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Gastrointestinal Tract

Gastrointestinal Tract-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Methods and compositions for detecting gastrointestinal and other cancers
Case Western Reserve University
July 20, 2017 - N°20170204470

This application describes methods and compositions for detecting and treating vimentin-associated neoplasia. Differential methylation of the vimentin nucleotide sequences has been observed in vimentin-associated neoplasia such as neoplasia of the upper or lower gastrointestinal tract, pancreas, and/or bladder.
Body worn antenna
Check-cap Ltd.
July 13, 2017 - N°20170196480

A wearable antenna for communicating between an external transceiver and a capsule inside the gastrointestinal tract of a user, including a printed circuit board for forming a conducting pattern on a first face and on a second face of the printed circuit board; a first conducting pattern on the first face of the printed circuit board, including: a) an almost ...
Dialkyl-phosphinoyl-alkane (dapa) compounds and compositions for treatment of lower gastrointestinal tract disorders
Check-cap Ltd.
July 06, 2017 - N°20170189428

Heat abstraction from the body's surfaces causes sensations of cold from the skin, orbit, nose, mouth, throat, upper esophagus, airways, and anogenital surfaces. The detection of heat abstraction at these sites is via trpm8, a neuronal protein linked to nerve membranes. Chemical agents that act on trpm8 can also produce sensations of cold, but the surface of the lower gastrointestinal ...
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Method for bowel preparation
Msm Innovations, Inc.
June 29, 2017 - N°20170182169

The present invention provides methods for facilitating cleansing of the gastrointestinal tract of a patient prior to a diagnostic, surgical or therapeutic procedure. The methods can improve patient compliance, and thus, efficacy of the preparation. Specifically, the present methods make the gastrointestinal tract preparation composition palatable for the patient to consume. For example, for a patient preparing to undergo colonoscopy, ...
4-oxo-1, 4-dihydroquinoline-3-carboxamide as selective ligand for cannabinoid receptor 2 for diagnosis and therapy
Universitaet Zuerich
June 22, 2017 - N°20170174632

The present invention is directed to new compounds selectively binding the cannabinoid 2 receptor. In addition, the invention relates to the use of said compounds for determining cannabinoid receptor 2 (cb2)-selective receptor localization and density, preferably in the central nervous system (cns), the peripheral nervous system (pns), heart, liver, gastrointestinal tract, spleen, pancreas, kidney, testis, ovary and/or the prostate. Moreover, ...
Process to enhance the bioactivity of ashwagandha extracts
Universitaet Zuerich
June 22, 2017 - N°20170173100

The invention relates to an extract of ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The ...
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Methods and apparatus for anchoring within the gastrointestinal tract
Gi Dynamics, Inc.
June 22, 2017 - N°20170172779

The present invention relates to an anchor configured for minimally-invasive implantation and sized to remain securely positioned within at least a portion of the gastrointestinal tract of an animal. The anchor includes a radial spring formed from an elongated resilient member shaped into an annular wave pattern about a central axis. The anchor defines a central lumen and provides an ...
Endoscopic mucosal lift kit
Gi Dynamics, Inc.
June 15, 2017 - N°20170165379

Method and product; for use in the human digestive tract for endoscopic submucosal injection, as an aid in identifying the extent and borders of flat mucosal polyps (neoplasia) and creating a dynamic gastrointestinal tract mucosa lift of the surrounding mucosa for a safe and through snare polypectomy.
Cd8+ regulatory t-cells for use in the treatment of inflammatory disorders of the human gastrointestinal ...
Genovie Ab
June 15, 2017 - N°20170165298

The present invention relates to composition comprising an isolated cd8+ treg cell population, wherein the treg cells have signatures for i) identifying that the t-cells are cd8+ regulatory tcells, ii) identifying that the treg cells are tissue type tropic, i. E they can migrate to the diseased tissue, iii) optionally identifying that the treg cells are tropic with respect to ...
Crosslinked cation exchange polymers, compositions and use in treating hyperkalemia
Relypsa, Inc.
June 15, 2017 - N°20170165292

The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or ...
Ph-responsive mucoadhesive polymeric encapsulated microorganisms
Massachusetts Institute Of Technology
June 15, 2017 - N°20170165201

Methods of encapsulating microorganisms, or components thereof, for targeted enteric delivery to an animal host have been developed. In particular, the encapsulation provides a prolonged survival, extended retention and a ph-sensitive release of the encapsulated microorganisms or antigenic components thereof at targeted sites within the gastrointestinal tract. The formulations are useful for diagnostic, therapeutic and prophylactic purposes and can alter ...
Endoscopic mucosal lift kit
Massachusetts Institute Of Technology
June 15, 2017 - N°20170164970

Method and product; for use in the human digestive tract for endoscopic submucosal injection, as an aid in identifying the extent and borders of flat mucosal polyps (neoplasia) and creating a dynamic gastrointestinal tract mucosa lift of the surrounding mucosa for a safe and through snare polypectomy.
Compositions comprising cinnamaldehyde and zinc and methods of using such compositions
Nestec S.a.
June 15, 2017 - N°20170164648

Compositions comprise an amount of cinnamaldehyde that is orally tolerable, thus avoiding an unpleasant mouth feeling, and also tolerable in the gastrointestinal tract. The amount of cinnamaldehyde is supplemented by zinc, and the combination is effective to increase at least one of energy expenditure, sympathetic nervous system activity, or fat oxidation, relative to a composition lacking cinnamaldehyde and zinc but ...
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Amide dendrimer compositions
Genzyme Corporation
June 01, 2017 - N°20170152347

Amide compounds, amide polymers, compositions including amide compounds and amide polymers may be used to bind target ions, such as phosphorous-containing compounds in the gastrointestinal tract of animals. In some cases, amide compounds and amide polymers may include a core derived from an amide polyol and an organic polyacid or ester.
Prodrugs of a jak inhibitor compound for treatment of gastrointestinal inflammatory disease
Genzyme Corporation
May 25, 2017 - N°20170145044

The invention provides compounds which are prodrugs of a jak inhibitor agent for the targeted delivery of the jak inhibitor to the gastrointestinal tract of a mammal. The invention also provides pharmaceutical compositions comprising the compounds, methods of using the compounds to treat gastrointestinal inflammatory diseases, and processes and intermediates useful for preparing the compounds.
Compositions and methods for affecting movement of contaminants, bodily fluids or other entities, and/or ...
Genzyme Corporation
May 25, 2017 - N°20170143788

Compositions which self-assemble under physiological conditions are formulated for application to wounds. The formulations include a pharmaceutically acceptable carrier or are provided as part of a medical device or coating. The formulations may also include other therapeutic, prophylactic or diagnostic agents. The formulation can be administered as appropriate for treatment of one or more disorders or conditions. For example, the ...
Pluripotent autologous stem cells from oral mucosa and methods of use
Ramot At Tel-aviv University Ltd.
May 18, 2017 - N°20170137778

The present invention provides a new readily accessible source of adult somatic stem cells from the gastrointestinal tract in general and oral mucosa in particular, methods for isolating pluripotent stem cells from oral mucosa, cells derived therefrom and uses thereof.
Medical instrument
Sosaikouseikai Clinical Foundation Matsunami Research Park
May 18, 2017 - N°20170135835

A medical device according to the present invention is to be arranged in a lumen of a gastrointestinal tract. The medical device includes: at least one cylindrical part which is opened at least one end thereof; and at least one attachment part which is arranged on at least one portion of the cylindrical part and is configured such that the ...
Methods and systems for acoustic data transmission
Sosaikouseikai Clinical Foundation Matsunami Research Park
May 04, 2017 - N°20170126331

A method of communicating with an ingestible capsule includes detecting the location of the ingestible capsule, focusing a multi-sensor acoustic array on the ingestible capsule, and communicating an acoustic information exchange with the ingestible capsule via the multi-sensor acoustic array. The ingestible capsule includes a sensor that receives a stimulus inside the gastrointestinal tract of an animal, a bidirectional acoustic ...
Dendrimer compositions and use in treatment of necrotizing enterocolitis and other gastrointestinal disorders
The Johns Hopkins University
May 04, 2017 - N°20170119897

A dendrimer formulation, such as a pamam dendrimer or a multiarm peg polymeric formulation has been developed for oral administration to the gastrointestinal tract for treatment of inflammatory diseases associated with infection or cancer. In the preferred embodiment, the dendrimers are in the form of dendrimer nanoparticles comprising poly(amidoamine) (pamam) hydroxyl-terminated dendrimers covalently linked to at least one therapeutic, ...
Method and kit for bowel preparation
Msm Innovations, Inc.
May 04, 2017 - N°20170119846

The present invention provides methods and taste-modifying kits for facilitating cleansing of the gastrointestinal tract of a patient prior to a diagnostic, surgical or therapeutic procedure. The methods and taste-modifying kits can improve patient compliance, and thus, efficacy of the preparation. Specifically, the present methods make the gastrointestinal tract preparation composition palatable for the patient to consume. For example, for ...
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