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G Protein patents



      
           
This page is updated frequently with new G Protein-related patent applications. Subscribe to the G Protein RSS feed to automatically get the update: related G RSS feeds. RSS updates for this page: G Protein RSS RSS


Polymers and plastics derived from animal proteins

Polymers and plastics derived from animal proteins

Date/App# patent app List of recent G Protein-related patents
10/23/14
20140317777
 Cassava patent thumbnailCassava
Provided are methods for reducing levels of cyanogenic glycosides and improving protein content in plants, as well as plants containing reduced levels of cyanogenic glycosides and improved protein content. In one aspect, such methods comprise, and such plants are created via, tissue-specific expression of a storage protein such as hydroxynitrile lyase in the apoplastic space of cells of the roots and tubers of such plants..
10/23/14
20140316117
 Polymers and plastics derived from animal proteins patent thumbnailPolymers and plastics derived from animal proteins
The invention is directed to a method for preparing a polymer derived from an animal protein, such as in a feedstock derived from animal by-products. The method involves hydrolyzing proteins present in a feedstock to obtain hydrolyzed proteins, wherein hydrolysis is conducted under conditions sufficient to digest the proteins and destroy pathogens; extracting a protein fraction from the hydrolyzed proteins; and treating the protein fraction with a crosslinking reagent to form the polymer.
10/23/14
20140315784
 Binding inhibitors of the beta. transducin repeat-containing protein patent thumbnailBinding inhibitors of the beta. transducin repeat-containing protein
The present invention relates to compounds which bind to beta trans-ducin repeat-containing protein (ptrcp), and modulate the activity of 13trcp. In particular, the invention relates to compounds which demonstrate optimised binding to ptrcp.
10/23/14
20140315315
 Protein detection patent thumbnailProtein detection
The present invention relates to reagents for separating proteins from detergent, reagents for detecting proteins in the presence of a detergent, and methods of using the same. The separating reagents contain a cyclic oligomer such as cyclodextrin and a cellulose derivative such as 2-hydroxyethyl cellulose.
10/23/14
20140315214
 Chaperone interaction assays and uses thereof patent thumbnailChaperone interaction assays and uses thereof
In some aspects, the invention provides methods of identifying, detecting, and/or measuring protein-protein interactions. In some aspects, the invention provides methods of identifying and/or characterizing modulators of protein-protein interactions.
10/23/14
20140314936
 Method for extracting protein from kaniwa and protein products thereof patent thumbnailMethod for extracting protein from kaniwa and protein products thereof
Provided herein is a method for making a protein product from kaniwa. The method comprises milling the kaniwa.
10/23/14
20140314934
 Whipping agent for food products and use thereof patent thumbnailWhipping agent for food products and use thereof
The present invention relates to a whipping agent comprising protein and emulsifier for aerated food products, such as for sorbet and sherbet applications. The present invention also relates to whipped food products such as sorbets and sherbets comprising this whipping agent and a method for making the same.
10/23/14
20140314876
 Proteomics based diagnostic detection method for chronic sinusitis patent thumbnailProteomics based diagnostic detection method for chronic sinusitis
The invention provides for a proteomic approach for identification of specific bacterial protein profiles that may be used in the development of methods for the diagnosis of bacterial chronic sinusitis. The invention provides for methods for determining the presence of pathogenic bacteria in the upper respiratory tract of a subject using protein profiles of the pathogenic bacteria.
10/23/14
20140314667
 Methods of treating epidermal growth factor deletion mutant viii related disorders patent thumbnailMethods of treating epidermal growth factor deletion mutant viii related disorders
The present invention relates to methods of treating treating epidermal growth factor deletion mutant viii (egfrviii) related disorders, such as glioblastoma or anaplastic astrocyte tumors, using antigen binding proteins, including antibodies against egfrviii conjugated to a drug. Diagnostic and therapeutic formulations of such antibodies and drug conjugates thereof are also provided..
10/23/14
20140314299
 System and method for multiplexed biomarker quantitation using single cell segmentation on sequentially stained tissue patent thumbnailSystem and method for multiplexed biomarker quantitation using single cell segmentation on sequentially stained tissue
Improved systems and methods for the analysis of digital images are provided. More particularly, the present disclosure provides for improved systems and methods for the analysis of digital images of biological tissue samples.
10/23/14
20140311908
Native protein electrophoresis and methods of use
A method of characterizing proteins has been developed that includes providing a sample that contains a plurality of proteins to be characterized, wherein at least a first protein of the plurality of proteins is in its native form. Additionally, the method includes contacting the sample containing the plurality of proteins with a solution to form a sample solution, and then contacting the sample solution with a gel.
10/16/14
20140309192
Modulators of the g protein-coupled mas receptor and the treatment of disorders related thereto
That are useful in methods of treatment and alleviation of diseases and disorders of the heart, brain, kidney, immune, and reproductive system resulting from ischemia, or reperfusion subsequent to ischemia, and any downstream complication(s) related thereto. The present invention further relates to methods of treatment and alleviation of diseases and disorders of the vasculature resulting from vasoconstriction or hypertension and any downstream complication(s) resulting from elevated blood pressure and/or reduced tissue perfusion..
10/16/14
20140309185
Inhibiting g protein coupled receptor 6 kinase polypeptides
This document relates to inhibitors of g protein coupled receptor 6 kinase (grk6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.. .
10/16/14
20140309158
Compositions and methods for immunomodulation
The invention relates to methods and reagents for the treatment of immunological diseases. In particular, the invention relates to isoforms of the c4b-binding protein (c4bp) lacking beta chains as well as to fragments and peptides derived thereof and to the uses of these polypeptides for the treatment of immunological diseases such as immunoinflammatory disease, sepsis, an autoimmune disease, transplant rejection, graft-versus-host disease and a hypersensitivity disease.
10/16/14
20140309135
Remedy for diabetes
A method of screening a compound having a hypoglycemic effect (hereinafter referred to as “hypoglycemic compound”), a remedy for diabetes which contains a compound having a novel function mechanism, etc. More specifically speaking, a method of screening a hypoglycemic compound capable of binding to the β subunit of a trimeric gtp-binding protein, a remedy for diabetes comprising a hypoglycemic compound, which is characterized by being capable of binding to the β subunit of a trimeric gtp-binding protein, as the active ingredient, etc..
10/16/14
20140308700
Hydrogenase polypeptide and methods of use
Provided herein are polypeptides having hydrogenase activity. The polypeptide may be multimeric, and may have hydrogenase activity of at least 0.05 micromoles h2 produced min−1 mg protein−1.
10/16/14
20140308398
Protein fortified yogurts and methods of making
Methods of making protein-fortified yogurt products are described. The methods may include mixing a casein-containing ingredient with starting milk to make a yogurt milk, where the casein-containing ingredient has a casein-to-whey protein ratio of 82:18 or greater.
10/16/14
20140308392
Meal intended for human consumption
This invention relates to a plurality of compositions for dietary health management and its use in the prevention or treatment of cardiovascular disease or type 2 diabetes, and also in the prevention and/or management of obesity and generally in weight management and loss. Thus a meal intended for human consumption is provided, the meal comprising: (a) 250-650 kilocalories (1045-4180 kilojoules); (b) 10-50, preferably 20-50, more preferably 30-50 g fibre; (c) 10-50, preferably 10-30, more preferably 10-20 g protein; (d) 0 to 5, preferably less than 3 g starch; and (e) 0 to 2, preferably 0 to 1, most preferably 0 to 0.5 g lactose; (f) at least 20, preferably at least 30, most preferably at least 40 mg of any one flavonoid aglycone; and (g) at least 30, preferably at least 40, most preferably at least 50 mg of any one flavonoid glucoside; wherein the meal comprises 75-1000 mg of total flavonoid aglycone and flavonoid glucoside, wherein the meal comprises no more than 250 mg of any one flavonoid aglycone, wherein the meal comprises no more than 250 mg of any one flavonoid glucoside..
10/16/14
20140308287
Sur-binding proteins
Embodiments concern constructs comprising surrogate light chain sequences. In particular, embodiments concern constructs that can bind to erbb3 and aspects relating to such constructs..
10/16/14
20140308286
Dual variable domain immunoglobulins and uses thereof
The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.. .
10/16/14
20140308247
Vectors conditionally expressing protein
This invention relates to the field of therapeutics. Most specifically, the invention provides methods of generating conditionally expressing one or more proteins under the control of a gene expression modulation, system in the presence of activating ligand and uses for therapeutic purposes in animals.
10/16/14
20140308206
Fc receptor binding proteins
The disclosure relates to antibodies that bind fcrn and methods of using these antibodies.. .
10/09/14
20140303199
Inhibitors of rgs proteins
G-protein coupled receptors are a diverse group that are the target of over 50% of marketed drugs. Activation of these receptors results in the exchange of bound gdp for gtp in the gα subunit of the heterotrimeric g-protein.
10/09/14
20140303082
Selective gpcr ligands
In the past decade a great deal of structural information for class a-gpcrs (g protein-coupled receptors) has emerged. However, the structural and electronic basis of ligand selectivity for closely related receptor subtypes such as the angiotensin receptors at1ar and at2r, which present completely diverse biological functions in response to the same ligand, is poorly understood.
10/09/14
20140302593
Process for purifying vlps
Processes and compositions to produce, package, and purify virus like particles containing heterologous cargo molecules utilizing self assembling proteins and protease treatment coupled with simple precipitation and filtration methods are described.. .
10/09/14
20140302592
Protein purification by anion exchange chromatography
The present invention relates to a two-step method for the purification of divalent cation binding proteins with high yield and high purity on anion exchange resin materials, to divalent cation binding proteins obtainable by said method, and to a kit comprising means for carrying out said method.. .
10/09/14
20140302591
Protein purification by anion exchange chromatography
The present invention relates to a two-step method for the purification of divalent cation binding proteins with high yield and high purity on anion exchange resin materials, to divalent cation binding proteins obtainable by said method, and to a kit comprising means for carrying out said method.. .
10/09/14
20140302581
Methods for enhanced protein production
The present invention provides a method of increasing protein production in a cell culture by growing cells that produce the protein (e.g., the growth phase) in a perfusion cell culture to a high cell density (i.e., at least above about 40×106 cells/ml) and then switching to a protein production phase, wherein the cells are cultured in a fed-batch cell culture. The present invention further provides a method for clarifying a protein from a cell culture by adjusting the ph of the cell culture to below neutral ph (i.e., below a ph of 7) and settling the cell culture, such that the cell culture separates to form a supernatant layer and a cell-bed layer, wherein the protein is in the supernatant layer..
10/09/14
20140302224
Protein seasonings and methods of making the same
A protein seasoning and methods of making the same are provided. A formulation can be provided comprising a base combined with a protein source, which can be combined with various flavored seasonings/ingredients to form protein seasonings that can be added to different foods and/or liquids.
10/09/14
20140302070
Novel pd1 isoforms, and uses thereof for potentiating immune responses
In one embodiment, the present invention provides a new isoform of human pd1 (Δ42pd1) that contains a 42-nucleotide in-frame deletion located at exon 2 domain. Δ42pd1 does not engage pd-l1/pd-l2, and can induce the production of pro-inflammatory cytokines in one embodiment, Δ42pd1 can be used as an intramolecular adjuvant to develop a fusion dna vaccine for enhancing antigen-specific cd8+ t cell immunity and for prevention of pathogenic infection and/or cancer.
10/09/14
20140302048
Plasma kallikrein binding proteins
Plasma kallikrein binding proteins and methods of using such proteins are described.. .
10/09/14
20140302038
Multispecific and multivalent binding proteins and uses thereof
The disclosure generally provides proteins that bind two epitopes (e.g., a first and a second epitope) and that are bivalent for binding to each of the first and second epitopes. The disclosure also provides compositions comprising such proteins, nucleic acid molecules encoding such proteins and methods of making and using such proteins..
10/09/14
20140302025
Vegf-binding protein for blockade of angiogenesis
Provided are chimeric vegf-binding proteins and nucleic acids (e.g., a vector) encoding chimeric vegf-binding proteins, methods and host cells for producing these proteins and nucleic acids, and pharmaceutical compositions containing these proteins and nucleic acids. Also provided are methods of treating an angiogenic disease or disorder that include administering at least one of the chimeric vegf-binding proteins or at least one of the nucleic acids (e.g., a vector) encoding a chimeric vegf-bind ing protein..
10/09/14
20140302016
Binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind cd154 and uses thereof
This invention provides binding proteins, including antibodies, antibody derivatives and antibody fragments, that specifically bind a cd154 (cd40l) protein. This invention also provides a chimeric, humanized or fully human antibody, antibody derivative or antibody fragment that specifically binds to an epitope to which a humanized fab fragment comprising a variable heavy chain sequence according to seq id no: 1 and comprising a variable light chain sequence according to seq id no: 2 specifically binds.
10/09/14
20140301992
Compositions, methods and uses for treating solid tumors using lcmv-gp-vsv pseudotype vectors
Embodiments of the present invention relate to compositions and methods for producing recombinant vsv viruses. In accordance with these embodiments, viral vectors can include a glycoprotein gp of the lymphocyte choriomeningitis virus (lcmv) instead of the g protein of the vsv.
10/02/14
20140296492
Hla-restricted, peptide-specific antigen binding proteins
Antigen binding proteins with tcr-like paratopes, that is, with an antigen binding region specific for an hla-a2 restricted peptide are disclosed. The antigen binding proteins encompass antibodies in a variety of forms, including full-length antibodies, substantially intact antibodies, fab fragments, f(ab′)2 fragments, and single chain fv fragments.
10/02/14
20140296491
Generating metal ion binding proteins
The present invention provides for a method for generating a metal ion binding protein, the method comprising a) integrating the amino acid sequence ddd into cdr1 of a light chain variable region of an antibody or fragment thereof; and b) combining the sequence of step a) with a heavy chain variable region of an antibody or fragment thereof; and c) isolating the protein. Also provided is the use of metal ion binding proteins generated by the method of the present invention for isolation and purification of proteins and for the reversible labeling of a target molecule.
10/02/14
20140296434
Chromatography matrices including novel staphylococcus aureus protein a based ligands
The present invention relates to chromatography matrices including ligands based on one or more domains of immunoglobulin-binding proteins such as, staphylococcus aureus protein a (spa), as well as methods of using the same.. .
10/02/14
20140296243
Bromodomain inhibitors and uses thereof
The present invention relates to compounds useful as inhibitors of bromodomain-containing proteins. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders..
10/02/14
20140296156
Peptide based inhibition of capcna interaction in cancer
Peptides derived from cancer specific isoform of proliferating cell nuclear antigen (capcna, also known as cspcna) or from nmpcna-interacting proteins interfere with intracellular protein-protein interaction, thereby causing a reduction in the proliferative potential of cancer. These peptides serve as therapeutic compositions to reduce the proliferation of cancer cells and also augment existing chemotherapeutic methods..
10/02/14
20140296155
Anti-stretch mark skin cream and method for making and using thereof
A skin cream and method for making and applying the skin cream having, e.g., a copper component, an ascorbic acid component, a lipid component and a peptide component. The peptide component can include palmitoyl pentapeptide (kttls) or hydrolized serecin.
10/02/14
20140294887
Adjuvanting meningococcal factor h binding protein
Factor h binding protein (fhbp) has been proposed for use in immunising against serogroup b meningococcus (‘menb’). This antigen can be efficiently adsorbed to an aluminium hydroxyphosphate adjuvant by (i) ensuring that adsorption takes place at a ph which is equal to or below the adjuvant's point of zero charge (pzc), and/or (ii) selecting a fhbp and adjuvant with an isoelectric point/pzc within the range of 5.0 to 7, and/or (iii) selecting a fhbp with an isoelectric point above the adjuvant's pzc and using a buffer to bring the ph to within 1.2 ph units of the pzc.
10/02/14
20140294881
Proteases producing an altered immunological response and methods of making and using the same
The present invention provides novel protein variants that exhibit reduced immunogenic responses, as compared to the parental proteins. The present invention further provides dna molecules that encode novel variants, host cells comprising dna encoding novel variants, as well as methods for making proteins less allergenic.
10/02/14
20140294859
Aqueous formulation of erythropoiesis stimulating protein stabilised by antioxidants for parenteral administration
The present invention relates to stable aqueous protein formulations. In particular, disclosed herein are therapeutic protein formulations suitable for parenteral administration having one or more antioxidants..
10/02/14
20140294841
T cell receptor-like antibodies specific for a wti peptide presented by hla-a2
The present invention provides antigen binding proteins that specifically bind to wilms' tumor protein (wt1), including humanized, chimeric and fully human antibodies against wt1, antibody fragments, chimeric antigen receptors (cars), fusion proteins, and conjugates thereof. The antigen binding proteins and antibodies bind to hla-a0201-restricted wt1 peptide.
10/02/14
20140294826
Methods and compositions with a recombinant neutralizing binding protein for treating toxin exposure
Methods, compositions and kits are provided for treating a subject exposed to or at risk for exposure to a disease agent using a pharmaceutical composition including at least one recombinant binding protein or a source of expression of the binding protein, wherein the binding protein neutralizes at least one or a plurality of disease agents that are toxins, for example at least one of a ricin toxin, a shiga toxin, or an anthrax toxin.. .
10/02/14
20140294813
Tnf binding proteins
Provided are tnf binding proteins and methods of treatment using the same. Also provided are nucleic acids encoding the binding proteins and recombinant expression vectors and host cells for making such binding proteins..
10/02/14
20140294788
Methods for enhancing muscle protein synthesis following concurrent training
The present disclosure provides methods for enhancing muscle protein synthesis following physical exertion. In a general embodiment, a method for enhancing muscle protein synthesis following physical exertion is provided and includes administering to an individual a composition comprising from about 15 to about 35 g protein immediately following concurrent training.


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G Protein topics: Antibodies, Nucleic Acid, G Proteins, Nucleic Acids, Amino Acid, Polypeptide, Protein A Affinity Chromatography, Chromatography, Chromatograph, Liver Metastasis, Membrane Protein, Colorectal Carcinoma, Rectal Carcinoma, Prophylactic, Glycoprotein

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This listing is a sample listing of patent applications related to G Protein for is only meant as a recent sample of applications filed, not a comprehensive history. There may be associated servicemarks and trademarks related to these patents. Please check with patent attorney if you need further assistance or plan to use for business purposes. This patent data is also published to the public by the USPTO and available for free on their website. Note that there may be alternative spellings for G Protein with additional patents listed. Browse our RSS directory or Search for other possible listings.
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