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Residual risk analysis system, method and computer program product therefor

Plenoptic otoscope

Date/App# patent app List of recent Gates-related patents
 Pressure navigation on a touch sensitive user interface patent thumbnailPressure navigation on a touch sensitive user interface
A menu and application navigation system utilizing pressure includes a display device including a touch sensitive user interface, and a navigation engine coupled to the display device. The navigation engine is configured to generate a measurement of pressure applied by a user as a function of time at the touch sensitive user interface.
 Residual risk analysis system, method and computer program product therefor patent thumbnailResidual risk analysis system, method and computer program product therefor
Systems, methods and products for determining residual values of asset portfolios are disclosed. In one embodiment, a system includes a server computer coupled to a network and to a data storage device.
 Plenoptic otoscope patent thumbnailPlenoptic otoscope
A plenoptic otoscope enables three-dimensional and/or spectral imaging of the inside of the ear to assist in improved diagnosis of inflammations and infections. The plenoptic otoscope includes a primary imaging system and a plenoptic sensor.
 Novelcrosslinking reagents, macromolecules, therapeutic conjugates, and synthetic methods thereof patent thumbnailNovelcrosslinking reagents, macromolecules, therapeutic conjugates, and synthetic methods thereof
The invention provides novel chemical entities based on sugar alcohols. These new chemical entities are biocompatible and biodegradable.
 Antioxidant small molecules aimed at targeting metal-based oxidative stress in neurogenerative disorders patent thumbnailAntioxidant small molecules aimed at targeting metal-based oxidative stress in neurogenerative disorders
Amine chelates capable of antioxidant capacity and amyloid disaggregation are shown which may be useful in targeting metal-based oxidative stress in neurodegenerative disorders. Pyclen, a backbone commonly investigated for contrast agent imaging, may be repurposed as an anti-oxidant chelator for disaggregating amyloid.
 Antioxidant small molecules aimed at targeting metal-based oxidative stress in neurodegenerative disorders patent thumbnailAntioxidant small molecules aimed at targeting metal-based oxidative stress in neurodegenerative disorders
Amine chelates capable of antioxidant capacity and amyloid disaggregation are shown which may be useful in targeting metal-based oxidative stress in neurodegenerative disorders. Pyclen, a backbone commonly investigated for contrast agent imaging, may be repurposed as an anti-oxidant chelator for disaggregating amyloid.
 Targeting vector-phospholipid conjugates patent thumbnailTargeting vector-phospholipid conjugates
Peptide vectors having high kdr binding affinity and processes for making such vectors are provided. The peptide vectors may be conjugated to phospholipids and included in ultrasound contrast agent compositions.
 Kisspeptide-pentasaccharide conjugates patent thumbnailKisspeptide-pentasaccharide conjugates
The invention relates to kisspeptide-pentasaccharide conjugates having the general formula (i) wherein z1 is tyr or d-tyr; z3 is trp, hyp, phe or lys(r2); z5 is thr, aib or ala; z7 is gly or azagly; z8 is leu; or z7 and z8 together represent; z10 is phe or trp; n is 0 or 1; or r2, when present, represents a pentasaccharide derivative having the formula (ii) wherein r is methyl or so3x; x is a positively charged counterion; with the proviso that when r2 is present, r1 is h or (c1-6) alkylcarbonyl; r3 is h or (c1-3)alkyl; and l represents a pharmacologically inactive linker moiety having 10-50 atoms; or a pharmaceutically acceptable salt thereof; to pharmaceutical compositions comprising the same as well as to the use of said kisspeptide-pentasaccharide conjugates in the treatment of female infertility.. .
 Semiconductor constructions, methods of forming transistor gates, and methods of forming nand cell units patent thumbnailSemiconductor constructions, methods of forming transistor gates, and methods of forming nand cell units
Some embodiments include methods of forming charge storage transistor gates and standard fet gates in which common processing is utilized for fabrication of at least some portions of the different types of gates. Fet and charge storage transistor gate stacks may be formed.
 Cancer treatment comprising therapeutics that bind to phosphatidylserine patent thumbnailCancer treatment comprising therapeutics that bind to phosphatidylserine
Disclosed is the surprising discovery that aminophospholipids, such as phosphatidylserine and phosphatidylethanolamine, are specific, accessible and stable markers of the luminal surface of tumor blood vessels. The present invention thus provides aminophospholipid-targeted diagnostic and therapeutic constructs for use in tumor intervention.
Sheet processing apparatus and image forming system
In order to correct a corrugation caused when a sheet widthwise edge portion elongates more than the vicinity of the center in a sheet feeding direction, a sheet processing apparatus includes: a fixing portion that fixes a toner image onto a sheet by heating, a plurality of pairs of rollers provided along a sheet feeding direction with an interval in the downstream of the fixing portion in the feeding direction to nip and convey a sheet; and a tensioning device that applies a tensile strength of the sheet feeding direction to a sheet in a center area of a width direction perpendicular to the sheet feeding direction.. .
Processing source video for real-time enhancement of a signal of interest
What is disclosed is a system and method for real-time enhancement of an identified time-series signal of interest in a video that has a similar spatial and temporal structure to a given reference signal, as determined by a measure of closeness. A closeness measure is computed for pixels of each image frame of each channel of a multi-channel video to identify a time-series signal of interest.
Temperature sensor and temperature sensing method
Provided is a temperature sensing circuit and a temperature sensing method including a delay unit delaying an input clock signal to generate a feedback clock signal, and including logic gates of which delay times are variable according to temperature, a delay control unit comparing the feedback clock signal with a reference clock signal and controlling each of the logic gates of the delay unit according to the comparison result, and an input signal control unit selecting, as the input clock signal, any one of the feedback clock signal and the reference clock signal to input the input clock signal to the delay unit.. .
Line voltage boost system and method for non-volatile memory devices and memory devices and processor-based system using same
The voltage of a selected word line is increased beyond the voltage to which a respective string driver transistor is capable of driving the word line by capacitively coupling a voltage to the selected word line from adjacent word lines. The voltage is capacitively coupled to the selected word line by increasing the voltages of the adjacent word lines after a programming voltage has been applied to a string driver transistor for the selected word line and after a string driver voltage has been applied to the gates of all of the string driver transistors in an array..
Semiconductor memory device using only single-channel transistor to apply voltage to selected word line
A semiconductor memory device has a memory cell array, a first transistor of a first conductivity type, a second transistor of a second conductivity type and a third transistor of the first conductivity type. A source or drain of the first transistor is connected to each of word lines.
Resistive memory device
A resistive memory device includes memory cell array blocks, a reference cell array block, two first and second sink transistors, and a word line. Each of the memory cell array blocks includes a row line, and the reference cell array block includes a reference row line.
Systems using eye mounted displays
A display device is mounted on and/or inside the eye. The eye mounted display contains multiple sub-displays, each of which projects light to different retinal positions within a portion of the retina corresponding to the sub-display.
Power supply circuit for memory
A voltage pin of a pwm controller is electrically connected to a power source. First and second gate pins of the pwm controller are electrically connected to gates of first and second mosfets, respectively.
Integrated step and grab-handle system for tailgates
A deployable step and handle system for a tailgate. The handle is used to secure the deployable step in the stowed position that eliminates the need for a separate release system.
Metal-insulator-metal capacitor formation techniques
Techniques and structure are disclosed for providing a mim capacitor having a generally corrugated profile. The corrugated topography is provisioned using sacrificial, self-organizing materials that effectively create a pattern in response to treatment (heat or other suitable stimulus), which is transferred to a dielectric material in which the mim capacitor is formed.
Solid-state photodetector pixel and photodetecting method
A pixel is formed in a semiconductor substrate (s) with a plane surface for use in a photodetector. It comprises an active region for converting incident light (in) into charge carriers, photogates (pgl, pgm, pgr) for generating a lateral electric potential (Φ(x)) across the active region, and an integration gate (ig) for storing charge carriers generated in the active region and a dump site (ddiff).
N/p boundary effect reduction for metal gate transistors
The present disclosure provides a method of fabricating a semiconductor device. The method includes forming a plurality of dummy gates over a substrate.
Semiconductor devices including gates and dummy gates of different materials
Semiconductor devices are provided. The semiconductor devices may include an active pattern and a insulation layer.
Wire-last integration method and structure for iii-v nanowire devices
In one aspect, a method of fabricating a nanowire fet device includes the following steps. A layer of iii-v semiconductor material is formed on an soi layer of an soi wafer.
Electrical test structure for devices employing high-k dielectrics or metal gates
A test structure includes an active region formed in a semiconducting substrate, a first line formed above and extending over an upper surface of the active region, and a first isolation region formed in the semiconducting substrate, wherein the active region surrounds the first isolation region. The test structure further includes a first extension formed above the active region and on and in contact with an upper surface of the first isolation region, wherein the first extension extends laterally over the upper surface of the active region from a first side of the first line.
Wire-last integration method and structure for iii-v nanowire devices
In one aspect, a method of fabricating a nanowire fet device includes the following steps. A layer of iii-v semiconductor material is formed on an soi layer of an soi wafer.
Match server for a financial exchange having fault tolerant operation
Fault tolerant operation is disclosed for a primary match server of a financial exchange using an active copy-cat instance, a.k.a. Backup match server, that mirrors operations in the primary match server, but only after those operations have successfully completed in the primary match server.
Systems and methods for personalizing aggregated news content
A system customizes a news document associated with a user of a news aggregation service. The system includes multiple news source servers that store news content and a remote news aggregation server.
Hand held integrated pedicle screw placement device
A device for applying a medical element has a housing defining a longitudinal axis with a channel disposed therethrough. The housing has a proximal and a distal opening.
Bisaminoethanethiol-targeting ligand conjugates and compositions
The invention provides, in a general sense, a new labeling strategy employing 99mtc chelated with ethylenedicysteine (ec). Ec is conjugated with a variety of ligands and chelated to 99mtc for use as an imaging agent for tissue-specific diseases.
Pegylated lipids and their use for drug delivery
The invention provides poly(ethylene glycol)-lipid conjugates for use in drug delivery.. .
Oligomer-opioid agonist conjugates
The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer..
Cement hydrate products for sprayed concrete
Process for the preparation of a sprayable inorganic binder composition containing as main components water, aggregates, inorganic binder, set accelerator, characterized in, that a cement hydrate products containing component is added before and/or at the spray nozzle.. .
Bio-orthogonal drug activation
The invention relates to a prodrug activation method, for therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention also relates to a prodrug kit comprising at least one prodrug and at least one activator, wherein the prodrug comprises a drug and a first bio-orthogonal reactive group (the trigger), and wherein the activator comprises a second bio-orthogonal reactive group.
Interferon alpha antibodies and their uses
The present invention provides isolated anti-interferon alpha monoclonal antibodies, particularly human monoclonal antibodies, that inhibit the biological activity of multiple interferon (ifn) alpha subtypes but do not substantially inhibit the biological activity of ifn alpha 21 or the biological activity of either ifn beta or ifn omega. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided.
Apparatus and method for determining temperature
An apparatus and method for determining temperature is disclosed. An ultrasonic signal is generated that propagates through a buffer and a portion of the signal is reflected at an interface.
Identification of data flows based on actions of quality of service policies
In one embodiment, a method comprises determining a quality of service (qos) policier action for data packets belonging to a first flow of data packets received at an ingress interface of a network switching device, the qos policier action based on one of multiple prescribed qos classifications by a qos policier that aggregates distinct flows of data packets into a single aggregated flow according to prescribed qos thresholds; and assigning to the first flow of data packets a unique identifier that associates the qos policier action to identification of the first flow of data packets, enabling identification of the distinct flows of data packets within each of the prescribed qos classifications.. .
Light guiding system, edge-type backlihgt module, and liquiddisplay device
A light guiding system, an edge-type backlight module and a liquid crystal display are disclosed. The light guiding system includes an ambient light collection system facing toward ambient light for absorbing the ambient light, a plurality of light guiding devices, and a fluorescent film arranged between the light emitting ends and the light incident surface.
Walk-through security gate, in particular for use at airports
The invention relates to a walk-through security gate (1), in particular for the use at airports for demarcation between a secured zone and an unsecured zone, wherein the gate can be opened in accordance with the checking of access data such as a flight ticket and a blocking element (6) that blocks the gate is pivoted from a blocked position into a walk-through position in the context. Corresponding fully automatic solutions are part of the prior art in the context.
Capacitor charging circuit with low sub-threshold transistor leakage current
A capacitor charging circuit has input, output and control nodes, first and second series connected primary fets, and first and second leakage current reduction fets. All of the fets have their gates coupled to the control node.
Trench silicide and gate open with local interconnect with replacement gate process
A semiconductor device fabrication process includes forming insulating mandrels over replacement metal gates on a semiconductor substrate with first gates having sources and drains and at least one second gate being isolated from the first gates. Mandrel spacers are formed around each insulating mandrel.
Bidirectional semiconductor device for protection against electrostatic discharges
An integrated circuit is produced on a bulk semiconductor substrate in a given cmos technology and includes a semiconductor device for protection against electrostatic discharges. The semiconductor device has a doublet of floating-gate thyristors coupled in parallel and head-to-tail.
Method for measuring amount of particulate matter accumulated in an exhaust gas purification filter
A measurement method capable of accurately evaluating the trapped amount of particulate matter (pm) accumulated in a diesel particulate filter (dpf) is provided. The method for measuring the amount of accumulated particulate matter comprises propagating ultrasonic waves generated by a transmitter 3 provided directly to the dpf or outside a container and insulation material 6 having a property that propagates ultrasonic waves, measuring the amount of pm accumulated in the dpf 2 using a receiver 4, the dpf being composed of porous ceramic and disposed at an intermediate point in the exhaust pipe 1 of a diesel engine, and determining the amount of accumulated pm on the basis of the results..
Process for upgrading low rank carbonaceous material
A process for upgrading brown coal having a first water content including subjecting the brown coal to a conditioning step which includes heating the brown coal to a first temperature to produce a conditioned brown coal having a second water content which is lower than the first water content; attritioning the conditioned brown coal to enable water to be released from the microstructure of the brown coal and thereby producing an admixture of the brown coal and released water; forming aggregates of the admixture; drying the aggregates to produce upgraded brown coal having a third water content which is lower than the second water content.. .
Applications of glass microparticles and nanoparticles manufactured from recycled glasses
Glass microparticles and/or glass nanoparticles have been developed for use as: reflective paints; abrasive papers/wheels; flame retardant paints; thermal insulation for aggregates, self-cleaning building materials, absorbent of oils, diesel, gasoline, brake fluids, transmission fluids, ethanol, methanol, and acetone; cosmetics (lipstick, foundation, etc.), medicated dental implant, and targeted drug delivery systems.. .
Customer experience monitor
A network monitoring system is provided that includes a plurality of tiers being arranged in a network having a plurality of hardware and software resources for executing a selective number of applications. The tiers include disparate technology stack formats.
System and method for compliance risk mitigation
An approach for handling a complain issue due to absence is provided. The approach includes a computer system identifying a compliance issue.
Antibody drug conjugates (adc) that bind to 161p2f10b proteins
Antibody drug conjugates (adc's) that bind to 161p2f10b protein are described herein. 161p2f10b exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in table i.
Seamless transition of data services in a single-sim multi-active cellular device
Systems, apparatuses and methods are described for seamless transition of data services in a single-sim multi-active (ssma) cellular device operating in a mixed technology cellular network. An ssma device provides multiple virtual terminals capable of simultaneously maintaining multiple active services on different technology networks.
Reducing gate height variance during semiconductor device formation
In general, aspects of the present invention relate to approaches for forming a semiconductor device such as a fet with reduced gate stack height variance. Specifically, when a gate stack height variance is detected/identified between a set of gate stacks, a hard mask layer and sets of spacers are removed from the uneven gate stacks leaving behind (among other things) a set of dummy gates.
Pyrenyloxysulfonic acid fluorescent agents
The invention provides a novel class of reactive fluorescent agents that are based on a pyrene sulfonic acid nucleus. The agents are readily incorporated into conjugates with other species by reacting the reactive group with a group of complementary reactivity on the other species of the conjugate.
Glucose-peg conjugates for reducing glucose transport into a cell
There is provided a glucose-peg conjugate comprising a peg moiety conjugated to a linear glucose moiety at the c1 position of the glucose moiety. The glucose-peg conjugate may be used to reduce glucose transport into a cell and may be used to treat a proliferative disorder..
Fuel cell systems and related methods
A fuel cell system having a fuel cell generator and a fuel cartridge that is removably attachable to the fuel cell generator is disclosed. The fuel cartridge includes a housing having a port, a normally closed valve disposed in the housing that gates fuel emerging from the port, the valve having a poppet that modulates opening of the valve, the poppet having a control surface.
Polyelectrolyte multilayers having salt-controlled internal structures
A method, and an article made therefrom, of: contacting a substrate with a first solution of first polyelectrolyte chains to form a layer of the first polyelectrolyte on the substrate; and contacting the layer of the first polyelectrolyte with a second solution of second polyelectrolyte chains to form a layer of the second polyelectrolyte. The first polyelectrolyte has a polyanion or polycation chain.
Polymer-agent conjugates, particles, compositions, and related methods of use
Described herein are polymer-agent conjugates and particles, which can be used, for example, in the treatment of cancer. Also described herein are mixtures, compositions and dosage forms containing the particles, methods of using the particles (e.g., to treat a disorder), kits including the polymer-agent conjugates and particles, methods of making the polymer-agent conjugates and particles, methods of storing the particles and methods of analyzing the particles..
Immunomodulatory agent-polymeric compounds
This invention relates to compositions, and related compounds and methods, of conjugates of immunomodulatory agents and polymers or unit(s) thereof. The conjugates may be contained within synthetic nanocarriers, and the immunomodulatory agents may be released from the synthetic nanocarriers in a ph sensitive manner..
Enediyne compounds, conjugates thereof, and uses and methods therefor
Enediyne compounds having a structure according to formula (i), where r0, r2, r3, r4, r5, r6, and r7 are defined herein, can be used in chemotherapeutic drugs, especially in conjugates, for the treatment of diseases such as cancer.. .
Hydrophilic self-immolative linkers and conjugates thereof
The present disclosure provides compounds with a hydrophilic self-immolative linker, which is cleavable under appropriate conditions and incorporates a hydrophilic group to provide better solubility of the compound. The compounds of the present disclosure comprise a drug moiety, a targeting moiety capable of targeting a selected cell population, and a linker which contains an acyl unit, an optional spacer unit for providing distance between the drug moiety and the targeting moiety, a peptide linker which can be cleavable under appropriate conditions, a hydrophilic self-immolative linker, and an optional second self-immolative spacer or cyclization self-elimination linker..
Extracellular targeted drug conjugates
Extracellular-targeted drug conjugates (edc) in which a targeting moiety targeting a protein associated with the na,k-atpase is linked to a drug that interacts with the na,k-atpase through a linker a stable linker are useful in the treatment of disease and as tools for the evaluation of biological systems.. .
Oligosaccharides and oligosaccharide-protein conjugates derived from clostridium difficle polysaccaride ps-i, methods of synthesis and uses thereof, in particular as vaccines and diagnostic tools
The invention relates to a synthetic oligosaccharide representing part of the repeating unit of the clostridium difficile glycopolymer ps-i and having the sequence of the pentasaccharide a-l-rhap-(1→3)-β-d-glcp-(1→4)-[a-l-rhap-(1→3]-a-d-glcp-(1→2)-a-d-glcp or a synthetic fragment or derivative thereof. Preferably, the claimed synthetic oligosaccharide bears at least one linker l for conjugation to a carrier protein or for immobilization on a surface.
Antibodies binding to phosphorylcholine (pc) and/or pc conjugates
The present disclosure relates to an antibody or antibody fragment capable of binding to phosphorylcholine and/or a phosphorylcholine conjugate, wherein the antibody or antibody fragment comprises a variable heavy chain (vh) domain and/or a variable light chain (vl) domain, and wherein (a) the vh domain comprises complementarity determining regions (cdrs) selected from the group consisting of: a cdr1 sequence having identity to the sequence of seq id no: 7; a cdr2 sequence having identity to the sequence of seq id no: 8; and a cdr3 sequence having identity to the sequence of seq id no: 9 or 10; and/or (b) the vl domain comprises cdrs selected from the group consisting of: a cdr4 sequence having identity to the sequence of seq id no: 11; a cdr5 sequence having identity to the sequence of seq id no: 12; a cdr6 sequence having identity to the sequence of seq id no: 13.. .
Drug fusions and conjugates
The present invention relates to drug fusions that have improved serum half lives. These fusions and conjugates comprise polypeptides, immunoglobulin (antibody) single variable domains and glp and/or exendin molecules.
Polymalic acid-based nanobiopolymer compositions
Nanobiopolymeric conjugates based on biodegradable, non-toxic and non-immunogenic poly (β-l-malic acid) pmla covalently linked to molecular modules that include morpholino antisense oligonucleotides (aona), an sirna or an antibody specific for an oncogenic protein in a cancer cell, and an antibody specific for a transferrin receptor protein, are provided. Methods for treating a cancer in subject with nanobiopolymeric conjugates are described..
Targeted delivery and prodrug designs for platinum-acridine anti-cancer compounds and methods thereof
Acridine containing cisplatin compounds have been disclosed that show greater efficacy against cancer than other cisplatin compounds. Methods of delivery of those more effective cisplatin compounds to the nucleus in cancer cells is disclosed using one or more amino acids, one or more sugars, one or more polymeric ethers, c1-6alkylene-phenyl-nh—c(o)—r15, folic acid, αvβ3 integrin rgd binding peptide, tamoxifen, endoxifen, epidermal growth factor receptor, antibody conjugates, kinase inhibitors, diazoles, triazoles, oxazoles, erlotinib, and/or mixtures thereof; wherein r15 is a peptide..
Method to estimate interfractional and intrafractional organ motion for adaptive external beam radiotherapy
A therapy system (10) includes one or more processors (98, 100). The processors (98, 100) are programmed to receive one or more of: (1) dosimetric data from dosimeters (26, 28, 202, 204, 206, 208, 210, 212) implanted within a patient and/or positioned on a vest (200); and (2) motion data from surrogates (18, 20, 22, 24) implanted within the patient.
Universal asymmetry compensation for packet timing protocols
The notion of a “ptp aware” path is one current proposed approach to reduce asymmetry effects. In a fully ptp aware path there is the notion of on-path support mechanisms such as boundary clocks and transparent clocks at every switching or routing node.
Dynamic adaptive aggregation schemes for enhancing performance of communication systems
A method, an apparatus, and a computer program product for communication are provided. The apparatus aggregates data sets as a function of an estimated characteristic of a next data set to arrive, and adaptively adjust the estimated characteristic based on a statistical measure of the estimated characteristic derived from a plurality of previously arrived data sets.
Nonvolatile memory with split substrate select gates and heirarchical bitline configuration
Generally, the present disclosure provides a non-volatile memory device having a hierarchical bitline structure for preventing erase voltages applied to one group of memory cells of the memory array from leaking to other groups in which erasure is not required. Local bitlines are coupled to the memory cells of each group of memory cells.
Reduced diffusion in metal electrode for two-terminal memory
Providing for two-terminal memory that mitigates diffusion of external material therein is described herein. In some embodiments, a two-terminal memory cell can comprise an electrode layer.
Optical element and optical mechanism
An optical element includes a waveguide, a polarizing beam splitter film, and a deflector. The waveguide propagates light incident at a predetermined angle while reflecting the light between first and second planes.
Morphable identity, networkable photonic quantum logic gate system & method
Systems and methods of performing logical operations with photonic quantum logic gates. The logic gates utilize photon states, usually orthogonal linearly polarized states, to selectively enact self-interference operations whose outputs can be altered by inducing phase shifts in one or more portions of the section of the logic gate where the photon states undergo self-interference.

Popular terms: [SEARCH]

Gates topics: Transistors, Ophthalmic, Optical Component, Nanoparticle, Electrical Signal, Replacement Gate, Finite State Machine, State Machine, Coordinates, Culture Media, Antibodies, Supplements, Nucleotide, Ganglioside, Fluorescent Probe

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