of its mass due to the glycans..
Alkermes, Inc.


08/18/16
20160237050 

Synthesis process for diacetyl epoxy glyceryl oleate


The present invention relates to a process for the synthesis of diacetyl epoxy glyceryl oleate, comprising the steps of: a). Esterification of glycerol and oleic acid at 115-190° c.
Guangzhou Hairma Chemical (gz) Ltd.


08/18/16
20160237049 

Crystal modifications of elobixibat


The present invention relates to crystal modifications of n-{(2r)-2-[({[3,3-dibutyl-7-(methyl-thio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-8-yl]oxy}acetyl)amino]-2-phenylethanolyl}glycine (elobixibat), more specifically crystal modifications i, iv, meoh-1, etoh-1, 1-proh-1 and 2-proh-1. The invention also relates to a process for the preparation of these crystal modifications and to a pharmaceutical composition comprising crystal modification iv..
Elobix Ab


08/18/16
20160236982 

Additive for suspensions


The present invention proposes a polyczuboxylate ether-based additive having the general formula (i) for use as flow modifier in suspensions. The present invention further proposes a method for obtainment of such additive, wherein the method comprises the sequential steps of esterification of polyethylene glycol (peg) with maleic anhydride (ma) and thus obtainment of a chemical product (pegma) and free radical polymerization in a mixture comprising acrylic acid (aa), 2-acrylamido-2 methylpropanesulfonic acid (amps) and pegma as reactants, further comprising water and an initiator, initial ph value of said mixture is within the range between 7.5 and 8.5, and any free oxygen is removed from the mixture throughout the free radical polymerization..
Sabanci Üniversitesi


08/18/16
20160236461 

Coating for aqueous inkjet transfer


An image transfer member (itm) is provided with a skin over its surface in which the skin incorporates a hygroscopic agent. The hygroscopic agent is operable to make the itm skin very hydrophilic or to provide a high surface energy.
Xerox Corporation


08/18/16
20160235852 

Surfactant composition


The present invention relates to a surfactant composition comprising at least one alkylglycoside having the formula cngm wherein c is an alkyl group; n is the number of carbon atoms in the alkyl group and is 14 to 24; said alkyl group being unbranched or branched, saturated or unsaturated, derivatised or non-derivatised; g is a saccharide residue containing 5 to 6 carbon atoms; and m is a number from 4 to 20. It further also relates to its use and application in detergents, emulsifying agents, wetting agents, anti-aggregation and stabilising composition and dispersants comprising the same..
Enza Biotech Ab


08/18/16
20160235834 

Live attenuated vaccines


The present invention refers to a method for the production of live attenuated bacterial strains, suitable as vaccine candidates, comprising the steps of: a. Providing a bacterial strain capable of expressing glutamate racemase and possibly d-amino acid transaminase and comprising a peptidoglycan cell wail, and b.
FundaciÓn Profesor Novoa Santos


08/18/16
20160235786 

Formulation, apparatus, and methods for treatment of brain trauma


A formulation comprising platelet rich plasma (prp) for treatment of patients who have experienced brain injury, consisting of a mixture of human autologous plasma, d5w, glutathione, methylcobalamin, and regular insulin. The formulation is infused directly adjacent to a patient's brain through the nostrils or nares of the nasal cavity.

08/18/16
20160235778 

Compositions containing pufa, uridine and choline and methods of use thereof


The invention is directed to a method for increasing phosphatidylcholine in the blood of a subject comprising administering to the subject a composition having uridine or a metabolic precursor of uridine; choline or a metabolic precursor of choline; and at least one omega-3 fatty acid and/or omega-6 fatty acid, the phosphatidylcholine has a glycerol portion and the glycerol portion is bonded to two fatty acids and the total amount of carbons in the fatty acids is about 16 to 40 carbon atoms.. .
Massachusetts Institute Of Technology


08/18/16
20160235701 

Composition and methods for treating intestinal hyperpermeability


The present invention provides methods, compositions, and kits for treating intestinal hyperpermeability in a subject in need thereof, including conditions such as hyperglycemia and underlying diseases such as diabetes, autism, fibromyalgia, inflammatory bowel disease (ibd), graft versus host disease (gvhd), hiv/aids, multiple organ dysfunction syndrome, irritable bowel syndrome (ibs), celiac disease, eczema, psoriasis, acute pancreatitis, parkinson's disease, depression, chronic fatigue syndrome, asthma, multiple sclerosis, arthritis, ankylosing spondylitis, nonalcoholic fatty liver disease, alcoholic cirrhosis, environmental enteropathy, or kwashiorkor.. .

08/18/16
20160235699 

Compositions comprising citrulline and leucine and their use in the treatment of diabetes and metabolic syndrome


The present disclosure relates generally to compositions that comprise citrulline and leucine or a metabolite thereof including, for example, a synergistic amount of citrulline and leucine. Such compositions may be used in methods for the treatment of metabolic syndrome, hyperglycemia, and/or hyperinsulinemia..
Nestec S.a.


08/18/16
20160235669 

Process for preparing water dispersions containing high concentration of nano/submicron, hydrophobic, functional compounds and water dispersions obtainable therefrom


The present invention provides a process for preparing a water dispersion containing a high concentration of nano/submicron, hydrophobic, functional compounds. The process is carried out by using a complex stabilizer having an hlb value of about 10 to about 17, comprising lecithin and at least one non-phospholipid selected from polysorbate, sucrose ester, and polyglycerol fatty acid ester; selecting a specific weight ratio of the hydrophobic functional compounds and the stabilizer; and using homogenization technique, media milling technique, and/or centrifugal technique.
Food Industry Research And Development Institute


08/18/16
20160235643 

Cosmetic composition comprising a combination of surfactants of carboxylate, acylisethionate and alkyl(poly)glycoside type


Cosmetic composition comprising a combination of surfactants of carboxylate, acylisethionate and alkyl(poly)glycoside type the invention relates to a cosmetic composition comprising: one or more anionic surfactants of carboxylate type, chosen from the compounds of formule (i), r—(och2ch2)nw—(chy1)p-coox (i), in a content of greater than or equal to 3% by weight relative to the total weight of the composition, one or more anionic surfactants of (c8-c22) acylisethionate type, and -one or more nonionic surfactants of alkyl(poly)glycoside type. This composition is intended for the cosmetic treatment of keratin materials, and in particular for washing the hair.
L'oreal


08/18/16
20160235102 

Sweetener composition, sweetener products, and methods of sweetening


A method of reducing oral cavity and tongue coating adherence and tongue numbing effects of a sweetener composition and imparting a more sugar-like temporal and flavor profile to a high potency sweetener, that includes providing to a person a sweetener composition that includes an encapsulated high potency sweetener or a high potency sweetener included in an emulsified mixture. The high potency sweetener is selected from the group consisting of: mogroside iv, mogroside v, luo han guo sweetener, siamenoside, monatin and its salts (monatin ss, ra rs, sr).
Almendra Americas, Llc


08/18/16
20160235099 

Method for producing agent for improving untangling of noodles


An object of the present invention is to provide a method for producing an untangling-improving agent for inhibiting quality deterioration such as a difficulty in untangling after storage and efficiently producing tasty noodles, and to provide noodles prepared by using the untangling-improving agent. The untangling properties of noodles can be improved, and at the same time, the elasticity and chewiness of noodles can be maintained by adding, to noodles, an untangling-improving agent for noodles obtained by incorporating monoglycerol fatty acid ester and protein, wherein the monoglycerol fatty acid ester and protein are in the emulsified state..
Fuji Oil Holdings Inc.


08/18/16
20160235085 

Oil and fat composition for non-tempering-type chocolate and oil and fat composition for tempering-type chocolate


A specific amount of malonylisoflavone glycosides that are poorly soluble in oil and fat is contained in an oil and fat for non-tempering-type chocolate or an oil and fat for tempering-type chocolate, and thus an oil and fat composition for chocolate capable of enhancing chocolate flavors (a good milky taste, a sweet taste, a cacao flavor, etc.) without affecting the physical properties of chocolate and chocolate containing the said oil and fat composition are shown.. .
Fuji Oil Holdings Inc.


08/11/16
20160233547 

Electrochemical energy storage device


An exemplary electrochemical energy storage device includes: a positive electrode including a positive electrode active material; a negative electrode including a negative electrode active material; and a non-aqueous electrolytic solution including licl, at least one of li(xso2nso2y) (where x and y are any of f, cnf2n+1 and (cf2)m, and (cf2)m forms a cyclic imide anion) and libf4, and at least one of tetrahydrofuran and a polyethylene glycol of which both terminals are alkyl groups, the non-aqueous electrolytic solution being in contact with the positive electrode and the negative electrode, wherein the positive electrode active material includes a chloride of cu, bi or ag, or the negative electrode active material includes magnesium chloride.. .
Kyoto University


08/11/16
20160231328 

Human fc-bearing igg antibodies to polyethylene glycol


Polyethylene glycol (peg) is often conjugated with therapeutic proteins to enhance their pk properties. Peg may, however, be immunogenic, and the presence of peg in food and cosmetics is believed to result in pre-existing anti-peg antibodies in humans.
Bristol-myers Squibb Company


08/11/16
20160230205 

Activated formylglycine-generating enzymes and methods of producing and using the same


The present disclosure provides activated formylglycine-generating enzymes (fge), methods of producing activated fge, and their use in methods of producing a protein comprising a formylglycine (fgly) residue. The methods of producing activated fge, as well as methods of use of activated fge in producing fgly-containing proteins, include both cell-based and cell-free methods.
R.p. Scherer Technologies, Llc


08/11/16
20160230199 

Method for producing oil containing polyunsaturated fatty acid using lipase


A method for lowering saturated fatty acid content, the method comprising concentrating polyunsaturated fatty acid using a lipase having low reactivity for the polyunsaturated fatty acid to react with a glyceride containing a polyunsaturated fatty acid; wherein the lipase reaction is performed at a temperature of not more than 25° c.. .
Nippon Suisan Kaisha, Ltd.


08/11/16
20160230155 

Modified sulfamidase and production thereof


Disclosed herein are a modified sulfamidase, a composition comprising a modified sulfamidase, as well as methods for preparing a modified sulfamidase and therapeutic use of such a sulfamidase. In particular, the present disclosure relates to a modified sulfamidase comprising substantially no epitopes for glycan recognition receptors, thereby enabling transportation of said sulfamidase across the blood brain barrier of a mammal, wherein said sulfamidase has catalytic activity in the brain of said mammal..
Swedish Orphan Biovitrum Ab (publ)


08/11/16
20160230106 

Production of biodiesel from scum


A method for production of a biodiesel is described herein. The method for production of a biodiesel comprises (a) separating solids from a waste oil composition to provide a clarified oil composition; (b) acidifying the clarified oil composition to produce an acidified oil composition including free fatty acids derived from the waste oil; (c) converting at least a portion of the free fatty acids in the acidified oil composition to glycerides to provide a glyceride composition; and (d) reacting at least a portion of the glycerides in the glyceride composition with methanol to form fatty acid methyl ester to provide a biodiesel composition..

08/11/16
20160230101 

Additives to enhance metal and amine removal in refinery desalting processes


It has been discovered that metals and/or amines can be removed or transferred from a hydrocarbon phase to a water phase in an emulsion breaking process by using a composition that contains water-soluble hydroxyacids. Suitable water-soluble hydroxyacids include, but are not necessarily limited to glycolic acid, gluconic acid, c2-c4 alpha-hydroxy acids, poly-hydroxy carboxylic acids, thioglycolic acid, chloroacetic acid, polymeric forms of the above hydroxyacids, poly-glycolic esters, glycolate ethers, and ammonium salt and alkali metal salts of these hydroxyacids, and mixtures thereof.
Baker Petrolite Llc


08/11/16
20160229982 

Integrated process for treating recycled pet and ptt materials


A process for producing a polyester polyol comprising reacting a recycle stream selected from recycled pet carpet, carpet fiber, containers, textiles, articles or mixtures thereof, with a glycol in a reactor, thereby forming a digested product stream comprising polyols, and an undigested stream; and then reacting the digested product stream with a hydrophobe selected from dimer fatty acids, trimer fatty acids, oleic acid, ricinoleic acid, tung oil, corn oil, canola oil, soybean oil, sunflower oil, bacterial oil, yeast oil, algae oil, castor oil, triglycerides or alkyl carboxylate esters having saturated or unsaturated c6-c36 fatty acid units, saturated or unsaturated c6-c36 fatty acids, alkoxylated castor oil, saturated or unsaturated c9-c18 dicarboxylic acids or diols, cardanol-based products, recycled cooking oil, branched or linear c6-c36 fatty alcohols, hydroxy-functional materials derived from epoxidized, ozonized, or hydroformylated fatty esters or acids, or mixtures thereof.. .
Resinate Materials Group, Inc.


08/11/16
20160229981 

Integrated process for treating recycled streams of pet and ptt


A process for producing a polyester polyol comprising reacting a recycle stream selected from recycled pet carpet, carpet fiber, containers, textiles, articles or mixtures thereof, with a glycol in a reactor, thereby forming a digested product stream comprising polyols, and an undigested stream; and then reacting the digested product stream with a hydrophobe selected from dimer fatty acids, trimer fatty acids, oleic acid, ricinoleic acid, tung oil, corn oil, canola oil, soybean oil, sunflower oil, bacterial oil, yeast oil, algae oil, castor oil, triglycerides or alkyl carboxylate esters having saturated or unsaturated c6-c36 fatty acid units, saturated or unsaturated c6-c36 fatty acids, alkoxylated castor oil, saturated or unsaturated c9-c18 dicarboxylic acids or diols, cardanol-based products, recycled cooking oil, branched or linear c6-c36 fatty alcohols, hydroxy-functional materials derived from epoxidized, ozonized, or hydroformylated fatty esters or acids, or mixtures thereof.. .
Resinate Materials Group, Inc.


08/11/16
20160229980 

Integrated process for treating recycled streams of pet and ptt


A process for producing a polyester polyol comprising reacting a recycle stream selected from recycled pet carpet, carpet fiber, containers, textiles, articles or mixtures thereof, with a glycol in a reactor, thereby forming a digested product stream comprising polyols, and an undigested stream; and then reacting the digested product stream with a hydrophobe selected from dimer fatty acids, trimer fatty acids, oleic acid, ricinoleic acid, tung oil, corn oil, canola oil, soybean oil, sunflower oil, bacterial oil, yeast oil, algae oil, castor oil, triglycerides or alkyl carboxylate esters having saturated or unsaturated c6-c36 fatty acid units, saturated or unsaturated c6-c36 fatty acids, alkoxylated castor oil, saturated or unsaturated c9-c18 dicarboxylic acids or diols, cardanol-based products, recycled cooking oil, branched or linear c6-c36 fatty alcohols, hydroxy-functional materials derived from epoxidized, ozonized, or hydroformylated fatty esters or acids, or mixtures thereof.. .
Resinate Materials Group, Inc.


08/11/16
20160229952 

Functional biodegradable polymers


Biodegradable polyesters are made by synthesizing copolymers derived from biodegradable hydroxyacid monomers as well as from hydroxyacid monomers containing a functional group such as an azide group, a halogen group, a thioacetate group, and the like. Preferably, the functionalized biodegradable polyester copolymers are derived from a functionalized hydroxyacid such as a homolog of lactic acid and/or glycolic acid with the copolyester thus containing functional groups on the backbone thereof.

08/11/16
20160229895 

Collagen-binding synthetic peptidoglycans for use in vascular intervention


This invention relates to collagen-binding synthetic peptidoglycans. More particularly, this invention relates to collagen-binding synthetic peptidoglycans for use in vascular intervention procedures.
Symic Ip, Llc.


08/11/16
20160229869 

Compounds and methods for preventing or treating sensory hair cell death


Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing or treating hearing loss. The compounds and pharmaceutical compositions described herein prevent or treat hair cell death.
Oricula Therapeutics Llc


08/11/16
20160229848 

Benzazepine ketone compounds as glycogen phosphorylase inhibitor, preparation method therefor, and medical uses


The present invention relates to the field of pharmaceutical chemistry, and particularly to a novel class of benzazepine ketone derivatives (i), their preparation method and their pharmaceutical uses. The compounds have glycogen phosphorylase inhibiting effect and can be used in the preparation of anti-diabetes and its complications medicaments, anti-cerebral ischemia medicaments, anti-cardiovascular diseases medicaments, blood lipid-lowering medicaments, weight-reducing medicaments, anti-atherosclerosis medicaments, medicaments for treating metabolic syndrome or anti-tumor medicaments.
Chengde Medical University


08/11/16
20160229822 

Crystal modifications of elobixibat


The present invention relates to crystal modifications of n-{(2r)-2-[({[3,3-dibutyl-7-(methyl-thio)-1,1-dioxido-5-phenyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-8-yl]oxy}acetyl)amino]-2-phenylethanolyl}glycine (elobixibat), more specifically crystal modifications i, iv, meoh-1, etoh-1, 1-proh-1 and 2-proh-1. The invention also relates to a process for the preparation of these crystal modifications and to a pharmaceutical composition comprising crystal modification iv..
Elobix Ab


08/11/16
20160229816 

Cyanotriazole compounds


Wherein each symbols are defined in the specification, or a salt thereof. The compound or a salt thereof stimulates the citric acid cycle activity and/or improves hyperglycemia with less side effects, and excellent safety, and therefore, it is useful for treating and/or preventing diseases or disorders on which citric acid cycle activation and/or improvement of hyperglycemia has a prophylactic and/or therapeutic effect, for example, diabetes, impaired glucose tolerance, insulin resistance, diabetic complications, obesity, dyslipidemia, hepatic steatosis, atherosclerosis and/or cardiovascular disease, as well as diseases or disorders that would benefit from stimulating energy expenditure..

08/11/16
20160229785 

Continuous process for extraction of unsaturated triglycerides from fish oil


Wherein tc is a total number of carbon atoms in the fatty acid strand, and db is the number of double bonds in the fatty acid strand. Crude fish oil diluted in non-polar solvent directly passed to an smb zone, comprising a normal phase separation with a hydrophilic stationary phase agent and a non-polar/organic polar mobile phase desorbent to provide an omega-3 fatty acid enriched triglyceride product..

08/11/16
20160229722 

Synthetic acid and associated methods


Glycine is an organic compound that can be used in the making of a synthetic acid that obviates all the drawbacks of strong acids such as hydrochloric acid. The new compound is made by dissolving glycine in water, in a weight ratio of approximately 1:1 to 1:1.5.
Green Products & Technologies, L.l.c.


08/11/16
20160228999 

Flux and manufacturing electronic device


A flux used for bonding a solder includes: 75 wt % or more of ethylene glycol polymer represented by the following formula: ho(ch2ch2o)nh [n is an integer of 4 or more], wherein an evaporation of the ethylene glycol polymer while being heated is terminated at a temperature equal to or greater than a bonding temperature of the solder.. .
Fujitsu Limited


08/11/16
20160228612 

Artificial bone nanocomposite and manufacture


A composition suitable for bone replacement is provided. The composition is a nanocomposite matrix, resembling both the structure and the properties of natural bone, including morphology, composition and mechanical characteristics.

08/11/16
20160228610 

Tissue engineering using progenitor cells to catalyze tissue formation by primary cells


Methods of regenerating tissue using progenitor cells in combination with primary cells from a target tissue are disclosed. The progenitor cells catalyze proliferation and tissue production by primary cells allowing the use of fewer primary cells from a target tissue for effective tissue regeneration.
The Board Of Trustees Of The Leland Stanford Junior University


08/11/16
20160228601 

Biocompatible crosslinked hydrogels, drug-loaded hydrogels and methods of using the same


Disclosed are hydrogel compositions formed by the mixture of a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more electrophilic groups, and a tetramethylmethane substituted with one or more polyethylene glycols, and wherein each polyethylene glycol substituent is independently further substituted with one or more nucleophilic groups. Disclosed are also methods of preparing the above hydrogels.

08/11/16
20160228565 

Polyamide based peptidodendrimer conjugates


The present invention relates to monofunctional and bifunctional peptidodendrimer conjugates that contain a polyamide dendrimer conjugated to herpes simplex virus-1 glycoprotein-derived peptides. Also disclosed are pharmaceutical compositions containing these peptidodendrimer conjugates and methods of using these peptidodendrimer conjugates (e.g., to inhibit hsv-1 viral entry and to treat or prevent hsv-1 infection)..
New York University


08/11/16
20160228508 

Cartilage product


The present invention relates to a method for preparing a cartilage product comprising a protein hydrolysate with a degree of hydrolysis comprised between 0.5% and 3.0%, at least one glycosaminoglycan and at least one growth factor. The present invention also relates to the cartilage product obtainable through said method.
Bioiberica, S.a.


08/11/16
20160228467 

Peg or peg block copolymer for treating colorectal cancer


The present invention relates to methods for and of treating, ameliorating or preventing colorectal cancer (crc) in humans using polyethylene glycol (peg) or a peg block-copolymer such as pluronic® f68. Compositions for use in treating, ameliorating and/or preventing crc comprising peg are also disclosed.
Norgine Bv


08/11/16
20160228420 

Polyethylene glycol-containing composition


The present invention relates to a pharmaceutical composition comprising a compound represented by the formula (1) or a salt thereof and polyethylene glycol.. .
Santen Pharmaceutical Co., Ltd.


08/11/16
20160228400 

Compositions capable of enhancing thermogenesis and uses thereof


The present invention refers to novel compositions and to methods of using the compositions to treat and/or prevent obesity, obesity-related diseases or disorders (e.g., hyperglycemia, hyperinsulinemia, elevated hemoglobin a1c (hba1c), diabetes, or cardiovascular disease), and overweight. This invention also generally relates to compositions and to methods of using the compositions to increase basal metabolic rate..
Specialty Nutrition Group, Inc.


08/11/16
20160228384 

Emulsion containing two oils and stabilizers


The present invention relates to improved formulations for administration lipophilic drugs, and in particular to improved propofol formulations. Emulsion of the present invention preferably comprise oil droplets of a mean oil particle diameter of 80-300 nanometers; and a continuous aqueous phase comprising a lipophilic drug in an amount 0.5-5.0% by weight relative to the weight of the total emulsion, wherein said lipophilic drug has a solubility in water of less than 1 mg/ml; a primary oil physiologically suitable for parenteral administration to a mammal comprising plant-derived biocompatible long chain triglycerides; and a secondary oil comprising an ethyl ester of a saturated, unbranched carboxylic acid of 4-8 carbon atoms or an unbranched alkyl esters of acetic acid, said alkyl residue having 4-8 carbon atoms, or combination thereof, the combined percentage by weight of the oil components not exceeding about 10 percent..
Nanomedex, Llc


08/11/16
20160228344 

Anhydrous base for cosmetic or drug formulations


Embodiments disclosed herein include a deodorant or antiperspirant base that includes cyclomethicone and propylene glycol dispersed in the cyclomethicone.. .

08/11/16
20160227832 

Formulations of water-soluble derivatives of vitamin e and compositions containing same


Provided are compositions that contain water-soluble vitamin e derivative mixtures (compositions), such as tocopheryl polyethylene glycol succinate (tpgs), tpgs analogs, tpgs homologs and tpgs derivatives. The water-soluble vitamin e mixtures contain mixtures that include dimers and monomers of the vitamin e derivative, where the amount of dimer is greater than 12%, such as 29%, 35%, 50%, 60%, and the amount of monomer is less than 87%, by weight, of the water-soluble vitamin e derivative mixture.
Virun, Inc.


08/11/16
20160227818 

Preservation of animal feed and hydrolysis of polysaccharides using amino acids as salts or with acids


In some aspects, the present disclosure relates to a method of hydrolyzing a polysaccharide to obtain the corresponding saccharides using an amino acid solution. In some embodiments, the present disclosure provides a method of using an amino acid salt such as hydrogen glycine in a solution to obtain a monosaccharide such as glucose, xylose, or fructose..
The Board Of Regents Of The University Of Texas System


08/11/16
20160227810 

Structured triacylglycerols and methods for making the same


The present disclosure provides structured lipids (sls) and mixtures of sls including structured triacylglycerols (tags), methods of producing the sls, products including the sls and methods of making the products.. .
King Abdulaziz University


08/11/16
20160227764 

Method for preserving natural grass which has been extracted


The present invention discloses a method for preserving natural turf that has been pulled up, characterised in that said method comprises the steps of: a) pulling up the sods of natural turf; b) laying out the sods on a planar surface; c) applying a preservation composition comprising from 1 wt. % to 99 wt.
Verdissimo Forever Young, S.a.


08/04/16
20160225480 

Conductive polymer film


The present application relates to a conductive polymer film having excellent coating properties with respect to a hydrophobic organic material and electrical conductivity, and more specifically, to a conductive polymer film including a conductive polymer layer; and a coating layer formed on the conductive polymer layer and including a surfactant having a hydrophile-lipophile balance (hlb) of 10 or more, polyethylene glycol, or a combination thereof.. .
Lg Chem, Ltd.


08/04/16
20160222430 

D-ala-d-ala-based dipeptides as tools for imaging peptidoglycan biosynthesis


Disclosed herein are compositions for assessing peptidoglycan biosynthesis in bacteria using modified dipeptides containing a bioorthogonal tag and applying novel post-labeling methods to label the bioorthogonal tag. The resultant, labeled peptidoglycan structures are amenable for identifying bacteria by microscopic visualization..
Indiana University Research And Technology Corporation


08/04/16
20160222398 

Engineering cyclopropane fatty acid accumulation in plants


Heterologous expression of e. Coli cyclopropane synthase in genotypic and phenotypic fad2fae1 plants facilitates accumulation of cyclopropane fatty acids.
Brookhaven Science Associates, Llc


08/04/16
20160222361 

Myrmecia incisa reisigl diacylglycerol acyltransferase gene sequence and use thereof


Disclosed are an amino acid sequence of myrmecia incise reisigl diacylgycerol acyltransferase, an encoding gene sequence and application thereof. Specifically, based on myrmecia incise reisigl transcriptome sequencing data, cloning to obtain full-length cdna and full-length dna sequences of a myrmecia incise reisigl diacylgycerol acyltransferase gene, and expressing the gene in yeast tag synthesis defect strain h1246, finding that an encoded protein thereof has a capability for synthesizing a tag, and using a substrate preference experiment to prove that the encoded protein of the gene tends to c18:1 fatty acid..
Shanghai Ocean University


08/04/16
20160222358 

Plants with increased growth over expressing a mitochondrial glycine decarboxylase complex subunit


The present invention relates to the field of plant molecular biology and concerns methods for enhancing photorespiration, photosynthesis, growth or yield in plants by modulating the expression of the glycine decarboxylase, also known as the glycine cleavage system. The present invention also provides recombinant constructs useful in the methods in the invention.
Bayer Cropscience Nv


08/04/16
20160222320 

Synergistic stain removal through novel chelator combination


The invention relates to a concentrated detergent composition comprising an alkali metal hydroxide, methylglycinediacetic acid, glutamic acid n,n-diacetic acid, and alkali metal tripolyphosphate. The composition is particularly suited to remove tea and coffee soil in warewashing applications..
Ecolab Usa Inc.


08/04/16
20160222319 

A stain treatment additive


The present invention provides a stain treatment additive which comprises an ester of glycerol and/or polyglycerol and a c12 to c30 fatty acid, wherein the glycerol and/or polyglycerol has been alkoxylated with up to 30 mols of an alkylene oxide and its use in a textile cleaning composition, a laundry detergent composition, a stain remover composition and a method of cleaning a textile.. .
Croda International Plc


08/04/16
20160222318 

Synergistic stain removal through novel chelator combination


The invention relates to a concentrated detergent composition comprising an alkali metal carbonate, methylglycinediacetic acid, glutamic acid n,n-diacetic acid, and alkali metal tripolyphosphate. The composition is particularly suited to remove tea and coffee soil in warewashing applications..
Ecolab Usa, Inc.


08/04/16
20160222237 

Ink compositions comprising surfactants having limited solubility


Disclosed herein are ink compositions comprising a self-dispersed pigment in a liquid vehicle. The liquid vehicle can comprise a solvent/water mixture in which the composition further comprises a surfactant system having limited solubility/compatibility with the liquid vehicle.
Cabot Corporation


08/04/16
20160222218 

Tunable nonfouling surface of oligoethylene glycol


An article having a nonfouling surface thereon is comprises: (a) a substrate having a surface portion; (b) a linking layer on the surface portion; and (c) a polymer layer formed on the linking layer, preferably by the process of surface-initiated polymerization of monomeric units thereon, with each of the monomeric units comprising a monomer core group having at least one protein-resistant head group coupled thereto, to thereby form a brush molecule on the surface portion. The brush molecule comprising a stem formed from the polymerization of the monomer core groups, and a plurality of branches formed from the hydrophilic head group projecting from the stem.
Duke University


08/04/16
20160222212 

Asulfonate discrete peg based dyes


Disclosed are discrete pegylated dyes, that is, dyes, generally ones that are fluorescent, but could also include chemiluminescent or electrochemiluminescent and related dye or dye precursors, that have discrete peg constructs chemically attached in various configurations on the dye, and in the entire range of constructs, discrete peg compounds (polyethylene glycol oligomers that are made synthetically according to methods disclosed in u.s. Pat.
Equip, Llc


08/04/16
20160222203 

Synthetic polymeric materials and devices thereof


Provided herein is a polymeric material comprising a polymer host; and a guest molecule comprising a glycosaminoglycan; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. In some embodiments, the polymer host comprises a silicone-based polymer.
Colorado State University Research Foundation


08/04/16
20160222137 

Compositions and anti-sickling of red blood cells in sickle cell disease


A nano-composition that includes nanoparticles, a method of forming the nano-composition, and a method of using the composition. The nanoparticles include a polycationic polymer ionically bonded to one or more polyanionic glycosaminoglycans (gags), wherein the polycationic polymer is chitosan, methylated chitosan, poly l-lysine, or poly l-arginine..

08/04/16
20160222136 

A fractionating dextrin


A method for fractionating dextrin, belonging to the technical field of food processing. In principle, the method for fractionating dextrin of the present invention is based on the fact that the dextrin is incompatible with polyethylene glycol in aqueous solution and a larger molecular weight of the dextrin results in more significant incompatibility with polyethylene glycol.
Jiangnan University


08/04/16
20160222075 

Production of glycoproteins using manganese


Culture media comprising manganese and methods of culturing cells to improve sialylation and glycosylation of glycoproteins are provided.. .
Amgen Inc.


08/04/16
20160222064 

Hyaluronic acid-binding synthetic peptidoglycans, preparation, and methods of use


This invention pertains to the field of hyaluronic acid-binding synthetic peptidoglycans and methods of forming and using the same.. .
Symic Biomedical, Inc.


08/04/16
20160222049 

Aminoglycoside antibiotics with reduced ototoxicity


This disclosure relates generally to aminoglycoside derivatives of formula (i) as described herein. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating bacterial infections by administering these compounds and pharmaceutical compositions to subjects in need thereof..
The Board Of Trustees Of The Leland Stanford Junior University




Gly topics: Door Assembly, Swimming Goggles, Transverse, Alkoxylate, Fluoropolymer, Air Cleaning, Rotor Shaft, Aspect Ratio, Disconnect, Synchronization, Remote Control, Ethylene Glycol, Surfactant, Combustion, Steviol Glycosides

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