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G Proteins

G Proteins-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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Her1 antigen binding proteins binding to the beta-hairpin of her1
Hoffmann-la Roche Inc.
April 12, 2018 - N°20180100022

The invention relates to anti-her1 antigen binding proteins, e. G. Anti-her1 antibodies, that bind to the beta-hairpin of her1, methods for selecting these antigen binding proteins, their preparation and use as medicament.
Prostate-specific membrane antigen binding proteins and related compositions and methods
Aptevo Research And Development Llc
April 12, 2018 - N°20180100021

The present invention relates to mono-specific and multi-specific polypeptide therapeutics that specifically target cells expressing prostate-specific membrane antigen (psma) and are useful for the treatment of prostate cancer (e. G., castrate-resistant prostate cancer), tumor-related angiogenesis or benign prostatic hyperplasia (bph). In one embodiment, the multi-specific poly-peptide therapeutics bind both psma-expressing cells and the t-cell receptor complex on t cells to ...
Binding proteins and methods of use thereof
Ngm Biopharmaceuticals, Inc.
April 12, 2018 - N°20180100014

The present disclosure provides binding proteins, such as antibodies, that bind beta klotho, including human beta klotho, and methods of their use.
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G Proteins Patent Applications
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Her3 antibodies binding to the beta-hairpin of her3
Hoffmann-la Roche Inc.
April 05, 2018 - N°20180094062

The invention relates to anti-her3 antigen binding proteins, e. G. Anti-her3 antibodies, that bind to the beta-hairpin of her3, methods for selecting these antigen binding proteins, their preparation and use as medicament.
Methods of treating vitiligo using pd-1 binding proteins
Celgene Corporation
April 05, 2018 - N°20180094057

Provided herein are methods for managing, treating, or preventing vitiligo using proteins that specifically bind to programmed death-1 (pd-1) and modulate the expression and/or activity of pd-1.
Amyloid-beta binding proteins
Abbvie Inc.
April 05, 2018 - N°20180094049

The present invention relates to amyloid-beta (aβ) binding proteins. Antibodies of the invention have high affinity to aβ(20-42) globulomer or any aβ form that comprises the globulomer epitope. Method of making and method of using the antibodies of the invention are also provided.
G Proteins Patent Pack
Download 271+ patent application PDFs
G Proteins Patent Applications
Download 271+ G Proteins-related PDFs
For professional research & prior art discovery
inventor
  • 271+ full patent PDF documents of G Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Method of identifying proteins in human serum indicative of pathologies of human lung tissues
Cancer, Prevention, And Cure, Ltd.
March 29, 2018 - N°20180088126

A method of identifying proteins present in human serum which are differentially expressed between normal individuals and patients known to have non-small cell lung cancers and asthma, as diagnosed by a physician. Human serum specimens from each population are digested with trypsin or any other suitable endoproteinase and analyzed using a liquid chromatography electrospray ionization mass spectrometer. Mass spectral data ...
Nucleic acids encoding antibodies to matrix metalloproteinase 9
Gilead Biologics, Inc.
March 29, 2018 - N°20180086845

The present disclosure provides compositions and methods of use involving binding proteins, e. G., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (mmp9) protein (mmp9 is also known as gelatinase-b), wherein the binding proteins comprise an immunoglobulin (ig) heavy chain (or functional fragment thereof) and an ig light chain (or functional fragment thereof).
Synthetic avian-free egg white substitute and uses thereof
March 29, 2018 - N°20180084814

In some embodiments, the present disclosure relates to an avian-free egg white composition comprising 45-63% ovalbumin, 9-15% ovotransferrin, 0-15% ovomucoid, 3- 5% ovoglobulin g2, 3-5% ovoglobulin g3, 2. 5-5% ovomucin, 3-5% lysozyme, 1-2% ovoinhibitor, 0. 8-1. 5% ovoglycoprotein, 0. 6-1. 0% flavoprotein, 0. 3-0. 8% ovomacroglobulin, 0. 02-0. 1% avidin, and 0. 02-0. 1% cystatin. In some embodiments, the composition comprises an edible yeast and one or more of the preceding proteins. ...
Delivery of structurally diverse polypeptide cargo into mammalian cells by a bacterial toxin
The Hospital For Sick Children
March 22, 2018 - N°20180080033

There is a need for delivery platforms with robust capacity that offer the possibility to deliver diverse protein-based therapeutics into specific cells. Described herein is a platform for delivering cargo polypeptides into cells, which is based on a recombinant molecule comprising: a cargo polypeptide, a diphtheria toxin enzymatic fragment (dta), and a diphtheria toxin translocation fragment (dtb). The platform has ...
Bonding tissues and cross-linking proteins with naphthalimide compounds
Alumend, Llc
March 22, 2018 - N°20180079833

Naphthalimide compounds as used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bone tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues ...
Methods and compositions to treat and detect misfolded-sod1 mediated diseases
Promis Neurosciences Inc.
March 22, 2018 - N°20180079825

The invention provides a method for treating a medical condition, disease, or disorder mediated by a misfolded form of superoxide dismutase (sod) in a subject in need of treatment. The method optionally comprises administering to the subject a composition comprising a pharmaceutically acceptable vehicle and an agent selected from (1) an exogenous antibody or fragment thereof that binds selectively to the ...
Methods for treating obesity and nonalcoholic fatty liver disease or nonalcoholic steatohepatitis using glucagon receptor ...
Remd Biotherapeutics, Inc.
March 22, 2018 - N°20180079820

The present disclosure relates to methods for treating or preventing obesity and/or nonalcoholic fatty liver diseases (naflds) and/or nonalcoholic steatohepatitis (nash) using a glucagon receptor blocking agent. In various embodiments, the present disclosure relates to methods for treating or preventing nafld/nash using antigen binding and antagonizing proteins, e. G., fully human antibodies, that specifically bind to and ...
G Proteins Patent Pack
Download 271+ patent application PDFs
G Proteins Patent Applications
Download 271+ G Proteins-related PDFs
For professional research & prior art discovery
inventor
  • 271+ full patent PDF documents of G Proteins-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Immune repertoire sequence amplification methods and applications
Augmenta Bioworks, Inc.
March 15, 2018 - N°20180073014

The present invention relates generally to the field of immune binding proteins and method for obtaining immune binding proteins from genomic or other sources. The present invention also relates to nucleic acids encoding the immune binding proteins in which the natural multimeric association of chains is maintained in the nucleic acids and the immune binding proteins made therefrom. For example ...
Antibodies specific for sclerostin and methods for increasing bone mineralization
Ucb Pharma, S.a.
March 15, 2018 - N°20180072801

Compositions and methods relating to antibodies that specifically bind to tgf-beta binding proteins are provided. These methods and compositions relate to altering bone mineral density by interfering with the interaction between a tgf-beta binding protein sclerostin and a tgf-beta superfamily member, particularly a bone morphogenic protein. Increasing bone mineral density has uses in diseases and conditions in which low bone ...
Continuous process for separation of proteins
Orochem Technologies, Inc.
March 15, 2018 - N°20180071655

Disclosed is a continuous process for separating or extracting proteins from a low grade mixture of a protein of interest, other proteins, impurities, and salts in a continuous simulated moving bed separation process. The invention provides for direct extraction of heme protein and plant protein from a crude mixture of such proteins, other proteins, impurities and salts using the chromatographic ...
Compounds targeting proteins, compositions, methods, and uses thereof
Biotheryx, Inc.
March 08, 2018 - N°20180065952

The present invention provides modulators of protein function, to restore protein homeostasis, including cytokine, aiolos, and/or ikaros activity, and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, ...
Human lambda light chain mice
Regeneron Pharmaceuticals, Inc.
March 08, 2018 - N°20180064078

Genetically modified mice are provided that express human λ variable (hvλ) sequences, including mice that express hvλ sequences from an endogenous mouse λ light chain locus, mice that express hvλ sequences from an endogenous mouse κ light chain locus, and mice that express hvλ sequences from a transgene or ...
Readily isolated bispecific antibodies with native immunoglobulin format
Novimmune Sa
March 01, 2018 - N°20180057611

The invention relates to antigen-binding proteins or antibodies having heterodimers of heavy chains, i. E., two immunoglobulin heavy chains that differ by at least one or two amino acid(s) that allows for isolation of the antigen-binding protein based on a differential affinity of an immunoglobulin heavy chain and a modified/mutated immunoglobulin heavy chain toward an affinity reagent. The ...
Fn14 binding proteins and uses thereof
La Trobe University
March 01, 2018 - N°20180057599

The present disclosure provides proteins comprising antibody antigen binding domains that bind to fn14 and uses thereof. The present disclosure also provides methods for treating wasting disorders, such as cachexia.
Biodegradable polymer formulations for extended efficacy of botulinum toxin
Akina, Inc.
March 01, 2018 - N°20180055779

Methods for the formulation of biodegradable microparticles for delivery of protein drugs, such as botulinum toxin, have been developed. The methods include the steps of precipitating and washing proteins with organic solvent to remove water prior to dispersing in polymer-dissolved organic solvent to prevent exposure to water/solvent interfaces and maintain bioactivity of the protein drugs and fabrication of microparticles ...
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