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G Protein patents



      
           
This page is updated frequently with new G Protein-related patent applications. Subscribe to the G Protein RSS feed to automatically get the update: related G RSS feeds. RSS updates for this page: G Protein RSS RSS


Date/App# patent app List of recent G Protein-related patents
12/18/14
20140371302
 Modified mrnas encoding cell-penetrating polypeptides patent thumbnailnew patent Modified mrnas encoding cell-penetrating polypeptides
This invention relates to modified nucleic acid compositions encoding cell-penetrating polypeptides to provoke an innate immune response in a cell and methods of delivering protein-binding partners to target cells.. .
12/18/14
20140371251
 Method of inhibiting dyrk1b patent thumbnailnew patent Method of inhibiting dyrk1b
The present invention relates to a dyrk1b inhibitor for use in the treatment of cancer, wherein in said cancer and/or in cells of said cancer the hedgehog signaling pathway is activated, and in particular the activation of the hedgehog signaling pathway is independent of signaling by the g protein-coupled receptor smoothened.. .
12/18/14
20140371206
 Bromodomain inhibitors and uses thereof patent thumbnailnew patent Bromodomain inhibitors and uses thereof
The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders..
12/18/14
20140371099
 Biomarker for chronic inflammatory lung diseases patent thumbnailnew patent Biomarker for chronic inflammatory lung diseases
The invention relates to an in vitro method for the diagnosis and/or prognosis and/or evaluation of the progression of a chronic inflammatory lung disease in a subject, using the level of expression of the gpr15 g protein-coupled receptor gene as a biomarker for the disease.. .
12/18/14
20140370525
 Alpha-hemoglobin stabilizing protein antibodies and methods of use thereof patent thumbnailnew patent Alpha-hemoglobin stabilizing protein antibodies and methods of use thereof
Methods for detecting and/or imaging erythrocyte precursor cells are provided.. .
12/18/14
20140370173
 Frozen confections with improved heat shock stability patent thumbnailnew patent Frozen confections with improved heat shock stability
The present invention relates to a process for improving the heat shock resistance of frozen confections which comprises adding protein aggregates in the form of fibrils to a homogenized and pasteurized mix for frozen confection, before freezing the mix.. .
12/18/14
20140370169
 Pellets comprising starch patent thumbnailnew patent Pellets comprising starch
The invention relates to pellets comprising starch and further comprising protein. A process to make pellets of the present invention is also disclosed.
12/18/14
20140370121
 Materials and method for inhibiting replication protein a and uses thereof patent thumbnailnew patent Materials and method for inhibiting replication protein a and uses thereof
Targeting uncontrolled cell proliferation and resistance to dna damaging chemotherapeutics with at least one reagent has significant potential in cancer treatment. Replication protein a, the eukaryotic single-strand (ss) dna binding protein, is essential for genomic maintenance and stability via roles in both dna replication and repair.
12/18/14
20140370012
 Fusion proteins comprising igg2 hinge domains patent thumbnailnew patent Fusion proteins comprising igg2 hinge domains
The present invention relates to biologically active fusion proteins containing the igg2 hinge as a multimerization domain capable of multimerizing proteins, peptides and small molecules which are active or more active in multimeric form; compositions comprising such fusion proteins; and methods of making and using such fusion proteins.. .
12/18/14
20140370003
 Process for concentration of antibodies and therapeutic products thereof patent thumbnailnew patent Process for concentration of antibodies and therapeutic products thereof
The present disclosure provides a process for concentrating proteins including an ultrafiltering, a diafiltering, and a second ultrafiltering sequence, at elevated temperatures, such as above about 30° c. The disclosure also includes a process for preparing highly concentrated antibody compositions, and highly concentrated antibody products..
12/11/14
20140364458
Use of an anthranilic diamide derivatives with heteroaromatic and heterocyclic substituents in combination with a biologicalcontrol agent
In which r1, r2, r3, r4, r5, r6, a, q and n can have the definitions stated in the description, and at least one biological control agent selected from bacteria, fungi or yeasts, protozoas, viruses, entomopathogenic nematodes, and botanical extracts, or products produced by microorganisms including proteins or secondary metabolites, and optionally an inoculant, for reducing overall damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, nematodes and phytopathogens.. .
12/11/14
20140364436
Protein kinase inhibitors
As well as pharmaceutically acceptable salts, hydrates, or solvates thereof, wherein the variables are described herein. The present invention further relates to pharmaceutical compositions which comprise the compounds of formula viii, and to methods for inhibiting protein kinase and methods of treating diseases, such as cancers, inflammation..
12/11/14
20140364329
Methods for identifying protein-protein interactions
The invention generally relates to methods for identifying protein-protein interactions. In certain aspects, methods of the invention involve conducting a protein-fragment complementation assay on a sample to form a protein-protein complex between two proteins in the sample that only transiently interact under physiological conditions, separating the complexes from the sample, and analyzing a protein of the complex using a mass spectrometry technique..
12/11/14
20140364309
Active compounds combination containing fluopyram bacillus and biologically control agent
The present invention relates to active compound combinations and compostions for reducing the damage of plants and plant parts as well as losses in harvested fruits or vegetables caused by insects, nematodes or phytopathogens and which have fungicidal or nematicidal or insecticidal activity including any combination of the three activities, in particular within a composition, which comprises (a) fluopyram, (b) a spore-forming bacterium of the genera bacillus, selected from bacillus firmus, bacillus cereus, bacillus pumilis, bacillus amyloliquefaciens, bacillus subtilis strain gb03, bacillus subtilis strain qst713, and (c) at least one biological control agent, in particular bacteria, fungi or yeasts, protozoa, viruses, entomopathogenic nematodes, inoculants, botanicals and products produced by microorganisms including proteins or secondary to metabolites. Moreover, the invention relates to a method for curatively or preventively controlling insects, nematodes or phytopathogens on the plant, plant parts, harvested fruits or vegetables, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed..
12/11/14
20140363846
Process for producing cellulase mixtures from myceliophthora and related organisms
The present invention provides a fermentation process for producing a cellulase enzyme mixture comprising the steps of (a) providing a fungal cell of the genus myceliophthora or a taxonomically equivalent genus; (b) culturing the fungal cell in a submerged liquid batch culture in which the carbon source comprises about 0% of cellulase-inducing carbon source; (c) culturing the fungal cell from the batch culture from step (b) in a submerged liquid fed-batch and/or continuous culture; and (d) providing the culture of step (c) with a feed solution containing a about 100 wt % non-inducing carbon source (such as glucose, dextrose, sucrose, molasses, fructose, glycerol, xylose, or a combination thereof), wherein the feed solution is provided at a rate that maintains the concentration of non-inducing carbon source in the culture below that which would otherwise repress production of the cellulase enzyme mixture, so as to produce a culture filtrate containing at least 10 g protein/l.. .
12/11/14
20140363818
Egfr and par2 regulation of intestinal permeability
The present invention provides methods for diagnosing an immune-mediated disease, e.g., an autoimmune disease, an allergy or an inflammatory disease. Diagnosis is made by detecting a heterozygous or homozygous genotype of haptoglobin 2 or by detecting and quantifying pre-haptoglobin 2 mrna or protein.
12/11/14
20140363522
Compositions and methods for treating and/or preventing cancer by inhibiting fatty acid binding proteins
The present invention concerns methods and compositions for the inhibition or reduction of the primary tumor and metastasis by inhibition of fatty acid binding proteins.. .
12/11/14
20140363496
Compositions and methods for inducing nanoparticle-mediated microvascular embolization of tumors
Nanoparticle mediated microvascular embolization (nme) of tumor tissue may occur after systemic administration of pem, leading to widespread shutdown of vascular flow, hemorrhage, and necrosis. Pem constructs are developed that incorporate large amounts of iron-containing protein, possess high oxygen affinities, and demonstrate delayed nitric oxide binding.
12/11/14
20140363463
Shortened purification process for the production of capsular streptococcus pneumoniae polysaccharides
A shortened process for producing a solution containing substantially purified capsular polysaccharides from a cellular streptococcus pneumoniae lysate broth is described. Ultrafiltering and diafiltering a clarified s.
12/11/14
20140363448
Cdcp1 and breast cancer
The present invention relates to a method for treating breast cancer in a subject having a hyperactivation of the epidermal growth factor receptor 1 and/or 2 (egfr and/or erbb2 her2), as compared to the normal subject population, or expressing deltaher2, which method comprises the step of administering to said subject a therapeutically effective amount of a modulator of the cub domain-containing protein 1 (cdcp1).. .
12/11/14
20140363416
Methods and compositions for promoting glucose homeostasis
A method of reducing blood glucose in a subject has been developed. In preferred embodiments, the method involves administering to the subject a specific activator of endogenous mitogen-activated protein kinase kinase 6 (mkk3), mitogen-activated protein kinase kinase 6 (mkk4), mitogen-activated protein kinase kinase 6 (mkk6), p38 mitogen-activated protein kinase (p38mapk), mitogen-activated kinase-activated protein kinase 2 (mk2), or a combination thereof, in an effective amount to reduce blood glucose in a subject.
12/11/14
20140360403
Organic-inorganic composite materials as a result of biomineralization
A method for producing organic-inorganic composite materials includes at least one biomineralising protein and/or polypeptide-encoding recombinant polynucleotide being introduced into at least one host cell, preferably from the class of slime moulds, and the expressed protein and/or polypeptide influencing the formation of inorganic particles in an extracellular matrix of the host cell.. .
12/04/14
20140357854
Nucleic acid encoding antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
12/04/14
20140357853
Nucleic acid encoding antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
12/04/14
20140357852
Nucleic acid encoding antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
12/04/14
20140357851
Nucleic acid encoding antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
12/04/14
20140357850
Nucleic acid encoding antigen binding proteins to proprotein convertase subtilisin kexin type 9 (pcsk9)
Antigen binding proteins that interact with proprotein convertase subtilisin kexin type 9 (pcsk9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to pcsk9 are described.
12/04/14
20140357849
Splice switching oligomers for tnf superfamily receptors and their use in treatment of disease
The present invention relates to compositions and methods for preparing splice variants of tnfalpha receptor (tnfr) in vivo or in vitro, and the resulting tnfr protein variants. Such variants may be prepared by controlling the splicing of pre-mrna molecules and regulating protein expression with splice switching oligonucleotides or splice switching oligomers (ssos).
12/04/14
20140357612
Compounds for kinase modulation, and indications therefor
Compounds active on protein kinases and methods for regulating protein kinase pathways are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.. .
12/04/14
20140357517
Radiation exposure diagnostic marker igfbp-5, composition for radiation exposure diagnosis by measuring the expression level of the marker, radiation exposure diagnostic kit comprising the composition, and method for diagnosing radiation exposure using the marker
The present disclosure provides a composition for radiation exposure diagnosis including an agent for measuring an expression level of an insulin-like growth factor-binding protein-5 (igfbp-5) gene at an mrna or the protein and a kit for radiation exposure diagnosis. Methods of diagnosing radiation exposure as well as methods for screening an agent for enhancing radiation sensitivity or for radiation protection are disclosed.
12/04/14
20140357501
Method and system for analyzing protein or peptide
A peptide is cleaved at various bonding sites into oligopeptides or similar fragments by digestion using proteinase k (s3). The obtained fragments are separated according to their kinds by reversed-phase chromatography and fractionated (s4), and each fragment is subjected to mass spectrometry to determine its mass (s6).
12/04/14
20140357498
Compositions and methods for the detection of dna cleavage complexes
Compositions, methods, and kits for identifying protein-nucleic acid complexes, particularly dna topoisomerase ii-dna complexes, are disclosed.. .
12/04/14
20140356947
Methods and compositions for somatic cell proliferation and viability
Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding protein isolated from a medium conditioned by growth of pluripotent stem cells, such as, human embryonic stem cells, human embryonic carcinoma cells.
12/04/14
20140356911
Method for producing protein
The present invention relates to a recombinant host cell, wherein the cell is modified to increase the expression levels of ero1 and xbp1 relative to the expression levels of ero1 and xbp1 in an unmodified cell. The present invention also relates to a method of producing a recombinant protein of interest comprising expressing the recombinant protein of interest in the recombinant host cell..
12/04/14
20140356909
Il-17 binding proteins
Proteins that bind il-17 and/or il-17f are described along with their use in composition and methods for treating, preventing, and diagnosing il-17 related diseases and for detecting il-17 in cells, tissues, samples, and compositions.. .
12/04/14
20140356906
Methods and products for transfecting cells
The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using rna are disclosed.
12/04/14
20140356886
Method for measuring beta-glucan, and beta-glucan-binding protein for use in the method
Disclosed are a method for measuring βg comprising the steps of bringing a sample into contact with a βg-binding protein 1 and a βg-binding protein 2, each comprising an amino acid sequence which is identical or substantially identical to an amino acid sequence shown in any one of seq id no:4, seq id no:6, seq id no:8, seq id no:10, seq id no:14, seq id no:16, seq id no:18, or seq id no:20, and having the β-glucan binding activity, to form a complex of the βg-binding protein 1, βg in the sample and the βg-binding protein 2, measuring quantity of the complex, and determining βg concentration in the sample based on the quantity of the complex; a reagent and a kit for use in said method; a novel βg-binding protein; a nucleic acid molecule encoding the βg-binding protein; and a method for producing the aforementioned βg-binding protein.. .
12/04/14
20140356382
Exosomes for delivery of biotherapeutics
The present invention relates to exosomes, loaded with biotherapeutic protein and/or peptide and methods of producing them and to the use of such exosomes for delivering protein and/or peptide in vivo, in particular the use of such exosomes in methods of therapy.. .
12/04/14
20140356363
Antigen binding proteins that bind pd-1
There is disclosed compositions and methods relating to or derived from anti-pd-1 antibodies. More specifically, there is disclosed fully human antibodies that bind pd-1, pd-1-binding fragments and derivatives of such antibodies, and pd-1-binding polypeptides comprising such fragments.
12/04/14
20140356355
Il-17 receptor a antigen binding proteins
The present invention relates to il-17 receptor a (il-17ra or il-17r) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases mediated by il-17 receptor a activation by one or more il-17 ligands. The present invention relates to the identification of neutralizing determinants on il-17 receptor a (il-17ra or il-17r) and antibodies that bind thereto.
12/04/14
20140356281
Dual specific binding proteins directed against il-1 and/or il-17
Engineered multivalent and multispecific binding proteins that bind il-1β and/or il-17 are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease.. .
12/04/14
20140352379
Method of forming fertilizer
A system and method of forming high nutritional fertilizer form swine feces in a reservoir underneath a swine facility. A pump system has a pump that conveys the feces to a remote location where the swine feces first goes through a filter and then into a treatment tank.
11/27/14
20140350453
Bonding tissues and cross-linking proteins with naphthalimide compounds
Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bond tissues and other biomaterials together.
11/27/14
20140348856
Il-17 binding proteins
Proteins that bind il-17 and/or il-17f are described along with their use in composition and methods for treating, preventing, and diagnosing il-17 related diseases and for detecting il-17 in cells, tissues, samples, and compositions.. .
11/27/14
20140348838
Il-1 binding proteins
Proteins that bind il-1α and il-1β are described along with their use in compositions and methods for treating, preventing, and diagnosing il-1-related disorders and for detecting il-1α and il-1β in cells, tissues, samples, and compositions.. .
11/27/14
20140348835
Anti-dll4/vegf dual variable domain immunoglobulin and uses thereof
Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis, monitoring, inhibition, prevention and/or treatment of cancers, tumors, and/or other angiogenesis-dependent diseases diseases characterized by aberrant dll4 and/or vegf expression or activity.. .
11/27/14
20140348834
Il-17 binding proteins
Proteins that bind il-17 and/or il-17f are described along with their use in composition and methods for treating, preventing, and diagnosing il-17 related diseases and for detecting il-17 in cells, tissues, samples, and compositions.. .
11/27/14
20140348822
Methods and compositions to treat and detect misfolded-sod1 mediated diseases
The invention provides a method for treating a medical condition, disease, or disorder mediated by a misfolded form of superoxide dismutase (sod) in a subject in need of treatment. The method optionally comprises administering to the subject a composition comprising a pharmaceutically acceptable vehicle and an agent selected from (1) an exogenous antibody or fragment thereof that binds selectively to the misfolded form of sod, and/or (2) an immunogen that elicits production of an endogenous antibody that binds selectively to the misfolded form of sod, and/or (3) a nucleic acid sequence encoding (1) or (2).


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G Protein topics: Antibodies, Nucleic Acid, G Proteins, Nucleic Acids, Amino Acid, Polypeptide, Protein A Affinity Chromatography, Chromatography, Chromatograph, Liver Metastasis, Membrane Protein, Colorectal Carcinoma, Rectal Carcinoma, Prophylactic, Glycoprotein

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This listing is a sample listing of patent applications related to G Protein for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for G Protein with additional patents listed. Browse our RSS directory or Search for other possible listings.
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Key IP Translations - Patent Translations



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