Gastrointestinal

Gastrointestinal-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).

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NEW Prodrugs of a jak inhibitor compound for treatment of gastrointestinal inflammatory disease
May 25, 2017 - N°20170145044

The invention provides compounds which are prodrugs of a jak inhibitor agent for the targeted delivery of the jak inhibitor to the gastrointestinal tract of a mammal. The invention also provides pharmaceutical compositions comprising the compounds, methods of using the compounds to treat gastrointestinal inflammatory diseases, and processes and intermediates useful for preparing the compounds.
NEW Marmelin analogs and methods of use in cancer treatment
May 25, 2017 - N°20170144965

A pharmaceutical composition can include: a marmelin analog compound, and a pharmaceutically acceptable carrier having the compound. The compound can be present in a therapeutically effective amount to treat or inhibit a disease state. The disease state can be cancer. The cancer can be selected from brain cancers, head and neck cancers, thyroid cancers, gastrointestinal cancers, esophageal cancers, stomach cancers, ...
NEW Compositions and methods for affecting movement of contaminants, bodily fluids or other entities, and/or ...
May 25, 2017 - N°20170143788

Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the ...
Gastrointestinal Patent Pack
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Gastrointestinal Patent Applications
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Pluripotent autologous stem cells from oral mucosa and methods of use
Ramot At Tel-aviv University Ltd.
May 18, 2017 - N°20170137778

The present invention provides a new readily accessible source of adult somatic stem cells from the gastrointestinal tract in general and oral mucosa in particular, methods for isolating pluripotent stem cells from oral mucosa, cells derived therefrom and uses thereof.
Therapy for gist
Imclone Llc
May 18, 2017 - N°20170137523

The invention provides for the human antibodies that bind to human platelet-derived growth factor receptor alpha (pdgfr alpha), preferably olaratumab, for the treatment of gastrointestinal stromal tumors with pdgfr alpha mutations including d842v.
Gastrointestinal capsule
Vibrant Ltd.
May 18, 2017 - N°20170135897

An ingestible gastrointestinal capsule (gic) for mechanically stimulating a segment of the gastrointestinal (gi) wall by alternately and repeatedly pressurizing, and/or vibrating it is provided. The gic is programmed to being activated following a predefined time delay. The activated gic agitates, shakes, rattles, jolts, vibrates and/or moves in a reciprocal expanding and contracting motion thereby mechanically stimulating the ...
Gastrointestinal Patent Pack
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Gastrointestinal Patent Applications
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inventor
  • 314+ full patent PDF documents of Gastrointestinal-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Method for treating mucositis
Enzychem Lifesciences Corporation
May 11, 2017 - N°20170128404

The invention provides a pharmaceutical composition for preventing or treating mucositis, for example oral mucositis (e. G., oral ulceration) and gastrointestinal mucositis, comprising a monoacetyldiacylglycerol compound, especially plag, and a method of preventing or treating mucositis using the same.
Duodenal gastrointestinal devices and delivery mechanisms
Endosphere, Inc.
May 11, 2017 - N°20170128247

A system for delivering an endolumenal device through an endoscope includes a delivery tool and an adaptor. The delivery tool has an elongate tube configured to hold a portion of the endolumenal device therein and a first connecting feature on a distal end of the elongate tube. The adaptor is configured to attach to a handle of the endoscope. The ...
Methods and systems for acoustic data transmission
Endosphere, Inc.
May 04, 2017 - N°20170126331

A method of communicating with an ingestible capsule includes detecting the location of the ingestible capsule, focusing a multi-sensor acoustic array on the ingestible capsule, and communicating an acoustic information exchange with the ingestible capsule via the multi-sensor acoustic array. The ingestible capsule includes a sensor that receives a stimulus inside the gastrointestinal tract of an animal, a bidirectional acoustic ...
Humanized anti-ige antibodies that crosslink cd23 on b lymphocytes but do not sensitize mast cells
Academia Sinica
May 04, 2017 - N°20170121425

A novel humanized anti-ige antibody is disclosed. The antibody is capable of binding to free ige, membrane-bound ige on b lymphocytes, ige bound by cd23, but not to ige bound by high-affinity ige. Fc receptor on mast cells. The present invention relates to the treatment of ige-mediated diseases, including allergic asthma, allergic rhinitis, atopic dermatitis, food allergy, chronic spontaneous (idiopathic) ...
Dendrimer compositions and use in treatment of necrotizing enterocolitis and other gastrointestinal disorders
The Johns Hopkins University
May 04, 2017 - N°20170119897

A dendrimer formulation, such as a pamam dendrimer or a multiarm peg polymeric formulation has been developed for oral administration to the gastrointestinal tract for treatment of inflammatory diseases associated with infection or cancer. In the preferred embodiment, the dendrimers are in the form of dendrimer nanoparticles comprising poly(amidoamine) (pamam) hydroxyl-terminated dendrimers covalently linked to at least one therapeutic, ...
Method and kit for bowel preparation
Msm Innovations, Inc.
May 04, 2017 - N°20170119846

The present invention provides methods and taste-modifying kits for facilitating cleansing of the gastrointestinal tract of a patient prior to a diagnostic, surgical or therapeutic procedure. The methods and taste-modifying kits can improve patient compliance, and thus, efficacy of the preparation. Specifically, the present methods make the gastrointestinal tract preparation composition palatable for the patient to consume. For example, for ...
Tamper resistant oral opioid agonist formulations
Purdue Pharma L.p.
May 04, 2017 - N°20170119685

Oral dosage forms containing an opioid antagonist in a sequestered form are described. The opioid antagonist is sequestered such that it is not released or substantially not released in the gastrointestinal tract from the dosage form which is administered orally intact. However, when the dosage form is chewed, crushed, heated or dissolved in a solvent, and then administered orally, intranasally, ...
Gastrointestinal Patent Pack
Download 314+ patent application PDFs
Gastrointestinal Patent Applications
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For professional research & prior art discovery
inventor
  • 314+ full patent PDF documents of Gastrointestinal-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Hypotonic microbicidal formulations and methods of use
The Johns Hopkins University
May 04, 2017 - N°20170119662

Hypotonic microbicidal compositions including an antimicrobial, such as an antiviral compound, and a pharmaceutically acceptable carrier in a solution formulation having hypotonic osmolarity have been developed for administration rectally to the gastrointestinal mucosa. In a preferred embodiment for use in preventing or decreasing hiv infection, the microbiocidal is tenofovir, or a prodrug or derivative thereof. The formulations may include additional ...
Intestinal barrier sleeve with expandable anchor section
The Johns Hopkins University
May 04, 2017 - N°20170119567

An intestinal barrier sleeve and corresponding treatments using the sleeve are provided herein. The sleeve generally includes an expanding section coupled to a tubular section at an interface there between. The expanding section is expandable from at least a first collapsed position to at least one expanded position, where the expanding section has a conical shape that when expanded retains ...
Method for selection of agents influencing intestinal motility disorders and pain
The Johns Hopkins University
April 27, 2017 - N°20170114422

B) a step of ex vivo nerve bundle recording carried out on a gastrointestinal segment to analyse the effect of said agent on mesenteric afferent nerve firing. Bacterial strains selected by the methods of the invention and the use of said bacterial strains in the treatment of intestinal motility disorders are also provided.
Magnetic devices and related methods for gastrointestinal restriction
Lifespan Corporation
April 27, 2017 - N°20170112650

A system for restricting a stomach of a patient may include a plurality of discrete magnetic devices. Each magnetic device may include a magnet and be configured to be secured to tissue. A first portion of the plurality of magnetic devices may be configured to be transorally inserted into the patient and secured to a first wall of the stomach, ...
System and method for facilitating assessment of the bowel course and facilitation of transition point ...
Lifespan Corporation
April 20, 2017 - N°20170109922

Novel application of pre-existing flood-fill and thresholding algorithms to radiologic images for the purposes of facilitating and accelerating the task of visual radiologic evaluation of the gastrointestinal tract is presented. This invention facilitates evaluation, in a manner that is useful in the contexts of finding a bowel transition point in cases of suspected bowel obstruction, and for facilitating determination of ...
Apparatus and method for testing medicaments
Ucl Business Plc
April 20, 2017 - N°20170108519

Apparatus for testing the solubility of a medical dosage form includes a chamber (12) for holding a solvent medium (18), in the preferred embodiment a bicarbonate based buffer system. The apparatus also includes a ph probe (66) which is connectable to a supply of carbon dioxide (32, 34), as well as to a supply of helium (40), the supplies being controlled by a control unit (50). The ...
Method for determination of a protein
Bühlmann Laboratories Ag
April 20, 2017 - N°20170108507

The present invention concerns a method for determining the concentration of a protein in a gastrointestinal (gi) tract sample taken from a human or an animal. The present invention is characterized by the feature that a dilution of the sample in the buffered aqueous extraction medium in a range of 1:100 to 1:10,000 is obtained. The present invention leads to a significant ...
Methods of treating incontinence and other sphincter deficiency disorders
Wake Forest University Health Sciences
April 20, 2017 - N°20170106050

A method of treating a sphincter deficiency disorder (e. G., incontinence; gastrointestinal disorders) is carried out by administering stromal cell-derived factor 1 (sdf-1) to a sphincter or sphincter complex, such as a urethral or gastrointestinal sphincter (e. G., a rectal sphincter) of the subject in a treatment-effective amount.