|| List of recent Fusion-related patents
|Methods and systems for structural health monitoring|
Methods and apparatus for structural health monitoring are described. In one example, a method for use in designing a structural health monitoring (shm) system for use in monitoring a host structure is described.
|Method of monitoring diving and a system for monitoring or planning a dive|
The invention concerns a method, device and computer program product for monitoring or planning a dive of a diver. The method includes providing data on the composition of gases breathed by the diver during the dive, providing data on the depth or ambient pressure of the diver, and using a model to provide a safe ascent profile for the diver based on the data on the composition of gases and on the depth or ambient pressure.
|Method for determining the position of moving objects|
Method for determining the position of moving objects, wherein the object has a sensor or an apparatus for determining odometry data, having the steps of: transmitting the odometry data to a calculation device, estimating the location and position of the object with the aid of the calculation device, creating a diffusion matrix on the basis of the estimated location and position taking into account environmental data, determining a contour line on the basis of the diffusion matrix, determining the distances between the position and the contour line for different orientations, in particular each orientation, and calculating a probability density function on the basis of the distances determined.. .
|Gnss/imu positioning, communication, and computation platforms for automotive safety applications|
A gnss/imu safety sensor platform is disclosed consisting of data fusion processors, gnss acquisition and tracking processors, mems imu sensors, one or multiple accelerometers able to provide orientation information, optional v2v communication modules, and optional v2i communication modules. The data fusion processors provide interface ports to gnss/imu processors, odometers, video (visual/infrared) cameras installed in the vehicle, v2v relative positioning sensors (laser, radar or any other distance measuring), and v2v and v2i communication modules.
|System and method for performing a transiliac approach for l5-s1 discectomy and fusion|
A system, device and method for performing a transiliac approach for l5-s1 interbody fusion is disclosed. The surgeon may determine the access location using a neuromonitoring probe and fluoroscopy.
|System and method for dynamic vertebral stabilization|
An intervertebral stabilization device and method is disclosed. The device preferably includes a planar spring enclosed within a housing.
|Infusion set with safety device|
An infusion set includes a base with a rigid piercing cannula or a soft catheter and rigid introducer needle. The infusion set also includes a line set with a fluid connector.
|Infusion device with a grooved piston channel wall|
An apparatus for delivering a fluid includes a housing, an inlet in the housing for receiving the fluid, and an outlet in the housing for discharging the fluid. A piston channel is provided within the housing through which the fluid flows from the inlet to the outlet.
An infusion pump includes a pump body for holding a roller clamp 7, and a roller movement mechanism 3 for moving a roller 72 of the roller clamp 7 and operating in coordination with manipulation of a door lock mechanism. When the door lock mechanism is in an unlocked state, an infusion tube t is blocked by the roller clamp 72.
|Infusion site leak detection device|
An infusion set or patch pump is provided for delivering a pharmaceutical agent, such as insulin, to a patient. The infusion set or patch pump has a recessed portion in the bottom face containing a hydrogel and a reactant capable of producing a color change upon contact with the pharmaceutical agent.
|System and method for communication with an infusion device|
It may desirable to monitor or control a pump remotely. For example, the pump may be positioned near the patient, with remote control or monitoring of the pump occurring in a control room.
|Inhalant delivery system for massage apparatus|
A inhalant delivery system for supplying oxygen or another harmless gas to a user positioned on a massage apparatus such as a massage table or massage chair. A plenum having exit openings conforms generally to the inner periphery of a headrest of the massage apparatus such that the exit openings direct the oxygen or other harmless gas toward the nostrils of the user.
|Pulse oximeter probe-off detector|
A processor provides signal quality based limits to a signal strength operating region of a pulse oximeter. These limits are superimposed on the typical gain dependent signal strength limits.
|Targeted nuclear fusion tumor therapy|
A method and apparatus for treating a tumor in a patient. In one embodiment, the method comprises the steps of: dosing the patient with a substituted tumor-specific agent and irradiating the tumor with energetic ions, the ions having sufficient energy to penetrate into the tumor and cause nuclear fusion reactions, but not to pass through the tumor.
|Novel fluorine-18 labeled rhodamine derivatives for imaging with positron emission tomography|
The present invention is directed toward novel fluorine-18 labeled rhodamine dye derivatives and methods of making the same. The present invention is also directed toward methods of using novel fluorine-18 labeled rhodamine dye derivatives as positron emission tomography imaging agents and myocardial perfusion imaging agents..
|Methods and compositions for treating mammalian nerve tissue injuries|
To achieve, an in vivo repair of injured mammalian nerve tissue, an effective amount of a biomembrane fusion agent is administered to the injured nerve tissue. The application of the biomembrane fusion agent may be performed by directly contacting the agent with the nerve tissue at the site of the injury.
|Injectable formulation for treatment and protection of patients having an inflammatory reaction or an ischemia-reperfusion event|
The present invention relates to compounds according to formula (i) for medical use. The compounds are particularly suitable for the treatment and/or prevention of a medical condition involving hypoxic, anoxic and/or inflamed mammalian tissue.
|Gene delivery vehicles in the treatment of neurodegenerative diseases|
Currently no therapies that provide either protection or restoration of neuronal function for adult onset neurodegenerative diseases such as parkinson's disease exist. Many clinical efforts to provide such benefits by infusion of neurotropic factors have failed.
|Once-a-week administration of 25-hydroxy vitamin d3 to sustain elevated steady-state pharmacokinetic blood concentration|
An oral dosage form comprising a single dose of 25-hydroxy-vitamin d3 sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days and a pharmaceutically suitable oral carrier system, wherein subsequent single doses at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed. A method of elevating and sustaining the blood level concentration of 25-hydroxy-vitamin d3 in a human in need thereof comprising orally administering or parenterally administering by injection or infusion, at least once every 7 days, a single dose of 25-hydroxy-vitamin d3 sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days, wherein the single doses orally administered at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed.
|Unit dosage of apadenoson|
The present invention provides a unit dosage of apadenoson, a pharmacological stress agent, and use of the same as a pharmacologic agent for myocardial perfusion imaging.. .
|Three dimensional semiconductor memory devices and methods of forming the same|
Provided are three-dimensional semiconductor memory devices and methods of forming the same. The device includes a substrate, conductive patterns stacked on the substrate, and an active pattern penetrating the conductive patterns to be connected to the substrate.
|Magic angle spinning nuclear magnetic resonance apparatus and process for high-resolution in situ investigations|
A continuous-flow (cf) magic angle sample spinning (cf-mas) nmr rotor and probe are described for investigating reaction dynamics, stable intermediates/transition states, and mechanisms of catalytic reactions in situ. The rotor includes a sample chamber of a flow-through design with a large sample volume that delivers a flow of reactants through a catalyst bed contained within the sample cell allowing in-situ investigations of reactants and products.
|Enhanced oxygen cell culture platforms|
Provided is a cell culture apparatus for culturing cells, that provides enhanced oxygen delivery and supply to cells without the need for stirring or sparging. Oxygen diffusion occurs on both sides of the culture vessel, top and bottom.
|Methods and systems for optimizing perfusion cell culture system|
Methods and perfusion culture systems are disclosed. The systems and methods relate to decreasing the starting perfusion rate, resulting in increased residence time of the cells in the bioreactor and the cell retention device, and/or concomitantly increasing the starting bioreactor volume or decreasing the starting cell retention device volume, or both.
|Non-naturally occurring t cell receptors|
A t cell receptor (tcr) having the property of binding to the gp100 ylepgpvta peptide-hla-a2 complex and comprising a tcr alpha variable domain and/or a tcr beta variable domain, characterized in that the domains are mutated relative to a tcr having the extracellular alpha and beta chain sequences seq id nos: 2 and that the tcr has a binding affinity for, and/or a binding half-life for, the ylepgpvta-hla-a2 complex at least double that of a reference tcr. Embodiments of the invention such as the use of such tcrs in adoptive therapy, and fusions of such tcrs with therapeutic agents are also described..
|Bacteriorhodopsin fusion membrane protein expression system|
An expression vector is disclosed, which comprises: a) a polynucleotide sequence encoding a bacteriorhodopsin or a mutant bacteriorhodopsin; b) a multiple cloning site; c) a t7 promoter, d) a polyhistidine tag; e) a first protease cleavage site; f) optionally a second protease cleavage site; and g) optionally a linker; wherein the mutant bacteriorhodopsin comprises the residue corresponding to asn94 of seq id no: 1. Also disclosed is a fusion membrane protein expression system, which comprises: a) a polynucleotide sequence encoding a mutant haloarcula marismortui bacteriorhodopsin/d94n (hmbri/d94n) or a haloquadratum walsbyi bacteriorhodopsin (hwbr); b) a target membrane protein; and c) a t7 promoter, operably linked to the mutant hmbri/d94n or hwbr and the target membrane protein.
|Brazed articles and methods of making the same|
An article comprising a substrate, the substrate having a surface; a diffusion barrier layer disposed on a portion of the surface of the substrate, a brazing layer disposed on the diffusion barrier layer, the brazing layer comprising at least one diffusible element, wherein the diffusion barrier layer inhibits the at least one diffusible element from diffusing into the diffusion barrier layer and the substrate. Also provided herein is a method of making an article comprising providing a substrate, the substrate having a surface; forming a diffusion barrier layer on a portion of the surface of the substrate, the diffusion barrier layer being formed by electro-spark deposition; forming a brazing layer on the diffusion barrier layer, the brazing layer comprising at least one diffusible element, wherein the diffusion barrier layer inhibits the at least one diffusible element from diffusing into the substrate..
|Microparticle formulations for delivery to the lower and central respiratory tract and methods of manufacture|
Microparticle formulations of a sialidase fusion protein are produced by contacting an aqueous solution of a protein or other active agent with an organic solvent, a counterion and a scavenging agent, and chilling the solution. The microparticles are useful for preparing stable, uniform pharmaceuticals of predetermined defined dimensions..
|Biopassivating membrane stabilization by means of nitrocarboxylic acid-containing phospholipids in preparations and coatings|
The present invention relates to nitro-carboxylic acid (s)-containing phospholipids, to be used for coating of medical devices such as stents, catheter balloons, wound pads or surgical suture material and for bio-passivating compositions, such as rinses, waterproofing solutions, coating solutions, cryoprotection solutions, cold preservation media, lyoprotection solutions, contrast media solutions, preservation and reperfusion solutions containing these compounds as well as preparing solutions thereof and coating medical devices as well as their uses.. .
|New dendritic cell co-stimulatory molecules|
A novel costimulatory protein molecule, b7-dc, which is a member of the b7 family, is described as is dna coding therefor and expression vectors comprising this dna. B7-dc protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing b7-dc are useful in vaccine compositions and methods.
|Ctla4 fusion proteins for the treatment of diabetes|
A method of treating, preventing, or delaying the progression of type 1 diabetes mellitus autoimmunity by administering an effective amount of a cytotoxic t-lymphocyte-associated antigen 4 (ctla4) molecule is provided herewith. The ctla4 molecule may be a fusion protein of a ctla4 extracellular region and an immunoglobulin, such as abatacept..
|Method of use and preparation of hsa fusion protein composition for skincare|
The present invention provides a recombinant fusion protein which stimulates the rejuvenation and reactivation of skin and epidermal cells for improving skin appearance, smoothing wrinkles and freckles, and whitening skin. Particularly, the present invention provides various types of products for improving skin, which contain recombinant fusion protein of human serum albumin (hsa) with cytokine peptides (egf, fgf, kgf, hgh, hgf, pdgf, gcsf, interferon, il-11 or igf) by genetic engineering technology.
|Method for preparing of spinel lithium titanium oxide nanofiber for negative electrode of lithium secondary battery|
Disclosed is a method of preparing spinel lithium titanium oxide nanofibers for a negative electrode of a lithium secondary battery, including (s1) mixing an organic material selected from the group consisting of polyvinylpyrrolidone, polymethylmethacrylate, polyethylene, polyethylene oxide and polyvinyl alcohol, a lithium precursor, and a titanium precursor with a solvent, thus preparing a mixture solution, (s2) electrospinning the mixture solution, thus preparing composite nanofibers, and (s3) heat-treating the composite nanofibers, thus removing the organic material. In the spinel lithium titanium oxide nanofibers for a negative electrode of a lithium secondary battery prepared using the method according to the present invention, the spinel lithium titanium oxide nanofibers can provide a large surface area per unit volume, thus increasing the contact area between the electrolyte and the conductor and decreasing the lithium ion diffusion distance, thereby greatly contributing to improving electronic conductivity and ionic conductivity..
|Blood perfusion system|
An extracorporeal blood perfusion system includes a disposable assembly and a control unit having a control interface region. The interface region includes pump assemblies for selective pumping of venous blood, arterial blood, cardioplegia solution, suctioned blood and blood removed from the left ventricle.
|Gas turbine engine components with lateral and forward sweep film cooling holes|
An engine component includes a body having an internal surface and an external surface, the internal surface at least partially defining an internal cooling circuit. The engine component further includes a plurality of cooling holes formed in the body and extending between the internal cooling circuit and the external surface of the body.
|Single pass rf driver|
The disclosed embodiments relate to ion delivery mechanisms, e.g., for fusion power. Particularly, some embodiments relate to systems and methods for delivering ions to a fuel source in such a manner to initiate fast ignition.
|Apparatus and methods to perform read-while write (rww) operations|
Subject matter disclosed herein relates to methods and apparatus, such as memory devices and systems including such memory devices. In one apparatus example, a plurality of block configurations may be employed.
|Control of timing for animations in dynamic icons|
Dynamic icons are described that can employ animations, such as visual effects, audio, and other content that change with time. If multiple animations are scheduled to occur simultaneously, the timing of the animations can be controlled so that timing overlap of the animations is reduced.
|Semiconductor device having a self-forming barrier layer at via bottom|
An approach for forming a semiconductor device is provided. In general, the device is formed by providing a metal layer, a cap layer over the metal layer, and an ultra low k layer over the cap layer.
|Semiconductor alloy fin field effect transistor|
Semiconductor alloy fin structures can be formed by recessing a semiconductor material layer including a first semiconductor material to form a trench, and epitaxially depositing a semiconductor alloy material of the first semiconductor material and a second semiconductor material within the trench. The semiconductor alloy material is epitaxially aligned to the first semiconductor material in the semiconductor material layer.
|Method for depositing a low-diffusion tialn layer and insulated gate comprising such a layer|
A method for forming an aluminum titanium nitride layer on a wafer by plasma-enhanced physical vapor deposition including a first step at a radio frequency power ranging between 100 and 500 w only, and a second step at a radio frequency power ranging between 500 and 1,000 w superimposed to a d.c. Power ranging between 500 and 1,000 w.
A semiconductor device includes a first planar semiconductor (e.g., silicon) layer, first and second pillar-shaped semiconductor (e.g., silicon) layers, a first gate insulating film, a first gate electrode, a second gate insulating film, a second gate electrode, a first gate line connected to the first and second gate electrodes, a first n-type diffusion layer, a second n-type diffusion layer, a first p-type diffusion layer, and a second p-type diffusion layer. A center line extending along the first gate line is offset by a first predetermined amount from a line connecting a center of the first pillar-shaped semiconductor layer and a center of the second pillar-shaped semiconductor layer..
|Method for producing semiconductor device and semiconductor device|
A method for producing a semiconductor device includes forming a fin-shaped silicon layer, a first insulating film around the fin-shaped silicon layer, a pillar-shaped silicon layer on the fin-shaped silicon layer, a gate electrode and a gate insulating film around the pillar-shaped silicon layer, a gate line connected to the gate electrode, a first diffusion layer in an upper portion of the pillar-shaped silicon layer, a second diffusion layer in a lower portion of the pillar-shaped silicon layer and an upper portion of the fin-shaped silicon layer, and a first silicide and a second silicide on the first diffusion layer and the second diffusion layer; an interlayer insulating film to expose an upper portion of the pillar-shaped silicon layer; etching the interlayer insulating film to form a contact hole; depositing a metal to form the first contact on the second silicide; and performing etching to form the metal wire.. .
|Magnetic random access memory and a method of fabricating the same|
An aspect of the present embodiment, there is provided magnetic random access memory device including a semiconductor substrate, a selection transistor on the semiconductor substrate, the selection transistor including a diffusion layer, a contact plug on diffusion layer, an amorphous film on the contact plug, a lower electrode provided on the amorphous film, a first magnetic layer, a nonmagnetic layer, a second magnetic layer, an upper electrode stacked in an order and a sidewall contact film on the contact plug, the sidewall contact film being in contact with a sidewall of the upper electrode.. .