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Gastrointestinal Tract

Gastrointestinal Tract-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Proton-binding polymers for oral administration
Tricida, Inc.
January 18, 2018 - N°20180015121

Pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. The pharmaceutical compositions contain crosslinked amine polymers and may be used, for example, to treat diseases or other metabolic conditions in which removal of protons and/or chloride ions from the gastrointestinal tract would provide physiological benefits such as normalizing serum bicarbonate ...
Ingestible electrical device for stimulating tissues in a gastrointestinal tract of an organism
Carnegie Mellon University
January 11, 2018 - N°20180008825

In one aspect, an ingestible, electrical device, comprises one or more electrodes comprising a biocompatible conducting material and a biocompatible insulating material; a generator connected to the one or more electrodes; and an outer casing enclosing the one or more electrodes and the generator, the outer casing configured to dissolve in an aqueous environment of the organism; wherein the one ...
Antioxidant agent, and antioxidant cosmetic and uv care cosmetic
Ezaki Glico Co., Ltd.
January 04, 2018 - N°20180000856

The present invention provides an antioxidant, an ros inhibitor, an antioxidant enzyme production promoter, an antioxidant cosmetic, a uv care cosmetic, a prophylactic or therapeutic agent for gastrointestinal tract inflammation, and an antioxidant food or beverage, each containing an enzymatically synthesized glycogen (esg) or an α-amylase digest (rg) thereof, as well as use for enhancing an antioxidative effect ...
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Device and method for treatment of barrett's esophagus
January 04, 2018 - N°20180000616

Barrett's esophagus is a serious complication of gerd. It is characterized by the replacement of the normal stratified squamous epithelium lining of the esophagus by simple columnar epithelium with goblet cells (which are usually found lower in the gastrointestinal tract). A method comprising deploying multiple stents to cause pressure ischemia and subsequent necrosis of the mucosal layer of the esophagus ...
Upper gastrointestinal bleeding monitoring system
National Cheng Kung University
January 04, 2018 - N°20180000358

An upper gastrointestinal bleeding monitoring system includes a detection device and a signal processing device to determine bleeding condition of an upper gastrointestinal tract by using relation of time and intensity ratios of rgb three primary colors. The detecting device is placed to the upper gastrointestinal tract of a patient via his/her mouth or nasal passage and then stay ...
Probiotic bacterial molecules and their use in methods to treat/prevent infection by harmful bacteria ...
University Of Guelph
January 04, 2018 - N°20180000126

This invention provides isolated and characterized secreted molecules from probiotic bacteria for use in compositions and methods for the treatment and/or prevention of infection by harmful pathogenic bacteria. The isolated secreted molecules can also be used in nutritional or medical food products which provide probiotics to the gastrointestinal tract of a mammal.
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Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid ...
Ardelyx, Inc
December 28, 2017 - N°20170368004

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (ppar) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment ...
Tfr selective binding compounds and related methods
Ossianix, Inc.
December 07, 2017 - N°20170348416

The present invention relates to peptides that bind with high specificity and which functionally interact with the transferrin receptor (“tfr”) and which may be used in making molecular vehicles that carry biomolecules across membranes, including, e. G., across the blood brain barrier or the gastrointestinal tract. Tfr specific binding moieties may also be used alone or ...
Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid ...
Ardelyx, Inc.
November 30, 2017 - N°20170340623

The present disclosure is directed to compounds and methods for the treatment of disorders associated with fluid retention or salt overload, such as heart failure (in particular, congestive heart failure), chronic kidney disease, end-stage renal disease, liver disease, and peroxisome proliferator-activated receptor (ppar) gamma agonist-induced fluid retention. The present disclosure is also directed to compounds and methods for the treatment ...
Modulation of regulatory t cells via g-coupled protein receptor 43
President And Fellows Of Harvard College
November 30, 2017 - N°20170340588

Disclosed herein are compositions and methods that are useful for inducing the development of regulatory t cells (treg). Such compositions and methods are useful for treating inflammatory conditions and in particular inflammatory conditions affecting the gastrointestinal tract of a subject. In certain embodiments, the present inventions generally relate to short chain fatty acids and the discovery that such short chain ...
Artificial stomach
November 30, 2017 - N°20170340431

A method for surgically placing an artificial stomach in a patient. The method comprises the steps of cutting an opening in the abdominal wall of the patient, dissecting an abdominal area and placing the artificial stomach in the dissected abdominal area. The artificial stomach comprises a food reservoir adapted to collect food, an inlet connected to a first opening of ...
Devices for testing distal colonic and anorectal function
November 30, 2017 - N°20170340264

Devices for testing distal colonic and anorectal function. In at least one embodiment of a device of the present disclosure, the device comprises a flexible central support, a first bag or balloon surrounding at least part of the flexible central support; and a first plurality of sensors positioned upon or embedded within a surface of the first bag or balloon, ...
Topically active steroids for use in radiation and chemotherapeutics injury
Soligenix, Inc.
November 23, 2017 - N°20170333448

Methods of delivering corticosteroids or metabolites thereof for treating and preventing tissue damage resulting from acute radiation injury in the gastrointestinal tract with locally effective therapeutic agents.
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A process to enhance the bioactivity of ashwagandha extracts
November 16, 2017 - N°20170326195

The invention relates to an extract of ashwagandha that exhibit enhanced bioactivity and bioavailability comprising of enriched withanolide glycosides and saponins; with negligible amount of alkaloids, withanolide aglycones and oligosaccharides. The extract as disclosed prepared from root, stems, leaves and whole plant of ashwagandha further shows improved immunomodulatory activity, anti-inflammatory activity, anti stress activity, antidiabetic activity and sleep quality. The ...
Protective apparatus for use in gastrointestinal tract
Boston Scientific Scimed, Inc.
November 16, 2017 - N°20170325983

An apparatus may be used after a surgical procedure to protect against leaks and to separate healing tissue from foreign materials such as nutritional contents. In some cases the apparatus may be easily delivered to a surgical site before, during or after a surgical procedure such as gastric bypass surgery, but this is only an example. The apparatus may include ...
Gastroretentive gel formulations
Jagotec Ag
November 09, 2017 - N°20170319698

The present invention provides a gastric retentive gel composition comprising: (a) a hydrophobic or amphiphilic liquid gelled with an organogelator; (b) an active agent; and (c) a hard wax or wax-like additive, for controlled delivery of the active agent to or through the upper gastrointestinal tract, in particular to or through the stomach. The gel composition forms a stable, floating ...
Soluble, stable, anti-inflammatory, proliferative, protective and mucoadhesive pharmaceutical compositions; use thereof for treating mucositis conditions ...
Universidade Federal De Goias
November 09, 2017 - N°20170319642

The present invention relates to pharmaceutical compositions with mucoadhesive and sustained release characteristics containing the association of the extract or fractions of curcuma longa l. With curcuminoid content greater than 5% and bidens pilosa (bd) extract, which has an important proliferative and anti-inflammatory effect, for the treatment of inflammatory diseases of the oral cavity (stomatitis) and of the gastrointestinal tract, as, ...
Serum-based mirna microarray and its use in diagnosis and treatment of barrett's esophagus (be) and ...
November 02, 2017 - N°20170314080

Robust and reliable molecular diagnostic screening tools for early detection of esophageal and gastrointestinal tract cancers and pre-cancerous lesions, such as barrett's esophagus, and esophageal adenocarcinoma are provided. Included in the invention is an array of mirna probes specific for identifying, diagnosing and prognosticating esophageal and gastrointestinal tract cancers and pre-cancerous lesions in subjects from blood or serum samples. A ...
Beta-lactamases with improved properties for therapy
November 02, 2017 - N°20170314006

This invention relates to, in part, compositions of beta-lactamases and methods of using these enzymes in, for example, gastrointestinal tract (gi tract) disorders such as c. Difficile infection (cdi).
Antibacterial and protective formulations and methods for making and using them
November 02, 2017 - N°20170312322

Provided are compositions and methods for treating, ameliorating and preventing various infections, disorders and conditions in mammals, including genetically-predisposed and chronic disorders, where a microbial or bacterial flora is at least one causative or symptom-producing factor, where exemplary compositions are products of manufacture, a food, a drink, a nutraceutical, a dietary supplement, a formulation, a pharmaceutical or a pharmaceutical preparation ...
New indication of azelnidipine pharmaceutical composition for treating cancer
November 02, 2017 - N°20170312260

A method for treating a cancer includes administering to a subject in need thereof a pharmaceutical composition containing a therapeutically effective amount of azelnidipine or a pharmaceutical acceptable salt thereof. The cancer is selected from the group consisting of a pleural-related cancer, an abdominal-related cancer, an endocrine-related cancer, a gastrointestinal tract-related cancer, osteosarcoma, and skin cancer.
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