Follow us on Twitter
twitter icon@FreshPatents


Gene patents

      

This page is updated frequently with new Gene-related patent applications.

SALE: 530+ Gene-related patent PDFs



 Digital broadcasting system and  processing data in digital broadcasting system patent thumbnailDigital broadcasting system and processing data in digital broadcasting system
A digital broadcasting system and a data processing method are disclosed. A receiver receives a broadcast signal including mobile service data and main service data.
Lg Electronics Inc.


 Base station control device and  operating same patent thumbnailBase station control device and operating same
The present invention discloses a base station control device which controls the base station management and the carrier aggregation (ca) function according to a heterogeneous network environment, such that an optimum system throughput can be obtained in the heterogeneous network environment through the ca function, and an operating method of the base station control device.. .
Industry-academic Cooperation Foundation, Yonsei University


 Systems and methods for ranking and providing related media content based on signals patent thumbnailSystems and methods for ranking and providing related media content based on signals
Systems, methods, and non-transitory computer-readable media can detect a trigger to generate a set of media content items associated with at least one of a particular media content item or a user viewing the particular media content item. A plurality of content generators can be utilized to generate a plurality of subsets of media content items.
Facebook, Inc.


 Techniques for routing from an endpoint with simultaneous associations to multiple networks patent thumbnailTechniques for routing from an endpoint with simultaneous associations to multiple networks
A node within a wireless endpoint device may be coupled to multiple heterogeneous networks simultaneously. The node is configured to select between the different networks based on various constraints associated with the endpoint device, applications executing on the endpoint device, traffic routed by the endpoint device, and constraints associated with the multiple networks.
Silver Spring Networks, Inc.


 Unified encryption configuration management and setup system patent thumbnailUnified encryption configuration management and setup system
The present technology relates to the field of configuration and setup of encrypted computer network transmission systems. In particular, the present technology relates to setting up and configuring network encryption systems, including macsec, internet protocol security (ipsec), and tls protocols, in heterogeneous networks over wireless area networks (wan), wireless local area network (wlan) or cellular links.
Pacific Star Communications, Inc.


 Information processing  authenticating message patent thumbnailInformation processing authenticating message
An information processing apparatus includes a shared information generation unit for generating shared information via a network, a communication unit configured to receive a message, a shared information verification unit configured to compare shared information in the message with the information generated by the shared information generation unit, and verify validity of the shared information in the message based on the comparison, a security code generation unit for generating a security code based on the shared information, a security code verification unit configured to compare a security code in the message with the security code generated by the security code generation unit, and verify correctness of the shared information in the message based on the comparison, and a processing determination control unit configured to determine normality of the message on the based on the verification by the shared information verification unit and the verification by the security code verification unit.. .
Hitachi Automotive Systems, Ltd.


 Polar code generation patent thumbnailPolar code generation
A polar code generation method and device are disclosed. The method includes: determining an index set of information bits of a polar code according to a first modulation scheme; and encoding the polar code according to the index set of the information bits of the polar code..
Huawei Technologies Co., Ltd.


 Multi-stage frequency dividers and poly-phase signal generators patent thumbnailMulti-stage frequency dividers and poly-phase signal generators
An electronic latch circuit, a 4-phase signal generator, a multi-stage frequency divider and a poly-phase signal generator are disclosed. The electronic latch circuit comprises an output circuit comprising a first output and a second output.
Telefonaktiebolaget Lm Ericsson (publ)


 Power conversion device patent thumbnailPower conversion device
Provided is a power conversion device capable of suppressing common-mode voltage fluctuation resulting from output voltage transitioning. A power conversion device 1 is provided with n voltage control units 21 to 2n, a full-bridge conversion unit having four switches qb1 to qb4, a clamp unit having holding switches qc1 and qc2, and a control unit 5.
Panasonic Intellectual Property Management Co., Ltd.


 Method and  radial electromagnetic power arrays patent thumbnailMethod and radial electromagnetic power arrays
Multiple arrays of linear motors and generators are combined in a radial configuration to provide high mechanical efficiency to deliver power in a single plane of motion to a common crankshaft. Magnet core assemblies for the motors and generators use powerful rare earth magnets positioned within an outer flux containment shell comprising a highly-magnetically-permeable ferrous-alloy to provide high power density.
Juiced Planet, Llc


Charge/discharge management device

A charge/discharge management device is provided in power generation equipment including a power generation system in which generated power fluctuates and a storage battery system and connected to a power system. The power generation system includes a power meter that detects the generated power.
Toshiba Mitsubishi-electric Industrial Systems Corporation

Battery control circuit for power generation system using renewable energy

The battery control circuit includes: a battery; a dc power supply unit; a first dc-dc converter providing a current path in a first direction of supplying the dc energy from the dc power supply unit to the battery, and a current path in a second direction of discharging the dc energy in the battery to a ground; a first capacitor fully discharging the battery in a manner that the sum of a voltage across the first capacitor and a voltage across the flow battery to be higher than an output voltage of the first dc-dc converter; a second dc-dc converter supplying the dc energy from the dc power supply unit to the first capacitor; and a controller controlling the first dc-dc converter to form the current flow path in the second direction when a number of times of charging and discharging the flow battery reaches a preset number.. .
Lsis Co., Ltd.

Regeneration of cathode material of lithium-ion batteries

Lithium metal oxides may be regenerated under ambient conditions from materials recovered from partially or fully depleted lithium-ion batteries. Recovered lithium and metal materials may be reduced to nanoparticles and recombined to produce regenerated lithium metal oxides.
University Of Calcutta

Heterogeneous integration using wafer-to-wafer stacking with die size adjustment

A method is provided for three-dimensional wafer scale integration of heterogeneous wafers with unequal die sizes that include a first wafer and a second wafer. The method includes selecting a periodicity for the second wafer to be manufactured that matches the periodicity of the first wafer.
International Business Machines Corporation

Heterogeneous integration using wafer-to-wafer stacking with die size adjustment

A method is provided for three-dimensional wafer scale integration of heterogeneous wafers with unequal die sizes that include a first wafer and a second wafer. The method includes selecting a periodicity for the second wafer to be manufactured that matches the periodicity of the first wafer.
International Business Machines Corporation

Monolithically integrated semiconductor switch, particularly circuit breaker

A monolithically integrated semiconductor switch, particularly a circuit breaker, has regenerative turn-off behaviour. The semiconductor switch has two monolithically integrated field effect transistors, for example a p-jfet and a n-jfet.
Fraunhofer-gesellschaft Zur Foerderung Der Angewandten Forschung E.v.

Selectively lateral growth of silicon oxide thin film

Implementations disclosed herein generally relate to methods of forming silicon oxide films. The methods can include performing silylation on the surface of the substrate having terminal hydroxyl groups.
Applied Materials, Inc.

Method for reading an eeprom and corresponding device

A read amplifier of a memory device has two current generators, an inverter, and five transistors. The inverter is connected to the second current generator.
Stmicroelectronics (rousset) Sas

System, method, and computer program product for rendering at variable sampling rates using projective geometric distortion

A system, method, and computer program product are provided for rendering at variable sampling rates. Vertex coordinates for 3d primitive are received from a shader execution unit, and an arithmetic operation is performed on the vertex coordinates by fixed operation circuitry to produce modified vertex coordinates in homogeneous coordinate space.
Nvidia Corporation

Estimating document reading and comprehension time for use in time management systems

A method and device. The device determines an initial estimate of an amount of time for a generic user to read a document, wherein the initial estimate is determined based on a value of one or more parameters associated with the document.
International Business Machines Corporation

Systems and methods for regulating a microgrid

A microgrid system includes one or more power generators configured to provide electrical energy. The microgrid system also includes a localized distribution network coupled to the one or more power generators, coupled to the one or more loads, and coupled to an external grid.
General Electric Company

Generator management system and method that selectively activate at least one of a plurality of generators in a power generation system

A method of determining an operation of at least one of a plurality of generators in a power generation system. The method includes identifying a system parameter that is related to operation of the power generation system; and determining which of the plurality of generators to operate to minimize fuel consumption of the power generation system based on the system parameter.
Kohler Co.

Flight simulation and control a unmanned aerial vehicle with regenerative fuel cells and solar cells for high altitude long endurance, and a control apparatus thereof

Provided are a flight simulation and control method of a unmanned aerial vehicle with regenerative fuel cells and solar cells for high altitude long endurance, and a control apparatus thereof. The high altitude long endurance simulation method for an unmanned aerial vehicle based on regenerative fuel cells and solar cells includes: a variable inputting step of inputting design variables of the unmanned aerial vehicle based on regenerative fuel cells and solar cells; a modeling step of performing modeling of the unmanned aerial vehicle based on regenerative fuel cells and solar cells using the design variables input in the variable inputting step; and an analyzing step of analyzing a modeling result in the modeling step to perform a high altitude long endurance simulation while controlling any one of the design variables input in the variable inputting step..
Korea Institute Of Energy Research

Circuit interrupter and system for testing the same

A circuit interrupter includes a sensor structured to output a sensor signal, a control unit structured to receive an external control signal, the control unit including: a communication interface structured to receive the external control signal, and a waveform generator structured to generate a waveform equivalent to the sensor signal in response to the external control, and a signal processing circuit structured to receive and process the sensor signal or the generated waveform and to output the processed sensor signal or generated waveform to the control unit.. .
Eaton Corporation

A prognosis of ovarian cancer, patient's stratification

There are no reliable clinical bio-markers of survival prognosis, patient's risk stratification and treatment prediction for epithelial ovarian cancers(eoc). The most common type of the human eoc is a high grade serous eoc.
Agency For Science, Technology And Research

Method of identifying cosmetic agents for moisturizing skin

Methods of identifying potential skin moisturizing actives for the treatment of dry skin and method of formulating a moisturizing skin care composition using actives identified by the method. Moisturizing agents can be identified by comparing the transcriptional profile of a skin tissue sample contacted by a test agent to a negative or positive control to determine if the regulation of certain genes corresponds to the appropriate direction of regulation indicated by the control.
The Procter & Gamble Company

Diffusion chromatography fluid analysis

Methods, systems, devices, and products for evaluating a fluid. Methods include introducing a sample comprising the fluid to a solvating fluid at a point in a chamber associated with the instrument at a first time to create a heterogeneous admixture; measuring concentrations of each of a plurality of components in the admixture at a plurality of distances from the point in the chamber at, at least one additional time later than the first time, each of the plurality of distances being non-zero; and estimating a relative concentration for each of the plurality of components in the fluid by extrapolating the relative concentration of each of the plurality of components in the sample at the point at the first time using the measured concentrations in the admixture at the plurality of distances..
Baker Hughes Incorporated

Gas-measuring chip, portable chip measurement operating a portable chip measurement system

A gas-measuring chip (10), used with a gas-measuring device (100) of a portable chip measurement system, has a carrier (11) and measuring channels (20, 20′, 20″). A regenerable, nonconsumable sensor (30, 30′, 30″) is arranged in each measuring channel.
Dräger Safety Ag & Co. Kgaa

Generic user interface system

A generic user interface for rapid application development on a stand-alone control platform. A user interface may be designed using generic menu methodology consisting of predefined tables, fonts, and templates, such that table entries and menu selections are made based on the platform.
Honeywell International Inc.

Systems and methods for generating superheated steam with variable flue gas for enhanced oil recovery

Systems and methods are disclosed for producing a superheated steam having a specified ratio of water vapor to combustion gases for injection into a well to enhance heavy oil production. Embodiments comprise indirect-contact steam generators and direct-contact steam generators..
Energy Analyst Llc.

Steam generator with a horizontal heat-exchange tube bundle and its assembly method

The invention relates to steam generators for vver nuclear power plants. We claim a steam generator with a horizontal heat-exchange tube bundle comprising a welded cylinder vessel manufactured of steel shells and equipped with at least one feed water supply connection pipe and one steam removal connection pipe, and two elliptical bottoms, vessel internals, inlet and outlet headers connected to the heat-exchange tube bundle forming a heat-exchange surface of the steam generator, wherein inner diameter dvess of the steam generator vessel is selected based on a formula.
Joint Stock Company "experimental And Design Organization "gidropress" Awarded The Order Of

Horizontal steam generator for a reactor plant with a water-cooled water-moderated power reactor and a reactor plant with the said steam generator

This invention relates to electric power industry, and more particularly to horizontal steam generators for nuclear power plants with a water-cooled water-moderated power reactor (vver) and to reactor plants with a vver reactor and a horizontal steam generator. A reactor plant with a vver reactor and a horizontal seam generator, including a nuclear reactor with four circulation loops, each comprising a steam generator with a horizontal bundle of heat-exchange tubes divided into banks by means of inter-tubular tunnels and connected to primary circuit coolant headers inside a cylindrical pressure vessel with elliptical bottoms, a reactor coolant pump, and a primary circuit coolant main circulation pipeline..
Aktsyonernoe Obshchestivo "ordena Trudovogo Krasnogo Znameni I Ordena Truda Chssr Opytnoe

Wind power generation system using airship

The present invention relates a wind power generation system using an airship, which can generate wind power using strong wind of a jet stream by using the airship, convert the wind power into a laser beam and transmit the laser beam to the ground so that power can be produced on the ground by converting the laser beam into electricity. The present invention provides efficiency and convenience in collecting power of the airship on the ground by implementing a wind power generation system using an airship to include: an airship for producing power through wind power generation while floating in the air and transmitting the produced power as a laser beam; and a ground receiving unit for receiving the laser beam transmitted.

Power generation system utilizing turbine arrays

A system for generating power from turbine arrays comprises a plurality of turbines positioned in a turbine array. Each turbine comprises a vertical shaft having an upper portion, a middle portion and a lower portion.

Anti-windmilling starter generator

An apu has a gas turbine engine and a starter generator to be selectively driven by the gas turbine engine. A sensor senses windmilling of components associated with the starter generator.
Hamilton Sundstrand Corporation

System and a gas turbine power generation system with a high pressure compressor with an added forward stage

The gas turbine power generation system includes a core engine and a low pressure compressor. The core engine includes a high pressure compressor, a combustor, and a high pressure turbine configured in a serial flow arrangement.
General Electric Company

Hydrogen generation and control for internal-combustion vehicle

A method of safely generating hydrogen gas for use in motor vehicles to increase the performance and decrease the emissions of the internal-combustion engine of the motor vehicle, and of controlling the safe generation and use of hydrogen gas in motor vehicles, using a hydrogen generator having close-spaced metal electrolysis plates in the generator housing, configured to inject hydrogen into the intake manifold or alternatively into the combustion chamber, and a control system monitoring and controlling gas level, liquid levels, temperature, pressure, flow rate, electric current, and tachometer, with monitoring and overriding control from the cab of the vehicle.. .

Non-replicative transduction particles and transduction particle-based reporter systems

Methods and systems are provided for packaging reporter nucleic acid molecules into non-replicative transduction particles for use as reporter molecules. The non-replicative transduction particles can be constructed from viruses and use viral transduction and replication systems.
Geneweave Biosciences, Inc.

Predicting productivity in early cell line development

The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: fkbp10, zdhhc6, myrip, actc1, ac124993.19, runx2, ac158560.4, plekhb1, rps6ka2, sept1, sprr2k, and flt1..
Lek Pharmaceuticals D.d.

Nlrc5 as a biomarker for cancer patients and a target for cancer therapy

The invention pertains to biomarkers for identifying a cancer that is likely or not likely to evade the immune system of a subject, thus, is likely or not likely to show better prognosis (prognostic biomarker) and/or better responses to cancer therapies (predictive biomarker). The invention provides a method of identifying a subject as having a cancer that is likely to evade the immune system of the subject based on one or more of the following biomarkers in the cancer cells of the subject: a) reduced amount of nlrc5 mrna or protein; b) reduced activity of nlrc5 protein; c) a mutation that reduces the activity of nlrc5 protein; d) increased methylation of nlrc5 or a portion thereof; and e) reduced copy number of nlrc5.
The Texas A&m University System

Non-invasive detection of fetal genetic traits

Blood plasma of pregnant women contains fetal and (generally >90%) maternal circulatory extracellular dna. Most of said fetal dna contains ≦500 base pairs, said maternal dna having a greater size.
Sequenom, Inc.

Reagent for detecting cross contamination of pdx-model related with human and mouse, the kit comprising the same, and the the cross contamination detection

Therefore, according to the present invention, cross contamination of genes related with the human and the mouse is predicted in advance to be applied to evaluation of anticancer drug efficacy using a patient-derived xenograft model or cell-derived xenograft model and contribute to cell banks using the patient-derived xenograft model or cell-derived xenograft model, and as a result, the present invention is very useful in a medical industry.. .

Epigenetic markers of pluripotency

Epigenetic methods for assessing pluripotentcy of a cell population, such as a stem cell culture are provided. For example, pluripotency can be assessed by determining dna methylation status at the rab25, nanog, ptpn6, mgmt, gbp3 and/or lyst gene regions.
Zymo Research Corporation

Noninvasive prenatal diagnostic methods

Prenatal genetic testing allows early detection of genetic disease in a fetus. Described herein are methods of detecting the presence or absence of a genetic variant in a region of interest in the genome of a fetus in a pregnant woman.
Counsyl, Inc.

Capsule array devices and methods of use

This disclosure provides microwell capsule array devices. The microwell capsule array devices are generally capable of performing one or more sample preparation operations.
10x Genomics, Inc.

Recombinant production of steviol glycosides

Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express recombinant genes encoding udp-glycosyltransferases (ugts). Such microorganisms, plants, or plant cells can produce steviol glycosides, e.g., rebaudioside a and/or rebaudioside d, which can be used as natural sweeteners in food products and dietary supplements..
Evolva Sa

Transformed fungus having enhanced ergothioneine productivity and producing ergothioneine

The purpose of the present invention is to provide an organism having an ergothioneine productivity that is capable of easily producing ergothioneine within a short period of time at a high yield, as compared with a conventional technology, and, therefore, enables ergothioneine production on an industrial scale. This purpose can be achieved by a transformed fungus into which a gene encoding enzyme (1) or genes encoding enzymes (1) and (2) have been inserted and in which the inserted gene(s) are overexpressed.
Kikkoman Corporation

Method for enhancing microbial methane produciton

A process for revitalization of the coal deposit for enhanced microbial gas production by exposing coal deposit to air oxidation. Water is removed from coal beds and stored.
United States Department Of The Interior

Yeast cells expressing tar dna-binding protein 43 and uses therefor

Disclosed are yeast cells expressing tar dna-binding protein 43 (tdp-43) and methods of screening yeast cells to identify compounds that prevent or suppress tdp-43-induced toxicity, compounds that inhibit the formation or maintenance of cytoplasmic inclusions of tdp-43, genetic suppressors or enhancers of tdp-43-induced toxicity, and genetic suppressors or enhancers of the formation or maintenance of cytoplasmic inclusions of tdp-43. Compounds identified by such screens can be used to treat or prevent tdp-43 proteinopathies such as frontotemporal lobar degeneration or amyotrophic lateral sclerosis..
Whitehead Institute For Biomedical Research

Dead guides for crispr transcription factors

The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are structural information on the cas protein of the crispr-cas system, use of this information in generating modified components of the crispr complex, vectors and vector systems which encode one or more components or modified components of a crispr complex, as well as methods for the design and use of such vectors and components.
Massachusetts Institute Of Technology

Variant forms of urate oxidase and use thereof

Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including pegylated proteins comprising truncated urate oxidase are described..
Horizon Pharma Rheumatology Llc

Co-differentiation of monocytes from allogeneic donors

Disclosed is a method of producing non-exhausted immature dendritic cells (dcs) originating front at two different, allogeneic donors. In the method, a mixture of allogeneic leukocytes, which allogeneic leukocytes have been obtained from at least two different, allogeneie donors is provided.
Immunicum Ab

Cd44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases

The present invention relates to compounds, pharmaceutical compositions and methods for treating different forms of cancer and angiogenesis related diseases using cyclic peptides.. .
Ruprecht-karls-universitÄt

Fragments of syndecan-2 having anti-angiogenic activity

The present invention provides an anti-angiogenic peptide comprising an amino acid sequence having at least 70% identity to amino acid residues 123-140 of seq id no 1 or amino acid residues 24-141 of seq id no 2. The invention also provides nucleic acid constructs encoding such peptides, and vectors and cells comprising such nucleic acid constructs.
Queen Mary University Of London

Function suppression type of genetically-modified rhodocytin mutant

According to the present invention, a mutant rhodocytin lacking platelet aggregation ability is provided. According to the present invention, a pharmaceutical composition including a mutant rhodocytin lacking platelet aggregation ability is provided.
University Of Yamanashi

Protein m related immunoglobulin-binding polypeptides

The invention relates to a group of isolated polypeptides and derivatives that can bind genetically to immunoglobulins or antibodies. The invention also relates to industrial and other applications of these molecules, e.g., antibody purifications..
The Scripps Research Institute

Cortistatin analogues and syntheses thereof

And salts thereof, wherein r1, r2, r3, r4, n, and m are as defined herein; processes for preparing such compounds and intermediates thereto; pharmaceutical compositions comprising such compounds; methods for treating a proliferative disease; methods for treating a disease associated with aberrant angiogenesis; methods for inhibiting angiogenesis; and processes for preparing cortistatin a, j, k, and l, and analogs thereof.. .

Method for preparation of fluoro, chloro and fluorochloro alkylated compounds by homogeneous catalysis

The invention discloses a method for preparation of fluoro, chloro and fluorochloro alkylated compounds by homogeneous pd catalyzed fluoro, chloro and fluorochloro alkylation with fluoro, chloro and fluorochloroalkyl halides in the presence of di(1-adamantyl)-n-butylphosphine and in the presence of 2,2,6,6-tetramethylpiperidine 1-oxyl.. .
Lonza Ltd

Compositions and methods of treating retinal disease

Compositions and methods for treating macular degeneration and other forms of retinal disease whose etiology involves the accumulation of a2e and/or lipofuscin, and, more specifically, for preventing the formation and/or accumulation of a2e are disclosed. .
Aldeyra Therapeutics, Inc.

Inhibitors of histone demethylases

The present application discloses compounds capable of modulating the activity of histone demethylases (hdmes), which are useful for prevention and/or treatment of diseases in which genomic dysregulation is involved in the pathogenesis, such as e.g. Cancer.
Gilead Science, Inc.

Improved process for the reductive amination of halogen-containing substrates

Disclosed is a process for performing a reductive amination of a first functional group in an organic feed substrate, which feed substrate comprises at least one further functional group containing a halogen atom, wherein the halogen atom is selected from the list consisting of chlorine, bromine, iodine, and combinations thereof, in the presence of hydrogen and a heterogeneous catalyst comprising at least one metal from the list of pd, pt, rh, ir, and ru, and in absence of any catalytic amount of any second metal from the list consisting of ag, ni, co, sn, bi, cu, au, and combinations thereof. The process is preferably applied for the reductive amination of 2-chloro-benzaldehyde to form 2-chloro-benzyldimethylamine, as an intermediate in the production of active agrochemical compounds and microbicides of the methoximinophenylglyoxylic ester series..
Taminco Bvba

One-pot process using heterogeneous catalyst

The present invention relates to a process for the one-pot hydrogenation and dehydration or isomerization of an organic compound, and to a catalyst composition for this process comprising transition metal particles having particle size below 50 nm supported on a material comprising at least one fluorinated polymer (p), wherein polymer (p) bears —so2x functional groups, x being selected from x′ and om, x′ being selected from the groups consisting of f, cl, br and i; and m being selected from the group consisting of h, and alkaline metal and nh4.. .
Solvay Specialty Polymers Italy S.p.a.

Systems and methods for fluid treatment with homogeneous distribution of ultraviolet light

In various embodiments, a fluid is treated by flowing the fluid through a flow cell having (i) a fluid entry, (ii) a fluid exit, (iii) a treatment region disposed between the fluid entry and exit, and (iv) an interior surface reflective to ultraviolet (uv) light, and diffusively reflecting uv light emitted from one or more uv light sources to illuminate the treatment region substantially uniformly, thereby treating the fluid.. .

Conveyance system for operation in radioactive environment

A system for manufacturing radionuclide generators includes an enclosure defining a radioactive environment. The enclosure includes radiation shielding to prevent radiation within the radioactive environment from moving to an exterior of the enclosure.
Mallinckrodt Nuclear Medicine Llc

Fuel efficiency of road vehicles

An aerodynamic unit is configured for attachment onto a roof of a road vehicle, so that air passes over the unit during forward movement of the road vehicle. The unit has a first end for positioning distal to a rear end of a vehicle roof, and a second end for positioning proximal a rear end of a vehicle roof.

Methods and system for mitigating undesirable conditions during regenerative braking

Systems and methods for operating a transmission of a hybrid powertrain that includes a motor/generator are described. The systems and methods may classify transmission degradation in response to an estimated transmission input shaft speed that is determined from transmission output shaft speed.
Ford Global Technologies, Llc

Control of engine pulse torque cancellation commands

A powertrain assembly includes a transmission, an engine, first and second motor/generators and a controller. The controller includes a processor and memory on which is recorded instructions for executing a method for controlling engine pulse torque cancellation commands.
Gm Global Technology Operations Llc

Apparatus for generating electrical pulses and methods of using the same

A method and apparatus are provided for delivering an agent into a cell through the application of nanosecond pulse electric fields (“nspef's”). The method includes circuitry for delivery of an agent into a cell via known methods followed by the application of nanosecond pulse electric fields to said cell in order to facilitate entry of the agent into the nucleus of the cell.
Old Dominion University Research Foundation

Pump for operation in radioactive environment

A system for manufacturing radionuclide generators includes an enclosure defining a radioactive environment. The enclosure includes radiation shielding to prevent radiation within the radioactive environment from moving to an exterior of the enclosure.
Mallinckrodt Nuclear Medicine Llc

Composite polymeric nanofibers for skin regeneration

A method for preparing a skin regeneration scaffold is disclosed. The method may include preparing a polymer solution by dissolving a biopolymer in a solvent, and subjecting the polymer solution to a template-assisted extrusion process with a nanoporous material as a template in order to produce polymer nanofibers.

Alimentary protein-based scaffolds (aps) for wound healing, regenerative medicine and drug discovery

The invention provides engineered biomaterials derived from plant products. The engineered biomaterials are useful for biomedical applications.
Drexel University

Bioactive wound dressing and teeth coating based on morphogenetically active amorphous calcium polyphosphate

This invention relates to a method for sealing dentinal tubules exposed at the tooth surface as a consequence of enamel defects, based on amorphous calcium polyphosphate (ca-polyp) nano- or microparticles that strongly bind both to tooth enamel, cementum and dentin surfaces. The inventive method can also be used for the production of morphogenetically active tooth implants.
Nanotecmarin Gmbh

Compositions for wound treatment

A wound dressing composition comprising a chitosan and an oxidized cellulose. For example, the composition may be in the form of a sponge formed by freeze drying an aqueous dispersion of chitosan and oxidized regenerated cellulose (orc).
Kci Usa, Inc.

System and method to modulate pain and itch through cutaneous transfer of genetic information

One embodiment is directed to a method for altering the function of the sensory unit that innervates a targeted tissue region in a mammal comprising the steps of identifying the targeted tissue region; cutaneously administering into the targeted tissue region an adeno-associated virus wherein the viral genome encodes at least one exogenous protein; expressing the exogenous protein in the targeted sensory unit; and altering the function of the targeted sensory unit to treat or restore the sensory response because of the exogenous protein expression while not impacting the function of nearby sensory units.. .
Circuit Therapeutics, Inc.

System and method to modulate pain and itch through cutaneous transfer of genetic information

One embodiment is directed to a system for altering the function of a sensory unit that innervates a targeted tissue region in an animal, the sensory unit being configured to express a light-responsive protein, comprising a light delivery element configured to direct radiation to at least a portion of a targeted tissue structure; and a light source configured to provide light to the light delivery element; wherein the targeted tissue structure is illuminated transcutaneously with radiation such that a membrane potential of cells comprising the targeted tissue structure is modulated at least in part due to exposure of the light-responsive protein to the radiation.. .
Circuit Therapeutics, Inc.

Methods of selecting t cell line and donor thereof for adoptive cellular therapy

Disclosed herein are methods of selecting an allogeneic t cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer. Also disclosed are methods of selecting a donor from whom to derive an allogeneic t cell line for therapeutic administration to a patient having or suspected of having a pathogen or cancer..
Memorial Sloan Kettering Cancer Center

Use of antibodies for enrichment of engineered t cells with exogenous immune receptors and antibodies for use in depletion of engineered t cells

The current application provides for exogenous immune receptors that do not require any additional selection marker genes and/or any additional silicide genes. The disclosure allows for the production of engineered t cells that can be enriched for in an untouched manner, i.e., the engineered t cells do not require any interaction with any outside agent and can be selected for by eliminating t cells that express the endogenous alpha beta t cell receptor.
Umc Utrecht Holding B.v.

Mhc-i restricted epitopes containing non-natural amino acid residues

The invention provides for the synthesis of more effective generators of a t-cell immune response by providing peptide derivatives that are mhc class i-restricted antigens. The peptide derivatives of the present invention are prepared or derived from a parent peptide of 8 to 11 amino acid residues in length, wherein the peptide derivative contains a non-natural amino acid substituted in place of a naturally-occurring amino acid residue at one or more primary anchor positions in the parent peptide or at position 6, position 7, or the c-terminus..
Purdue Pharma L.p.

Prevention and treatment of infections

The invention relates to the use of il-22 in prevention and therapy of infections in particular related to viral infections in individuals who are unable to respond to viral exposure with enhanced il-22 gene expression or protein production.. .
Immunoclin Limited

Maspin-based inhibition of osteoclast activity and promotion of bone formation

Provided herein are compositions and methods for the treatment of bone disorders through the maspin-based inhibition of osteoclastogenesis and osteoclast activity and the promotion of bone formation.. .
Northwestern University

Stable neural stem cells comprising an exogenous polynucleotide coding for a growth factor and methods of use thereof

The present disclosure provides a human neural stem cell comprising an exogenous polynucleotide coding for a growth factor such as igf-1. Also disclosed are methods of using the human neural stem cells for the treatment of neurodegenerative diseases or disorders including, for example, als..
Neuralstem, Inc.

Multipotent stem cells and uses thereof

The invention provides a quiescent stem cell having the capacity to differentiate into ectoderm, mesoderm and endoderm, and which does not express cell surface markers including mhc class i, mhc class ii, cd44, cd45, cd13, cd34, cd49c, cd73, cd105 and cd90. The invention further provides a proliferative stem cell, which expresses genes including oct-4, nanog, sox2, gdf3, p16ink4, bmi, notch, hdac4, tert, rex-1 and twist but does not express cell surface markers including mhc class i, mhc class ii, cd44, cd45, cd13, cd34, cd49c, cd73, cd105 and cd90.
The Brigham And Women's Hospital, Inc.

Means and methods for treatment of early-onset parkinson's disease

This application relates to the field of neurodegenerative diseases, more particularly to the field of parkinson's disease. In particular, the disclosure describes that inhibitors reducing fas activity can be used for treatment of parkinson's disease, in particular, the treatment of patients suffering from parkinson's disease having loss of function mutations in pink1 or parkin genes..
Katholieke Universiteit Leuven, K.u.leuven R&d

Compositions and methods for treating ocular diseases

Disclosed herein are compositions and methods for treating ocular diseases, inter alia, diabetic macular edema, age-related macular degeneration (wet form), choroidal neovascularization, diabetic retinopathy, retinal vein occlusion (central or branch), ocular trauma, surgery induced edema, surgery induced neovascularization, cystoid macular edema, ocular ischemia, uveitis, and the like. These diseases or conditions are characterized by changes in the ocular vasculature whether progressive or non-progressive, whether a result of an acute disease or condition, or a chronic disease or condition..
Aerpio Therapeutics, Inc.

Use of metal-organic framework as tumor angiogenesis inhibitor

The invention relates to the field of metal-organic framework materials and the field of medical technology, relates to a method for inhibiting tumor angiogenesis or preventing and/or treating tumor, comprising administering to a subject in need thereof an effective amount of a metal-organic framework comprising fe and ligand. The invention further relates to a method for inhibiting the expression of matrix metalloproteinase in a cell, comprising administering to the cell an effective amount of a metal-organic framework comprising fe and ligand..
Yunnan University

Aldose reductase inhibitors and uses thereof

The present invention relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention. Other disorders can include, but are not limited to, atherosclerosis, coronary artery disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy, infections of the skin, peripheral vascular disease, stroke, and the like..
The Trustees Of Columbia University In The City Of New York

Compounds and their use as bace inhibitors

The present invention relates to compounds of formula (i) and their pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of aβ-related pathologies such as down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to mci (“mild cognitive impairment”), alzheimer's disease, memory loss, attention deficit symptoms associated with alzheimer's disease, neurodegeneration associated with diseases such as alzheimer's disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with parkinson's disease, progressive supranuclear palsy or cortical basal degeneration..
Astrazeneca Ab

Use of ccr3-inhibitors

For use as a medicament for the treatment of diseases selected from dry age-related macular degeneration (damd), wet age-related macular degeneration (wamd), retinopathy of prematurity (rop), central retinal vein occlusion (crvo), nasal polyposis, eosinophilic esophagitis, eosinophillic gastroenteritis (e.g. Eosinophilic gastritis and eosinophilic ententeritis), hypereosinophilic syndrome and churg strauss syndrome..

Salinosporamides and methods of use thereof

The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains cnb392 and cnb476 are effective inhibitors of hyperproliferative mammalian cells. The cnb392 and cnb476 strains lie within the family micromonosporaceae, and the generic epithet salinospora has been proposed for this obligate marine group.
The Regents Of The University Of California

Composition and treating neuronal ceroid lipofuscinosis

Provided herein are methods for treatment of a neurodegenerative disease, such as neuronal ceroid lipofuscinosis including administering to a subject in need of such treatment a composition comprising a therapeutically effective amount of an agent that mediates upregulation of tpp1.. .
Rush University Medical Center

Enterically coated cysteamine, cystamine and derivatives thereof

The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects..
The Regents Of The University Of California

Enterically coated cysteamine, cystamine and derivatives thereof

The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects..
The Regents Of The University Of California

Enterically coated cysteamine, cystamine and derivatives thereof

The disclosure provides oral cysteamine and cystamine formulations useful for treating cystinosis and neurodegenerative diseases and disorders. The formulations provide controlled release compositions that improve quality of life and reduced side-effects..
The Regents Of The University Of California

Self-assembled gels for controlled delivery of biologics and labile agents

Gels are formed based on generally recognized as safe (gras) low molecular weight amphiphilic molecules in a self-assembly process with limited or no heating. A selective range of ratios between an organic solvent and water, or an aqueous solution, in the medium, allows for the gras low molecular weight amphiphiles to form a homogeneous self-supporting gel encapsulating agents to be delivered under very mild conditions.
The Brigham And Women's Hospital, Inc.

Self assembled gels for controlled delivery of encapsulated agents to cartilage

A self-assembled gel composition with enhanced adhesion to cartilage tissue is provided. A cationic agent co-self assembles with a generally regarded as safe (gras), low molecular weight (<2,500 da) gelator, forming homogeneous self-supporting gel that can encapsulate one or more therapeutic agents for controlled release.
The Brigham And Women's Hospital, Inc.

Morphogenetically active amorphous calcium polyphosphate nanoparticles containing retinol for therapeutic applications

This invention concerns a calcium polyphosphate material consisting of amorphous nanoparticles with a diameter of approximately between about 45 nm to about 0.25 μm that displays a considerable hardness (elastic modulus) of about 1.3 gpa. The inventive noncrystalline and biodegradable material that is produced under mild conditions, at room temperature, is morphogenetically active and preferably induces bone formation and the expression of the marker gene for osteoblast activity, alkaline phosphatase.
Nanotecmarin Gmbh

Topsheets integrated with heterogenous mass layer

An absorbent article and method of making the absorbent article are disclosed. The absorbent article having a topsheet, a backsheet, and an absorbent core structure having one or more layers wherein at least one layer is a heterogeneous mass layer, wherein the topsheet and the heterogeneous mass are integrated such that they reside in the same x-y plane..
The Procter & Gamble Company

Topsheets integrated with heterogenous mass layer

An absorbent article and method of making the absorbent article are disclosed. The absorbent article having a topsheet, a backsheet, and an absorbent core structure having one or more layers wherein at least one layer is a heterogeneous mass layer, wherein the topsheet and the heterogeneous mass are integrated such that they reside in the same x-y plane..
The Procter & Gamble Company

Topsheets integrated with heterogenous mass layer

An absorbent article and method of making the absorbent article are disclosed. The absorbent article having a topsheet, a backsheet, and an absorbent core structure having one or more layers wherein at least one layer is a heterogeneous mass layer, wherein the topsheet and the heterogeneous mass are integrated such that they reside in the same x-y plane..
The Procter & Gamble Company

Topsheets integrated with heterogenous mass layer

An absorbent article and method of making the absorbent article are disclosed. The absorbent article having a topsheet, a backsheet, and an absorbent core structure having one or more layers wherein at least one layer is a heterogeneous mass layer, wherein the topsheet and the heterogeneous mass are integrated such that they reside in the same x-y plane..
The Procter & Gamble Company

Hydrogen peroxide-producing bacterial composition

The invention provides compositions that include isolated, non-pathogenic, hydrogen peroxide-producing bacterial strains and genetically engineered ldh-deficient bacterial strains, which can be used to whiten teeth and treat periodontal disease.. .
Probiora Health, Llc

Beverage container coaster

A beverage container coaster with a coaster housing having a substantially horizontal palm portion that contains a beverage area for supporting a beverage container in a substantially level fashion. At least one finger extension is attached to said coaster housing.

Display stand

A portable and self stabilizing stand which can display a wide array of objects and which can be expanded or contracted by the user to accommodate a large array of object types and sizes. The stand is easily assembled and disassembled without requiring specialized or generic tools or fasteners..

Headgear safety apparatus

This invention relates generally to the field of headgear, and, more particularly, to a headgear safety apparatus in the form of a single contiguous and homogeneous pad, having an inner surface, wherein said inner surface is substantially concave; an outer surface, wherein said outer surface is substantially convex; and a one or more safety features. The single contiguous and homogeneous pad is manufactured from closed-cell, ethylene vinyl acetate foam using an injection molding process to create integrated safety features in a single, anti-microbial, safety pad that protects the wearer but does not cover the ears..
Ldr Headgear, Llc

Increased salt perception in processed food by inhomogeneous sodium distribution

The present invention relates to a method and resulting food composition for reducing sodium in food products without impacting the salty taste of said food products. In particular, the present invention pertains to a method of producing a food composition, the method comprising the steps of: gelling a non-starch hydrocolloid polymer in an aqueous food matrix; cooling the food matrix comprising the jellified hydrocolloid polymer; and adding sodium to the cooled food matrix to form the food composition..
Nestec S.a.

Methods of controlling fructan synthesis in plants

The present invention relates to plants with increased levels of water soluble carbohydrates, particularly fructan, in the stem and leaf sheath. The present invention also provides methods of identifying and/or producing these plants.
Commonwealth Scientific And Industrial Research Organisation

Frozen tea treat with non-synthetic ingredients and making the same

The invention relates to ice lollys comprising a frozen liquid tea based composition comprising: water, tea powder or tea concentrate, methyl glucoside coconut oil ester, guar, gellan or pectin gum, and usda certified organic non-genetically modified organism (non-gmo) grown fruit or vegetables in the form of a concentrate of liquid, puree, or powder. The processing and subsequent packaging allows the composition to be processed without heating and/or pasteurization but remain shelf stable in the frozen form..

Inbred corn line cb20

Inbred corn lines, designated bb202, ab8, ab18, ab19, bb84, bb85, bb95, bb98, bb201, bc106, bc137, cb20, or mn26, are disclosed. The invention relates to the seeds of inbred corn line bb202, ab8, ab18, ab19, bb84, bb85, bb95, bb98, bb201, bc106, bc137, cb20, or mn26, to the plants and plant parts of inbred corn line bb202, ab8, ab18, ab19, bb84, bb85, bb95, bb98, bb201, bc106, bc137, cb20, or mn26 and to methods for producing a corn plant, either inbred or hybrid, by crossing inbred corn line bb202, ab8, ab18, ab19, bb84, bb85, bb95, bb98, bb201, bc106, bc137, cb20, or mn26 with itself or another corn line.
Kws Saat Se

Microelectromechanical systems (mems) microphone bias voltage

Microelectromechanical systems (mems) sensors and related bias voltage techniques are described. Exemplary mems sensors, such as exemplary mems acoustic sensors or microphones described herein can employ one or more bias voltage generators and single-ended or differential amplifier arrangements.

Accessory and mobile computing device communication using an application communication protocol

Embodiments of the present invention provide various communication techniques for communication between a mobile computing device and an accessory. An accessory protocol that is generic to the mobile computing device can be used for some communication.

Event correlation across heterogeneous operations

Methods, systems, and apparatus, including computer programs encoded on computer storage media, for determining a network security threat response. A data structure that represents communication events between computing devices of two or more network domains is received.

Methods for operating a separate power supply system

A method for operating an electrical charging station at an electrical grid comprising, alongside electrical loads, at least one regenerative energy generator, at least one conventional generator operated by fossil fuels, and at least the electrical charging station for storing and re-emitting electrical power, wherein the charging station is controlled in such a way that the feed-in power is limited in terms of its change over time.. .

Resiliency controller for voltage regulation in microgrids

A computer-implemented method for controlling voltage fluctuations of a microgrid including a plurality of distributed generators (dgs) is presented. The computer-implemented method includes collecting, by a resiliency controller including at least a voltage control module, measurement data from the microgrid, using, by a reactive power estimator, reactive power estimations to calculate an amount of reactive power for each of the dgs, and using a dynamic droop control unit to distribute the reactive power to each of the dgs of the microgrid..

Flexible thermoelectric generator and methods of manufacturing

Flexible thermoelectric generators and methods of manufacturing are disclosed. In one embodiment, a flexible thermoelectric generator includes a plurality of pillars, a first and a second plurality of flexible interconnects, and a flexible material.

Semiconductor device having heterogeneous structure and forming the same

A semiconductor device is provided as follows. A first buffer layer is disposed on a substrate including nmos and pmos regions.

Method for manufacturing semiconductor device, ion beam etching device, and control device

An ion beam etching device includes a grid provided between a treatment chamber and a plasma generation chamber, and for forming an ion beam by drawing ions from the plasma generation chamber; a gas introduction unit for introducing discharge gas into the plasma generation chamber; an exhaust for exhausting the treatment chamber; a substrate holder; a control unit to receive a measurement result of an in-plane film thickness distribution before the substrate is processed; and an electromagnetic coil provided outside of the plasma generation chamber in a ceiling portion opposite to the grid of the plasma generation chamber. The electromagnetic coil includes an outer coil provided on an outer circumference of the ceiling portion and an inner coil provided on an inner circumference of the ceiling portion, and the control unit controls the currents applied to the outer coil and the inner coil in accordance with the measurement result..

Emerging defect and safety surveillance system

Described is a system for identifying emerging trends in a consumer product from heterogeneous online data sources. Data extracted from heterogeneous data sources is fused, and consumer product data is identified from the fused data.

Fingerprint sensing device with heterogeneous coating structure comprising a dielectric material

The invention relates to a fingerprint sensing device comprising a sensing chip comprising an array of capacitive sensing elements. The sensing device comprises a coating material arranged in a layer on top of the array of sensing elements and comprising a plurality of cavities filled with a dielectric material.

Analog heterogeneous connectivity tags and methods and systems to configure the tags

Analog heterogeneous tags and methods and systems to configure the tags are described. The present invention relates to the field of electronic devices and more particularly to electronic tag devices using analog technology.

Information processing device, information processing method, program and information processing system

[object] it is desirable to realize a more efficient coordination between the genetic analysis company and the medical institution. [solution] provided is an information processing device including: a data acquisition unit configured to acquire predetermined information; a determination unit configured to determine whether or not personal information of a subject has been set in the predetermined information; and an identification information provision unit configured to provide a medical institution terminal with user identification information required when the subject uses a service, in a case where it is determined that the personal information of the subject has not been set in the predetermined information..

Method to identify genes under positive selection

A method and computer system for identifying genes associated with a phenotype includes obtaining data representing mutations in a cohort of subjects exhibiting a phenotype. An evolutionary action (ea) score is calculated for each mutation using the data obtained.

Generalized jet-effect

The invention provides a method for computational fluid dynamics and apparatuses making enable an efficient implementation and use of an enhanced jet-effect, either the coanda-jet-effect, the hydrophobic jet-effect, or the waving-jet-effect, triggered by specifically shaped corpuses and tunnels. The method is based on the approaches of the kinetic theory of matter, thermodynamics, and continuum mechanics, providing generalized equations of fluid motion.

Method for generating a petri net simulation model of an industrial control system

A computer implemented method generates a petri net simulation model of an industrial controls system. The method includes providing a basic petri net system model employing a generic component model.

Semantic diff and automerge

Resolving conflicting changes to structured data files. A method includes for a structured data file which has both a generic structure and dialects built on top of the generic structure, for which conflicting changes have been made, and where an original version of the structured data, a first version of the structured data and a second version of the structured data exist, determining a dialect of the structured data.

Integrated heterogeneous processing units

According to an example, an instruction to run a kernel of an application on an apparatus having a first processing unit integrated with a second processing unit may be received. In addition, an application profile for the application at a runtime of the application kernel on the second processing unit may be created, in which the application profile identifies an affinity of the application kernel to be run on either the first processing unit or the second processing unit, and identifies a characterization of an input data set of the application.

Task scheduling method and apparatus on heterogeneous multi-core reconfigurable computing platform

Embodiments of the present invention provide a task scheduling method and apparatus on a heterogeneous multi-core reconfigurable computing platform. The method includes: when determining that a to-be-executed hardware task is in a ready state, adding the to-be-executed hardware task into a target hardware task queue corresponding to a function of the to-be-executed hardware task; reconfiguring, according to a priority of the to-be-executed hardware task and a usage status of multiple reconfigurable resource packages, at least one reconfigurable resource package in the multiple reconfigurable resource packages into a target intellectual property ip core that can execute the to-be-executed hardware task.

Watch display using light sources with a translucent cover

A display assembly includes a display selectively displaying human-readable indicia on a face thereof and a cover disposed over the display. The cover has a homogeneous surface over the entire face of the display.

Amyloid binding agents

There are provided compounds and methods for the detection of amyloids and treatment of diseases related to amyloids including alzheimer's disease and other related amyloid-based neurodegenerative diseases.. .

Novel tissue protective erythropoietin receptor (nepor) and methods of use

There is disclosed a molecular composition(s) of a novel tissue protective erythropoietin (epo) binding receptor protein complex, termed nepor. Presence of nepor components on a tumour allows epo to impinge on the survival of associated cells thereby enhancing tumour progression and negatively effecting patient survival.

Auto-fill two-layer two-half wear resistant elbow of concrete pump truck and manufacturing method thereof

An auto-fill two-layer two-half wear resistant elbow of a concrete pump truck consists of an outer-layer protection elbow, an inner-layer heterogeneous wear resistant combined elbow and a wear resistant connecting flange. A filling space is provided between the outer-layer protection elbow and the inner-layer heterogeneous wear resistant combined elbow.

Method for operating a wind power plant in a weak grid environment and a wind power plant

In various embodiments of the present disclosure, there is provided a method of operating a wind power plant in a weak grid environment in order to achieve desired system stability criteria and to support an electrical grid during small disturbances or faults, the wind power plant being coupled to an electrical grid, and including a power plant controller for controlling a plurality of wind turbine generators of the wind power plant, the method including: determining whether the electrical grid fulfils a weak grid criterion; setting the power plant controller to operate in a weak grid mode when the weak grid criterion is fulfilled, the weak grid mode including: reducing and providing an active power reference according to which the plurality of wind turbine generators are controlled, when a grid voltage deviates beyond a threshold voltage from a normal or recommended operating voltage range during steady state operation of a wind power plant; and generating a reduced amount of active power with each of the plurality of wind turbine generators based on the provided active power reference& controlling the active power ramp rates, when the electrical grid recovers from the voltage deviation or a fault. A corresponding wind power plant is further provided.

Thermodynamically interactive heat flow process and multi-stage micro power plant

A high efficiency, thermodynamically interactive power system incorporating a “thermodynamic battery” operating in the cryogenic range. The “thermodynamic battery” is drawn upon to optimize the efficiency of power generation during times of peak demand and is “recharged” during periods of low demand.

Methods and systems for an engine after-treatment system

The present subject matter relates to a method and a treatment system monitor for monitoring an engine exhaust after-treatment system containing more than one lean nox traps (lnt). The method includes receiving an exhaust gas of a desired air-fuel ratio upstream of a respective lnt.

Engine exhaust and cooling system for power production

He is disclosed a heat scavenging system for recapturing waste heat from an internal combustion engine having a water cooling system and an exhaust system. The heat scavenging system includes a first cooling stream coupled to the exhaust system for transferring heat from the exhaust system and converting it into a first high pressure gas stream for driving a first turbine coupled to a first electric generator.

Construction tidal power generation system capable of multiple-flow power generation from installation of uniflow generator

The present invention relates to a construction method for a tidal power generation system capable of multiple-flow power generation from an installation of a uniflow generator, and more particularly, to a construction method for a tidal power generation system, in which auxiliary waterways are installed at both sides of a hydraulic turbine waterway in which the uniflow generator is installed, respectively, such that water is introduced into one side auxiliary waterway so as to generate power, and the other side auxiliary waterway is connected to an existing drain waterway so that the water used to generate power may be drained, thereby enabling the multiple-flow power generation only by opening and closing a required sluice gate.. .

Seawater electrolysis hydrogen recovery and power generation system

A seawater electrolysis hydrogen recovery and power generation system is capable of recovering hydrogen gas and using the hydrogen gas to drive an electric turbine generator during the operation of a seawater electrolyzer for production of sodium hypochlorite. The seawater electrolysis hydrogen recovery and power generation system includes pipelines, booster pumps, a plenum chamber and a condenser chamber..

Predicting genetically stable recombinant protein production in early cell line development

The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: hist1h2bc, egrl, bx842664.2/hist 1h3c, dhfr, fgfr2, ac115880.11, mmp10, vsnll (optional), cu459186.17, el 30203 b14rik, cspg4, c1qtnf1, foxp2, and ptpre..

Microfluidic device for detecting target gene, manufacturing same, and detecting using same

The present invention provides facile and accurate molecular diagnosis of disease-specific genes capable of the naked eye detection through amplifying the target genes to selectively block the fluid path in a microfluidic device. Specifically, the present invention includes an isothermal amplification of target genes through a rolling circle amplification, a microfluidic device for detecting pathogen genes, and a detection method using the same.

Enzymatic one-pot reaction for double polypeptide conjugation in a single step

Herein is reported a method for producing an enzymatic conjugation product of three polypeptides comprising the simultaneous incubation of i) a first polypeptide comprising the amino acid sequence lpxtg (seq id no: 20, wherein x can be any amino acid residue), a second polypeptide comprising the amino acid sequence lpxta (seq id no: 31, wherein x can be any amino acid residue), a third polypeptide that has two n-termini whereby the polypeptide has an oligo-glycine gm (m=2 (seq id no: 22), or 3 (seq id no: 23), or 4 (seq id no: 24), or 5 (seq id no: 25)) amino acid sequence at its first n-terminus and an oligo-alanine am (m=2 (seq id no: 26), or 3 (seq id no: 27), or 4 (seq id no: 28), or 5 (seq id no: 29)) amino acid sequence at its second n-terminus, a fourth polypeptide with sortase activity whereby the polypeptide is derived from staphylococcus aureus sortase a, and a fifth polypeptide with sortase activity whereby the polypeptide is derived from streptococcus pyogenes sortase a and the recovering of the conjugate from the reaction mixture.. .

A sucrose phosphorylase for the production of kojibiose

The present invention relates to the production of the disaccharide kojibiose which is known to be a powerful prebiotic. The invention indeed discloses the generation of genetically modified sucrose phosphorylases which convert—via a transglycosylation reaction—sucrose into kojibiose in a very efficient manner.

Genetically modified msc and therapeutic methods

This disclosure relates to vectors, isolated cells, compositions, and methods for the treatment of critical limb ischemia and associated disorders. One aspect of the disclosure relates to a vector comprising a nucleic acid encoding a 165a isoform vegf protein and a promoter that regulates expression of the nucleic acid encoding the vegf..

Phytophthora resistant plants belonging to the solanaceae family

The present invention relates to a plant belonging to the solanaceae family wherein said plant comprises a genetic trait providing phytophthora resistance and wherein said resistance trait is encoded by a combination of at least two genes having a reduced expression, or transcription, of said genes or a reduced activity of proteins encoded by said genes as compared to said plant belonging to solanaceae family being susceptible to phytophthora. The present invention especially relates to plants belonging to the solanaceae family selected from the group consisting of sweet pepper (capsicum annuum), capsicum spp., potato (solanum tuberosum), petunia, tomato (solanum lycopersicum), nicotinia benthamiana, and tabacco (nicotinia tabacum), and the present phytophthora resistance is especially a resistance to a plant pathogen selected from the group consisting of phytophthora spp., phytophthora capsici, phytophthora infestans, and phytophthora nicotinae..

Optimized thionin protects plants against bacterial infections

Two small proteins with anti-bacterial activity are generated and called optimized thionin and optimized pro-thionin. Optimized pro-thionin contains a signal sequence for intracellular trafficking of the protein and is cleaved off to yield optimized thionin.

Wheat with increased resistant starch levels

A series of independent human-induced non-transgenic mutations found at one or more of the sbeii genes of wheat; wheat plants having these mutations in one or more of their sbeii genes; and a method of creating and finding similar and/or additional mutations of sbeii by screening pooled and/or individual wheat plants. The seeds and flour from the wheat plants of the present invention exhibit an increase in amylose and resistant starch without having the inclusion of foreign nucleic acids in their genomes.

Wheat with increased resistant starch levels

A series of independent human-induced non-transgenic mutations found at one or more of the sbeii genes of wheat; wheat plants having these mutations in one or more of their sbeii genes; and a method of creating and finding similar and/or additional mutations of sbeii by screening pooled and/or individual wheat plants. The seeds and flour from the wheat plants of the present invention exhibit an increase in amylose and resistant starch without having the inclusion of foreign nucleic acids in their genomes.

Herbicide-resistant taraxacum kok-saghyz and taraxacum brevicorniculatum

The invention provides the genetically manipulated herbicide-resistant rubber producing dandelion plants and seed of said plants. Another aspect of the invention comprises progeny plants, or seeds, or regenerable parts of plants and seeds of the genetically manipulated herbicide-resistant dandelion plants.

Compact and optimized metabolic pathway design in pichia pastoris

The present invention relates to an optimized metabolic pathway design in p. Pastoris.

Modified tgf-beta oligonucleotide for use in a preventing and/or treating an ophthalmic disease

The invention refers to an oligonucleotide consisting of 10 to 20 nucleotides of selected regions of the tgf-beta1, tgf-beta2 or tgf-beta3 nucleic acid sequence, which comprises modified nucleotides such as lna, ena, polyalkylene oxide-, 2′-fluoro, 2′-o-methoxy and/or 2′-o-methyl modified nucleotides. The invention further relates to pharmaceutical compositions comprising such oligonucleotide, wherein the composition or the oligonucleotide is used in a method for the prevention and/or treatment of glaucoma, posterior capsular opacification, dry eye, marfan or loeys-dietz syndrome, riboblastoma, choroidcarcinoma, macular degeneration, such as age-related macular degeneration, diabetic macular endma, or cataract..

Microrna-200 based approaches for modulating bone formation inhibition and bone regeneration

In certain embodiments, the present invention provides the use of microrna (mir)-200a and/or mir-200c to inhibit ossification and bone formation. In certain embodiments, the present invention provides the use of mir-200a inhibitor to stimulate bone regeneration..

Methods for genome assembly, haplotype phasing, and target independent nucleic acid detection

The disclosure provides methods to assemble genomes of eukaryotic or prokaryotic organisms. The disclosure provides methods for haplotype phasing and meta-genomics assemblies.

Variant forms of urate oxidase and use thereof

Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including pegylated proteins comprising truncated urate oxidase are described..

Variant forms of urate oxidase and use thereof

Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including pegylated proteins comprising truncated urate oxidase are described..

Variant forms of urate oxidase and use thereof

Genetically modified proteins with uricolytic activity are described. Proteins comprising truncated urate oxidases and methods for producing them, including pegylated proteins comprising truncated urate oxidase are described..

Multipotent stem cells and uses thereof

The invention provides a quiescent stem cell having the capacity to differentiate into ectoderm, mesoderm and endoderm, and which does not express cell surface markers including mhc class i, mhc class ii, cd44, cd45, cd13, cd34, cd49c, cd73, cd105, cd90, cd66a, cd66e, cxcr4, cd133 or an ssea. The invention further provides a proliferative stem cell, which expresses genes including oct-4, nanog, sox2, gdf3, p16ink4, bmi, notch, hdac4, tert, rex-1, twist, klf-4 and stella but does not express cell surface markers including mhc class i, mhc class ii, cd44, cd45, cd13, cf34, cf49c, cd73, cd105, cd90, cd66a, cd66e, cxcr4, cd133 or an ssea.

Radial bed reactor allowing the use of a small quantity of catalyst

The present invention describes a type of radial bed reactor which can allow a small quantity of catalyst to be used. Application to a regenerative reforming process reactor..

Pressure-sensitive adhesives for bonding flexible printing plates

A pressure-sensitive adhesive comprising at least 60 wt % of a polymer blend, where the polymer blend consists of a first polymer component a, a second polymer component b, and optionally one or more further polymer components (c, d, . .

Branched polycarbonate production method

Provided is a method of producing a branched polycarbonate, including: a step (a) of subjecting an alkali aqueous solution of a dihydric phenol, phosgene, and a branching agent to a phosgenation reaction in the presence of an organic solvent to provide a reaction liquid; a step (b) of adding the alkali aqueous solution of the dihydric phenol and a polymerization catalyst to the reaction liquid obtained from the step (a) to provide a reaction liquid containing a polycarbonate oligomer; a step (c) of separating the reaction liquid containing the polycarbonate oligomer obtained in the step (b) into an organic solvent phase containing the polycarbonate oligomer and an aqueous phase; and a step (d) of causing the organic solvent phase containing the polycarbonate oligomer separated in the step (c) and the alkali aqueous solution of the dihydric phenol to react with each other to provide a reaction liquid containing the branched polycarbonate, in which a ratio (x/y) of an addition amount of the polymerization catalyst to be added in the step (b), which is represented by x mol/hr, to a chloroformate group amount of the polycarbonate oligomer in the reaction liquid obtained from the step (b), which is represented by y mol/hr, is 0.0035 or more.. .

Method for producing polycarbonate-polyorganosiloxane copolymer

Provided is a method of producing a polycarbonate-polyorganosiloxane copolymer, including a step (a) of producing a polycarbonate oligomer with an alkaline aqueous solution of a dihydric phenol, phosgene, and an organic solvent, the method further including a step of setting a content of a polycarbonate-polyorganosiloxane copolymer in the organic solvent to be introduced into the step (a) to less than 850 ppm by mass.. .

T1r taste receptors and genes encoding same

Newly identified mammalian taste-cell-specific g protein-coupled receptors, and the genes and cdna encoding said receptors are provided. Specifically, t1r g protein-coupled receptors active in taste signaling, and the genes and cdna encoding the same, are provided, along with methods for isolating such genes and for isolating and expressing such receptors..

Polypeptides for the treatment of angiogenesis or lymphangiogenesis-related diseases

The present invention relates to polypeptides for the treatment of angiogenesis or lymphangiogenesis-related diseases. In particular, the present invention relates to a a polypeptide which comprises or consists of a sequence of at least 5 consecutive amino acids in seq id no: 1 and which comprises at least one amino acid selected from the group consisting of q182, r184, q195, t199..

Mutagenic nucleoside analogs and uses thereof

The present disclosure provides nucleoside analogs of formula (i) or (ii). The nucleoside analogs are expected to show multiple tautomerism and may increase the mutation of an rna and/or dna (be mutagenic) of a virus or cancer cell.

Crystalline forms of a therapeutic compound and uses thereof

Disclosed herein are certain crystalline forms of compound 5, n-(5-((2-(4-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butanamido)imidazo[1,2-0]pyridazin-6-yl)oxy)-2-methylphenyl)-1,3-dimethyl-1/-/-pyrazole-5-carboxamide, as well as pharmaceutical compositions comprising the crystalline forms. The present disclosure further relates to methods for treating or preventing diseases or disorders using the crystalline forms or pharmaceutical compositions thereof in a subject in need thereof, including diseases or disorders associated with abnormal or pathological angiogenesis and/or aberrant signaling of a growth factor signaling pathway (e.g., vascular endothelial growth factor (vegf)), such as proliferative diseases and ocular diseases..

Nonanoic and decanoic acid derivatives and uses thereof

The present disclosure relates to fluorinated compounds of formula i and methods of synthesizing these compounds. The present disclosure also relates to pharmaceutical compositions containing the fluorinated compounds of the disclosure, and methods of treating fibrosis, macular degeneration, diabetic retinopathy (dr), macular edema, diabetic macular edema (dme), and macular edema following retinal vein occlusion (rvo), by administering these compounds and pharmaceutical compositions to subjects in need thereof..

Compounds and their use as bace inhibitors

The present application relates to compounds of formula (i), (ia), or (ib) and their pharmaceutical compositions/preparations. This application further relates to methods of treating or preventing aβ-related pathologies such as down's syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to mci (“mild cognitive impairment”), alzheimer's disease, memory loss, attention deficit symptoms associated with alzheimer's disease, neurodegeneration associated with diseases such as alzheimer's disease or dementia, including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with parkinson's disease..

Isoquinolin-3-yl carboxamides and preparation and use thereof

Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the wnt pathway and/or of one or more of wnt signaling components.

Isoquinolin-3-yl carboxamides and preparation and use thereof

Isoquinoline compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an isoquinoline compound or analogs thereof, in the treatment of disorders characterized by the activation of wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, alzheimer's disease, lung disease, inflammation, auto-immune diseases and osteoarthritis), the modulation of cellular events mediated by wnt pathway signaling, as well as neurological conditions/disorders/diseases linked to overexpression of dyrk1a..

Oxygen transfer agents for the oxidative dehydrogenation of hydrocarbons and systems and processes using the same

A oxygen transfer agent useful for the oxidative dehydrogenation of saturated hydrocarbons includes at least one mixed oxide derived from manganese or compounds thereof, as well as a promoter, such as tungsten and/or phosphorus. The oxygen transfer agent may also include an alkali metal or compounds thereof, boron or compounds thereof, an oxide of an alkaline earth metal, and an oxide containing one or more of one or more of manganese, lithium, boron, and magnesium.

Heterogeneous catalysts for the oxidative dehydrogenation of alkanes or oxidative coupling of methane

Improved methods of oxidative dehydrogenation (odh) of short chain alkanes or ethylbenzene to the corresponding olefins, and improved methods of oxidative coupling of methane (ocm) to ethylene and/or ethane, are disclosed. The disclosed methods use boron- or nitride-containing catalysts, and result in improved selectivity and/or byproduct profiles than methods using conventional odh or ocm catalysts..

Autonomous spray ship and method

An airship and method of providing thrust to an airship are shown. Examples include a number of turbine thrusters coupled to a number of electric motor/generators that supplement thrust from the turbine thrusters.

Submersible having variable lift depending on the navigation mode

An underwater vehicle designed for navigation at the surface or underwater, having a hull, and at least one normal-force generator of force normal to a longitudinal axis of the underwater vehicle, borne by the hull, wherein a forward part of the hull is asymmetric with respect to the longitudinal axis so as to generate lift as the underwater vehicle moves and wherein the lift is in the opposite direction to the resultant of the forces of the normal-force generator or generators is provided.. .

Hybrid drive apparatus

A hybrid drive apparatus is provided to allow setting a variety of driving modes while achieving improvement in transmission efficiency. The hybrid drive apparatus includes an engine, first and second motor generators and a planetary gear mechanism.

Hybrid vehicle and control hybrid vehicle

On simultaneous shifts in which shift control of virtual gear positions overlaps shift control of mechanical gear positions, an electronic control unit is configured to delay output of a shift command on the virtual gear position such that shifts of the virtual gear position and the mechanical gear position are performed in synchronization. Therefore, the virtual gear position and the mechanical gear position are shifted in synchronization, irrespective of a difference between the shift response times, and the feeling of strangeness given to the driver due to shift shock, or the like, is suppressed..

Ink jet printing

Printheads and printers are described herein. In one example, a printhead includes a number of drop generators disposed in a first array and a second array.

Process for forming a sintered iron oxide impregnated carbon nanotube membrane

A process for making an iron oxide impregnated carbon nanotube membrane. In this template-free and binder-free process, iron oxide nanoparticles are homogeneously dispersed onto the surface of carbon nanotubes by wet impregnation.

Carbon nanotube membranes

A process for making an iron oxide impregnated carbon nanotube membrane. In this template-free and binder-free process, iron oxide nanoparticles are homogeneously dispersed onto the surface of carbon nanotubes by wet impregnation.

Exhaust gas treatment device, gas turbine combined cycle power generation system, gas engine power generation system and exhaust gas treatment method

An exhaust gas treatment device capable of treating exhaust gas of a gas turbine or a gas engine includes an exhaust gas treatment catalyst comprising a perovskite composite oxide containing at least ag and dy in an a site and at least mn in a b site.. .

Method and industrial plant for obtaining helium from a helium-containing feed gas

A method of obtaining helium from a helium-containing feed gas. Helium-containing feed gas is fed to a prepurifying unit that uses a pressure swing adsorption process to remove undesirable components from the helium-containing feed gas and obtain a prepurified feed gas.

Solid state random number generator

Both dice and teetotums have been traditionally more portable than traditional spinning wheels as a means of random result generation. This invention aims to make a spinning wheel just as portable as either of the above..

Waveform shapes for treating neurological disorders optimized for energy efficiency

Systems and methods for stimulation of neurological tissue apply a stimulation waveform that is derived by a developed genetic algorithm (ga), which may be coupled to a computational model of extracellular stimulation of a mammalian myelinated axon. The waveform is optimized for energy efficiency..

Compositions for regenerating defective or absent myocardium

Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function..

Process for the production of a hybrid structure consisting of coupled silk fibroin microfibers and nanofibers, hybrid structure thus obtained and its use as implantable medical device

A method is described for the production of hybrid structures formed by the coupling of nanofibrous parts and microfibrous parts made with silk fibroin, possibly hierarchically organized into complex structures comprising more than two of said parts; these hybrid structures are used as implantable biomedical devices with tailored biological, geometrical and structural features, such that they can be adapted to different application requirements in the field of regenerative medicine.. .

Methods of increasing fertility of a male subject with costus speciosus extract

The present disclosure relates to a method of increasing fertility of a male subject, wherein the male subject suffers from reduced fertility resulting from a medication, wherein the medication inhibits sperm cell production by inhibiting spermatogenesis in a testis of the male subject, and wherein the method comprises administering to the male subject an effective amount of an extract of costus speciosus in combination with the medication to prevent, and/or reduce the inhibition of sperm cell production by the medication to increase the fertility of the male subject.. .

Antibacterial and protective formulations and methods for making and using them

Provided are compositions and methods for treating, ameliorating and preventing various infections, disorders and conditions in mammals, including genetically-predisposed and chronic disorders, where a microbial or bacterial flora is at least one causative or symptom-producing factor, where exemplary compositions are products of manufacture, a food, a drink, a nutraceutical, a dietary supplement, a formulation, a pharmaceutical or a pharmaceutical preparation comprising at least one or several of a plurality of isolated, or substantially purified bacteriophages or prophages, or bacteriophage subunits, a milk, a milk product, milk lipid, c milk fat globule (mfg) macromolecule, a milk mucin, a milk glycolipid, a milk free glycan, a milk mucin-like glycoprotein, a milk protein, a milk sugar or lactose, a milk fat or butterfat, a milk vitamin. In alternative embodiment, provided are compositions and methods for treating, preventing or ameliorating an infection, for example, an infection in the gastrointestinal tract, or bowel..

Bacteria engineered to reduce hyperphenylalaninemia

Genetically engineered bacteria, pharmaceutical compositions thereof, and methods of modulating and treating diseases associated with hyperphenylalaninemia are disclosed.. .

Cell-based therapy for the pulmonary system

Cell based therapy comprises administration to the lung by injection into the blood system of viable, mammalian cells effective for alleviating or inhibiting pulmonary disorders. The cells may express a therapeutic transgene or the cells may be therapeutic in their own right by inducing regenerative effects..

Cartilage cells with a high regenerative potential and low immune response for use in cellular therapy

Cell-based therapies for cartilage repair and regeneration selectively using chondrocytes carrying a cd24 surface marker are disclosed. In particular, chondrocytes carrying the cd24 surface marker have a high regenerative potential and low responsiveness to inflammatory cues.

Engineered dendritic cells and uses for the treatment of cancer

This invention provides the field of therapeutics. Most specifically present invention provides methods of generating in vitro engineered dendritic cells conditionally expressing interleukin-12 (il-12) under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals including human..

Method for improving interstitial flow

Provided is a prophylactic and/or therapeutic drug for mild cognitive impairment, which can improve interstitial flow in cerebral blood vessel and the like to achieve sufficient clearance of harmful proteins accumulated in the brain. The prophylactic and/or therapeutic drug includes 6-[4-(1-cyclohexyl-1h-tetrazole-5-yl)butoxy]3,4-dihydrocarbostyril or a salt thereof as an active ingredient.

Compositions and methods for modulating metabolic pathways

Compositions and methods useful for inducing an increase in fatty acid oxidation or mitochondrial biogenesis, reducing weight gain, inducing weight loss, or increasing sirt1, sirt3, or ampk activity are provided herein. Such compositions can contain synergizing amounts of a sirtuin-pathway activators, including but not limited to resveratrol, in combination with beta-hydroxymethylbutyrate (hmb), keto isocaproic acid (kic), leucine, or combinations of hmb, kic and leucine..

Sunscreen compositions containing an ultraviolet radiation-absorbing polymer

Compositions including a discontinuous oil phase homogeneously dispersed in a continuous water phase, the oil phase containing a sunscreen agent that includes a polymer composition containing a linear, ultraviolet radiation absorbing polyether, the linear, ultraviolet radiation absorbing polyether including a chemically bound uv-chromophore; and an oil-in water emulsifier component including an anionic oil-in-water emulsifier in an amount such that the composition includes about 0.5 percent by weight to about 3 percent by weight of the anionic oil-in-water emulsifier.. .

Resilient interpositional arthroplasty device

This disclosure is directed to restoring joints by deploying a resilient interpositional arthroplasty implant. Such implants function to pad cartilage defects, cushion, and replace or restore the articular surface, which may preserve joint integrity, reduce pain and improve function.

Method for augmenting a surgical field with virtual guidance content

One variation of a method for augmenting a surgical field with virtual guidance content includes: accessing a scan representing a tissue of a patient; combining the scan with a generic virtual anatomical model to define a custom virtual anatomical model of the tissue; defining a cut trajectory along an intersection between a virtual model of a surgical implant and the custom virtual anatomical model of the tissue; aligning a virtual cut surface to the cut trajectory to locate the virtual model of the surgical guide relative to the custom virtual anatomical model; accessing an image of a surgical field; detecting the tissue in the image; aligning the custom virtual anatomical model to the tissue detected in the image; defining a target real location for a real surgical guide in the surgical field; and generating a frame depicting the target real location of the surgical guide in the surgical field.. .

Method for augmenting a surgical field with virtual guidance content

One variation of a method for augmenting a surgical field with virtual guidance content includes: accessing a scan representing a tissue of a patient; combining the scan with a generic virtual anatomical model to define a custom virtual anatomical model of the tissue; defining a cut trajectory along an intersection between a virtual model of a surgical implant and the custom virtual anatomical model of the tissue; aligning a virtual cut surface to the cut trajectory to locate the virtual model of the surgical guide relative to the custom virtual anatomical model; accessing an image of a surgical field; detecting the tissue in the image; aligning the custom virtual anatomical model to the tissue detected in the image; defining a target real location for a real surgical guide in the surgical field; and generating a frame depicting the target real location of the surgical guide in the surgical field.. .

System and high frequency leakage reduction through selective harmonic elimination in electrosurgical generators

An electrosurgical generator includes: a power supply configured to output a dc waveform; an inverter coupled to the power supply, the inverter including a plurality of switching elements; and a controller coupled to the inverter and configured to generate a switching angle waveform including a plurality of switching pulses. The controller is further configured to at least one of select or calculate the plurality of switching pulses to activate the plurality of switching elements to generate a radio frequency waveform based on the dc waveform and to minimize harmonics of the radio frequency waveform..

Humanized il-7 rodents

Genetically modified non-human animals comprising a human or humanized interleukin-7 (il-7) gene. Cells, embryos, and non-human animals comprising a human or humanized il-7 gene.

Triple transgenic pigs suitable for xenograft

The application provides methods of improving a rejection related symptom, reducing premature separation and methods of producing a compound of interest with an altered epitope profile are provided. Knockout pigs with a disrupted gene or genes, and porcine organs, tissues, and cells therefrom are provided..

Genetically modified rat derived from rat embryonic stem cell

The present invention provides a rat embryonic stem cell characterized by having the following properties of (a) expressing oct3/4 gene and nanog gene, (b) positive for alkaline phosphatase activity, (c) having an embryoid body forming ability, (d) expressing ssea (stage-specific embryonic antigen)-1 and ssea-4, (e) having the same number of chromosomes as does a normal rat cell, (f) capable of being subcultured and holding the undifferentiated state, (g) having in vitro pluripotency, (h) having a potential to differentiate for cells of three embryonic germ lineages, (i) having teratoma formation ability, and (j) having an ability to produce a chimeric rat, a method of establishing the aforementioned rat embryonic stem cell and the like.. .

Method and generating highly repetitive pulsed plasmas

A pulsed radio frequency inductive plasma source and method are provided. The source may generate plasma at gas pressures from 1 torr to 2000 torr.
Plasmanano Corporation

Interface of an m2m server with the 3gpp core network

An m2m server may be integrated into a 3gpp network. A network node, for example a serving general packet radio service (gprs) support node (sgsn) may include a dedicated interface with a m2m server.
Interdigital Patent Holdings, Inc.

Systems and methods for reusing generic tokens using bluetooth low energy (ble) beacons

Systems and methods for reusing generic tokens using a bluetooth® low energy (ble) beacon. The systems and methods include a user device including a wireless transceiver, a memory for storing a generic token, and one or more processors coupled to the memory and the wireless transceiver.
Paypal, Inc.

Mobile communication in macro-cell assisted small cell networks

A user equipment (ue) device operates to directly determine a target small cell for access or handover with the assistance of a macro cell network. The ue directly generates the connection and selects which small cell to access from among a subset of small cells chosen of a set of candidate small cells.
Intel Ip Corporation

Methods and direct communication key establishment

A ue, a device and a direct communication element. The ue is configured to establish a ue shared key with a bootstrapping server function (bsf) using a generic bootstrapping architecture (gba) procedure, to discover the device through a discovery procedure after establishing the ue shared key, and to derive a direct communication key from at least the ue shared key.
Telefonaktiebolaget Lm Ericsson (publ)





Follow us on Twitter
twitter icon@FreshPatents

###

This listing is a sample listing of patent applications related to Gene for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for Gene with additional patents listed. Browse our RSS directory or Search for other possible listings.


0.7743

file did exist - file did put12828

4 - 1 - 259