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Gastrointestinal Diseases

Gastrointestinal Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Cholic acid derivative, and preparation method and medical use thereof
Shanghai Hansoh Biomedical Co., Ltd.
May 31, 2018 - N°20180148470

The present invention relates to a cholic acid derivative, and a preparation method and a medical use thereof. In particular, the present invention relates to a cholic acid derivative of formula (i), a stereoisomer, or a pharmaceutically acceptable salt thereof.
Use of antibiotics with specific therapeutic activities combined with the simultaneous use of lactobacilli and/...
Probiotical S.p.a.
May 10, 2018 - N°20180125902

The present invention relates to the use of antibiotics with specific therapeutic activities combined with the simultaneous use of lactobacilli and/or bifidobacteria having a non-transferable antibiotic resistance and with the same therapeutic indication as said antibiotics. In particular, the present invention relates to a composition comprising or, alternatively, consisting of antibiotics suitable for the treatment of acute and chronic ...
Modulators of farnesoid x receptor and methods for the use thereof
Xiamen University
May 03, 2018 - N°20180116993

Compounds, compositions and methods are provided for treating the fxr-mediated disease or process in a mammal, comprising administering to the mammal a therapeutically effective amount of a compound claimed, wherein the fxr-mediated disease or condition linked to chronic liver diseases such as nonalcoholic fatty liver disease and nonalcoholic steatohepatitis; gastrointestinal diseases; cardiovascular diseases; metabolic diseases such as diabetes and obesity; ...
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Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
Cymabay Therapeutics, Inc.
February 08, 2018 - N°20180036307

Use of oxymethylene aryl gpr119 agonists, and optionally dpp iv inhibitors and optionally metformin, for the treatment of inflammatory gastrointestinal diseases or gastrointestinal conditions involving malabsorption of nutrients and/or fluids are provided.. .
Hydrocortisone acetate suppository formulation for treatment of disease
Criscot Llc
February 08, 2018 - N°20180036235

The present invention relates, in various embodiments, to formulations comprising hydrocortisone and silicon dioxide. In additional embodiments, the invention relates to suppositories comprising hydrocortisone and silicon dioxide.
Methods, compounds, and compositions for the treatment of angiotensin-related diseases
University Of Southern California
February 01, 2018 - N°20180030042

Disclosed are small molecule non-peptidic compounds, as well as methods and compositions for the treatment of angiotensin-related diseases and disorders, including cardiovascular diseases, metabolic diseases, gastrointestinal diseases, renal diseases, inflammatory/autoimmune diseases, neurological diseases, bone marrow diseases and cancer. In particular, the invention provides compounds, methods and compositions for the treatment of metabolic diseases and disorders, such as diabetes mellitus, ...
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Probiotic fermented cereal compositions and methods for treatment of gastrointestinal diseases caused by pro-inflammatory bacteria
Nordisk Rebalance A/s
November 23, 2017 - N°20170333514

The invention covers a novel treatment strategy that considerably improves conventional probiotic treatments of inflammatory bowel diseases, irritable bowel syndrome and other gastrointestinal disorders. Both probiotic microorganisms and the carrier of the probiotic microorganisms in form of a fermented cereal gruel are used as treatment effectors.
Piperidine compounds, pharmaceutical composition comprising the same and its use
Sk Biopharmaceuticals Co., Ltd.
September 28, 2017 - N°20170275250

Piperidine compounds and pharmaceutically useful salts thereof, a pharmaceutical composition including an effective amount of the racemic or enantiomerically enriched piperidine compounds to treat gastrointestinal diseases, and a method of treating gastrointestinal diseases in a mammal are provided.. .
Compositions and methods
Seres Therapeutics, Inc.
July 13, 2017 - N°20170196914

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .
Substituted prolines / piperidines as orexin receptor antagonists
Eolas Therapeutics, Inc.
April 13, 2017 - N°20170101410

The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as ox1 or ox2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention. ...
Piperidine compounds, pharmaceutical composition comprising the same and its use
Sk Biopharmaceuticals Co., Ltd.
December 15, 2016 - N°20160362374

Piperidine compounds and pharmaceutically useful salts thereof, a pharmaceutical composition including an effective amount of the racemic or enantiomerically enriched piperidine compounds to treat gastrointestinal diseases, and a method of treating gastrointestinal diseases in a mammal are provided.. .
Fluorinated arylalkylaminocarboxamide derivatives
Newron Pharmaceuticals S.p.a.
November 17, 2016 - N°20160332959

Fluorinated arylalkylaminocarboxamide derivatives of formula (i) are described wherein w, j, n, r1, r2, r2′, r3, r4, r5 and r6 have the meanings as defined in the specification and pharmaceutically salts thereof, pharmaceutical compositions containing them as active ingredients and their use as sodium and/or calcium channel modulators useful in preventing, alleviating and curing a wide range of ...
Use and identification of biomarkers for gastrointestinal diseases
Alfagene Bioscience, Inc.
October 27, 2016 - N°20160312290

The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug discovery, monitoring of treatment efficacy, and diagnostics. The invention further provides methods for identifying a therapeutic target to treat ulcerative colitis, colorectal cancer, and crohn's disease..
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Methods of using diaminopyrimidine p2x3 and p2x2/3 receptor modulators for treatment of respiratory ...
September 22, 2016 - N°20160271131

Wherein d, x, y, r1, r2, r3, r4, r5, r6, r7 and r8 are as defined herein.. .
Quinine compounds, and optical isomers, preparation method and medical use thereof
Beijing Fswelcome Technology Development Co., Ltd
August 25, 2016 - N°20160244439

The present invention discloses a class of quinine compounds and pharmaceutically acceptable salts, solvates, prodrugs or optical isomers thereof. Also disclosed in the present invention are that the above compounds have a selective antagonistic effect on the receptor subtypes of m1 and m3, but have no significant effect on m2 receptor subtype, and the above compounds are characterized by rapid ...
Compositions and methods for treatment and prophylaxis of gastrointestinal diseases
July 21, 2016 - N°20160206564

Methods and compositions for treating inflammatory bowel disease, irritable bowel syndrome, and travelers' diarrhea involve the use of targeted antibiotics in combination with probiotic formulations. The probiotics mitigate many of the deleterious side effects associated with antibiotic use and permit the antibiotic to be administered at a higher dose and for a longer duration than would otherwise be possible in ...
Compositions and methods
Seres Therapeutics, Inc.
July 14, 2016 - N°20160199423

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .
Compositions and methods
June 30, 2016 - N°20160184370

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.. .
Multi-tailed lipids and uses thereof
Massachusetts Institute Of Technology
June 09, 2016 - N°20160158363

The present invention provides multi-tailed lipid compounds, and salts and stereoisomers thereof, and methods of preparing the compounds. Also provided are compositions including a compound of the invention and an agent (e.g., an sirna, mrna, plasmid dna, small molecule, protein, peptide).
Composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit
Jeju Technopark
May 12, 2016 - N°20160129065

The present invention relates to a composition for preventing and treating gastrointestinal diseases by using litsea japonica, and specifically, to a composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit as an active ingredient. According to the present invention, the essential oils extracted from litsea japonica fruits (pure fruit, seed fruit, and seeds) and ...
Compositions and methods for the treatment of inflammatory bowel disease
Cellix Bio Private Limited
May 05, 2016 - N°20160120839

The invention relates to the compounds of formula i and formula ii or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i or formula ii; and methods for treating or preventing inflammatory bowel disease may be formulated for oral, buccal, rectal, topical, transdermal, ...
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