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G Protein

G Protein-related patent applications - as published by the U.S. Patent and Trademark Office (USPTO).


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NEW Detection of high variability regions between protein sequence sets representing a binary phenotype
Arizona Board Of Regents On Behalf Of Arizona Stat E University
June 22, 2017 - N°20170177788

A computer-based bioinformatics method for identifying protein sequence differences between sets of sequences grouped into different phenotype data sets that involves querying a database to identify common sequence motifs within a first phenotype data set and another phenotype data set of protein sequences, computing a pairwise correlation among motifs for each data set, and computing the variation between the data ...
NEW Fibrosis biomarker assay
Nordic Bioscience A/s
June 22, 2017 - N°20170176458

Methods of diagnosis or of quantitation of fibrosis are provided that comprise conducting an immunoassay to measure neo-epitope containing protein fragments naturally present in a bioflui sample, and associating an elevation of the measure in the patient above a normal level with the presence or extent of fibrosis. The immunoassay is conducted by a contacting protein fragments naturally present in ...
NEW Systems and methods for identifying protein stabilizers
The University Of Kansas
June 22, 2017 - N°20170176450

A device for studying protein conformation transformation can include a macroscopic substrate, and chaperonin proteins bound to the substrate, each chaperonin protein being capable of binding to a protein of interest during or after undergoing protein conformation transformation. The device may also include the proteins of interest bound to the substrate, where the substrate is included in a label-free assay ...
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NEW Pore-forming protein conjugate compositions and methods
The Trustees Of Columbia University In The City Of New York
June 22, 2017 - N°20170175183

The present disclosure relates to compositions and methods based on a fast, efficient chemical reaction for conjugating a pore-forming protein, such as α-hemolysin, to a biomolecule, such as antibodies, receptors, and enzymes, such as dna polymerase, and the use of such pore-forming protein conjugates in nanopore devices and methods.
NEW Emulsion chemistry for encapsulated droplets
Bio-rad Laboratories, Inc.
June 22, 2017 - N°20170175179

System, including methods, apparatus, compositions, and kits, for making and using a stabilized emulsion. A method of generating a stabilized emulsion is provided. In the method, an aqueous phase may be provided. The aqueous phase may include an effective concentration of one or more skin-forming proteins. An emulsion may be formed. The emulsion may include droplets of a dispersed phase ...
NEW Riboregulator compositions and methods of use
Trustees Of Boston University
June 22, 2017 - N°20170175111

The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink rna, and methods of their use for detecting rnas in a sample such as a well and in modulating protein synthesis and expression.
NEW G Protein Patent Pack
Download 625+ patent application PDFs
G Protein Patent Applications
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For professional research & prior art discovery
inventor
  • 625+ full patent PDF documents of G Protein-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
NEW Methods of treating nail and scalp psoriasis
Kirin-amgen, Inc.
June 22, 2017 - N°20170174772

The present invention relates to a therapeutic agent for nail and scalp psoriasis comprising an il-17 receptor a (il-17ra or il-17r) antigen binding proteins, such as monoclonal antibodies that bind il-17ra, and method of using the same.
NEW Icos binding proteins
Glaxosmithkline Intellectual Property Development Limited
June 22, 2017 - N°20170174767

The present invention relates to an icos binding protein or antigen binding portion thereof that is an agonist to human icos and does not induce complement, adcc, or cdc when placed in contact with a t cell in vivo and methods of treating cancer, infectious disease and/or sepsis with said icos binding protein or antigen binding portion thereof. Further ...
NEW Novel binding proteins for pcsk9
Daiichi Sankyo Co., Ltd.
June 22, 2017 - N°20170173112

The present disclosure relates to novel lipocalin muteins which bind to pcsk9. The disclosure also provides corresponding nucleic acid molecules encoding lipocalin muteins and methods for producing lipocalin muteins as well as their encoding nucleic acid molecules.
NEW Method of modulating protein 14-3-3 functionality by facilitating or inhibiting phosphorylation
Central Adelaide Local Health Network Inc.
June 22, 2017 - N°20170173053

The present invention relates to a method of modulating cellular activity. More particularly, the present invention provides a method of modulating apoptosis by modulating protein 14-3-3 phosphorylation and, thereby, its functionality. The present invention still further extends to methods for identifying agents capable of modulating protein 14-3-3 phosphorylation. The method and molecules of the present invention are useful, ...
Oligosaccharide modification and labeling of proteins
Life Technologies Corporation
June 15, 2017 - N°20170166943

The present invention generally relates to methods of functionalizing proteins, particularly antibodies, at oligosaccharide linkages, methods of humanizing antibodies by modifying glycosylation, as well as to novel antibodies linked to modified oligosaccharides. The invention further relates to kits that may be used to produce the antibodies of the invention.
Inducible dna binding proteins and genome perturbation tools and applications thereof
President And Fellows Of Harvard College
June 15, 2017 - N°20170166903

The present invention generally relates to methods and compositions used for the spatial and temporal control of gene expression that may use inducible transcriptional effectors. The invention particularly relates to inducible methods of altering or perturbing expression of a genomic locus of interest in a cell wherein the genomic locus may be contacted with a non-naturally occurring or engineered composition ...
Purification of proteins with cationic surfactant
Horizon Pharma Rheumatology Llc
June 15, 2017 - N°20170166873

The subject invention provides a method for purifying a target protein from a mixture comprising the target protein and contaminating protein, comprising the steps of exposing the mixture to an effective amount of a cationic surfactant such that the contaminating protein is preferentially precipitated and recovering the target protein. Proteins purified according to the method of the invention are also ...
G Protein Patent Pack
Download 625+ patent application PDFs
G Protein Patent Applications
Download 625+ G Protein-related PDFs
For professional research & prior art discovery
inventor
  • 625+ full patent PDF documents of G Protein-related inventions.
  • Exact USPTO filing data with full-text, images, drawings & claims.
  • Index pages: Table View and Image-Grid View layouts. All images in each PDF.
Composition for treating cancerous cells and a method therefor
Western Michigan University Research Foundation
June 15, 2017 - N°20170165378

A composition for treating cancerous cells in a subject having an immune system includes a virus in the yatapoxvirus genus having at least one mutation. In one embodiment, the mutation results in suppressed expression of a tnf binding protein by the virus. In another embodiment, the mutation results in suppressed expression of thymidine kinase (“tk”) by ...
Bcma antigen binding proteins
Amgen Inc.
June 15, 2017 - N°20170165373

The present invention relates to bcma (b-cell maturation antigen) antigen binding proteins, such as antibodies, polynucleotide sequences encoding said antigen binding proteins, and compositions and methods for diagnosing and treating diseases. The present invention also relates to bcma antibody drug conjugates.
Anti-tigit antigen-binding proteins and methods of use thereof
Potenza Therapeutics, Inc.
June 15, 2017 - N°20170165366

Provided herein are antigen-binding proteins (abps) that selectively bind to tigit and its isoforms and homologs, and compositions comprising the abps. Also provided are methods of using the abps, such as therapeutic and diagnostic methods.
A method of measuring antibody concentration in a sample
Valitacell Limited
June 08, 2017 - N°20170160286

A method for determining antibody concentration in a liquid sample comprising the steps of incubating in a reaction chamber the liquid sample with an antibody-binding probe comprising a generic antibody binding protein conjugated to a long life fluorescent dye to provide a reaction mixture, assaying the reaction mixture in the reaction chamber for fluorescence polarisation to detect a change in ...
Methods and compositions for detection of analytes
T2 Biosystems, Inc.
June 08, 2017 - N°20170159113

The present invention relates to methods and compositions for detecting analytes, including proteins, polysaccharides, viruses, nucleic acids and cells. The methods and compositions utilize a reporter probe, suitably a multivalent reporter probe, to detect the presence of the analytes. In embodiments, the methods and compositions can be used for non-enzymatic detection of nucleic acids.
Cell free translation system for compound screening and related uses
Prosetta Antiviral Inc.
June 08, 2017 - N°20170159097

The invention provides a cell-free system comprising not more than about 5% wheat germ extract for expressing proteins such as viral proteins and proteins required for viral capsid assembly, and proteins that assemble into multiprotein complexes in a manner analogous to viral capsids, are provided. Further provided are methods for expressing proteins such as viral proteins, proteins required for capsid assembly, ...
Recombinant microorganisms for the enhanced production of mevalonate, isoprene, isoprenoid precursors, isoprenoids, and acetyl-coa-derived products
Danisco Us Inc.
June 08, 2017 - N°20170159074

The invention features compositions and methods for the increased production of mevalonate, isoprene, isoprenoid precursor molecules, isoprenoids, and/or acetyl-coa-derived products in recombinant microorganisms by engineering the microorganisms to comprise one or more acetylating proteins such that the expression and/or activity of the one or more acetylating proteins is modulated.
Engineered nucleic acid-targeting nucleic acids
Caribou Biosciences, Inc.
June 08, 2017 - N°20170159073

The present disclosure provides engineered polynucleotide sequences that form scaffolds and nucleoprotein complexes comprising such engineered polynucleotide sequences that form scaffolds and nucleic acid binding proteins. Nucleic acid sequences encoding the engineered polynucleotide sequences that form scaffolds, as well as expression cassettes, vectors and cells comprising such polynucleotide sequences, are described. A variety of methods for making and using the ...
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