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G Proteins patents



      
           
This page is updated frequently with new G Proteins-related patent applications. Subscribe to the G Proteins RSS feed to automatically get the update: related G RSS feeds. RSS updates for this page: G Proteins RSS RSS


Date/App# patent app List of recent G Proteins-related patents
04/16/15
20150105285
 Specific and high affinity binding proteins comprising modified sh3 domains of fyn kinase patent thumbnailnew patent Specific and high affinity binding proteins comprising modified sh3 domains of fyn kinase
The present invention relates to a method for the production of a library comprising recombinant derivatives of the sh3 domain of the fyn kinase of seq id no: 1 as well as a method for selecting from a library comprising recombinant derivatives of the sh3 domain of the fyn kinase of seq id no: 1 one or more of said derivatives having a specific binding affinity to a protein or peptide.. .
Eidgenoessische Technische Hochschule Zurich
04/16/15
20150104468
 Site-specific labeling methods and molecules produced thereby patent thumbnailnew patent Site-specific labeling methods and molecules produced thereby
The present disclosure provides methods of site-specific labeling of antibodies, using proteins having 4′-phosphopantetheinyl transferase activity that catalyze post-translational modification of peptide sequences (“peptide tags”) incorporated into one or more specific sites of an antibody of interest. Enzymatic labeling enables quantitative and irreversible covalent modification of a specific serine residue within the peptide tags incorporated into the antibody, and thus creates desirable antibody conjugates..
Irm Llc
04/16/15
20150104452
 Dual variable domain immunoglobulins and uses thereof patent thumbnailnew patent Dual variable domain immunoglobulins and uses thereof
The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.. .
Abbvie Inc.
04/09/15
20150099290
 Insertion of charge in the hydrophobic interior of proteins as a strategy for engineering ph-sensitive switches patent thumbnailInsertion of charge in the hydrophobic interior of proteins as a strategy for engineering ph-sensitive switches
Methods are provided for engineering non-naturally occurring proteins comprising artificial ph-sensitive conformational switches that respond to a change in ph by causing a global unfolding of the proteins. Non-naturally occurring proteins comprising artificial ph-sensitive conformational switches that respond to a change in ph by causing a global unfolding of the proteins are also provided..
The Johns Hopkins University
04/09/15
20150098950
 Liquid formulations of tumor necrosis factor-binding proteins patent thumbnailLiquid formulations of tumor necrosis factor-binding proteins
The invention relates to a stable, pharmaceutically acceptable, aqueous formulation of tnf-binding protein, comprising a tnf-binding protein, a buffer and an isotonicity agent.. .
Ares Trading S.a.
04/02/15
20150094453
 Isolated egg protein and egg lipid materials, and methods for producing the same patent thumbnailIsolated egg protein and egg lipid materials, and methods for producing the same
A method for separating proteins and fats from an egg mixture is disclosed herein. The method includes a step of microfiltration of the egg mixture, wherein microfiltration includes pumping across a filter an egg mixture containing egg yolk and egg whites (albumen).
Rembrandt Enterprises, Inc.
04/02/15
20150093387
 Dual variable domain immunoglobulins and uses thereof patent thumbnailDual variable domain immunoglobulins and uses thereof
The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.. .
Abbvie, Inc.
03/26/15
20150089680
 Human lambda light chain mice patent thumbnailHuman lambda light chain mice
Genetically modified mice are provided that express human λ variable (hvλ) sequences, including mice that express hvλ sequences from an endogenous mouse λ light chain locus, mice that express hvλ sequences from an endogenous mouse κ light chain locus, and mice that express hvλ sequences from a transgene or an episome wherein the hvλ sequence is linked to a mouse constant sequence. Mice are provided that are a source of somatically mutated human λ variable sequences useful for making antigen-binding proteins.
Regeneron Pharmaceuticals, Inc.
03/26/15
20150087819
 Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9) patent thumbnailAntigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
Amgen Inc.
03/26/15
20150087532
 Affinity reagents for protein purification patent thumbnailAffinity reagents for protein purification
Disclosed herein are methods and compositions for purifying proteins from crude solutions.. .
The Board Of Trustees Of The Leland Stanford Junior University
03/26/15
20150086636

Myostatin inhibition for enhancing muscle and/or improving muscle function


The present invention relates to methods for inhibiting myostatin, a regulator of muscle mass, for muscle enhancement (including inducing hypertrophy and/or hyperplasia) as well as improving muscle function (including decreasing atrophy and/or increasing endurance, force and/or strength). Some of the methods involve delivering genes to cells using gene delivery or other delivery techniques known in the art in order to inhibit myostatin.
Nationwide Children's Hospital
03/26/15
20150086563

Alpha-4-beta-7 heterodimer specific antagonist antibody


There are disclosed alpha4beta7 heterodimer-specific antigen binding proteins, nucleic acids encoding them, and methods of making and using them.. .
Amgen Inc.
03/26/15
20150086556

Anti-activin a antibodies and uses thereof


The disclosure provides compositions and methods relating to or derived from anti-activin a binding proteins, including antibodies. In particular embodiments, the disclosure provides fully human, humanized, and chimeric anti-activin a antibodies that bind human activin a, activin a-binding fragments and derivatives of such antibodies, and activin a-binding polypeptides comprising such fragments.
Amgen Inc.
03/26/15
20150086554

Dual variable domain immunoglobulin and uses thereof


The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.. .
Abbvie Inc.
03/19/15
20150080558

Chromatography matrices including novel staphylococcus aureus protein a based ligands


The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, staphylococcus aureus protein a (spa), as well as methods of using the same.. .
Emd Millipore Corporation
03/19/15
20150080248

Methods for isolating proteins


The invention generally relates to methods for isolating proteins. In certain aspects, methods of the invention involve preparing a plurality of sample preparations, each preparation including one or more intact cells.
Purdue Research Foundation
03/19/15
20150079062

Method for harvesting, processing, and storage of proteins from the mammalian feto-placental unit and use of such proteins in compositions and medical treatment


The invention provides a method of harvesting, processing and storing a plurality of proteins from a mammalian feto-placental unit. The method includes dissecting a mammalian uterus to harvest at least one component of the mammalian feto-placental unit; blast freezing the component; and storing the blast frozen component; wherein the blast frozen component includes the proteins.
03/19/15
20150079061

Method for the harvesting, processing, and storage of proteins from the mammalian feto-placental unit and use of such proteins in compositions and medical treatment


The invention provides a method of harvesting, processing and storing a plurality of proteins from a mammalian feto-placental unit. The method includes dissecting a mammalian uterus to harvest at least one component of the mammalian feto-placental unit; blast freezing the component; and storing the blast frozen component; wherein the blast frozen component includes the proteins.
03/19/15
20150079038

Selective recovery


Provided herein are methods of selective screening. In addition, various targeting proteins and sequences, as well as methods of their use, are also provided..
California Institute Of Technology
03/12/15
20150074852

Genetic loci associated with head smut resistance in maize


Head smut is one of the most devastating diseases in maize, causing severe yield loss worldwide. The present invention describes the fine-mapping of a major qtl conferring resistance to head smut.
E I Du Pont De Nemours And Company
03/12/15
20150074836

Mutations of the parkin gene, compositions, methods and uses


The invention concerns nucleic acids coding for mutated or truncated forms of the human parkin gene, or forms comprising multiplication of exons, and the corresponding proteins and antibodies. The invention also concerns methods and kits for identifying mutations of the parkin gene, and for studying compounds for therapeutic purposes..
Institut National De La Santé Et De La Recherche Médicale
03/12/15
20150072937

Chimeric peptides for the regulation of gtpases


Chimeric peptides or fusion proteins are disclosed that include a rhogap activity domain and at least one specificity domain that targets a specific rho protein. The fusion proteins can be used to inhibit any gtpase activity within a cell.
Children's Medical Center Corporation
03/12/15
20150072412

Identification of antigen or ligand-specific binding proteins


The present invention discloses novel methods for the generation, expression and screening of diverse collections of binding proteins such as antibodies or fragments thereof in vertebrate host cells in vitro, for the identification and isolation of ligand- or antigen-specific binding proteins. The methods disclosed herein allow the expression of diverse collections of binding proteins from at least one vector construct, which optionally can give rise to collections of diverse binding proteins upon transfer and expression into vertebrate host cells in situ..
4-antibody Ag
03/05/15
20150067921

Fad3 performance loci and corresponding target site specific binding proteins capable of inducing targeted breaks


A method of gene editing or gene stacking within a fad3 loci by cleaving, in a site directed manner, a location in a fad3 gene in a cell, to generate a break in the fad3 gene and then ligating into the break a nucleic acid molecule associated with one or more traits of interest is disclosed.. .
Dow Agrosciences Llc
03/05/15
20150065440

Sulfated oligosaccharide derivatives


The invention relates to novel compounds that have utility as inhibitors of heparan sulfate-binding proteins; compositions comprising the compounds, and use of the compounds and compositions thereof for the antiangiogenic, antimetastatic, anti-inflammatory, antimicrobial, anticoagulant and/or antithrombotic treatment of a mammalian subject.. .
Progen Pharmaceuticals Limited
03/05/15
20150065378

Synthetic oligonucleotides for detection of nucleic acid binding proteins


Synthetic oligonucleotides that comprise a nucleic acid binding protein binding site, pcr primer sequences, and tag sequences that do not bind to nucleic acid binding proteins, with a total length of 85-130 nucleotides are disclosed herein. Also disclosed are libraries and kits comprising the synthetic oligonucleotides as well as methods of detecting nucleic acid binding proteins in a sample using the synthetic oligonucleotides..
Oregon Health & Science University
03/05/15
20150064766

Beta-glucosidase variants


The invention relates to recombinantly produced β-glucosidase variants with enhanced thermoactivity compared to naturally occurring proteins. The invention also provides methods for producing a variant β-glucosidase polypeptide with improved thermoactivity by identifying performance sensitive positions in a target β-glucosidase polypeptide and substituting the residue at that position with a thermoactivity enhancing residue..
Codexis, Inc.
03/05/15
20150064744

Modified enterokinase light chain


The present invention is related to novel mammalian enterokinase analogues such as mammalian enterokinase light chain analogues and methods of making such. Also described herein is a method for cleaving proteins having an enterokinase cleavage site..
Novo Nordisk A/s
03/05/15
20150064688

Method of making a microfluidic device


A microfluidic device allowing for multiple discrete reactions sites and allowing for sequential reactions and sample analysis along with methods for device fabrication and use is provided. The microfluidic device provides a micro-total analysis system on a single substrate and has multiple reaction sites allowing for cascade reactions and analysis on a single chip using micro-quantities of sample and reagents.
National Science And Technology Development Agency
03/05/15
20150064211

Synthetic active peptide fragments


The present invention relates to peptide fragments which have one or more shared and/or similar amino acid sequences to amino acid sequences of specific portions of the 14 kda protein of s. Mansoni (sm14) or related fabps (fatty acid binding proteins), the peptide fragments functioning as continuous or discontinuous epitopic regions of the molecule or mimicking its biological activity.
FundaÇao Oswaldo Cruz - Fiocruz
03/05/15
20150064204

Gitr antigen binding proteins


Antigen binding proteins that activate gitr are provided. Nucleic acids encoding the antigen binding proteins and vectors and cells containing such nucleic acids are also provided.
Amgen Inc.
03/05/15
20150064201

Antigen binding proteins to oncostatin m (osm)


The present invention concerns antigen binding proteins and fragments thereof which specifically bind oncostatin m (osm), particularly human osm (hosm) and which inhibit the binding of osm to the gp130 receptor but does not directly interact with site ii residues. The invention also concerns a method of humanising antibodies.
Glaxo Group Limited
02/26/15
20150059009

Methods for making fully human bispecific antibodies using a common light chain


A genetically modified mouse is provided, wherein the mouse expresses an immunoglobulin light chain repertoire characterized by a limited number of light chain variable domains. Mice are provided that express just one or a few immunoglobulin light chain variable domains from a limited repertoire in their germline.
Regeneron Pharmaceuticals, Inc.
02/26/15
20150057243

Compositions and methods for the inhibition of methyltransferases


Methods and compositions disclosed herein relate to detecting, analyzing, isolating and inhibiting methyltransferases, methyltransferase substrates, s-adenosyl-methionine-binding proteins and rna, including for the treatment of disease.. .
Northern University
02/26/15
20150056680

Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses


The present invention concerns methods and compositions for stably tethered structures of defined compositions, which may have multiple functionalities and/or binding specificities. Particular embodiments concern homodimers comprising monomers that contain a dimerization and docking domain attached to a precursor.
Ibc Pharmaceuticals, Inc.
02/26/15
20150056634

Methods for preparing dry formulations of glucose binding protein


Methods and compositions for preparing dry formulations of glucose binding proteins (gbps) are disclosed. The gbps may be stored as a dry formulation without significant loss of activity.
Becton, Dickinson And Company
02/26/15
20150056211

Heparin-binding epidermal growth factor-like growth factor binding proteins


Provided herein are antigen binding proteins, e.g., human and/or monoclonal antibodies that have affinity for heparin-binding epidermal growth factor-like growth factor (hb-egf) and neutralize the biological functions of this growth factor.. .
Amgen, Inc.
02/26/15
20150056202

Anti-tnf/il-17 dual variable domain immunoglobulin and uses thereof


The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.. .
Abbvie, Inc.
02/19/15
20150050715

Stably tethered structures of defined compositions with multiple functions or binding specificities


The present invention concerns methods and compositions for stably tethered structures of defined compositions with multiple functionalities and/or binding specificities. Particular embodiments concern stably tethered structures comprising a homodimer of a first monomer, comprising a dimerization and docking domain attached to a first precursor, and a second monomer comprising an anchoring domain attached to a second precursor.
Ibc Pharmaceuticals, Inc.
02/19/15
20150050351

Stereoisomer peptides, their polymer conjugates, their encapsulation into nanoparticles, and uses thereof for the treatment of diseases caused by abnormal angiogenesis.


This invention discloses the creation of a novel single ligand-targeted multi-stereoisomer peptide-polymer conjugate compounds comprising a group of different synthetic and chemically modified stereoisomer peptides that have been conjugated to a biocompatible polymer carrying a peptide ligand for targeted delivery and/or encapsulated in ligand targeted polymer nanoparticles. The unique physicochemical properties of the stereoisomer peptides provide therapeutic compounds with ideal biopharmaceutical properties.
02/19/15
20150050279

B-cell receptor complex binding proteins containing t-cell epitopes


The present invention relates to a polypeptide comprising a) a binding peptide binding to at least one protein selected from the group consisting of cd22, cd19, cd20, and cd21, and b) an immunogenic peptide comprising at least one t-cell epitope for use in vaccination of a subject against b-cell hyperproliferation or for use in the modulation of the immune response in a subject. The present invention further relates to a polynucleotide and a vector encoding said polypeptide and a host cell comprising the same.
Deutsches Krebsforschungszentrum
02/19/15
20150050238

Treatment of osteoarthritis and pain


The present invention relates to the treatment of osteoarthritis and pain using il-1α and il-1β binding proteins, including anti-il-1α and anti-il-1β antibodies and engineered multivalent and multispecific il-1α and il-1β binding proteins.. .
Abbvie Inc.
02/12/15
20150045540

Multispecific stacked variable domain binding proteins


The present invention concerns multi-specific stacked variable domain binding proteins.. .
Sea Lane Biotechnologies, Llc
02/12/15
20150045358

Pharmaceutical composition for treating disorders associated with insulin resistance


A pharmaceutical composition for treating disorders associated with insulin resistance is disclosed, and the composition comprises at least one inhibitor which is an effective agent to suppress endothelin-1-stimulated resistin gene expression through decreasing the endothelin-1-stimulated phosphorylation of proteins downstream of endothelin type a receptor, wherein the downstream signaling molecules comprise erk1/2, jnks, akt, and stat3 proteins, and wherein the inhibitor is selected from at least one antagonist of the endothelin type a receptor or downstream signaling proteins.. .
National Central University
02/12/15
20150044705

Protein detection using modified cyclodextrins


A method is provided for detecting a protein using a cyclodextrin covalently linked to at least one label. The cyclodextrin can associate with the protein by sequestering an aromatic amino acid side-chain of the protein in its hydrophobic cavity.
Bio-rad Laboratories, Inc.
02/12/15
20150044214

Bispecific, tetravalent antigen binding proteins


The present invention relates to bispecific, tetravalent antigen binding proteins, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.. .
Hoffmann-la Roche, Inc.
02/12/15
20150044213

Protein sustained-release injectable formulation


The present invention provides sustained-release pharmaceutical formulations for administering proteins to the eye. In particular, the invention provides formulations comprising single chain antibodies and hydrophobic polyester hexylsubstituted poly(lactic acid) (hexpla).
Esbatech - A Novartis Company Llc
02/05/15
20150037339

Anti-activin a antibodies and uses thereof


The present invention provides antibodies that bind to activin a and methods of using the same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to activin a with high affinity.
Regeneron Pharmaceuticals, Inc.
02/05/15
20150037312

Binding proteins to the constant region of immunoglobulin g


The present invention provides polypeptides that bind to immunoglobulin g and methods for their use.. .
University Of Washington Through Its Center For Commercialization
02/05/15
20150037248

Il-1beta neutralizing human monoclonal antibodies


The present invention is directed to antigen binding proteins and in particular to il-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production..
Agency For Science, Technology And Research
01/29/15
20150031870

Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)


Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
Amgen Inc.
01/29/15
20150031581

Methods and kits for determining protein-bound biomarkers


(a) automated prepurification of the sample using an effective amount of an acid protease under conditions that allow for digestion of one or more binding proteins; (b) applying said protease-digested sample onto an on-line spe column to capture at least part of said biomarker, followed by sequential washing of the solid phase; (c) eluting a fraction comprising said biomarker directly onto a liquid chromatography (lc) column comprising an apolar stationary phase and subjecting it to lc-ms or lc-ms-ms measurements to determine the amount of at least one biomarker; and (d) quantitating the biomarker(s). Also provided are kits for use in such method, for instance in the determination of vitamin d derivatives, testosterone and/or or melatonin..
01/29/15
20150030593

Compositions of penetration-enhanced targeting proteins and methods of use


The disclosure relates to penetration-enhanced targeted proteins and their uses for therapeutics delivery.. .
Permeon Biologics, Inc.
01/22/15
20150024960

Multiple biomarker set for breast cancer diagnosis, detecting the same, and diagnosis kit for breast cancer using antibody against the same


The present invention relates to a biomarker set for diagnosing breast cancer comprising two or more protein markers of: apolipoprotein c1, apolipoprotein (a), neural cell adhesion molecule l1-like protein, carbonic anhydrase 1, and fibronectin; a method for detecting the biomarker set in a blood sample through a multiple reaction monitoring; a kit for diagnosing breast cancer comprising antibodies specific to each of the proteins of the biomarker set; and a method for detecting proteins of the marker set in a blood sample through an antigen-antibody binding reaction. The method for detecting the protein marker set in a blood sample by the mrm method or antigen-antibody binding reaction and the diagnostic kit can provide very high accuracy and sensitivity in comparison with the diagnosis method using a single marker and can very conveniently diagnose breast cancer using blood from patients, thereby being effectively used for early diagnosis of breast cancer..
Biomedieng Co., Ltd.
01/22/15
20150024462

Expanded bed adsorption methods for isolation of basic milk proteins including lactoferrin


The present disclosure relates to improved expanded bed adsorption processes for isolating proteins from milk sources. In particular embodiments, the present disclosure provides a process for isolating a milk protein, such as lactoferrin, from a milk source comprising establishing an expanded bed adsorption column comprising a particulate matrix, applying a milk source to the matrix, and eluting the lactoferrin from the matrix with an elution buffer comprising about 0.3 to about 2.0 m sodium chloride..
Mead Johnson Nutrition Company
01/22/15
20150024003

Method for the production of recombinant virus, dna constructs, recombinant virus and vaccine compositions


The purpose of the present invention is the production of recombinant virus through the cloning and expression of sequences of coding nucleotides of the whole or part of heterolog proteins, through the following method: (a) modification of the heterolog nucleotides sequences in such way they when cloned and expressed in the vector virus, the present in the 5′ region nucleotides present in the 5′ edge of the gene ns1 of this vector virus or of other virus or equivalent functional sequences, and in its 3′ region, the correspondent genome region in the whole or part of the spheres of the steam and anchor of the protein e of this vector virus or equivalent functional sequences, and not comprising the structure and the replication of the mention vector virus; (b) insertion of the modified heterolog sequences in (a) in the intergene region at the structural protein e level and of nonstructural ns1 vector virus; (c) obtention of the non pathogenic recombinant virus and owner of the immunologic properties, having the heterolog sequences integrated in the viral genome according to the insertion described in (b) and, like that, expressing the heterolog antigene in such way that it can induce an appropriate immune response. The present invention is also addressed to vaccine compositions to immune against the flavivirus and/or other pathogens..
01/22/15
20150023918

Long acting proteins and peptides and methods of making and using the same


Disclosed is a method for refolding a protein or peptide that does not contain essential disulfides and that contains at least one free cysteine residue. Also disclosed are polymer ifn-γ conjugates that have been created by the chemical coupling of polymers such as polyethylene glycol moieties to ifn-γ, particularly via a free cysteine in the protein.
Bolder Biotechnology, Inc.
01/15/15
20150018523

Unnatural reactive amino acid genetic code additions


This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal trnas, orthogonal aminoacyl-trna synthetases, orthogonal pairs of trnas/synthetases and unnatural amino acids.
The Scripps Research Institute
01/15/15
20150018440

Temperature-responsive polymer particles in protein separation applications


The present invention relates to a method for isolating proteins from a solution containing the proteins. The invention also relates to a method for the chromatographic separation of proteins.
Monash University
01/15/15
20150018233

Methods and g proteins for screening and identifying ligands of g protein-coupled receptors


Abstract of the disclosure disclosed herein are methods and compounds for screening and identifying ligands of g protein-coupled receptors (gpcrs). Also disclosed are chimeric g proteins and methods for detecting the activation or inhibition of gpcrs..
Fred Hutchinson Cancer Research Center
01/15/15
20150017694

Engineered co2-fixing chemotrophic microorganisms producing carbon-based products and methods of using the same


Disclosed herein are microorganisms containing exogenous or heterologous nucleic acid sequences, wherein the microorganisms are capable of growing on gaseous carbon dioxide, gaseous hydrogen, syngas, or combinations thereof. In some embodiments the microorganisms are chemotrophic bacteria that produce or secrete at least 10% of lipid by weight.
Kiverdi, Inc.
01/15/15
20150017686

Methods for reducing mannosyltransferase activity in lower eukaryotes


Disclosed are methods for reducing detectable mannosylation of n-linked and o-linked oligosaccharides in lower eukaryote host cells. In particular, recombinant lower eukaryote host cells are provided in which expression of the gdp-mannose transporter encoded by the vanadate resistant glycosylation 4 (vrg4) gene has been disrupted.
Merck Sharp & Dohme Corp.
01/15/15
20150017312

High protein meal and flour compostions and methods


This invention pertains to the development of a high protein oil seed flour as a replacement for both wheat based and gluten free flours used in baked, dry and liquid goods which optimizes nutrition. The seed flour is based on the novel use of processing sunflower and other oil type seeds into a flour, meal, or protein isolate to replace a significant portion of traditional and gluten free flours in food goods, including baked, dry and liquid goods.
01/15/15
20150017225

Hemostatic pad assembly kit and method


The present invention relates generally to agents and devices for promoting hemostasis and tissue sealing and, more particularly, to hemostatic pads comprising bioabsorbable scaffolds that can deliver lyophilized hemostasis promoting proteins, such as fibrinogen and thrombin, to a wound site or injured organ or tissue.. .
Ethicon, Inc.
01/15/15
20150017202

Synthetic toll-like receptor-4 (tlr-4) agonist peptides


The invention provides novel immunological adjuvants and methods for identification of such adjuvants. The invention further provides methods and compositions for eliciting an immune response to an immunogen using the novel adjuvants.
Av Theapeutics, Inc.
01/15/15
20150017168

Dual variable domain immunoglobulins and uses thereof


The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.. .
Abbvie Inc.
01/15/15
20150017123

Il-1 family variants


The present invention provides compositions and methods relating to il-1rrp2 requiring proteins.. .
Amgen Inc.
01/15/15
20150017095

Prostaglandin e2 dual variable domain immunoglobulins and uses thereof


The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.. .
Abbvie Inc.


Popular terms: [SEARCH]

G Proteins topics: G Proteins, Antibodies, Immunoglobulin, Metalloprotein, Chemotherapeutic Agent, Kinase Inhibitor, Tetrapeptide, Apoptosis Protein, Topoisomerase, Peptidomimetic, Fractionation, Medical Treatment, Chromatograph, Encapsulation, Electrospraying

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