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G Protein

G Protein-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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In vivo induced toxoplasma gondii protein for application in diagnosis, vaccine and therapy
Universiti Sains Malaysia
August 17, 2017 - N°20170234872

The present invention relates to methods of screening biological samples for the presence of t. Gondii. More particularly, the present invention relates to a sensitive and specific screening test for the presence of toxoplasmosis in subjects by using or detecting the in vivo-induced t. Gondii rap domain binding protein antigen. The invention further relates to the use of the in ...
Biosensor based on g-beta-gamma-interacting proteins to monitor g-protein activation
UniversitÉ De MontrÉal
August 17, 2017 - N°20170234870

Resonance energy transfer (ret)- or protein-fragment complement assay (pca)-based biosensors useful for assessing the activity of g-proteins are described. These biosensors are based on the competition between the got subunit and a gβγ interacting protein (βγ ip) for the binding to the gβγ dimer. These biosensors comprises (1) ...
Anti-carbamylated protein antibodies and the risk for arthritis
Academisch Ziekenhuis Leiden H.o.d.n. Lumc
August 17, 2017 - N°20170234869

Antibodies against citrullinated protein antigens (acpa) have shown their relevance for the diagnosis and possibly pathogenesis in arthritis. Described are means and methods for determining antibodies against homocitrulline-containing proteins or carbamylated proteins/peptides (anti-carp) for the classification of individuals suffering from, or at risk of suffering from, arthritis.
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Herbicide tolerant triple gene insecticidal cotton and other plants
Synthetic Genomics, Inc.
August 17, 2017 - N°20170233758

The present invention refers to the next-generation three genes cotton (gossypium hirsutum) expressing chloroplast-targeted herbicide tolerant gene resistant to broad and narrow-leaved weedicide sprays and two b. Thuringiensis insecticidal genes δ-endotoxin cry2a and vegetative insecticidal protein gene vip3a. Both cry2a and vip3a genes have different modes of action in controlling a wide spectrum of ...
Hydrocarbon synthase gene and use thereof
Toyota Jidosha Kabushiki Kaisha
August 17, 2017 - N°20170233713

A hydrocarbon synthase gene encoding protein having excellent capacity to synthesize a hydrocarbon such as alkane and novel functions is provided. The gene encodes a protein comprising an amino acid sequence comprising a motif sequence shown in seq id no: 1 and having activity of synthesizing a hydrocarbon with a carbon number one less than that of an aldehyde compound from ...
Heterodimeric antibody fc-containing proteins and methods for production thereof
Genmab A/s
August 17, 2017 - N°20170233497

Novel heterodimeric antibody-fc-containing proteins, such as bispecific antibodies, and novel methods for producing such proteins
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G Protein Patent Applications
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  • 625+ full patent PDF documents of G Protein-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
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Compositions and methods for phagocyte delivery of anti-staphylococcal agents
Janssen Biotech, Inc.
August 17, 2017 - N°20170233461

The present application generally relates to multi-specific molecules that bind to multiple bacterial virulence factors, methods for producing these binding molecules, and the use of these binding molecules to treat bacterial infections. In particular, the binding molecules comprise at least two binding domains, preferably an antibody or antibody fragment and an alternative scaffold. The first binding domain is capable of ...
Method for separating proteins from animal or human plasma, or plants, using a ph gradient ...
Janssen Biotech, Inc.
August 17, 2017 - N°20170233434

The present subject matter is directed to a method for separating proteins of plasma using ph adjustment including the steps of reconstituting fraction iii, fraction iv, or plasma paste, in water for injection; adjusting ph value to 1 and temperature from 1° c. To 30° c.; centrifuging the resulting suspension at 6,000 rpm at 2-8° c. For 20 min; collecting the resulting ...
Synthetic active peptide fragments
Fundaçao Oswaldo Cruz - Fiocruz
August 17, 2017 - N°20170232082

The present invention relates to peptide fragments which have one or more shared and/or similar amino acid sequences to amino acid sequences of specific portions of the 14 kda protein of s. Mansoni (sm14) or related fabps (fatty acid binding proteins), the peptide fragments functioning as continuous or discontinuous epitopic regions of the molecule or mimicking its biological activity. More ...
Method and apparatus for analyzing relation between drug and protein
Industry-academic Cooperation Foundation, Yonsei University
August 10, 2017 - N°20170228523

Provided are a method and an apparatus for analyzing a relation between a drug and a protein. Further, the present invention relates to drug repositioning. The method for analyzing a relation between a drug and a protein may include a protein location information inputting step of receiving protein location information representing a location where the protein included in a training ...
Biomarkers for risk prediction of mortality
Roche Diagnostics Operations, Inc.
August 10, 2017 - N°20170227552

The present invention relates to a method for predicting the risk of a subject of rapidly progressing to chronic heart failure and/or of hospitalization due to chronic heart failure and/or death. The method is based on the determination of at least one biomarker selected from the group consisting of a bnp-type peptide, igfbp7 (igf binding protein 7), a cardiac ...
Biomarkers of polycystic kidney disease and uses thereof
Genzyme Corporation
August 10, 2017 - N°20170227551

Provided herein are methods for determining the efficacy of treatment for polycystic kidney disease (pkd) in a patient, diagnosing pkd in a patient, staging pkd in a patient, and monitoring pkd in a patient. These methods include determining a single or multiple levels of one or more markers selected from the group of proliferating cell nuclear antigen (pcna), cyclin d1, ...
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
Abbvie Inc.
August 10, 2017 - N°20170226552

The present invention relates to the field of protein production and, in particular, to methods and compositions for modulating the glycosylation of recombinant proteins expressed in host cells using cell culture media supplemented with cobalt.
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G Protein Patent Applications
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  • 625+ full patent PDF documents of G Protein-related inventions.
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Chimeric antigen receptor compositions
City Of Hope
August 10, 2017 - N°20170226223

Provided herein are compositions which exhibit novel diagnostic capabilities and allow to rapidly add functionality to adoptive immunotherapy. The compositions include isolated nucleic acids encoding proteins including antibody regions capable of binding compounds including a peptidyl moiety (e. G., a meditope). The recombinant proteins provided herein are useful, inter alia, for a broad variety of therapeutic and diagnostic purposes. For ...
Dual variable domain immunoglobulins and uses thereof
Abbvie, Inc.
August 10, 2017 - N°20170226200

Engineered multivalent and multispecific binding proteins, methods of making, and their uses in the prevention, diagnosis, and/or treatment of disease are provided.
Compositions and methods for increasing muscle mass and muscle strength by specifically antagonizing gdf8 and ...
Regeneron Pharmaceuticals, Inc.
August 10, 2017 - N°20170226197

The present invention provides compositions and methods which involve specifically antagonizing gdf8 and activin a. In certain embodiments, compositions are provided which comprise a gdf8-specific binding protein and an activin a-specific binding protein. For example, the invention includes compositions comprising an anti-gdf8 antibody and an anti-activin a antibody. In other embodiments, antigen-binding molecules are provided which comprise a gdf8...
Assembly activating protein (aap) and its use for the manufacture of parvovirus particles essentially consisting ...
Medigene Ag
August 10, 2017 - N°20170226160

The present invention relates to nucleic acids encoding the novel parvoviral protein “assembly activating protein” s(aap), the encoded polypeptides, methods of producing the polypeptides, antibodies specific for aap, the use of the nucleic acids for the preparation of the polypeptides, the use of the nucleic acids or the polypeptides for the preparation of the parvoviral ...
Method for inhibiting platelet interaction with biomaterial surfaces
Medtronic Ats Medical, Inc.
August 10, 2017 - N°20170224884

A method for passivating a biomaterial surface includes modifying proteinaceous material disposed at the biomaterial surface. The passivation may be effectuated by exposing the biomaterial surface to therapeutic electrical energy in the presence of blood or plasma.
Compositions and methods useful for stabilizing protein-containing formulations
Genentech, Inc.
August 10, 2017 - N°20170224820

The invention relates to use of non-surfactant compounds including, for example, polyoxyethylene (poe) sorbitans and polyethylene glycols (pegs), for stabilizing protein-containing formulations and for the prevention of aggregation of proteins in such formulations.
Deflavored egg protein isolate, products made with protein isolates and methods of making same
Rembrandt Enterprises, Inc.
August 10, 2017 - N°20170223989

This application relates generally to the processing of egg protein isolates for use in various food, sports nutrition and nutraceutical applications, methods of making egg protein isolates, and apparatus for making egg protein isolates. More particularly, the application relates to a method of deflavoring egg products and concentrating the protein content to greater than or equal to 92% dry basis protein. ...
Mice that make vl binding proteins
Regeneron Pharmaceuticals, Inc.
August 10, 2017 - N°20170223939

Genetically modified mice and methods for making an using them are provided, wherein the mice comprise a replacement of all or substantially all immunoglobulin heavy chain v gene segments, d gene segments, and j gene segments with at least one light chain v gene segment and at least one light chain j gene segment. Mice that make binding proteins that ...
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