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G Proteins

G Proteins-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Modified proteins and methods of making and using same
Life Technologies Corporation
October 12, 2017 - N°20170292156

Methods, compositions, systems, apparatuses and kits comprising modified proteins, particularly modified nucleic acid-binding proteins with altered buffering properties are provided. For example, in some embodiments, methods of forming modified proteins including one or more amino acid modifications to achieve desired pka values are described. Furthermore, the invention provides methods for using such modified proteins in ion-producing reactions, such as ion-based ...
Compositions and methods for long acting proteins
Novartis Ag
October 12, 2017 - N°20170290876

The present invention is based, in part, on the discovery of peptide tags that increase the half-life and/or mean residence time of proteins or nucleic acids in the eye. In certain aspects the invention peptide tags increase the half-life and/or mean residence time of antibodies and antigen binding fragments, therapeutic proteins, protein receptors, darpins and/or aptamers in ...
Methods to improve plant-based food and feed
Plant Sensory Systems, Llc.
October 05, 2017 - N°20170283821

The present invention describes an alternative approach to increase taurine (tau) or methionine (met) production in eukaryotes, namely by the insertion of components of a sulfur-metabolic pathway and tau- or met-binding proteins in organisms where the peptides do not exist or have not clearly been identified. The invention describes methods for the use of polynucleotides that encode functional cysteine dioxygenase (...
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G Proteins Patent Applications
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  • 271+ full patent PDF documents of G Proteins-related inventions.
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Protein labeling with cyanobenzothiazole conjugates
Promega Corporation
October 05, 2017 - N°20170283456

The invention provides compounds and methods for site-specifically labeling proteins with cyanobenzothiazole derivatives of formula i. For example, the invention provides methods for labeling the n-terminus of a protein that terminates with a cysteine residue. The invention also provides methods for isolating an n-terminally labeled protein and methods for detecting an n-terminally labeled protein.
Antigen binding proteins that bind pd-l1
Sorrento Therapeutics, Inc.
October 05, 2017 - N°20170281765

There is disclosed compositions and methods relating to or derived from anti-pd-l1 antibodies. More specifically, there is disclosed fully human antibodies that bind pd-l1, pd-l1-binding fragments and derivatives of such antibodies, and pd-l1-binding polypeptides comprising such fragments. Further still, there is disclosed nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods ...
Activin type 2 receptor binding proteins and uses thereof
Adimab, Llc
October 05, 2017 - N°20170281711

This disclosure provides actrii-binding proteins such as anti-actriia and anti-actriib antibodies, and compositions and methods for making the actrii-binding proteins. In certain aspects the actrii-binding proteins inhibit, or antagonize actrii activity. In addition, the disclosure provides compositions and methods for diagnosing and treating diseases and conditions associated muscle wasting; a fibrotic condition; an inflammatory, cardiovascular, pulmonary, musculoskeletal, neurologic, ocular, skeletal, ...
G Proteins Patent Pack
Download 271+ patent application PDFs
G Proteins Patent Applications
Download 271+ G Proteins-related PDFs
For professional research & prior art discovery
inventor
  • 271+ full patent PDF documents of G Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Method of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptor (...
Amgen Inc.
September 28, 2017 - N°20170275370

Methods of treating metabolic diseases and disorders using an antigen binding protein specific for the gipr polypeptide are provided. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy. In certain embodiments the antigen binding protein is administered in combination with a glp-1 receptor agonist.
Alpha-4-beta-7 heterodimer specific antagonist antibody
Amgen Inc.
September 28, 2017 - N°20170275365

There are disclosed alpha4beta7 heterodimer-specific antigen binding proteins, nucleic acids encoding them, and methods of making and using them.
Protein scaffolds for antibody mimics and other binding proteins
Bristol-myers Squibb Company
September 28, 2017 - N°20170275342

Disclosed herein are proteins that include an immunoglobulin fold and that can be used as scaffolds. Also disclosed herein are nucleic acids encoding such proteins and the use of such proteins in diagnostic methods and in methods for evolving novel compound-binding species and their ligands.
Rs7 antibodies
Immunomedics, Inc.
September 28, 2017 - N°20170274079

This invention relates to monovalent and multivalent, monospecific binding proteins and to multivalent, multispecific binding proteins. One embodiment of these binding proteins has one or more binding sites where each binding site binds with a target antigen or an epitope on a target antigen. Another embodiment of these binding proteins has two or more binding sites where each binding site ...
Compositions for stabilizing and delivering proteins
Therapyx, Inc.
September 28, 2017 - N°20170273909

Compositions for stabilizing and delivering proteins and/or other bioactive agents are disclosed. The bioactive agents are embedded or encapsulated in a crystalline matrix. Typically the bioactive agents are in the form of micro- or nanoparticles. The crystalline matrix confers enhanced stability to the agents embedded therein relative to other microparticulate or nanoparticulate bioactive agents. The carriers are especially useful ...
Molecules with altered neonate fc receptor binding having enhanced therapeutic and diagnostic properties
Medimmune, Llc
September 21, 2017 - N°20170267780

The present invention provides molecules, including proteins, more particularly, immunoglobulins whose in vivo half-lives are altered (increased or decreased) by the presence of an igg, constant domain, or fcrn binding fragment thereof (e. G., an fc region or hinge-fc region) (e. G., from a human iggi, e. G., human iggi), that have modifications of one or more of amino acid ...
Cd27l antigen binding proteins
Amgen Inc.
September 21, 2017 - N°20170267775

The present invention relates to cd27l antigen binding proteins, such an antibodies, polynucleotides encoding said cd27l antigen binding proteins, antibody drug conjugate compositions, and methods for diagnosing and treating diseases associated with cd27l expression.
G Proteins Patent Pack
Download 271+ patent application PDFs
G Proteins Patent Applications
Download 271+ G Proteins-related PDFs
For professional research & prior art discovery
inventor
  • 271+ full patent PDF documents of G Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Anti-mica antibodies
Innate Pharma
September 21, 2017 - N°20170267764

The present invention provides antigen-binding proteins capable of binding to human mica polypeptides. The antigen-binding proteins have increased activity in the treatment of disorders characterized by mica-expressing cells, particularly cancer.
Grilling pan for cooking proteins
G.s. Blodgett Corporation
September 21, 2017 - N°20170265672

A device for cooking proteins is provided. The device includes first and second pans. Each pan includes a base and an alignment wall. The bases each have a top surface with a non-stick coating. The alignment walls each include a cutout to provide a space for a food product to be disposed therein such that the top surface of the ...
Fungal host strains , dna constructs , and methods of use
Danisco Us Inc.
September 14, 2017 - N°20170260559

Provided are fungal host strains and recombinant dna constructs for creation and use thereof, wherein the fungal host strains are particularly stable and useful for expressing proteins, enzymes, variants and other substances of interest in a reliable or less variable fashion.
Aptamers for purifying and quantifying gelsolin and its variants
Council Of Scientific & Industrial Research
September 14, 2017 - N°20170260530

The present invention relates to novel dna aptamers capable of binding gelsolin tightly and specifically. The invention further relates to the use of these aptamers to estimate the gelsolin levels in a given sample and purify bulk quantities of tagless gelsolin and its variants. The present invention thus eliminates the use of different animals/their tissues to produce gelsolin binding ...
Multivalent antigen-binding proteins
Regeneron Pharmaceuticals, Inc.
September 14, 2017 - N°20170260293

Multivalent antigen-binding proteins comprising two or three or four or more immunoglobulin heavy chain variable domain binding domains are provided, as are methods for making them, nucleic acid constructs, and cell lines for making them. Proteins comprising two or three or four or more different heavy chain variable domains that lack an immunoglobulin variable domain are provided. Proteins comprising two ...
Tslp binding proteins
Glaxosmithkline Intellectual Property Development Limited
September 14, 2017 - N°20170260266

The present disclosure relates to tslp binding proteins that interact with particular residues of human full length tslp, or contact particular regions of human full length tslp. The invention also includes pharmaceutical compositions and medical uses of these tslp binding proteins.
Annexin a2 as immunological target
The Johns Hopkins University
September 14, 2017 - N°20170258881

Annexina2 (anxa2), a member of the annexin family of calcium-dependent, phospholipid binding proteins, is one of a panel of identified antigens recognized by the post-vaccination sera of patients who demonstrated prolonged disease-free survival following multiple vaccinations. Annexina2 is abundantly expressed in pancreatic adenocarcinomas and cell surface/membrane annexina2 increases with the progression from premalignant lesions to invasive pancreatic adenocarcinomas. The ...
Human lambda light chain mice
Regeneron Pharmaceuticals, Inc.
September 14, 2017 - N°20170258059

Genetically modified mice are provided that express human λ variable (hvλ) sequences, including mice that express hvλ sequences from an endogenous mouse λ light chain locus, mice that express hvλ sequences from an endogenous mouse κ light chain locus, and mice that express hvλ sequences from a transgene or ...
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