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Gene-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Dirty paper coding in wireless networks
Alcatel-lucent Usa Inc.
April 12, 2018 - N°20180103480

The present disclosure generally discloses an interference mitigation capability. The present disclosure discloses use of dirty paper coding in a wireless communication network in order to mitigate interference in the wireless communication network. The wireless communication network may be a heterogeneous wireless communication network, where heterogeneity may be based on wireless access device technology type, wireless access device transmit power, ...
Sleep-state for mobile terminal and service initiation for mobile terminals in sleep-state
Panasonic Intellectual Property Corporation Of America
April 12, 2018 - N°20180103399

The invention relates to the initiation of a service to a mobile terminal capable of communicating via at least a first and second access network. Further, the invention relates to a reduction of power consumption of mobile terminals supporting connectivity to at least two access networks. The invention also relates to mobile communication systems and in particular to mobile communications ...
Service layer resource management for generic interworking and extensibility
Convida Wireless, Llc
April 12, 2018 - N°20180102934

Lightweight, dynamic mechanisms are provided to support service layer interworking and resource extensibility. For example, one mechanism disclosed herein comprises defining a new service layer (sl) resource definition registration procedure that allows for specifying custom attributes of service layer resources to represent third party technology resources. A second mechanism disclosed herein comprises defining a new sl data model mapping registration ...
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Portable power case
Lat Enterprises, Inc., D/b/a Medipak Energy Systems
April 12, 2018 - N°20180102656

Systems, methods, and articles for a portable power case are disclosed. The portable power case is comprised of at least one battery and at least one pcb. The portable power case has at least two access ports, at least two leads, or at least one access port and at least one lead and at least one usb port. The portable ...
Power system reliability
Transocean Sedco Forex Ventures Limited
April 12, 2018 - N°20180102650

A power system may include autonomous breakers coupling generators to a main bus. The autonomous breakers may detect deviation of power parameters of the main bus from a predetermined range and couple generators to the main bus to bring the power parameters within the predetermined range. Autonomous breakers may further couple loads to the main bus and may adjust loads ...
52-gene signature in peripheral blood identifies a genomic profile associated with increased risk of mortality ...
Yale University
April 12, 2018 - N°20180101642

The clinical course of idiopathic pulmonary fibrosis (ipf) is difficult to predict. Described herein is a peripheral blood 52-gene expression signature useful to improve outcome prediction in ipf.
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System to search heterogeneous data structures
Sap Se
April 12, 2018 - N°20180101572

A system includes reception of a first query to search two or more heterogeneous data providers, generation of a first query language excerpt to define a combined key column based on key columns associated with a first data provider of the two or more heterogeneous data providers, for each of two or more columns of the first data provider, generation ...
Secured pseudo-random number generator
International Business Machines Corporation
April 12, 2018 - N°20180101361

The present invention provides a method of generating a sequence of pseudo-random numbers which are difficult to predict. The method includes: (i) generating a plurality of candidate pseudo-random numbers by a respectively corresponding plurality of (differently structured) linear feedback shift registers; (ii) generating a “selector number” from one or more additional linear feedback shift registers; and (...
Secured pseudo-random number generator
International Business Machines Corporation
April 12, 2018 - N°20180101360

The present invention provides a method of generating a sequence of pseudo-random numbers which are difficult to predict. The method includes: (i) generating a plurality of candidate pseudo-random numbers by a respectively corresponding plurality of (differently structured) linear feedback shift registers; (ii) generating a “selector number” from one or more additional linear feedback shift registers; and (...
Performance-balanced heterogeneous raid
International Business Machines Corporation
April 12, 2018 - N°20180101301

A method for balancing performance in a redundant array of independent disks (raid) made up of heterogeneous storage drives is disclosed. In one embodiment, such a method includes implementing a raid on a set of storage drives. The set of storage drives includes a lower-performing storage drive that underperforms other storage drives in the set. In order to balance performance ...
Automatic generation of test sequences
United States Of America As Represented By The Secretary Of The Navy
April 12, 2018 - N°20180100894

Disclosed here is a system which uses simulations of an electronic circuit and a classifier to create an optimized test program set. A user provides a model of the circuit, including descriptions of common faults. Candidate test signals are simulated in the circuit, evaluated using a classifier and a fitness function which optimizes for fault detection and isolation, and evolved ...
Simplified nuclei analysis platform and biomarker matrix that supports genotoxic mode of action determinations
Litron Laboratories, Ltd.
April 12, 2018 - N°20180100851

The present invention relates a simple method for evaluating free eukaryotic cell nuclei for biomarkers of dna damage and/or transcription factor activation, activity, or expression levels and/or epigenetic modifications to chromatin or chromatin-associated factors. The invention also teaches useful strategies for combining nuclear biomarkers into a matrix of endpoints that are capable of elucidating genotoxicants' primary mode of ...
Plasma spectroscopic analysis method and inhibitor of plasma emission derived from non-target
Arkray, Inc.
April 12, 2018 - N°20180100803

A plasma spectroscopic analysis method includes a concentration process of concentrating a target in a sample, in the vicinity of one of a pair of electrodes in the presence of the sample; a plasma generation process of generating plasma in the sample by applying a voltage to the pair of electrodes; and a detection process of detecting emission of the ...
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Grain refinement in iron-based materials
The Curators Of The University Of Missouri
April 12, 2018 - N°20180100208

A process for manufacturing an iron-based alloy comprising forming targeted fine oxide and/or carbide dispersoids in a melt, and sequentially precipitating transition-metal nitrides on the dispersoids for heterogeneous nucleation of equiaxed grains. An iron-based cast alloy having a highly equiaxed fine grain structure.
Tumor and microenvironment gene expression, compositions of matter and methods of use thereof
The General Hospital Corporation
April 12, 2018 - N°20180100201

This invention relates generally to compositions and methods for identifying genes and gene networks that respond to, modulate, control or otherwise influence tumors and tissues, including cells and cell types of the tumors and tissues, and malignant, microenvironmental, or immunologic states of the tumor cells and tissues. The invention also relates to methods of diagnosing, prognosing and/or staging of ...
Method for determining prognosis of breast cancer patient by using gene expression data
Gwangju Institute Of Science And Technology
April 12, 2018 - N°20180100199

A method for determining prognosis of a breast cancer patient according to an embodiment includes: collecting information on cancer tissue in a patient group from patient information determined to have breast cancer, collecting gene expression information of each patient group, sorting genes by performing a test for a group having a high expression level and a group having a low ...
Dna methylation markers for metastatic prostate cancer
The Johns Hopkins University
April 12, 2018 - N°20180100196

The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for assessing prostate cancer. In a specific embodiment, present inventors have developed and applied a new technology and associated computation methods enabling simultaneous genome-scale analysis of genetic (copy number) and epigenetic (total methylation (tm) and allele-specific methylation (asm) alternation, this method, ...
Risk stratification method for a patient having a polymorphism
Helicalhelp Llc
April 12, 2018 - N°20180100195

A risk stratification method for a patient in a disease state and specifically patients presenting a tumor, includes determining if the patient is a homozygote or heterozygote and further determining the allelic expression for the patient, cc, t/c, or c/t. For patients having the cytosine methylated, they have a t/c allelic expression and patients without a methylated ...
Modified microorganism for the optimized production of 2,4-dihydroxybutyrate
Metabolic Explorer
April 12, 2018 - N°20180100169

The present invention relates to a genetically modified microorganism for the production of 2,4-dihydroxybutyrate, by metabolic transformation of xylose via the 1,2,4-butanetriol intermediate. The invention also relates to a method for the production of 2,4-dihydroxybutyrate by culturing said genetically modified microorganism in a fermentation medium and recovering 2,4-dhb from said medium.
Methods for enriching gene-targeted cells
Institute For Cancer Research D/b/a The Research Institute Of Fox Chase Cancer Center
April 12, 2018 - N°20180100167

A gene of interest and the gene encoding hypoxanthine-aminopterin-thymidine (hprt) can be co-targeted for casp9 nuclease-mediated editing or alteration in a cell. Based on whether the hprt gene is altered to encode a non-functional protein, or is not so-altered, the co-targeted cells can be selected and counter-selected. Hprt co-targeting can be used to sequentially disrupt as many genes of interest ...
Modulation of transgene expression in plants
Dow Agrosciences Llc
April 12, 2018 - N°20180100162

This disclosure concerns the use of endogenous plant rnai machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in seed tissues of a dicot plant.
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