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Gastrointestinal Diseases

Gastrointestinal Diseases-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
Cymabay Therapeutics, Inc.
February 08, 2018 - N°20180036307

Use of oxymethylene aryl gpr119 agonists, and optionally dpp iv inhibitors and optionally metformin, for the treatment of inflammatory gastrointestinal diseases or gastrointestinal conditions involving malabsorption of nutrients and/or fluids are provided.
Hydrocortisone acetate suppository formulation for treatment of disease
Criscot Llc
February 08, 2018 - N°20180036235

The present invention relates, in various embodiments, to formulations comprising hydrocortisone and silicon dioxide. In additional embodiments, the invention relates to suppositories comprising hydrocortisone and silicon dioxide. The formulations of the present invention are useful for administration to patients who have gastrointestinal diseases and disorders such as, for example, inflammatory bowel disease.
Methods, compounds, and compositions for the treatment of angiotensin-related diseases
University Of Southern California
February 01, 2018 - N°20180030042

Disclosed are small molecule non-peptidic compounds, as well as methods and compositions for the treatment of angiotensin-related diseases and disorders, including cardiovascular diseases, metabolic diseases, gastrointestinal diseases, renal diseases, inflammatory/autoimmune diseases, neurological diseases, bone marrow diseases and cancer. In particular, the invention provides compounds, methods and compositions for the treatment of metabolic diseases and disorders, such as diabetes mellitus, ...
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Probiotic fermented cereal compositions and methods for treatment of gastrointestinal diseases caused by pro-inflammatory bacteria
Nordisk Rebalance A/s
November 23, 2017 - N°20170333514

The invention covers a novel treatment strategy that considerably improves conventional probiotic treatments of inflammatory bowel diseases, irritable bowel syndrome and other gastrointestinal disorders. Both probiotic microorganisms and the carrier of the probiotic microorganisms in form of a fermented cereal gruel are used as treatment effectors. Phospholipids may also be an effecter. The novel treatment strategy is capable of removing ...
Piperidine compounds, pharmaceutical composition comprising the same and its use
Sk Biopharmaceuticals Co., Ltd.
September 28, 2017 - N°20170275250

Piperidine compounds and pharmaceutically useful salts thereof, a pharmaceutical composition including an effective amount of the racemic or enantiomerically enriched piperidine compounds to treat gastrointestinal diseases, and a method of treating gastrointestinal diseases in a mammal are provided.
Compositions and methods
Seres Therapeutics, Inc.
July 13, 2017 - N°20170196914

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
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Piperidine compounds, pharmaceutical composition comprising the same and its use
Sk Biopharmaceuticals Co., Ltd.
December 15, 2016 - N°20160362374

Piperidine compounds and pharmaceutically useful salts thereof, a pharmaceutical composition including an effective amount of the racemic or enantiomerically enriched piperidine compounds to treat gastrointestinal diseases, and a method of treating gastrointestinal diseases in a mammal are provided.
Fluorinated arylalkylaminocarboxamide derivatives
Newron Pharmaceuticals S.p.a.
November 17, 2016 - N°20160332959

Fluorinated arylalkylaminocarboxamide derivatives of formula (i) are described wherein w, j, n, r1, r2, r2′, r3, r4, r5 and r6 have the meanings as defined in the specification and pharmaceutically salts thereof, pharmaceutical compositions containing them as active ingredients and their use as sodium and/or calcium channel modulators useful in preventing, alleviating and curing a wide range of ...
Use and identification of biomarkers for gastrointestinal diseases
Alfagene Bioscience, Inc.
October 27, 2016 - N°20160312290

The described invention relates to the identification of biomarkers for gastrointestinal diseases and provides methods utilizing the biomarkers for in drug discovery, monitoring of treatment efficacy, and diagnostics. The invention further provides methods for identifying a therapeutic target to treat ulcerative colitis, colorectal cancer, and crohn's disease.
Drug for disease caused by expression of periostin except eye disease, and use thereof
Aqua Therapeutics Co., Ltd.
October 20, 2016 - N°20160304866

The present invention is intended to provide a novel molecule that inhibits the expression of the periostin gene that is effective in treatment of diseases caused by the expression of periostin except for eye diseases. A drug for a disease caused by the expression of periostin except for an eye disease includes, as an expression inhibitory sequence for the periostin ...
Methods of using diaminopyrimidine p2x3 and p2x2/3 receptor modulators for treatment of respiratory ...
September 22, 2016 - N°20160271131

Wherein d, x, y, r1, r2, r3, r4, r5, r6, r7 and r8 are as defined herein.
Quinine compounds, and optical isomers, preparation method and medical use thereof
Beijing Fswelcome Technology Development Co., Ltd
August 25, 2016 - N°20160244439

The present invention discloses a class of quinine compounds and pharmaceutically acceptable salts, solvates, prodrugs or optical isomers thereof. Also disclosed in the present invention are that the above compounds have a selective antagonistic effect on the receptor subtypes of m1 and m3, but have no significant effect on m2 receptor subtype, and the above compounds are characterized by rapid ...
Compositions and methods for treatment and prophylaxis of gastrointestinal diseases
July 21, 2016 - N°20160206564

Methods and compositions for treating inflammatory bowel disease, irritable bowel syndrome, and travelers' diarrhea involve the use of targeted antibiotics in combination with probiotic formulations. The probiotics mitigate many of the deleterious side effects associated with antibiotic use and permit the antibiotic to be administered at a higher dose and for a longer duration than would otherwise be possible in ...
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Compositions and methods
June 30, 2016 - N°20160184370

Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
Multi-tailed lipids and uses thereof
Massachusetts Institute Of Technology
June 09, 2016 - N°20160158363

The present invention provides multi-tailed lipid compounds, and salts and stereoisomers thereof, and methods of preparing the compounds. Also provided are compositions including a compound of the invention and an agent (e. G., an sirna, mrna, plasmid dna, small molecule, protein, peptide). The present invention also provides methods, and kits using the compositions for delivering an agent to a subject (...
Composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit
Jeju Technopark
May 12, 2016 - N°20160129065

The present invention relates to a composition for preventing and treating gastrointestinal diseases by using litsea japonica, and specifically, to a composition for preventing and treating gastrointestinal diseases, containing essential oils extracted from litsea japonica fruit as an active ingredient. According to the present invention, the essential oils extracted from litsea japonica fruits (pure fruit, seed fruit, and seeds) and ...
Compositions and methods for the treatment of inflammatory bowel disease
Cellix Bio Private Limited
May 05, 2016 - N°20160120839

The invention relates to the compounds of formula i and formula ii or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i or formula ii; and methods for treating or preventing inflammatory bowel disease may be formulated for oral, buccal, rectal, topical, transdermal, ...
Compositions and methods for the treatment of inflammatory bowel disease
May 05, 2016 - N°20160120838

The invention relates to the compounds of formula i and formula ii or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula i or formula ii; and methods for treating or preventing inflammatory bowel disease may be formulated for oral, buccal, rectal, topical, transdermal, ...
Bicyclic derivative containing pyrimidine ring, and preparation method therefor
Yuhan Corporation
March 31, 2016 - N°20160090374

The present invention provides: a bicyclic derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof; a preparation method therefor, a pharmaceutical composition comprising the same; and a use therefor. According to the present invention, the bicyclic compound derivative comprising a pyrimidine ring, or a pharmaceutically acceptable salt thereof acts as a 5-ht4 receptor agonist, and thus can be ...
Brush-poly (glycoamidoamine)-lipids and uses thereof
March 10, 2016 - N°20160067346

Which may assist the pgal and/or a complex of the pgal and an agent to pass through cell membranes or be taken up by cells. Also provided are compositions including a described pgal and an agent (e. G., polynucleotide, small molecule, peptide, or protein). The present disclosure also provides methods, kits, and uses that include or involve the pgals ...
Compositions and methods for binding cysteinyl leukotrienes (cyslts) for treatment of disease
Lpath, Inc.
March 03, 2016 - N°20160060328

Methods are provided for using antibodies and antibody fragments that bind one or more cysteinyl leukotrienes (cyslts) for treatment of diseases, including inflammatory, respiratory and gastrointestinal diseases and conditions associated with aberrant levels of one or more cyslts. Anti-cyslt antibodies and antigen-binding antibody fragments, and compositions containing such antibodies and antibody fragments, are also provided.
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